Search

Your search keyword '"Tichelli A"' showing total 2,342 results
Start Over Author "Tichelli A"
2,342 results on '"Tichelli A"'

2. PB2574: HEMOPHAGOCYTIC SYNDROME IN ADULTS - REAL-WORLD DATA ON MORTALITY FROM A TERTIARY REFERENCE CENTER

Author

Tatiana Wojtovicova, Drahomir Aujesky, Stephan Jakob, Nicolas Bonadies, Hansjakob Furrer, Urban Novak, Thomas Pabst, Britta Maurer, Burkhard Möller, Roman Christian Abegglen, Aristomenis Exadaktylos, Annalisa Berzigotti, Yara Banz, Vera Ulrike Bacher, Sacha S. Zeerleder, Joerg C. Schefold, André Tichelli, Anne Angelillo-Scherrer, and Alicia Rovó

Subjects
Diseases of the blood and blood-forming organs, RC633-647.5
Published
2023
Full Text
View/download PDF

3. Translational longevity medicine: a Swiss perspective in an ageing country

Author

Marco M. Ruckstuhl, Evelyne Bischof, Dana Blatch, Aliki Buhayer, Jörg Goldhahn, Edouard Battegay, Andre Tichelli, and Collin Y. Ewald

Subjects
Medicine
Abstract

Breakthroughs in medical research in the last century have led to a significant extension of the human lifespan, resulting in a shift towards an elderly population worldwide. Due to the ongoing progress of global development towards elevated standards of living, this study specifically examines Switzerland as a representative nation to explore the socioeconomic and healthcare ramifications associated with an ageing population, thereby highlighting the tangible impact experienced in this context. Beyond the exhaustion of pension funds and medical budgets, by reviewing the literature and analysing publicly available data, we observe a “Swiss Japanification”. Old age is associated with late-life comorbidities and an increasing proportion of time spent in poor health. To address these problems, a paradigm shift in medical practice is needed to improve health rather than respond to existing diseases. Basic ageing research is gaining momentum to be translated into therapeutic interventions and provides machine learning tools driving longevity medicine. We propose that research focus on closing the translational gap between the molecular mechanisms of ageing and a more prevention-based medicine, which would help people age better and prevent late-life chronic diseases.

Published
2023
Full Text
View/download PDF

4. Male-specific late effects in adult hematopoietic cell transplantation recipients: a systematic review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and Transplant Complications Working Party of the European Society of Blood and Marrow Transplantation

Author

Phelan, Rachel, Im, Annie, Hunter, Rebecca L., Inamoto, Yoshihiro, Lupo-Stanghellini, Maria Teresa, Rovo, Alicia, Badawy, Sherif M., Burns, Linda, Eissa, Hesham, Murthy, Hemant S., Prasad, Pinki, Sharma, Akshay, Suelzer, Elizabeth, Agrawal, Vaibhav, Aljurf, Mahmoud, Baker, Karen, Basak, Grzegorz W., Buchbinder, David, DeFilipp, Zachariah, Grkovic, Lana Desnica, Dias, Ajoy, Einsele, Hermann, Eisenberg, Michael L., Epperla, Narendranath, Farhadfar, Nosha, Flatau, Arthur, Gale, Robert Peter, Greinix, Hildegard, Hamilton, Betty K., Hashmi, Shahrukh, Hematti, Peiman, Jamani, Kareem, Maharaj, Dipnarine, Murray, John, Naik, Seema, Nathan, Sunita, Pavletic, Steven, Peric, Zinaida, Pulanic, Drazen, Ross, Richard, Salonia, Andrea, Sanchez-Ortega, Isabel, Savani, Bipin N., Schechter, Tal, Shah, Ami J., Smith, Stephanie M., Snowden, John A., Steinberg, Amir, Tremblay, Douglas, Vij, Sarah C., Walker, Lauren, Wolff, Daniel, Yared, Jean A., Schoemans, Hélène, and Tichelli, André

Published
2022
Full Text
View/download PDF

5. Metabolic syndrome and cardiovascular disease after haematopoietic cell transplantation (HCT) in adults: an EBMT cross-sectional non-interventional study

Author

Greenfield, D. M., Salooja, N., Peczynski, C., van der Werf, S., Schoemans, H., Hill, K., Cortelezzi, A., Lupo-Stangellini, M., Özkurt, Z. N., Arat, M., Metzner, B., Turlure, P., Rovo, A., Socié, G., Mohty, M., Nagler, A., Kröger, N., Dreger, P., Labopin, M., Han, T. S., Tichelli, A., Duarte, R., Basak, G., and Snowden, J. A.

