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295 results on '"Thirion, X."'

5. Standardization and quality control studies of ‘real-time’ quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia – A Europe Against Cancer Program

Author

Gabert, J, Beillard, E, van der Velden, V H J, Bi, W, Grimwade, D, Pallisgaard, N, Barbany, G, Cazzaniga, G, Cayuela, J M, Cavé, H, Pane, F, Aerts, J L E, De Micheli, D, Thirion, X, Pradel, V, González, M, Viehmann, S, Malec, M, Saglio, G, and van Dongen, J J M

Published
2003
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18. The ethical approach to AIDS: a bibliographical review

Author

Manuel, C., Enel, P., Charrel J., Reviron, D., Larher, M.P., Thirion, X., and Sanmarco, J.L.

Subjects
HIV infection -- Bibliography, AIDS (Disease), Health, Philosophy and religion
Abstract

This bibliographical study involved first the exploitation of four data-banks: Medline, CNRS, Bioethics and AIDS, with the following key words (in conjunction with AIDS): ethics, human rights, confidentiality, legislation, jurisprudence. A total of 412 references were listed between 1983 and the end of 1987. Examination of the quantitative increase of articles over these years shows that, while references to AIDS and/or HIV infection -- referred to as 'AIDS' for brevity -- increased by about one third per year, the number of papers treating ethical problems linked to AIDS doubled each year. This increase makes it clear that these problems are important and pressing, that they are evolving rapidly and can be given no easy solution. After reading and analysis of accessible articles in readily comprehensible languages, the different themes can be classified in two categories:

Published
1990

20. Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe AgainstCancer program

Author

Gabert, J., Beillard, E., van der Velden, VH., Bi, W., Grimwade, D., Pallisgaard, N., Barbany, G., Cazzaniga, G., Cayuela, J.M., Cave, H., Pane, F., Aerts, J.L., De Micheli, D., Thirion, X., Pradel, V., Gonzalez, M., Viehmann, S., Malec, M., Saglio, G., and van Dongen, J.J

Published
2003

27. Excellent contrôle biochimique chez les patients de plus de 70 ans atteints d’un cancer de la prostate à haut risque après radiothérapie conformationnelle et hormonothérapie adjuvante intermédiaire

Author

Padovani, L., primary, Guerder, C., additional, Bastide, C., additional, Badinand, D., additional, Rossi, D., additional, Thirion, X., additional, Coulange, C., additional, Lechevallier, E., additional, Cowen, D., additional, and Muracciole, X., additional

Published
2009
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36. [Gangrene of the perineum. Plea for a standardized therapeutic management apropos of 50 cases]

Author

Brunet C, JEAN ROBERT DELPERO, Guerinel G, Geissler A, Barthélémy A, Jm, Sainty, Thirion X, and Grégoire R

Subjects
Adult, Aged, 80 and over, Male, Hyperbaric Oxygenation, Middle Aged, Perineum, Gangrene, Survival Rate, Clinical Protocols, Debridement, Predictive Value of Tests, Colostomy, Humans, Female, Aged
Abstract

From 1988 to 1992, 50 cases of perineal gangrene were treated with a therapeutic protocol combining: a) repeated extensive excisions, b) hyperbaric oxygen therapy, even before surgery if this was possible, and c) intensive care. The mortality rate was 24% (12/50). It was even higher in patients admitted more than 6 hours after diagnosis. The average stay in hospital was of 20 (+/- 2) days. Four patients presented with residual signs. Twenty-eight (56%) had had colostomy for lesions originating in the rectum or threatening the anal margin; 9 of these patients died, while gastrointestinal continuity was restored in another 17 cases. There were three predictive factors of survival in this series: a) early diagnosis and treatment, b) severity index on admission, c) some associations of bacteria.

Published
1992

39. Detection of signals of abuse and dependence applying disproportionality analysis.

Author

Pauly, V., Lapeyre-Mestre, M., Braunstein, D., Rueter, M., Thirion, X., Jouanjus, E., and Micallef, J.

Subjects
SUBSTANCE abuse risk factors, DRUG addiction risk factors, CONFIDENCE intervals, DATABASES, MEDICAL information storage & retrieval systems, PSYCHIATRIC drugs, DATA analysis software, DESCRIPTIVE statistics
Abstract

Introduction: Prescription drug abuse and dependence is a widespread phenomenon in many countries. The use of disproportionality measures in drug abuse surveillance is rarely performed. Purpose: The aim of this study is to determine the occurrence of signals of abuse and dependence for different psychoactive drugs in real-life settings. Methods: Disproportionality analysis was realised from a database specifically constructed for the monitoring of drug abuse and dependence. This database provides information on approximately 5000 patients and 8000 consumption modalities for more than 100 distinct psychoactive medications for 2010 and 2011. Proportional reporting ratio (PRR) was computed in two population groups: subjects under an opiate maintenance treatment (OMT) versus those not under OMT, and focused on four types of behaviours: abuse and dependence, illegal acquisition, diverted route of administration and concomitant alcohol use. Results: Among the 100 psychoactive drugs for which a signal could be detected, those presenting the highest signals were the following: flunitrazepam, clonazepam, methylphenidate, ketamine, morphine sulfate, codeine and buprenorphine. Conclusions: The present study shows an innovative application of disproportionality measures for drug abuse monitoring based on two cross-national, annual studies. The disproportionality analysis provided the opportunity to reveal and compare the magnitude of signals between 100 psychoactive drugs. This approach helps to compare the magnitude of abuse and dependence behaviours for a large number of drugs, and allows prioritizing actions in a context where such events are usually underreported. [ABSTRACT FROM AUTHOR]

Published
2015
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40. 2296

Author

Padovani, L., primary, Lechevallier, E., additional, Bastide, C., additional, Badinand, D., additional, Rossi, D., additional, Thirion, X., additional, Coulange, C., additional, Cowen, D., additional, and Muracciole, X., additional

Published
2006
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