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1. Risk factors for difficult thyroidectomy and postoperative morbidity do not match: retrospective study from an endocrine surgery academic referral centre

Author: Prete, F. P., Panzera, P. C., Di Meo, G., Pasculli, A., Sgaramella, L. I., Calculli, G., Dimonte, R., Ferrarese, F., Testini, M., and Gurrado, A.
Published: 2022
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2. 2023 WSES guidelines for the prevention, detection, and management of iatrogenic urinary tract injuries (IUTIs) during emergency digestive surgery

Author: De'Angelis, N, Schena, C, Marchegiani, F, Reitano, E, De Simone, B, Wong, G, Martinez-Perez, A, Abu-Zidan, F, Agnoletti, V, Aisoni, F, Ammendola, M, Ansaloni, L, Bala, M, Biffl, W, Ceccarelli, G, Ceresoli, M, Chiara, O, Chiarugi, M, Cimbanassi, S, Coccolini, F, Coimbra, R, Di Saverio, S, Diana, M, Dioguardi Burgio, M, Fraga, G, Gavriilidis, P, Gurrado, A, Inchingolo, R, Ingels, A, Ivatury, R, Kashuk, J, Khan, J, Kirkpatrick, A, Kim, F, Kluger, Y, Lakkis, Z, Leppaniemi, A, Maier, R, Memeo, R, Moore, E, Ordonez, C, Peitzman, A, Pellino, G, Picetti, E, Pikoulis, M, Pisano, M, Podda, M, Romeo, O, Rosa, F, Tan, E, Ten Broek, R, Testini, M, Tian Wei Cheng, B, Weber, D, Sacco, E, Sartelli, M, Tonsi, A, Dal Moro, F, Catena, F, de'Angelis N., Schena C. A., Marchegiani F., Reitano E., De Simone B., Wong G. Y. M., Martinez-Perez A., Abu-Zidan F. M., Agnoletti V., Aisoni F., Ammendola M., Ansaloni L., Bala M., Biffl W., Ceccarelli G., Ceresoli M., Chiara O., Chiarugi M., Cimbanassi S., Coccolini F., Coimbra R., Di Saverio S., Diana M., Dioguardi Burgio M., Fraga G., Gavriilidis P., Gurrado A., Inchingolo R., Ingels A., Ivatury R., Kashuk J. L., Khan J., Kirkpatrick A. W., Kim F. J., Kluger Y., Lakkis Z., Leppaniemi A., Maier R. V., Memeo R., Moore E. E., Ordonez C. A., Peitzman A. B., Pellino G., Picetti E., Pikoulis M., Pisano M., Podda M., Romeo O., Rosa F., Tan E., Ten Broek R. P., Testini M., Tian Wei Cheng B. A., Weber D., Sacco E., Sartelli M., Tonsi A., Dal Moro F., Catena F., De'Angelis, N, Schena, C, Marchegiani, F, Reitano, E, De Simone, B, Wong, G, Martinez-Perez, A, Abu-Zidan, F, Agnoletti, V, Aisoni, F, Ammendola, M, Ansaloni, L, Bala, M, Biffl, W, Ceccarelli, G, Ceresoli, M, Chiara, O, Chiarugi, M, Cimbanassi, S, Coccolini, F, Coimbra, R, Di Saverio, S, Diana, M, Dioguardi Burgio, M, Fraga, G, Gavriilidis, P, Gurrado, A, Inchingolo, R, Ingels, A, Ivatury, R, Kashuk, J, Khan, J, Kirkpatrick, A, Kim, F, Kluger, Y, Lakkis, Z, Leppaniemi, A, Maier, R, Memeo, R, Moore, E, Ordonez, C, Peitzman, A, Pellino, G, Picetti, E, Pikoulis, M, Pisano, M, Podda, M, Romeo, O, Rosa, F, Tan, E, Ten Broek, R, Testini, M, Tian Wei Cheng, B, Weber, D, Sacco, E, Sartelli, M, Tonsi, A, Dal Moro, F, Catena, F, de'Angelis N., Schena C. A., Marchegiani F., Reitano E., De Simone B., Wong G. Y. M., Martinez-Perez A., Abu-Zidan F. M., Agnoletti V., Aisoni F., Ammendola M., Ansaloni L., Bala M., Biffl W., Ceccarelli G., Ceresoli M., Chiara O., Chiarugi M., Cimbanassi S., Coccolini F., Coimbra R., Di Saverio S., Diana M., Dioguardi Burgio M., Fraga G., Gavriilidis P., Gurrado A., Inchingolo R., Ingels A., Ivatury R., Kashuk J. L., Khan J., Kirkpatrick A. W., Kim F. J., Kluger Y., Lakkis Z., Leppaniemi A., Maier R. V., Memeo R., Moore E. E., Ordonez C. A., Peitzman A. B., Pellino G., Picetti E., Pikoulis M., Pisano M., Podda M., Romeo O., Rosa F., Tan E., Ten Broek R. P., Testini M., Tian Wei Cheng B. A., Weber D., Sacco E., Sartelli M., Tonsi A., Dal Moro F., and Catena F.
Abstract: Iatrogenic urinary tract injury (IUTI) is a severe complication of emergency digestive surgery. It can lead to increased postoperative morbidity and mortality and have a long-term impact on the quality of life. The reported incidence of IUTIs varies greatly among the studies, ranging from 0.3 to 1.5%. Given the high volume of emergency digestive surgery performed worldwide, there is a need for well-defined and effective strategies to prevent and manage IUTIs. Currently, there is a lack of consensus regarding the prevention, detection, and management of IUTIs in the emergency setting. The present guidelines, promoted by the World Society of Emergency Surgery (WSES), were developed following a systematic review of the literature and an international expert panel discussion. The primary aim of these WSES guidelines is to provide evidence-based recommendations to support clinicians and surgeons in the prevention, detection, and management of IUTIs during emergency digestive surgery. The following key aspects were considered: (1) effectiveness of preventive interventions for IUTIs during emergency digestive surgery; (2) intra-operative detection of IUTIs and appropriate management strategies; (3) postoperative detection of IUTIs and appropriate management strategies and timing; and (4) effectiveness of antibiotic therapy (including type and duration) in case of IUTIs.
Published: 2023

3. WSES consensus guidelines on sigmoid volvulus management

Author: Tian, B, Vigutto, G, Tan, E, van Goor, H, Bendinelli, C, Abu-Zidan, F, Ivatury, R, Sakakushev, B, Di Carlo, I, Sganga, G, Maier, R, Coimbra, R, Leppaniemi, A, Litvin, A, Damaskos, D, Broek, R, Biffl, W, Di Saverio, S, De Simone, B, Ceresoli, M, Picetti, E, Galante, J, Tebala, G, Beka, S, Bonavina, L, Cui, Y, Khan, J, Cicuttin, E, Amico, F, Kenji, I, Hecker, A, Ansaloni, L, Sartelli, M, Moore, E, Kluger, Y, Testini, M, Weber, D, Agnoletti, V, Angelis, N, Coccolini, F, Sall, I, Catena, F, Tian B. W. C. A., Vigutto G., Tan E., van Goor H., Bendinelli C., Abu-Zidan F., Ivatury R., Sakakushev B., Di Carlo I., Sganga G., Maier R. V., Coimbra R., Leppaniemi A., Litvin A., Damaskos D., Broek R. T., Biffl W., Di Saverio S., De Simone B., Ceresoli M., Picetti E., Galante J., Tebala G. D., Beka S. G., Bonavina L., Cui Y., Khan J., Cicuttin E., Amico F., Kenji I., Hecker A., Ansaloni L., Sartelli M., Moore E. E., Kluger Y., Testini M., Weber D., Agnoletti V., Angelis N. D., Coccolini F., Sall I., Catena F., Tian, B, Vigutto, G, Tan, E, van Goor, H, Bendinelli, C, Abu-Zidan, F, Ivatury, R, Sakakushev, B, Di Carlo, I, Sganga, G, Maier, R, Coimbra, R, Leppaniemi, A, Litvin, A, Damaskos, D, Broek, R, Biffl, W, Di Saverio, S, De Simone, B, Ceresoli, M, Picetti, E, Galante, J, Tebala, G, Beka, S, Bonavina, L, Cui, Y, Khan, J, Cicuttin, E, Amico, F, Kenji, I, Hecker, A, Ansaloni, L, Sartelli, M, Moore, E, Kluger, Y, Testini, M, Weber, D, Agnoletti, V, Angelis, N, Coccolini, F, Sall, I, Catena, F, Tian B. W. C. A., Vigutto G., Tan E., van Goor H., Bendinelli C., Abu-Zidan F., Ivatury R., Sakakushev B., Di Carlo I., Sganga G., Maier R. V., Coimbra R., Leppaniemi A., Litvin A., Damaskos D., Broek R. T., Biffl W., Di Saverio S., De Simone B., Ceresoli M., Picetti E., Galante J., Tebala G. D., Beka S. G., Bonavina L., Cui Y., Khan J., Cicuttin E., Amico F., Kenji I., Hecker A., Ansaloni L., Sartelli M., Moore E. E., Kluger Y., Testini M., Weber D., Agnoletti V., Angelis N. D., Coccolini F., Sall I., and Catena F.
Abstract: Sigmoid volvulus is a common surgical emergency, especially in elderly patients. Patients can present with a wide range of clinical states: from asymptomatic, to frank peritonitis secondary to colonic perforation. These patients generally need urgent treatment, be it endoscopic decompression of the colon or an upfront colectomy. The World Society of Emergency Surgery united a worldwide group of international experts to review the current evidence and propose a consensus guidelines on the management of sigmoid volvulus.
Published: 2023

