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3. Posttransplantation late complications increase over time for patients with SCID: A Primary Immune Deficiency Treatment Consortium (PIDTC) landmark study

Author

Eissa, Hesham, Thakar, Monica S., Shah, Ami J., Logan, Brent R., Griffith, Linda M., Dong, Huaying, Parrott, Roberta E., O’Reilly, Richard J., Dara, Jasmeen, Kapoor, Neena, Forbes Satter, Lisa, Chandra, Sharat, Kapadia, Malika, Chandrakasan, Shanmuganathan, Knutsen, Alan, Jyonouchi, Soma C., Molinari, Lyndsay, Rayes, Ahmad, Ebens, Christen L., Teira, Pierre, Dávila Saldaña, Blachy J., Burroughs, Lauri M., Chaudhury, Sonali, Chellapandian, Deepak, Gillio, Alfred P., Goldman, Fredrick, Malech, Harry L., DeSantes, Kenneth, Cuvelier, Geoff D.E., Rozmus, Jacob, Quinones, Ralph, Yu, Lolie C., Broglie, Larisa, Aquino, Victor, Shereck, Evan, Moore, Theodore B., Vander Lugt, Mark T., Mousallem, Talal I., Oved, Joeseph H., Dorsey, Morna, Abdel-Azim, Hisham, Martinez, Caridad, Bleesing, Jacob H., Prockop, Susan, Kohn, Donald B., Bednarski, Jeffrey J., Leiding, Jennifer, Marsh, Rebecca A., Torgerson, Troy, Notarangelo, Luigi D., Pai, Sung-Yun, Pulsipher, Michael A., Puck, Jennifer M., Dvorak, Christopher C., Haddad, Elie, Buckley, Rebecca H., Cowan, Morton J., and Heimall, Jennifer

Published
2024
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4. Infections in Infants with SCID: Isolation, Infection Screening, and Prophylaxis in PIDTC Centers.

Author

Dorsey, Morna J, Wright, Nicola AM, Chaimowitz, Natalia S, Dávila Saldaña, Blachy J, Miller, Holly, Keller, Michael D, Thakar, Monica S, Shah, Ami J, Abu-Arja, Rolla, Andolina, Jeffrey, Aquino, Victor, Barnum, JL, Bednarski, Jeffrey J, Bhatia, Monica, Bonilla, Francisco A, Butte, Manish J, Bunin, Nancy J, Chandra, Sharat, Chaudhury, Sonali, Chen, Karin, Chong, Hey, Cuvelier, Geoffrey DE, Dalal, Jignesh, DeFelice, Magee L, DeSantes, Kenneth B, Forbes, Lisa R, Gillio, Alfred, Goldman, Fred, Joshi, Avni Y, Kapoor, Neena, Knutsen, Alan P, Kobrynski, Lisa, Lieberman, Jay A, Leiding, Jennifer W, Oshrine, Benjamin, Patel, Kiran P, Prockop, Susan, Quigg, Troy C, Quinones, Ralph, Schultz, Kirk R, Seroogy, Christine, Shyr, David, Siegel, Subhadra, Smith, Angela R, Torgerson, Troy R, Vander Lugt, Mark T, Yu, Lolie C, Cowan, Morton J, Buckley, Rebecca H, Dvorak, Christopher C, Griffith, Linda M, Haddad, Elie, Kohn, Donald B, Logan, Brent, Notarangelo, Luigi D, Pai, Sung-Yun, Puck, Jennifer, Pulsipher, Michael A, and Heimall, Jennifer

Subjects
Humans, Severe Combined Immunodeficiency, Disease Susceptibility, Neonatal Screening, Prognosis, Antibiotic Prophylaxis, Hematopoietic Stem Cell Transplantation, Age of Onset, Infection Control, Infant, Infant, Newborn, Disease Management, Female, Male, Public Health Surveillance, Time-to-Treatment, Surveys and Questionnaires, Clinical Decision-Making, Infections, hematopoietic stem cell transplant, newborn screening, primary immunodeficiency, prophylaxis, severe combined immunodeficiency, Stem Cell Research, Perinatal Period - Conditions Originating in Perinatal Period, Pediatric, Prevention, Regenerative Medicine, Transplantation, Infant Mortality, Health Services, Clinical Research, Infection, Immunology
Abstract

PurposeThe Primary Immune Deficiency Treatment Consortium (PIDTC) enrolled children with severe combined immunodeficiency (SCID) in a prospective natural history study of hematopoietic stem cell transplant (HSCT) outcomes over the last decade. Despite newborn screening (NBS) for SCID, infections occurred prior to HSCT. This study's objectives were to define the types and timing of infection prior to HSCT in patients diagnosed via NBS or by family history (FH) and to understand the breadth of strategies employed at PIDTC centers for infection prevention.MethodsWe analyzed retrospective data on infections and pre-transplant management in patients with SCID diagnosed by NBS and/or FH and treated with HSCT between 2010 and 2014. PIDTC centers were surveyed in 2018 to understand their practices and protocols for pre-HSCT management.ResultsInfections were more common in patients diagnosed via NBS (55%) versus those diagnosed via FH (19%) (p = 0.012). Outpatient versus inpatient management did not impact infections (47% vs 35%, respectively; p = 0.423). There was no consensus among PIDTC survey respondents as to the best setting (inpatient vs outpatient) for pre-HSCT management. While isolation practices varied, immunoglobulin replacement and antimicrobial prophylaxis were more uniformly implemented.ConclusionInfants with SCID diagnosed due to FH had lower rates of infection and proceeded to HSCT more quickly than did those diagnosed via NBS. Pre-HSCT management practices were highly variable between centers, although uses of prophylaxis and immunoglobulin support were more consistent. This study demonstrates a critical need for development of evidence-based guidelines for the pre-HSCT management of infants with SCID following an abnormal NBS.Trial registrationNCT01186913.

