22 results on '"Thanni, L."'
Search Results
2. Exercise Modulation of Blood Pressure, Respiratory Rate and Pulse Rate in Undergraduate Students
- Author
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O., Taiwo E., primary and A., Thanni L. O., additional
- Published
- 2021
- Full Text
- View/download PDF
3. Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial
- Author
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Brenner, A., Belli, A., Chaudhri, R., Coats, T., Frimley, L., Jamaluddin, S. F., Jooma, R., Mansukhani, R., Sandercock, P., Shakur-Still, H., Shokunbi, T., Roberts, I., Aeron-Thomas, A., Chaudary, M. A., Jamaluddin, S. F. B., Javaid, K., Kayani, A., Leech, C., Mahmood, K., Noor, J. M., Mejia-Mantilla, J., Moss, P., Pott, J., Vallecilla, L., Hartzenberg, H. B., Joshipura, M., Perel, P., Clarke, M. J., Ohaegbulam, S. C., Rodgers, A., Brady, T., Dewan, Y., Edwards, P., Komolafe, E. O., Arribas, M., Austin, E., Balogun, E., Barneston, L., Barrow, C., Beaumont, D., Benyahia, M., Brooks, I., Cargill, M., Carrington, L., Cook, L., Cornu-Hewitt, B., Geer, A., Gilbert, D., Gilliam, C., Gil-Onandia, J., Hetherington, D., Howe, C., Hughes, C., I'Anson, D., Jackson, R., Joshi, M., Kansagra, S., Kawahara, T., Ker, K., Kostrov, S., Mahmood, A., Miah, H., Ndungu, B., Needham, K., Okusi, C., Outtandy, A., Pardinaz-Solis, R., Pearson, D., Pepple, T., Pisani, C., Prieto-Merino, D., Prowse, D., Quashi, N., Quinn, A., Ramos, M., Reid, M., Roukas, C., Scrapa, G., Squires, C., Tanner, J., Thayne, A., Vidaurre, L., Woods, E., Fawole, B., Adetayo, O., Okunade, O., Gogichaishvili, T., de los Angeles Munoz-Sanchez, M., Olldashi, F., Krishnan, S., Djientcheu, V., Castellanos, J. L., Rasulo, F., Hama, Q., Mulla, Y., Florian, I. S., Tobar, J., Khamis, H., Deasy, C., Wellsh, B., Williams-Johnson, J., Chandra, S., Mutiso, V., Butt, R., Nasir, M. H., Ahmad, S., Aslam, F., Ishaque, K., Usmani, F., Rizvi, S., Ali, F., Sajjad, O., Zunair, A., Rehman, L., Rizvi, R., Javeed, F., Ahmed, S., Abbas, A., Afzal, A., Mikdad, A., Bashir, A., Chaudary, A., Salahuddin, T., Ahemed, B., Aziz, A., Ashraf, N., Hussain, S., Ahmad, U., Asif, M., Adil, M., Rauf, A., Khan, R., Ahmad, B., Afzal, U., Raza, H., Ain, Q., Yaqoob, S., Waseem, Q., Nishat, M., Semvel, S., Iqbal, J., Majeed, S., Zulfiqar, S., Iqbal, M., Majeed, N., Ahmed, M., Akhtar, N., Malik, M., Shehzad, Y., Yousaf, M., Wahid, A., Samad, A., Shah, S., Ali, M., Zeb, J., Khan, A. S., Irfan, A., Sharif, S., Memon, R., Bloom, B., Harris, T., Skene, I., Bellhouse, G., Boulton, O., Ward, G., Jarvis, C., Swann, C., Ratnam, S., Carrera, R., Yakoub, K., Davies, D., Fellows, E., Jarman, H., Rounding, S., Johnson, E., Loughran, C., Lecky, F., Clayton, K., Michael, A., Coumbarides, A., Kendall, J., Faulkner, B., Worner, R., Gendall, E., Hopkins, P., Riozzi, P., Cotton, H., Astin-Chamberlain, R., Wilson, M., Bodnar, J., Williams, R., Rigoni, A., Sattout, A., Fletcher, J., Edge, C., Maryanji, N., Boyle, A., Hardwick, S., Nichols, E., Hayhurst, C., Coffey, F., Gough, C., Miller, P., Ryan, L., Darwent, M., Espinosa, A., Beer, S., Norton, J., Maguire, H., Finney, K., Kehoe, A., Squire, R., Jeffery, A., Vorwerk, C., Foord, D., Wilkinson, E., Kuhrt, A., Ramlakhan, S., Reid, S., Curran, A., Mcmullan, S., Hassan, T., Nuttall, S., Haig, S., Al-Nahhas, S., Bulters, D., Zolnourian, A., Ribbons, T., Mew, I., de Weymarn, T., Hughes, V., Mcvicar, J., Mckiernan, C., Keating, L., Reschreiter, H., Wright, J., Chan, L., Kataria, H., Ireland, A., Body, R., Corfield, A., Francis, S., Townend, W., Gagg, J., Wilson, S., Cottingham, R., Tucker, S., Sutherland, F., Mitchell, L., Parker, L., Afolabi, O., Hunter, F., Jadav, M., Adeboye, K., Grocutt, M., May, G., Watson, D., Wootten, A., Robertshaw, S., Dorrian, S., Perry, R., Choi, H., Mcgroarty, C., Shone, P., Maritz, D., Jamaluddin, S., Noor, J., Rosli, N., Xian, L. L. S., De