4. The new timing in acute care surgery (new TACS) classification: a WSES Delphi consensus study

Author: De Simone, B, Kluger, Y, Moore, E, Sartelli, M, Abu-Zidan, F, Coccolini, F, Ansaloni, L, Tebala, G, Di Saverio, S, Di Carlo, I, Sakakushev, B, Bonavina, L, Sugrue, M, Galante, J, Ivatury, R, Picetti, E, Chirica, M, Wani, I, Bala, M, Sall, I, Kirkpatrick, A, Shelat, V, Pikoulis, E, Leppäniemi, A, Tan, E, Broek, R, Gurmu Beka, S, Litvin, A, Chouillard, E, Coimbra, R, Cui, Y, De’ Angelis, N, Sganga, G, Stahel, P, Agnoletti, V, Rampini, A, Damaskos, D, Carcoforo, P, Biffl, W, Hecker, A, Di Salomone, S, Balogh, Z, Beka, S, Velmahos, G, Ceresoli, M, Chiara, O, Leppaniemi, A, Marzi, I, Inaba, K, Khokha, V, Reva, V, Khan, M, Toro, A, de’ Angelis, N, Malangoni, M, Scozzafava, E, Civil, I, Maier, R, Weber, D, Chiarugi, M, Soreide, K, Testini, M, Bravi, F, Catena, F, De Simone B., Kluger Y., Moore E. E., Sartelli M., Abu-Zidan F. M., Coccolini F., Ansaloni L., Tebala G. D., Di Saverio S., Di Carlo I., Sakakushev B. E., Bonavina L., Sugrue M., Galante J. M., Ivatury R., Picetti E., Chirica M., Wani I., Bala M., Sall I., Kirkpatrick A. W., Shelat V. G., Pikoulis E., Leppäniemi A., Tan E., Broek R. P. G. t., Gurmu Beka S., Litvin A., Chouillard E., Coimbra R., Cui Y., De’ Angelis N., Sganga G., Stahel P. F., Agnoletti V., Rampini A., Shelat V., Damaskos D., Carcoforo P., Biffl W. L., Hecker A., Kirkpatrick A., Di Salomone S., Balogh Z., Beka S. G., Broek R. T., Velmahos G., Sakakushev B., Ceresoli M., Chiara O., Stahel P., Leppaniemi A., Marzi I., Inaba K., Khokha V., Reva V., Khan M., Toro A., de’ Angelis N., Malangoni M., Scozzafava E., Civil I., Maier R., Weber D., Chiarugi M., Soreide K., Testini M., Bravi F., Maier R. V., Catena F., De Simone, B, Kluger, Y, Moore, E, Sartelli, M, Abu-Zidan, F, Coccolini, F, Ansaloni, L, Tebala, G, Di Saverio, S, Di Carlo, I, Sakakushev, B, Bonavina, L, Sugrue, M, Galante, J, Ivatury, R, Picetti, E, Chirica, M, Wani, I, Bala, M, Sall, I, Kirkpatrick, A, Shelat, V, Pikoulis, E, Leppäniemi, A, Tan, E, Broek, R, Gurmu Beka, S, Litvin, A, Chouillard, E, Coimbra, R, Cui, Y, De’ Angelis, N, Sganga, G, Stahel, P, Agnoletti, V, Rampini, A, Damaskos, D, Carcoforo, P, Biffl, W, Hecker, A, Di Salomone, S, Balogh, Z, Beka, S, Velmahos, G, Ceresoli, M, Chiara, O, Leppaniemi, A, Marzi, I, Inaba, K, Khokha, V, Reva, V, Khan, M, Toro, A, de’ Angelis, N, Malangoni, M, Scozzafava, E, Civil, I, Maier, R, Weber, D, Chiarugi, M, Soreide, K, Testini, M, Bravi, F, Catena, F, De Simone B., Kluger Y., Moore E. E., Sartelli M., Abu-Zidan F. M., Coccolini F., Ansaloni L., Tebala G. D., Di Saverio S., Di Carlo I., Sakakushev B. E., Bonavina L., Sugrue M., Galante J. M., Ivatury R., Picetti E., Chirica M., Wani I., Bala M., Sall I., Kirkpatrick A. W., Shelat V. G., Pikoulis E., Leppäniemi A., Tan E., Broek R. P. G. t., Gurmu Beka S., Litvin A., Chouillard E., Coimbra R., Cui Y., De’ Angelis N., Sganga G., Stahel P. F., Agnoletti V., Rampini A., Shelat V., Damaskos D., Carcoforo P., Biffl W. L., Hecker A., Kirkpatrick A., Di Salomone S., Balogh Z., Beka S. G., Broek R. T., Velmahos G., Sakakushev B., Ceresoli M., Chiara O., Stahel P., Leppaniemi A., Marzi I., Inaba K., Khokha V., Reva V., Khan M., Toro A., de’ Angelis N., Malangoni M., Scozzafava E., Civil I., Maier R., Weber D., Chiarugi M., Soreide K., Testini M., Bravi F., Maier R. V., and Catena F.
Abstract: Background: Timely access to the operating room for emergency general surgery (EGS) indications remains a challenge across the globe, largely driven by operating room availability and staffing constraints. The “timing in acute care surgery” (TACS) classification was previously published to introduce a new tool to triage the timely and appropriate access of EGS patients to the operating room. However, the clinical and operational effectiveness of the TACS classification has not been investigated in subsequent validation studies. This study aimed to improve the TACS classification and provide further consensus around the appropriate use of the new TACS classification through a standardized Delphi approach with international experts. Methods: This is a validation study of the new TACS by a selected international panel of experts using the Delphi method. The TACS questionnaire was designed as a web-based survey. The consensus agreement level was established to be ≥ 75%. The collective consensus agreement was defined as the sum of the percentage of the highest Likert scale levels (4–5) out of all participants. Surgical emergency diseases and correlated clinical scenarios were defined for each of the proposed classes. Subsequent rounds were carried out until a definitive level of consensus was reached. Frequencies and percentages were calculated to determine the degree of agreement for each surgical disease. Results: Four polling rounds were carried out. The new TACS classification provides 6 colour-code classes correlated to a precise timing to surgery, defined scenarios and surgical condition. The WHITE colour-code class was introduced to rapidly (within a week) reschedule cancelled or postponed surgical procedures. Haemodynamic stability is the main tool to stratify patients for immediate surgery or not in the presence of sepsis/septic shock. Fifty-one surgical diseases were included in the different colour-code classes of priority. Conclusion: The new TACS classificat
Published: 2023

