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The proton density distribution of 206Hg is calculated in the framework of the Skyrme-Hartree-Fock approach with the SLy5, SLy5+T, and SLy5+Tw interactions. It is shown that the central density drops strongly with the SLy5 and SLy5+T interactions due to the vacancy of the 3s1/2 orbital. This means that the density depression in the interior of the nucleus is not so much influenced by the tensor force of the SLy5+T interaction. However, with the SLy5+Tw interaction the bubble structure does not exist because the tensor force effect of this interaction leads to the inversion between the single-proton states 3s1/2 and 1h11/2 (3s1/2-1h11/2 inversion) so that the 3s1/2 state is fully occupied by protons. In addition, a detailed discussion on the antibubble effect from the pairing interaction is performed by using the Skyrme-Hartree-Fock-Bogoliubov approach. It is found that a proton bubble structure in Hg206 is unlikely to appear because of the paring correlation. [ABSTRACT FROM AUTHOR]

Objective: To investigate the relationship between occupational chronic psychological stress with heat shock protein 70 (HSP70) and tumor necrosis factor-alpha (TNF-α)., Methods: Using case-control study design, we selected 622 cases in 20 to 60 years old and unrelated patients with metabolic syndrome as the case group between October 2011 and October 2012 at two hospitals of Ningxia hui autonomous region. At the same time, we selected 600 healthy people from health check-up crowd in the above two hospitals as control group. The the research objects were sex, age, nation, height, weight, smoking, drinking, exercise, and so on. After informed consent, all the research objects were collected fasting venous blood samples 10 ml in order to proceed laboratory testing of biochemical indicators. The expression of HSP70 and TNF-α in serum was determined by ELISA. Using the revised occupational stress inventory (OSI) to survey the occupational chronic psychological stress factors and stress level of research object. The correlation of occupational chronic psychological stress scores with HSP70 and TNF-α was investigated by partial correlation analysis. We built a multivariate linear regression equation With HSP70 and TNF alpha as the independent variable and occupational chronic psychological stress scores as the dependent variable, using equation of the determination coefficient R(2) to judge the degree of fitting equation., Results: The total points of chronic stress factors in all respondents was (136.65±16.19). Among them, the mild stress level group was 313, moderate was 588, severe was 321, chronic heart stress factors scores were (119.96±13.30), (135.33±3.23), (155.33±13.55) points, respectively. In the case group subjects, the expression of HSP70 in mild, moderate and severe occupational chronic psychological stress levels were (29.88±30.08), (36.38±30.08), (27.16±23.77) ng/ml (F=6.85, P=0.001). The control group were (27.64±9.89), (39.78±29.77), (3.94±3.09) ng/ml (F=125.71, P<0.001). Multiple linear regression analysis showed the expression of psychological stress and HSP70 was a negative linear relationship, while positive linear relationship with TNF-α, the fitting of the regression equation was y=-0.07x1+ 0.011x2+ 136.88. Partial correlation analysis results showed that the occupational chronic psychological stress scores and negatively correlated with HSP70 (r=-0.11, P<0.001) and was positively related with TNF-α (r=0.11, P<0.001). In all survey respondents, the expression of HSP70 in mild, moderate and severe occupational chronic psychological stress levels group were (28.49±20.10), (37.99±29.96), (17.98±21.77) ng/ml (F=64.08, P<0.001). The expression of TNF-α were (133.61±129.51), (171.23±133.69), (169.31±196.09) pg/ml (F=6.93, P=0.001)., Conclusion: The expression levels of HSP70 and TNF-α in serum were affected by occupational chronic psychological stress. While the level of occupational chronic psychological stress increased, the expression level of HSP70 in serum reduced, the expression level of TNF-α raised.