Published
2021
Full Text
View/download PDF

7. Systematic Reviews in Hematopoietic Cell Transplantation and Cellular Therapy: Considerations and Guidance from the American Society for Transplantation and Cellular Therapy, European Society for Blood and Marrow Transplantation, and Center for International Blood and Marrow Transplant Research Late Effects and Quality of Life Working Committee

Author

Sharma, Akshay, Badawy, Sherif M., Suelzer, Elizabeth M., Murthy, Hemant S., Prasad, Pinki, Eissa, Hesham, Carpenter, Paul A., Hamadani, Mehdi, Labopin, Myriam, Schoemans, Hélène, Tichelli, André, Phelan, Rachel, Hamilton, Betty K., Buchbinder, David, Im, Annie, Hunter, Rebecca, Brazauskas, Ruta, and Burns, Linda J.

Published
2021
Full Text
View/download PDF

8. Systematic reviews in hematopoietic cell transplantation and cellular therapy: considerations and guidance from the American Society for Transplantation and Cellular Therapy, European Society for Blood and Marrow Transplantation, and the Center for International Blood and Marrow Transplant Research late effects and quality of life working committee

Author

Sharma, Akshay, Badawy, Sherif M., Suelzer, Elizabeth M., Murthy, Hemant S., Prasad, Pinki, Eissa, Hesham, Carpenter, Paul A., Hamadani, Mehdi, Labopin, Myriam, Schoemans, Hélène, Tichelli, André, Phelan, Rachel, Hamilton, Betty K., Buchbinder, David, Im, Annie, Hunter, Rebecca, Brazauskas, Ruta, and Burns, Linda J.

Published
2021
Full Text
View/download PDF

11. Development of a patient-reported outcome questionnaire for aplastic anemia and paroxysmal nocturnal hemoglobinuria (PRO-AA/PNH)

Author

Kimmo Weisshaar, Hannah Ewald, Jörg Halter, Sabine Gerull, Sandra Schönfeld, Yuliya Senft, Maria Martinez, Anne Leuppi-Taegtmeyer, Nina Khanna, Birgit Maier, Antonio Risitano, Regis Peffault de Latour, Andre Tichelli, Jakob Passweg, and Beatrice Drexler

Subjects
Aplastic anemia, Paroxysmal nocturnal hemoglobinuria, Patient-reported outcome, Quality of life, Symptom, Medicine
Abstract

Abstract Background The introduction of new therapy modalities has significantly improved the outcome of aplastic anemia (AA) and paroxysmal nocturnal hemoglobinuria (PNH) patients. However, relatively little is known about the exact disease burden of AA/PNH since standardized assessments of symptoms including health-related quality of life (HRQoL) are frequently missing or inadequately designed for this rare patient group. We aimed to develop AA/PNH-specific questionnaires for self-reporting of symptoms, which could be included in electronic platforms for data collection and patient care. Methods By scoping review, we extracted any reported symptoms in AA/PNH and their prevalence from the literature (Phase I). Consensus rounds with patients and medical experts were conducted to identify core symptoms reported in the literature and to add missing items (Phase II). Ultimately, AA/PNH-specific patient-reported outcome (PRO) questionnaires including the selected measures were designed (Phase III). Results AA symptoms from 62 and PNH symptoms from 45 observational studies were extracted from the literature. Twenty-four patients and seven medical experts identified 11 core symptoms including HRQoL issues after three consensus rounds. Significant differences in the symptom ranking of patients versus medical experts could be observed. Therefore, patient- as well as expert-centered PRO questionnaires in AA and PNH were created following the concepts of validated instruments. Conclusion The development of symptom self-reporting questionnaires for AA and PNH was feasible and the disease-specific PRO questionnaires can now be validated within a web-based workflow in a subsequent feasibility study.

Published
2020
Full Text
View/download PDF

13. Non-Graft-versus-Host Disease Ocular Complications after Hematopoietic Cell Transplantation: Expert Review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and the Transplant Complications Working Party of the European Society for Blood and Marrow Transplantation

Author

Inamoto, Yoshihiro, Petriček, Igor, Burns, Linda, Chhabra, Saurabh, DeFilipp, Zachariah, Hematti, Peiman, Rovó, Alicia, Schears, Raquel, Shah, Ami, Agrawal, Vaibhav, Ahmed, Aisha, Ahmed, Ibrahim, Ali, Asim, Aljurf, Mahmoud, Alkhateeb, Hassan, Beitinjaneh, Amer, Bhatt, Neel, Buchbinder, Dave, Byrne, Michael, Callander, Natalie, Fahnehjelm, Kristina, Farhadfar, Nosha, Gale, Robert Peter, Ganguly, Siddhartha, Hashmi, Shahrukh, Hildebrandt, Gerhard C., Horn, Erich, Jakubowski, Ann, Kamble, Rammurti T., Law, Jason, Lee, Catherine, Nathan, Sunita, Penack, Olaf, Pingali, Ravi, Prasad, Pinki, Pulanic, Drazen, Rotz, Seth, Shreenivas, Aditya, Steinberg, Amir, Tabbara, Khalid, Tichelli, André, Wirk, Baldeep, Yared, Jean, Basak, Grzegorz W., Battiwalla, Minoo, Duarte, Rafael, Savani, Bipin N., Flowers, Mary E.D., Shaw, Bronwen E., and Valdés-Sanz, Nuria

