1,331 results on '"Thomson, B"'
Search Results
2. Impact of neoadjuvant FOLFIRINOX over upfront resection in borderline resectable pancreatic cancer—an international, multicentre, real-world analysis
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Banks, S., Hong, W., Degeling, K., Shapiro, J., Thomson, B., Ko, H.S., Ananda, S., Jalali, A., To, Y.H., Loveday, B., McLachlan, S.-A., Knowles, B., Fox, A., Michael, M., Wong, R., Burge, M., Clarke, K., Pattison, S., Nikfarjam, M., Zielinski, R., Day, F., Chee, C.E., Nagrial, A., IJzerman, M., Gibbs, P., and Lee, B.
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- 2024
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3. When a LIC came to town: The impact of longitudinal integrated clerkships on a rural community of healthcare practice
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Hudson, J N, Thomson, B, Weston, K M, and Knight-Billington, P J
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- 2015
4. Evolving patterns of metastatic spread, treatment, and outcome for patients with oligometastatic colorectal cancer
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Pham, H, Ramanujam, S, Yeoh, H-L, Antippa, P, Houli, N, Thomson, B, Kosmider, S, Dunn, C, To, YH, Lee, M, Wong, V, Caird, S, Shapiro, J, Burge, M, Wong, H-L, Ma, B, Lim, SH-S, Torres, J, Lee, B, Smith, M, Gibbs, P, Pham, H, Ramanujam, S, Yeoh, H-L, Antippa, P, Houli, N, Thomson, B, Kosmider, S, Dunn, C, To, YH, Lee, M, Wong, V, Caird, S, Shapiro, J, Burge, M, Wong, H-L, Ma, B, Lim, SH-S, Torres, J, Lee, B, Smith, M, and Gibbs, P
- Published
- 2024
5. Artificial Intelligence to Facilitate Clinical Trial Recruitment in Age-Related Macular Degeneration
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Williamson, DJ, Struyven, RR, Antaki, F, Chia, MA, Wagner, SK, Jhingan, M, Wu, Z, Guymer, R, Skene, SS, Tammuz, N, Thomson, B, Chopra, R, Keane, PA, Williamson, DJ, Struyven, RR, Antaki, F, Chia, MA, Wagner, SK, Jhingan, M, Wu, Z, Guymer, R, Skene, SS, Tammuz, N, Thomson, B, Chopra, R, and Keane, PA
- Abstract
OBJECTIVE: Recent developments in artificial intelligence (AI) have positioned it to transform several stages of the clinical trial process. In this study, we explore the role of AI in clinical trial recruitment of individuals with geographic atrophy (GA), an advanced stage of age-related macular degeneration, amidst numerous ongoing clinical trials for this condition. DESIGN: Cross-sectional study. SUBJECTS: Retrospective dataset from the INSIGHT Health Data Research Hub at Moorfields Eye Hospital in London, United Kingdom, including 306 651 patients (602 826 eyes) with suspected retinal disease who underwent OCT imaging between January 1, 2008 and April 10, 2023. METHODS: A deep learning model was trained on OCT scans to identify patients potentially eligible for GA trials, using AI-generated segmentations of retinal tissue. This method's efficacy was compared against a traditional keyword-based electronic health record (EHR) search. A clinical validation with fundus autofluorescence (FAF) images was performed to calculate the positive predictive value of this approach, by comparing AI predictions with expert assessments. MAIN OUTCOME MEASURES: The primary outcomes included the positive predictive value of AI in identifying trial-eligible patients, and the secondary outcome was the intraclass correlation between GA areas segmented on FAF by experts and AI-segmented OCT scans. RESULTS: The AI system shortlisted a larger number of eligible patients with greater precision (1139, positive predictive value: 63%; 95% confidence interval [CI]: 54%-71%) compared with the EHR search (693, positive predictive value: 40%; 95% CI: 39%-42%). A combined AI-EHR approach identified 604 eligible patients with a positive predictive value of 86% (95% CI: 79%-92%). Intraclass correlation of GA area segmented on FAF versus AI-segmented area on OCT was 0.77 (95% CI: 0.68-0.84) for cases meeting trial criteria. The AI also adjusts to the distinct imaging criteria from several clinical t
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- 2024
6. The Neural Effects of Extended Practice and the Benefits of a Nap
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Ricci, S., Nelson, A. B., Tatti, E., Panday, P., Lin, J., Thomson, B. O., Chen, H., Tononi, G., Cirelli, C., Ghilardi, M. F., Guglielmelli, Eugenio, Series Editor, Masia, Lorenzo, editor, Micera, Silvestro, editor, Akay, Metin, editor, and Pons, José L., editor
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- 2019
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7. Circulating tumor DNA as a potential marker of adjuvant chemotherapy benefit following surgery for localized pancreatic cancer
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Lee, B., Lipton, L., Cohen, J., Tie, J., Javed, A.A., Li, L., Goldstein, D., Burge, M., Cooray, P., Nagrial, A., Tebbutt, N.C., Thomson, B., Nikfarjam, M., Harris, M., Haydon, A., Lawrence, B., Tai, D.W.M., Simons, K., Lennon, A.M., Wolfgang, C.L., Tomasetti, C., Papadopoulos, N., Kinzler, K.W., Vogelstein, B., and Gibbs, P.
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- 2019
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8. 2.8 Selective Radical Fluorinations
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Bolduc, T. G., additional, Thomson, B., additional, and Sammis, G. M., additional
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- 2021
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9. 19. Oregano essential oil supports sow milk quality and weaning performance of piglets
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Hall, H.N., primary, Bonnick, N., additional, Aarsse, F., additional, and Thomson, B., additional
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- 2023
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10. Short-term changes observed in multiparametric liver MRI following therapy with direct-acting antivirals in chronic hepatitis C virus patients
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Bradley, C., Scott, R. A., Cox, E., Palaniyappan, N., Thomson, B. J., Ryder, S. D., Irving, W. L., Aithal, G. P., Guha, I. N., and Francis, S.
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- 2019
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11. Patterns and Consequences of Stigma Height Variation in a Natural Population of a Distylous Plant, Primula sieboldii
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Nishihiro, J., Washitani, I., Thomson, J. D., and Thomson, B. A.
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- 2000
12. A 4-arm randomized controlled pilot trial of innovative solutions for jugular central venous access device securement in 221 cardiac surgical patients
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Rickard, C.M., Edwards, M., Spooner, A.J., Mihala, G., Marsh, N., Best, J., Wendt, T., Rapchuk, I., Gabriel, S., Thomson, B., Corley, A., and Fraser, J.F.
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- 2016
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13. Global overview of the management of acute cholecystitis during the COVID-19 pandemic (CHOLECOVID study)
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Spiers, H, Kouli, O, Ahmed, W, Varley, R, Ahari, D, Argus, L, Mclean, K, Kamarajah, S, Coe, P, Griffiths, E, Chan, A, Macutkiewicz, C, Jamdar, S, Wilson, M, Fullwood, C, Toogood, G, Gilchrist, A, Goldsworthy, M, Rashid, M, Pockney, P, Varela, J, Brindl, N, Ramirez, J, Marafante, C, Iwao, Y, Ghzawi, A, Elhadi, M, Gacaferi, H, Varghese, C, Adeyeye, A, Alser, O, Teh, C, Prieto, M, Hasan, A, Al-Naggar, H, Salgado, R, Veracierto, F, Lancelotti, T, Solinas, D, Oddi, R, Garcia, F, Mazza Diez, E, Andrade Ramirez, M, Bracco, R, Fernandez, D, Maraschio, M, Obeide, L, Giordano, E, Alcaraz, A, Marani, M, Aguirre, N, Luna, F, Francesconi, M, Chiham, F, Ramos Cossio, R, Alvarez, F, Pantoja Pachajoa, D, Mandojana, F, Merlo, I, Gonzalez, M, Cervelo, G, Puma, R, Vardaro, G, Davis, A, Jurat, D, Guenoff, C, Raubenheimer, K, Goddard, K, Brown, K, Wegrecki, K, Cheung, H, Yang, M, Siddiqui, J, Ahn, J, Huynh, R, Lam, Y, Afzal, M, Ong, B, Chua, M, Ly, K, Thomson, J, Watson, D, Dawson, A, Drane, A, Van Ruyven, S, Lun, E, Ferguson, M, Jeong, J, De Silva, C, Wills, V, Gundara, J, Mccourt, E, Bong, C, Tabone, R, Wong, W, Gray, A, Koh, D, Pollock, M, Singhal, S, Smith, R, Dudi-Venkata, N, Kanhere, H, Stranz, C, Seow, W, Mansour, L, Wormald, J, Loveday, B, Thomson, B, O'Donnell, T, Milenkovski, N, Herath, M, Trochsler, M, Farfus, A, Maddern, G, Bunjo, Z, Kuan, L, Atanasov, G, Samadov, E, Namazov, I, Asgarov, M, Ibrahimli, A, Srinivasan, M, Saeed, M, Aljawder, H, Juma, I, Coimbra, F, Marques, N, Casteleins, W, Petruzziello, A, Jabur, G, Rodriguez, J, Buso, P, Mackenzie, S, Hsiao, M, Sljivic, I, Tecson, A, Karanicolas, P, Roke, R, Moon, J, Butler, E, Riquelme, F, Yanez, M, Catan, F, Uribe, M, Carriel, F, Oppliger, F, Paredes, A, Daroch, D, Aguayo, J, Perez Rivera, C, Acosta Buitrago, L, Kadamani Abiyomaa, A, Mosquera