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Cities are constantly changing to adapt to new societal and environmental challenges. Understanding their evolution is thus essential to make informed decisions about their future. To capture these changes, cities are increasingly offering digital 3D snapshots of their territory over time. However, existing tools to visualise these data typically represent the city at a specific point in time, limiting a comprehensive analysis of its evolution. In this paper, we propose a new method for simultaneously visualising different versions of the city in a 3D space. We integrate the different versions of the city along a new way of 3D timeline that can take different shapes depending on the needs of the user and the dataset being visualised. We propose four different shapes of timelines and three ways to place the versions along it. Our method places the versions such that there is no visual overlap for the user by varying the parameters of the timelines, and offer options to ease the understanding of the scene by changing the orientation or scale of the versions. We evaluate our method on different datasets to demonstrate the advantages and limitations of the different shapes of timeline and provide recommendations so as to which shape to chose. [ABSTRACT FROM AUTHOR]

This research note introduces the experience of using 'timelines' as a visual research method during online interviewing. It does so through a series of questions and answers that guide the reader through an exploration, understanding of and reflection on the method. This qualitative approach was used while conducting research on the influence that participation in a Reality TV show had on its finalists, and on the opportunities and life choices that were afforded to participants after the end of the show. The reader is encouraged to draw links between their own work as a qualitative researcher and the possibilities that this method can offer either in filling gaps or in expanding their current endeavour. Ultimately, the 'quality' of the answers we find in our qualitative work is illustrative of the way we choose to ask our questions. [ABSTRACT FROM AUTHOR]

Titanium carbide (Ti3C2Tx) MXene has attracted significant attention due to its exceptional properties and versatile solution processibility. However, MXene dispersions are prone to various degradation processes, leading to the formation of byproducts that negatively affect its morphological, electrical, and mechanical properties. Through the years, several methods have been developed to mitigate MXene degradation; however, divergent viewpoints on the understanding of degradation mechanisms are prevalent, hindering the development of versatile strategies in producing environmentally stable MXene dispersions. This review provides a chronological analysis of the research efforts aimed at unraveling the underlying mechanisms of MXene degradation and highlights strategies for circumventing this process. This review discusses apparent inconsistencies in experimental findings and theoretical models. These discrepancies prompt further investigation for a clearer understanding of the degradation process in MXene. This narrative allows readers to follow the evolution of dominant theories and disputes and to ultimately stimulate further investigation, aiming for a better understanding of this process. It is anticipated that identifying the fundamental factors affecting the oxidation of MXene dispersions will enable their full‐scale processing into higher‐order structures and practical devices with greater longevity and long‐term performance. [ABSTRACT FROM AUTHOR]

Researching well-being has gained popularity over the last decades however, research methodologies have employed mostly surveys, and the use of qualitative and visual methods is still scarce. This study discusses using timelines as a tool for researching the well-being of student teachers in two different cultural contexts. Research data includes researchers' notes as well as focus groups and students' notions of using timelines as a course assignment, analyzed using thematic analysis. This study shares our justification for using qualitative, visual methods to collect data related to well-being and evaluates the strengths and limitations of timelining as a tool to do this, from both the participants' and researchers' viewpoints. The study argues that timelines have the potential not only to support reflections on well-being but also to provide an approach to support it during teacher training and beyond. The use of timelines as tools to explore the non-linear and dynamic experiences of well-being during student teachers' teaching practice in Finland and England will be discussed and recommendations for the further development of this approach shared. [ABSTRACT FROM AUTHOR]

The construction industry has always been prone to uncertainties due to its dynamic nature, but the COVID-19 pandemic highlighted the need for a deeper understanding of its present challenges and their implications for the future of the industry. Despite numerous studies conducted on this topic, a comprehensive understanding of the factors stemming from COVID-19 that disrupted the industry is still lacking. This study aims to bridge that knowledge gap by identifying the challenges, categorizing them into four areas (cost overruns, schedule overruns, contractual implications, and health and safety issues), ranking them based on their frequency of occurrence in previous studies, and outlining management strategies to lessen their detrimental impacts on projects. A systematic literature review was conducted, and 284 publications were shortlisted for further review. The review revealed 26 challenges, of which shortage of labor, suspension or slowing of ongoing projects, force majeure confusion, and workplace safety concerns were among the most frequently cited, and offered strategies, such as workforce investment, supplier management, legal consultation, and transparent communication, for managing them. This research provides valuable insights for stakeholders and project managers in the construction sector that will help them comprehend and effectively manage the pandemic-induced challenges. [ABSTRACT FROM AUTHOR]

Cell line development (CLD) represents a complex but highly critical process during the development of a biological drug. To shed light on this crucial workflow, a team of BioPhorum members (authors) has developed and executed surveys focused on the activities and effort involved in a typical CLD campaign. An average of 27 members from different companies that participate in the BioPhorum CLD working group answered surveys covering three distinguishable stages of a standard CLD process: (1) Pre‐transfection, including vector design and construction; (2) Transfection, spanning the initial introduction of vector into cells and subsequent selection and analysis of the pools; and (3) Single Cell Cloning and Lead Clone Selection, comprising methods of isolating single cells and confirming clonal origin, subsequent expansion and screening processes, and methods for identifying and banking lead clones. The surveys were very extensive, including a total of 341 questions split between antibody and complex molecule CLD processes. In this survey review, the authors interpret and highlight responses for antibody development and, where relevant, contrast complex molecule development challenges to provide a comprehensive industry perspective on the typical time and effort required to develop a CHO production cell line. [ABSTRACT FROM AUTHOR]