5. The unrestricted global effort to complete the COOL trial

Author: Kirkpatrick, A, Coccolini, F, Tolonen, M, Minor, S, Catena, F, Gois, E, Doig, C, Hill, M, Ansaloni, L, Chiarugi, M, Tartaglia, D, Ioannidis, O, Sugrue, M, Colak, E, Hameed, S, Lampela, H, Agnoletti, V, Mckee, J, Garraway, N, Sartelli, M, Ball, C, Parry, N, Voght, K, Julien, L, Kroeker, J, Roberts, D, Faris, P, Tiruta, C, Moore, E, Ammons, L, Anestiadou, E, Bendinelli, C, Bouliaris, K, Carroll, R, Ceresoli, M, Favi, F, Gurrado, A, Rezende-Neto, J, Isik, A, Cremonini, C, Strambi, S, Koukoulis, G, Testini, M, Trpcic, S, Pasculli, A, Picariello, E, Abu-Zidan, F, Adeyeye, A, Augustin, G, Alconchel, F, Altinel, Y, Hernandez Amin, L, Aranda-Narvaez, J, Baraket, O, Biffl, W, Baiocchi, G, Bonavina, L, Brisinda, G, Cardinali, L, Celotti, A, Chaouch, M, Chiarello, M, Costa, G, De'Angelis, N, De Manzini, N, Delibegovic, S, Di Saverio, S, De Simone, B, Dubuisson, V, Fransvea, P, Garulli, G, Giordano, A, Gomes, C, Hayati, F, Huang, J, Ibrahim, A, Huei, T, Jailani, R, Khan, M, Luna, A, Malbrain, M, Marwah, S, Mcbeth, P, Mihailescu, A, Morello, A, Mulita, F, Murzi, V, Mohammad, A, Parmar, S, Pak, A, Wong, M, Pantalone, D, Podda, M, Puccioni, C, Rasa, K, Ren, J, Roscio, F, Gonzalez-Sanchez, A, Sganga, G, Scheiterle, M, Slavchev, M, Smirnov, D, Tosi, L, Trivedi, A, Vega, J, Waledziak, M, Xenaki, S, Winter, D, Wu, X, Zakaria, A, Zakaria, Z, Kirkpatrick A. W., Coccolini F., Tolonen M., Minor S., Catena F., Gois E., Doig C. J., Hill M. D., Ansaloni L., Chiarugi M., Tartaglia D., Ioannidis O., Sugrue M., Colak E., Hameed S. M., Lampela H., Agnoletti V., McKee J. L., Garraway N., Sartelli M., Ball C. G., Parry N. G., Voght K., Julien L., Kroeker J., Roberts D. J., Faris P., Tiruta C., Moore E. E., Ammons L. A., Anestiadou E., Bendinelli C., Bouliaris K., Carroll R., Ceresoli M., Favi F., Gurrado A., Rezende-Neto J., Isik A., Cremonini C., Strambi S., Koukoulis G., Testini M., Trpcic S., Pasculli A., Picariello E., Abu-Zidan F., Adeyeye A., Augustin G., Alconchel F., Altinel Y., Hernandez Amin L. A., Aranda-Narvaez J. M., Baraket O., Biffl W. L., Baiocchi G. L., Bonavina L., Brisinda G., Cardinali L., Celotti A., Chaouch M., Chiarello M., Costa G., de'Angelis N., De Manzini N., Delibegovic S., Di Saverio S., De Simone B., Dubuisson V., Fransvea P., Garulli G., Giordano A., Gomes C., Hayati F., Huang J., Ibrahim A. F., Huei T. J., Jailani R. F., Khan M., Luna A. P., Malbrain M. L. N. G., Marwah S., McBeth P., Mihailescu A., Morello A., Mulita F., Murzi V., Mohammad A. T., Parmar S., Pak A., Wong M. P. -K., Pantalone D., Podda M., Puccioni C., Rasa K., Ren J., Roscio F., Gonzalez-Sanchez A., Sganga G., Scheiterle M., Slavchev M., Smirnov D., Tosi L., Trivedi A., Vega J. A. G., Waledziak M., Xenaki S., Winter D., Wu X., Zakaria A. D., Zakaria Z., Kirkpatrick, A, Coccolini, F, Tolonen, M, Minor, S, Catena, F, Gois, E, Doig, C, Hill, M, Ansaloni, L, Chiarugi, M, Tartaglia, D, Ioannidis, O, Sugrue, M, Colak, E, Hameed, S, Lampela, H, Agnoletti, V, Mckee, J, Garraway, N, Sartelli, M, Ball, C, Parry, N, Voght, K, Julien, L, Kroeker, J, Roberts, D, Faris, P, Tiruta, C, Moore, E, Ammons, L, Anestiadou, E, Bendinelli, C, Bouliaris, K, Carroll, R, Ceresoli, M, Favi, F, Gurrado, A, Rezende-Neto, J, Isik, A, Cremonini, C, Strambi, S, Koukoulis, G, Testini, M, Trpcic, S, Pasculli, A, Picariello, E, Abu-Zidan, F, Adeyeye, A, Augustin, G, Alconchel, F, Altinel, Y, Hernandez Amin, L, Aranda-Narvaez, J, Baraket, O, Biffl, W, Baiocchi, G, Bonavina, L, Brisinda, G, Cardinali, L, Celotti, A, Chaouch, M, Chiarello, M, Costa, G, De'Angelis, N, De Manzini, N, Delibegovic, S, Di Saverio, S, De Simone, B, Dubuisson, V, Fransvea, P, Garulli, G, Giordano, A, Gomes, C, Hayati, F, Huang, J, Ibrahim, A, Huei, T, Jailani, R, Khan, M, Luna, A, Malbrain, M, Marwah, S, Mcbeth, P, Mihailescu, A, Morello, A, Mulita, F, Murzi, V, Mohammad, A, Parmar, S, Pak, A, Wong, M, Pantalone, D, Podda, M, Puccioni, C, Rasa, K, Ren, J, Roscio, F, Gonzalez-Sanchez, A, Sganga, G, Scheiterle, M, Slavchev, M, Smirnov, D, Tosi, L, Trivedi, A, Vega, J, Waledziak, M, Xenaki, S, Winter, D, Wu, X, Zakaria, A, Zakaria, Z, Kirkpatrick A. W., Coccolini F., Tolonen M., Minor S., Catena F., Gois E., Doig C. J., Hill M. D., Ansaloni L., Chiarugi M., Tartaglia D., Ioannidis O., Sugrue M., Colak E., Hameed S. M., Lampela H., Agnoletti V., McKee J. L., Garraway N., Sartelli M., Ball C. G., Parry N. G., Voght K., Julien L., Kroeker J., Roberts D. J., Faris P., Tiruta C., Moore E. E., Ammons L. A., Anestiadou E., Bendinelli C., Bouliaris K., Carroll R., Ceresoli M., Favi F., Gurrado A., Rezende-Neto J., Isik A., Cremonini C., Strambi S., Koukoulis G., Testini M., Trpcic S., Pasculli A., Picariello E., Abu-Zidan F., Adeyeye A., Augustin G., Alconchel F., Altinel Y., Hernandez Amin L. A., Aranda-Narvaez J. M., Baraket O., Biffl W. L., Baiocchi G. L., Bonavina L., Brisinda G., Cardinali L., Celotti A., Chaouch M., Chiarello M., Costa G., de'Angelis N., De Manzini N., Delibegovic S., Di Saverio S., De Simone B., Dubuisson V., Fransvea P., Garulli G., Giordano A., Gomes C., Hayati F., Huang J., Ibrahim A. F., Huei T. J., Jailani R. F., Khan M., Luna A. P., Malbrain M. L. N. G., Marwah S., McBeth P., Mihailescu A., Morello A., Mulita F., Murzi V., Mohammad A. T., Parmar S., Pak A., Wong M. P. -K., Pantalone D., Podda M., Puccioni C., Rasa K., Ren J., Roscio F., Gonzalez-Sanchez A., Sganga G., Scheiterle M., Slavchev M., Smirnov D., Tosi L., Trivedi A., Vega J. A. G., Waledziak M., Xenaki S., Winter D., Wu X., Zakaria A. D., and Zakaria Z.
Abstract: Background: Severe complicated intra-abdominal sepsis (SCIAS) has an increasing incidence with mortality rates over 80% in some settings. Mortality typically results from disruption of the gastrointestinal tract, progressive and self-perpetuating bio-mediator generation, systemic inflammation, and multiple organ failure. A further therapeutic option may be open abdomen (OA) management with negative peritoneal pressure therapy (NPPT) to remove inflammatory ascites and attenuate the systemic damage from SCIAS, although there are definite risks of leaving the abdomen open whenever it might possibly be closed. This potential therapeutic paradigm is the rationale being assessed in the Closed Or Open after Laparotomy (COOL trial) (https://clinicaltrials.gov/ct2/show/NCT03163095). Initially, the COOL trial received Industry sponsorship; however, this funding mandated the use of a specific trademarked and expensive NPPT device in half of the patients allocated to the intervention (open) arm. In August 2022, the 3 M/Acelity Corporation without consultation but within the terms of the contract canceled the financial support of the trial. Although creating financial difficulty, there is now no restriction on specific NPPT devices and removing a cost-prohibitive intervention creates an opportunity to expand the COOL trial to a truly global basis. This document describes the evolution of the COOL trial, with a focus on future opportunities for global growth of the study. Methods: The COOL trial is the largest prospective randomized controlled trial examining the random allocation of SCIAS patients intra-operatively to either formal closure of the fascia or the use of the OA with an application of an NPPT dressing. Patients are eligible if they have free uncontained intraperitoneal contamination and physiologic derangements exemplified by septic shock OR severely adverse predicted clinical outcomes. The primary outcome is intended to definitively inform global practice by co
Published: 2023