Published
2021

5. Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from the Primary Immune Deficiency Treatment Consortium

Author

Thakar, Monica S, Logan, Brent R, Puck, Jennifer M, Dunn, Elizabeth A, Buckley, Rebecca H, Cowan, Morton J, O'Reilly, Richard J, Kapoor, Neena, Satter, Lisa Forbes, Pai, Sung-Yun, Heimall, Jennifer, Chandra, Sharat, Ebens, Christen L, Chellapandian, Deepak, Williams, Olatundun, Burroughs, Lauri M, Saldana, Blachy Davila, Rayes, Ahmad, Madden, Lisa M, Chandrakasan, Shanmuganathan, Bednarski, Jeffrey J, II, DeSantes, Kenneth B, Cuvelier, Geoffrey D E, Teira, Pierre, Gillio, Alfred P, Eissa, Hesham, Knutsen, Alan P, Goldman, Frederick D, Aquino, Victor M, Shereck, Evan B, Moore, Theodore B, Caywood, Emi H, Lugt, Mark T Vander, Rozmus, Jacob, Broglie, Larisa, Yu, Lolie C, Shah, Ami J, Andolina, Jeffrey R, Liu, Xuerong, Parrott, Roberta E, Dara, Jasmeen, Prockop, Susan, Martinez, Caridad A, Kapadia, Malika, Jyonouchi, Soma C, Sullivan, Kathleen E, Bleesing, Jack J, Chaudhury, Sonali, Petrovic, Aleksandra, Keller, Michael D, Quigg, Troy C, Parikh, Suhag, Shenoy, Shalini, Seroogy, Christine, Rubin, Tamar, Decaluwe, Hélène, Routes, John M, Torgerson, Troy R, Leiding, Jennifer W, Pulsipher, Michael A, Kohn, Donald B, Griffith, Linda M, Haddad, Elie, Dvorak, Christopher C, and Notarangelo, Luigi D

Published
2023
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6. The diagnosis of severe combined immunodeficiency: Implementation of the PIDTC 2022 Definitions

Author

Dvorak, Christopher C., Haddad, Elie, Heimall, Jennifer, Dunn, Elizabeth, Cowan, Morton J., Pai, Sung-Yun, Kapoor, Neena, Satter, Lisa Forbes, Buckley, Rebecca H., O’Reilly, Richard J., Chandra, Sharat, Bednarski, Jeffrey J., Williams, Olatundun, Rayes, Ahmad, Moore, Theodore B., Ebens, Christen L., Davila Saldana, Blachy J., Petrovic, Aleksandra, Chellapandian, Deepak, Cuvelier, Geoffrey D.E., Vander Lugt, Mark T., Caywood, Emi H., Chandrakasan, Shanmuganathan, Eissa, Hesham, Goldman, Frederick D., Shereck, Evan, Aquino, Victor M., Desantes, Kenneth B., Madden, Lisa M., Miller, Holly K., Yu, Lolie, Broglie, Larisa, Gillio, Alfred, Shah, Ami J., Knutsen, Alan P., Andolina, Jeffrey P., Joshi, Avni Y., Szabolcs, Paul, Kapadia, Malika, Martinez, Caridad A., Parrot, Roberta E., Sullivan, Kathleen E., Prockop, Susan E., Abraham, Roshini S., Thakar, Monica S., Leiding, Jennifer W., Kohn, Donald B., Pulsipher, Michael A., Griffith, Linda M., Notarangelo, Luigi D., and Puck, Jennifer M.

Published
2023
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7. Chronic Granulomatous Disease-Associated IBD Resolves and Does Not Adversely Impact Survival Following Allogeneic HCT.

Author

Marsh, Rebecca A, Leiding, Jennifer W, Logan, Brent R, Griffith, Linda M, Arnold, Danielle E, Haddad, Elie, Falcone, E Liana, Yin, Ziyan, Patel, Kadam, Arbuckle, Erin, Bleesing, Jack J, Sullivan, Kathleen E, Heimall, Jennifer, Burroughs, Lauri M, Skoda-Smith, Suzanne, Chandrakasan, Shanmuganathan, Yu, Lolie C, Oshrine, Benjamin R, Cuvelier, Geoffrey DE, Thakar, Monica S, Chen, Karin, Teira, Pierre, Shenoy, Shalini, Phelan, Rachel, Forbes, Lisa R, Chellapandian, Deepak, Dávila Saldaña, Blachy J, Shah, Ami J, Weinacht, Katja G, Joshi, Avni, Boulad, Farid, Quigg, Troy C, Dvorak, Christopher C, Grossman, Debi, Torgerson, Troy, Graham, Pamela, Prasad, Vinod, Knutsen, Alan, Chong, Hey, Miller, Holly, de la Morena, M Teresa, DeSantes, Kenneth, Cowan, Morton J, Notarangelo, Luigi D, Kohn, Donald B, Stenger, Elizabeth, Pai, Sung-Yun, Routes, John M, Puck, Jennifer M, Kapoor, Neena, Pulsipher, Michael A, Malech, Harry L, Parikh, Suhag, Kang, Elizabeth M, and submitted on behalf of the Primary Immune Deficiency Treatment Consortium