Published
2019
Full Text
View/download PDF

14. Jüngste Entwicklungen in der Hämatologie, Teil 2

Author

Duchosal, Michel A., primary, Alberio, Lorenzo, additional, Angelillo-Scherrer, Anne, additional, Arber, Caroline, additional, Balabanov, Stefan, additional, Blum, Sabine, additional, Bttcher, Steffen, additional, Buser, Andreas, additional, Cairoli, Anne, additional, Chalandon, Yves, additional, Driessen, Christoph, additional, Fontana, Stefano, additional, Grandoni, Francesco, additional, Gregor, Michael, additional, Infanti, Laura, additional, Lambert, Jean-Franois, additional, Meyer, Sara Christina, additional, Passweg, Jakob, additional, Azur Porret, Naomi, additional, Rossi, Davide, additional, Schoumans, Jacqueline, additional, Schwotzer, Rahel, additional, Stssi, Georg, additional, Studte, Jan-Dirk, additional, Theocharides, Alexandre, additional, Tichelli, Andr, additional, Widmer, Corinne, additional, and Zenz, Thorsten, additional

Published
2023
Full Text
View/download PDF

15. Développements récents en hématologie, Partie 2

Author

Duchosal, Michel A., primary, Alberio, Lorenzo, additional, Angelillo-Scherrer, Anne, additional, Arber, Caroline, additional, Balabanov, Stefan, additional, Blum, Sabine, additional, Bttcher, Steffen, additional, Buser, Andreas, additional, Cairoli, Anne, additional, Chalandon, Yves, additional, Driessen, Christoph, additional, Fontana, Stefano, additional, Grandoni, Francesco, additional, Gregor, Michael, additional, Infanti, Laura, additional, Lambert, Jean-Franois, additional, Meyer, Sara Christina, additional, Passweg, Jakob, additional, Azur Porret, Naomi, additional, Rossi, Davide, additional, Schoumans, Jacqueline, additional, Schwotzer, Rahel, additional, Stssi, Georg, additional, Studte, Jan-Dirk, additional, Theocharides, Alexandre, additional, Tichelli, Andr, additional, Widmer, Corinne, additional, and Zenz, Thorsten, additional

Published
2023
Full Text
View/download PDF

16. Développements récents en hématologie, Teil 1

Author

Duchosal, Michel A., primary, Alberio, Lorenzo, additional, Angelillo-Scherrer, Anne, additional, Arber, Caroline, additional, Balabanov, Stefan, additional, Blum, Sabine, additional, Bttcher, Steffen, additional, Buser, Andreas, additional, Cairoli, Anne, additional, Chalandon, Yves, additional, Driessen, Christoph, additional, Fontana, Stefano, additional, Grandoni, Francesco, additional, Gregor, Michael, additional, Infanti, Laura, additional, Lambert, Jean-Franois, additional, Meyer, Sara Christina, additional, Passweg, Jakob, additional, Azur Porret, Naomi, additional, Rossi, Davide, additional, Schoumans, Jacqueline, additional, Schwotzer, Rahel, additional, Studt, Jan-Dirk, additional, Stssi, Georg, additional, Theocharides, Alexandre, additional, Tichelli, Andr, additional, Widmer, Corinne, additional, and Zenz, Thorsten, additional

Published
2023
Full Text
View/download PDF

17. Jüngste Entwicklungen in der Hämatologie, Teil 1

Author

Duchosal, Michel A., primary, Alberio, Lorenzo, additional, Angelillo-Scherrer, Anne, additional, Arber, Caroline, additional, Balabanov, Stefan, additional, Blum, Sabine, additional, Bttcher, Steffen, additional, Buser, Andreas, additional, Cairoli, Anne, additional, Chalandon, Yves, additional, Driessen, Christoph, additional, Fontana, Stefano, additional, Grandoni, Francesco, additional, Gregor, Michael, additional, Infanti, Laura, additional, Lambert, Jean-Franois, additional, Meyer, Sara Christina, additional, Passweg, Jakob, additional, Azur Porret, Naomi, additional, Rossi, Davide, additional, Schoumans, Jacqueline, additional, Schwotzer, Rahel, additional, Studt, Jan-Dirk, additional, Stssi, Georg, additional, Theocharides, Alexandre, additional, Tichelli, Andr, additional, Widmer, Corinne, additional, and Zenz, Thorsten, additional