Coastal areas are among the most productive areas in the world, ecologically as well as economically. Sea Surface Temperature (SST) has evolved as the major essential climate variable (ECV) and ocean variable (EOV) to monitor land–ocean interactions and oceanic warming trends. SST monitoring can be achieved by means of remote sensing. The current relatively coarse spatial resolution of established SST products limits their potential in small-scale, coastal zones. This study presents the first analysis of the TIMELINE 1 km SST product from AVHRR in four key European regions: The Northern and Baltic Sea, the Adriatic Sea, the Aegean Sea, and the Balearic Sea. The analysis of monthly anomaly trends showed high positive SST trends in all study areas, exceeding the global average SST warming. Seasonal variations reveal peak warming during the spring, early summer, and early autumn, suggesting a potential seasonal shift. The spatial analysis of the monthly anomaly trends revealed significantly higher trends at near-coast areas, which were especially distinct in the Mediterranean study areas. The clearest pattern was visible in the Adriatic Sea in March and May, where the SST trends at the coast were twice as high as that observed at a 40 km distance to the coast. To validate our findings, we compared the TIMELINE monthly anomaly time series with monthly anomalies derived from the Level 4 CCI SST anomaly product. The comparison showed an overall good accordance with correlation coefficients of R > 0.82 for the Mediterranean study areas and R = 0.77 for the North and Baltic Seas. This study highlights the potential of AVHRR Local Area Coverage (LAC) data with 1 km spatial resolution for mapping long-term SST trends in areas with high spatial SST variability, such as coastal regions. [ABSTRACT FROM AUTHOR]

ABSTRACT The objective was to explore publications on the effects of genotype × environment interaction (GEI) in livestock farming. The dataset used for this analysis came from the Web of Science (WOS) database, and the search was carried out from the first article identified in the WOS database until the search date (August 17, 2023). A set of minimum parameters was defined, and then the data was processed using the VOSviewer® software. To generate visual representations in VOSviewer, fractional counting was used, in which the contribution of each article is divided proportionally based on the number of co-authors. Consequently, if an article has three authors, the weight of each author is calculated as 1/3. Brazil and the United States lead research on GEI, while India, China, and Uruguay are emerging countries on the subject. The most cited journals on GEI include the Journal of Animal Science, Journal of Dairy Science, Animal, Livestock Science, Journal of Animal Breeding and Genetics, and Revista Brasileira de Zootecnia. In Brazil, the research groups are at the forefront of publications related to GEI. Ongoing climate changes over the years have likely led to further investigations into this matter. In the Brazilian context, research groups from the São Paulo State University (UNESP), College of Agricultural and Veterinary Sciences - Jaboticabal, and the Faculty of Veterinary Medicine and Animal Science at the University of São Paulo (FZEA/USP, Campus Pirassununga) have played a prominent role in advancing this area of study. Furthermore, our bibliometric analysis revealed future trends in GEI publications, including an increasing integration of genomic information into research.

Titanium carbide (Ti3C2Tx) MXene has attracted significant attention due to its exceptional properties and versatile solution processibility. However, MXene dispersions are prone to various degradation processes, leading to the formation of byproducts that negatively affect its morphological, electrical, and mechanical properties. Through the years, several methods have been developed to mitigate MXene degradation; however, divergent viewpoints on the understanding of degradation mechanisms are prevalent, hindering the development of versatile strategies in producing environmentally stable MXene dispersions. This review provides a chronological analysis of the research efforts aimed at unraveling the underlying mechanisms of MXene degradation and highlights strategies for circumventing this process. This review discusses apparent inconsistencies in experimental findings and theoretical models. These discrepancies prompt further investigation for a clearer understanding of the degradation process in MXene. This narrative allows readers to follow the evolution of dominant theories and disputes and to ultimately stimulate further investigation, aiming for a better understanding of this process. It is anticipated that identifying the fundamental factors affecting the oxidation of MXene dispersions will enable their full‐scale processing into higher‐order structures and practical devices with greater longevity and long‐term performance.

This article provides a timeline of the innovation, development, and clinical adoption of ureteroscopy, a procedure used for the treatment of kidney stones. The journey of flexible ureteroscopes began 70 years ago and has since seen rapid advancements in technology. These advancements include the development of tip-deflection mechanisms, working channels, and improvements in image quality. The article also discusses issues that have emerged, such as the susceptibility of the optics to laser energy and the management of irrigation and intrarenal pressure. Additionally, it highlights efforts to optimize ergonomics and the development of robotic systems for performing ureteroscopy. The article concludes by stating that the future holds further advancements in the field of ureteroscopy. [Extracted from the article]

This article compiles Colombia's participation in universal and international exhibitions to uncover a specific, fragmented, and lesser-known genealogy of national architectural history. By conceptualizing container and content as integral to the same narrative, this study analyzes forms, objects, and texts that reference the natural landscape of the homeland as an alternative approach to the predominant chronological, stylistic, or technological studies within this typology. The proposed categorization of these ephemeral showcases, based on enduring anthropological discourses on nature, offers an alternative pedagogical resource and dissemination method that encourages transdisciplinary and performative interpretations, opening new avenues of exploration within the discipline.