Paz, M, Cabrera, P, Corso, J, Ozcay, N, Ozant, A, Arslan, K, Besim, H, Almezghwi, H, Azzam, A, Bessa, S, El-Sayes, I, Badawy, A, Wael, M, El-Gendi, A, Azab, M, Fayed, M, El Kassas, M, Gamal, M, Tawheed, A, Al Shafie, A, Emile, S, Elfallal, A, Elfeki, H, Shalaby, M, Sakr, A, Elbahnasawy, M, Shama, M, Abdel-Elsalam, W, Abd-Elsalam, S, Escobar Dominguez, J, Medrano, F, Gaitan, S, Escalon Gonzalez, O, Alfaro Varela, J, Cea, M, Interiano, M, Cabrera, B, Lakkis, Z, Georges, P, Antonot, C, Magnin, J, Kamphues, C, Lauscher, J, Schineis, C, Loch, F, Lee, L, Beyer, K, Bouchagier, K, Galanis, I, Bartziotas, D, Lostoridis, E, Tourountzi, P, Nagorni, E, Charalabopoulos, A, Baili, E, Kyros, E, Vagios, I, Skotsimara, A, Liakakos, T, Alexandrou, A, Papalampros, A, Papadopolous, V, Tooulias, A, Kentarchos, I, Christou, C, Tsoulfas, G, Tale-Rosales, L, Lopez Muralles, I, Melendez, H, Bran, G, Monroy Mahecha, F, Contreras, J, Porras, D, Paiz, E, Soto, E, Ixcayau Hernandez, J, Gupta, A, Rajput, D, Kumar, N, Mani, R, Kant, R, Sonkar, A, Anand, A, Agrawal, M, Gaurav, K, Tripathi, M, Sikora, S, Bharathy, K, Kumar Rangapa, M, Khuller, D, Bhojwwani, R, Ayyar, S, Jain, N, Mehraj, A, Hussain, F, Nazir, I, Shah, M, Chowdri, N, Hilmi, A, Argenio, G, Atelli, P, Palladino, E, Armellino, M, Tamini, N, Nespoli, L, Degrate, L, Angrisani, M, Carissimi, F, Bordoni, P, Fleres, F, Clarizia, G, Spolini, A, Franzini, M, Cucinotta, E, Badessi, G, Mazzeo, C, Viscosi, F, Pintabona, G, Campagnaro, T, Poletto, E, Turri, G, Ruzzenente, A, Conci, S, Guglielmi, A, Feo, C, Fabbri, N, Fazzin, M, Giaccari, S, Massani, M, Pelizzo, P, Colella, M, Tutino, R, Cappellacci, F, Medas, F, Canu, G, Erdas, E, Calo, P, Porcu, A, Perra, T, Scanu, A, Fancellu, A, Germani, P, Giunta, C, Biloslavo, A, Abdallah, H, Aizza, G, Barberis, A, Belli, F, Santoliquido, M, Filauro, M, Canonico, G, Nelli, T, Di Martino, C, Capezzuoli, L, Anastasi, A, Bressan, L, Cortinovis, S, Nagliati, C, Colombo, F, Ferrario, L, Bondurri, A, Guerci, C, Maffioli, A, Catena, F, Perrone, G, Giuffrida, M, Morini, A, Annicchiarico, A, Gallo, G, Carpino, A, Ferrari, F, De Paola, G, Sammarco, G, Callari, C, Licari, L, Sorce, V, Di Miceli, D, Lovisetto, F, Zonta, S, Chessa, A, Fiorini, A, De Manzoni Garberini, A, Angelini, E, Moggia, E, Murgese, A, Mungo, S, Birolo, S, Garino, M, Pipitone Federico, N, Muratore, A, Lunghi, E, Calabro, M, Cianci, P, Enrico, R, Capuzzolo, S, Cafagna, L, Minafra, M, Sasia, D, Gattolin, A, Migliore, M, Rimonda, R, Travaglio, E, De Marco, G, Elter, C, Bargellini, T, D'Amico, S, Zambonin, D, Caponi, A, Calini, G, Puggioni, A, Bresadola, V, Zalla, T, Cantafio, S, Feroci, F, Romoli, L, Giudicissi, R, Picciariello, A, Papagni, V, Dibra, R, Altomare, D, Pinotti, E, Montuori, M, Baronio, G, Tonini, V, Sartarelli, L, Gori, A, Cervellera, M, Lapolla, P, Sapienza, P, Brachini, G, Cirillo, B, Zambon, M, Mingoli, A, Pascariello, A, Boccia, L, Benedetti, S, Mantovani, G, De Angelis, M, Ferrara, F, Testa, V, Borghi, F, Maione, F, Pruiti Ciarello, V, Giraudo, G, Agresta, F, Cestaro, G, Prando, D, Cavallo, F, Zese, M, Cillara, N, Sechi, R, Cardia, R, Cannavera, A, Putzu, G, Frongia, F, Pisanu, A, Delogu, D, Esposito, G, Podda, M, Iossa, A, De Angelis, F, Boru, C, Silecchia, G, Palini, G, Garulli, G, Veneroni, S, Tammaro, P, Maida, P, Leake, P, Wanliss, M, Sato, K, Chiyonobu, N, Imamura, H, Yamazaki, S, Watanabe, M, Qasem, A, Ayasra, F, Al Dahabrh, S, Khaled, A, Alsaafin, S, Al-Thunaibat, A, Olaywah, D, Alqudah, S, Alqawasmi, S, Khamees, A, Guboug, A, Es Salim, M, Althwabteh, T, Bani Khaled, H, El-Hammuri, N, Aljesrawi, A, Alamaadany, F, Eljareh, M, Al Gasi, A, Alsaeiti, S, Alkhafeefi, A, Suliaman, T, Alanasri, A, Haroun, A, Haron, A, Kilani, A, Ahmed, M, Alawami, M, Alawami, A, Albashri, M, Abusannuga, M, Malek, A, Jwaili, N, Aldenfria, A, Elzwawi, F, Almugaddami, A, Egdeer, A, Masoud, M, Alazzabi, B, Alezabi, B, Shuwayyah, A, Alkamkhe, A, Aboulqasim, I, Atiyah, H, Alfagi, R, Abdulmula, A, Bouhuwaish, A, Samer, A, Salim, R, Aboazamazem, H, Almiqlash, B, Biala, M, Alganimi, W, Ghamgh, R, Ben Omar, N, Alsoufi, A, Aldreawi, M, Saleim, N, Sowan, F, Saleem, H, Ahmed, A, Samalavicius, N, Aliosin, O, Dailidenas, S, Dulskas, A, Buckus, B, Kuliesius, Z, Bradunaite, R, Dominguez-Rosado, I, Buerba, G, Posadas-Trujillo, O, Alfaro-Goldaracena, A, Cortes, R, Mercado, M, Beristain-Hernandez, J, Mora-Munoz, V, Mena-Bedolla, J, Palacios Ramirez, A, Astorga Medina, M, Van Aert, G, Ombashi, S, Spillenaar Bilgen, R, Vos, D, Besselink, M, Alberts, V, Busch, O, Bemelman, W, Boermeester, M, Daams, F, Gordinou De Gouberville, M, Van Duijvendijk, P, De Graaff, M, Baaij, J, Gans, S, Bos, K, Goudsmit, B, Den Dekker, B, Braat, A, Kuijpers, A, Breukers, S, Borel Rinkes, I, Andel, D, Hayes, T, Carson, D, Bhat, S, Van Der Have, J, Anderson, C, Bissett, I, Windsor, J, Elliott, B, Scowcroft, H, Mclauchlan, J, Ritchie, D, Jeffery, F, Connor, S, Xu, W, Mashlan, H, Thirayan, V, Ly, J, Mcguinness, M, Ferguson, L, Watt, I, Harmston, C, Akinmade, A, Enoch, E, Kayode-Nissi, V, Ogundele, I, Ayoade, B, Adekoya, A, Nwokoro, C, Opadeyi, A, Yusuf, A, Ojajuni, A, Adepoju, O, Muhammad Dauda, M, Keffi Mubarak, M, Lawal, K, Muhammad, D, Salonga, D, Sael, N, Rey, C, Pestano, M, Tan, D, Bangayan, N, Sy, D, Ang, D, Bernardo, E, Chua, J, Alharthi, M, Bukhari, W, Bakier Mohammed, K, Al Athath, S, Ghunaim, M, Saiedi, H, Sultan, N, Farsi, A, Basendowah, M, Malibary, N, Jaloun, H, Altalhi, D, Organjee, A, Moamena, M, Al Zaidi, T, Alyami, M, Alqannas, M, Al-Urfan, M, Elawad, A, Alawadhi, A, Alalawi, Y, Alqarni, A, Alqahtani, B, Alayed, A, Alsobaie, K, Adi, H, Elhaj, M, Dehlawi, A, Behairy, G, Khaled, I, Kmezic, S, Radenkovic, D, Aleksic, L, Markovic, V, Pejovic, I, Antic, A, Kalkan, M, Vujanovic Gadjanski, O, Dusan, S, Marcetic, B, Thiruchelvam, N, Chiow, A, Mun, D, Tan, E, Koh, Y, Loh, W, Wang, Z, Chan, C, Kloppers, C, Almgla, N, Bernon, M, Kahn, M, Karimbocus, N, Roldan Villavicencio, J, Goitia, V, Gutierrez Rios, R, Garcia Ruiz, S, Lopez Deogracias, M, Turrado-Rodriguez, V, Morales, X, Hessheimer, A, Termes Serra, R, Beltran De Heredia, J, Trujillo-Diaz, J, Herreros-Rodriguez, J, Montes-Manrique, M, De Andres-Asenjo, B, Beltran-Heredia, J, Gimenez Maurel, T, Utrilla Fornals, A, Martin Anoro, L, Cortese, S, Perez Diaz, M, Ballon, M, Morote, M, Cebolla Rojas, L, Oliver Guillen, J, Lopez De Fernandez, A, Del Campo Lavilla, M, Mora-Guzman, I, Escartin, A, Pinillos, A, Vela Polanco, F, Jara Quezada, J, Muriel Alvarez, P, Tur-Martinez, J, Camps, J, Herrero, E, Garcia-Domingo, M, Cugat Andorra, E, Crespi Mir, A, Claramonte Bellmunt, O, Vicens Arbona, J, Fernandez Burgos, I, Sarriugarte Lasarte, A, Marin, H, Tellaeche De La Iglesia, M, Ocerin Alganza, O, Salinas Gomez, J, Ramos-Martin, P, Urbieta, A, Nasimi Sabbagh, R, Castell Gomez, J, Serrablo, A, Paterna -Lopez, S, GutiCrossed D SignCopyrightrrez-Diez, M, Abadia-Forcen, M, Serradilla-Martin, M, Duran Munoz-Cruzado, V, Pareja Ciuro, F, Perea Del Pozo, E, Aparicio Sanchez, D, Dios-Barbeito, S, Marenco De La Cuadra, B, Retamar Gentil, M, Reguera-Rosal, J, Infantes Ormad, M, Lopez-Ruiz, J, Landaluce-Olavarria, A, Zevallos-Quiroz, J, Barrutia Leonardo, J, Emaldi, A, Begona, E, Balciscueta Coltell, I, Sebastian, M, Martinez Ramos, S, Martinez Alcaide, S, Lorenzo Perez, J, Martinez Insfran, L, Lopez-Morales, P, Gimenez Frances, C, Rahy-Martin, A, Pelloni, M, Ortiz-Lopez, D, Benet-Munoz, O, Pinero-Gonzalez, L, Alconchel, F, Nicolas-Lopez, T, Rodrigues, K, Cascales Campos, P, Gomez-Bosch, F, Ramirez Romero, P, Ibrahim, M, Hamid, H, Idres, R, Idris, M, Mohammed, O, Ayran, S, Sinan, A, Ozben, V, Aytac, E, Aliyeva, Z, Mutlu, A, Bilgin, I, Karahasanoglu, T, Hamzaoglu, I, Bozkirli, B, Uprak, T, Kotan, T, Coskun, M, Kara, Y, Somuncu, E, Kocatas, A, Bozkurt, M, Demirli Atici, S, Kaya, T, Sert, I, Emiroglu, M, Jaffar, M, Younis, M, Aziz, T, Ikram, F, Sandal, M, Al Madhloum Al Suwaidi, F, Alshaikh, M, Saber, A, Khammas, A, Nessa, A, Jardine, R, Nicol, L, Clark, C, Mcgee, A, Alkari, B, Feretis, M, Antakia, R, Georgiades, F, Moneim, J, O'Neill, R, Balakrishnan, A, Lunevicius, R, Sud, A, Moutsos, I, Gomez, D, Shahid, S, Majeed, T, Ibrahim, W, Kadum, K, Melia, R, Magee, C, Chicken, D, Kumar, S, Alshibshoubi, M, Van Laarhoven, S, Dewi, F, Williams, J, Byrne, B, Wilkerson, P, Tang, C, Farhangmehr, N, Jonas, A, Charavanamuttu, V, Almeida, K, Efthimiou, E, Boardley, J, White, A, Butt, M, Menzies, D, Gundkalli, Z, Hassanzadeh-Baboli, D, Jones, O, Mistry, P, Saha, S, Gerrard, A, Evans, J, Rajeev, S, Ali, W, Ross, E, Gilliam, A, Hitchins, C, Emslie, K, Spellar, K, Sked, H, Briggs, C, Brown, L, A Hemadasa, N, Apollos, J, Belgaumkar, A, Tawfik, A, Brewin, L, Oyewole, B, Wadhawan, H, Massie, E, Rutherford, D, Mcgivern, K, Mcelroy, L, De'Ath, H, Tobbal, M, Nagendram, S, Patel, P, Handa, S, Houghton, G, Sundaralingam, S, Parker, J, Morgan, R, Gala, T, Ibrahim, S, Harby, R, Abdelkarim, M, Holroyd, D, Thomas, R, Mclennan, E, Boardley, R, Jamieson, N, Ebied, H, Gossage, J, Davies, A, Wheatstone, S, Jawad, Z, Jiao, L, Rajagopal, P, Sodergren, M, Lami, M, Wiberg, A, Bond-Smith, G, Gemmill, E, Lenzi, E, Sapre, D, Herrod, P, Boyd-Carson, H, Garcea, G, Issa, E, Jackson, A, Fashina, T, Pan, H, Farquharson, B, Shafiq, H, Emanuel, O, Mahdi, S, Jeyarajah, S, Finch, L, Whiting, G, Pigott, L, Martin, J, Siriwardena, A, Beatson, K, Abawi, L, Lam, W, Rea, W, Andrews, B, Al-Sarireh, B, Soliman, F, Burridge, J, Jenvey, C, Hammoda, M, Hollyman, M, Merker, L, Richards, J, Sukumaran, V, Rogers, S, Payne, C, Bibi, S, Raza, K, Ul