Search

Your search keyword '"Tillmann, Vallo"' showing total 468 results
Start Over Author "Tillmann, Vallo"
468 results on '"Tillmann, Vallo"'

1. Associations of Serum Irisin and Fibroblast Growth Factor-21 Levels With Bone Mineral Characteristics in Eumenorrheic Adolescent Athletes With Different Training Activity Patterns.

Author

Jürimäe, Jaak, Remmel, Liina, Tamm, Anna-Liisa, Purge, Priit, Maasalu, Katre, and Tillmann, Vallo

Subjects
GYMNASTICS, PHOTON absorptiometry, OSTEOCALCIN, BONE density, RESEARCH funding, FOOD consumption, PHYSICAL training & conditioning, DESCRIPTIVE statistics, EXERCISE intensity, SERUM, FIBRONECTINS, MENSTRUAL cycle, FIBROBLAST growth factors, SWIMMING, LUMBAR vertebrae, COLLAGEN, SPINE, COMPARATIVE studies, BIOMARKERS, DIET, MYOKINES
Abstract

Purpose: To describe serum irisin and fibroblast growth factor-21 (FGF-21) concentrations in healthy female adolescents with different training activity patterns and their associations with bone mineral properties and metabolic markers. Methods: A total of 62 adolescent girls aged 14–18 years were recruited: 22 rhythmic gymnasts, 20 swimmers, and 20 untrained controls. Bone mineral characteristics by dual-energy X-ray absorptiometry, daily energy intake by dietary recall, serum irisin, FGF-21, undercarboxylated osteocalcin, and C-terminal telopeptide of type I collagen were measured in all girls. Results: Whole body and lumbar spine areal bone mineral density and lumbar spine bone mineral content were higher in the rhythmic gymnasts group compared with swimmers and untrained controls groups (P <.05). Serum irisin, FGF-21, undercarboxylated osteocalcin, and C-terminal telopeptide of type I collagen levels were not significantly different between the groups. In the rhythmic gymnasts group, serum FGF-21 concentration was positively correlated with lumbar spine areal bone mineral density independently of confounding factors (r =.51; P =.027). Conclusions: Serum irisin and FGF-21 levels were not different between adolescent eumenorrheic girls with different training activity patterns. FGF-21 was positively associated with lumbar spine areal bone mineral density, which predominantly consists of trabecular bone in adolescent rhythmic gymnasts. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

8. Arterial Structure in 18-Year-Old Males Is Dependent on Physical Activity at 12 Years and Cumulative Cardiorespiratory Fitness From Puberty to Late Adolescence.

Author

Kraav, Juta, Tamme, Reeli, Remmel, Liina, Mäestu, Evelin, Zagura, Maksim, Jürimäe, Jaak, and Tillmann, Vallo

Subjects
CAROTID artery, BODY composition, BLOOD pressure, CAROTID intima-media thickness, CARDIOPULMONARY fitness, TIME, MULTIPLE regression analysis, ACCELEROMETERS, PUBERTY, PHYSICAL activity, PULSE wave analysis, RESEARCH funding, HEART beat, BODY mass index, EMOTION regulation, SMOKING, ADOLESCENCE
Abstract

Purpose: To evaluate the long-term effect of body composition, physical activity, and cardiorespiratory fitness (CRF) from puberty on arterial health in late adolescent males. Methods: The cumulative burden of physical activity (measured with accelerometer), CRF (VO2peak0.82), and body composition (body mass index, fat mass, and fat percentage) from puberty to late adolescence (sum of 4 time points from 12 to 18 y) was assessed in 102 males. Additional analysis on the first (T1) and last (T4) time points was performed. Intima-media thickness (IMT), carotid-femoral pulse wave velocity, and augmentation index adjusted to heart rate of 75 beats per minute (bpm) as dependent variables were measured at T4 and analyzed in multivariable regression models adjusted for known risk factors including maturation, blood pressure, and smoking habits. Results: T1 and cumulative body composition measures were independently associated with IMT, while cumulative (β = −0.011, P =.036) and T4 (β = −0.0.031, P =.001) CRF revealed independent associations with IMT. Individuals with moderate to vigorous physical activity >60 minutes per day at T1 showed relationship (β = −1.091, P =.026) with IMT independently of late adolescent physical activity. No significant relationship was present for arterial function. Conclusion: Arterial structure in adolescent males is associated with physical activity at 12 years while relationship with CRF can be seen in late adolescence and cumulatively from puberty to late adolescence. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