Since the 2011 Great East Japan Earthquake, 13 years have passed, and many areas have completed post-disaster reconstruction. Therefore, it is necessary to further summarise and analyse the experiences gained from this post-disaster reconstruction. This study conducted door-to-door interviews with residents of Ōtsuchi-chō, Iwate Prefecture, in the 13 years following the earthquake. It recorded the residents' perspectives on post-disaster reconstruction and its shortcomings. By collecting locally published materials like newspapers, and local government records and integrating them with interview records, the first "Great East Japan Earthquake Timeline" for Ōtsuchi-chō was compiled. We primarily divided this timeline into the following three phases: the disaster and early reconstruction period (2011), the mid-reconstruction period (2012–2015), and the late reconstruction period (2016–Present). This timeline has yielded the following results: firstly, some issues have arisen during this prolonged reconstruction process. For example, continuous relocation hinders community rebuilding, especially in the context of an ageing society. Secondly, the "Ōtsuchi-chō Reconstruction Timeline" was created, which can be used for post-disaster reconstruction in contemporary Japanese villages facing severe ageing. This timeline provides a clear understanding of how disaster-affected areas can rebuild housing and infrastructure, and recover economically. It offers guidance for the reconstruction of Japanese villages after a disaster. Therefore, post-disaster reconstruction in the region should accelerate infrastructure development and continuously listen to residents' voices, providing corresponding services to make reconstruction comprehensive and specific. At the same time, it also contributes to the post-disaster reconstruction of villages in other developed countries. [ABSTRACT FROM AUTHOR]

Copyright of Dearq is the property of Universidad de los Andes and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Identity changes over time through a series of external (Beauchamp &Thomas, 2009; Flores & Day, 2006; Sachs, 2005), but also of internal factors, such as emotions (Rodgers & Scott, 2008). The school placement is the pre-service teachers’ (PST) first year of confrontation with teaching and is characteristically an emotional experience (Zembylas, 2003). Several authors focus on the development of teachers at the beginning of their professional practice (Meijer, 2011). Moirs (1999) identifies five phases: anticipation, survival, disillusionment, rejuvenation, and reflection. The literature encourages us to continue investigating school placement contexts to better analyse and interpret the PSTs’ learning, thus improving teacher education (e.g., Gomes et al., 2023). This case study aimed to examine how PSTs perceive their learning trajectories by reflecting on the most memorable experiences of their school placement and associated emotions. In 2022/2023, three PSTs, two female and one male, aged between 22 and 24-year-olds, attending the 2nd year of the master's Teacher Education programme in Teaching Physical Education, filled out a Timeline (Adriansen, 2012) from September 2022 to March 2023, and attended a focus group for greater depth of their emotional/ learning trajectories. A content analysis (Patton, 2001) revealed that: In September, PST1 and PST2 began their journey with positive emotions (euphoria, enthusiasm, joy and hope) related to the first contact with the school and their classes –anticipation. PST3 reported negative emotions (anxiety, fear, concern) due to the volume and nature of the work he was expecting to deal with. During October, November and December, the PSTs’ 1 and 2 trajectories were marked by negative emotions (sadness, disappointment, frustration, lack of confidence, desire to give up), as they drew a descending curve - survival and disappointment, associated with a poor pedagogical relationship with students, the observation of classes, a bad relationship with the PST peers or the accumulation of work extra school. PST3 described a rising learning line, marked by positive emotions (confidence, pleasure, motivation), related to his success in teaching, the dynamisation of school activities and the good interaction with other teachers - rejuvenation until reaching a plateau of reflection between October and February. In January, February, and March, the PSTs’ 2 and 3 curves took a pointy downward before reaching a new anticipation phase (PST 002), subscribing to negative emotions (boredom, anxiety, sadness, and feelings of incompetence). The PST’s 1 learning curve assumed regular growth since November and December, marked by positive emotions (hope, confidence, motivation, joy), resulting from the success in implementing student-centred teaching strategies - new anticipation. At this point of their school placement, PST2 never reached an uplifting of her emotional/learning curve.