Ain, N, Dronamraju, S, Patil, S, Nachimuthu, S, Ravindran, S, Patel, S, Ivanov, B, Patel, M, Ejtehadi, F, Jebamani, J, Akhter Rahman, M, Woodun, H, De Prendergast, A, Afzal, A, Bota, E, Abdul, S, Karmarkar, R, Crockett, E, Evans, L, Appleton, B, Dada, O, Kulkarni, R, Albirnawi, H, Gravestock, P, Vincenti, C, Taribagil, S, Dent, B, Tse, C, Clayton, B, Burdekin, E, Bannister, L, Alam, I, Gray, J, Mactier, M, Pollock, A, Gough, V, Kanchustambam, S, Ridgway, M, Arujunan, K, Gopalswamy, S, Monteiro De Barros, J, Lyons, T, Griffith, D, Awan, A, Latif, J, Bandlamudi, N, Bhatti, I, Raptis, D, Machairas, N, Pissanou, T, Mestre-Costa, J, Hidalgo Salinas, C, Pollok, J, Al-Ardah, M, Watson-Jones, E, Rontree-Carey, T, Boyce, T, Hawkin, P, Elmaradny, A, Ross, K, Adu-Peprah, E, Pinto, K, Dunne, D, Mccready, R, Nita, G, Szatmary, P, Tay, V, Rajput, K, Rajendran, I, Chaudhury, M, Zambas, G, Swaminathan, C, Atif, Q, Barrow, T, Williams, O, Malik, A, Conroy, S, Lindley, S, Gilmore, K, Boden, E, Richards, S, Hraishawi, I, Polak, P, Mclaughlin, D, Deeny, D, Shuttleworth, R, Harris, A, Peilober-Richardson, A, Morris, G, Sara, X, Almourad, H, Ang, Y, Smyth, R, Ding, D, Foster, J, Bond, A, Kumar, Y, Ahmad, A, Radoi, D, Alkaili-Alyamani, A, Balakrishnan, S, Satchidanand, R, Danwaththa Liyanage, A, Blake, I, Ransome, M, Weerasinghe, C, Kenington, C, Mayo, K, Mohammed, M, Cockbain, A, Peckham-Cooper, A, Mccauley, G, Gordon, C, Smith, A, Hawkins, W, Chakravartty, S, Baillie, C, Kenny, R, Kumar, A, Koimtzis, G, Bellamy, E, Menon, A, Kanakala, A, Nevins, E, Madhavan, A, Thulasiraman, S, France, K, 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C., Sara X., Almourad H., Ang Y., Smyth R., Ding D., Foster J., Bond A., Kumar Y., Ahmad A., Radoi D., Alkaili-Alyamani A., Balakrishnan S., Satchidanand R. Y., Danwaththa Liyanage A. S., Blake I., Ransome M., Weerasinghe C., Kenington C., Mayo K., Mohammed M., Cockbain A. J., Peckham-Cooper A., McCauley G., Gordon C., Smith A., Hawkins W., Chakravartty S., Baillie C., Kenny R., Kumar A., Koimtzis G., Bellamy E., Menon A., Kanakala A., Nevins E. J., Madhavan A., Thulasiraman S., France K., O'Connor A., Idama D., Raslan C., Sridhar S., Parveen M., Mubashar T., Jarvis S., Cakmak I., Wright C., Andrews S., Abdelsaid K Abdul Aal Y., Jayasankar B., Morilla J., Shehata M., Subba N., Tewari N., El-Sayed C., Somaie D., Beheiry N., Douka E., Arumugam S., Wijetunga I., Leivers E., Ibrahim B., Khan K., Wheat J., Christopher J., Barnett R., Elberm H., Booker J., Ashai S., Berry D., Luhmann A., Sgro A., Rashid M. 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V. M., Kouli O., Ahmed W. U., Varley R., Ahari D., Argus L., McLean K. A., Kamarajah S. K., Coe P., Griffiths E. A., Chan A. K. C., Macutkiewicz C., Jamdar S., Wilson M., Fullwood C., Toogood G., McLean K., Ahmed W., Gilchrist A., Goldsworthy M., Rashid M., Pockney P., Varela J., Brindl N., Ramirez J., Marafante C., Iwao Y., Ghzawi A., Elhadi M., Gacaferi H., Varghese C., Adeyeye A., Alser O., Teh C., Prieto M., Hasan A., Al-Naggar H., Salgado R., Veracierto F., Lancelotti T., Solinas D., Oddi R., Garcia F. W., Mazza Diez E., Andrade Ramirez M. R., Bracco R., Fernandez D., Maraschio M. A., Obeide L., Giordano E., Alcaraz A., Marani M. A., Aguirre N., Luna F., Francesconi M., Chiham F., Ramos Cossio R., Alvarez F. A., Pantoja Pachajoa D. A., Mandojana F., Merlo I. G., Gonzalez M. H., Cervelo G., Puma R., Vardaro G. F., Davis A., Jurat D., Guenoff C., Raubenheimer K., Goddard K., Brown K., Wegrecki K. J., Cheung H. Y. C., Yang M., Cheung H., Siddiqui J., Ahn J. H., Huynh R., Lam Y. H., Afzal M., Ong B. S., Chua M. Y. M., Ly K., Thomson J. E., Watson D., Dawson A. C., Drane A., Van Ruyven S., Lun E. W. Y., Ferguson M., Jeong J. Y., De Silva C., Wills V., Gundara J., McCourt E., Bong C., Tabone R., Wong W. J., Gray A., Koh D., Pollock M., Singhal S., Smith R., Dudi-Venkata N. N., Kanhere H., Stranz C., Seow W., Mansour L. T., Wormald J., Loveday B. P. T., Thomson B., O'Donnell T., Milenkovski N., Herath M., Trochsler M., Farfus A., Maddern G., Bunjo Z., Kuan L. L., Atanasov G., Dawson A., Lun E., Samadov E., Namazov I., Asgarov M., Ibrahimli A., Srinivasan M., Saeed M. F., Aljawder H., Juma I., Coimbra F. J., Marques N., Casteleins W. A., Petruzziello A., Jabur G., Rodriguez J. F. P., Buso P. L., Mackenzie S., Hsiao M., Sljivic I., Tecson A., Karanicolas P. J., Roke R., Moon J., Butler E. V., Riquelme F., Yanez M., Catan F., Uribe M., Carriel F., Oppliger F., Paredes A., Daroch D., Aguayo J. C., Perez Rivera C. J., Acosta Buitrago L. M., Kadamani Abiyomaa A., Mosquera Paz M. S., Cabrera P., Corso J., Ozcay N., Ozant A., Arslan K., Besim H., Almezghwi H., Azzam A. Y., Bessa S., El-Sayes I., Badawy A., Wael M., El-Gendi A., Azab M. A., Fayed M., El Kassas M., Gamal M., Tawheed A., Al Shafie A., Emile S., Elfallal A., Elfeki H., Shalaby M., Sakr A., Elbahnasawy M., Shama M., Abdel-Elsalam W., Abd-Elsalam S., Escobar Dominguez J. E., Medrano F., Gaitan S., Escalon Gonzalez O. M., Alfaro Varela J. C., Cea M., Interiano M., Cabrera B., Lakkis Z., Georges P., Antonot C., Magnin J., Kamphues C., Lauscher J. C., Schineis C., Loch F. N., Lee L. D., Beyer K., Bouchagier K., Galanis I., Bartziotas D., Lostoridis E., Tourountzi P., Nagorni E. A., Charalabopoulos A., Baili E., Kyros E., Vagios I., Skotsimara A., Liakakos T., Alexandrou A., Papalampros A., Papadopolous V., Tooulias A., Kentarchos I., Christou C., Tsoulfas G., Tale-Rosales L. F., Lopez Muralles I., Melendez H., Bran G., Monroy Mahecha F. A., Contreras J. R., Porras D. E., Paiz E., Soto E. R., Ixcayau Hernandez J. R., Gupta A., Rajput D., Kumar N., Mani R., Kant R., Sonkar A. A., Anand A., Agrawal M. K., Gaurav K., Tripathi M., Sikora S., Bharathy K., Kumar Rangapa M., Khuller D. S., Bhojwwani R., Ayyar S., Jain N., Mehraj A., Hussain F., Nazir I., Shah M., Chowdri N. A., Hilmi A., Argenio G., Atelli P., Palladino E., Armellino M. F., Tamini N., Nespoli L. C., Degrate L., Angrisani M., Carissimi F., Bordoni P., Fleres F., Clarizia G., Spolini A., Franzini M., Cucinotta E., Badessi G., Mazzeo C., Viscosi F., Pintabona G., Campagnaro T., Poletto E., Turri G., Ruzzenente A., Conci S., Guglielmi A., Feo C., Fabbri N., Fazzin M., Giaccari S., Feo C. V., Massani M., Pelizzo P., Colella M., Tutino R., Cappellacci F., Medas F., Canu G. L., Erdas E., Calo P. G., Porcu A., Perra T., Scanu A. M., Feo C. F., Fancellu A., Germani P., Giunta C., Biloslavo A., Abdallah H., Aizza G., Barberis A., Belli F., Santoliquido M., Filauro M., Canonico G., Nelli T., Di Martino C., Capezzuoli L., Anastasi A., Bressan L., Cortinovis S., Nagliati C., Colombo F., Ferrario L., Bondurri A., Guerci C., Maffioli A., Catena F., Perrone G., Giuffrida M., Morini A., Annicchiarico A., Gallo G., Carpino A., Ferrari F., De Paola G., Sammarco G., Callari C., Licari L., Sorce V., Di Miceli D., Lovisetto F., Zonta S., Chessa A., Fiorini A., De Manzoni Garberini A., Angelini E., Moggia E., Murgese A., Mungo S., Birolo S. L., Garino M., Pipitone Federico N. S., Muratore A., Lunghi E. G., Calabro M., Cianci P., Enrico R., Capuzzolo S., Cafagna L., Minafra M., Sasia D., Gattolin A., Migliore M., Rimonda R., Travaglio E., De Marco G., Elter C., Bargellini T., D'Amico S., Zambonin D., Caponi A., Calini G., Puggioni A., Bresadola V., Zalla T., Cantafio S., Feroci F., Romoli L., Giudicissi R., Picciariello A., Papagni V., Dibra R., Altomare D. F., Pinotti E., Montuori M., Baronio G., Tonini V., Sartarelli L., Gori A., Cervellera M., Lapolla P., Sapienza P., Brachini G., Cirillo B., Zambon M., Mingoli A., Pascariello A., Boccia L., Benedetti S., Mantovani G., De Angelis M., Ferrara F., Testa V., Borghi F., Maione F., Pruiti Ciarello V., Giraudo G., Agresta F., Cestaro G., Prando D., Cavallo F., Zese M., Cillara N., Sechi R., Cardia R., Cannavera A., Putzu G., Frongia F., Pisanu A., Delogu D., Esposito G., Podda M., Iossa A., De Angelis F., Boru C., Silecchia G., Palini G. M., Garulli G., Veneroni S., Tammaro P., Maida P., Leake P. A., Wanliss M. G., Sato K., Chiyonobu N., Imamura H., Yamazaki S., Watanabe M., Qasem A., Ayasra F., Al Dahabrh S., Khaled A., Alsaafin S., Al-Thunaibat A., Olaywah D., Alqudah S., Alqawasmi S., Khamees A., Guboug A., Es Salim M., Althwabteh T., Bani Khaled H., El-Hammuri N., Aljesrawi A., Alamaadany F., Eljareh M., Al Gasi A. E. J., Alsaeiti S., Alkhafeefi A. S., Suliaman T., Alanasri A. H. A., Haroun A. B. A., Haron A., Kilani A. I., Ahmed M., Alawami M., Alawami A., Albashri M., Abusannuga M., Malek A., Jwaili N., Aldenfria A., Elzwawi F., Almugaddami A., Egdeer A. S. A., Masoud M., Alazzabi