9. Impaired protein hydroxylase activity causes replication stress and developmental abnormalities in humans

Author

Fletcher, Sally C., Hall, Charlotte, Kennedy, Tristan J., Pajusalu, Sander, Wojcik, Monica H., Boora, Uncaar, Li, Chan, Oja, Kaisa Teele, Hendrix, Eline, Westrip, Christian A.E., Andrijes, Regina, Piasecka, Sonia K., Singh, Mansi, Asrag, Mohammed E. El-, Ptasinska, Anetta, Tillmann, Vallo, Higgs, Martin R., Carere, Deanna A., Beggs, Andrew D., Pappas, John, Rabin, Rachel, Smerdon, Stephen J., Stewart, Grant S., Ounap, Katrin, and Coleman, Mathew L.

Subjects
Hydroxylases -- Analysis, Embryonic development -- Analysis, Proteins -- Analysis, Health care industry
Abstract

Although protein hydroxylation is a relatively poorly characterized posttranslational modification, it has received significant recent attention following seminal work uncovering its role in oxygen sensing and hypoxia biology. Although the fundamental importance of protein hydroxylases in biology is becoming clear, the biochemical targets and cellular functions often remain enigmatic. JMJD5 is a 'JmjC-only' protein hydroxylase that is essential for murine embryonic development and viability. However, no germline variants in JmjC-only hydroxylases, including JMJD5, have yet been described that are associated with any human pathology. Here we demonstrate that biallelic germline JMJD5 pathogenic variants are deleterious to JMJD5 mRNA splicing, protein stability, and hydroxylase activity, resulting in a human developmental disorder characterized by severe failure to thrive, intellectual disability, and facial dysmorphism. We show that the underlying cellular phenotype is associated with increased DNA replication stress and that this is critically dependent on the protein hydroxylase activity of JMJD5. This work contributes to our growing understanding of the role and importance of protein hydroxylases in human development and disease., Introduction The enzymatic incorporation of a single oxygen atom into an amino acid side chain is a relatively poorly characterized but emerging posttranslational modification (PTM) (1). Seminal work on the [...]

Published
2023
Full Text
View/download PDF

15. Genomic variation and strain-specific functional adaptation in the human gut microbiome during early life

Author

Vatanen, Tommi, Plichta, Damian R., Somani, Juhi, Münch, Philipp C., Arthur, Timothy D., Hall, Andrew Brantley, Rudolf, Sabine, Oakeley, Edward J., Ke, Xiaobo, Young, Rachel A., Haiser, Henry J., Kolde, Raivo, Yassour, Moran, Luopajärvi, Kristiina, Siljander, Heli, Virtanen, Suvi M., Ilonen, Jorma, Uibo, Raivo, Tillmann, Vallo, Mokurov, Sergei, Dorshakova, Natalya, Porter, Jeffrey A., McHardy, Alice C., Lähdesmäki, Harri, Vlamakis, Hera, Huttenhower, Curtis, Knip, Mikael, and Xavier, Ramnik J.