Jun, Y., Mohamed, F., Song, C. H., Hawari, A., Chin, L. Y., Hussein, H. M., Lotfi, M., Hamid, H., Udin, N., Lian, P., Choo, S., Wong, K., Gani, F., Jusoh, M., Rajakumar, D., Yang, C. B., Dzulkiflee, N. S. B., W. C., Ky, Azman, M. A. B. M., Osman, A. B., Ahmad, A. H., Ismail, R., Lai, S. Q., Mohidin, M. A. B., Deraman, N. B., Selamat, S. B., Abidin, I., Halim, N., Bakar, Z., Ismail, Z. M., Hisham, B., Kamal, R., Effendy, Z., Ismail, M., Azleen, N., Seng, L. Y., Baharuddin, K. A., Kandasamy, R., Kamalludin, A., Asmee, S., Fadzil, M., Basitz, A., Abdullah, N., Ingorokva, G., Ingorokva, S., Agdgomelashvili, I., Mumladze, K., Maisuradze, I., Kugusheva, I., Shalamberidze, B., Tomadze, G., Fernandez-Ortega, J., Seara-Valero, R., Ibanez-Botella, G., Garcia-Martinez, V., Martul, M. G., Ramos, S. F., Preciado, G. L., Garcia-Alfaro, C., Munoz-Sanchez, A., Bellido-Alba, R., Corcobado, C., Bueno, A., Ambros, A., Jimenez, J. T., Ramirez, J. R., Martin, J., Rodriguez, L. I., Fontanals, J., Jimenez-Moragas, J. M., Berbegal, J. P., Oluwole, O., Mahmud, R., Ukwu, N., Bankole, F., Oseni, A., Adebayo, B., Malomo, A., Tiamiyu, L., Adekanmbi, A., Thanni, L., Olubodun, A., Ojeblenu, F., Uwaezuoke, M., Komolafe, E., Owagbemi, O., Ishola, F., Durodola, A., Udoffa, U., James, A., Tella, A., Dongo, A., Ekpemiro, U., Anyanwu, S., Aigoro, N., Mezue, W., Shilong, D., Azeez, A., Babalola, O., Ibrahim, M., Obande, J., Franco, A. C., Salazar, E. V., Londono, S. B., Cardona, V. M., Morales, C., Naranjo, S., Agudelo, J., Carvajal, S., Fajardo-Gaviria, Y., Roka, Y., Ghising, U., Roka, N., Shrestha, M., Devkota, U., Vaidya, B., Nepal, P., Thapa, A., Kc, B., Shrestha, A., Jha, R., Shrestha, P., Hodaj, I., Spaho, E., Selaj, A., Bendo, N., Shoko, T., Endo, H., Senda, A., Hagihara, Y., Fuse, T., Masunaga, N., Otomo, Y., Egashira, R., Ohnuki, T., Almazmi, A., Saha, S., Suvarov, A., Aung, T. L., Tun, K. M., Khaing, T. T., Maw, T., Ndome, O., Moumi, M., Mbida, A., Fondop, J., Sebastien, M., Azim, A., Adil, J., Amiry, Z., Loria-Castellanos, J., Rubio, N. G., Leon, P. O., Estrada, F., de Oca-Garcia, E. M., Sanchez, H., Soria, A., Bonucci, P., Franchi, F., Girardini, A., Hameed, H., Basim, M., Stock, S., Hourt, E., Ilunga, A., Mulenga, J., Ples, H., Danil, A., Gorgan, M., Florian, I., Vlahovic, D., French, J., East, J., Kurniawan, A., and Kiboi, J.
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medicine.medical_specialty ,Tranexamic acid ,Traumatic brain injury ,Epidemiology ,Critical Care and Intensive Care Medicine ,Placebo ,CRASH-3 trial ,Neuroprotection ,Intracranial haemorrhage ,law.invention ,Emergence care ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,law ,Internal medicine ,Medicine ,Humans ,030212 general & internal medicine ,Randomised controlled trial ,business.industry ,Multiple Trauma ,Research ,lcsh:Medical emergencies. Critical care. Intensive care. First aid ,030208 emergency & critical care medicine ,lcsh:RC86-88.9 ,Protective Factors ,medicine.disease ,Polytrauma ,Antifibrinolytic Agents ,3. Good health ,Neuroprotective Agents ,Relative risk ,Brain Injuries ,business ,medicine.drug - Abstract
Background The CRASH-3 trial hypothesised that timely tranexamic acid (TXA) treatment might reduce deaths from intracranial bleeding after traumatic brain injury (TBI). To explore the mechanism of action of TXA in TBI, we examined the timing of its effect on death. Methods The CRASH-3 trial randomised 9202 patients within 3 h of injury with a GCS score ≤ 12 or intracranial bleeding on CT scan and no significant extracranial bleeding to receive TXA or placebo. We conducted an exploratory analysis of the effects of TXA on all-cause mortality within 24 h of injury and within 28 days, excluding patients with a GCS score of 3 or bilateral unreactive pupils, stratified by severity and country income. We pool data from the CRASH-2 and CRASH-3 trials in a one-step fixed effects individual patient data meta-analysis. Results There were 7637 patients for analysis after excluding patients with a GCS score of 3 or bilateral unreactive pupils. Of 1112 deaths, 23.3% were within 24 h of injury (early deaths). The risk of early death was reduced with TXA (112 (2.9%) TXA group vs 147 (3.9%) placebo group; risk ratio [RR] RR 0.74, 95% CI 0.58–0.94). There was no evidence of heterogeneity by severity (p = 0.64) or country income (p = 0.68). The risk of death beyond 24 h of injury was similar in the TXA and placebo groups (432 (11.5%) TXA group vs 421 (11.7%) placebo group; RR 0.98, 95% CI 0.69–1.12). The risk of death at 28 days was 14.0% in the TXA group versus 15.1% in the placebo group (544 vs 568 events; RR 0.93, 95% CI 0.83–1.03). When the CRASH-2 and CRASH-3 trial data were pooled, TXA reduced early death (RR 0.78, 95% CI 0.70–0.87) and death within 28 days (RR 0.88, 95% CI 0.82–0.94). Conclusions Tranexamic acid reduces early deaths in non-moribund TBI patients regardless of TBI severity or country income. The effect of tranexamic acid in patients with isolated TBI is similar to that in polytrauma. Treatment is safe and even severely injured patients appear to benefit when treated soon after injury. Trial registration ISRCTN15088122, registered on 19 July 2011; NCT01402882, registered on 26 July 2011.
