Search

Your search keyword '"Timmermans, I.A.L."' showing total 19 results
Start Over Author "Timmermans, I.A.L."
19 results on '"Timmermans, I.A.L."'

1. Social inhibition and emotional distress in patients with coronary artery disease: The type D personality construct

Author

Timmermans, I.A.L., Versteeg, H., Duijndam, S.N.C., Graafmans, C., Polak, P., Denollet, J., Timmermans, I.A.L., Versteeg, H., Duijndam, S.N.C., Graafmans, C., Polak, P., and Denollet, J.

Abstract

We examined the validity of the social inhibition component of Type D, its distinctiveness from negative affectivity, and value regarding emotional distress as measured with the DS14 in 173 coronary artery disease patients. In dimensional analysis, social inhibition and negative affectivity emerged as distinct traits. Analysis of continuous negative affectivity and social inhibition measures showed main effects for several emotional and inhibition markers and an interaction effect for social anxiety. Categorical analysis indicated that Type D patients reported more depression, negative mood, social anxiety, and less positive mood. Social inhibition is not a redundant trait, but has additional conceptual value

Published
2019

2. Keeping pace: Living with heart failure and an implantable cardioverter defibrillator

Author

Timmermans, I.A.L., Doevendans, Pieter A., Denollet, J.K.L., Meine, Mathias, Versteeg, Henneke, and University Utrecht

Subjects
implantable cardioverter defibrillator, patient-reported outcomes, Heart failure, remote monitoring
Abstract

The use of implantable cardioverter defibrillators (ICDs) has proven to be effective in treating cardiac arrhythmias in subgroups of patients with heart disease, and has become the treatment of choice in the prevention of sudden cardiac death. Expanding indications for primary prevention led to an increase in ICD implants, with approximately 5.000 new implants per year in the Netherlands alone. Over the past years, the impact of ICD therapy on patients’ psychosocial wellbeing received more and more attention in research and clinical practice. However, insight into the patient perspective is still limited in some areas, especially with regard to the driving restrictions and remote patient monitoring. This dissertation aims to further enhance the understanding of the patient perspective on heart failure and ICD therapy. The first part discusses patients’ illness perceptions, their emotional responses to ICD implantation in general and to the subsequent driving restrictions, and describes the feasibility of a psycho-educational group program. The second part is devoted to the patient perspective on remote device follow-up in particular. This dissertation reports findings from three studies; the European multicenter REMOTE-CIED trial (N=595), a Dutch multicenter prospective cohort study (N=413), and a Dutch multicenter feasibility study (N=41). All studies included an elaborative set of questionnaires to assess patient-reported outcomes, and information on clinical characteristics was collected from electronic patient records. The first part of this dissertation shows that comorbidities, stress, smoking, and heredity were most frequently mentioned by patients as heart failure causes. However, patients often failed to recognize physical risk factors and tended to underestimate their own risk. Furthermore, 20-25% of patients with heart failure and an ICD suffers from psychological distress (i.e. anxiety and/or depression) during the first weeks after implantation. Psychological characteristics – and not clinical characteristics – are associated with patients’ distress levels and heart failure perceptions, emphasizing the importance of early psychological screening to timely identify and treat patients at risk for distress. This part also shows that the driving restriction negatively influenced patients’ psychological wellbeing, with 28% of patients reporting to be non-compliant, and 49% reporting a decreased quality of life due to these restrictions. To support patients and partners in coping with heart failure and an ICD, we developed an ICD-specific psycho-education group program and tested its feasibility in six Dutch hospitals. A recruitment rate of 26% and drop-out rate of 7% shows indicates that this program can be implemented in Dutch clinical practice. The second part describes longitudinal data from the REMOTE-CIED trial, showing that remote patient monitoring leads to comparable levels of health status, ICD acceptance, and heart failure self-care behavior compared to regular in-hospital follow-up during the first two years after implantation. Both quantitative and qualitative data indicate that patients are generally satisfied with the Latitude® remote monitoring system from Boston Scientific. However, patients with a lower educational level, without work, and with chronic obstructive pulmonary disease more often prefer in-hospital follow-up. This emphasizes the importance to discuss patients’ preferences and needs with regard to ICD follow-up during in-clinic consultations in a shared-decision making process.