Published
2023
Full Text
View/download PDF

18. PB2574: HEMOPHAGOCYTIC SYNDROME IN ADULTS - REAL-WORLD DATA ON MORTALITY FROM A TERTIARY REFERENCE CENTER

Author

Wojtovicova, Tatiana, primary, Aujesky, Drahomir, additional, Jakob, Stephan, additional, Bonadies, Nicolas, additional, Furrer, Hansjakob, additional, Novak, Urban, additional, Pabst, Thomas, additional, Maurer, Britta, additional, Möller, Burkhard, additional, Abegglen, Roman Christian, additional, Exadaktylos, Aristomenis, additional, Berzigotti, Annalisa, additional, Banz, Yara, additional, Bacher, Vera Ulrike, additional, Zeerleder, Sacha S., additional, Schefold, Joerg C., additional, Tichelli, André, additional, Angelillo-Scherrer, Anne, additional, and Rovó, Alicia, additional

Published
2023
Full Text
View/download PDF

20. Non-GVHD ocular complications after hematopoietic cell transplantation: expert review from the Late Effects and Quality of Life Working Committee of the CIBMTR and Transplant Complications Working Party of the EBMT

Author

Inamoto, Yoshihiro, Petriček, Igor, Burns, Linda, Chhabra, Saurabh, DeFilipp, Zack, Hematti, Peiman, Rovó, Alicia, Schears, Raquel, Shah, Ami, Agrawal, Vaibhav, Al-Khinji, Aisha, Ahmed, Ibrahim, Ali, Asim, Aljurf, Mahmoud, Alkhateeb, Hassan, Beitinjaneh, Amer, Bhatt, Neel, Buchbinder, Dave, Byrne, Michael, Callander, Natalie, Fahnehjelm, Kristina, Farhadfar, Nosha, Gale, Robert Peter, Ganguly, Siddhartha, Hildebrandt, Gerhard C., Horn, Erich, Jakubowski, Ann, Kamble, Rammurti T., Law, Jason, Lee, Catherine, Nathan, Sunita, Penack, Olaf, Pingali, Ravi, Prasad, Pinki, Pulanic, Drazen, Rotz, Seth, Shreenivas, Aditya, Steinberg, Amir, Tabbara, Khalid, Tichelli, André, Wirk, Baldeep, Yared, Jean, Basak, Grzegorz W., Battiwalla, Minoo, Duarte, Rafael, Savani, Bipin N., Flowers, Mary E. D., Shaw, Bronwen E., and Valdés-Sanz, Nuria

Published
2019
Full Text
View/download PDF

21. European experience and risk factor analysis of donor cell-derived leukaemias/MDS following haematopoietic cell transplantation

Author

Engel, Nicole, Rovo, Alicia, Badoglio, Manuela, Labopin, Myriam, Basak, Grzegorz W., Beguin, Yves, Guyotat, Denis, Ljungman, Per, Nagler, Arnon, Schattenberg, Anton, Schroeder, Thomas, Schroyens, Wilfried, Tischer, Johanna, Socie, Gerard, Kolb, Hans-Jochem, Tichelli, Andre, Salooja, Nina, Duarte, Rafael F., and for the Transplant Complications Working Party of the European Society for Blood and Marrow Transplantation

Published
2019
Full Text
View/download PDF

22. Long-term outcome of a randomized controlled study in patients with newly diagnosed severe aplastic anemia treated with antithymocyte globulin and cyclosporine, with or without granulocyte colony-stimulating factor: a Severe Aplastic Anemia Working Party Trial from the European Group of Blood and Marrow Transplantation

Author

André Tichelli, Régis Peffault de Latour, Jakob Passweg, Cora Knol-Bout, Gérard Socié, Judith Marsh, Hubert Schrezenmeier, Britta Höchsmann, Andrea Bacigalupo, Sujith Samarasinghe, Alicia Rovó, Austin Kulasekararaj, Alexander Röth, Dirk-Jan Eikema, Paul Bosman, Peter Bader, Antonio Risitano, and Carlo Dufour

Subjects
Diseases of the blood and blood-forming organs, RC633-647.5
Abstract

This follow-up study of a randomized, prospective trial included 192 patients with newly diagnosed severe aplastic anemia receiving antithymoglobulin and cyclosporine, with or without granulocyte colony-stimulating factor (G-CSF). We aimed to evaluate the long-term effect of G-CSF on overall survival, event-free survival, probability of secondary myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML), clinical paroxysmal nocturnal hemoglobinuria, relapse, avascular osteonecrosis and chronic kidney disease. The median follow-up was 11.7 years (95% CI, 10.9-12.5). The overall survival rate at 15 years was 57±12% in the group given G-CSF and 63±12% in the group not given G-CSF (P=0.92); the corresponding event-free survival rates were 24±10% and 23±10%, respectively (P=0.36). In total, 9 patients developed MDS or AML, 10 only a clonal cytogenetic abnormality, 7 a solid cancer, 18 clinical paroxysmal nocturnal hemoglobinuria, 8 osteonecrosis, and 12 chronic kidney disease, without any difference between patients treated with or without G-CSF. The cumulative incidence of MDS, AML or isolated cytogenetic abnormality at 15 years was 8.5±3% for the G-CSF group and 8.2±3% for the non-G-CSF group (P=0.90). The cumulative incidence of any late event including myelodysplastic syndrome or acute myeloid leukemia, isolated cytogenetic abnormalities, solid cancer, clinical paroxysmal nocturnal hemoglobinuria, aseptic osteonecrosis, chronic kidney disease and relapse was 50±12% for the G-CSF group and 49±12% for the non-G-CSF group (P=0.65). Our results demonstrate that it is unlikely that G-CSF has an impact on the outcome of severe aplastic anemia; nevertheless, very late events are common and eventually affect the prognosis of these patients, irrespectively of their age at the time of immunosuppressive therapy (NCT01163942).