Subjects
submitted on behalf of the Primary Immune Deficiency Treatment Consortium, Neutrophils, Transplantation Chimera, Humans, Inflammatory Bowel Diseases, Granulomatous Disease, Chronic, Graft vs Host Disease, Leukocyte Count, Prognosis, Treatment Outcome, Hematopoietic Stem Cell Transplantation, Transplantation, Homologous, Severity of Illness Index, Incidence, Retrospective Studies, Adolescent, Adult, Child, Child, Preschool, Infant, Female, Male, Young Adult, Allogeneic hematopoietic cell transplantation, allogeneic bone marrow transplantation, allogeneic hematopoietic stem cell transplantation, chronic granulomatous disease, inflammatory bowel disease, primary immunodeficiency, Autoimmune Disease, Inflammatory Bowel Disease, Digestive Diseases, Rare Diseases, Clinical Research, Transplantation, Oral and gastrointestinal, Immunology
Abstract

IntroductionInflammatory bowel disease (IBD) affects approximately 1/3 of patients with chronic granulomatous disease (CGD). Comprehensive investigation of the effect of allogeneic hematopoietic cell transplantation (HCT) on CGD IBD and the impact of IBD on transplant outcomes is lacking.MethodsWe collected data retrospectively from 145 patients with CGD who had received allogeneic HCT at 26 Primary Immune Deficiency Treatment Consortium (PIDTC) centers between January 1, 2005 and June 30, 2016.ResultsForty-nine CGD patients with IBD and 96 patients without IBD underwent allogeneic HCT. Eighty-nine percent of patients with IBD and 93% of patients without IBD engrafted (p = 0.476). Upper gastrointestinal acute GVHD occurred in 8.5% of patients with IBD and 3.5% of patients without IBD (p = 0.246). Lower gastrointestinal acute GVHD occurred in 10.6% of patients with IBD and 11.8% of patients without IBD (p = 0.845). The cumulative incidence of acute GVHD grades II-IV was 30% (CI 17-43%) in patients with IBD and 20% (CI 12-29%) in patients without IBD (p = 0.09). Five-year overall survival was equivalent for patients with and without IBD: 80% [CI 66-89%] and 83% [CI 72-90%], respectively (p = 0.689). All 33 surviving evaluable patients with a history of IBD experienced resolution of IBD by 2 years following allogeneic HCT.ConclusionsIn this cohort, allogeneic HCT was curative for CGD-associated IBD. IBD should not contraindicate HCT, as it does not lead to an increased risk of mortality. This study is registered at clinicaltrials.gov NCT02082353.

Published
2019

8. Outcomes following treatment for ADA-deficient severe combined immunodeficiency: a report from the PIDTC

Author

Cuvelier, Geoffrey D.E., Logan, Brent R., Prockop, Susan E., Buckley, Rebecca H., Kuo, Caroline Y., Griffith, Linda M., Liu, Xuerong, Yip, Alison, Hershfield, Michael S., Ayoub, Paul G., Moore, Theodore B., Dorsey, Morna J., O'Reilly, Richard J., Kapoor, Neena, Pai, Sung-Yun, Kapadia, Malika, Ebens, Christen L., Forbes Satter, Lisa R., Burroughs, Lauri M., Petrovic, Aleksandra, Chellapandian, Deepak, Heimall, Jennifer, Shyr, David C., Rayes, Ahmad, Bednarski, Jeffrey J., Chandra, Sharat, Chandrakasan, Shanmuganathan, Gillio, Alfred P., Madden, Lisa, Quigg, Troy C., Caywood, Emi H., Dávila Saldaña, Blachy J., DeSantes, Kenneth, Eissa, Hesham, Goldman, Frederick D., Rozmus, Jacob, Shah, Ami J., Vander Lugt, Mark T., Thakar, Monica S., Parrott, Roberta E., Martinez, Caridad, Leiding, Jennifer W., Torgerson, Troy R., Pulsipher, Michael A., Notarangelo, Luigi D., Cowan, Morton J., Dvorak, Christopher C., Haddad, Elie, Puck, Jennifer M., and Kohn, Donald B.

Published
2022
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11. HLA-Haploidentical Hematopoietic Cell Transplantation for Treatment of Nonmalignant Diseases Using Nonmyeloablative Conditioning and Post-Transplant Cyclophosphamide

Author

Mallhi, Kanwaldeep K., Srikanthan, Meera A., Baker, Kelsey K., Frangoul, Haydar A., Torgerson, Troy R., Petrovic, Aleksandra, Geddis, Amy E., Carpenter, Paul A., Baker, K. Scott, Sandmaier, Brenda M., Thakar, Monica S., Skoda-Smith, Suzanne, Kiem, Hans-Peter, Storb, Rainer, Woolfrey, Ann E., and Burroughs, Lauri M.

Published
2020
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13. Expanded HCT-CI Definitions Capture Comorbidity Better for Younger Patients of Allogeneic HCT for Nonmalignant Diseases

Author

Broglie, Larisa, Friend, Brian D., Chhabra, Saurabh, Logan, Brent R., Bupp, Caitrin, Schiller, Gary, Savani, Bipin N., Stadtmauer, Edward, Abraham, Allistair A., Aljurf, Mahmoud, Badawy, Sherif M., Perez, Miguel Angel Diaz, Guinan, Eva C., Hashem, Hasan, Krem, Maxwell M., Lazarus, Hillard M., Rotz, Seth J., Wirk, Baldeep, Yared, Jean A., Pasquini, Marcelo, Thakar, Monica S., and Sorror, Mohamed L.