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- 2020
4. Iatrogenic Arterial Injury And Foot Gangrene A Case Report
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Thanni, L O
- Abstract
Background: Elective orthopaedic operations on the knee is rarely complicated by arterial injury. Report: A case report is presented of a 10year old girl that developed gangrene of the foot following an elective orthopaedic operation on the proximal tibial metaphysis. A transfixion wire that breached the posterior tibial cortex was most probably responsible for popliteal artery injury that resulted in ischaemia and gangrene. The patient had an amputation of all the toes in the affected limb and recovered satisfactory limb function. Conclusion: In operations on the proximal tibial metaphysis, implants (screws, pins, wires) should not be allowed to perforate the posterior cortex. When this occurs inadvertently, they should be readjusted as soon as radiographs confirm this, to avoid injury to the popliteal artery. Keywords: ischaemia, arterial injury, gangrene, amputation, orthopaedic operationNigerian Journal of Clinical Practice Vol. 10 (4) 2007 pp. 352-354
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- 2008
5. CASE REPORTS- Extremity haemangiopericytoma, a case report from Nigeria
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Thanni, L O
- Abstract
Haemangiopericytoma is an uncommon soft tissue sarcoma of vascular origin. It occurs more frequently in the extremities than elsewhere in the body although it can arise in any organ. Wide surgical excision is the mainstay of treatment. However, adjuvant radiotherapy and chemotherapy are desirable because the malignant nature of this tumour is frequently unpredictable. Adjuvant therapy is recommended for metastases, recurrence and incomplete resection. Long term follow up is essential in all cases as recurrence can occur several years after treatment. Where little or no experience with managing this tumor exists, it is important to be aware of its clinical behaviour and the treatment options, hence this case reports. Keywords: haemangiopericytoma, sarcoma, tumour, radiotherapy, chemotherapy African Health Sciences Vol. 5 (3) 2005: pp. 261-264
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- 2007
6. Bacterial osteomyelitis in major sickling haemoglobinopathies: geographic difference in pathogen prevalence
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Thanni, L O
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haemoglobinopathy, osteomyelitis, sickle cell disease, bacteria, salmonella, staphylococcus aureus - Abstract
Background: Controversy exists about the bacterial pathogen that is most often associated with osteomyelitis in major sickling haemoglobinopathies, that is, HbSS, HbSC, and HbSthalassemia. Objective: To determine the existence of regional or continental differences in the prevalence of bacterial pathogens associated with osteomyelitis in sickling haemoglobinopathies Method: A meta-analysis is done of 11 year hospital data set and published studies in African Journals Online (Ajol) and Pubmed electronic databases on the subject. Results: Fifteen studies including two hundred and eighty one bacterial pathogens from SubSaharan Africa, United States, Europe and the Middle East were analysed. There were 129 (45.9%) salmonellae, 82 (29.2%) Staphylococcus aureus, 55 (19.6%) other Gram negative bacilli (GNB) and 15 (5.3%) other Gram positive cocci (GPC). There were 117 isolates in the studies from Africa out of which salmonellae accounted for 21.4%, S. aureus 38.5%, other GNB 34.2% and other GPC 6%. In contrast, out of 110 isolates in the studies from the USA, salmonellae were 70%, S. aureus 16.4%, other GNB 9.1% and other GPC 4.5%. Salmonellae and S. aureus accounted for 37.9% and 62.1%; 64% and 4.9% in isolates from the Middle East and Europe respectively. Conclusions: Salmonellae are the most common bacterial pathogens of osteomyelitis in major sickling haemoglobinopathies in the USA and Europe whereas Staphylococcus aureus is the most common pathogen in SubSaharan Africa and the Middle East. The worldwide prevalence of salmonella may be reducing while that of S. aureus may be increasing. Possible reasons for this observation are suggested. Keywords: haemoglobinopathy, osteomyelitis, sickle cell disease, bacteria, salmonella, staphylococcus aureus > African Health Sciences Vol. 6 (4) 2006: pp. 236-239
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- 2007
7. A ten year review of Paediatric HIV/AIDS among hospitalized children in a Nigerian Teaching Hospital
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Fetuga, M B, primary, Ogunfowora, O B, additional, Oyegunle, V M, additional, and Thanni, L O, additional
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- 2008
- Full Text
- View/download PDF
8. Epidemiology of Severe Injury in a Nigerian Hospital
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Thanni, L OA, primary and Tade, A O, additional
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- 2008
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9. A STUDY OF THE PATTERN, MANAGEMENT AND OUTCOME OF PENETRATING COLON INJURIES IN SAGAMU.
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Tade, A. O., Thanni, L. O. A., and Ayoade, B. A.
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- 2009
10. Extremity amputation in Nigeria -- a review of indications and mortality.
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Thanni, L. O. A. and Tade, A. O.