The outbreak of COVID-19 unleashed an unprecedented global pandemic, profoundly impacting lives and economies worldwide. Recognizing its severity, the World Health Organization (WHO) swiftly declared it a public health emergency of international concern. In response to this crisis, collaborative efforts have been underway to control the disease and minimize its health and socio-economic impacts worldwide. The COVID-19 epidemic curve holds vital insights into the history of exposure, transmission, testing, tracing, social distancing measures, community lockdowns, quarantine, isolation, and treatment, offering a comprehensive perspective on the nation’s response. One approach to gaining crucial insights is through meticulous analysis of available datasets, empowering us to effectively inform future strategies and responses. This study aims to provide descriptive data analytics of the COVID-19 pandemic in the Philippines, summarizing the country’s fight by visualizing epidemiological and mobility datasets, revisiting scientific papers and news articles, and creating a timeline of the critical issues faced during the pandemic. By leveraging these multifaceted analyses, policymakers and health authorities can make informed decisions to enhance preparedness, expand inter-agency cooperation, and effectively combat future public health crises. This study seeks to serve as a valuable resource, guiding nations worldwide in comprehending and responding to the challenges posed by COVID-19 and beyond.

Abstract Background NGAL and Cystatin C (CysC) as biomarkers for the early detection of AKI are subject to both pathophysiological, as well as patient related heterogeneity. The aim of this study was to investigate the timeline of plasma levels of NGAL and CysC during the first seven days of ICU admission in a mixed ICU population and to relate these to AKI severity during ICU stay. Via these means we aimed to bring clarity to the previously reported heterogeneity of these renal biomarkers. Methods Prospective Observation Cohort. Consecutive patients admitted to adult ICU at an academic hospital in the Netherlands between 18-02-2014 and 31-03-2014 were included. Urine output, serum creatinine, plasma NGAL and CysC were recorded during the first seven days of ICU admission. Biomarker expression was analyzed based on KDIGO score and time of AKI diagnosis. Results 335 patients were included, 110 met KDIGO criteria for AKI. NGAL and CysC plasma levels were higher in AKI patients compared to non-AKI, high variability in individual values resulted in 56% of AKI patients having a false negative, and 32% of non-AKI patients having a false positive. Individual biomarker levels were variable, and no pattern based on KDIGO score was observed. Conclusions Plasma NGAL and CysC as biomarkers for the early AKI detection may be subject to pathophysiological, and patient related heterogeneity. Further understanding of individual biomarker profiles may help in their application amongst mixed ICU populations. Trial Registration The need for informed consent was waived by the Institutional Ethical Review Board of the University Medical Center Groningen (METc 2013 − 174) by Prof. dr. W.A. Kamps on May 17th 2013.

The concept of the Metaverse has attracted considerable attention since 2021, primarily due to the rebranding of “Fakebook” to “Meta” and its promise of delivering a more immersive online experience. However, the origins of this term can be traced back to Neal Stephenson's sci-fi novel, “Snow Crash”, published in 1992. In the current study, an extensive articles review has been conducted, including academic sources, technology blogs, business reports, and social media posts. The main goal is to create a comprehensive timeline of the Metaverse and its underlying technologies. By categorizing 26 significant milestones into four distinct periods, the study introduces a framework called "4 Epochs of the Metaverse." The suggested framework challenges previously established linear timelines found in literature by identifying time periods that are based on content, rather than on chronological order. The findings emphasize that the Metaverse is not a new phenomenon, but, rather, a concept that has evolved over time since 1905 and can be classified under 4 dynamic periods, which are named Epochs. The study provides an in-depth description of the origins and evolution of the Metaverse, serving a dual purpose for researchers and practitioners: it provides insights into the transformative potential and future possibilities of the metaverse, while it lays the groundwork for further exploration and innovation in this phygital (physical + digital) environment.

We are all used to drawing straight lines to represent time, and above them, we plot historical events or physical or economic data. What to us is a self-evident convention, is however of an astonishingly recent date: it emerged only in the second half of the eighteenth century. To us, this late date seems paradoxical and cries out for an explanation. How else did earlier periods measure change, if not as a function of time? it will be argued that since Antiquity, time was taken to measure change, and change to occur in space. ‘Our’ idea of representing time as an independent dimension would have seemed aberrant. But then, a second issue arises. Did not medieval natural philosophers employ timelines, Oresme’s diagram of the mean speed theorem being the most famous case? However, as will be shown, our interpretation of his diagram is probably wrong. This insight, in turn, takes care of a third paradox, namely Galileo’s initial inability to represent the law of free fall correctly. This article will document that the timeline first emerged in the late sixteenth century in works on chronology, made its first appearance in physics in Galileo’s diagrams, and had its general breakthrough in the eighteenth century. [ABSTRACT FROM AUTHOR]

Background: NGAL and Cystatin C (CysC) as biomarkers for the early detection of AKI are subject to both pathophysiological, as well as patient related heterogeneity. The aim of this study was to investigate the timeline of plasma levels of NGAL and CysC during the first seven days of ICU admission in a mixed ICU population and to relate these to AKI severity during ICU stay. Via these means we aimed to bring clarity to the previously reported heterogeneity of these renal biomarkers. Methods: Prospective Observation Cohort. Consecutive patients admitted to adult ICU at an academic hospital in the Netherlands between 18-02-2014 and 31-03-2014 were included. Urine output, serum creatinine, plasma NGAL and CysC were recorded during the first seven days of ICU admission. Biomarker expression was analyzed based on KDIGO score and time of AKI diagnosis. Results: 335 patients were included, 110 met KDIGO criteria for AKI. NGAL and CysC plasma levels were higher in AKI patients compared to non-AKI, high variability in individual values resulted in 56% of AKI patients having a false negative, and 32% of non-AKI patients having a false positive. Individual biomarker levels were variable, and no pattern based on KDIGO score was observed. Conclusions: Plasma NGAL and CysC as biomarkers for the early AKI detection may be subject to pathophysiological, and patient related heterogeneity. Further understanding of individual biomarker profiles may help in their application amongst mixed ICU populations. Trial Registration: The need for informed consent was waived by the Institutional Ethical Review Board of the University Medical Center Groningen (METc 2013 − 174) by Prof. dr. W.A. Kamps on May 17th 2013. [ABSTRACT FROM AUTHOR]