Published
2023
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14. Adapting the HCT-CI Definitions for Children, Adolescents, and Young Adults with Hematologic Malignancies Undergoing Allogeneic Hematopoietic Cell Transplantation

Author

Friend, Brian D., Broglie, Larisa, Logan, Brent R., Chhabra, Saurabh, Bupp, Caitrin, Schiller, Gary, Beitinjaneh, Amer, Perez, Miguel Angel Diaz, Guilcher, Gregory M.T., Hashem, Hasan, Hildebrandt, Gerhard C., Krem, Maxwell M., Lazarus, Hillard M., Nishihori, Taiga, Nusrat, Roomi, Rotz, Seth J., Wirk, Baldeep, Wieduwilt, Matthew, Pasquini, Marcelo, Savani, Bipin N., Stadtmauer, Edward A., Sorror, Mohamed L., and Thakar, Monica S.

Published
2023
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15. Correction to: Infections in Infants with SCID: Isolation, Infection Screening and Prophylaxis in PIDTC Centers

Author

Dorsey, Morna, Wright, Nicola A. M., Chaimowitz, Natalia S., Dávila Saldaña, Blachy J., Miller, Holly, Keller, Michael D., Thakar, Monica S., Shah, Ami J., Abu-Arja, Rolla, Andolina, Jeffrey, Aquino, Victor, Barnum, J. L., Bednarski, Jeffrey J., Bhatia, Monica, Bonilla, Francisco A., Butte, Manish J., Bunin, Nancy J., Burroughs, Lauri M., Chandra, Sharat, Chaudhury, Sonali, Chen, Karin, Chong, Hey, Cuvelier, Geoff, Dalal, Jignesh, DeFelice, Magee L., DeSantes, Kenneth B., Forbes, Lisa R., Gillio, Alfred, Goldman, Fred, Joshi, Avni Y., Kapoor, Neena, Knutsen, Alan P., Kobrynski, Lisa, Lieberman, Jay A., Leiding, Jennifer W., Oshrine, Benjamin, Patel, Kiran P., Prockop, Susan, Quigg, Troy C., Quinones, Ralph, Schultz, Kirk R., Seroogy, Christine, Shyr, David, Siegel, Subhadra, Smith, Angela R., Torgerson, Troy R., Vander Lugt, Mark T., Yu, Lolie C., Cowan, Morton J., Buckley, Rebecca H., Dvorak, Christopher C., Griffith, Linda M., Haddad, Elie, Kohn, Donald B., Logan, Brent, Notarangelo, Luigi D., Pai, Sung-Yun, Puck, Jennifer, Pulsipher, Michael A., and Heimall, Jennifer

Published
2021
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17. Posttransplantation late complications increase over time for patients with SCID: A Primary Immune Deficiency Treatment Consortium (PIDTC) landmark study

Author

Eissa, Hesham, primary, Thakar, Monica S., additional, Shah, Ami J., additional, Logan, Brent R., additional, Griffith, Linda M., additional, Dong, Huaying, additional, Parrott, Roberta E., additional, O’Reilly, Richard J., additional, Dara, Jasmeen, additional, Kapoor, Neena, additional, Forbes Satter, Lisa, additional, Chandra, Sharat, additional, Kapadia, Malika, additional, Chandrakasan, Shanmuganathan, additional, Knutsen, Alan, additional, Jyonouchi, Soma C., additional, Molinari, Lyndsay, additional, Rayes, Ahmad, additional, Ebens, Christen L., additional, Teira, Pierre, additional, Dávila Saldaña, Blachy J., additional, Burroughs, Lauri M., additional, Chaudhury, Sonali, additional, Chellapandian, Deepak, additional, Gillio, Alfred P., additional, Goldman, Fredrick, additional, Malech, Harry L., additional, DeSantes, Kenneth, additional, Cuvelier, Geoff D.E., additional, Rozmus, Jacob, additional, Quinones, Ralph, additional, Yu, Lolie C., additional, Broglie, Larisa, additional, Aquino, Victor, additional, Shereck, Evan, additional, Moore, Theodore B., additional, Vander Lugt, Mark T., additional, Mousallem, Talal I., additional, Oved, Joeseph H., additional, Dorsey, Morna, additional, Abdel-Azim, Hisham, additional, Martinez, Caridad, additional, Bleesing, Jacob H., additional, Prockop, Susan, additional, Kohn, Donald B., additional, Bednarski, Jeffrey J., additional, Leiding, Jennifer, additional, Marsh, Rebecca A., additional, Torgerson, Troy, additional, Notarangelo, Luigi D., additional, Pai, Sung-Yun, additional, Pulsipher, Michael A., additional, Puck, Jennifer M., additional, Dvorak, Christopher C., additional, Haddad, Elie, additional, Buckley, Rebecca H., additional, Cowan, Morton J., additional, and Heimall, Jennifer, additional

Published
2023
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19. SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery