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AMPUTATION , *MORTALITY , *CANCER , *GANGRENE , *ARTERIAL diseases - Abstract
Amputation is a common surgical procedure in Nigeria but there are no national data on the subject The objective was to determine the common indications for amputation in Nigeria, mortality rate, and regional differences in indications. Results of studies on amputation in Nigeria over a 15-year period were collated and analysed. The most frequent indications for amputation were trauma (34%); complication of traditional bonesetting (TBS) (23%); malignant tumours (14.5%); diabetic gangrene (12.3%); infections (5.1%); peripheral artery disease (2.1%); and bums (2.1%). In the southern regions, trauma is the most common indication while complications of traditional bonesetting are the most common in the northern and eastern regions. The average age of the Nigerian amputee is 33 years. Hospital mortality after amputation is 10.9%. The estimated prevalence of extremity amputation in Nigeria is 1.6 per 100,000. Peripheral artery disease is an uncommon indication for amputation in Nigeria while trauma, complication of traditional bonesetting, malignant tumours and diabetic gangrene are relatively much more common. The young male is frequently affected. [ABSTRACT FROM AUTHOR]
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- 2007
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11. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2) a randomised, placebo-controlled trial
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Olldashi, F., Kerçi, M., Zhurda, T., Ruçi, K., Banushi, A., Traverso, M. S., Jiménez, J., Balbi, J., Dellera, C., Svampa, S., Quintana, G., Piñero, G., Teves, J., Seppelt, I., Mountain, D., Balogh, Z., Zaman, M., Druwé, P., Rutsaert, R., Mazairac, G., Pascal, F., Yvette, Z., Chancellin, D., Okwen, P., Djokam-Liapoe, J., Jangwa, E., Mbuagbaw, L., Fointama, N., Pascal, N., Baillie, F., Jiang, J. -Y, Gao, G. -Y, Bao, Y. -H, Morales, C., Sierra, J., Naranjo, S., Correa, C., Gómez, C., Herrera, J., Caicedo, L., Rojas, A., Pastas, H., Miranda, H., Constaín, A., Perdomo, M., Muñoz, D., Duarte, Á, Vásquez, E., Ortiz, C., Ayala, B., Delgado, H., Benavides, G., Rosero, L., Mejía-Mantilla, J., Varela, A., Calle, M., Castillo, J., García, A., Ciro, J., Villa, C., Panesso, R., Flórez, L., Gallego, A., Puentes-Manosalva, F., Medina, L., Márquez, K., Romero, A. R., Hernández, R., Martínez, J., Gualteros, W., Urbina, Z., Velandia, J., Benítez, F., Trochez, A., Villarreal, A., Pabón, P., López, H., Quintero, L., Rubiano, A., Tamayo, J., Piñera, M., Navarro, Z., Rondón, D., Bujan, B., Palacios, L., Martínez, D., Hernández, Y., Fernández, Y., Casola, E., Delgado, R., Herrera, C., Arbolaéz, M., Domínguez, M., Iraola, M., Rojas, O., Enseñat, A., Pastrana, I., Rodríguez, D., La Campa, S. Á, Fortún, T., Larrea, M., Aragón, L., Madrazo, A., Svoboda, P., Izurieta, M., Daccach, A., Altamirano, M., Ortega, A., Cárdenas, B., González, L., Ochoa, M., Ortega, F., Quichimbo, F., Guiñanzaca, J., Zavala, I., Segura, S., Jerez, J., Acosta, D., Yánez, F., Camacho, R., Khamis, H., Shafei, H., Kheidr, A., Nasr, H., Mosaad, M., Rizk, S., El Sayed, H., Moati, T., Hokkam, E., Amin, M., Lowis, H., Fawzy, M., Bedir, N., Aldars, M., Rodríguez, V., Tobar, J., Alvarenga, J., Shalamberidze, B., Demuria, E., Rtveliashvili, N., Chutkerashvili, G., Dotiashvili, D., Gogichaishvili, T., Ingorokva, G., Kazaishvili, D., Melikidze, B., Iashvili, N., Tomadze, G., Chkhikvadze, M., Khurtsidze, L., Lomidze, Z., Dzagania, D., Kvachadze, N., Gotsadze, G., Kaloiani, V., Kajaia, N., Dakubo, J., Naaeder, S., Sowah, P., Yusuf, A., Ishak, A., Selasi-Sefenu, P., Sibiri, B., Sarpong-Peprah, S., Boro, T., Bopaiah, K., Shetty, K., Subbiah, R., Mulla, L., Doshi, A., Dewan, Y., Grewal, S., Tripathy, P., Mathew, J., Gupta, B., Lal, A., Choudhury, M., Gupta, S., Chug, A., Pamidimukkala, V., Jagannath, P., Maharaj, M., Vommi, R., Gudipati, N., Chhang, W. H., Patel, P., Suthar, N., Banker, D., Patel, J., Dharap, S., Kamble, R., Patkar, S., Lohiya, S., Saraf, R., Kumar, D., Parihar, S., Gupta, R., Mangual, R., Alagumuthu, Kooper, D., Mohapatra, C., David, S., Rajaleelan, W., Pangi, A., Saraf, V., Chikareddy, S., Mankar, S., Golhar, A., Sakhare, R., Wagh, N., Hazarika, D., Chaudhuri, P., Ketan, P., Purohit, G., Purohit, Y., Pandya, M., Kiran, S., Walia, S., Goyal, S., Attri, A., Sharma, R., Oberai, A., Oberai, M., Oberoi, S., Tripathi, G. K., Peettakkandy, V., Karuthillath, P., Vadakammuriyil, P., Pol, J., Pol, S., Saste, M., Raul, S., Tiwari, S., Nelly, N., Chidambaram, M., Kollengode, V., Thampan, S., Rajan, S., Raju, S., Babu, S. V., Sumathi, C., Chatterjee, P., Agarwal, A., Magar, H., Magar, M., Singh, M., Gupta, D., Haloi, K., Sagdeo, V., Giri, P., Verma, N., Jariwala, R., Goti, A., Prabhu-Gaonkar, A., Utagi, S., Joshi, M., Agrawal, R., Sharma, G., Saini, G., Tewari, V., Yadav, Y., Parihar, V., Venkataramana, N., Rao, S., Reddy, N., Chander, S. G., Hathila, V., Das, V., Agaja, K., Purohit, A., Lahari, A., Bhagchandani, R., Vidyasagar, B., Sachan, P. K., Das, T., Vyas, S., Bhattacharjee, S., Sancheti, P., Manoj, T., Moideen, M., Pansey, K., Chandrasekaran, V. P., Saikia, K., Tata, H., Vhora, S., Shah, A., Rangad, G., Rajasekaran, S., Shankarlal, S. T., Devadoss, S., Saleem, M., Pillay, H., Hazarika, Z., Deshmukh, P., Murugappan, S. P., Jaiswal, A., Vangani, D., Modha, P., Chonzik, C., Praveen, M., Sethurayar, V., Ipe, S., Shetty, N., Gupta, R. P., Jain, V., Shah, K., Dwikoryanto, M., Golden, N., Atmadjaya, K., Wiargitha, K., Sudiasa, K., Suwedagatha, G., Bal