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105 results on '"Thymine DNA Glycosylase genetics"'

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1. Enhanced thermal stability enables human mismatch-specific thymine-DNA glycosylase to catalyse futile DNA repair.

2. DCAF2 regulates the proliferation and differentiation of mouse progenitor spermatogonia by targeting p21 and thymine DNA glycosylase.

3. Glycosylase-based base editors for efficient T-to-G and C-to-G editing in mammalian cells.

4. Thymine DNA glycosylase regulates cell-cycle-driven p53 transcriptional control in pluripotent cells.

5. Thymine DNA glycosylase mediates chromatin phase separation in a DNA methylation-dependent manner.

6. Comprehensive analysis of the prognostic value and biological function of TDG in hepatocellular carcinoma.

7. Thymine DNA glycosylase is an RNA-binding protein with high selectivity for G-rich sequences.

8. Characterization of a Novel Thermostable DNA Lyase Used To Prepare DNA for Next-Generation Sequencing.

9. Screening of glycosylase activity on oxidative derivatives of methylcytosine: Pedobacter heparinus SMUG2 as a formylcytosine- and carboxylcytosine-DNA glycosylase.

10. Chemical and enzymatic modifications of 5-methylcytosine at the intersection of DNA damage, repair, and epigenetic reprogramming.

11. Tris(1,3-dichloro-2-propyl) phosphate disrupts the trajectory of cytosine methylation within developing zebrafish embryos.

12. Kinetics and thermodynamics of BI-BII interconversion altered by T:G mismatches in DNA.

13. TDG suppresses the migration and invasion of human colon cancer cells via the DNMT3A/TIMP2 axis.

14. Measurement of deaminated cytosine adducts in DNA using a novel hybrid thymine DNA glycosylase.

15. TDG is a pig-specific epigenetic regulator with insensitivity to H3K9 and H3K27 demethylation in nuclear transfer embryos.

16. Roles of TET and TDG in DNA demethylation in proliferating and non-proliferating immune cells.

17. TET-TDG Active DNA Demethylation at CpG and Non-CpG Sites.

18. Correlation between genetic variation in thymine DNA glycosylase and smoking behavior.

19. The Effect of Allopregnanolone on Enzymatic Activity of the DNA Base Excision Repair Pathway in the Sheep Hippocampus and Amygdala under Natural and Stressful Conditions.

20. Thymine DNA glycosylase-regulated TAZ promotes radioresistance by targeting nonhomologous end joining and tumor progression in esophageal cancer.

21. Inducible TDG knockout models to study epigenetic regulation.

22. Inducible TDG knockout models to study epigenetic regulation.

23. Thymine DNA glycosylase is a key regulator of CaMKIIγ expression and vascular smooth muscle phenotype.

24. lncRNA H19 contributes to oxidative damage repair in the early age-related cataract by regulating miR-29a/TDG axis.

25. Thymine DNA glycosylase as a novel target for melanoma.

26. Effect of the thymine-DNA glycosylase rs4135050 variant on Saudi smoker population.

27. Mutations in the DNMT3A DNA methyltransferase in acute myeloid leukemia patients cause both loss and gain of function and differential regulation by protein partners.

28. [Role of MBD4 in hypermutator phenotype and malignant transformation].

29. Defining the impact of sumoylation on substrate binding and catalysis by thymine DNA glycosylase.

30. Genome-wide analysis reveals a role for TDG in estrogen receptor-mediated enhancer RNA transcription and 3-dimensional reorganization.

31. Dynamics of the excised base release in thymine DNA glycosylase during DNA repair process.

32. TET2- and TDG-mediated changes are required for the acquisition of distinct histone modifications in divergent terminal differentiation of myeloid cells.

33. Combinatorial DNA methylation codes at repetitive elements.

34. Regulation of DNA demethylation by the XPC DNA repair complex in somatic and pluripotent stem cells.

35. A G-quadruplex-selective luminescent probe with an anchor tail for the switch-on detection of thymine DNA glycosylase activity.

36. Interaction with the DNA Repair Protein Thymine DNA Glycosylase Regulates Histone Acetylation by p300.

37. miR-29b Targets LPL and TDG Genes and Regulates Apoptosis and Triglyceride Production in MECs.

38. 5-Formylcytosine Could Be a Semipermanent Base in Specific Genome Sites.

39. AP endonuclease 1 prevents the extension of a T/G mismatch by DNA polymerase β to prevent mutations in CpGs during base excision repair.

40. TET2-mediated 5-hydroxymethylcytosine induces genetic instability and mutagenesis.

41. Characterizing Requirements for Small Ubiquitin-like Modifier (SUMO) Modification and Binding on Base Excision Repair Activity of Thymine-DNA Glycosylase in Vivo.

42. Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism.

43. Thymine DNA Glycosylase Gene Knockdown Can Affect the Differentiation of Pig Preadipocytes.

44. Oncogenic Ras suppresses ING4-TDG-Fas axis to promote apoptosis resistance.

45. Dynamic changes of DNA epigenetic marks in mouse oocytes during natural and accelerated aging.

46. MicroRNAs mediated targeting on the Yin-yang dynamics of DNA methylation in disease and development.

47. Mechanism of the Glycosidic Bond Cleavage of Mismatched Thymine in Human Thymine DNA Glycosylase Revealed by Classical Molecular Dynamics and Quantum Mechanical/Molecular Mechanical Calculations.

48. Role of base excision repair in maintaining the genetic and epigenetic integrity of CpG sites.

49. Epigenetic modifications in DNA could mimic oxidative DNA damage: A double-edged sword.

50. DNA methylation patterns of candidate genes regulated by thymine DNA glycosylase in patients with TP53 germline mutations.

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