Rules regarding children out of wedlock in Indonesia are divided into three laws starting from the Marriage Law, the Presidential Instruction on KHI, and the Civil Code. Following the Constitutional Court Decision No.46/PUU-VII/2010 the rules regarding children out of wedlock in the Marriage Law have also undergone re-reading. Each legal regulation for children out of wedlock has different legal consequences, so it is interesting to study about the concept of children out in the timeline of civil law regulations in Indonesia. This paper aimsis to find out the concept of children out of wedlock in the timeline of legal regulations in Indonesia. This research uses normative legal research with a statutory approach. The results of this study stated that the regulation of children out of wedlock was accommodated after the recognition of the Civil Code in the Indonesian legal system. On January 2, 1974 the provision of children out of wedlock was regulated in Article 43 paragraph (1) of the Marriage Law, after the promulgation of the Presidential Instruction on KHI the provision of children out of wedlock was regulated in Article 100 of the Presidential Instruction on KHI where children out of wedlock only had civil rights with the mother and her mother’s family. And, Constitutional Court Decision No.46/PUU-VII/2010 makes children out of wedlock have civil rights with their mother and father as long as it can be proven by technology and science. [ABSTRACT FROM AUTHOR]

Copyright of Diálogo com a Economia Criativa is the property of Dialogo com a Economia Criativa and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Currently, no timeline of cell heterogeneity in thermally injured skin has been reported. In this study, we proposed an approach to deconvoluting cell type abundance and expression from skin bulk transcriptomics with cell type signature matrix constructed by combining independent normal skin and peripheral blood scRNA-seq datasets. Using CIBERSORTx group mode deconvolution, we identified perturbed cell type fractions and cell type-specific gene expression in three stages postthermal injury. We found an increase in cell proportions and cell type-specific gene expression perturbation of neutrophils, macrophages, and endothelial cells and a decrease in CD4+ T cells, keratinocytes, melanocyte, and fibroblast cells, and cell type-specific gene expression perturbation postburn injury. Keratinocyte, fibroblast, and macrophage up regulated genes were dynamically enriched in overlapping and distinct Gene Ontology biological processes including acute phase response, leukocyte migration, metabolic, morphogenesis, and development process. Down-regulated genes were enriched in Wnt signaling, mesenchymal cell differentiation, gland and axon development, epidermal morphogenesis, and fatty acid and glucose metabolic process. We noticed an increase in the expression of CCL7, CCL2, CCL20, CCR1, CCR5, CCXL8, CXCL2, CXCL3, MMP1, MMP8, MMP3, IL24, IL6, IL1B, IL18R1, and TGFBR1 and a decrease in expression of CCL27, CCR10, CCR6, CCR8, CXCL9, IL37, IL17, IL7, IL11R, IL17R, TGFBR3, FGFR1-4, and IGFR1 in keratinocytes and/or fibroblasts. The inferred timeline of wound healing and CC and CXC genes in keratinocyte was validated on independent dataset GSE174661 of purified keratinocytes. The timeline of different cell types postburn may facilitate therapeutic timing. [ABSTRACT FROM AUTHOR]

In addition to being heinous crimes, acts of terrorism are complex chronopolitical events. Perpetrators, victims, survivors, families, and authorities manage their relationship to the events by engaging with and giving shape to time, or, rather, to a plurality of times. To perform this time work, they avail themselves of different genres, which serve as chronopolitical tools. This article discusses three such genres: the manifesto, the timeline, and the memorial site. These genres belong not only to different phases of the terror attacks but also to different actors. They are used to shape temporal progression in ways that enable specific forms of action, survival, and memory. The article takes the 22 July 2011 attacks in Norway as an example to map and analyze the role of these chronopolitical genres in managing the multiple times of terror. [ABSTRACT FROM AUTHOR]

This article examines how Facebook's Feed, its dynamic user interface, incorporates and refashions the capacity to temporalize cultural material and experience that has classically been attributed to subjectivity. I problematize the ambiguous historicity of digital culture across the experience of the ordinary that it produces by arranging the subjective time and 'ruined' bits of cultural material into algorithmic timelines. Drawing on recent media theory, I underscore the irreducible alienness of algorithmic temporalizations, which undermine habitual normalization. I show subjectivity moves beyond identity and narrative closure through an unconscious affective investment in extremely popular algorithmic timelines. [ABSTRACT FROM AUTHOR]

