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In July 1998, a telemedicine link was established between the Venizelio General Hospital in Crete and the Paediatric Cardiology Department of the Aghia Sophia Children's Hospital in Athens. The telemedicine link used ISDN at 384 kbit/s for diagnosis, management and education in congenital heart disease. Over 18 months, a total of 39 teleconsultations were carried out, concerning 93 children with haemodynamically significant cardiac abnormalities. Forty-four children (47%) were managed locally after teleconsultation, while three children with transposition of the great arteries (3%) were transported as emergency cases to Athens in the first days of life. The other 46 children (50%) had a scheduled appointment at a tertiary centre for cardiac catheterization, angiocardiography, operative treatment or surgical repair. The telemedicine link brought a number of benefits, such as better access to the tertiary centre and the avoidance of patient transportation. [ABSTRACT FROM AUTHOR]

The COVID-19 pandemic and associated lockdowns triggered worldwide changes in the daily routines of human experience. The Blursday database provides repeated measures of subjective time and related processes from participants in nine countries tested on 14 questionnaires and 15 behavioural tasks during the COVID-19 pandemic. A total of 2,840 participants completed at least one task, and 439 participants completed all tasks in the first session. The database and all data collection tools are accessible to researchers for studying the effects of social isolation on temporal information processing, time perspective, decision-making, sleep, metacognition, attention, memory, self-perception and mindfulness. Blursday includes quantitative statistics such as sleep patterns, personality traits, psychological well-being and lockdown indices. The database provides quantitative insights on the effects of lockdown (stringency and mobility) and subjective confinement on time perception (duration, passage of time and temporal distances). Perceived isolation affects time perception, and we report an inter-individual central tendency effect in retrospective duration estimation., (© 2022. The Author(s), under exclusive licence to Springer Nature Limited.)

Past studies have shown that when a voluntary action produces a sensory effect, the action and the effect will be perceived as being closer in time. This subjective temporal 'attraction' is known as intentional binding (IB). Induction of IB is dependent on the intentionality of one's actions, the predictability of the effect, and the causality between the action and the effect. Previous investigations of IB have utilized abstract stimuli (e.g., flashes and beeps) with adaptation so as to associate the abstract action-effect link. Yet, events from our everyday experiences already have an inherent action-effect link. We, thus, investigated, for the first time, IB under naturalistic, multisensory stimulation by manipulating the intentionality, predictability, and causal event link. A total of five experiments without adaptation were conducted examining IB with: abstract stimuli (Experiment 1), naturalistic effects (Exp. 2), naturalistic action cue and effect matching (Exp. 3), naturalistic action cue and effect mismatching (Exp. 4), and naturalistic action cue and effect matching but mismatched response mapping (Exp. 5). Analyses of the data showed the absence of IB for abstract stimuli without action-effect adaptation (Exp. 1) and for effects that were not inherently causal or predictable of one's action (Exp. 2, 4, and 5). IB, however, was induced when the naturalistic sequence of action cue-effect was casually linked and predictable in terms of timing (Exp. 3). Overall, our results showed that induction of IB is dependent on the inherent causal and predictable association of an event from the cue to act to the consequence of that action, an association that is already present in everyday multisensory events., (Copyright © 2018 Elsevier B.V. All rights reserved.)

Numerous technical modifications and various complications of the Senning procedure have been described in the literature. We describe the excellent clinical status and anatomic result of a 33-year-old patient who underwent a modified Senning operation using the left atrial appendage for reconstruction more than 30 years prior to presentation.

Background: Coarctation of aorta (CoA) patients present cardiovascular complications late after repair the causes of which are not fully understood. Our study investigates the neurohormonal and immune activation and the elastic properties of the aorta and peripheral vessels in adult patients with coarctation of aorta (CoA), late after repair., Methods: Nineteen adult patients with repaired CoA and 29 matched healthy controls underwent aortic distensibility, stiffness index, a study of the elastic properties of peripheral vessels proximal to the coarctation site and measurement of plasma cytokine and neurohormone levels., Results: Distensibility index was reduced (p=0.02) and stiffness index was increased (p=0.005) in CoA patients compared to control. Augmentation index (p=0.0007) and augmented pressure (p=0.001) were higher in CoA patients and Forearm Blood Flow (FBF) index was reduced (p=0.009). Plasma levels of sICAM-1 (p=0.01), sVCAM-1 (p=0.05), E-selectin (p=0.01), sFas-ligand (p=0.02) and IL-10 (p=0.01) were also elevated in CoA patients vs control. TNF-a, IL-6, Endothelin-1 and NT-pro-BNP levels were not., Conclusions: Adults with repaired CoA seem to develop a late inflammatory reaction, which reflects a functional problem in all vessels, regardless of the initial lesion. This may explain the late complications of the disease despite early repair and improved surgical procedures., (Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.)

