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8. Accidental ND:YAG laser injuries to the macula

Author

Thach, Allen B., Lopez, Pedro F., Snady-McCoy, Lory C., Golub, Barry M., and Frambach, Donald A.

Subjects
Macula lutea -- Injuries, Lasers -- Accidents, Health
Published
1995

13. Ophthalmic Care of the Combat Casualty

Author

WALTER REED ARMY MEDICAL CENTER WASHINGTON DC, Lounsbury, Dave E., Bellamy, Ronald F., Zajtchuk, Russ, Thach, Allen B., WALTER REED ARMY MEDICAL CENTER WASHINGTON DC, Lounsbury, Dave E., Bellamy, Ronald F., Zajtchuk, Russ, and Thach, Allen B.

Abstract

Along with saving the lives and limbs of our soldiers, sailors, and airmen injured in battle, the preservation of their eyes and eyesight is an extremely important goal. Despite comprising as little as 0.1% of the total body surface area and 0.27% of the frontal silhouette, the proportion of eye injuries in nonfatal casualties has been escalating in recent conflicts (Table). Several reasons account for the increasing risk of eye injuries: 1. preferential exposure of the eyes during combat (eg, foxholes, tank turrets); 2. improved body armor protecting the head, thorax, and abdomen, leading to fewer fatal injuries to these regions of the body; 3. improved surgical techniques and rapid evacuation of the wounded, which allow physicians to repair wounds that at one time would have resulted in the death of a soldier; and 4. improved munitions, which create more and smaller fragments that can cause severe, even blinding, injuries., The original document contains color images.

Published
2003

14. Two-Year Outcomes of the Ranibizumab for Edema of the mAcula in Diabetes (READ-2) Study

Author

Nguyen, Quan Dong, primary, Shah, Syed Mahmood, additional, Khwaja, Afsheen A., additional, Channa, Roomasa, additional, Hatef, Elham, additional, Do, Diana V., additional, Boyer, David, additional, Heier, Jeffery S., additional, Abraham, Prema, additional, Thach, Allen B., additional, Lit, Eugene S., additional, Foster, Bradley S., additional, Kruger, Erik, additional, Dugel, Pravin, additional, Chang, Thomas, additional, Das, Arup, additional, Ciulla, Thomas A., additional, Pollack, John S., additional, Lim, Jennifer I., additional, Eliot, Dean, additional, and Campochiaro, Peter A., additional

Published
2010
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15. Severe Eye Injuries in the War in Iraq, 2003–2005

Author

Thach, Allen B., primary, Johnson, Anthony J., additional, Carroll, Robert B., additional, Huchun, Ava, additional, Ainbinder, Darryl J., additional, Stutzman, Richard D., additional, Blaydon, Sean M., additional, DeMartelaere, Sheri L., additional, Mader, Thomas H., additional, Slade, Clifton S., additional, George, Roger K., additional, Ritchey, John P., additional, Barnes, Scott D., additional, and Fannin, Lilia A., additional

Published
2008
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19. Eye Injuries in the U.S. Armed Forces

Author

Lau, Jimmy J.S., primary, Thach, Allen B., additional, Burden, James H., additional, Ward, Thomas P., additional, Hshieh, Paul B., additional, and Hollifield, Rodney D., additional

Published
2000
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20. Eye injuries in a terrorist bombing43The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense.44The authors have no financial interest in any product noted in this article.

Author

Thach, Allen B, primary, Ward, Thomas P, additional, Hollifield, Rodney D, additional, Cockerham, Kimberly, additional, Birdsong, Richard, additional, and Kramer, Kenyon K, additional

Published
2000
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21. Ocular injuries from paintball pellets

Author

Thach, Allen B, primary, Ward, Thomas P, additional, Hollifield, Rodney D, additional, Dugel, Pravin U, additional, Sipperley, Jack O, additional, Marx, Jeffrey L, additional, Abrams, Donald A, additional, Wroblewski, Keith J, additional, Sonkin, Peter L, additional, Birdsong, Richard H, additional, and Dunlap, Weldon A, additional

Published
1999
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23. Open globe injuries in children