B., Alezabi B., Shuwayyah A., Alkamkhe A. A. S., Aboulqasim I., Atiyah H., Alfagi R. A. A., Abdulmula A., Bouhuwaish A., Samer A., Salim R., Aboazamazem H., Almiqlash B., Biala M., Alganimi W., Ghamgh R., Ben Omar N., Alsoufi A., Aldreawi M., Saleim N., Sowan F., Saleem H., Ahmed A., Samalavicius N. E., Aliosin O., Dailidenas S., Dulskas A., Buckus B., Kuliesius Z., Bradunaite R., Dominguez-Rosado I., Buerba G. A., Posadas-Trujillo O. E., Alfaro-Goldaracena A., Cortes R., Mercado M. A., Beristain-Hernandez J. L., Mora-Munoz V. S., Mena-Bedolla J. M., Palacios Ramirez A. R., Astorga Medina M. M., Van Aert G., Ombashi S., Spillenaar Bilgen R., Vos D., Besselink M., Alberts V., Busch O., Bemelman W., Boermeester M., Daams F., Gordinou De Gouberville M., Van Duijvendijk P., De Graaff M., Baaij J., Gans S., Bos K., Goudsmit B., Den Dekker B., Braat A., Kuijpers A., Breukers S., Borel Rinkes I., Andel D., Hayes T., Carson D., Bhat S., Van Der Have J., Anderson C., Bissett I., Windsor J., Elliott B. M., Scowcroft H., McLauchlan J., Ritchie D., Jeffery F., Connor S., Xu W., Mashlan H., Thirayan V., Ly J., McGuinness M. J., Ferguson L., Watt I., Harmston C., Akinmade A., Enoch E., Kayode-Nissi V., Ogundele I., Ayoade B. A., Adekoya A., Nwokoro C., Opadeyi A., Yusuf A., Ojajuni A., Adepoju O., Muhammad Dauda M., Keffi Mubarak M., Lawal K., Muhammad D., Salonga D., Sael N. A., Rey C. M., Pestano M., Tan D., Bangayan N. R., Sy D. K., Ang D., Bernardo E., Chua J. P., Alharthi M., Bukhari W., Bakier Mohammed K., Al Athath S., Ghunaim M., Saiedi H., Sultan N., Farsi A., Basendowah M., Malibary N., Jaloun H., Altalhi D., Organjee A., Moamena M., Al Zaidi T. M., Alyami M., Alqannas M., Al-Urfan M., Elawad A., Alawadhi A., Alalawi Y., Alqarni A., Alqahtani B., Alayed A., Alsobaie K., Adi H., Elhaj M., Dehlawi A., Behairy G., Khaled I., Kmezic S., Radenkovic D., Aleksic L., Markovic V., Pejovic I., Antic A., Kalkan M., Vujanovic Gadjanski O., Dusan S., Marcetic B., Thiruchelvam N., Chiow A. K. H., Lee L. S., Mun D. Y. C., Tan E. K., Koh Y. X., Loh W. L., Wang Z., Chan C. Y., Kloppers C., Almgla N., Bernon M., Kahn M., Karimbocus N., Roldan Villavicencio J. I., Goitia V., Gutierrez Rios R. D., Garcia Ruiz S., Lopez Deogracias M., Turrado-Rodriguez V., Morales X., Hessheimer A., Termes Serra R., Beltran De Heredia J., Trujillo-Diaz J., Herreros-Rodriguez J., Montes-Manrique M., De Andres-Asenjo B., Beltran-Heredia J., Gimenez Maurel T., Utrilla Fornals A., Martin Anoro L. F., Cortese S., Perez Diaz M. D., Ballon M., Morote M., Cebolla Rojas L., Oliver Guillen J. R., Lopez De Fernandez A., Del Campo Lavilla M., Mora-Guzman I., Escartin A., Pinillos A., Vela Polanco F. F., Jara Quezada J. H., Muriel Alvarez P., Tur-Martinez J., Camps J., Herrero E., Garcia-Domingo M. I., Cugat Andorra E., Crespi Mir A., Claramonte Bellmunt O., Vicens Arbona J. C., Fernandez Burgos I. R., Sarriugarte Lasarte A., Marin H., Tellaeche De La Iglesia M., Ocerin Alganza O., Salinas Gomez J., Ramos-Martin P., Urbieta A., Nasimi Sabbagh R., Castell Gomez J. T., Serrablo A., Paterna -Lopez S., GutiCrossed D SignCopyrightrrez-Diez M., Abadia-Forcen M. T., Serradilla-Martin M., Duran Munoz-Cruzado V. M., Pareja Ciuro F., Perea Del Pozo E., Aparicio Sanchez D., Dios-Barbeito S., Marenco De La Cuadra B., Retamar Gentil M., Reguera-Rosal J., Infantes Ormad M., Lopez-Ruiz J. A., Landaluce-Olavarria A., Zevallos-Quiroz J. C., Barrutia Leonardo J., Emaldi A., Begona E., Balciscueta Coltell I., Sebastian M., Martinez Ramos S., Martinez Alcaide S., Lorenzo Perez J., Martinez Insfran L. A., Lopez-Morales P., Gimenez Frances C., Rahy-Martin A., Pelloni M., Ortiz-Lopez D., Benet-Munoz O., Pinero-Gonzalez L., Alconchel F., Nicolas-Lopez T., Rodrigues K., Cascales Campos P. A., Gomez-Bosch F., Ramirez Romero P., Ibrahim M., Hamid H. K. S., Idres R., Idris M., Mohammed O., Ayran S., Sinan A. H., Ozben V., Aytac E., Aliyeva Z., Mutlu A. U., Bilgin I. A., Karahasanoglu T., Hamzaoglu I., Bozkirli B., Uprak T. K., Kotan T., Coskun M., Kara Y., Somuncu E., Kocatas A., Bozkurt M. A., Demirli Atici S., Kaya T., Sert I., Emiroglu M., Jaffar M., Younis M. U., Aziz T., Ikram F., Sandal M., Al Madhloum Al Suwaidi F., Alshaikh M. O., Saber A., Khammas A., Nessa A., Jardine R., Nicol L., Clark C., McGee A., Alkari B., Feretis M., Antakia R., Georgiades F., Moneim J., O'Neill R., Balakrishnan A., Lunevicius R., Sud A., Moutsos I., Gomez D., Shahid S., Majeed T., Ibrahim W. K. G., Kadum K., Melia R., Magee C., Chicken D. W., Kumar S., Alshibshoubi M., Van Laarhoven S., Dewi F., Williams J., Byrne B., Wilkerson P., Tang C. B., Farhangmehr N., Jonas A., Charavanamuttu V., Almeida K., Efthimiou E., Boardley J., White A., Butt M. A., Menzies D., Gundkalli Z., Hassanzadeh-Baboli D., Jones O., Mistry P., Saha S., Gerrard A., Evans J., Rajeev S., Ali W., Ross E., Gilliam A., Hitchins C., Emslie K., Spellar K., Sked H., Briggs C., Brown L., A Hemadasa N., Apollos J. R., Belgaumkar A., Tawfik A., Brewin L., Oyewole B., Wadhawan H., Massie E., Rutherford D., McGivern K., McElroy L., De'Ath H. D., Tobbal M., Nagendram S., Patel P., Handa S., Houghton G., Sundaralingam S. S., Parker J., Morgan R., Gala T., Ibrahim S., Harby R., Abdelkarim M., Holroyd D., Thomas R., McLennan E., Boardley R., Jamieson N. B., Ebied H., Gossage J., Davies A., Wheatstone S., Jawad Z., Jiao L., Rajagopal P., Sodergren M., Lami M., Wiberg A., Bond-Smith G., Gemmill E., Lenzi E., Sapre D., Herrod P., Boyd-Carson H., Garcea G., Issa E., Jackson A., Fashina T., Pan H., Farquharson B., Shafiq H., Emanuel O., Mahdi S., Jeyarajah S., Finch L., Whiting G., Pigott L., Martin J., Siriwardena A. K., Beatson K., Abawi L., Lam W., Rea W., Andrews B., Al-Sarireh B., Soliman F., Burridge J., Jenvey C., Hammoda M., Hollyman M., Merker L., Richards J., Sukumaran V., Rogers S., Payne C., Bibi S., Raza K., Ul Ain N., Dronamraju S., Patil S., Nachimuthu S., Ravindran S., Patel S., Ivanov B., Patel M., Ejtehadi F., Jebamani J., Akhter Rahman M. M., Woodun H., De Prendergast A., Afzal A., Bota E., Abdul S. R., Karmarkar R., Crockett E., Evans L., Appleton B., Griffiths E., Dada O., Kulkarni R., Albirnawi H., Gravestock P., Vincenti C., Taribagil S., Dent B., Tse C., Clayton B., Burdekin E., Bannister L., Alam I., Gray J., Mactier M., Pollock A., Gough V., Kanchustambam S. R., Ridgway M., Arujunan K., Gopalswamy S., Monteiro De Barros J., Lyons T., Griffith D., Awan A. K., Latif J., Bandlamudi N., Bhatti I., Raptis D. A., Machairas N., Pissanou T., Mestre-Costa J., Hidalgo Salinas C., Pollok J. M., Al-Ardah M., Watson-Jones E., Rontree-Carey T., Boyce T., Hawkin P., Elmaradny A., Ross K., Adu-Peprah E., Pinto K., Dunne D., McCready R., Nita G., Szatmary P., Tay V. L., Rajput K., Rajendran I., Chaudhury M., Zambas G., Swaminathan C., Atif Q. A. A., Barrow T., Williams O., Malik A., Conroy S., Lindley S., Gilmore K., Boden E., Richards S. K., Hraishawi I., Polak P., McLaughlin D., Deeny D., Shuttleworth R., Harris A., Peilober-Richardson A., Morris G. C., Sara X., Almourad H., Ang Y., Smyth R., Ding D., Foster J., Bond A., Kumar Y., Ahmad A., Radoi D., Alkaili-Alyamani A., Balakrishnan S., Satchidanand R. Y., Danwaththa Liyanage A. S., Blake I., Ransome M., Weerasinghe C., Kenington C., Mayo K., Mohammed M., Cockbain A. J., Peckham-Cooper A., McCauley G., Gordon C., Smith A., Hawkins W., Chakravartty S., Baillie C., Kenny R., Kumar A., Koimtzis G., Bellamy E., Menon A., Kanakala A., Nevins E. J., Madhavan A., Thulasiraman S., France K., O'Connor A., Idama D., Raslan C., Sridhar S., Parveen M., Mubashar T., Jarvis S., Cakmak I., Wright C., Andrews S., Abdelsaid K Abdul Aal Y., Jayasankar B., Morilla J., Shehata M., Subba N., Tewari N., El-Sayed C., Somaie D., Beheiry N., Douka E., Arumugam S., Wijetunga I., Leivers E., Ibrahim B., Khan K., Wheat J., Christopher J., Barnett R., Elberm H., Booker J., Ashai S., Berry D., Luhmann A., Sgro A., Rashid M. M., Galea M., Jeyakumar J., Marriott P., Zafar S., Baker A., Yershov D., Galanopoulos G., Jordan R., Peinado Garcia C., Anyaugo N., Bath M. F., Omatseye J., Roberts L., Argyriou E. O., Machesney M., Parmar C., Clark S., Khalil H., Unsworth S., Mlotshwa M., Ayoub N., Aboelkhair A., Iosif E., Mohamed N., Reynolds E., Mackender E., Robinson D., Mufti W., Fischkoff K., Coleman N., Anantha Sathyanarayana S., Deutsch G., Giangola M., Lin D., Weiss M., Chung C., Nguyen A., Mueller J., Dabit M., Gordon J., McGuire E., Rashid O., Georgi E., Gallo M., Kunstman J. W., Peters N. V., O'Connor R., Bhattacharya B., Onkendi E., Santos A. P., Richmond R., Warren M., Zhang K., Broderick R., Clary B., Horgan S., Doucet J., Liepert A., Harmon L., McCall C., Sham J. G., Williams E., Labadie K. P., Clark N. M., Dickerson L. K., Hammill C. W., Williams G., Kushner B., Cos H., Zarate Rodriguez J., Bailey K., Al-Raimi I. M. 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- Abstract
https://www.scopus.com/record/display.uri?eid=2-s2.0-85138595712&origin=inward&txGid=728c82ff11b9726b5d443216a91e7ffa#:~:text=Background: This study,of this pandemic.