Published
2018

3. The patient perspective on remote monitoring of patients with an implantable cardioverter defibrillator : Narrative review and future directions

Author

Timmermans, I.A.L., Meine, M.M., Zitron, E., Widdershoven, J.W.M.G., Kimman, G., Prevot, S., Rauwolf, T., Anselme, F., Szendey, I., Romero Roldan, J., Mabo, P., Schaer, B., Denollet, J., Versteeg, H., and Medical and Clinical Psychology

Subjects
implantable cardioverter defibrillator, patient-reported outcomes, Journal Article, Review, remote patient monitoring, REMOTE-CIED, equipment and supplies, Cardiology and Cardiovascular Medicine
Abstract

Background: Studies have shown that remote patient monitoring (RPM) of implantable cardioverter defibrillators (ICDs) is at least comparable to in-clinic follow-up with regard to clinical outcomes and might be cost-effective, yet RPM is not standard clinical practice within Europe. Better insight into the patient perspective on RPM may aid in its acceptance, implementation, and reimbursement. This narrative review (1) summarizes existing evidence on the impact of RPM on patient-reported outcomes and (2) discusses future directions in examining the patient perspective. Methods and Results: Literature review indicated that only five randomized trials on RPM in ICD patients included patient-reported outcomes, with inconclusive results. Observational studies show a trend toward good patient satisfaction and acceptation of RPM. Yet, results should be interpreted with caution due to a number of limitations including a potential selection bias, use of generic/nonvalidated questionnaires, relatively short follow-up durations, and a lack of subgroup identification. Conclusion: Although RPM seems to be safe, effective, timely, and efficient, the patient perspective has received little attention so far. The scarce evidence on patient-reported outcomes in RPM studies seems to be positive, but future trials with a follow-up of ≥12 months and validated patient-reported outcome measures are needed. The REMOTE-CIED study from our group is the first prospective randomized controlled trial primarily designed to examine the patient perspective on RPM, and is powered to identify characteristics associated with RPM satisfaction and benefit. Results are expected in 2018 and will add valuable information to the current evidence.

Published
2017

7. Patient-reported causes of heart failure in a large European sample

Author

Timmermans, I.A.L., Denollet, J., Pedersen, Susanne S, Meine, Mathias, Versteeg, H., Timmermans, I.A.L., Denollet, J., Pedersen, Susanne S, Meine, Mathias, and Versteeg, H.

Abstract

Background: Patients diagnosed with chronic diseases develop perceptions about their disease and its causes, which may influence health behavior and emotional well-being. This is the first study to examine patient-reported causes and their correlates in patients with heart failure.Methods: European heart failure patients (N = 595) completed questionnaires, including the Brief Illness Perceptions Questionnaire. Using deductive thematic analysis, patient-reported causes were categorized into physical, natural, behavioral, psychosocial, supernatural and other. Clinical data were collected from medical records.Results: Patients who did not report any cause (11%) were on average lower educated and participated less often in cardiac rehabilitation. The majority of the remaining patients reported physical causes (46%, mainly comorbidities), followed by behavioral (38%, mainly smoking), psychosocial (35%, mainly (work-related) stress), and natural causes (32%, mainly heredity). There were socio-demographic, clinical and psychological group differences between the various categories, and large discrepancies between prevalence of physical risk factors according to medical records and patient-reported causes; e.g. 58% had hypertension, while only 5% reported this as a cause. Multivariable analyses indicated trends towards associations between physical causes and poor health status (Odds ratio (OR) = 1.41, 95% confidence interval (95% CI) = 0.95-2.09, p = 0.09), psychosocial causes and psychological distress (OR = 1.54, 95% CI = 0.94-2.51, p = 0.09), and behavioral causes and a less threatening view of heart failure (OR = 0.64, 95% CI = 0.40-1.01, p = 0.06).Conclusion: European patients most frequently reported comorbidities, smoking, stress, and heredity as heart failure causes, but their causal understanding may be limited. There were trends towards associations between patient-reported causes and health status, psychologica

Published
2018

8. Driving restrictions for Dutch patients with an implantable cardioverter defibrillator: Compliance and associated factors

Author

Jongejan, N., Timmermans, I.A.L., Elders, J., Meijer, K., Meine, M., Doevendans, P. A., Versteeg, H., Tuinenburg, A. E., Jongejan, N., Timmermans, I.A.L., Elders, J., Meijer, K., Meine, M., Doevendans, P. A., Versteeg, H., and Tuinenburg, A. E.