Afif, F., Budipramana, V., Tabrani, Lemuel, A., Chandra, S., Ama, F., Sherafatkazemzadeh, E., Moradi, E., Sheikhi, A., Ziaee, A., Fanaei, A., Hajinasrollah, E., Amini, A., Mohammad, B., Hadi, N., Perone, G., Peri, E., Volpi, A., Johnson, J., Abe, M., Mutiso, V., Okanga, B., Ojuka, D., Abdullah, B., Rahman, H., Noh, Y., Jamaluddin, S., Dawal, H., Roslani, A., Law, C. -W, Devashanti, P., Wahab, Y., Velaiutham, S., Dato, R., Loría, J., Montes, E., Gómez, E., Cazales, V., Bautista, P., Bautista, R., Ahumada, D., Hernández, E., Velásquez, G., Ortega, P., Lira, G., Estrada, F., Casasola, J., Olaomi, O., Abubakar, Y., Apollo, K., Badejo, O., Ihekire, O., Iribhogbe, P., Oludiran, O., Obeta, E., Okojie, C., Udefiagbon, E., Komolafe, E., Olaleye, P., Uzochukwu, T., Onakpoya, U., Dongo, A., Uhunmwagho, O., Eighemerio, E., Morgan, E., Thanni, L., Afolabi, A., Akinola, T., Ademola, A., Akute, O., Khalid, L., Abubakar, L., Aminu, M., Ogirima, M., Attansey, A., Michael, D., Aremu, O., Olugbenga, O., Ukpong, U., Salman, Y., Obianyo, N., Ani, C., Ezeadawi, R., Kehinde, O., Olaide, A., Jogo, A., Bitto, T., Anyanwu, S., Mbonu, O., Oludara, M., Somoye, M., Shehu, B., Ismail, N., Katchy, A., Ndoma-Egba, R., Grace-Inah, N., Songden, Z., Abdulraheem, A., Otu, A., Nottidge, T., Inyang, D., Idiapho, D., Giebel, H., Hassan, R., Adisa, A., Akinkuolie, A., Okam, K., Musa, A., Falope, I., Eze, J., Caballero, J., Azabache, W., Salirrosas, O., Soto, A., Torres, E., Ramírez, G., Malca, C., Velez, J., Yepez, R., Yupanqui, H., Lagos, P., Rodriguez, D., Flores, J., Moya, A., Barrionuevo, A., Gonzales-Portillo, M., Nunez, E., Eldawlatly, A., Al Naami, M., Delvi, B., Khalid, K., Alyafi, W., Djurovic, B., Ng, I., Yaghi, A., Laincz, A., Trenkler, S., Valky, J., Modiba, M., Legodi, P., Rangaka, T., Wallis, L., Muñoz, Á, Serrano, A., Misis, M., Rubi, M., La Torre, V., Ellawala, R., Wijeratna, S., Gunaratna, L., Wijayanayaka, C., Nungu, K., Billy Haonga, Mtapa, G., Yutthakasemsunt, S., Kittiwattanagul, W., Piyavechvirat, P., Impool, T., Thummaraj, S., Salaeh, R., Tangchitvittaya, S., Wattanakrai, K., Soonthornthum, C., Jiravongbunrod, T., Meephant, S., Subsompon, P., Pensuwan, P., Chamnongwit, W., Jerbi, Z., Cherif, A., Nash, M., Harris, T., Banerjee, J., Freij, R., Kendall, J., Moore, S., Townend, W., Cottingham, R., Becker, D., Lloyd, S., Burdett-Smith, P., Mirza, K., Webster, A., Brady, S., Grocutt, A., Thurston, J., Lecky, F., Goodacre, S., Mulla, Y., Sakala, D., and Chengo, C.
12. The spectrum of eye injuries in Sagamu, Nigeria.
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Ajibode HA, Thanni LO, Onabolu OO, Bodunde OT, and Otulana TO
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- Accidents, Adolescent, Adult, Aged, Child, Child, Preschool, Humans, Infant, Infant, Newborn, Middle Aged, Nigeria epidemiology, Prospective Studies, Surveys and Questionnaires, Young Adult, Eye Injuries epidemiology
- Abstract
Background: Eye injuries are major causes of visual morbidity and monocular blindness worldwide. The common causes of eye injuries needs to be well defined in each community so as to plan for prevention of high morbidity and blindness as part of blindness prevention programme., Objective: It is necessary to compare the trend in causes of ocular injuries in Ogun State after a similar study over 15 years before. The part played by road traffic accidents [RTA] compared to other causes is also to be analysed., Methodology: This prospective study was carried out between July 2004 and June 2005. All cases presenting to the Accident and Emergency Unit and Eye Clinic of Olabisi Onabanjo University Teaching Hospital, Sagamu, and the 2 private eye clinics in Sagamu town, presenting with any form of eye injuries during the study period were included. The biodata, cause and type of eye injury, time of injury, time of presentation and treatment offered were obtained using a questionnaire. The results were analysed with Epi-Info 2002., Results: One hundred and twelve patients were studied. Eighty-one [72.3%] of the victims were males; most of them, 36[33.0%] were students and 32 [29.4%] artisans. The common causes of eye injuries were RTA 35[31.3%], assault 22[19.6%], vegetative agents 18 [16.1%] and machine tools 11[9.8%]. Most patients presented either within 24 hours, 56[50.0%] or within a week, 34[30.4%] of injury, and mostly during the day 86[97.6%]. Most injuries were found in the anterior segment 95[84.8%] and most commonly, victims 65[58%] required only medications as treatment., Conclusion: Majority of eye injuries found in Sagamu are treatable and can be handled by an experienced non-ophthalmologist successfully and most are now accounted for by RTAs and assault which indicate some changes in common causes compared to previous studies in Nigeria.
