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Low back pain (LBP) is a leading cause of disability globally. Following the onset of LBP and subsequent treatment, adequate patient education is crucial for improving functionality and long-term outcomes. Despite advancements in patient education strategies, significant gaps persist in delivering personalized, evidence-based information to patients with LBP. Recent advancements in large language models (LLMs) and generative artificial intelligence (GenAI) have demonstrated the potential to enhance patient education. However, their application and efficacy in delivering educational content to patients with LBP remain underexplored and warrant further investigation. In this study, we introduce a novel approach utilizing LLMs with Retrieval-Augmented Generation (RAG) and few-shot learning to generate tailored educational materials for patients with LBP. Physical therapists manually evaluated our model responses for redundancy, accuracy, and completeness using a Likert scale. In addition, the readability of the generated education materials is assessed using the Flesch Reading Ease score. The findings demonstrate that RAG-based LLMs outperform traditional LLMs, providing more accurate, complete, and readable patient education materials with less redundancy. Having said that, our analysis reveals that the generated materials are not yet ready for use in clinical practice. This study underscores the potential of AI-driven models utilizing RAG to improve patient education for LBP; however, significant challenges remain in ensuring the clinical relevance and granularity of content generated by these models.

The Large Binocular Telescope, with its expansive collecting area, angular resolving power, and advanced optical design, provides a robust platform for development and operation of advanced instrumentation for astronomical research. The LBT currently hosts a mature suite of instruments for spectroscopy and imaging at optical through mid-infrared wavelengths, supported by sophisticated adaptive optics systems. This contribution summarizes the current state of instrumentation, including upgrades to existing instruments and commissioning of second generation instruments now in progress. The LBT is soliciting proposals for next generation instrument concepts, with participation open to consortium members and others interested in participation in the Observatory., Comment: 6 pages, Proc. SPIE 13096-4, Ground-based and Airborne Instrumentation for Astronomy X, Yokohama 2024

Planetary rovers can use onboard data analysis to adapt their measurement plan on the fly, improving the science value of data collected between commands from Earth. This paper describes the implementation of an adaptive sampling algorithm used by PIXL, the X-ray fluorescence spectrometer of the Mars 2020 Perseverance rover. PIXL is deployed using the rover arm to measure X-ray spectra of rocks with a scan density of several thousand points over an area of typically 5 x 7 mm. The adaptive sampling algorithm is programmed to recognize points of interest and to increase the signal-to-noise ratio at those locations by performing longer integrations. Two approaches are used to formulate the sampling rules based on past quantification data: 1) Expressions that isolate particular regions within a ternary compositional diagram, and 2) Machine learning rules that threshold for a high weight percent of particular compounds. The design of the rulesets are outlined and the performance of the algorithm is quantified using measurements from the surface of Mars. To our knowledge, PIXL's adaptive sampling represents the first autonomous decision-making based on real-time compositional analysis by a spacecraft on the surface of another planet., Comment: 24 pages including 11 figures and 7 tables. Submitted for publication to the journal Icarus

At speeds above 300 km/h, aerodynamic noise becomes a significant source of railway noise. In a high-speed train, the bogie area is one of the most important aerodynamic noise sources. To predict aerodynamic noise, semi-empirical component-based models are attractive as they allow fast and cheap calculations compared with numerical methods. Such component-based models have been previously applied successfully to predict the aerodynamic noise from train pantographs which consist of various cylinders. In this work, the feasibility is evaluated of applying them to the aerodynamic noise from bogies, which consist of various bluff bodies. To this end, noise measurements were carried out in an anechoic wind tunnel for different flow speeds using simple shapes representing various idealised components of a bogie. These results have been used to adjust the empirical constants of the component-based prediction model to enable its application to the bogie case. In addition, the noise from a 1:10 scale simplified bogie mock-up was measured and used for comparison with the prediction model. The results show good agreement between measurements and predictions for the bogie alone. When the bogie is located between two ramps approximating a simplified bogie cavity the noise is underpredicted at low frequencies. This is attributed to the noise from the cavity which is not included in the model.

The joint retrieval of surface reflectances and atmospheric parameters in VSWIR imaging spectroscopy is a computationally challenging high-dimensional problem. Using NASA's Surface Biology and Geology mission as the motivational context, the uncertainty associated with the retrievals is crucial for further application of the retrieved results for environmental applications. Although Markov chain Monte Carlo (MCMC) is a Bayesian method ideal for uncertainty quantification, the full-dimensional implementation of MCMC for the retrieval is computationally intractable. In this work, we developed a block Metropolis MCMC algorithm for the high-dimensional VSWIR surface reflectance retrieval that leverages the structure of the forward radiative transfer model to enable tractable fully Bayesian computation. We use the posterior distribution from this MCMC algorithm to assess the limitations of optimal estimation, the state-of-the-art Bayesian algorithm in operational retrievals which is more computationally efficient but uses a Gaussian approximation to characterize the posterior. Analyzing the differences in the posterior computed by each method, the MCMC algorithm was shown to give more physically sensible results and reveals the non-Gaussian structure of the posterior, specifically in the atmospheric aerosol optical depth parameter and the low-wavelength surface reflectances.

We present 294 pulsars found in GeV data from the Large Area Telescope (LAT) on the Fermi Gamma-ray Space Telescope. Another 33 millisecond pulsars (MSPs) discovered in deep radio searches of LAT sources will likely reveal pulsations once phase-connected rotation ephemerides are achieved. A further dozen optical and/or X-ray binary systems co-located with LAT sources also likely harbor gamma-ray MSPs. This catalog thus reports roughly 340 gamma-ray pulsars and candidates, 10% of all known pulsars, compared to $\leq 11$ known before Fermi. Half of the gamma-ray pulsars are young. Of these, the half that are undetected in radio have a broader Galactic latitude distribution than the young radio-loud pulsars. The others are MSPs, with 6 undetected in radio. Overall, >235 are bright enough above 50 MeV to fit the pulse profile, the energy spectrum, or both. For the common two-peaked profiles, the gamma-ray peak closest to the magnetic pole crossing generally has a softer spectrum. The spectral energy distributions tend to narrow as the spindown power $\dot E$ decreases to its observed minimum near $10^{33}$ erg s$^{-1}$, approaching the shape for synchrotron radiation from monoenergetic electrons. We calculate gamma-ray luminosities when distances are available. Our all-sky gamma-ray sensitivity map is useful for population syntheses. The electronic catalog version provides gamma-ray pulsar ephemerides, properties and fit results to guide and be compared with modeling results., Comment: 142 pages. Accepted by the Astrophysical Journal Supplement