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This article is intended to ‘brush up’ on the literature updates for management of head and neck surgeries, particularly mandibulectomy and maxillectomy. Few new techniques have been described on the last decade in dental and oral oncological surgery. A tendency of developing more aggressive surgical strategies to treat complex oral tumors is evident by the recent veterinary literature and the emerging novel techniques for bone regeneration of maxillofacial defects. Additionally, this article also focuses on the basic oral surgical oncology principles, an important part of any maxillofacial surgery.