Author

Haddad, Elie, Logan, Brent R., Griffith, Linda M., Buckley, Rebecca H., Parrott, Roberta E., Prockop, Susan E., Small, Trudy N., Chaisson, Jessica, Dvorak, Christopher C., Murnane, Megan, Kapoor, Neena, Abdel-Azim, Hisham, Hanson, Imelda C., Martinez, Caridad, Bleesing, Jack J.H., Chandra, Sharat, Smith, Angela R., Cavanaugh, Matthew E., Jyonouchi, Soma, Sullivan, Kathleen E., Burroughs, Lauri, Skoda-Smith, Suzanne, Haight, Ann E., Tumlin, Audrey G., Quigg, Troy C., Taylor, Candace, Dávila Saldaña, Blachy J., Keller, Michael D., Seroogy, Christine M., Desantes, Kenneth B., Petrovic, Aleksandra, Leiding, Jennifer W., Shyr, David C., Decaluwe, Hélène, Teira, Pierre, Gillio, Alfred P., Knutsen, Alan P., Moore, Theodore B., Kletzel, Morris, Craddock, John A., Aquino, Victor, Davis, Jeffrey H., Yu, Lolie C., Cuvelier, Geoffrey D.E., Bednarski, Jeffrey J., Goldman, Frederick D., Kang, Elizabeth M., Shereck, Evan, Porteus, Matthew H., Connelly, James A., Fleisher, Thomas A., Malech, Harry L., Shearer, William T., Szabolcs, Paul, Thakar, Monica S., Vander Lugt, Mark T., Heimall, Jennifer, Yin, Ziyan, Pulsipher, Michael A., Pai, Sung-Yun, Kohn, Donald B., Puck, Jennifer M., Cowan, Morton J., O'Reilly, Richard J., and Notarangelo, Luigi D.

Published
2018
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21. Supplementary Methods from Biodistributions, Myelosuppression, and Toxicities in Mice Treated with an Anti-CD45 Antibody Labeled with the α-Emitting Radionuclides Bismuth-213 or Astatine-211

Author

Nakamae, Hirohisa, primary, Wilbur, D. Scott, primary, Hamlin, Donald K., primary, Thakar, Monica S., primary, Santos, Erlinda B., primary, Fisher, Darrell R., primary, Kenoyer, Aimee L., primary, Pagel, John M., primary, Press, Oliver W., primary, Storb, Rainer, primary, and Sandmaier, Brenda M., primary

Published
2023
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22. Data from Biodistributions, Myelosuppression, and Toxicities in Mice Treated with an Anti-CD45 Antibody Labeled with the α-Emitting Radionuclides Bismuth-213 or Astatine-211

Author

Nakamae, Hirohisa, primary, Wilbur, D. Scott, primary, Hamlin, Donald K., primary, Thakar, Monica S., primary, Santos, Erlinda B., primary, Fisher, Darrell R., primary, Kenoyer, Aimee L., primary, Pagel, John M., primary, Press, Oliver W., primary, Storb, Rainer, primary, and Sandmaier, Brenda M., primary

Published
2023
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23. Revisiting Pre-Transplant Testicular Radiation for Relapse Prophylaxis in Allogeneic Hematopoietic Cell Transplantation (HCT) for Acute Lymphoblastic Leukemia (ALL)

Author

Summers, Corinne, primary, Bhatt, Neel S., additional, Jenssen, Kari, additional, Hoover, Alex, additional, Ebens, Christen L., additional, Schaefer, Edo, additional, Cairo, Mitchell S., additional, Carpenter, Paul A., additional, Dahlberg, Ann, additional, Hadland, Brandon, additional, Bleakley, Marie, additional, and Thakar, Monica S., additional

Published
2023
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24. Event Free Survival in Severe Combined Immune Deficiency (SCID) Infants after Conditioned Umbilical Cord Blood Transplantation (UCBT) Benefits from Omitting Serotherapy

Author

Martinez, Caridad, primary, Logan, Brent, additional, Liu, Xuerong, additional, Dvorak, Christopher C., additional, Madden, Lisa, additional, Molinari, Lyndsay, additional, Cowan, Morton J., additional, Pai, Sung-Yun, additional, Haddad, Elie, additional, Puck, Jennifer, additional, Kohn, Donald B., additional, Griffith, Linda M., additional, Pulsipher, Michael, additional, Leiding, Jennifer W., additional, Notarangelo, Luigi D., additional, Torgerson, Troy, additional, Marsh, Rebecca A., additional, Cuvelier, Geoff D.E., additional, Prockop, Susan, additional, Buckley, Rebecca H., additional, Kuo, Caroline Y., additional, Yip, Alison, additional, Hershfield, Michael S., additional, Parrott, Roberta E, additional, Ebens, Christen L., additional, Moore, Theodore B., additional, O’Reilly, Richard J., additional, Kapadia, Malika, additional, Kapoor, Neena, additional, Satter, Lisa Forbes, additional, Burroughs, Lauri M., additional, Petrovic, Aleksandra, additional, Thakar, Monica S., additional, Chellapandian, Deepak, additional, Heimall, Jennifer R., additional, Shyr, David C., additional, Bednarski, Jeffrey J, additional, Rayes, Ahmad, additional, Chandrakasan, Shanmuganathan, additional, Quigg, Troy C., additional, Davila, Blachy J, additional, DeSantes, Kenneth, additional, Eissa, Hesham, additional, Goldman, Frederick, additional, Rozmus, Jacob, additional, Shah, Ami J, additional, Lugt, Mark Vander, additional, Keller, Michael D., additional, Sullivan, Kathleen E., additional, Jyonouchi, Soma, additional, Seroogy, Christine, additional, Decaluwe, Helene, additional, Teira, Pierre, additional, Knutsen, Alan P., additional, Kletzel, Morris, additional, Aquino, Victor, additional, Davis, Jeffrey H, additional, and Szabolcs, Paul, additional

