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Your search keyword '"Thu, Yee-Mon"' showing total 28 results
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28 results on '"Thu, Yee-Mon"'

1. Improved detection of DNA replication fork-associated proteins

Author

Rivard, Rebecca S., Chang, Ya-Chu, Ragland, Ryan L., Thu, Yee-Mon, Kassab, Muzaffer, Mandal, Rahul Shubhra, Van Riper, Susan K., Kulej, Katarzyna, Higgins, LeeAnn, Markowski, Todd M., Shang, David, Hedberg, Jack, Erber, Luke, Garcia, Benjamin, Chen, Yue, Bielinsky, Anja-Katrin, and Brown, Eric J.

Published
2024
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2. GenExSt: A Tool to Identify Correlation of Gene Expression After Normalization with Housekeeping Genes

Author

Bonham-Carter, Oliver, Thu, Yee Mon, Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, and Arai, Kohei, editor

Published
2021
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20. Targeting aurora kinases limits tumour growth through DNA damage‐mediated senescence and blockade of NF‐κB impairs this drug‐induced senescence

Author

Liu, Yan, primary, Hawkins, Oriana E., additional, Su, Yingjun, additional, Vilgelm, Anna E., additional, Sobolik, Tammy, additional, Thu, Yee‐Mon, additional, Kantrow, Sara, additional, Splittgerber, Ryan C., additional, Short, Sarah, additional, Amiri, Katayoun I., additional, Ecsedy, Jeffery A., additional, Sosman, Jeffery A., additional, Kelley, Mark C., additional, and Richmond, Ann, additional

Published
2012
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26. Characterization of Titanium Silicide (TiSi2) for Complementary Metal Oxide Semiconductor.

Author

Thu, Yee Mon and Latt, Khin Maung

Subjects
*TITANIUM silicides, *COMPLEMENTARY metal oxide semiconductors, *SILICIDES, *ELECTRIC resistance, *THERMAL stability, *POLYMORPHIC transformations, *METALLIC films
Abstract

TiSi2 has been one of the most crucial silicides for complementary metal oxide semiconductor device applications such as contacts to source/drain actives and gate regions due to its low resistivity and good thermal stability. However, the polymorphic transformation, (C49-TiSi2 ∼60-70 μω cm→C54-TiSi2 ∼5-20 μωcm), required for self-aligned silicide process has become difficult on narrow, ∼0.25 mm and thin lines, known as fine-line width effect. In the present paper, Titanium thin films of thickness 100 nm are deposited on 6″ (100) single crystal Si wafers by ionized metal plasma deposition method. Then samples are annealed at different temperatures under high vacuum condition to study the for C49-TiSi2 formation of TiSi. Transformation temperatures of C49 to C54 were studied using scanning electron microscopy (SEM), X-ray diffraction (XRD) and four point probe electrical method. [ABSTRACT FROM AUTHOR]

Published
2010
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27. SGS1-SuOff rescues the mild methylmethane sulfonate sensitivity of srs2 Δ cells in Saccharomyces cerevisiae .

Author

Herce-Hagiwara B and Thu YM

Abstract

Sgs1p in Saccharomyces cerevisiae belongs to the RecQ helicase family. Sgs1p is involved in recombination during DNA damage repair and sumoylation of Sgs1p is one mechanism by which the protein is regulated. To further understand the significance of Sgs1p sumoylation in DNA damage repair, we examined the genetic interaction between SGS1 SUMO mutants and a mutant of SRS2 , the protein product of which also prevents aberrant recombination structures. We observed that SGS1-SuOff , a mutant in which Sgs1p cannot be sumoylated, attenuates the mild sensitivity of srs2 Δcells to methyl methane sulfonate., (Copyright: © 2021 by the authors.)

Published
2021
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28. The lymphotoxin-beta receptor is an upstream activator of NF-kappaB-mediated transcription in melanoma cells.

Author

Dhawan P, Su Y, Thu YM, Yu Y, Baugher P, Ellis DL, Sobolik-Delmaire T, Kelley M, Cheung TC, Ware CF, and Richmond A

Subjects
Apoptosis, Cell Line, Tumor, Cell Proliferation, Humans, I-kappa B Kinase metabolism, Melanoma pathology, Neoplasm Invasiveness, Protein Serine-Threonine Kinases metabolism, NF-kappaB-Inducing Kinase, Gene Expression Regulation, Neoplastic, Lymphotoxin beta Receptor metabolism, Melanoma metabolism, NF-kappa B metabolism, Neoplasm Proteins metabolism, Transcription, Genetic
Abstract

The pleiotropic transcription factor nuclear factor-kappaB (NF-kappaB (p50/p65)) regulates the transcription of genes involved in the modulation of cell proliferation, apoptosis, and oncogenesis. Furthermore, a host of solid and hematopoietic tumor types exhibit constitutive activation of NF-kappaB (Basseres, D. S., and Baldwin, A. S. (2006) 25, 6817-6830). However, the mechanism for this constitutive activation of NF-kappaB has not been elucidated in the tumors. We have previously shown that NF-kappaB-inducing kinase (NIK) protein and its association with Inhibitor of kappaB kinase alphabeta are elevated in melanoma cells compared with their normal counterpart, leading to constitutive activation of NF-kappaB. Moreover, expression of dominant negative NIK blocked this base-line NF-kappaB activity in melanoma cells. Of the three receptors that require NIK for activation of NF-kappaB, only the lymphotoxin-beta receptor (LTbeta-R) is expressed in melanoma. We show in this manuscript that for melanoma there is a strong relationship between expression of the LTbeta-R and constitutive NF-kappaB transcriptional activity. Moreover, we show that activation of the LTbeta-R can drive NF-kappaB activity to regulate gene expression that leads to enhanced cell growth. The inhibition by LTbeta-R shRNA resulted in decreased NF-kappaB promoter activity, decreased growth, and decreased invasiveness as compared with control. These results indicate that the LTbeta-R constitutively induces NF-kappaB activation, and this event may be associated with autonomous growth of melanoma cells.

Published
2008
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