- Published
- 2013
13. Radiographic pattern of skeletal trauma in children seen in a tertiary hospital in Sagamu, South West Nigeria.
- Author
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Olatunji AA and Thanni LO
- Subjects
- Accidental Falls, Accidents, Traffic, Adolescent, Birth Injuries diagnostic imaging, Bone and Bones injuries, Child, Child, Preschool, Female, Fractures, Bone etiology, Humans, Infant, Infant, Newborn, Male, Nigeria, Radiography, Retrospective Studies, Tertiary Care Centers, Bone and Bones diagnostic imaging, Fractures, Bone diagnostic imaging
- Abstract
Aims and Objectives: The study was aimed at identifying the pattern of skeletal trauma in the paediatric age group as it relates to the causes., Materials and Methods: A retrospective analysis of the records on the request cards, case notes, radiographs and reports (where available) of all children aged one day to 15 years who were referred to the radiology department of Olabisi Onabanjo University Teaching Hospital, Sagamu was carried out. Fractures were analysed with respect to sex, age, causes, type and location of fracture., Results: The analysis spanned a period of twenty-eight months during which a total of three hundred and twenty eight radiographs were analysed. The mean ages of male and female patients were 5.4±4.6 and 5.1±4.6 years, respectively, with a range of 0.2-15 years. Normal radiographs were found in 124 (37.80%) patients,53.1 (16.1%) had 55 fractures, and 39 (11.9%) had soft tissue swelling. Fractures were found most commonly in male children and in the age range 4-6 years. Fractures occur three times more in the upper limbs, and the bones most frequently affected are the humerus, radius, and the ulna in descending order. Most of the fractures were due to Road Traffic Injury (RTI) seen in 18.9%, falls seen in 18.9%, and birth trauma, which was responsible for 7.5%. The most frequently involved bone in fractures is the humerus followed by the femur bone. Skull fractures occur mostly in the parietal bone., Conclusions: Fractures are still mostly investigated with plain radiographs. Fractures are more frequent in male children and in the 4-6 year age range; it is seen more in the upper limb bones especially in the humerus. Skull fractures are relatively rare. Half of the fractures occur in the distal and mid portions of long bones. This study has also high lighted the importance of road traffic injury and falls as aetiological factors in fracture occurring in children. Effort should be made to ease deliveries in order to reduce the incidence of birth trauma.
- Published
- 2013
14. Patients' perception of quality of emergency care in a Nigerian teaching hospital: The influence of patient-provider interactions.
- Author
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Ariba AJ, Thanni LO, and Adebayo EO
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Attitude of Health Personnel, Cohort Studies, Female, Health Care Surveys, Hospitals, Teaching, Humans, Length of Stay, Male, Middle Aged, Nigeria, Socioeconomic Factors, Emergency Service, Hospital, Patient Satisfaction, Physician-Patient Relations
- Abstract
Background: Attention is rarely given to patients' opinions regarding the quality of care they received, which is an important feedback to healthcare providers, planners and policy makers., Aim: To assess how patients who survived life-threatening/emergency conditions percieved the quality of care they received., Method: This prospective study was carried out among adult patients who had received emergency care at the Accident & Emergency (A & E) unit of Olabisi Onabanjo University Teaching Hospital (OOUTH), Sagamu, between March and December 2004 using a semi-structured questionnaire., Results: There were 1129 respondents, 81 males and 48 females. Their mean age was 35.3 years. 62% were treated for surgical, and 37.2% for medical emergencies. The mean duration of stay at A & E was 2.4 days. Although 91% of the respondents regarded available equipments as very adequate, 38.8% perceived the overall quality of care as sub-optimal. Many of the patients were displeased with their interactions with care providers. They longed for urgent improvement in waiting time, speed of issuing drugs, imterpersonal relationship with health workers and attending to emotional distress of emergency victims. They also wished to have free treatment during emergencies, Conclusion: Majority of the patients who received care in A & E of this tertiary hospital perceived the quality of care received as satisfactory. However, a substantial proportion regarded the quality of care as sub-optimal. Although most thought equipments were adequate, many of them expressed displeasure with their interactions with care providers. To improve patient's satisfaction with emergency care, greater emphasis needs to be placed on enhancing the interpersonal relationships between health workers and patients than is currently done.
- Published
- 2007
15. Iatrogenic arterial injury and foot gangrene. A case report.
- Author
-
Thanni LO
- Subjects
- Child, Female, Gangrene etiology, Humans, Amputation, Surgical, Elective Surgical Procedures adverse effects, Foot surgery, Gangrene surgery, Iatrogenic Disease, Ischemia etiology, Popliteal Artery injuries
- Abstract
Background: Elective orthopaedic operations on the knee is rarely complicated by arterial injury., Report: A case report is presented of a 10 year old girl that developed gangrene of the foot following an elective orthopaedic operation on the proximal tibial metaphysis. A transfixion wire that breached the posterior tibial cortex was most probably responsible for popliteal artery injury that resulted in ischaemia and gangrene. The patient had an amputation of all the toes in the affected limb and recovered satisfactory limb function., Conclusion: In operations on the proximal tibial metaphysis, implants (screws, pins, wires) should not be allowed to perforate the posterior cortex. When this occurs inadvertently, they should be readjusted as soon as radiographs confirm this, to avoid injury to the popliteal artery.