- Published
- 2022
14. Use and outcomes from neoadjuvant chemotherapy in borderline resectable pancreatic ductal adenocarcinoma in an Australasian population
- Author
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Walpole, I, Lee, B, Shapiro, J, Thomson, B, Lipton, L, Ananda, S, Usatoff, V, Mclachlan, S-A, Knowles, B, Fox, A, Wong, R, Cooray, P, Burge, M, Clarke, K, Pattison, S, Nikfarjam, M, Tebbutt, N, Harris, M, Nagrial, A, Zielinski, R, Chee, CE, Gibbs, P, Walpole, I, Lee, B, Shapiro, J, Thomson, B, Lipton, L, Ananda, S, Usatoff, V, Mclachlan, S-A, Knowles, B, Fox, A, Wong, R, Cooray, P, Burge, M, Clarke, K, Pattison, S, Nikfarjam, M, Tebbutt, N, Harris, M, Nagrial, A, Zielinski, R, Chee, CE, and Gibbs, P
- Abstract
Background: Use of neoadjuvant (NA) chemotherapy is recommended when pancreatic ductal adenocarcinoma (PDAC) is borderline resectable. Method: A retrospective analysis of consecutive patients with localized PDAC between January 2016 and March 2019 within the Australasian Pancreatic Cancer Registry (PURPLE, Pancreatic cancer: Understanding Routine Practice and Lifting End results) was performed. Clinicopathological characteristics, treatment, and outcome were analyzed. Overall survival (OS) comparison was performed using log-rank model and Kaplan–Meier analysis. Results: The PURPLE database included 754 cases with localised PDAC, including 148 (20%) cases with borderline resectable pancreatic cancer (BRPC). Of the 148 BRPC patients, 44 (30%) underwent immediate surgery, 80 (54%) received NA chemotherapy, and 24 (16%) were inoperable. The median age of NA therapy patients was 63 years and FOLFIRINOX (53%) was more often used as NA therapy than gemcitabine/nab-paclitaxel (31%). Patients who received FOLFIRINOX were younger than those who received gemcitabine/nab-paclitaxel (60 years vs. 67 years, p =.01). Surgery was performed in 54% (43 of 80) of BRPC patients receiving NA chemotherapy, with 53% (16 of 30) achieving R0 resections. BRPC patients undergoing surgery had a median OS of 30 months, and 38% (9 of 24) achieved R0 resection. NA chemotherapy patients had a median OS of 20 months, improving to 24 months versus 10 months for patients receiving FOLFIRINOX compared to gemcitabine/nab-paclitaxel (Hazard Ratio (HR).3, p <.0001). Conclusions: NA chemotherapy use in BRPC is increasing in Australia. One half of patients receiving NA chemotherapy proceed to curative resection, with 53% achieving R0 resections. Patients receiving Infusional 5-flurouracil, Irinotecan and Oxaliplatin (FOLIRINOX) had increased survival than gemcitabine/nab-paclitaxel. Treatment strategies are being explored in the MASTERPLAN and DYNAMIC-Pancreas trials.
- Published
- 2023
15. Three new species of Euphorbia L. subgenus Chamaesyce Rafinesque (Euphorbiaceae) from central and northern Australia
- Author
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Thomson, B G and BioStor
- Published
- 1992
16. Global overview of the management of acute cholecystitis during the COVID-19 pandemic (CHOLECOVID study)
- Author
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Spiers H. V. M., Kouli O., Ahmed W. U., Varley R., Ahari D., Argus L., McLean K. A., Kamarajah S. K., Coe P., Griffiths E. A., Chan A. K. C., Macutkiewicz C., Jamdar S., Wilson M., Fullwood C., Toogood G., McLean K., Ahmed W., Gilchrist A., Goldsworthy M., Rashid M., Pockney P., Varela J., Brindl N., Ramirez J., Marafante C., Iwao Y., Ghzawi A., Elhadi M., Gacaferi H., Varghese C., Adeyeye A., Alser O., Teh C., Prieto M., Hasan A., Al-Naggar H., Salgado R., Veracierto F., Lancelotti T., Solinas D., Oddi R., Garcia F. W., Mazza Diez E., Andrade Ramirez M. R., Bracco R., Fernandez D., Maraschio M. A., Obeide L., Giordano E., Alcaraz A., Marani M. A., Aguirre N., Luna F., Francesconi M., Chiham F., Ramos Cossio R., Alvarez F. A., Pantoja Pachajoa D. A., Mandojana F., Merlo I. G., Gonzalez M. H., Cervelo G., Puma R., Vardaro G. F., Davis A., Jurat D., Guenoff C., Raubenheimer K., Goddard K., Brown K., Wegrecki K. J., Cheung H. Y. C., Yang M., Cheung H., Siddiqui J., Ahn J. H., Huynh R., Lam Y. H., Afzal M., Ong B. S., Chua M. Y. M., Ly K., Thomson J. E., Watson D., Dawson A. C., Drane A., Van Ruyven S., Lun E. W. Y., Ferguson M., Jeong J. Y., De Silva C., Wills V., Gundara J., McCourt E., Bong C., Tabone R., Wong W. J., Gray A., Koh D., Pollock M., Singhal S., Smith R., Dudi-Venkata N. N., Kanhere H., Stranz C., Seow W., Mansour L. T., Wormald J., Loveday B. P. T., Thomson B., O'Donnell T., Milenkovski N., Herath M., Trochsler M., Farfus A., Maddern G., Bunjo Z., Kuan L. L., Atanasov G., Dawson A., Lun E., Samadov E., Namazov I., Asgarov M., Ibrahimli A., Srinivasan M., Saeed M. F., Aljawder H., Juma I., Coimbra F. J., Marques N., Casteleins W. A., Petruzziello A., Jabur G., Rodriguez J. F. P., Buso P. L., Mackenzie S., Hsiao M., Sljivic I., Tecson A., Karanicolas P. J., Roke R., Moon J., Butler E. V., Riquelme F., Yanez M., Catan F., Uribe M., Carriel F., Oppliger F., Paredes A., Daroch D., Aguayo J. C., Perez Rivera C. J., Acosta Buitrago L. M., Kadamani Abiyomaa A., Mosquera Paz M. S., Cabrera P., Corso J., Ozcay N., Ozant A., Arslan K., Besim H., Almezghwi H., Azzam A. Y., Bessa S., El-Sayes I., Badawy A., Wael M., El-Gendi A., Azab M. A., Fayed M., El Kassas M., Gamal M., Tawheed A., Al Shafie A., Emile S., Elfallal A., Elfeki H., Shalaby M., Sakr A., Elbahnasawy M., Shama M., Abdel-Elsalam W., Abd-Elsalam S., Escobar Dominguez J. E., Medrano F., Gaitan S., Escalon Gonzalez O. M., Alfaro Varela J. C., Cea M., Interiano M., Cabrera B., Lakkis Z., Georges P., Antonot C., Magnin J., Kamphues C., Lauscher J. C., Schineis C., Loch F. N., Lee L. D., Beyer K., Bouchagier K., Galanis I., Bartziotas D., Lostoridis E., Tourountzi P., Nagorni E. A., Charalabopoulos A., Baili E., Kyros E., Vagios I., Skotsimara A., Liakakos T., Alexandrou A., Papalampros A., Papadopolous V., Tooulias A., Kentarchos I., Christou C., Tsoulfas G., Tale-Rosales L. F., Lopez Muralles I., Melendez H., Bran G., Monroy Mahecha F. A., Contreras J. 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Belli F., Santoliquido M., Filauro M., Canonico G., Nelli T., Di Martino C., Capezzuoli L., Anastasi A., Bressan L., Cortinovis S., Nagliati C., Colombo F., Ferrario L., Bondurri A., Guerci C., Maffioli A., Catena F., Perrone G., Giuffrida M., Morini A., Annicchiarico A., Gallo G., Carpino A., Ferrari F., De Paola G., Sammarco G., Callari C., Licari L., Sorce V., Di Miceli D., Lovisetto F., Zonta S., Chessa A., Fiorini A., De Manzoni Garberini A., Angelini E., Moggia E., Murgese A., Mungo S., Birolo S.L., Garino M., Pipitone Federico N.S., Muratore A., Lunghi E.G., Calabro M., Cianci P., Enrico R., Capuzzolo S., Cafagna L., Minafra M., Sasia D., Gattolin A., Migliore M., Rimonda R., Travaglio E., De Marco G., Elter C., Bargellini T., D'Amico S., Zambonin D., Caponi A., Calini G., Puggioni A., Bresadola V., Zalla T., Cantafio S., Feroci F., Romoli L., Giudicissi R., Picciariello A., Papagni V., Dibra R., Altomare D.F., Pinotti E., Montuori M., Baronio G., Tonini V., Sartarelli L., Gori A., Cervellera M., Lapolla P., Sapienza P., Brachini G., Cirillo B., Zambon M., Mingoli A., Pascariello A., Boccia L., Benedetti S., Mantovani G., De Angelis M., Ferrara F., Testa V., Borghi F., Maione F., Pruiti Ciarello V., Giraudo G., Agresta F., Cestaro G., Prando D., Cavallo F., Zese M., Cillara N., Sechi R., Cardia R., Cannavera