Published
2023
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25. Revisiting the Role of Post-Transplant Central Nervous System Prophylaxis in Allogeneic Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia

Author

Bhatt, Neel S., primary, Summers, Corinne, additional, Jenssen, Kari, additional, Hoover, Alex, additional, Ebens, Christen L., additional, Schaefer, Edo, additional, Cairo, Mitchell S., additional, Carpenter, Paul A., additional, Dahlberg, Ann, additional, Hadland, Brandon, additional, Bleakley, Marie, additional, and Thakar, Monica S., additional

Published
2023
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31. Expanded HCT-CI Definitions Capture Comorbidity Better for Younger Patients of Allogeneic HCT for Nonmalignant Diseases

Author

Broglie, Larisa, primary, Friend, Brian D., additional, Chhabra, Saurabh, additional, Logan, Brent R., additional, Bupp, Caitrin, additional, Schiller, Gary, additional, Savani, Bipin N., additional, Stadtmauer, Edward, additional, Abraham, Allistair A., additional, Aljurf, Mahmoud, additional, Badawy, Sherif M., additional, Perez, Miguel Angel Diaz, additional, Guinan, Eva C., additional, Hashem, Hasan, additional, Krem, Maxwell M., additional, Lazarus, Hillard M., additional, Rotz, Seth J., additional, Wirk, Baldeep, additional, Yared, Jean A., additional, Pasquini, Marcelo, additional, Thakar, Monica S., additional, and Sorror, Mohamed L., additional

Published
2022
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32. 116 - Event Free Survival in Severe Combined Immune Deficiency (SCID) Infants after Conditioned Umbilical Cord Blood Transplantation (UCBT) Benefits from Omitting Serotherapy

Author

Martinez, Caridad, Logan, Brent, Liu, Xuerong, Dvorak, Christopher C., Madden, Lisa, Molinari, Lyndsay, Cowan, Morton J., Pai, Sung-Yun, Haddad, Elie, Puck, Jennifer, Kohn, Donald B., Griffith, Linda M., Pulsipher, Michael, Leiding, Jennifer W., Notarangelo, Luigi D., Torgerson, Troy, Marsh, Rebecca A., Cuvelier, Geoff D.E., Prockop, Susan, Buckley, Rebecca H., Kuo, Caroline Y., Yip, Alison, Hershfield, Michael S., Parrott, Roberta E, Ebens, Christen L., Moore, Theodore B., O’Reilly, Richard J., Kapadia, Malika, Kapoor, Neena, Satter, Lisa Forbes, Burroughs, Lauri M., Petrovic, Aleksandra, Thakar, Monica S., Chellapandian, Deepak, Heimall, Jennifer R., Shyr, David C., Bednarski, Jeffrey J, Rayes, Ahmad, Chandrakasan, Shanmuganathan, Quigg, Troy C., Davila, Blachy J, DeSantes, Kenneth, Eissa, Hesham, Goldman, Frederick, Rozmus, Jacob, Shah, Ami J, Lugt, Mark Vander, Keller, Michael D., Sullivan, Kathleen E., Jyonouchi, Soma, Seroogy, Christine, Decaluwe, Helene, Teira, Pierre, Knutsen, Alan P., Kletzel, Morris, Aquino, Victor, Davis, Jeffrey H, and Szabolcs, Paul

Published
2023
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33. Treosulfan-Based Conditioning and Hematopoietic Cell Transplantation for Nonmalignant Diseases: A Prospective Multicenter Trial

Author

Burroughs, Lauri M., Nemecek, Eneida R., Torgerson, Troy R., Storer, Barry E., Talano, Julie-An, Domm, Jennifer, Giller, Roger H., Shimamura, Akiko, Delaney, Colleen, Skoda-Smith, Suzanne, Thakar, Monica S., Baker, K. Scott, Rawlings, David J., Englund, Janet A., Flowers, Mary E.D., Deeg, H. Joachim, Storb, Rainer, and Woolfrey, Ann E.

Published
2014
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34. Differential use of the hematopoietic cell transplantation-comorbidity index among adult and pediatric transplant physicians

Author

Broglie, Larisa, primary, Friend, Brian D., additional, Chhabra, Saurabh, additional, Bupp, Caitrin, additional, Schiller, Gary J., additional, Logan, Brent, additional, Pasquini, Marcelo C., additional, Savani, Bipin, additional, Stadtmauer, Edward A., additional, Thakar, Monica S., additional, and Sorror, Mohamed, additional

Published
2022
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35. Outcomes after Hematopoietic Cell Transplant and Gene Therapy for Adenosine Deaminase (ADA) Severe Combined Immune Deficiency: A Combined Analysis from the Primary Immune Deficiency Treatment Consortium (PIDTC) 6901 and 6902 Studies