Published
2020
Full Text
View/download PDF

29. Correction: Systematic reviews in hematopoietic cell transplantation and cellular therapy: considerations and guidance from the American Society for Transplantation and Cellular Therapy, European Society for Blood and Marrow Transplantation, and the Center for International Blood and Marrow Transplant Research late effects and quality of life working committee

Author

Sharma, Akshay, Badawy, Sherif M., Suelzer, Elizabeth M., Murthy, Hemant S., Prasad, Pinki, Eissa, Hesham, Carpenter, Paul A., Hamadani, Mehdi, Labopin, Myriam, Schoemans, Hélène, Tichelli, André, Phelan, Rachel, Hamilton, Betty K., Buchbinder, David, Im, Annie, Hunter, Rebecca, Brazauskas, Ruta, and Burns, Linda J.

Published
2021
Full Text
View/download PDF

32. Translational longevity medicine: a Swiss perspective in an ageing country

Author

Ruckstuhl, Marco M., Bischof, Evelyne, Blatch, Dana, Buhayer, Aliki, Goldhahn, Jörg, Battegay, Edouard, Tichelli, Andre, and Ewald, Collin Y.

Subjects
aged, longevity, delivery of health care, aging, chronic disease, humans, Switzerland, ddc:610, Medical sciences, medicine
Abstract

Breakthroughs in medical research in the last century have led to a significant extension of the human lifespan, resulting in a shift towards an elderly population worldwide. Due to the ongoing progress of global development towards elevated standards of living, this study specifically examines Switzerland as a representative nation to explore the socioeconomic and healthcare ramifications associated with an ageing population, thereby highlighting the tangible impact experienced in this context. Beyond the exhaustion of pension funds and medical budgets, by reviewing the literature and analysing publicly available data, we observe a "Swiss Japanification". Old age is associated with late-life comorbidities and an increasing proportion of time spent in poor health. To address these problems, a paradigm shift in medical practice is needed to improve health rather than respond to existing diseases. Basic ageing research is gaining momentum to be translated into therapeutic interventions and provides machine learning tools driving longevity medicine. We propose that research focus on closing the translational gap between the molecular mechanisms of ageing and a more prevention-based medicine, which would help people age better and prevent late-life chronic diseases., Swiss Medical Weekly, 153 (6), ISSN:1424-7860, ISSN:1424-3997

Published
2023
Full Text
View/download PDF

34. The future of accreditation of continuing medical education (CME)-continuing professional development (CPD) in Europe: harmonisation through dialogue and consensus

Author

Fabiola de Andrade, Reinhard Griebenow, Richard W. Costello, Margarita Guenova, Robert Schaefer, James D. Chalmers, Andre Tichelli, Drazen Raguz, and Joerg Stein

Subjects
Continuing medical education (CME), continuing professional development (CPD), accreditation, Europe, continuing medical education-European accreditors (CME-EA), Special aspects of education, LC8-6691, Medicine (General), R5-920
Abstract

In Europe, there are currently some 30 different jurisdictions and no overarching legislation regarding CME-CPD accreditation, since legislative competency related to national health-care systems lies with national authorities. Thus, public demonstration of professional agreement regarding the principles, rules and practice of CME-CPD as well as its accreditation is a highly desirable professional and political objective in Europe, where free movement and freedom to offer professional (medical) services is a key feature of the EU vision of the single market. The newly formed association of independent European accreditors, Continuing Medical Education - European Accreditors (CME-EA) is committed to offering a platform for dialogue between individuals and organisations involved in definition of professional codes in general, and accreditation of CME-CPD in particular on the national level. The aim is to reach a European consensus on principles and rules applied in planning and delivery of CME-CPD. This includes consensus on constituent characteristics of accreditors as well as principles and practice of accreditation.