- Published
- 2007
16. Short-term antibiotic prophylaxis in implant surgery: a comparison of three antibiotics.
- Author
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Yinusa W, Onche II, and Thanni LO
- Subjects
- Adolescent, Adult, Aged, Cross Infection prevention & control, Drug Administration Schedule, Female, Gram-Negative Bacterial Infections prevention & control, Humans, Male, Middle Aged, Treatment Outcome, Anti-Bacterial Agents administration & dosage, Antibiotic Prophylaxis methods, Ceftriaxone administration & dosage, Cefuroxime administration & dosage, Ciprofloxacin administration & dosage, Prosthesis-Related Infections prevention & control
- Abstract
Objective: To investigate the efficacy, tolerability and cost effectiveness of three antibiotics in a short-term antibiotic regimen in patients undergoing elective implant surgery., Patients and Methods: 89 patients who underwent 101 implantation procedures were enrolled during a period of five years and randomly divided into three groups to receive: (a) Rocephin (Ceftriaxone) 1g intravenously at induction and 1g 12 hours later (Group 1). (b) Zinacef (Cefuroxime) 1.5 g intravenously at induction and 750 mg six hourly for 12 hours (Group 2). Ciprotab (ciprofloxacine) 400mg intravenously at induction and 200mg six hourly for 12 hours (group 3)., Results: The patients in the three groups were comparable regarding age, gender, pre-operative length of hospitalization and duration of surgery. The overall surgical site infection rate was 6.9% (7/101) with gram-negative organisms being the most common causative organisms (71.4%). The infection rates of 6.3% in group 1,7.3% in group 2 and 7.1% in group 3 show no statistical significance (P>0.05). The cost benefit ratio for the three drugs showed that treatment with Ciprotab was cheaper than that with Rocephin or Zinacef. Severe complications warranting discontinuation of therapy did not occur in any of the three groups of patients., Conclusion: While we can safely conclude that all the drugs have similar efficacy and safely in preventing post-operative wound complications, it appears that Ciprotab is most cost-effective. We recommend that a larger study be undertaken to confirm the predominance of gram-negative organisms in implant surgery.
- Published
- 2007
17. Bacterial osteomyelitis in major sickling haemoglobinopathies: geographic difference in pathogen prevalence.
- Author
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Thanni LO
- Subjects
- Africa South of the Sahara, Europe, Humans, Middle East, Osteomyelitis complications, Osteomyelitis etiology, United States, Hemoglobin, Sickle, Hemoglobinopathies complications, Osteomyelitis microbiology, Salmonella pathogenicity, Staphylococcus aureus pathogenicity
- Abstract
Background: Controversy exists about the bacterial pathogen that is most often associated with osteomyelitis in major sickling haemoglobinopathies, that is, HbSS, HbSC, and HbSthalassemia., Objective: To determine the existence of regional or continental differences in the prevalence of bacterial pathogens associated with osteomyelitis in sickling haemoglobinopathies., Method: A meta-analysis is done of 11 year hospital data set and published studies in African Journals Online (Ajol) and Pubmed electronic databases on the subject., Results: Fifteen studies including two hundred and eighty one bacterial pathogens from SubSaharan Africa, United States, Europe and the Middle East were analysed. There were 129 (45.9%) salmonellae, 82 (29.2%) Staphylococcus aureus, 55 (19.6%) other Gram negative bacilli (GNB) and 15 (5.3%) other Gram positive cocci (GPC). There were 117 isolates in the studies from Africa out of which salmonellae accounted for 21.4%, S. aureus 38.5%, other GNB 34.2% and other GPC 6%. In contrast, out of 110 isolates in the studies from the USA, salmonellae were 70%, S. aureus 16.4%, other GNB 9.1% and other GPC 4.5%. Salmonellae and S. aureus accounted for 37.9% and 62.1%; 64% and 4.9% in isolates from the Middle East and Europe respectively., Conclusions: Salmonellae are the most common bacterial pathogens of osteomyelitis in major sickling haemoglobinopathies in the USA and Europe whereas Staphylococcus aureus is the most common pathogen in SubSaharan Africa and the Middle East. The worldwide prevalence of salmonella may be reducing while that of S. aureus may be increasing. Possible reasons for this observation are suggested.
- Published
- 2006
- Full Text
- View/download PDF
18. Trauma at a Nigerian teaching hospital: pattern and docu-mentation of presentation.
- Author
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Thanni LO and Kehinde OA
- Subjects
- Accidents, Traffic statistics & numerical data, Adolescent, Adult, Age Distribution, Aged, Aged, 80 and over, Cause of Death, Child, Child, Preschool, Cohort Studies, Developing Countries, Documentation trends, Emergency Service, Hospital statistics & numerical data, Female, Fractures, Bone diagnosis, Fractures, Bone epidemiology, Hospitals, Teaching, Humans, Incidence, Infant, Injury Severity Score, Lacerations diagnosis, Lacerations epidemiology, Male, Medical Records, Middle Aged, Multiple Trauma diagnosis, Multiple Trauma epidemiology, Nigeria epidemiology, Retrospective Studies, Sex Distribution, Survival Rate, Young Adult, Documentation standards, Hospital Mortality trends, Wounds and Injuries diagnosis, Wounds and Injuries epidemiology
- Abstract
Background and Objectives: This study is aimed at identifying the characteristics of injuries and determining the efficiency of documentation of patients' records in a tertiary hospital where there is no trauma registry., Patients and Methods: A retrospective case record analysis was conducted of injured patients seen at the Accident and Emergency unit over a 12 month period from January to December 2003., Results: A total of 1078 records of injured patients that attended the A&E were analysed. Their mean age was 31 years (range 3 months to 85 years). Laceration (n = 408) and fractures (n = 266) representing 62.5% of injuries were seen. Injuries to the lower limb occurred in 239 patients, multiple anatomical sites 224, head 224, upper limb 203, the neck 20, and the abdomen 11 patients. Trauma was due to road traffic accident in 977 patients, fall in 39, assault in 14 while burns and firearm injuries occurred in 5 and 7 patients respectively. The mean injury severity score (ISS) was 4. Severe injuries, ISS > 15 occurred in 54 patients with mean ISS of 21, and resulted from RTA in 92.6% of cases. Mortality from severe injuries occurred in 31.5% of cases while overall mortality was 2%. Most deaths were associated with multiple injuries (60.9%) and head injury (30.4%). Incomplete documentation of accident and injury data occurred frequently, from 2% of some data to 100% of others., Conclusions: Lacerations and fractures were the most common injuries. Mortality is due usually to head and multiple injuries. Research into appropriate strategies for prevention of injuries, especially RTA, is required but this must start with the establishment of institutional and regional trauma registries for complete documentation of relevant data.
- Published
- 2006
- Full Text
- View/download PDF
19. Re: double blind clinical trial comparing the safety and efficacy of nimesulide. (100mg) and diclofenac in osteoarthrosis of the hip and knee joints.
