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411 results on '"Thiazepines therapeutic use"'

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1. Severe tianeptine withdrawal symptoms managed with medications for opioid use disorder: a case report.

2. Microdose Induction of Buprenorphine in a Patient Using Tianeptine.

3. Rationale and design of a multicentre, 12-week, randomised, double-blind, placebo-controlled, parallel-group, investigator-initiated trial to investigate the efficacy and safety of elobixibat for chronic constipation.

4. Impact of elobixibat on serum and fecal bile acid levels and constipation symptoms in patients with chronic constipation.

5. Safety of elobixibat and lubiprostone in Japanese patients with chronic constipation: a retrospective cohort study.

6. Tianeptine modulates synaptic vesicle dynamics and favors synaptic mitochondria processes in socially isolated rats.

7. Selective Inhibition of the C-Domain of ACE (Angiotensin-Converting Enzyme) Combined With Inhibition of NEP (Neprilysin): A Potential New Therapy for Hypertension.

8. Effectiveness of tianeptine in patients with major depressive disorder and substance use disorder.

9. Gut-restricted apical sodium-dependent bile acid transporter inhibitor attenuates alcohol-induced liver steatosis and injury in mice.

10. Evaluation of Small Molecule Combinations against Respiratory Syncytial Virus In Vitro.

11. Elobixibat, an ileal bile acid transporter inhibitor, ameliorates non-alcoholic steatohepatitis in mice.

12. Modulation of atypical brain activation during executive functioning in autism: a pharmacological MRI study of tianeptine.

13. Real-World Comparison of Elobixibat and Lubiprostone Treatment in Patients with Chronic Constipation: A Propensity Score-Matched Analysis.

14. The benefit of elobixibat in chronic constipation is associated with faecal deoxycholic acid but not effects of altered microbiota.

15. Activation syndrome induced by the antidepressant tianeptine and suicidal ideation: Evidence from a large depressed outpatient sample.

16. Elobixibat alleviates chronic constipation in hemodialysis patients: a questionnaire-based study.

17. Influence of the CB 1 and CB 2 cannabinoid receptor ligands on the activity of atypical antidepressant drugs in the behavioural tests in mice.

19. Discovery of Ziresovir as a Potent, Selective, and Orally Bioavailable Respiratory Syncytial Virus Fusion Protein Inhibitor.

20. Tianeptine, an atypical pharmacological approach to depression.

21. Maternal separation induces long-term changes in mineralocorticoid receptor in rats subjected to chronic stress and treated with tianeptine.

22. Efficacy, long-term safety, and impact on quality of life of elobixibat in more severe constipation: Post hoc analyses of two phase 3 trials in Japan.

23. Adjunctive tianeptine treatment for bipolar disorder: A 24-week randomized, placebo-controlled, maintenance trial.

24. Discovery and anti-inflammatory evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β).

25. Effect of single and multiple doses of elobixibat, an ileal bile acid transporter inhibitor, on chronic constipation: A randomized controlled trial.

26. Elobixibat for the treatment of constipation.

27. Safety and efficacy of elobixibat for chronic constipation: results from a randomised, double-blind, placebo-controlled, phase 3 trial and an open-label, single-arm, phase 3 trial.

28. Elobixibat, the first-in-class Ileal Bile Acid Transporter inhibitor, for the treatment of Chronic Idiopathic Constipation.

29. Work in Progress: Drugs in Development.

30. Efficacy of Tianeptine 25-50 mg in Elderly Patients With Recurrent Major Depressive Disorder: An 8-Week Placebo- and Escitalopram-Controlled Study.

31. Management of Chronic Hepatic Itch.

32. Determining an optimal clinical dose of elobixibat, a novel inhibitor of the ileal bile acid transporter, in Japanese patients with chronic constipation: a phase II, multicenter, double-blind, placebo-controlled randomized clinical trial.

33. Tianeptine is associated with lower risk of suicidal ideation worsening during the first weeks of treatment onset compared with other antidepressants: A naturalistic study.

34. Opioid Receptors Contribute to Antinociceptive Effect of Tianeptine on Colorectal Distension-Induced Visceral Pain in Rats.

35. Targeting Mitochondrial Calcium Handling and Reactive Oxygen Species in Heart Failure.

36. Effect of ileal bile acid transporter inhibitor GSK2330672 on pruritus in primary biliary cholangitis: a double-blind, randomised, placebo-controlled, crossover, phase 2a study.

37. ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia.

38. Treatment of catecholaminergic polymorphic ventricular tachycardia in mice using novel RyR2-modifying drugs.

39. The effect of chronic tianeptine administration on the brain mitochondria: direct links with an animal model of depression.

40. Effects of JTV-519 on stretch-induced manifestations of mechanoelectric feedback.

41. Differential effects of tianeptine on the dorsal hippocampal volume of rats submitted to maternal separation followed by chronic unpredictable stress in adulthood.

42. Effects of tianeptine on the development and maintenance of mechanical allodynia in a rat model of neuropathic pain.

43. Patient-Specific Human Induced Pluripotent Stem Cell Model Assessed with Electrical Pacing Validates S107 as a Potential Therapeutic Agent for Catecholaminergic Polymorphic Ventricular Tachycardia.

44. BAT117213: Ileal bile acid transporter (IBAT) inhibition as a treatment for pruritus in primary biliary cirrhosis: study protocol for a randomised controlled trial.

45. Tianeptine, olanzapine and fluoxetine show similar restoring effects on stress induced molecular changes in mice brain: An FT-IR study.

46. Combined Angiotensin Receptor Antagonism and Neprilysin Inhibition.

47. The two faces of hypertension: role of aortic stiffness.

48. Childhood constipation: finally something is moving!

49. Increased libido associated with donepezil treatment: a case report.

50. Influence of anxiety symptoms on improvement of neurocognitive functions in patients with major depressive disorder: A 12-week, multicenter, randomized trial of tianeptine versus escitalopram, the CAMPION study.

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