6. WSES consensus guidelines on sigmoid volvulus management

Author: Tian, B.W.C.A., Vigutto, G., Tan, E.C.T.H., Goor, H. van, Bendinelli, C., Abu-Zidan, F., Ivatury, R., Sakakushev, B., Carlo, I. Di, Sganga, G., Maier, R.V., Coimbra, R., Leppäniemi, A., Litvin, A., Damaskos, D., Broek, R.P.G ten, Biffl, W., Saverio, S. Di, Simone, B. De, Ceresoli, M., Picetti, E., Galante, J., Tebala, G.D., Beka, S.G., Bonavina, L., Cui, Y., Khan, J., Cicuttin, E., Amico, F., Kenji, I., Hecker, A., Ansaloni, L., Sartelli, M., Moore, E.E., Kluger, Y., Testini, M., Weber, D., Agnoletti, V., Angelis, N.D., Coccolini, F., Sall, I., Catena, F., Tian, B, Vigutto, G, Tan, E, van Goor, H, Bendinelli, C, Abu-Zidan, F, Ivatury, R, Sakakushev, B, Di Carlo, I, Sganga, G, Maier, R, Coimbra, R, Leppaniemi, A, Litvin, A, Damaskos, D, Broek, R, Biffl, W, Di Saverio, S, De Simone, B, Ceresoli, M, Picetti, E, Galante, J, Tebala, G, Beka, S, Bonavina, L, Cui, Y, Khan, J, Cicuttin, E, Amico, F, Kenji, I, Hecker, A, Ansaloni, L, Sartelli, M, Moore, E, Kluger, Y, Testini, M, Weber, D, Agnoletti, V, Angelis, N, Coccolini, F, Sall, I, and Catena, F
Subjects: Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10], Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], All institutes and research themes of the Radboud University Medical Center, Emergency Medicine, sigmoid volvolus, Surgery
Abstract: Contains fulltext : 293045.pdf (Publisher’s version ) (Open Access) Sigmoid volvulus is a common surgical emergency, especially in elderly patients. Patients can present with a wide range of clinical states: from asymptomatic, to frank peritonitis secondary to colonic perforation. These patients generally need urgent treatment, be it endoscopic decompression of the colon or an upfront colectomy. The World Society of Emergency Surgery united a worldwide group of international experts to review the current evidence and propose a consensus guidelines on the management of sigmoid volvulus.
Published: 2023

7. The new timing in acute care surgery (new TACS) classification: a WSES Delphi consensus study

Author: De Simone B., Kluger Y., Moore E. E., Sartelli M., Abu-Zidan F. M., Coccolini F., Ansaloni L., Tebala G. D., Di Saverio S., Di Carlo I., Sakakushev B. E., Bonavina L., Sugrue M., Galante J. M., Ivatury R., Picetti E., Chirica M., Wani I., Bala M., Sall I., Kirkpatrick A. W., Shelat V. G., Pikoulis E., Leppäniemi A., Tan E., Broek R. P. G. t., Gurmu Beka S., Litvin A., Chouillard E., Coimbra R., Cui Y., De’ Angelis N., Sganga G., Stahel P. F., Agnoletti V., Rampini A., Shelat V., Damaskos D., Carcoforo P., Biffl W. L., Hecker A., Kirkpatrick A., Di Salomone S., Balogh Z., Beka S. G., Broek R. T., Velmahos G., Sakakushev B., Ceresoli M., Chiara O., Stahel P., Leppaniemi A., Marzi I., Inaba K., Khokha V., Reva V., Khan M., Toro A., de’ Angelis N., Malangoni M., Scozzafava E., Civil I., Maier R., Weber D., Chiarugi M., Soreide K., Testini M., Bravi F., Maier R. V., Catena F., De Simone, B, Kluger, Y, Moore, E, Sartelli, M, Abu-Zidan, F, Coccolini, F, Ansaloni, L, Tebala, G, Di Saverio, S, Di Carlo, I, Sakakushev, B, Bonavina, L, Sugrue, M, Galante, J, Ivatury, R, Picetti, E, Chirica, M, Wani, I, Bala, M, Sall, I, Kirkpatrick, A, Shelat, V, Pikoulis, E, Leppäniemi, A, Tan, E, Broek, R, Gurmu Beka, S, Litvin, A, Chouillard, E, Coimbra, R, Cui, Y, De’ Angelis, N, Sganga, G, Stahel, P, Agnoletti, V, Rampini, A, Damaskos, D, Carcoforo, P, Biffl, W, Hecker, A, Di Salomone, S, Balogh, Z, Beka, S, Velmahos, G, Ceresoli, M, Chiara, O, Leppaniemi, A, Marzi, I, Inaba, K, Khokha, V, Reva, V, Khan, M, Toro, A, de’ Angelis, N, Malangoni, M, Scozzafava, E, Civil, I, Maier, R, Weber, D, Chiarugi, M, Soreide, K, Testini, M, Bravi, F, and Catena, F
Subjects: Healthcare system, Delay in surgery, Operating room management, Delphi method, Emergency surgery, Priority, Time to surgery, Timing in acute care surgery (TACS), Triage, Classification
Abstract: Background: Timely access to the operating room for emergency general surgery (EGS) indications remains a challenge across the globe, largely driven by operating room availability and staffing constraints. The “timing in acute care surgery” (TACS) classification was previously published to introduce a new tool to triage the timely and appropriate access of EGS patients to the operating room. However, the clinical and operational effectiveness of the TACS classification has not been investigated in subsequent validation studies. This study aimed to improve the TACS classification and provide further consensus around the appropriate use of the new TACS classification through a standardized Delphi approach with international experts. Methods: This is a validation study of the new TACS by a selected international panel of experts using the Delphi method. The TACS questionnaire was designed as a web-based survey. The consensus agreement level was established to be ≥ 75%. The collective consensus agreement was defined as the sum of the percentage of the highest Likert scale levels (4–5) out of all participants. Surgical emergency diseases and correlated clinical scenarios were defined for each of the proposed classes. Subsequent rounds were carried out until a definitive level of consensus was reached. Frequencies and percentages were calculated to determine the degree of agreement for each surgical disease. Results: Four polling rounds were carried out. The new TACS classification provides 6 colour-code classes correlated to a precise timing to surgery, defined scenarios and surgical condition. The WHITE colour-code class was introduced to rapidly (within a week) reschedule cancelled or postponed surgical procedures. Haemodynamic stability is the main tool to stratify patients for immediate surgery or not in the presence of sepsis/septic shock. Fifty-one surgical diseases were included in the different colour-code classes of priority. Conclusion: The new TACS classification is a comprehensive, simple, clear and reproducible triage system which can be used to assess the severity of the patient and the surgical disease, to reduce the time to access to the operating room, and to manage the emergency surgical patients within a “safe” timeframe. By including well-defined surgical diseases in the different colour-code classes of priority, validated through a Delphi consensus, the new TACS improves communication among surgeons, between surgeons and anaesthesiologists and decreases conflicts and waste and waiting time in accessing the operating room for emergency surgical patients.
Published: 2023

8. Current practice on the use of prophylactic drain after gastrectomy in Italy: the Abdominal Drain in Gastrectomy (ADiGe) survey