Published
2018
Full Text
View/download PDF

35. Male-specific late effects in adult hematopoietic cell transplantation recipients: a systematic review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and Transplant Complications Working Party of the European Society of Blood and Marrow Transplantation

Author

Shahrukh K. Hashmi, Jean A. Yared, Arthur Flatau, Sunita Nathan, Yoshihiro Inamoto, Dipnarine Maharaj, Bipin N. Savani, Lana Desnica Grkovic, André Tichelli, Mahmoud Aljurf, Stephanie M. Smith, Rachel Phelan, Hélène Schoemans, Richard J. Ross, Lauren M. Walker, Robert Peter Gale, Zachariah DeFilipp, Daniel Wolff, Karen C. Baker, Hesham Eissa, Sherif M. Badawy, Hermann Einsele, Alicia Rovó, Isabel Sanchez-Ortega, Maria Teresa Lupo-Stanghellini, Douglas Tremblay, Michael L. Eisenberg, Hildegard T. Greinix, Hemant S. Murthy, Annie Im, Amir Steinberg, Grzegorz W. Basak, Peiman Hematti, Tal Schechter, Andrea Salonia, David Buchbinder, Elizabeth M. Suelzer, Vaibhav Agrawal, Steven Pavletic, Kareem Jamani, John Murray, Seema Naik, Ami J. Shah, Sarah C. Vij, Akshay Sharma, Rebecca Hunter, Zinaida Peric, Narendranath Epperla, Linda J. Burns, Ajoy Dias, Nosha Farhadfar, Pinki Prasad, John A. Snowden, Betty K. Hamilton, D. Pulanić, Phelan, Rachel, Im, Annie, Hunter, Rebecca L, Inamoto, Yoshihiro, Lupo-Stanghellini, Maria Teresa, Rovo, Alicia, Badawy, Sherif M, Burns, Linda, Eissa, Hesham, Murthy, Hemant S, Prasad, Pinki, Sharma, Akshay, Suelzer, Elizabeth, Agrawal, Vaibhav, Aljurf, Mahmoud, Baker, Karen, Basak, Grzegorz W, Buchbinder, David, Defilipp, Zachariah, Grkovic, Lana Desnica, Dias, Ajoy, Einsele, Hermann, Eisenberg, Michael L, Epperla, Narendranath, Farhadfar, Nosha, Flatau, Arthur, Gale, Robert Peter, Greinix, Hildegard, Hamilton, Betty K, Hashmi, Shahrukh, Hematti, Peiman, Jamani, Kareem, Maharaj, Dipnarine, Murray, John, Naik, Seema, Nathan, Sunita, Pavletic, Steven, Peric, Zinaida, Pulanic, Drazen, Ross, Richard, Salonia, Andrea, Sanchez-Ortega, Isabel, Savani, Bipin N, Schechter, Tal, Shah, Ami J, Smith, Stephanie M, Snowden, John A, Steinberg, Amir, Tremblay, Dougla, Vij, Sarah C, Walker, Lauren, Wolff, Daniel, Yared, Jean A, Schoemans, Hélène, and Tichelli, André

Subjects
Adult, Male, Infertility, medicine.medical_specialty, Evidence-based practice, Sexual Dysfunction, Survivorship, Late effects, Male-specific, Hematopoietic cell transplantation, Genital, Chronic graft-versus-host disease, Hypogonadism, Sexual dysfunction, Subsequent malignancies, Population, Graft vs Host Disease, 610 Medicine & health, Disease, Article, Testicular Neoplasms, Quality of life, Bone Marrow, medicine, Humans, Immunology and Allergy, Hematopoietic Cell Transplantation, Intensive care medicine, education, Late Effects, Reproductive health, education.field_of_study, Subsequent Malignancies, Transplantation, business.industry, Male-Specific, Hematopoietic Stem Cell Transplantation, Cell Biology, Hematology, medicine.disease, Transplant Recipients, surgical procedures, operative, Genital Chronic Graft-versus-Host Disease, Disease Progression, Quality of Life, Molecular Medicine, Female, medicine.symptom, business
Abstract

