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Purpose The association between alcohol consumption and pancreatic cancer is unsettled. Methods Altogether 243,169 men and women 20–79 years, without cancer at baseline, were followed with respect to pancreatic cancer by linkage to the Cancer Registry of Norway and the Norwegian Cause of Death Registry. They participated in a cardiovascular survey where information on alcohol consumption, smoking habits, anthropometric measures, and some biological variables were recorded. During 20 years of follow-up, 991 incident pancreatic cancers were registered. We estimated the hazard ratios with the Cox proportional hazards model, and graphed spline curves between glass-units/d of alcohol and hazard ratio of incident pancreatic cancer. Results The multivariable adjusted hazard per 1 glass-unit/d was 1.08 (95% confidence interval 1.02–1.15) for men and 1.04 (0.97–1.13) for women. The association between alcohol consumption and incident pancreatic cancer was present in ex- and current smokers, but the association could be ascribed to smoking habits. The multivariable adjusted spline curves increased with increasing glass-units/d and with confidence bands not encompassing 1.0 above one glass-unit/day. Conclusion Our findings of an association between higher level of alcohol consumption and incident pancreatic cancer, could be attributed to confounding by smoking habits. Alcohol consumption and incidence of pancreatic cancer

The papers of the report are not available in Munin: 1. Thelle DS, Førde OH, Try K, Lehmann EH: ‘The Tromsø heart study. Methods and main results of the cross-sectional study’. Acta Med Scand. 1976;200(1-2):107-118. Available at http://dx.doi.org/10.1111/j.0954-6820.1976.tb08204.x 2. Førde OH, Thelle DS:‘The Tromsø heart study. A multiple regression analysis of the relationship between coronary risk factors and some physical and social variables’. Scand J Public Health March 1980 vol. 8 no. 2 49-54. 3.OLAV H. FØRDE and DAG S. THELLE: ‘THE TROMSOØ HEART STUDY: RISK FACTORS FOR CORONARY HEART DISEASE RELATED TO THE OCCURRENCE OF MYOCARDIAL INFARCTION IN FIRST DEGREE RELATIVES’. Am. J. Epidemiol. (1977) 105 (3):192-199. 4. Thelle DS, Førde OH.: The cardiovascular study in Finnmark county: coronary risk factors and the occurrence of myocardial infarction in first degree relatives and in subjects of different ethnic origin. This is the manuscript version of the article. Published version in ‘Am J Epidemiol. 1979, 110(6):708-15'. 5. Dag S. Thelle, Olav H. Førde, Egil Arnesen: ‘The Tromsø heart study: A model for describing family-associated risk for coronary heart disease as a continuous variable’. (Manucript). 6. O. D. Mjøs, D. S. Thelle, O. H. Førde and H. Vik-Mo: ‘Family Study of High Density Lipoprotein Cholesterol and the Relation to Age and Sex’. This is the manuscript version of the article. Published version in ‘Acta Medica Scandinavica, 1977, Volume 201, Issue 1-6, pages 323–329’. Available at http://dx.doi.org/10.1111/j.0954-6820.1977.tb15707.x 7.Miller NE, Thelle DS, Forde OH, Mjos OD.: ‘The Tromsø heart-study. High-density lipoprotein and coronary heart-disease: a prospective case-control study’. The Lancet, Volume 309, Issue 8019, 7 May 1977, Pages 965–968. Available at http://dx.doi.org/10.1016/S0140-6736(77)92274-7 8. O. H. Førde, D. S. Thelle, N. E. Millerand, and O. D. Mjøs:’ Distribution of Serum Cholesterol between High Density and Lower Density Lipoproteins in Subjects of Norse, Finnish and Lappish Ethnic Origin’. Acta Medica Scandinavica, 1078, Volume 203, Issue 1-6, pages 21–26. Available at http://dx.doi.org/10.1111/j.0954-6820.1978.tb14825.x