Search

Your search keyword '"Thangamuthu, Karthik"' showing total 14 results
Start Over Author "Thangamuthu, Karthik"
14 results on '"Thangamuthu, Karthik"'

2. THU603 Bone Fragility In Mild Autonomous Cortisol Secretion: A Cross-Sectional Cohort Study

Author

Zhang, Catherine D, primary, Singh, Sumitabh, additional, Saini, Jasmine, additional, Suresh, Malavika, additional, Thangamuthu, Karthik, additional, Nathani, Rohit, additional, Ebbehøj, Andreas Ladefoged, additional, Fell, Vanessa, additional, Achenbach, Sara J, additional, Atkinson, Elizabeth J, additional, Khosla, Sundeep, additional, and Bancos, Irina, additional

Published
2023
Full Text
View/download PDF

3. THU606 Cognitive Impairment In Patients With Mild Autonomous Cortisol Secretion: A Cross-sectional Study

Author

Saini, Jasmine, primary, Nathani, Rohit, additional, Singh, Sumitabh, additional, Thangamuthu, Karthik, additional, Suresh, Malavika, additional, Zhang, Catherine, additional, Ebbehøj, Andreas Ladefoged, additional, Thomas, Melinda, additional, Fell, Vanessa, additional, Atkinson, Elizabeth, additional, Achenbach, Sara, additional, Stricker, Nikki, additional, and Bancos, Irina, additional

Published
2023
Full Text
View/download PDF

5. High Prevalence of Frailty in Patients with Adrenal Adenomas and Adrenocortical Hormone Excess – a cross-sectional multi-centre study with prospective enrolment.

Author

Dogra, Prerna, primary, Šambula, Lana, additional, Saini, Jasmine, additional, Thangamuthu, Karthik, additional, Athimulam, Shobana, additional, Delivanis, Danae A, additional, Baikousi, Dimitra A, additional, Nathani, Rohit, additional, Zhang, Catherine D, additional, Genere, Natalia, additional, Salman, Zara, additional, Turcu, Adina F, additional, Ambroziak, Urszula, additional, Garcia, Raul Gregg, additional, Achenbach, Sara J, additional, Atkinson, Elizabeth J, additional, Singh, Sumitabh, additional, LeBrasseur, Nathan K, additional, Kastelan, Darko, additional, and Bancos, Irina, additional

Published
2023
Full Text
View/download PDF

6. Glucocorticoid withdrawal syndrome following surgical remission of endogenous hypercortisolism: a longitudinal observational study

Author

Zhang, Catherine D, primary, Li, Dingfeng, additional, Singh, Sumitabh, additional, Suresh, Malavika, additional, Thangamuthu, Karthik, additional, Nathani, Rohit, additional, Achenbach, Sara J, additional, Atkinson, Elizabeth J, additional, Van Gompel, Jamie J, additional, Young, William F, additional, and Bancos, Irina, additional

Published
2023
Full Text
View/download PDF

7. Determinants of muscle function and health-related quality of life in patients with endogenous hypercortisolism: a cross-sectional study

Author

Li, Dingfeng, primary, Zhang, Catherine D, additional, Saini, Jasmine, additional, Singh, Sumitabh, additional, Nathani, Rohit, additional, Thangamuthu, Karthik, additional, Suresh, Malavika, additional, Atkinson, Elizabeth J, additional, Achenbach, Sara J, additional, Van Gompel, Jamie, additional, Young, William F, additional, and Bancos, Irina, additional

Published
2023
Full Text
View/download PDF

13. LBSAT141 Bone Health In Patients With Adrenal Disorders

Author

Dogra, Prerna, primary, Šambula, Lana, additional, Zhang, Catherine D, additional, Thangamuthu, Karthik, additional, Nathani, Rohit, additional, Kastelan, Darko, additional, Ambroziak, Urszula, additional, Genere, Natalia, additional, Delivanis, Danae, additional, and Bancos, Irina, additional

Published
2022
Full Text
View/download PDF

14. Determinants of muscle function and health-related quality of life in patients with endogenous hypercortisolism: a cross-sectional study.

Author

Dingfeng Li, Zhang, Catherine D., Saini, Jasmine, Singh, Sumitabh, Nathani, Rohit, Thangamuthu, Karthik, Suresh, Malavika, Atkinson, Elizabeth J., Achenbach, Sara J., Van Gompel, Jamie, Young, William F., and Bancos, Irina

Subjects
MUSCLE strength, QUALITY of life, CUSHING'S syndrome
Abstract

Objective: Prospective data on determinants of muscle strength impairment and quality of life in patients with various subtypes and severity of endogenous hypercortisolism are lacking. Design: Single-center cross-sectional study, 2019 to 2022. Methods: Patients with Cushing syndrome (CS) and mild autonomous cortisol secretion (MACS) were assessed with clinical and biochemical severity scores, muscle function (nondominant hand grip strength and sit-to-stand test), and quality of life (Short Form-36 [SF36] and CushingQoL). Referent subjects were recruited from the local population undergoing abdominal imaging for reasons other than suspected adrenal disorder. Results: Of 164 patients, 81 (49%) had MACS, 14 (9%) had adrenal CS, 60 (37%) had pituitary CS, and 9 (5%) had ectopic CS. Median age was 53 years (interquartile range: 42-63 years), and 126 (77%) were women. The SF36 mental component score was similarly low in patients with MACS vs CS, but physical component score was lower in CS when compared to MACS (mean of 34.0 vs 40.5, P = .001). Compared to MACS, patients with CS had lower scores on the standardized CushingQoL (mean of 47.1 vs 34.2, P < .001). Compared to referent subjects, patients with MACS demonstrated reduced muscle strength, similar to patients with CS (mean sit to stand Z-score of -0.47 vs -0.54, P = .822). Clinical severity (r = -0.22, P = .004) but not biochemical severity was associated with sit-to-stand test performance. Conclusions: Both patients with overt CS and MACS demonstrate reduced muscle strength and low quality of life. The clinical severity score utilized is associated with both physical and psychosocial components of CushingQoL and with the physical component of SF36. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results