A., Putzu G., Frongia F., Pisanu A., Delogu D., Esposito G., Podda M., Iossa A., De Angelis F., Boru C., Silecchia G., Palini G.M., Garulli G., Veneroni S., Tammaro P., Maida P., Leake P.A., Wanliss M.G., Sato K., Chiyonobu N., Imamura H., Yamazaki S., Watanabe M., Qasem A., Ayasra F., Al Dahabrh S., Khaled A., Alsaafin S., Al-Thunaibat A., Olaywah D., Alqudah S., Alqawasmi S., Khamees A., Guboug A., Es Salim M., Althwabteh T., Bani Khaled H., El-Hammuri N., Aljesrawi A., Alamaadany F., Eljareh M., Al Gasi A.E.J., Alsaeiti S., Alkhafeefi A.S., Suliaman T., Alanasri A.H.A., Haroun A.B.A., Haron A., Kilani A.I., Ahmed M., Alawami M., Alawami A., Albashri 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Bhat, S., van der Have, J., Anderson, C., Bissett, I., Windsor, J., Elliott, B M, Scowcroft, H., Mclauchlan, J., Ritchie, D., Jeffery, F., Connor, S., Xu, W., Mashlan, H., Thirayan, V., Ly, J., Mcguinness, M J, Ferguson, L., Watt, I., Harmston, C., Akinmade, A., Enoch, E., Kayode-Nissi, V., Ogundele, I., Ayoade, B A, Adekoya, A., Nwokoro, C., Opadeyi, A., Yusuf, A., Ojajuni, A., Adepoju, O., Muhammad Dauda, Maigatari, Keffi Mubarak, Musa, Lawal, Khalid, Muhammad, Daniyan, Salonga, D., Sael, N A, Rey, C M, Pestano, M., Tan, D., Bangayan, N R, Sy, D K, Ang, D., Bernardo, E., Chua, J P, Alharthi, M., Bukhari, W., Bakier Mohammed, K., Al Athath, S., Ghunaim, M., Saiedi, H., Sultan, N., Farsi, A., Basendowah, M., Malibary, N., Jaloun, H., Altalhi, Db, Organjee, A., Moamena, M., Al Zaidi, T M, Alyami, M., Alqannas, M., Al-Urfan, M., Elawad, A., Alawadhi, A., Alalawi, Y., Alqarni, A., Alqahtani, B., Alayed, A., Alsobaie, K., Adi, H., Elhaj, M., Dehlawi, A., Behairy, G., Khaled, I., Kmezic, S., Radenkovic, D., Aleksic, L., Markovic, V., Pejovic, I., Antic, A., Kalkan, M., Vujanovic Gadjanski, O., Dusan, S., Marčetić, B., Thiruchelvam, N., Chiow, Akh, Lee, L S, Mun, Dyc, Tan, E K, Koh, Y X, Loh, W L, Wang, Z., Chan, C Y, Ibrahim, M., Hamid, Hks, Idres, R., Idris, M., Mohammed, O., Ayran, S., Sinan, A H, Ozben, V., Aytac, E., Aliyeva, Z., Mutlu, A U, Bilgin, I A, Karahasanoglu, T., Hamzaoglu, I., Bozkirli, B., Uprak, T K, Kotan, T., Coskun, M., Kara, Y., Somuncu, E., Kocatas, A., Bozkurt, M A, Demirli Atici, S., Kaya, T., Sert, I., Emiroglu, M., Jaffar, M., Younis, M U, Aziz, T., Ikram, F., Sandal, M., Al Madhloum Al Suwaidi, F., Alshaikh, M O, Saber, A., Khammas, A., Nessa, A., Jardine, R., Nicol, L., Clark, C., Mcgee, A., Alkari, B., Feretis, M., Antakia, R., Georgiades, F., Moneim, J., O'Neill, R., Balakrishnan, A., Lunevicius, R., Sud, A., Moutsos, I., Gomez, D., Shahid, S., Majeed, T., Ibrahim, Wkg, Kadum, K., Melia, R., Magee, C., Chicken, D W, Kumar, S., Alshibshoubi, M., van Laarhoven, S., Dewi, F., Williams, J., Byrne, B., Wilkerson, P., Tang, C B, Farhangmehr, N., Jonas, A., Charavanamuttu, V., Almeida, K., Efthimiou, E., Boardley, J., White, A., Butt, M A, Menzies, D., Gundkalli, Z., Hassanzadeh-Baboli, D., Jones, O., Mistry, P., Saha, S., Gerrard, A., Evans, J., Rajeev, S., Ali, W., Ross, E., Gilliam, A., Hitchins, C., Emslie, K., Spellar, K., Sked, H., Briggs, C., Brown, L., A Hemadasa, N., Apollos, J R, Belgaumkar, A., Tawfik, A., Brewin, L., Oyewole, B., Wadhawan, H., Massie, E., Rutherford, D., Mcgivern, K., Mcelroy, L., De'Ath, H D, Tobbal, M., Nagendram, S., Patel, P., Handa, S., Houghton, G., Sundaralingam, S S, Parker, J., Morgan, R., Gala, T., Ibrahim, S., Mithany, R., Abdelkarim, M., Holroyd, D., Thomas, R., Mclennan, E., Boardley, R., Jamieson, N B, Ebied, H., Gossage, J., Davies, A., Wheatstone, S., Jawad, Z., Jiao, L., Rajagopal, P., Sodergren, M., Lami, M., Wiberg, A., Bond-Smith, G., Gemmill, E., Lenzi, E., Sapre, D., Herrod, P., Boyd-Carson, H., Garcea, G., Issa, E., Jackson, A., Fashina, T., Pan, H., Farquharson, B., Shafiq, H., Emanuel, O., Mahdi, S., Jeyarajah, S., Finch, L., Whiting, G., Pigott, L., Martin, J., Siriwardena, A., Beatson, K., Abawi, L., Lam, W., Rea, W., Andrews, B., Al-Sarireh, B., Soliman, F., Burridge, J., Jenvey, C., Hammoda, M., Hollyman, M., Merker, L., Richards, J., Sukumaran, V., Rogers, S., Payne, C., Bibi, S., Raza, K., Ul Ain, N., Dronamraju, S., Patil, S., Nachimuthu, S., Ravindran, S., Patel, S., Ivanov, B., Patel, M., Ejtehadi, F., Jebamani, J., Akhter Rahman, M M, Woodun, H., De Prendergast, A., Afzal, A., Bota, E., Abdul, S R, Karmarkar, R., Crockett, E., Evans, L., Appleton, B., Griffiths, E., Dada, O., Kulkarni, R., Albirnawi, H., Gravestock, P., Vincenti, C., Taribagil, S., Dent, B., Tse, C., Clayton, B., Burdekin, E., Bannister, L., Alam, I., Gray, J., Mactier, M., Pollock, A., Gough, V., Kanchustambam, S R, Ridgway, M., Arujunan, K., Gopalswamy, S., Monteiro De Barros, J., Lyons, T., Griffith, D., Awan, A K, Latif, J., Bandlamudi, N., Bhatti, I., Raptis, D A, Machairas, N., Pissanou, T., Mestre-Costa, J., Hidalgo Salinas, C., Pollok, J M, Al-Ardah, M., Watson-Jones, E., Rontree-Carey, T., Boyce, T., Hawkin, P., Elmaradny, A., Ross, K., Adu-Peprah, E., Pinto, K., Dunne, D., Mccready, R., Nita, G., Szatmary, P., Tay, V L, Rajput, K., Rajendran, I., Chaudhury, M., Zambas, G., Swaminathan, C., Atif, Qaa, Barrow, T., Williams, O., Malik, A., Conroy, S., Lindley, S., Gilmore, K., Boden, E., Richards, S K, Hraishawi, I., Polak, P., Mclaughlin, D., Deeny, D., Shuttleworth, R., Harris, A., Peilober-Richardson, A., Morris, G C, Sara, X., Almourad, H., Ang, Y., Smyth, R., Ding, D., Foster, J., Bond, A., Kumar, Y., Ahmad, A., Radoi, D., Alkaili-Alyamani, A., Balakrishnan, S., Satchidanand, R Y, Danwaththa Liyanage, A S, Blake, I., Ransome, M., Weerasinghe, C., Kenington, C., Mayo, K., Mohammed, M., Cockbain, A J, Peckham-Cooper, A., Mccauley, G., Gordon, C., Smith, A., Hawkins, W., Chakravartty, S., Baillie, C., Kenny, R., Kumar, A., Koimtzis, G., Bellamy, E., Menon, A., Kanakala, A., Nevins, E J, Madhavan, A., Thulasiraman, S., France, K., O'Connor, A., Idama, D., Raslan, C., Sridhar, S., Parveen, M., Mubashar, T., Jarvis, S., Cakmak, I., Wright, C., Andrews, S., Abdelsaid K Abdul Aal, Y., Jayasankar, B., Morilla, J., Shehata, M., Subba, N., Tewari, N., El-Sayed, C., Somaie, D., Beheiry, N., Douka, E., Arumugam, S., Wijetunga, I., Leivers, E., Ibrahim, B., Khan, K., Wheat, J., Christopher, J., Barnett, R., Elberm, H., Booker, J., Ashai, S., Berry, D., Luhmann, A., Sgro, A., Rashid, M M, Galea, M., Jeyakumar, J., Marriott, P., Zafar, S., Baker, A., Yershov, D., Galanopoulos, G., Jordan, R., Peinado Garcia, C., Anyaugo, N., Bath, M F, Omatseye, J., Roberts, L., Argyriou, E O, Machesney, M., Parmar, C., Clark, S., Khalil, H., Unsworth, S., Mlotshwa, M., Ayoub, N., Aboelkhair, A., Iosif, E., Mohamed, N., Reynolds, E., Mackender, E., Robinson, D., Mufti, W., Fischkoff, K., Coleman, N., Anantha Sathyanarayana, S., Deutsch, G., Giangola, M., Lin, D., Weiss, M., Chung, C., Nguyen, A., Mueller, J., Dabit, M., Gordon, J., McGuire, E., Rashid, O., Georgi, E., Gallo, M., Kunstman, J W, Peters, N V, O'Connor, R., Bhattacharya, B., Onkendi, E., Santos, A P, Richmond, R., Warren, M., Zhang, K., Broderick, R., Clary, B., Horgan, S., Doucet, J., Liepert, A., Harmon, L., McCall, C., Sham, J G, Williams, E., Labadie, K P, Clark, N M, Dickerson, L K, Hammill, C W, Williams, G., Kushner, B., Cos, H., Zarate Rodriguez, J., Bailey, K., Al-Raimi, Imn, Al-Zazay, K., Ahmed Mohammed Al-Mahdi, S., Mohammed Aldowbli, S., Al-Shehari, M., Shream, S., Al-Ameri, S., Aeed, M., Aldawbali, M., Alsayadi, R., and Alsayadi, M.