Author

Cuvelier, Geoff D.E., primary, Logan, Brent, additional, Prockop, Susan E., additional, Buckley, Rebecca H., additional, Kuo, Caroline Y., additional, Griffith, Linda M., additional, Liu, Xuerong, additional, Yip, Alison, additional, Hershfield, Michael S., additional, Parrott, Roberta E, additional, Ebens, Christen L., additional, Moore, Theodore B., additional, O’Reilly, Richard J., additional, Pai, Sung-Yun, additional, Kapadia, Malika, additional, Kapoor, Neena, additional, Forbes Satter, Lisa R., additional, Martinez, Caridad, additional, Burroughs, Lauri M., additional, Petrovic, Aleksandra, additional, Thakar, Monica S., additional, Chellapandian, Deepak, additional, Heimall, Jennifer, additional, Shyr, David C., additional, Rayes, Ahmad, additional, Bednarski II, Jeffrey J., additional, Chandra, Sharat, additional, Chandrakasan, Shanmuganathan, additional, Gillio, Alfred P., additional, Madden, Lisa, additional, Quigg, Troy C., additional, Caywood, Emi H., additional, Dávila Saldaña, Blachy J, additional, DeSantes, Kenneth, additional, Eissa, Hesham, additional, Goldman, Frederick, additional, Rozmus, Jacob, additional, Shah, Ami J, additional, Vander Lugt, Mark T., additional, Pulsipher, Mike A., additional, Notarangelo, Luigi D., additional, Cowan, Morton J., additional, Dvorak, Christopher C., additional, Haddad, Elie, additional, Puck, Jennifer, additional, and Kohn, Donald B., additional

Published
2022
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36. A Primary Immune Deficiency Treatment Consortium (PIDTC) Study of Chronic and Late Onset Medical Complications after Initial Hematopoietic Cell Transplantation (HCT) for Severe Combined Immunodeficiency Disease (SCID)

Author

Eissa, Hesham, primary, Thakar, Monica S., additional, Shah, Ami J, additional, Buckley, Rebecca H., additional, Logan, Brent, additional, Griffith, Linda M., additional, Dong, Huaying, additional, O’Reilly, Richard J., additional, Kapoor, Neena, additional, Satter, Lisa Forbes, additional, Chandra, Sharat, additional, Bleesing, Jack J., additional, Kapadia, Malika, additional, Parrott, Roberta E, additional, Chandrakasan, Shanmuganathan, additional, Bednarski II, Jeffrey J., additional, Jyonouchi, Soma, additional, Madden, Lisa M., additional, Rayes, Ahmad, additional, Ebens, Christen L., additional, Teira, Pierre, additional, Dávila Saldaña, Blachy J, additional, Burroughs, Lauri M., additional, Prockop, Susan E., additional, Williams, Olatundun, additional, Chellapandian, Deepak, additional, Gillio, Alfred P., additional, Goldman, Frederick, additional, Malech, Harry L., additional, DeSantes, Kenneth, additional, Cuvelier, Geoff D.E., additional, Rozmus, Jacob, additional, Quinones, Ralph, additional, Yu, Lolie C., additional, Broglie, Larisa, additional, Aquino, Victor, additional, Shereck, Evan, additional, Moore, Theodore B., additional, Martinez, Caridad, additional, Vander Lugt, Mark T., additional, Leiding, Jennifer W., additional, Torgerson, Troy, additional, Pai, Sung-Yun, additional, Pulsipher, Mike A., additional, Notarangelo, Luigi D., additional, Puck, Jennifer, additional, Dvorak, Christopher C., additional, Haddad, Elie, additional, Cowan, Morton J., additional, and Heimall, Jennifer, additional

Published
2022
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40. Case Series

Author

Knight, Benjamin, primary, Anderson, Lynnette, additional, Lerner, Diana, additional, Phelan, Rachel, additional, and Thakar, Monica S., additional

Published
2021
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43. Role of GATA2 in Human NK Cell Development

Author

Wang, Dandan, primary, Uyemura, Bradley, additional, Hashemi, Elaheh, additional, Bjorgaard, Stacey, additional, Riese, Matthew, additional, Verbsky, James, additional, Thakar, Monica S., additional, and Malarkannan, Subramaniam, additional

Published
2021
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44. Correction to: Infections in Infants with SCID: Isolation, Infection Screening and Prophylaxis in PIDTC Centers

Author

Dorsey, Morna, primary, Wright, Nicola A. M., additional, Chaimowitz, Natalia S., additional, Dávila Saldaña, Blachy J., additional, Miller, Holly, additional, Keller, Michael D., additional, Thakar, Monica S., additional, Shah, Ami J., additional, Abu-Arja, Rolla, additional, Andolina, Jeffrey, additional, Aquino, Victor, additional, Barnum, J. L., additional, Bednarski, Jeffrey J., additional, Bhatia, Monica, additional, Bonilla, Francisco A., additional, Butte, Manish J., additional, Bunin, Nancy J., additional, Burroughs, Lauri M., additional, Chandra, Sharat, additional, Chaudhury, Sonali, additional, Chen, Karin, additional, Chong, Hey, additional, Cuvelier, Geoff, additional, Dalal, Jignesh, additional, DeFelice, Magee L., additional, DeSantes, Kenneth B., additional, Forbes, Lisa R., additional, Gillio, Alfred, additional, Goldman, Fred, additional, Joshi, Avni Y., additional, Kapoor, Neena, additional, Knutsen, Alan P., additional, Kobrynski, Lisa, additional, Lieberman, Jay A., additional, Leiding, Jennifer W., additional, Oshrine, Benjamin, additional, Patel, Kiran P., additional, Prockop, Susan, additional, Quigg, Troy C., additional, Quinones, Ralph, additional, Schultz, Kirk R., additional, Seroogy, Christine, additional, Shyr, David, additional, Siegel, Subhadra, additional, Smith, Angela R., additional, Torgerson, Troy R., additional, Vander Lugt, Mark T., additional, Yu, Lolie C., additional, Cowan, Morton J., additional, Buckley, Rebecca H., additional, Dvorak, Christopher C., additional, Griffith, Linda M., additional, Haddad, Elie, additional, Kohn, Donald B., additional, Logan, Brent, additional, Notarangelo, Luigi D., additional, Pai, Sung-Yun, additional, Puck, Jennifer, additional, Pulsipher, Michael A., additional, and Heimall, Jennifer, additional

