1. Treatment and pregnancy outcomes of pregnant women exposed to second-line anti-tuberculosis drugs in South Africa
- Author
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Idah Mokhele, Nelly Jinga, Rebecca Berhanu, Thandi Dlamini, Lawrence Long, and Denise Evans
- Subjects
Multi-drug-resistant tuberculosis ,Rifampicin resistance ,South Africa ,Pregnancy ,HIV ,Second-line anti-TB treatment ,Gynecology and obstetrics ,RG1-991 - Abstract
Abstract Background Multi-drug resistant and rifampicin-resistant tuberculosis (MDR/RR-TB) in pregnant women is a cause for concern globally; few data have described the safety of second-line anti-TB medications during pregnancy. We aim to describe TB treatment and pregnancy outcomes among pregnant women receiving second-line anti-tuberculosis treatment for MDR/RR-TB in Johannesburg, South Africa. Methods We conducted a retrospective record review of pregnant women (≥ 18 years) who received treatment for MDR/RR-TB between 01/2010–08/2016 at three outpatient treatment sites in Johannesburg, South Africa. Demographic, treatment and pregnancy outcome data were collected from available medical records. Preterm birth (
- Published
- 2021
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