Background : Male-specific late effects after hematopoietic cell transplantation (HCT) include genital chronic graft-versus-host disease (GvHD), hypogonadism, sexual dysfunction, infertility, and subsequent malignancies, such as prostate, penile, and testicular cancer. They may be closely intertwined and cause prolonged morbidity and decreased quality of life after HCT. Objective : Here, we provide a systematic review of male-specific late effects in a collaboration between transplant physicians, endocrinologists, urologists, dermatologists, and sexual health professionals through the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research, and the Transplant Complications Working Party of the European Society of Blood and Marrow Transplantation. Study Design : We utilized systematic review methodology to summarize incidence, risk factors, screening, prevention and treatment of these complications and provide consensus evidence-based recommendations for clinical practice and future research. Results : Most of the evidence regarding male GvHD is still based on limited data, precluding strong therapeutic recommendations. We therefore recommend to systematically screen for male genital GvHD regularly and report it to large registries to allow for a better understanding. Future research should also address treatment since little published evidence is available to date. Male-specific endocrine consequences of HCT include hypogonadism which may also affect bone health. Since the evidence is scarce, current recommendations for hormone substitution and/or bone health treatment are based on similar principles as for the general population. Following HCT, sexual health decreases and this topic should be addressed at regular intervals. Future studies should focus on interventional strategies to address sexual dysfunction. Infertility remains prevalent in patients having undergone myeloablative conditioning, which warrants offering sperm preservation in all HCT candidates. Most studies on fertility rely on descriptive registry analysis and surveys, hence the importance of reporting post-HCT conception data to large registries. Although the quality of evidence is low, the development of cancer in male genital organs does not seem more prevalent than in the general population; however, subsequent malignancies in general seem to be more prevalent in males than females, and special attention should be given to skin and oral mucosa. Conclusion : Male-specific late effects, probably more under-reported than female-specific complications, should be systematically considered during the regular follow-up visits of male survivors who have undergone HCT. Care of patients with male-specific late effects warrants close collaboration between transplant physicians and specialists from other involved disciplines. Future research should be directed towards better data collection on male-specific late effects and on studies about the interrelationship between these late effects, to allow the development of evidence based effective management practices.

Published
2022

36. Correction: Non-GVHD ocular complications after hematopoietic cell transplantation: expert review from the Late Effects and Quality of Life Working Committee of the CIBMTR and Transplant Complications Working Party of the EBMT

Author

Inamoto, Yoshihiro, Petriček, Igor, Burns, Linda, Chhabra, Saurabh, DeFilipp, Zack, Hematti, Peiman, Rovó, Alicia, Schears, Raquel, Shah, Ami, Agrawal, Vaibhav, Al-Khinji, Aisha, Ahmed, Ibrahim, Ali, Asim, Aljurf, Mahmoud, Alkhateeb, Hassan, Beitinjaneh, Amer, Bhatt, Neel, Buchbinder, Dave, Byrne, Michael, Callander, Natalie, Fahnehjelm, Kristina, Farhadfar, Nosha, Gale, Robert Peter, Ganguly, Siddhartha, Hildebrandt, Gerhard C., Horn, Erich, Jakubowski, Ann, Kamble, Rammurti T., Law, Jason, Lee, Catherine, Nathan, Sunita, Penack, Olaf, Pingali, Ravi, Prasad, Pinki, Pulanic, Drazen, Rotz, Seth, Shreenivas, Aditya, Steinberg, Amir, Tabbara, Khalid, Tichelli, André, Wirk, Baldeep, Yared, Jean, Basak, Grzegorz W., Battiwalla, Minoo, Duarte, Rafael, Savani, Bipin N., Flowers, Mary E. D., Shaw, Bronwen E., and Valdés-Sanz, Nuria

Published
2019
Full Text
View/download PDF

37. List of Contributors

Author

Ahmed, S.O., primary, Aldawsari, G., additional, Aljurf, M.D., additional, Alzahrani, H., additional, Ayas, M., additional, Bacigalupo, A., additional, Ciceri, F., additional, Cooper, J.N., additional, Dalle, J.H., additional, Dufour, C., additional, Elmahdi, S., additional, Farruggia, P., additional, Fioredda, F., additional, Gandhi, S., additional, Giraudier, S., additional, Gluckman, E., additional, Grimaldi, F., additional, Höchsmann, B., additional, Hosokawa, K., additional, Kojima, S., additional, Leblanc, T., additional, Marsh, J.C.W., additional, Meyran, D., additional, Miano, M., additional, Mufti, G.J., additional, Passweg, J.R., additional, de Latour, R. Peffault, additional, Risitano, A.M., additional, Rovó, A., additional, Ruggeri, A., additional, Samarasinghe, S., additional, Scheinberg, P., additional, Schrezenmeier, H., additional, Sica, S., additional, Stanghellini, M.T.L., additional, Tichelli, A., additional, Van Lint, M.T., additional, Warren, A.J., additional, and Young, N.S., additional

Published
2017
Full Text
View/download PDF

41. Position paper on current aspects of sponsoring in accredited CME

Author

Daiana Stolz, Reinhard Griebenow, Andre Tichelli, Andrew J. Ullmann, Richard W. Costello, Lampros Michalis, Margarita Guenova, Sandy Sutter, Fabiola De Andrade, and Robert Schaefer

Subjects
European Specialty Accreditation Boards, independent CME, sponsoring, transparency, professional congress organiser (PCO), medical education company, information material, Special aspects of education, LC8-6691, Medicine (General), R5-920
Abstract

This position paper is the result of a collaborative approach of several European Specialty Accreditation Boards (ESABs) and, has been stimulated by their current experience in accreditation regarding roles and responsibilities assumed by sponsors of accredited continuing medical education (CME). The suggestions made in this paper aim to preserve the fundamental principle in CME accreditation that the physician in charge of the programme has sole responsibility for the selection of topics, speakers, content and format, as well as mode of presentation, and that sponsors will under no circumstances interfere with this principle. This is considered as a responsibility of an individual physician (or physicians), which cannot be delegated, even in part, to third parties. This responsibility has been extended to include all communication before and after the event. The paper also identifies undecided issues, about which ESABs are committed to elaborate proposals in the future.