Author

Rostomian, Khodam, primary, Thach, Allen B., additional, Isfahani, Amir, additional, Pakkar, Alireza, additional, Pakkar, Roya, additional, and Borchert, Mark, additional

Published
1998
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24. Authors' reply

Author

Dugel, Pravin U., primary, Heuer, Dale K., additional, Thach, Allen B., additional, Baerveldt, George, additional, Lee, Paul P., additional, Lloyd, Mary Ann, additional, Minckler, Don S., additional, and Green, Ronald L., additional

Published
1997
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30. Detecting Alzheimer's Disease

Author

Marx, Jeffrey L., primary, Kumar, Sanjiv R., additional, Thach, Allen B., additional, Kiat-Winarko, Tien, additional, and Frambach, Donald A., additional

Published
1995
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34. Time to Clinically Significant Visual Acuity Gains after Ranibizumab Treatment for Retinal Vein Occlusion BRAVO and CRUISE Trials

Author

Thach, Allen B., Yau, Linda, Hoang, Carol, and Tuomi, Lisa

Subjects
genetic structures
Abstract

PurposeTo assess time to first achievement of clinically significant visual acuity (VA) gains from baseline in patients with retinal vein occlusion (RVO) receiving ranibizumab versus sham treatment.DesignPost hoc analyses of 2 phase 3 clinical trials assessing efficacy and safety of ranibizumab in patients with branch RVO (Ranibizumab for the Treatment of Macular Edema following Branch Retinal Vein Occlusion: Evaluation of Efficacy and Safety [BRAVO] study; NCT00061594) and central RVO (Ranibizumab for the Treatment of Macular Edema after Central Retinal Vein Occlusion Study: Evaluation of Efficacy and Safety [CRUISE]; NCT00056836) over 12 months.ParticipantsSeven hundred eighty-nine patients (BRAVO, n = 397; CRUISE, n = 392).InterventionRandomization to monthly intraocular ranibizumab injections (0.3 mg/0.5 mg) or sham. After 6 monthly injections (treatment period), patients meeting prespecified criteria received as-needed (pro re nata [PRN]) ranibizumab at their assigned dose (sham patients, ranibizumab 0.5 mg) through month 12 (observation period). BRAVO patients meeting specific eligibility criteria could receive rescue laser treatment once during the treatment and once during the observation periods.Main Outcome MeasuresTime to first gain of 15 letters or more from baseline, analyzed using Kaplan-Meier methods. To evaluate the effect of delaying ranibizumab treatment, sham patients' VA data also were analyzed, with month 6 considered as baseline to assess vision gains during the 6 months of receiving ranibizumab PRN.ResultsMedian time to first 15-letter or more gain from baseline was 12.0 (sham), 4.8 (ranibizumab 0.3 mg), and 4.0 months (ranibizumab 0.5 mg) in BRAVO and 12.2, 5.9, and 5.2 months, respectively, in CRUISE. The cumulative proportion of patients who had ever gained 15 letters or more from baseline by month 12 was 50% (sham), 68% (ranibizumab 0.3 mg), and 71% (ranibizumab 0.5 mg) in BRAVO and 42%, 61%, and 66%, respectively, in CRUISE. After 6 months of ranibizumab PRN treatment, a cumulative 10.8% (BRAVO) and 26.2% (CRUISE) of initially sham-treated patients ever gained 15 letters or more.ConclusionsThis retrospective analysis shows that more than 50% of patients treated with monthly ranibizumab achieved clinically significant vision gains during the initial 6 months of treatment, which largely were maintained using PRN treatment to 12 months. In comparison, less than 50% of patients initially randomized to sham (and later receiving ranibizumab 0.5 mg PRN treatment) ever achieved clinically significant vision gains. These results suggest that initiating treatment immediately after diagnosis may provide the greatest vision gains. The potential benefits of early treatment should be evaluated further in prospective clinical studies.

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37. Ophthalmic Care of the Combat Casualty (Book).

Author

Thach, Allen B. and Nolan, Brian T.

Subjects
*OPHTHALMOLOGY, *NONFICTION
Abstract

Reviews the book "Ophthalmic Care of the Combat Casualty," by Allen B. Thach.

Published
2004

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