Author: Mengardo, V, Weindelmayer, J, Veltri, A, Giacopuzzi, S, Torroni, L, de Manzoni, G, Agresta, F, Alfieri, R, Alfieri, S, Antonacci, N, Baiocchi, G, Bencini, L, Bencivenga, M, Benedetti, M, Berselli, M, Biondi, A, Capolupo, G, Carboni, F, Casadei, R, Casella, F, Catarci, M, Cerri, P, Chiari, D, Cocozza, E, Colombo, G, Cozzaglio, L, Dalmonte, G, Degiuli, M, De Luca, M, De Luca, R, De Manzini, N, De Pasqual, C, De Pascale, S, De Ruvo, N, Di Cosmo, M, Di Leo, A, Di Paola, M, Elio, A, Ferrara, F, Ferrari, G, Fiscon, V, Fumagalli, U, Garulli, G, Gennai, A, Gentile, I, Germani, P, Gualtierotti, M, Guerini, F, Gurrado, A, Inama, M, La Torre, F, Laterza, E, Losurdo, P, Macri, A, Marano, A, Marano, L, Marchesi, F, Marino, F, Massani, M, Menghi, R, Milone, M, Molfino, S, Montuori, M, Moretto, G, Morgagni, P, Morpurgo, E, Abdallah, M, Nespoli, L, Olmi, S, Palaia, R, Pallabazer, G, Parise, P, Pasculli, A, Pericoli Ridolfini, M, Pesce, A, Pinotti, E, Pisano, M, Poiasina, E, Postiglione, V, Rausei, S, Rella, A, Rosa, F, Rosati, R, Rossi, G, Rossit, L, Rovatti, M, Ruspi, L, Sacco, L, Saladino, E, Sansonetti, A, Sartori, A, Scaglione, D, Scaringi, S, Schoenthaler, C, Sena, G, Simone, M, Solaini, L, Strignano, P, Tartaglia, N, Testa, S, Testini, M, Tiberio, G, Treppiedi, E, Vagliasindi, A, Valmasoni, M, Vigano, J, Zanchettin, G, Zanoni, A, Zardini, C, Zerbinati, A, Mengardo V., Weindelmayer J., Veltri A., Giacopuzzi S., Torroni L., de Manzoni G., Agresta F., Alfieri R., Alfieri S., Antonacci N., Baiocchi G. L., Bencini L., Bencivenga M., Benedetti M., Berselli M., Biondi A., Capolupo G. T., Carboni F., Casadei R., Casella F., Catarci M., Cerri P., Chiari D., Cocozza E., Colombo G., Cozzaglio L., Dalmonte G., Degiuli M., De Luca M., De Luca R., De Manzini N., De Pasqual C. A., De Pascale S., De Ruvo N., Di Cosmo M., Di Leo A., Di Paola M., Elio A., Ferrara F., Ferrari G., Fiscon V., Fumagalli U., Garulli G., Gennai A., Gentile I., Germani P., Gualtierotti M., Guerini F., Gurrado A., Inama M., La Torre F., Laterza E., Losurdo P., Macri A., Marano A., Marano L., Marchesi F., Marino F., Massani M., Menghi R., Milone M., Molfino S., Montuori M., Moretto G., Morgagni P., Morpurgo E., Abdallah M., Nespoli L., Olmi S., Palaia R., Pallabazer G., Parise P., Pasculli A., Pericoli Ridolfini M., Pesce A., Pinotti E., Pisano M., Poiasina E., Postiglione V., Rausei S., Rella A., Rosa F., Rosati R., Rossi G., Rossit L., Rovatti M., Ruspi L., Sacco L., Saladino E., Sansonetti A., Sartori A., Scaglione D., Scaringi S., Schoenthaler C., Sena G., Simone M., Solaini L., Strignano P., Tartaglia N., Testa S., Testini M., Tiberio G. A. M., Treppiedi E., Vagliasindi A., Valmasoni M., Vigano J., Zanchettin G., Zanoni A., Zardini C., Zerbinati A., Mengardo, V, Weindelmayer, J, Veltri, A, Giacopuzzi, S, Torroni, L, de Manzoni, G, Agresta, F, Alfieri, R, Alfieri, S, Antonacci, N, Baiocchi, G, Bencini, L, Bencivenga, M, Benedetti, M, Berselli, M, Biondi, A, Capolupo, G, Carboni, F, Casadei, R, Casella, F, Catarci, M, Cerri, P, Chiari, D, Cocozza, E, Colombo, G, Cozzaglio, L, Dalmonte, G, Degiuli, M, De Luca, M, De Luca, R, De Manzini, N, De Pasqual, C, De Pascale, S, De Ruvo, N, Di Cosmo, M, Di Leo, A, Di Paola, M, Elio, A, Ferrara, F, Ferrari, G, Fiscon, V, Fumagalli, U, Garulli, G, Gennai, A, Gentile, I, Germani, P, Gualtierotti, M, Guerini, F, Gurrado, A, Inama, M, La Torre, F, Laterza, E, Losurdo, P, Macri, A, Marano, A, Marano, L, Marchesi, F, Marino, F, Massani, M, Menghi, R, Milone, M, Molfino, S, Montuori, M, Moretto, G, Morgagni, P, Morpurgo, E, Abdallah, M, Nespoli, L, Olmi, S, Palaia, R, Pallabazer, G, Parise, P, Pasculli, A, Pericoli Ridolfini, M, Pesce, A, Pinotti, E, Pisano, M, Poiasina, E, Postiglione, V, Rausei, S, Rella, A, Rosa, F, Rosati, R, Rossi, G, Rossit, L, Rovatti, M, Ruspi, L, Sacco, L, Saladino, E, Sansonetti, A, Sartori, A, Scaglione, D, Scaringi, S, Schoenthaler, C, Sena, G, Simone, M, Solaini, L, Strignano, P, Tartaglia, N, Testa, S, Testini, M, Tiberio, G, Treppiedi, E, Vagliasindi, A, Valmasoni, M, Vigano, J, Zanchettin, G, Zanoni, A, Zardini, C, Zerbinati, A, Mengardo V., Weindelmayer J., Veltri A., Giacopuzzi S., Torroni L., de Manzoni G., Agresta F., Alfieri R., Alfieri S., Antonacci N., Baiocchi G. L., Bencini L., Bencivenga M., Benedetti M., Berselli M., Biondi A., Capolupo G. T., Carboni F., Casadei R., Casella F., Catarci M., Cerri P., Chiari D., Cocozza E., Colombo G., Cozzaglio L., Dalmonte G., Degiuli M., De Luca M., De Luca R., De Manzini N., De Pasqual C. A., De Pascale S., De Ruvo N., Di Cosmo M., Di Leo A., Di Paola M., Elio A., Ferrara F., Ferrari G., Fiscon V., Fumagalli U., Garulli G., Gennai A., Gentile I., Germani P., Gualtierotti M., Guerini F., Gurrado A., Inama M., La Torre F., Laterza E., Losurdo P., Macri A., Marano A., Marano L., Marchesi F., Marino F., Massani M., Menghi R., Milone M., Molfino S., Montuori M., Moretto G., Morgagni P., Morpurgo E., Abdallah M., Nespoli L., Olmi S., Palaia R., Pallabazer G., Parise P., Pasculli A., Pericoli Ridolfini M., Pesce A., Pinotti E., Pisano M., Poiasina E., Postiglione V., Rausei S., Rella A., Rosa F., Rosati R., Rossi G., Rossit L., Rovatti M., Ruspi L., Sacco L., Saladino E., Sansonetti A., Sartori A., Scaglione D., Scaringi S., Schoenthaler C., Sena G., Simone M., Solaini L., Strignano P., Tartaglia N., Testa S., Testini M., Tiberio G. A. M., Treppiedi E., Vagliasindi A., Valmasoni M., Vigano J., Zanchettin G., Zanoni A., Zardini C., and Zerbinati A.
Abstract: Evidence against the use of prophylactic drain after gastrectomy are increasing and ERAS guidelines suggest the benefit of drain avoidance. Nevertheless, it is unclear whether this practice is still widespread. We conducted a survey among Italian surgeons through the Italian Gastric Cancer Research Group and the Polispecialistic Society of Young Surgeons, aiming to understand the current use of prophylactic drain. A 28-item questionnaire-based survey was developed to analyze the current practice and the individual opinion about the use of prophylactic drain after gastrectomy. Groups based on age, experience and unit volume were separately analyzed. Response of 104 surgeons from 73 surgical units were collected. A standardized ERAS protocol for gastrectomy was applied by 42% of the respondents. Most of the surgeons, regardless of age, experience, or unit volume, declared to routinely place one or more drain after gastrectomy. Only 2 (1.9%) and 7 surgeons (6.7%) belonging to high volume units, do not routinely place drains after total and subtotal gastrectomy, respectively. More than 60% of the participants remove the drain on postoperative day 4–6 after performing an assessment of the anastomosis integrity. Interestingly, less than half of the surgeons believe that drain is the main tool for leak management, and this percentage further drops among younger surgeons. On the other hand, drain’s role seems to be more defined for duodenal stump leak treatment, with almost 50% of the surgeons recognizing its importance. Routine use of prophylactic drain after gastrectomy is still a widespread practice even if younger surgeons are more persuaded that it could not be advantageous.
Published: 2022

9. P191 Skin-sparing or nipple-sparing mastectomy with one-stage or two-stage reconstruction: analysis of early outcomes and patient’s satisfaction

Author: Gurrado, A., primary, Pasculli, A., additional, Maruccia, M., additional, Elia, R., additional, Moschetta, M., additional, Telegrafo, M., additional, Lavermicocca, W., additional, Poli, E., additional, Sgaramella, L.I., additional, De Luca, G.M., additional, Prete, F.P., additional, Giudice, G., additional, and Testini, M., additional
Published: 2023
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10. The new timing in acute care surgery (new TACS) classification: a WSES Delphi consensus study.

