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Otizm Spektrum Bozukluğu OSB çocukluk döneminde başlangıç gösteren, iletişimde büyük sorunlara yol açan ve bireyin işlevselliğini ve yaşam kalitesini belirgin şekilde etkileyen bir nörogelişimsel rahatsızlıktır. Tik bozuklukları, dikkat eksikliği hiperaktivite bozukluğu gibi birçok psikiyatrik hastalıkla komorbidite gösterebilmektedir. Atipikantipsikotikler OSB olgularında irritabilite ve eşlik eden psikiyatrik rahatsızlıkların tedavisinde sıklıkla kullanılmaktadır. Bu ilaçlardan aripiprazol son yıllarda etki profili nedeniyle oldukça popülerlik kazanmıştır. Psikiyatrik bozuklukların tedavisinde düşük doz aripiprazolünmonoterapi olarak etkinliği dikkat çekicidir. Bu olgu sunumunda ASD ve Tourette Sendromlu otistik çocuğun tedavisinde düşük doz aripiprazolmonoterapisinin etkinliğini sunacağız

Copyright of Turkish Journal of Child & Adolescent Mental Health / Çocuk ve Gençlik Ruh Sagligi Dergisi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: In this study, it is aimed to do a cross-sectional evaluation of treatment preferences in tic disorders in a clinical sample. Method: The hospital records of cases diagnosed with tic disorders who were admitted to our clinic between May 2013 and June 2014 were retrospectively reviewed. SPSS 17.0 program was used to evaluate the data. The level of significance was accepted as p <0.05 Results: Our sample was consisted of 92 children with a mean age of 10.8±3.2 years. Distribution of diagnosis of tic disorders were as follows: Tic Disorders (TD)-Not Otherwise Specified (46.7%), Tourette Syndrome (23.9%), Chronic Motor TD (20.7%), and Transient TD (8.7%).45.7% of cases had at least one comorbid psychiatric disorder. While most frequently preferred class of psychotropic medications were atypical antipsychotics (33.7%), most frequently prescribed psychotropic medications were aripiprazole, atomoxetine, risperidone, selective serotonin re-uptake inhibitors (SSRIs), methylphenidate, hydroxyzine and haloperidol, respectively by psychiatrists. Predictors of medication use were found to be being an adolescent and having chronic tic disorder (TS or chronic motor TD). Discussion: The frequent preference of atypical antipsychotics in the treatment of tic disorders is similar with some treatment guidelines. The use of medications used for treatment of attention deficit hyperactivity disorder and SSRIs can be explained by treatment of comorbid conditions. Our study is one of the first studies on pharmacotherapy applications in tic disorders from our country. In order to generalize our findings, prospectively planned, multicentered studies with larger samples are needed in children with tic disorders. [ABSTRACT FROM AUTHOR]

Purpose: In this study, we aimed to investigate the sociodemographic and clinical characteristics of children and adolescents diagnosed with tic disorders. Materials and Methods: The study population included 187 children with tic disorders, aged between 4 and 18 years. The data were obtained by using Yale Global Tic Severity Scale (YGTSS), Screen for Child Anxiety and Related Disorders, Schedule for Affective Disorders and Schizophrenia for School Age Children-Present and Lifetime Version (K-SADS-PL). The demographic information, history of familial diseases were recorded. Results: The study included 37 girls (mean 10.9 ± 2.5 years) and 150 boys (mean 10.9 ± 2.7 years) with a mean age of 10.9 ± 2.6 years. Of all cases, 135 were classified as Tourette Syndrome (n=135; 72,2%), 50 as motor tics (n=50; 26,7 %) and 2 as others tic disorders (n=2; 1,1%) according to the diagnostic tic disorders subtype. There was no significant difference between the two groups in terms of mean age and first symptom age according to the subtype of tic disorder. In 9 1% of the cases, the age of onset of tics was 12 years or younger. The rate of having at least one comorbidity, mean number of comorbidities and comorbid ADHD rates were significantly higher among boys than girls. The most common comorbid diagnoses were ADHD (n=142, 75.9%), OCD (n= 08, 57.8%) and anxiety disorder (n=57, 30.4%). Conclusion: In our study, male cases, early onset and multiple comorbid diagnoses were found to be significantly higher in childhood tic disorders. [ABSTRACT FROM AUTHOR]

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that begins in childhood, causes major problems in communication and significantly affects daily functioning and quality of life of the individual. Many psychiatric disorders such as tic disorders, attention deficit hyperactivity disorder may ve comorbid with ASD. Atypical antipsychotics are frequently using in the treatment of irritability and comorbid psychiatric disorders in individuals with ASD. Aripiprazole popularity has raised in recent years due to its efficacy profile. Effectiveness of low dose aripiprazole as monotherapy in the treatment of psychiatric disorders are remarkable. In this case report, we will present effectiveness of low dose aripiprazole monotheraphy in the treatment of autistic child with ASD and Tourette Syndrome. [ABSTRACT FROM AUTHOR]

In recent years, PANDAS has been frequently described as a type of childhood neuropsychiatric disorder. Obsessive- compulsive symptoms, tics and other neuropsychiatric changes may occur after group A-beta hemolytic streptococcal (GABHS) infection. Especially difficulties with diagnose and perplexity about treatment may be occured. In this paper, approach for diagnose and treatment are discussed on a case basis. [ABSTRACT FROM AUTHOR]

Copyright of Turkish Journal of Psychiatry is the property of Turk Psikiyatri Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Tic disorders which involve sudden and repetitive movements, gestures, or vocalizations form a spectrum ranging from simple transient tic disorders to more severe tic disorders that may cause significant impairment in psychosocial development, self esteem, family and social relationships, or academic/career performance. Around 6-20% of children experience simple transient tic disorder, while the prevalence of Tourette Syndrome (TS), a more severe tic disorder, is 5 to 6 cases in 1000 children. The severity and frequency of tics may change over time: usually peaking at the beginning of the second decade of life and diminishing towards the end of puberty. Psychosocial stressors, genetic and epigenetic factors and the interactions between these factors are involved in the etiology of tic disorders. In recent years, with the understanding of the suitability of TS as a model in investigating the interaction between genetic and environmental risk factors, increasing number of researches have been conducted in that direction. [ABSTRACT FROM AUTHOR]

Patients with attention deficit and hyperactivity disorder (ADHD) are at increased risk for Tourette's Disorder and other tic disorders. The cornerstone treatment for ADHD include the psychostimulants, such as methylphenidate. It is known that, psychostimulant use can increase existing tics or cause new tics. The selective norepinephrine reuptake inhibitor, atomoxetine, has been proposed to be an alternative medication for patients with ADHD and a comorbid tic disorder. However, there are case studies in the literature describing onset or increase of tics following treatment with atomoxetine. In this report, we discuss a clinical case that developed motor tics during atomoxetine treatment. [ABSTRACT FROM AUTHOR]