Abstract

Background: Dutch patients with an implantable cardioverter defibrillator (ICD) are restricted from driving for two months after implantation or shocks. This requires significant lifestyle adjustments and is one of the primary concerns of ICD patients. Previous studies indicated that compliance with the driving restrictions is poor, but insight in socio-demographic, clinical and psychological factors associated with compliance is limited. Hence, this study aimed to explore compliance with the driving restrictions and associated factors in a large sample of Dutch ICD patients. Method: Dutch ICD patients (N = 313) completed an elaborative set of questionnaires at time of implantation and at four months after implantation, assessing socio-demographic, psychological and driving-related characteristics. Clinical data were collected from the patients’ medical records. Results: A substantial subgroup (28%) of the patient sample (median age 64 (interquartile range = 55–71), 81% male) reported to have been noncompliant with the driving restrictions. Univariate analysis indicated that noncompliant patients more often considered refusing the ICD due to the restrictions, compared to compliant patients (19% versus 10%, p = 0.02). Multivariate analysis showed that the feeling of understanding the reason behind the driving restrictions was associated with better compliance (odds ratio = 2.16, 95% confidence interval 1.02–4.56, p = 0.04). No other socio-demographic, clinical, psychological or driving-related factors were associated with compliance. Conclusion: A large number of ICD patients does not comply with the driving restrictions after implantation. This study emphasised the importance of the patient’s feeling of understanding the reason behind the restrictions

Published
2018

11. Prevalence and risk markers of early psychological distress after icd implantation in the European remote-cied study cohort

Author

Versteeg, H., Timmermans, I.A.L., Meine, M., Zitron, E., Mabo, P., Denollet, J., Versteeg, H., Timmermans, I.A.L., Meine, M., Zitron, E., Mabo, P., and Denollet, J.

Abstract

Background Evidence on psychological distress in patients living with an implantable cardioverter defibrillator (ICD) is inconclusive. The current study is the first to examine the prevalence and risk markers of anxiety and/or depression in a large international cohort of European ICD patients with or without cardiac resynchronization therapy (CRT). Method Heart failure patients (N = 569) from France, Germany, Spain, Switzerland and the Netherlands participating in the REMOTE-CIED study completed a set of questionnaires 1–2 weeks post ICD-implantation, including the 7-item Generalized Anxiety Disorder scale and the 9-item Patient Health Questionnaire to assess anxiety and depressive symptoms, respectively. Patients' clinical data were obtained from their medical records. Results The prevalence of anxiety was 16% and that of depression 19%, with 25% of patients reporting one or both types of distress. Multivariable logistic regression analysis showed that age < 60 years (odds ratio (OR) = 2.5[95% confidence interval = 1.2–5.0]), having a threatening view of heart failure (OR = 4.7[2.7–8.2]), a high level of ICD-related concerns (OR = 2.9[1.7–5.1]), Type D personality (OR = 2.4[1.3–4.4]), poor patient-reported health status (OR = 2.2[1.3–3.9]) and receiving psychotropic medication (OR = 3.0[1.5–5.9]) were positively associated with distress, while attending cardiac rehabilitation (OR = 0.3[0.2–0.7]) was negatively associated with distress. Conclusions A significant subset of European ICD and CRT-defibrillator patients reports anxiety and/or depression in the first weeks post implantation. Patients' psychological characteristics, especially negative perceptions about their illness and treatment, were the strongest associates of distress. Timely identification of these patients is essential as they may benefit from psychological interventions and cardiac rehabilitation in terms of improved quality of life and prognosis.

Published
2017

Catalog

Books, media, physical & digital resources
See catalog results