Search

Purpose: The aim is to provide new insights for researchers studying the pathogenesis of diabetic cognitive dysfunction and promoting the wider use of natural products in their treatment. Method: First, the Web of Science Core Collection was selected as the data source for a computerized literature search on oxidative stress and diabetic cognitive dysfunction (DCD). Next, Biblimetrix and VOSviewer performed statistical analysis focusing on publication countries, institutions, authors, research hotspots, and emerging directions in the field. Then, through the analysis of keywords and key articles, the forefront of the field is identified. Finally, we discussed the pathogenesis of DCD, the influence of oxidative stress on DCD and the antioxidant effect of natural products on DCD. Result: 293 valid papers were obtained. Bibliometrics showed that oxidative stress, diabetes, Alzheimer's disease (AD), cognitive decline, insulin resistance and quercetin were the key words of the symbiotic network. Conclusion: The antioxidant effects of natural products in improving DCD have been extensively studied in preclinical studies, providing potential for their treatment in DCD, but their evaluation in clinical trials is currently uncommon. [ABSTRACT FROM AUTHOR]

Tetramethylammonium glycine ([N1111][Gly]) can be completely ionized into cation [N1111]+ and anion [Gly]- in aqueous solution. The anion contains an amino -NH2 and a carboxyl -COO-, both of which can react with hydrogen sulfide (H2S). Therefore, [N1111][Gly] was used to promote the selective absorption of H2S in coke oven gas (COG) by N-methyldiethanolamine (MDEA). The absorption performance and selectivity of H2S in the aqueous solution of MDEA-[N1111][Gly] were investigated. The effects of MDEA mass fraction, [N1111][Gly] mass fraction, temperature, H2S partial pressure and CO2 partial pressure on the absorption capacity and selectivity were clarified. The results showed that an aqueous solution of MDEA-[N1111][Gly] has good selectivity for H2S in COG. The absorption capacity was large and the mass fraction of the solute in the absorbent reached more than 0.55, thereby having outstanding advantages in the aspects of saving energy consumption and operating cost and having a good application potential. [ABSTRACT FROM AUTHOR]

Purpose: The aim is to provide new insights for researchers studying the pathogenesis of diabetic cognitive dysfunction and promoting the wider use of natural products in their treatment., Method: First, the Web of Science Core Collection was selected as the data source for a computerized literature search on oxidative stress and diabetic cognitive dysfunction (DCD). Next, Biblimetrix and VOSviewer performed statistical analysis focusing on publication countries, institutions, authors, research hotspots, and emerging directions in the field. Then, through the analysis of keywords and key articles, the forefront of the field is identified. Finally, we discussed the pathogenesis of DCD, the influence of oxidative stress on DCD and the antioxidant effect of natural products on DCD., Result: 293 valid papers were obtained. Bibliometrics showed that oxidative stress, diabetes, Alzheimer's disease (AD), cognitive decline, insulin resistance and quercetin were the key words of the symbiotic network., Conclusion: The antioxidant effects of natural products in improving DCD have been extensively studied in preclinical studies, providing potential for their treatment in DCD, but their evaluation in clinical trials is currently uncommon., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Tu, Xu, Li, Tian, Cao, Wang and Qu.)