1. Epidemic outbreaks in structured host populations
- Author
-
Thieme, Horst R
- Subjects
Quantitative Biology - Populations and Evolution ,Mathematics - Analysis of PDEs ,92D30, 92D25, 28A25, 45H05, 45M99, 47J05, 47N20 - Abstract
For a heterogeneous host population, the basic reproduction number of an infectious disease, $\cR_0$, is defined as the spectral radius of the next generation operator (NGO). The threshold properties of the basic reproduction number are typically established by imposing conditions that make $\cR_0$ an eigenvalue of the NGO associated with a positive eigenvector and a positive eigenfunctional (eigenvector of the dual of the NGO). More general results can be obtained by imposing conditions that associate $\cR_0$ just with a positive eigenfunctional. The next generation operator is conveniently expressed by a measure kernel or a Feller kernel which enables the use of analytic rather than functional analytic methods., Comment: 47 pages
- Published
- 2024