Published
2019
Full Text
View/download PDF

21. Exploring the risk factors for differences in the cumulative incidence of coeliac disease in two neighboring countries: the prospective DIABIMMUNE study

Author

Knip, Mikael, Koski, Katriina, Koski, Matti, Härkönen, Taina, Siljander, Heli, Ryhänen, Samppa, Hämäläinen, Anu-Maaria, Ormisson, Anne, Peet, Aleksandr, Tillmann, Vallo, Ulich, Valentina, Kuzmicheva, Elena, Mokurov, Sergei, Markova, Svetlana, Pylova, Svetlana, Isakova, Marina, Shakurova, Elena, Petrov, Vladimir, Dorshakova, Natalya V., Karapetyan, Tatyana, Varlamova, Tatyana, Ilonen, Jorma, Kiviniemi, Minna, Alnek, Kristi, Janson, Helis, Uibo, Raivo, von Mutius, Erika, Weber, Juliane, Ahlfors, Helena, Kallionpää, Henna, Laajala, Essi, Lahesmaa, Riitta, Lähdesmäki, Harri, Moulder, Robert, Nieminen, Janne, Ruohtula, Terhi, Vaarala, Outi, Honkanen, Hanna, Hyöty, Heikki, Kondrashova, Anita, Oikarinen, Sami, Harmsen, Hermie J.M., De Goffau, Marcus C., Welling, Gjal, Alahuhta, Kirsi, Virtanen, Suvi M., Simre, Kärt, Uibo, Oivi, Kool, Pille, and Virtanen, Suvi

Published
2016
Full Text
View/download PDF

24. Tõenduspõhine lähenemine neonataalabi korraldusele Eestis

Author

Toome, Liis, Metsvaht, Tuuli, Einberg, Ülle, Tillmann, Vallo, Saik, Pille, Ilmoja, Mari-Liis, Eelmäe, Imbi, Laan, Mari, Pruunsild, Chris, and Varendi, Heili

Abstract

Peri- ja neonataalabi ravitulem sõltub riigi rikkuse ja sotsiaalse arengu ning meditsiinitehnoloogia kättesaadavuse ja meditsiinimeeskonna pädevuse kõrval peri- ja neonataalabi organisatoorsest korraldusest. Peri- ja neonatoloogia on meditsiini valdkond, kus planeerimisel, organisatsioonil ja keskuste vastastikusel seotusel on tugevaim mõju pakutava abi kvaliteedile. Artiklis on antud ülevaade Eesti peri- ja neonataalabi senistest ravitulemustest, tugevatest ja nõrkadest külgedest ning üldtunnustatud tõenduspõhistest tervishoiukorralduslikest põhimõtetest. Esitatud on artikli autorite vaated edasise peri- ja neonataalabi korralduse kohta Eestis., Eesti Arst, 2022: November

Published
2022
Full Text
View/download PDF

28. Standard of hygiene and immune adaptation in newborn infants

Author

Koski, Katriina, Koski, Matti, Ryhänen, Samppa, Siljander, Heli, Hämäläinen, Anu-Maaria, Ormisson, Anne, Peet, Aleksandr, Ulich, Valentina, Kuzmicheva, Elena, Mokurov, Sergei, Markova, Svetlana, Pylova, Svetlana, Isakova, Marina, Shakurova, Elena, Petrov, Vladimir, Karapetyan, Tatyana, Varlamova, Tatyana, Ilonen, Jorma, Kiviniemi, Minna, Alnek, Kristi, Janson, Helis, Uibo, Raivo, Salum, Tiit, von Mutius, Erika, Weber, Juliane, Ahlfors, Helena, Moulder, Robert, Nieminen, Janne, Ruohtula, Terhi, Vaarala, Outi, Honkanen, Hanna, Hyöty, Heikki, Kondrashova, Anita, Oikarinen, Sami, Harmsen, Hermie J.M., De Goffau, Marcus C., Welling, Gjalt, Alahuhta, Kirsi, Korhonen, Tuuli, Virtanen, Suvi M., Kallionpää, Henna, Laajala, Essi, Öling, Viveka, Härkönen, Taina, Tillmann, Vallo, Dorshakova, Natalya V., Lähdesmäki, Harri, Knip, Mikael, and Lahesmaa, Riitta