Author: Simone, B. De, Kluger, Y., Moore, E.E., Sartelli, M., Abu-Zidan, F.M., Coccolini, F., Ansaloni, L., Tebala, G.D., Saverio, S. Di, Carlo, I. Di, Sakakushev, B.E., Bonavina, L., Sugrue, M., Galante, J.M., Ivatury, R., Picetti, E., Chirica, M., Wani, I., Bala, M., Sall, I., Kirkpatrick, A.W., Shelat, V.G., Pikoulis, E., Leppäniemi, A., Tan, E., Broek, R.P.G ten, Gurmu Beka, S., Litvin, A., Chouillard, E., Coimbra, R., Cui, Y., De' Angelis, N., Sganga, G., Stahel, P.F., Agnoletti, V., Rampini, A., Testini, M., Bravi, F., Maier, R.V., Biffl, W.L., Catena, F., Simone, B. De, Kluger, Y., Moore, E.E., Sartelli, M., Abu-Zidan, F.M., Coccolini, F., Ansaloni, L., Tebala, G.D., Saverio, S. Di, Carlo, I. Di, Sakakushev, B.E., Bonavina, L., Sugrue, M., Galante, J.M., Ivatury, R., Picetti, E., Chirica, M., Wani, I., Bala, M., Sall, I., Kirkpatrick, A.W., Shelat, V.G., Pikoulis, E., Leppäniemi, A., Tan, E., Broek, R.P.G ten, Gurmu Beka, S., Litvin, A., Chouillard, E., Coimbra, R., Cui, Y., De' Angelis, N., Sganga, G., Stahel, P.F., Agnoletti, V., Rampini, A., Testini, M., Bravi, F., Maier, R.V., Biffl, W.L., and Catena, F.
Abstract: Item does not contain fulltext, BACKGROUND: Timely access to the operating room for emergency general surgery (EGS) indications remains a challenge across the globe, largely driven by operating room availability and staffing constraints. The "timing in acute care surgery" (TACS) classification was previously published to introduce a new tool to triage the timely and appropriate access of EGS patients to the operating room. However, the clinical and operational effectiveness of the TACS classification has not been investigated in subsequent validation studies. This study aimed to improve the TACS classification and provide further consensus around the appropriate use of the new TACS classification through a standardized Delphi approach with international experts. METHODS: This is a validation study of the new TACS by a selected international panel of experts using the Delphi method. The TACS questionnaire was designed as a web-based survey. The consensus agreement level was established to be ≥ 75%. The collective consensus agreement was defined as the sum of the percentage of the highest Likert scale levels (4-5) out of all participants. Surgical emergency diseases and correlated clinical scenarios were defined for each of the proposed classes. Subsequent rounds were carried out until a definitive level of consensus was reached. Frequencies and percentages were calculated to determine the degree of agreement for each surgical disease. RESULTS: Four polling rounds were carried out. The new TACS classification provides 6 colour-code classes correlated to a precise timing to surgery, defined scenarios and surgical condition. The WHITE colour-code class was introduced to rapidly (within a week) reschedule cancelled or postponed surgical procedures. Haemodynamic stability is the main tool to stratify patients for immediate surgery or not in the presence of sepsis/septic shock. Fifty-one surgical diseases were included in the different colour-code classes of priority. CONCLUSION: The new TACS classificat
Published: 2023

11. 2023 WSES guidelines for the prevention, detection, and management of iatrogenic urinary tract injuries (IUTIs) during emergency digestive surgery.

Author: De'Angelis, N., Schena, C.A., Marchegiani, F., Reitano, E., Simone, B. De, Wong, G.Y.M., Martínez-Pérez, A., Abu-Zidan, F.M., Agnoletti, V., Aisoni, F., Ammendola, M., Ansaloni, L., Bala, M., Biffl, W., Ceccarelli, G., Ceresoli, M., Chiara, O., Chiarugi, M., Cimbanassi, S., Coccolini, F., Coimbra, R., Saverio, S. Di, Diana, M., oguardi Burgio, M. Di, Fraga, G., Gavriilidis, P., Gurrado, A., Inchingolo, R., Ingels, A., Ivatury, R., Kashuk, J.L., Khan, J., Kirkpatrick, A.W., Kim, F.J., Kluger, Y., Lakkis, Z., Leppäniemi, A., Maier, R.V., Memeo, R., Moore, E.E., Ordoñez, C.A., Peitzman, A.B., Pellino, G., Picetti, E., Pikoulis, M., Pisano, M., Podda, M., Romeo, O., Rosa, F., Tan, E.C.T.H., Broek, R.P. ten, Testini, M., Tian Wei Cheng, B.A., Weber, D., Sacco, E., Sartelli, M., Tonsi, A., Moro, F. Dal, Catena, F., De'Angelis, N., Schena, C.A., Marchegiani, F., Reitano, E., Simone, B. De, Wong, G.Y.M., Martínez-Pérez, A., Abu-Zidan, F.M., Agnoletti, V., Aisoni, F., Ammendola, M., Ansaloni, L., Bala, M., Biffl, W., Ceccarelli, G., Ceresoli, M., Chiara, O., Chiarugi, M., Cimbanassi, S., Coccolini, F., Coimbra, R., Saverio, S. Di, Diana, M., oguardi Burgio, M. Di, Fraga, G., Gavriilidis, P., Gurrado, A., Inchingolo, R., Ingels, A., Ivatury, R., Kashuk, J.L., Khan, J., Kirkpatrick, A.W., Kim, F.J., Kluger, Y., Lakkis, Z., Leppäniemi, A., Maier, R.V., Memeo, R., Moore, E.E., Ordoñez, C.A., Peitzman, A.B., Pellino, G., Picetti, E., Pikoulis, M., Pisano, M., Podda, M., Romeo, O., Rosa, F., Tan, E.C.T.H., Broek, R.P. ten, Testini, M., Tian Wei Cheng, B.A., Weber, D., Sacco, E., Sartelli, M., Tonsi, A., Moro, F. Dal, and Catena, F.
Abstract: Contains fulltext : 296327.pdf (Publisher’s version ) (Open Access), Iatrogenic urinary tract injury (IUTI) is a severe complication of emergency digestive surgery. It can lead to increased postoperative morbidity and mortality and have a long-term impact on the quality of life. The reported incidence of IUTIs varies greatly among the studies, ranging from 0.3 to 1.5%. Given the high volume of emergency digestive surgery performed worldwide, there is a need for well-defined and effective strategies to prevent and manage IUTIs. Currently, there is a lack of consensus regarding the prevention, detection, and management of IUTIs in the emergency setting. The present guidelines, promoted by the World Society of Emergency Surgery (WSES), were developed following a systematic review of the literature and an international expert panel discussion. The primary aim of these WSES guidelines is to provide evidence-based recommendations to support clinicians and surgeons in the prevention, detection, and management of IUTIs during emergency digestive surgery. The following key aspects were considered: (1) effectiveness of preventive interventions for IUTIs during emergency digestive surgery; (2) intra-operative detection of IUTIs and appropriate management strategies; (3) postoperative detection of IUTIs and appropriate management strategies and timing; and (4) effectiveness of antibiotic therapy (including type and duration) in case of IUTIs.
Published: 2023

12. Cesena guidelines: WSES consensus statement on laparoscopic-first approach to general surgery emergencies and abdominal trauma.

