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The objective of the study was to assess patient-reported preferences and outcomes in patients rehabilitated with both an implant-supported single crown (ISC) and a tooth-supported fixed dental prosthesis (FDP). The electronic journal system at the Faculty of Dentistry, University of Oslo, was searched to find patients presenting both an ISC and an FDP replacing no more than two teeth between abutments. Identified patients that agreed answered a questionnaire followed by a clinical examination. Descriptive statistics was calculated. Thirty patients were included. The mean function time was 11.8 years for FDPs and 6.6 years for ISCs. All but three patients were satisfied with both rehabilitation modalities. No patients were unsatisfied with aesthetics or function of either rehabilitation. All patients reported satisfactory function of their restorations and reported chewing without problems. The self-reported post-operative complications were few, but less than observed in the clinical examinations. More patients reported food impaction with their FDP as compared to their ISC. Function and aesthetics of FDPs and ISCs were rated similarly, but more patients found the ISC treatment more uncomfortable. Despite this finding, most patients would prefer to undergo ISC treatment if they were to replace another missing tooth. [ABSTRACT FROM AUTHOR]

Objectives: To evaluate osteogenic markers and alveolar ridge profile changes in guided bone regeneration (GBR) of chronic noncontained bone defects using a nonresorbable TiO2 block. Materials and Methods: Three buccal bone defects were created in each hemimandible of eight beagle dogs and allowed to heal for 8 weeks before GBR. Treatment was assigned by block randomization: TiO2 block: TiO2‐scaffold and a collagen membrane, DBBM particulates: Deproteinized bovine bone mineral (DBBM) and a collagen membrane, Empty control: Only collagen membrane. Bone regeneration was assessed on two different healing timepoints: early (4 weeks) and late healing (12 weeks) using several immunohistochemistry markers including alpha‐smooth muscle actin (α‐SMA), osteopontin, osteocalcin, tartrate‐resistant acid phosphatase, and collagen type I. Histomorphometry was performed on Movat Pentachrome‐stained and Von Kossa/Van Gieson‐stained sections. Stereolithographic (STL) models were used to compare alveolar profile changes. Results: The percentage of α‐SMA and osteopontin increased in TiO2 group after 12 weeks of healing at the bone‐scaffold interface, while collagen type I increased in the empty control group. In the defect area, α‐SMA decreased in the empty control group, while collagen type I increased in the DBBM group. All groups maintained alveolar profile from 4 to 12 weeks, but TiO2 group demonstrated the widest soft tissue contour profile. Conclusions: The present findings suggested contact osteogenesis when GBR is performed with a TiO2 block or DBBM particulates. The increase in osteopontin indicated a potential for bone formation beyond 12 weeks. The alveolar profile data indicated a sustained lateral increase in lateral bone augmentation using a TiO2 block and a collagen membrane, as compared with DBBM and a collagen membrane or a collagen membrane alone. [ABSTRACT FROM AUTHOR]

Objectives: To evaluate osteogenic markers and alveolar ridge profile changes in guided bone regeneration (GBR) of chronic noncontained bone defects using a nonresorbable TiO 2 block., Materials and Methods: Three buccal bone defects were created in each hemimandible of eight beagle dogs and allowed to heal for 8 weeks before GBR. Treatment was assigned by block randomization: TiO 2 block: TiO 2 -scaffold and a collagen membrane, DBBM particulates: Deproteinized bovine bone mineral (DBBM) and a collagen membrane, Empty control: Only collagen membrane. Bone regeneration was assessed on two different healing timepoints: early (4 weeks) and late healing (12 weeks) using several immunohistochemistry markers including alpha-smooth muscle actin (α-SMA), osteopontin, osteocalcin, tartrate-resistant acid phosphatase, and collagen type I. Histomorphometry was performed on Movat Pentachrome-stained and Von Kossa/Van Gieson-stained sections. Stereolithographic (STL) models were used to compare alveolar profile changes., Results: The percentage of α-SMA and osteopontin increased in TiO 2 group after 12 weeks of healing at the bone-scaffold interface, while collagen type I increased in the empty control group. In the defect area, α-SMA decreased in the empty control group, while collagen type I increased in the DBBM group. All groups maintained alveolar profile from 4 to 12 weeks, but TiO 2 group demonstrated the widest soft tissue contour profile., Conclusions: The present findings suggested contact osteogenesis when GBR is performed with a TiO 2 block or DBBM particulates. The increase in osteopontin indicated a potential for bone formation beyond 12 weeks. The alveolar profile data indicated a sustained lateral increase in lateral bone augmentation using a TiO 2 block and a collagen membrane, as compared with DBBM and a collagen membrane or a collagen membrane alone., (© 2022 The Authors. Clinical Implant Dentistry and Related Research published by Wiley Periodicals LLC.)

The aim of the study was to perform comprehensive characterization of two commonly used bulk fill composite materials (SDR Flow (SDR) and Filtek™ Bulk Fill Flowable Restorative (FBF) and one conventional composite material (Tetric EvoCeram; TEC). Eleven parameters were examined: flexural strength (FS), flexural modulus (FM), degree of conversion, depth of cure, polymerisation shrinkage (PS), filler particle morphology, filler mass fraction, Vickers hardness, surface roughness following simulated toothbrush abrasion, monomer elution, and cytotoxic reaction of human gingival fibroblasts, osteoblasts, and cancer cells. The degree of conversion and depth of cure were the highest for SDR, followed by FBF and TEC, but there was no difference in PS between them. FS was higher for bulk fill materials, while their FM and hardness were lower than those of TEC. Surface roughness decreased in the order TEC→SDR→FBF. Bisphenol A-glycidyl methacrylate (BisGMA) and urethane dimethacrylate were found in TEC and FBF eluates, while SDR released BisGMA and triethylene glycol dimethacrylate. Conditioned media accumulated for 24h from FBF and TEC were cytotoxic to primary human osteoblasts. Compared to the conventional composite, the tested bulk fill materials performed equally or better in most of the tests, except for their hardness, elastic modulus, and biocompatibility with osteoblasts.