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Pandemic ,SARS-CoV-2 ,acute cholecystitis ,COVID-19 ,management ,Cholecystitis, Acute ,acute ,General Medicine ,pandemics ,cholecystectomy ,humans ,cholecystitis ,Cholecystectomy ,Humans ,Pandemics ,Settore MED/18 - Chirurgia Generale ,Human - Abstract
Background This study provides a global overview of the management of patients with acute cholecystitis during the initial phase of the COVID-19 pandemic. Methods CHOLECOVID is an international, multicentre, observational comparative study of patients admitted to hospital with acute cholecystitis during the COVID-19 pandemic. Data on management were collected for a 2-month study interval coincident with the WHO declaration of the SARS-CoV-2 pandemic and compared with an equivalent pre-pandemic time interval. Mediation analysis examined the influence of SARS-COV-2 infection on 30-day mortality. Results This study collected data on 9783 patients with acute cholecystitis admitted to 247 hospitals across the world. The pandemic was associated with reduced availability of surgical workforce and operating facilities globally, a significant shift to worse severity of disease, and increased use of conservative management. There was a reduction (both absolute and proportionate) in the number of patients undergoing cholecystectomy from 3095 patients (56.2 per cent) pre-pandemic to 1998 patients (46.2 per cent) during the pandemic but there was no difference in 30-day all-cause mortality after cholecystectomy comparing the pre-pandemic interval with the pandemic (13 patients (0.4 per cent) pre-pandemic to 13 patients (0.6 per cent) pandemic; P = 0.355). In mediation analysis, an admission with acute cholecystitis during the pandemic was associated with a non-significant increased risk of death (OR 1.29, 95 per cent c.i. 0.93 to 1.79, P = 0.121). Conclusion CHOLECOVID provides a unique overview of the treatment of patients with cholecystitis across the globe during the first months of the SARS-CoV-2 pandemic. The study highlights the need for system resilience in retention of elective surgical activity. Cholecystectomy was associated with a low risk of mortality and deferral of treatment results in an increase in avoidable morbidity that represents the non-COVID cost of this pandemic.
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- 2022
17. The Neural Effects of Extended Practice and the Benefits of a Nap
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Ricci, S., primary, Nelson, A. B., additional, Tatti, E., additional, Panday, P., additional, Lin, J., additional, Thomson, B. O., additional, Chen, H., additional, Tononi, G., additional, Cirelli, C., additional, and Ghilardi, M. F., additional
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- 2018
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18. Advantages of an API Source for Analysis by Liquid Chromatography/Mass Spectrometry
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Thomson, B. A., primary, Ngo, A., additional, and Shushan, B. I., additional
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- 2018
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19. New Observations of Recently Active Wrinkle Ridges in the Lunar Mare: Implications for the Timing and Origin of Lunar Tectonics
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Nypaver, C. A., primary and Thomson, B. J., additional
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- 2022
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20. Smoking and cause-specific mortality in large prospective studies from Cuba, Mexico, and the United States
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Thomson, B, Emberson, J, Lewington, S, Lacey, B, and Peto, R
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Epidemiology - Abstract
Background: Tobacco smoking caused an estimated 100 million deaths in the 20th century, and unless widespread cessation and prevention occur, it could cause one billion deaths in the 21st century. An estimated 50 million smokers live in Latin America, but there is little direct evidence of the effects of smoking in Latin American populations. Methods: Information from three large, prospective studies of Latin American populations was used to determine the relevance of smoking and smoking cessation to mortality. In 1996-2002, 146 556 Cuban adults aged ≥30 years were recruited into the Cuba Prospective Study, of whom 8691 died at ages 30-69 during follow-up. In 1998-2004, 159 755 Mexican adults aged ≥35 years were recruited into the Mexico City Prospective Study, of whom 19 091 died at ages 35-89 during follow-up (10 773 without major chronic disease at recruitment, and 8318 with major chronic disease). Finally, in 1997-2014, 446 531 adults aged ≥30 years were recruited into the US National Health Interview Survey, of whom 48 440 died at ages 30-89 during follow-up (3242 Mexican Americans, 2177 other Hispanics, 34 482 non-Hispanic Whites, 6978 non-Hispanic Blacks, and 1561 participants of other race/ethnicity). In each prospective study, Cox regression (adjusting for age-at-risk, sex, education, area, and alcohol consumption) was used to relate smoking habits at recruitment to mortality rate ratios (RRs). Resurveys of Cuban and Mexican participants informed ‘usual’ smoking behaviours. Results: In the Cuba Prospective Study, half of men and one-quarter of women were smokers at recruitment. One-third of current cigarette smokers reported having started smoking regularly in childhood (age Conclusions: In Cubans, Mexicans, and Mexican Americans, the excess mortality risk associated with smoking was substantial, but was lower than the risk associated with smoking among Western populations. This may be due to a combination of intermittent smoking patterns in each of these populations, lower levels of consumption among Mexicans and Mexican Americans, and variability in products smoked over time. This thesis provides the first reliable, direct evidence of the relationship between smoking and mortality in Cuba and Mexico, which led to estimates of smoking-attributable mortality similar to those from the Global Burden of Disease (GBD) Study. Therefore, the GBD Study may provide the best available estimates of smoking-attributable mortality in other Latin American populations in which there is not yet direct evidence.
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- 2022
21. Phylogenetically and functionally diverse microorganisms reside under the Ross Ice Shelf
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Martínez-Pérez, C., Greening, C., Bay, S.K., Lappan, R.J., Zhao, Z., De Corte, D., Hulbe, C., Ohneiser, C., Stevens, C., Thomson, B., Stepanauskas, R., González, J.M., Logares, R., Herndl, G.J., Herndl, G., Morales, S.E., Baltar, F., Martínez-Pérez, C., Greening, C., Bay, S.K., Lappan, R.J., Zhao, Z., De Corte, D., Hulbe, C., Ohneiser, C., Stevens, C., Thomson, B., Stepanauskas, R., González, J.M., Logares, R., Herndl, G.J., Herndl, G., Morales, S.E., and Baltar, F.
- Abstract
Throughout coastal Antarctica, ice shelves separate oceanic waters from sunlight by hundreds of meters of ice. Historical studies have detected activity of nitrifying microorganisms in oceanic cavities below permanent ice shelves. However, little is known about the microbial composition and pathways that mediate these activities. In this study, we profiled the microbial communities beneath the Ross Ice Shelf using a multi-omics approach. Overall, beneath-shelf microorganisms are of comparable abundance and diversity, though distinct composition, relative to those in the open meso- and bathypelagic ocean. Production of new organic carbon is likely driven by aerobic lithoautotrophic archaea and bacteria that can use ammonium, nitrite, and sulfur compounds as electron donors. Also enriched were aerobic organoheterotrophic bacteria capable of degrading complex organic carbon substrates, likely derived from in situ fixed carbon and potentially refractory organic matter laterally advected by the below-shelf waters. Altogether, these findings uncover a taxonomically distinct microbial community potentially adapted to a highly oligotrophic marine environment and suggest that ocean cavity waters are primarily chemosynthetically-driven systems.
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- 2022
22. Real-world staging computed tomography scanning technique and important reporting discrepancies in pancreatic ductal adenocarcinoma
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Grogan, A, Loveday, B, Michael, M, Wong, H-L, Gibbs, P, Thomson, B, Lee, B, Ko, HS, Grogan, A, Loveday, B, Michael, M, Wong, H-L, Gibbs, P, Thomson, B, Lee, B, and Ko, HS
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BACKGROUND: Computed tomography (CT) is the first-line staging imaging modality for pancreatic ductal adenocarcinoma (PDAC) which determines resectability and treatment pathways. METHODS: Between January 2016 and December 2019, prospectively collated data from two Australian cancer centres was extracted from the PURPLE Pancreatic Cancer registry. Real-world staging CTs and corresponding reports were blindly reviewed by a sub-specialist radiologist and compared to initial reports. RESULTS: Of 131 patients assessed, 117 (89.3%) presented with symptoms, 74 (56.5%) CTs included slices ≤3 mm thickness and CT pancreas protocol was applied in 69 (52.7%) patients. Initial reports lacked synoptic reporting in 131 (100%), tumour identification in 2 (1.6%) and tumour measurement in 13 (9.9%) cases. Tumour-vascular relationship reporting was missing in 69-109 (52.7-83.2%) for regarding the key arterial and venous structures that is required to assess resectability. Initial reports had no comment on venous thrombus or venous collaterals in 80 (61.1%) and 109 (83.2%) and lacked locoregional lymphadenopathy interpretation in 13 (9.9%) cases. Complete initial staging report was present in 72 (55.0%) patients. Sub-specialist radiological review resulted in down-staging in 16 (22.2%) and up-staging in 1 (1.4%) patient. Staging discrepancies were mainly regarding metastatic disease (12, 70.6%) and tumour-vascular relationship (5, 29.4%). CONCLUSION: Real-world staging imaging in PDAC patients show low proportion of dedicated CT pancreas protocol, high proportion of incomplete staging reports and no synoptic reporting. The most common discrepancy between initial and sub-specialist reporting was regarding metastases and tumour-vascular relationship assessment resulting in sub-specialist down-staging in almost every fifth case.
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- 2022
23. Treatment and outcomes of unresectable and metastatic pancreatic cancer treated in public and private Australian hospitals
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To, YH, Shapiro, J, Wong, R, Thomson, B, Nagrial, A, Mendis, S, Gibbs, P, Lee, B, To, YH, Shapiro, J, Wong, R, Thomson, B, Nagrial, A, Mendis, S, Gibbs, P, and Lee, B
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BACKGROUND: Prior studies have reported for several cancer types that treatment in the private sector is associated with improved survival outcomes. Data for patients with locally advanced unresectable and metastatic pancreatic ductal adenocarcinoma (PDAC) have not previously been reported. METHODS: Analysis of patients from January 2016 to June 2020 registered to a multicentre prospective cancer database. Baseline demographic and clinicopathologic characteristics were compared. The Kaplan-Meier method was used to compare overall survival (OS). Multivariate Cox and logistic regression analyses were used to determine predictors of mortality and first-line chemotherapy treatment, respectively. RESULTS: Of 822 patients, 22.5% received private care. Private patients were older (median 71.5 vs. 68.9 years, p ≤ .05), had better performance status (ECOG 0 to 1: 82.2 vs. 73.5%, p = .05) and more likely to reside in an area with high socioeconomic advantage (67.0 vs. 19.6%, p ≤ .01). Private patients were more likely to receive first-line chemotherapy (69.7 vs. 54.2%, p ≤ .01) with logistic regression demonstrating private care (OR: 1.87, 95% CI: 1.20 to 2.97) as an independent predictor of receiving chemotherapy. Private patients had prolonged survival (median OS: 9.2 vs. 6.9 months, HR 1.2, p = .05). Receiving first-line chemotherapy was an independent predictor of mortality, but private care was not. CONCLUSIONS: Care in the private system is associated with improved OS, with higher uptake of first-line chemotherapy appearing to be the main contributor. Given the discrepancy, further studies are needed to determine what factors are driving this difference.