Author: Sermonesi, G., Tian, B.W.C.A., Vallicelli, C., Abu-Zidan, F.M., Damaskos, D., Kelly, M.D., Leppäniemi, A., Galante, J.M., Tan, E.C.T.H., Kirkpatrick, A.W., Khokha, V., Romeo, O.M., Chirica, M., Pikoulis, M., Litvin, A., Shelat, V.G., Sakakushev, B., Wani, I., Sall, I., Fugazzola, P., Cicuttin, E., Toro, A., Amico, F., Mas, F.D., Simone, B. De, Sugrue, M., Bonavina, L., Campanelli, G., Carcoforo, P., Cobianchi, L., Coccolini, F., Chiarugi, M., Carlo, I. Di, Saverio, S. Di, Podda, M., Pisano, M., Sartelli, M., Testini, M., Fette, A., Rizoli, S., Picetti, E., Weber, D., Latifi, R., Kluger, Y., Balogh, Z.J., Biffl, W., Jeekel, H., Civil, I., Hecker, A., Ansaloni, L., Bravi, F., Agnoletti, V., Beka, S.G., Moore, E.E., Catena, F., Sermonesi, G., Tian, B.W.C.A., Vallicelli, C., Abu-Zidan, F.M., Damaskos, D., Kelly, M.D., Leppäniemi, A., Galante, J.M., Tan, E.C.T.H., Kirkpatrick, A.W., Khokha, V., Romeo, O.M., Chirica, M., Pikoulis, M., Litvin, A., Shelat, V.G., Sakakushev, B., Wani, I., Sall, I., Fugazzola, P., Cicuttin, E., Toro, A., Amico, F., Mas, F.D., Simone, B. De, Sugrue, M., Bonavina, L., Campanelli, G., Carcoforo, P., Cobianchi, L., Coccolini, F., Chiarugi, M., Carlo, I. Di, Saverio, S. Di, Podda, M., Pisano, M., Sartelli, M., Testini, M., Fette, A., Rizoli, S., Picetti, E., Weber, D., Latifi, R., Kluger, Y., Balogh, Z.J., Biffl, W., Jeekel, H., Civil, I., Hecker, A., Ansaloni, L., Bravi, F., Agnoletti, V., Beka, S.G., Moore, E.E., and Catena, F.
Abstract: Contains fulltext : 300061.pdf (Publisher’s version ) (Open Access), BACKGROUND: Laparoscopy is widely adopted across nearly all surgical subspecialties in the elective setting. Initially finding indication in minor abdominal emergencies, it has gradually become the standard approach in the majority of elective general surgery procedures. Despite many technological advances and increasing acceptance, the laparoscopic approach remains underutilized in emergency general surgery and in abdominal trauma. Emergency laparotomy continues to carry a high morbidity and mortality. In recent years, there has been a growing interest from emergency and trauma surgeons in adopting minimally invasive surgery approaches in the acute surgical setting. The present position paper, supported by the World Society of Emergency Surgery (WSES), aims to provide a review of the literature to reach a consensus on the indications and benefits of a laparoscopic-first approach in patients requiring emergency abdominal surgery for general surgery emergencies or abdominal trauma. METHODS: This position paper was developed according to the WSES methodology. A steering committee performed the literature review and drafted the position paper. An international panel of 54 experts then critically revised the manuscript and discussed it in detail, to develop a consensus on a position statement. RESULTS: A total of 323 studies (systematic review and meta-analysis, randomized clinical trial, retrospective comparative cohort studies, case series) have been selected from an initial pool of 7409 studies. Evidence demonstrates several benefits of the laparoscopic approach in stable patients undergoing emergency abdominal surgery for general surgical emergencies or abdominal trauma. The selection of a stable patient seems to be of paramount importance for a safe adoption of a laparoscopic approach. In hemodynamically stable patients, the laparoscopic approach was found to be safe, feasible and effective as a therapeutic tool or helpful to identify further management steps and n
Published: 2023

13. Surgical management of the pancreatic stump following pancreato-duodenectomy

Author: Testini, M., Piccinni, G., Lissidini, G., Gurrado, A., Tedeschi, M., Franco, I.F., Di Meo, G., Pasculli, A., De Luca, G.M., Ribezzi, M., and Falconi, M.
Published: 2016
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14. Comment traiter le moignon pancréatique après duodénopancréatectomie céphalique

Author: Testini, M., Piccinni, G., Lissidini, G., Gurrado, A., Tedeschi, M., Franco, I.F., Di Meo, G., Pasculli, A., De Luca, G.M., Ribezzi, M., and Falconi, M.
Published: 2016
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15. Recurrent laryngeal nerve palsy and substernal goiter. An Italian multicenter study

Author: Testini, M., Gurrado, A., Bellantone, R., Brazzarola, P., Cortese, R., De Toma, G., Fabiola Franco, I., Lissidini, G., Pio Lombardi, C., Minerva, F., Di Meo, G., Pasculli, A., Piccinni, G., and Rosato, L.
Published: 2014
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16. Paralysie récurrentielle et goitre sous-sternal : une étude multicentrique italienne

Author: Testini, M., Gurrado, A., Bellantone, R., Brazzarola, P., Cortese, R., De Toma, G., Franco, I.F., Lissidini, G., Lombardi, C. Pio, Minerva, F., Di Meo, G., Pasculli, A., Piccinni, G., and Rosato, L.
Published: 2014
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17. Anorectal emergencies: WSES-AAST guidelines

Author: Tarasconi, A, Perrone, G, Davies, J, Coimbra, R, Moore, E, Azzaroli, F, Abongwa, H, De Simone, B, Gallo, G, Rossi, G, Abu-Zidan, F, Agnoletti, V, De'Angelis, G, De'Angelis, N, Ansaloni, L, Baiocchi, G, Carcoforo, P, Ceresoli, M, Chichom-Mefire, A, Di Saverio, S, Gaiani, F, Giuffrida, M, Hecker, A, Inaba, K, Kelly, M, Kirkpatrick, A, Kluger, Y, Leppaniemi, A, Litvin, A, Ordonez, C, Pattonieri, V, Peitzman, A, Pikoulis, M, Sakakushev, B, Sartelli, M, Shelat, V, Tan, E, Testini, M, Velmahos, G, Wani, I, Weber, D, Biffl, W, Coccolini, F, Catena, F, Tarasconi A., Perrone G., Davies J., Coimbra R., Moore E., Azzaroli F., Abongwa H., De Simone B., Gallo G., Rossi G., Abu-Zidan F., Agnoletti V., de'Angelis G., de'Angelis N., Ansaloni L., Baiocchi G. L., Carcoforo P., Ceresoli M., Chichom-Mefire A., Di Saverio S., Gaiani F., Giuffrida M., Hecker A., Inaba K., Kelly M., Kirkpatrick A., Kluger Y., Leppaniemi A., Litvin A., Ordonez C., Pattonieri V., Peitzman A., Pikoulis M., Sakakushev B., Sartelli M., Shelat V., Tan E., Testini M., Velmahos G., Wani I., Weber D., Biffl W., Coccolini F., Catena F., Tarasconi, A, Perrone, G, Davies, J, Coimbra, R, Moore, E, Azzaroli, F, Abongwa, H, De Simone, B, Gallo, G, Rossi, G, Abu-Zidan, F, Agnoletti, V, De'Angelis, G, De'Angelis, N, Ansaloni, L, Baiocchi, G, Carcoforo, P, Ceresoli, M, Chichom-Mefire, A, Di Saverio, S, Gaiani, F, Giuffrida, M, Hecker, A, Inaba, K, Kelly, M, Kirkpatrick, A, Kluger, Y, Leppaniemi, A, Litvin, A, Ordonez, C, Pattonieri, V, Peitzman, A, Pikoulis, M, Sakakushev, B, Sartelli, M, Shelat, V, Tan, E, Testini, M, Velmahos, G, Wani, I, Weber, D, Biffl, W, Coccolini, F, Catena, F, Tarasconi A., Perrone G., Davies J., Coimbra R., Moore E., Azzaroli F., Abongwa H., De Simone B., Gallo G., Rossi G., Abu-Zidan F., Agnoletti V., de'Angelis G., de'Angelis N., Ansaloni L., Baiocchi G. L., Carcoforo P., Ceresoli M., Chichom-Mefire A., Di Saverio S., Gaiani F., Giuffrida M., Hecker A., Inaba K., Kelly M., Kirkpatrick A., Kluger Y., Leppaniemi A., Litvin A., Ordonez C., Pattonieri V., Peitzman A., Pikoulis M., Sakakushev B., Sartelli M., Shelat V., Tan E., Testini M., Velmahos G., Wani I., Weber D., Biffl W., Coccolini F., and Catena F.
Abstract: Anorectal emergencies comprise a wide variety of diseases that share common symptoms, i.e., anorectal pain or bleeding and might require immediate management. While most of the underlying conditions do not need inpatient management, some of them could be life-threatening and need prompt recognition and treatment. It is well known that an incorrect diagnosis is frequent for anorectal diseases and that a delayed diagnosis is related to an impaired outcome. This paper aims to improve the knowledge and the awareness on this specific topic and to provide a useful tool for every physician dealing with anorectal emergencies. The present guidelines have been developed according to the GRADE methodology. To create these guidelines, a panel of experts was designed and charged by the boards of the World Society of Emergency Surgery (WSES) and American Association for the Surgery of Trauma (AAST) to perform a systematic review of the available literature and to provide evidence-based statements with immediate practical application. All the statements were presented and discussed during the WSES-AAST-WJES Consensus Conference on Anorectal Emergencies, and for each statement, a consensus among the WSES-AAST panel of experts was reached. We structured our work into seven main topics to cover the entire management of patients with anorectal emergencies and to provide an up-to-date, easy-to-use tool that can help physicians and surgeons during the decision-making process.
Published: 2021

18. 2020 WSES guidelines for the detection and management of bile duct injury during cholecystectomy