Context & Focus: The field of existential research is gently growing, yet currently relies on methods rooted in other psychological approaches. In 2014, Deurzen introduced her innovative phenomenological research method entitled: Structural Existential Analysis (SEA). SEA is increasingly being used as a secondary layer of analysis within qualitative research, yet few have applied SEA as an outright method before now. This paper expands upon the original SEA foundations to provide a clear, empirically supported 8-step guide for the application of SEA as an outright research method. The researcher's personal existential journey and their subjective use of philosophical heuristic models are considered. Resources for immersion into global existential philosophies are provided, moving beyond the prevailing Eurocentric sources to enrich the depth of insights available within the researcher's project and wider disciplinary field. Conclusion: Structural Existential Analysis (SEA) can be used as a stand-alone method of analysis for qualitative research. Unparalleled by existing research methods, this step-by-step application of SEA enables researchers to achieve a level of existential depth throughout their research journey moving beyond the prevailing Eurocentric contributions, advocates the importance of the human behind the research, supports the researcher's creativity and intuition within the research process, and provides resources for personal reflexivity and self-development. Positioned towards novice and qualified researchers, this step-by-step guide offers a foundation for conducting ethical, empirically valid, and replicable lived-experience research. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Wildland Fire Science is the property of Journal of Wildland Fire Science Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In the article the development of thin shell construction theory is considered according to the contribution of researchers, chronology, including the most accurate and simplified solutions. The review part of the article consists only of those publications which are related to the development of shell theory. The statement is based on the works of famous Russian researchers (V. V. Novozhilov, A. I. Lurie, A. L. Goldenweiser, H. M. Mushtari, V. Z. Vlasov), who developed the specified theory the most. The paper also mentions the researchers who improved the theory, calculation methods in aspects of strength, sustainability and vibrations of thin elastic shell constructions. Separately the application of the models for ribbed shells constructions is shown. It is reporting the basic principles of nonlinear thin shell construction theory development, including the nonlinear relations for deformations. In the article it is shown that if median surface of the shell is referred to the orthogonal coordinate system, then the expressions for deformations, obtained by different authors, practically correspond. The case in which the median surface of the shell is referred to an oblique-angled coordinate system was developed by A. L. Goldenweiser. For static problem, the functional of the total potential energy of deformation, representing the difference between the potential energy and the work of external forces, is used. The equilibrium equations and natural boundary conditions are derived from the minimum condition of this functional. In case of dynamic problem, the functional of the total deformation energy of the shell is described in which it is necessary to consider the kinetic energy of shell deformation. It is necessary to underline that the condition for minimum of the specified functional lets to derive the movement equations and natural boundary and initial conditions. Also, in the article the results of contemporary research of thin shell theory are presented.

Amyotrophic Lateral Sclerosis (ALS) is an incurable disease characterized by relentlessly progressive degeneration of the corticomotor system. Cortical hyperexcitability has been identified as an early pre-symptomatic biomarker of ALS. This suggests that hyperexcitability occurs upstream in the ALS pathological cascade and may even be part of the mechanism that drives development of symptoms or loss of motor neurons in the spinal cord. However, many studies also indicate a loss to the synaptic machinery that mediates synaptic input which raises the question of which is the driver of disease, and which is a homeostatic response. Herein, we used an inducible mouse model of TDP-43 mediated ALS that permits for the construction of detailed phenotypic timelines. Our work comprehensively describes the relationship between intrinsic hyperexcitability and altered synaptic input onto motor cortical layer 5 pyramidal neurons over time. As a result, we have constructed the most complete timeline of electrophysiological changes following induction of TDP-43 dysfunction in the motor cortex. We report that intrinsic hyperexcitability of layer 5 pyramidal neurons precedes changes to excitatory synaptic connections, which manifest as an overall loss of inputs onto layer 5 pyramidal neurons. This finding highlights the importance of hyperexcitability as a primary mechanism of ALS and re-contextualizes synaptic changes as possibly representing secondary adaptive responses. Recognition of the relationship between intrinsic hyperexcitability and reduced excitatory synaptic input has important implications for the development of useful therapies against ALS. Novel strategies will need to be developed that target neuronal output by managing excitability against synapses separately. [ABSTRACT FROM AUTHOR]

This brief report aims to compare the performance of motor reproduction and timeline estimation tasks in two groups of children aged 5–6 and 7–8 years old. The study included 80 children and used a computer-based experiment with two sessions for each method. The findings suggest that motor reproduction and timeline estimation tasks differ in accuracy and variability, with timeline estimation yielding more accurate and less variable estimates. These differences between the two tasks are even more pronounced in younger children. The discussion highlights the importance of using the timeline estimation task for future research on children’s time perception. [ABSTRACT FROM AUTHOR]