Published
2020
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48. Infections in Infants with SCID: Isolation, Infection Screening, and Prophylaxis in PIDTC Centers

Author

Dorsey, Morna J., primary, Wright, Nicola A. M., additional, Chaimowitz, Natalia S., additional, Dávila Saldaña, Blachy J., additional, Miller, Holly, additional, Keller, Michael D., additional, Thakar, Monica S., additional, Shah, Ami J., additional, Abu-Arja, Rolla, additional, Andolina, Jeffrey, additional, Aquino, Victor, additional, Barnum, J. L., additional, Bednarski, Jeffrey J., additional, Bhatia, Monica, additional, Bonilla, Francisco A., additional, Butte, Manish J., additional, Bunin, Nancy J., additional, Chandra, Sharat, additional, Chaudhury, Sonali, additional, Chen, Karin, additional, Chong, Hey, additional, Cuvelier, Geoffrey D. E., additional, Dalal, Jignesh, additional, DeFelice, Magee L., additional, DeSantes, Kenneth B., additional, Forbes, Lisa R., additional, Gillio, Alfred, additional, Goldman, Fred, additional, Joshi, Avni Y., additional, Kapoor, Neena, additional, Knutsen, Alan P., additional, Kobrynski, Lisa, additional, Lieberman, Jay A., additional, Leiding, Jennifer W., additional, Oshrine, Benjamin, additional, Patel, Kiran P., additional, Prockop, Susan, additional, Quigg, Troy C., additional, Quinones, Ralph, additional, Schultz, Kirk R., additional, Seroogy, Christine, additional, Shyr, David, additional, Siegel, Subhadra, additional, Smith, Angela R., additional, Torgerson, Troy R., additional, Vander Lugt, Mark T., additional, Yu, Lolie C., additional, Cowan, Morton J., additional, Buckley, Rebecca H., additional, Dvorak, Christopher C., additional, Griffith, Linda M., additional, Haddad, Elie, additional, Kohn, Donald B., additional, Logan, Brent, additional, Notarangelo, Luigi D., additional, Pai, Sung-Yun, additional, Puck, Jennifer, additional, Pulsipher, Michael A., additional, and Heimall, Jennifer, additional

Published
2020
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49. Excellent outcomes following hematopoietic cell transplantation for Wiskott-Aldrich syndrome: a PIDTC report

Author

Burroughs, Lauri M., primary, Petrovic, Aleksandra, primary, Brazauskas, Ruta, primary, Liu, Xuerong, primary, Griffith, Linda M., primary, Ochs, Hans D., primary, Bleesing, Jack J., primary, Edwards, Stephanie, primary, Dvorak, Christopher C., primary, Chaudhury, Sonali, primary, Prockop, Susan E., primary, Quinones, Ralph, primary, Goldman, Frederick D., primary, Quigg, Troy C., primary, Chandrakasan, Shanmuganathan, primary, Smith, Angela R., primary, Parikh, Suhag, primary, Dávila Saldaña, Blachy J., primary, Thakar, Monica S., primary, Phelan, Rachel, primary, Shenoy, Shalini, primary, Forbes, Lisa R., primary, Martinez, Caridad, primary, Chellapandian, Deepak, primary, Shereck, Evan, primary, Miller, Holly K., primary, Kapoor, Neena, primary, Barnum, Jessie L., primary, Chong, Hey, primary, Shyr, David C., primary, Chen, Karin, primary, Abu-Arja, Rolla, primary, Shah, Ami J., primary, Weinacht, Katja G., primary, Moore, Theodore B., primary, Joshi, Avni, primary, DeSantes, Kenneth B., primary, Gillio, Alfred P., primary, Cuvelier, Geoffrey D. E., primary, Keller, Michael D., primary, Rozmus, Jacob, primary, Torgerson, Troy, primary, Pulsipher, Michael A., primary, Haddad, Elie, primary, Sullivan, Kathleen E., primary, Logan, Brent R., primary, Kohn, Donald B., primary, Puck, Jennifer M., primary, Notarangelo, Luigi D., primary, Pai, Sung-Yun, primary, Rawlings, David J., primary, and Cowan, Morton J., primary

Published
2020
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50. Phase II trial using haploidentical hematopoietic cell transplantation (HCT) followed by donor natural killer (NK) cell infusion and sirolimus maintenance for patients with high-risk solid tumors.

Author

Thakar, Monica S., primary, Browning, Meghen, additional, Hari, Parameswaran, additional, Charlson, John A., additional, Margolis, David A., additional, Logan, Brent, additional, Schloemer, Nathan, additional, Kelly, Michael E., additional, Newman, Amy, additional, Johnson, Bryon, additional, Keever-Taylor, Carolyn Anne, additional, and Malarkannan, Subramaniam, additional

Published
2020
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