Published
2014
Full Text
View/download PDF

33. Publisher Correction: Genomic variation and strain-specific functional adaptation in the human gut microbiome during early life

Author

Vatanen, Tommi, Plichta, Damian R., Somani, Juhi, Münch, Philipp C., Arthur, Timothy D., Hall, Andrew Brantley, Rudolf, Sabine, Oakeley, Edward J., Ke, Xiaobo, Young, Rachel A., Haiser, Henry J., Kolde, Raivo, Yassour, Moran, Luopajärvi, Kristiina, Siljander, Heli, Virtanen, Suvi M., Ilonen, Jorma, Uibo, Raivo, Tillmann, Vallo, Mokurov, Sergei, Dorshakova, Natalya, Porter, Jeffrey A., McHardy, Alice C., Lähdesmäki, Harri, Vlamakis, Hera, Huttenhower, Curtis, Knip, Mikael, and Xavier, Ramnik J.

Published
2019
Full Text
View/download PDF

41. The Impact of Physical Activity on Serum Inflammatory Markers in Overweight Pubertal Boys: 24-Month Follow-Up Study.

Author

Remmel, Liina, Tillmann, Vallo, Mengel, Eva, Kool, Pille, Purge, Priit, Lätt, Evelin, and Jürimäe, Jaak

Subjects
CYTOKINES, INTERFERONS, INTERLEUKINS, LONGITUDINAL method, CHILDHOOD obesity, ACCELEROMETRY, PHYSICAL activity
Abstract

Purpose: To investigate the differences in the pattern of changes in serum inflammatory cytokines measured annually over a 24-month period, between less active and more active overweight boys. Participants/Methods: In total, 25 pubertal overweight boys were divided by their moderate to vigorous physical activity (MVPA) levels into 2 groups: less active group (LAG; n = 10; MVPA < 60 min/d) and more active group (MAG; n = 15; MVPA > 60 min/d). Physical activity was measured by 7-day accelerometry. Serum concentration of 13 inflammatory cytokines [interleukin (IL)-2, IL-4, IL-6, IL-8, IL-10, IL-1α, IL-1β, vascular endothelial growth factor, interferon-γ, tumor necrosis factor-α, monocyte chemotactic protein-1, epidermal growth factor, and C-reactive protein] was measured at baseline (T0), after 12 months (T1), and after 24 months (T2) from fasting blood samples. Results: Serum IL-6 level was significantly higher [LAG: 1.27 (0.86, 1.98) pg/mL; MAG: 0.80 (0.52, 0.84) pg/mL] at T0 and IL-8 level [LAG: 10.26 (8.80, 11.64) pg/mL; MAG: 7.42 (6.10, 9.54) pg/mL] at T2 in LAG compared with MAG. The changes over the study period varied between different inflammatory markers. None of the slopes of any measured markers were statistically different between the LAG and MAG, although the slopes of interferon-γ and IL-10 tended to be different between the groups. Conclusions: The pattern of changes over the study period varied between different inflammatory markers, but these changes were not different between the MVPA groups. More longitudinal studies are needed to investigate whether IL-6, IL-8, IL-10, and interferon-γ would be the choice of inflammatory markers to study the associations between obesity and physical activity in future. [ABSTRACT FROM AUTHOR]

Published
2018
Full Text
View/download PDF

47. Serum sclerostin concentration is associated with specific adipose, muscle and bone tissue markers in lean adolescent females with increased physical activity

Author

Jürimäe, Jaak, primary, Karvelyte, Vita, additional, Remmel, Liina, additional, Tamm, Anna-Liisa, additional, Purge, Priit, additional, Gruodyte-Raciene, Rita, additional, Kamandulis, Sigitas, additional, Maasalu, Katre, additional, Gracia-Marco, Luis, additional, and Tillmann, Vallo, additional

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results