Political institutions and parties define the set of choices faced by voters, and structure the evolution of electoral preferences over the election cycle. While previous research examines the characteristics of institutions, here we consider the influence of political parties. We theorize ways in which they matter to the formation of electoral preferences over the election timeline, and also how these relate to institutional features. Our analysis simultaneously assesses the influence of different system‐ and party‐level variables on the dynamic structure of voters' preferences in legislative elections using a dataset of 27,357 vote intention polls in 26 countries since 1942, covering 231 discrete electoral cycles and encompassing 208 political parties. The results indicate that electoral institutions and parties are both important, but the characteristics of parties matter most of all, and effectively mediate institutional influences. These results have implications for the effects of election campaigns, the prediction of election outcomes, and party behavior itself. [ABSTRACT FROM AUTHOR]

Objective: The INTERMACS Events data set contains an expansive collection of temporal evidence of the course of adverse events (AEs) of >15 000 patients that have received a left ventricular assist device (LVAD). The chronology of AEs may contain insightful information of the "AE journeys" of LVAD patients. The purpose of this study is to investigate the timelines of AEs within the INTERMACS database. Methods: Descriptive statistics were applied to 86 912 recorded AEs of 15 820 patients with a continuous flow‐LVAD between 2008 to 2016, extracted from INTERMACS registry. The characteristics of the timelines of AE journeys were investigated by posing six descriptive research questions. Results: The analysis revealed several time‐related characteristics and patterns of the AE journey after LVAD including the most common time of occurrences of AEs after surgery, duration of AEs journeys, the time of first and last AEs, and the time gaps between AEs. Conclusion: The INTERMACS Event dataset is a valuable resource for research about the timeline of AE journeys of patients who received an LVAD. It is necessary for future studies to first explore and consider the time‐related characteristics of the data set such as diversity and sparsity to effectively choose an appropriate scope of time and time granularity and to acknowledge potential challenges. [ABSTRACT FROM AUTHOR]

A large concentration of ore deposits (i.e., tungsten, tin, lithium, beryllium, lead, zinc, silver, antimony and gold) related to metamorphism and hydrothermal activity of granite developed in the Himalayas and are located in the southern part of the Qinghai‐Tibet Plateau. As one of the newest and largest examples in the world of continental–continental collisional orogenic belts, the Himalayas are optimal for studying the coupling of continental collisions with metamorphic, tectonic, magmatic events and ore resources. Although considerable research has been conducted in the Himalayas, the timing of various geological processes remains debated, which limits the understanding of the genesis of ore deposits. To better understand the influence of orogeny on the metallogenic process, this study comprehensively presents the time of activity of the above‐mentioned four Cenozoic geological processes in the Himalayas. This contribution focuses on the context of the timeline to determine the internal connections and discusses the interrelationships of the geological processes. This study argues that Cenozoic lower crust–mantle interactions deep within the Indian continental plate below the Himalayas controlled the tectonics, metamorphism, magmatism and mineralization in the middle–upper crust. Cenozoic magmatic rocks in the upper crust are the direct results of the main‐collisional and post‐collisional stages of the Indian and Eurasian continental blocks. Intense collisional shearing and metamorphism during the Eocene formed the Himalayan fault–fold Belt and orogenic gold deposits. The break‐off, detachment and slab tearing of the Indian lithosphere during the Miocene led to the extensional structure of the middle–upper crust. There is a close coupling relationship between the exhumation of the middle–lower crust and the formation of large‐scale leucogranites during the Miocene in the upper crust, which provides the geological context for the main metallogenic period during which tungsten, tin, lithium, beryllium, lead, zinc, silver, antimony and gold ore widely developed. With technological advancements, the analytical accuracy of geological ages has gradually improved. In the future, research on the temporal constraints of important geological activities should be strengthened, and then a comprehensive evolutionary model of multiple spheres of geological processes in the Himalayas should be established. [ABSTRACT FROM AUTHOR]

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The influence of joint motion on punch efficiency before impact is still understudied. The same applies to the relationship between the kinematic and temporal parameters of a reverse punch (RP) that determines a score. Therefore, the aim of this study was to investigate if the exclusion or inclusion of body segments affects the acceleration, velocity, rotation angle, and timeline of execution, and to examine the correlation between these quantities. Seven elite male competitors—senior European and World Championship medalists—participated in the in-field testing. Quantities were acquired in the developmental phase of RP through three modalities of execution. Synchronized real-time data were obtained using combined multimodal sensors and camera fusion. The main findings of the study have highlighted the significant differences in the temporal and kinematic variables of RP that arise from the modality of execution. Large and medium correlation coefficients were obtained between the examined variables of body and hand. In conclusion, the results show that measured parameters are affected by segmental body activation. Moreover, their interdependence influences punch execution. The presented interdisciplinary approach provides insightful feedback for: (i) development of reliable and easy-to-use technical solutions in combat sports monitoring; and (ii) improvements in karate training. [ABSTRACT FROM AUTHOR]