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- 2022
24. An algorithm for the management of traumatic abdominal wall hernia based on a 9-year review.
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Wong, J, Peng, C, Shakerian, R, Knowles, B, Thomson, B, Read, DJ, Wong, J, Peng, C, Shakerian, R, Knowles, B, Thomson, B, and Read, DJ
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BACKGROUND: Traumatic abdominal wall hernia (TAWH) is a rare consequence of blunt abdominal trauma, usually in the setting of multitrauma, with little consensus or guidelines for management. We present a case series of patients with traumatic herniae over a 9-year period and a suggested management algorithm. METHOD: Retrospective review of all patients with TAWH from 1st January 2011 to 31st December 2019 at a Level 1 adult Major Trauma Centre. Clinical presentation, surgical intervention and complications and recurrence were analysed. RESULTS: Forty-seven patients were found to have TAWH, 0.5% of all major trauma admissions. Thirty (63.8%) were repaired, 12 acutely, 11 semi-acute and 7 delayed. All but 1 (fall>3 m) were transport associated, with a median Injury Severity Score (ISS) of 29. Follow-up data for operative cases were available for all but one (97%). Seven (23.3%) cases had a recurrence, more common in the acute repair group (33.3%) compared to semi-acute (18.2%), and elective group (14.3%). CONCLUSION: TAWH is a rare but potentially serious consequence of blunt abdominal trauma. This series has favoured earlier repair for anterior TAWH, or all those undergoing a laparotomy for other reasons, and elective repair for lumbar or lateral TAWH that do not require a laparotomy for other conditions. We present our preferred algorithm for management, accepting that there are many available strategies in this heterogeneous group of injuries. Loss of follow up and recurrence are a concern, and clinicians are encouraged to develop processes to ensure that TAWH are not a 'forgotten hernia'.
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- 2022
25. PO-1293 A dosimetric evaluation of 4D-CT vs 3D-CT in mid and lower third upper GI Patients
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Stewart-Thomson, B., primary
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- 2022
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26. Evolution of Circular Polarization Ratio (CPR) Profiles of Kilometer-scale Craters on the Lunar Maria
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King, I. R, Fassett, C. I, Thomson, B. J, Minton, D. A, and Watters, W. A
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Lunar And Planetary Science And Exploration - Abstract
When sufficiently large impact craters form on the Moon, rocks and unweathered materials are excavated from beneath the regolith and deposited into their blocky ejecta. This enhances the rockiness and roughness of the proximal ejecta surrounding fresh impact craters. The interior of fresh craters are typically also rough, due to blocks, breccia, and impact melt. Thus, both the interior and proximal ejecta of fresh craters are usually radar bright and have high circular polarization ratios (CPR). Beyond the proximal ejecta, radar-dark halos are observed around some fresh craters, suggesting that distal ejecta is finer-grained than background regolith. The radar signatures of craters fade with time as the regolith grows.
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- 2017
27. Obtaining and Using Planetary Spatial Data into the Future: The Role of the Mapping and Planetary Spatial Infrastructure Team (MAPSIT)
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Radebaugh, J, Thomson, B. J, Archinal, B, Hagerty, J, Gaddis, L, Lawrence, S. J, and Sutton, S
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Documentation And Information Science ,Administration And Management - Abstract
Planetary spatial data, which include any remote sensing data or derived products with sufficient positional information such that they can be projected onto a planetary body, continue to rapidly increase in volume and complexity. These data are the hard-earned fruits of decades of planetary exploration, and are the end result of mission planning and execution. Maintaining these data using accessible formats and standards for all scientists has been necessary for the success of past, present, and future planetary missions. The Mapping and Planetary Spatial Infrastructure Team (MAPSIT) is a group of planetary community members tasked by NASA Headquarters to work with the planetary science community to identify and prioritize their planetary spatial data needs to help determine the best pathways for new data acquisition, usable product derivation, and tools/capability development that supports NASA's planetary science missions.
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- 2017
28. Surgical Management of Aortic Root Thrombus in Acute Severe Ischaemic Cardiomyopathy Patient Supported With Continuous-Flow Left Ventricular Assist Device.
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Shahwar, D. and Thomson, B.
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HEART assist devices , *THROMBOSIS , *AORTA , *CARDIOMYOPATHIES - Published
- 2024
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29. Type 2 Diabetes does not worsen prognosis in hepatocellular carcinoma
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Howell, J., Yiu, M., Gibson, R., Thomson, B., Stella, D., Gorelik, A., Prichard, P.J., and Nicoll, A.J.
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- 2011
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30. A Closer Look at Water-Related Geologic Activity on Mars
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McEwen, A. S., Hansen, C. J., Delamere, W. A., Eliason, E. M., Herkenhoff, K. E., Keszthelyi, L., Gulick, V. C., Kirk, R. L., Mellon, M. T., Grant, J. A., Thomas, N., Weitz, C. M., Squyres, S. W., Bridges, N. T., Murchie, S. L., Seelos, F., Seelos, K., Okubo, C. H., Milazzo, M. P., Tornabene, L. L., Jaeger, W. L., Byrne, S., Russell, P. S., Griffes, J. L., Martínez-Alonso, S., Davatzes, A., Chuang, F. C., Thomson, B. J., Fishbaugh, K. E., Dundas, C. M., Kolb, K. J., Banks, M. E., and Wray, J. J.
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- 2007
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31. Association of smoking initiation and cessation across the life course and cancer mortality
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Thomson, B, Emberson, J, Lacey, B, Lewington, S, Peto, R, and Islami, F
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- 2021
32. Hydrodynamic evaluation of aortic cardiopulmonary bypass cannulae using particle image velocimetry
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Bolle, E, McDonald, CI, Lang, H F, Ribolzi, C, Thomson, B, Tansley, G D, Fraser, J F, and Gregory, S D
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- 2016
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33. Bistatic Radar Observations of the Moon Using Mini-RF on LRO and the Arecibo Observatory
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Patterson, G. W, Stickle, A. M, Turner, F. S, Jensen, J. R, Bussey, D. B. J, Spudis, P, Espiritu, R. C, Schulze, R. C, Yocky, D. A, Wahl, D. E, Zimmerman, M, Cahill, J. T. S, Nolan, M, Carter, L, Neish, C. D, Raney, R. K, Thomson, B. J, Kirk, R, Thompson, T.W, Tise, B. L, Erteza, I. A, and Jakowatz, C. V
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Lunar And Planetary Science And Exploration ,Geosciences (General) - Abstract
The Miniature Radio Frequency (Mini-RF) instrument aboard NASA's Lunar Reconnaissance Orbiter (LRO) is a hybrid dual-polarized synthetic aperture radar (SAR) that operated in concert with the Arecibo Observatory to collect bistatic radar data of the lunar nearside from 2012 to 2015. The purpose of this bistatic campaign was to characterize the radar scattering properties of the surface and near-surface, as a function of bistatic angle, for a variety of lunar terrains and search for a coherent backscatter opposition effect indicative of the presence of water ice. A variety of lunar terrain types were sampled over a range of incidence and bistatic angles; including mare, highland, pyroclastic, crater ejecta, and crater floor materials. Responses consistent with an opposition effect were observed for the ejecta of several Copernican-aged craters and the floor of the south-polar crater Cabeus. The responses of ejecta material varied by crater in a manner that suggests a relationship with crater age. The response for Cabeus was observed within the portion of its floor that is not in permanent shadow. The character of the response differs from that of crater ejecta and appears unique with respect to all other lunar terrains observed. Analysis of data for this region suggests that the unique nature of the response may indicate the presence of near-surface deposits of water ice.
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- 2016
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34. Heterocyclic amine levels in cooked meat and the implication for New Zealanders
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Thomson, B
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- 1999
35. PTH-314 Curative management for stage IV rectal cancer – has the potential improved?
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Rajendran, N, Yap, K, Kaneko, Y, Thomson, B, Ngan, S, Michael, M, Lynch, C, Warrier, SK, and Heriot, AG
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- 2015
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36. PTH-313 Stage iv rectal cancer survival outcomes – a 25 year experience
- Author
-
Rajendran, N, Yap, K, Kaneko, Y, Thomson, B, Ngan, S, Michael, M, Lynch, C, Warrier, SK, and Heriot, AG
- Published
- 2015
- Full Text
- View/download PDF
37. Path Derivatives: A Unified View of Certain Generalized Derivatives
- Author
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Bruckner, A. M., O'Malley, R. J., and Thomson, B. S.
- Published
- 1984
- Full Text
- View/download PDF
38. New Synthesis Routes for Energetic Materials Using Dinitrogen Pentoxide [and Discussion]
- Author
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Millar, R. W., Colclough, M. E., Golding, P., Honey, P. J., Paul, N. C., Sanderson, A. J., Stewart, M. J., Volk, F., and Thomson, B. J.
- Published
- 1992
39. Soil Mediated Effects of Phosphorus Supply on the Formation of Mycorrhizas by Scutellispora calospora (Nicol. & Gerd.) Walker & Sanders on Subterranean Clover
- Author
-
Thomson, B. D., Robson, A. D., and Abbott, L. K.
- Published
- 1991
40. Mycorrhizas Formed by Gigaspora calospora and Glomus fasciculatum on Subterranean Clover in Relation to Soluble Carbohydrate Concentrations in Roots
- Author
-
Thomson, B. D., Robson, A. D., and Abbott, L. K.
- Published
- 1990
41. Kinetics of Phosphorus Uptake by the Germ-Tubes of the Vesicular- Arbuscular Mycorrhizal Fungus, Gigaspor magarita
- Author
-
Thomson, B. D., Clarkson, D. T., and Brain, P.
- Published
- 1990
42. The Effectiveness of Ectomycorrhizal Fungi in Increasing the Growth of Eucalyptus globulus Labill. in Relation to Root Colonization and Hyphal Development in Soil
- Author
-
Thomson, B. D., Grove, T. S., and Malajczuk, N.
- Published
- 1994
43. Effects of Phosphorus on the Formation of Mycorrhizas by Gigaspora calospora and Glomus fasciculatum in Relation to Root Carbohydrates
- Author
-
Thomson, B. D., Robson, A. D., and Abbott, L. K.
- Published
- 1986
44. Systematic Increase in Pollen Carryover and Its Consequences for Geitonogamy in Plant Populations
- Author
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Morris, W. F., Price, M. V., Waser, N. M., Thomson, J. D., Thomson, B., and Stratton, D. A.
- Published
- 1994
- Full Text
- View/download PDF
45. Applications of a Versatile Technique for Trace Analysis: Atmospheric Pressure Negative Chemical Ionization
- Author
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Thomson, B. A., Davidson, W. R., and Lovett, A. M.
- Published
- 1980
- Full Text
- View/download PDF
46. Monotonicity Theorems
- Author
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Thomson, B. S.
- Published
- 1981
- Full Text
- View/download PDF
47. Comparative Growth and Atrazine Response of Resistant and Susceptible Populations of Amaranthus From Southern Ontario
- Author
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Weaver, S. E., Warwick, S. I., and Thomson, B. K.
- Published
- 1982
- Full Text
- View/download PDF
48. Preoperative immunonutrition and its effect on postoperative outcomes in well-nourished and malnourished gastrointestinal surgery patients: a randomised controlled trial
- Author
-
Barker, L A, Gray, C, Wilson, L, Thomson, B N J, Shedda, S, and Crowe, T C
- Published
- 2013
- Full Text
- View/download PDF
49. Construction of Measures and Integrals
- Author
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Thomson, B. S.
- Published
- 1971
- Full Text
- View/download PDF
50. Deletion of Cdh16 Ksp-cadherin leads to a developmental delay in the ability to maximally concentrate urine in mouse
- Author
-
Thomson, R. B., primary, Dynia, D. W., additional, Burlein, S., additional, Thomson, B. R., additional, Booth, C. J., additional, Knauf, F., additional, Wang, T., additional, and Aronson, P. S., additional
- Published
- 2021
- Full Text
- View/download PDF
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