- Author
-
Thanni LO
- Subjects
- Adult, Aged, Aged, 80 and over, Anti-Inflammatory Agents, Non-Steroidal adverse effects, Diclofenac adverse effects, Double-Blind Method, Female, Humans, Male, Middle Aged, Pain etiology, Randomized Controlled Trials as Topic, Sulfonamides adverse effects, Treatment Outcome, Anti-Inflammatory Agents, Non-Steroidal therapeutic use, Diclofenac therapeutic use, Osteoarthritis, Hip physiopathology, Osteoarthritis, Knee physiopathology, Pain drug therapy, Sulfonamides therapeutic use
- Published
- 2006
20. A retrospective audit of paediatric surgical admission in a sub-urban tertiary hospital.
- Author
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Thanni LO, Shonubi AM, and Akiode O
- Subjects
- Adolescent, Bed Occupancy statistics & numerical data, Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Medical Audit, Nigeria, Retrospective Studies, Hospitals, Teaching statistics & numerical data, Length of Stay, Patient Admission statistics & numerical data, Surgery Department, Hospital statistics & numerical data, Utilization Review
- Abstract
Background: Data on utilization of paediatric surgical services and the burden of paediatric surgical diseases in the West African subregion is scarce., Methodology: This retrospective study describes paediatric surgical admissions in a Nigerian teaching hospital between January 1998 and December 2002., Results: Two hundred and eighty three children up to 15 years of age with surgical disorders were studied. Their mean age (+/- SD) was 5.8 +/- 4 years for males and 6.9 +/- 4 years for females. Length of stay (LOS) ranged from 1 to 127 days (mean 17 days). Turnover interval declined from 22.1 to 6.4 days while percentage bed occupancy and patients per bed per year averaged 70% and 17.4 respectively between January 2000 and December 2002. The highest mean LOS was due to malignant neoplasm (38 +/- 12 days), trauma (22 +/- 25) and surgical infection (21 +/- 22 days) while the shortest mean LOS was due to foreign body (6 +/- 4 days). The most common admitting diagnoses were trauma (36.7%), congenital anomalies (27.9%) and surgical infections (22.6%). Foreign body (2.1 %), benign tumours (0.7%) and malignant neoplasms (0.7%) were uncommon. Overall mortality was 0.4%., Conclusions: Childhood injuries, congenital anomalies and infections are important paediatric health problems.
- Published
- 2005
- Full Text
- View/download PDF
21. Evaluation of guidelines for skull radiography in head injury.
- Author
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Thanni LO
- Subjects
- Adolescent, Adult, Aged, Child, Child, Preschool, Craniocerebral Trauma etiology, Female, Guideline Adherence, Humans, Infant, Male, Middle Aged, Nigeria, Radiography, Craniocerebral Trauma diagnostic imaging, Skull diagnostic imaging, Skull Fractures diagnostic imaging
- Abstract
The benefits of utilisation of guidelines for radiographic skull examination of head injured patients were studied in one hundred and eleven patients. The causes of head injury were road traffic accidents (RTA) 87.4%, fall and assault 4.5% each, collapsed wall 1.8%, gunshot injury and industrial accident 0.9% each. RTA resulted predominantly from burst tyre 34%, vehicle pedestrian accidents 23.7% and vehicle collision 18.6%. Compliance with the use of the guidelines was 48%. Radiographic skull examination was carried out in 22 patients (20% of study population) and the positive yield for skull fracture was 32% (7/22 of all radiographs). At discharge, 14 of those who had radiographic examination (n=20) recovered without neurological complications while 39 among those not examined (n=58) similarly recovered, p=0.96. Among those who had skull radiography, neurological deficit occurred in 6 that had skull fractures (n=7) and in 5 of those without skull fractures (n=13), p=0.07. It was concluded that radiographic skull examination based on selective guidelines increases the yield of skull fractures and reduces unnecessary examinations, thereby saving costs. Skull radiography may not be predictive of neurological outcome of treatment. Cranial computed tomography (CT) should be obtained if available and clinically indicated.
- Published
- 2003
22. Factors influencing patronage of traditional bone setters.
- Author
-
Thanni LO
- Subjects
- Adolescent, Adult, Age Distribution, Aged, Educational Status, Female, Fractures, Bone complications, Health Knowledge, Attitudes, Practice, Humans, Male, Middle Aged, Nigeria, Surveys and Questionnaires, Fractures, Bone psychology, Fractures, Bone therapy, Medicine, African Traditional, Patient Acceptance of Health Care psychology, Patient Acceptance of Health Care statistics & numerical data
- Abstract
In clinical orthopaedic practice, many patients are seen presenting with complications after being treated by traditional bone setters (TBS). These complications do not seem to deter other patients from patronising the TBS rather than modern orthopaedic service (MOS). Basic beliefs about TBS in particular and traditional healers (TH) in general are likely to be responsible for their continuing popularity. One hundred and eighty adults and adolescents were surveyed by means of interviewer administered questionnaires at a popular motor park, traditional and modern health facilities. While 37% (n = 67) of the respondents believe that TBS are indispensable (cannot do without), 32.8% (n = 65) believe they are desirable (can do without though useful) and 11% (n = 20) thought they are nuisances and fraudsters. Forty three per cent of them felt that TBS are competent or very competent, 24% adjudged their practice satisfactory (good but with some deficiencies) and 23% believe they are either incompetent or very incompetent. Education did not seem to influence these beliefs as the expressed opinion on the indispensability/desirability of TBS by those who had no formal education was similar to that of those who had primary education, p > 0.5, and College/University education, p) 0.1. The services of the TBS were thought to be cheaper (n = 103) than MOS (n = 36) although more (n = 120) believe that doctors explain the causes of injuries and illness rather than TBS (n = 35). The community opinion of TBS, irrespective of educational status, is probably predominantly positive in addition to their services being thought to be cheaper than modern orthopaedic service, hence their continued relevance in the treatment of musculo skeletal injuries and diseases.
- Published
- 2000
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