American Oystercatcher (Haematopus palliatus) began relocating to noncoastal and atypical habitats decades ago potentially due to changing environmental factors. Historic literature does not address a route or progression timeline of species ingress to Chesapeake Bay. This study uses 286 Chesapeake Bay occurrence records to approximate the route, timeline of scout exploration, and nesting pioneer ingress, plus updating the species status and range last published in 1979. The records indicate relocating coastal oystercatchers entered through mouth of the Bay shortly after middle of the 20th century with the first scout being found in 1964 at Hampton from where exploration north reached Baltimore 23 years later. Records note the first nesting pioneers in 1976 on a remote island in Pocomoke Sound followed in 1977 by a pair on an uninhabited island in Tar Bay. Pocomoke Sound, Tangier Sound, and Tar Bay archipelagos form a nearly 70 km (43 mi) long contiguous chain of mostly uninhabited islands where pioneer ingress appeared to focus in the latter half of the 1970s and early 1980s before radiating in southwest directions during the 1980-1990s to areas scouted in the 1960s. Ingress pioneer activity remained in the lower half of Chesapeake Bay for several years before appearing north at Poplar Island in 2004. [ABSTRACT FROM AUTHOR]

Fellowship recruitment and retention of a skilled workforce is one of the biggest challenges that not only cytopathology is facing but that the field of pathology in general is being confronted with. There have long been issues with the fellowship recruitment process for both applicants and fellowship directors, including pressure to move the application process earlier and earlier and frustrations stemming from applicants needing to determine different individual timelines and program requirements. The unified timeline for fellowship recruitment was established as an attempt to standardize the recruitment process and to address the key issues of the push for earlier and earlier decision-making, which placed significant anxiety on trainees, as well as the burden on programs of more unexpected openings. While institution of the unified timeline has had many successes, there have been problems as well. Here, we discuss the multifaceted and intertwined factors that affect fellowship recruitment with a review of the historical context and the current setting and with an eye towards future directions. In the end, the issues we are currently facing are complex and there is likely no perfect solution to fixing an inherently broken system. However, the ultimate goal should be in better supporting our trainees' development and promoting a more fair and equitable recruitment process. Only by working together can we optimize the process for both applicants and programs alike. • The unified timeline for fellowship recruitment was an attempt to add more standardization to the recruitment process and to address some of the key issues including the push for earlier and earlier decision-making, which placed significant anxiety on residents, as well as the burden of more unexpected openings on programs. • The unified timeline has had many successes, but there have been issues as well; these issues reflect a complex interplay of different underlying issues that are plaguing not only the field of cytopathology but the field of pathology in general. • We herein discuss the issues complicating fellowship recruitment currently. We review the historical setting in order to add context to the current climate. We also discuss possibilities going forward. [ABSTRACT FROM AUTHOR]

Since the dawn of the digital world, people have been exploring ways to convert physical products into digital ones. At the moment there are few studies on the development and monetization of digital content. A problematic issue is the search for the most effective implementation of content on the distribution platform in order to obtain maximum economic benefits from it, provided that the main way to attract the target audience is through a social nerwork. This research is of a scientific and practical nature and aims to study the most effective ways to implement digital content, search for optimal management methods on the distribution platform, as well as study and analyze all the nuances of working on the Gumroad platform. Based on the developed criteria and the study of the possibilities of digital platforms, it was decided to manage the implementation of digital art content on this platform. Using the example of the presented project, the process of implementing digital art content from the first sales to stable income was considered. The target audience, its needs and features are considered and studied, as well as the most effective channels of implementation are analyzed. The features that affect demand are identified and analyzed.

Purpose:: Although several factors related to the concomitant meniscal injury at anterior cruciate ligament reconstruction (ACL-R) have been investigated in a general population, few studies have identified the risk factors of meniscal tear severity in young patients in which the majority of ACL tears occur. The purpose of this study was to analyze the associated factors with meniscal injury and irreparable meniscal tear and the timeline for medial meniscal injury at ACL-R in young patients. Methods:: A retrospective analysis of young patients (13 to 29 years of age) who underwent ACL-R by a single surgeon from 2005 to 2017 was conducted. Predictor variables (age, sex,body mass index [BMI], time from injury to surgery [TS], and pre-injury Tegner activity level) for meniscal injury and irreparable meniscal tear were analyzed with multivariate logistic Results:: Four hundred and seventy-three consecutive patients with an average of 31.2 months post-operative follow-up were enrolled in this study. The risk factors for medial meniscus injury were TS (

Mosquitoes are extremely important vectors that transmit zoonotic West Nile virus (WNV) globally, resulting in significant outbreaks in birds, humans, and mammals. The abundance of mosquito vectors combined with the migratory flying behaviour of wild birds across the globe has exacerbated the dynamics of WNV infection. Depth understanding of the WNV infection requires a comprehensive understanding of the character of the vector in terms of their taxonomy, morphology, biology, behaviours, preferences, and factors that promote their breeding. Most susceptible animals and humans may experience serious neurological illnesses such as encephalitis. Little is known about the susceptibility of mosquitoes to WNV infection. This review provides insightful knowledge about the characteristics of mosquitoes that carry WNV and their susceptibility to WNV infection. The context of mosquito’s involvement in WNV transmission is demonstrated through space and time from the 1950’s until to date. The historical timeline of WNV transmission strength was significantly intensified via the complex interactions between vector, virus, and environment. Such knowledge will provide valuable insights into vector control intervention mitigation strategies, especially in tropical climate countries like Malaysia. [ABSTRACT FROM AUTHOR]