The aim of this study was to determine the differences in the kinematic parameters between the grab and track starts and the differences in these two starts between genders. A total of 27 swimmers at the competitive level participated in the study, 13 boys (mean ± SD: age 15.8 ± 0.8 years, body mass 67.7 ± 7.7 kg and body height 178.6 ± 5.7 cm) and 14 girls (mean ± SD: age 16 ± 0.8 years, body mass 59.2 ± 6.6 kg and body height 166.2 ± 6.7 cm). Each swimmer performed three attempts for both start techniques. The best attempt of the grab start and the track start was taken for further analysis. The following kinematic parameters were analysed: flight distance, flight time, flight velocity, entry angle and reaction time. The males had greater numeric values for the results in all kinematic parameters for the grab start compared with the track start, except for flight velocity and entry angle (flight time 0.42 vs. 0.41 s, flight distance 3.21 vs. 3.14 m, flight velocity 7.76 vs. 7.83 m/s, entry angle 44.22 vs. 43.85 degrees and reaction time 0.86 vs. 0.81 s). The females also had greater numeric values for the results in all kinematic parameters for the grab start compared with the track start, except for flight time (flight time 0.38 vs. 0.38 s, flight distance 2.82 vs. 2.73 m, flight velocity 7.47 vs. 7.31 m/s, entry angle 45.18 vs. 44.79 degrees and reaction time 0.88 vs. 0.82 s). These results indicate that the males had significantly better results for flight time and flight distance compared with the females for the grab start (flight time 0.42 vs. 0.38 s, flight distance 3.21 vs. 2.82 m). In the case of the track start, the males had significantly better results for flight distance (3.14 vs. 2.73 m). Exploring the characteristics of the two starts did not lead to any significant kinematic differences. Therefore, a conclusion that demonstrates the superiority of one of the techniques cannot be reached. The coach, together with each swimmer individually, should devote some time to decide after some tests what type of start is better for the body type and general qualifications of the swimmer.

We present the case of a patient who underwent a percutaneous secundum atrial septal defect (ASD II) closure with an undersized septal occluder device. One week and one month later she experienced two transient ischemic attacks. Three-dimensional transesophageal echocardiography (TEE) revealed a residual patent foramen ovale (PFO) with a positive Valsalva bubble test. She underwent a second procedure under the 3D TEE guidance and the PFO was successfully closed percutaneously using a PFO occluder device that was attached to the ASD device. Accurate ASD and PFO morphology assessment and appropriate device selection are the key factors in the success of percutaneous closure. 3D TEE is an innovative diagnostic technique, providing a complete description of the cardiac defect and improving spatial orientation. Real-time 3D TEE is the appropriate guidance for successful and accurate positioning of the device.

Introduction: Inflammation and neurohormonal activation are considered to be involved in the development of earlier and/or later complications in congenital heart disease patients, even after a successful repair of the lesion. It is not yet clarified what is the role of the therapeutic interventions in the occurrence of such a response and how it could be associated with possible postoperative complications., Aim: We sought to assess the inflammatory and neurohormonal response to transcatheter closure of secundum type atrial septal defects (ASD) over a six-month follow-up period. We also evaluated the association between the respective markers and catheterization data as well as echocardiographic measurements., Methods: Plasma concentrations of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), interleukin-10 (IL-10), N-terminal-proatrial natriuretic peptide (NT-proANP) and N-terminal-probrain natriuretic peptide (NT-proBNP) were assessed and echocardiographic measurements were performed in twenty-eight patients with atrial septal defect prior to, and at the first, second and sixth months post transcatheter closure. Thirty-three age-matched healthy volunteers were also enrolled., Results: IL-6 plasma levels, although higher preoperatively, [physical logarithm (ln) IL-6: 3.37±0.66 vs 2.92±0.44 pg/ml, p=0.015], reached control levels postoperatively, at the end of the third month, whereas TNF-α and IL-10 were not influenced by the procedure. NT-proANP levels were elevated preoperatively compared to the control group (ln NT-proANP 3.78±0.572 vs 3.48±0.30, p=0.031), with a further significant increase during the 1st month (ln NT-proANP 3.78±0.572 vs 4.2±0.42, p=0.006), following the pattern of the left atrial volume enlargement, and remained high even 6 months after the procedure .On the other hand, the initially normal concentrations of NT-proBNP, after a transient significant increase during the first month postoperatively (ln NT-proBNP 3.56±0.94 vs 4.58±0.91, p<0.0001) returned to the controls' levels at the end of the third month. Preoperative concentrations of NT-proANP positively correlated with NT-proBNP concentrations and pulmonary to systemic flow ratio (Qp/Qs)., Conclusions: Transcatheter closure could improve, on a mid- term basis, the inflammatory process but natriuretic peptides' secretion continues in parallel with left atrial volume increase. Further follow up is required to determine the long-term progress of the inflammatory and neurohormonal response to the procedure., (Copyright © 2011 Elsevier Ltd. All rights reserved.)