Published
2017
Full Text
View/download PDF

43. Long‐term follow‐up program and transplant clinic setup

Author

Navneet S. Majhail, André Tichelli, Bipin N. Savani, Alicia Rovó, and Shahrukh K. Hashmi

Subjects
Pediatrics, medicine.medical_specialty, Long term follow up, business.industry, medicine, Transplant clinic, business
Published
2021

46. Long‐term follow‐up calendar

Author

André Tichelli, Shahrukh Hashmi, Alicia Rovó, Navneet S. Majhail, and Bipin N. Savani

Subjects
Pediatrics, medicine.medical_specialty, Long term follow up, business.industry, Medicine, business
Published
2021

47. Ocular complications

Author

Alicia Rovó, André Tichelli, and Yoshihiro Inamoto

Published
2021

48. JAK2 Unmutated Polycythaemia—Real-World Data of 10 Years from a Tertiary Reference Hospital

Author

Jalowiec, Katarzyna Aleksandra, primary, Vrotniakaite-Bajerciene, Kristina, additional, Jalowiec, Jakub, additional, Frey, Noel, additional, Capraru, Annina, additional, Wojtovicova, Tatiana, additional, Joncourt, Raphael, additional, Angelillo-Scherrer, Anne, additional, Tichelli, Andre, additional, Porret, Naomi Azur, additional, and Rovó, Alicia, additional

Published
2022
Full Text
View/download PDF

49. Male-Specific Late Effects in Adult Hematopoietic Cell Transplantation Recipients: A Systematic Review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and Transplant Complications Working Party of the European Society of Blood and Marrow Transplantation

Author

Phelan, Rachel, primary, Im, Annie, additional, Hunter, Rebecca L., additional, Inamoto, Yoshihiro, additional, Lupo-Stanghellini, Maria Teresa, additional, Rovo, Alicia, additional, Badawy, Sherif M., additional, Burns, Linda, additional, Eissa, Hesham, additional, Murthy, Hemant S., additional, Prasad, Pinki, additional, Sharma, Akshay, additional, Suelzer, Elizabeth, additional, Agrawal, Vaibhav, additional, Aljurf, Mahmoud, additional, Baker, Karen, additional, Basak, Grzegorz W., additional, Buchbinder, David, additional, DeFilipp, Zachariah, additional, Grkovic, Lana Desnica, additional, Dias, Ajoy, additional, Einsele, Hermann, additional, Eisenberg, Michael L., additional, Epperla, Narendranath, additional, Farhadfar, Nosha, additional, Flatau, Arthur, additional, Gale, Robert Peter, additional, Greinix, Hildegard, additional, Hamilton, Betty K., additional, Hashmi, Shahrukh, additional, Hematti, Peiman, additional, Jamani, Kareem, additional, Maharaj, Dipnarine, additional, Murray, John, additional, Naik, Seema, additional, Nathan, Sunita, additional, Pavletic, Steven, additional, Peric, Zinaida, additional, Pulanic, Drazen, additional, Ross, Richard, additional, Salonia, Andrea, additional, Sanchez-Ortega, Isabel, additional, Savani, Bipin N., additional, Schechter, Tal, additional, Shah, Ami J., additional, Smith, Stephanie M., additional, Snowden, John A., additional, Steinberg, Amir, additional, Tremblay, Douglas, additional, Vij, Sarah C., additional, Walker, Lauren, additional, Wolff, Daniel, additional, Yared, Jean A., additional, Schoemans, Hélène, additional, and Tichelli, André, additional

Published
2022
Full Text
View/download PDF

50. STAT3 mutations indicate the presence of subclinical T-cell clones in a subset of aplastic anemia and myelodysplastic syndrome patients

Author

Jerez, Andres, Clemente, Michael J., Makishima, Hideki, Rajala, Hanna, Gómez-Seguí, Ines, Olson, Thomas, McGraw, Kathy, Przychodzen, Bartlomiej, Kulasekararaj, Austin, Afable, Manuel, Husseinzadeh, Holleh D., Hosono, Naoko, LeBlanc, Francis, Lagström, Sonja, Zhang, Dan, Ellonen, Pekka, Tichelli, André, Nissen, Catherine, Lichtin, Alan E., Wodnar-Filipowicz, Aleksandra, Mufti, Ghulam J., List, Alan F., Mustjoki, Satu, Loughran, Thomas P., Jr, and Maciejewski, Jaroslaw P.

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results