Author: De'Angelis, N, Catena, F, Memeo, R, Coccolini, F, Martinez-Perez, A, Romeo, O, De Simone, B, Di Saverio, S, Brustia, R, Rhaiem, R, Piardi, T, Conticchio, M, Marchegiani, F, Beghdadi, N, Abu-Zidan, F, Alikhanov, R, Allard, M, Allievi, N, Amaddeo, G, Ansaloni, L, Andersson, R, Andolfi, E, Azfar, M, Bala, M, Benkabbou, A, Ben-Ishay, O, Bianchi, G, Biffl, W, Brunetti, F, Carra, M, Casanova, D, Celentano, V, Ceresoli, M, Chiara, O, Cimbanassi, S, Bini, R, Coimbra, R, Luigi de'Angelis, G, Decembrino, F, De Palma, A, de Reuver, P, Domingo, C, Cotsoglou, C, Ferrero, A, Fraga, G, Gaiani, F, Gheza, F, Gurrado, A, Harrison, E, Henriquez, A, Hofmeyr, S, Iadarola, R, Kashuk, J, Kianmanesh, R, Kirkpatrick, A, Kluger, Y, Landi, F, Langella, S, Lapointe, R, Le Roy, B, Luciani, A, Machado, F, Maggi, U, Maier, R, Mefire, A, Hiramatsu, K, Ordonez, C, Patrizi, F, Planells, M, Peitzman, A, Pekolj, J, Perdigao, F, Pereira, B, Pessaux, P, Pisano, M, Puyana, J, Rizoli, S, Portigliotti, L, Romito, R, Sakakushev, B, Sanei, B, Scatton, O, Serradilla-Martin, M, Schneck, A, Sissoko, M, Sobhani, I, ten Broek, R, Testini, M, Valinas, R, Veloudis, G, Vitali, G, Weber, D, Zorcolo, L, Giuliante, F, Gavriilidis, P, Fuks, D, Sommacale, D, de'Angelis N., Catena F., Memeo R., Coccolini F., Martinez-Perez A., Romeo O. M., De Simone B., Di Saverio S., Brustia R., Rhaiem R., Piardi T., Conticchio M., Marchegiani F., Beghdadi N., Abu-Zidan F. M., Alikhanov R., Allard M. -A., Allievi N., Amaddeo G., Ansaloni L., Andersson R., Andolfi E., Azfar M., Bala M., Benkabbou A., Ben-Ishay O., Bianchi G., Biffl W. L., Brunetti F., Carra M. C., Casanova D., Celentano V., Ceresoli M., Chiara O., Cimbanassi S., Bini R., Coimbra R., Luigi de'Angelis G., Decembrino F., De Palma A., de Reuver P. R., Domingo C., Cotsoglou C., Ferrero A., Fraga G. P., Gaiani F., Gheza F., Gurrado A., Harrison E., Henriquez A., Hofmeyr S., Iadarola R., Kashuk J. L., Kianmanesh R., Kirkpatrick A. W., Kluger Y., Landi F., Langella S., Lapointe R., Le Roy B., Luciani A., Machado F., Maggi U., Maier R. V., Mefire A. C., Hiramatsu K., Ordonez C., Patrizi F., Planells M., Peitzman A. B., Pekolj J., Perdigao F., Pereira B. M., Pessaux P., Pisano M., Puyana J. C., Rizoli S., Portigliotti L., Romito R., Sakakushev B., Sanei B., Scatton O., Serradilla-Martin M., Schneck A. -S., Sissoko M. L., Sobhani I., ten Broek R. P., Testini M., Valinas R., Veloudis G., Vitali G. C., Weber D., Zorcolo L., Giuliante F., Gavriilidis P., Fuks D., Sommacale D., De'Angelis, N, Catena, F, Memeo, R, Coccolini, F, Martinez-Perez, A, Romeo, O, De Simone, B, Di Saverio, S, Brustia, R, Rhaiem, R, Piardi, T, Conticchio, M, Marchegiani, F, Beghdadi, N, Abu-Zidan, F, Alikhanov, R, Allard, M, Allievi, N, Amaddeo, G, Ansaloni, L, Andersson, R, Andolfi, E, Azfar, M, Bala, M, Benkabbou, A, Ben-Ishay, O, Bianchi, G, Biffl, W, Brunetti, F, Carra, M, Casanova, D, Celentano, V, Ceresoli, M, Chiara, O, Cimbanassi, S, Bini, R, Coimbra, R, Luigi de'Angelis, G, Decembrino, F, De Palma, A, de Reuver, P, Domingo, C, Cotsoglou, C, Ferrero, A, Fraga, G, Gaiani, F, Gheza, F, Gurrado, A, Harrison, E, Henriquez, A, Hofmeyr, S, Iadarola, R, Kashuk, J, Kianmanesh, R, Kirkpatrick, A, Kluger, Y, Landi, F, Langella, S, Lapointe, R, Le Roy, B, Luciani, A, Machado, F, Maggi, U, Maier, R, Mefire, A, Hiramatsu, K, Ordonez, C, Patrizi, F, Planells, M, Peitzman, A, Pekolj, J, Perdigao, F, Pereira, B, Pessaux, P, Pisano, M, Puyana, J, Rizoli, S, Portigliotti, L, Romito, R, Sakakushev, B, Sanei, B, Scatton, O, Serradilla-Martin, M, Schneck, A, Sissoko, M, Sobhani, I, ten Broek, R, Testini, M, Valinas, R, Veloudis, G, Vitali, G, Weber, D, Zorcolo, L, Giuliante, F, Gavriilidis, P, Fuks, D, Sommacale, D, de'Angelis N., Catena F., Memeo R., Coccolini F., Martinez-Perez A., Romeo O. M., De Simone B., Di Saverio S., Brustia R., Rhaiem R., Piardi T., Conticchio M., Marchegiani F., Beghdadi N., Abu-Zidan F. M., Alikhanov R., Allard M. -A., Allievi N., Amaddeo G., Ansaloni L., Andersson R., Andolfi E., Azfar M., Bala M., Benkabbou A., Ben-Ishay O., Bianchi G., Biffl W. L., Brunetti F., Carra M. C., Casanova D., Celentano V., Ceresoli M., Chiara O., Cimbanassi S., Bini R., Coimbra R., Luigi de'Angelis G., Decembrino F., De Palma A., de Reuver P. R., Domingo C., Cotsoglou C., Ferrero A., Fraga G. P., Gaiani F., Gheza F., Gurrado A., Harrison E., Henriquez A., Hofmeyr S., Iadarola R., Kashuk J. L., Kianmanesh R., Kirkpatrick A. W., Kluger Y., Landi F., Langella S., Lapointe R., Le Roy B., Luciani A., Machado F., Maggi U., Maier R. V., Mefire A. C., Hiramatsu K., Ordonez C., Patrizi F., Planells M., Peitzman A. B., Pekolj J., Perdigao F., Pereira B. M., Pessaux P., Pisano M., Puyana J. C., Rizoli S., Portigliotti L., Romito R., Sakakushev B., Sanei B., Scatton O., Serradilla-Martin M., Schneck A. -S., Sissoko M. L., Sobhani I., ten Broek R. P., Testini M., Valinas R., Veloudis G., Vitali G. C., Weber D., Zorcolo L., Giuliante F., Gavriilidis P., Fuks D., and Sommacale D.
Abstract: Bile duct injury (BDI) is a dangerous complication of cholecystectomy, with significant postoperative sequelae for the patient in terms of morbidity, mortality, and long-term quality of life. BDIs have an estimated incidence of 0.4–1.5%, but considering the number of cholecystectomies performed worldwide, mostly by laparoscopy, surgeons must be prepared to manage this surgical challenge. Most BDIs are recognized either during the procedure or in the immediate postoperative period. However, some BDIs may be discovered later during the postoperative period, and this may translate to delayed or inappropriate treatments. Providing a specific diagnosis and a precise description of the BDI will expedite the decision-making process and increase the chance of treatment success. Subsequently, the choice and timing of the appropriate reconstructive strategy have a critical role in long-term prognosis. Currently, a wide spectrum of multidisciplinary interventions with different degrees of invasiveness is indicated for BDI management. These World Society of Emergency Surgery (WSES) guidelines have been produced following an exhaustive review of the current literature and an international expert panel discussion with the aim of providing evidence-based recommendations to facilitate and standardize the detection and management of BDIs during cholecystectomy. In particular, the 2020 WSES guidelines cover the following key aspects: (1) strategies to minimize the risk of BDI during cholecystectomy; (2) BDI rates in general surgery units and review of surgical practice; (3) how to classify, stage, and report BDI once detected; (4) how to manage an intraoperatively detected BDI; (5) indications for antibiotic treatment; (6) indications for clinical, biochemical, and imaging investigations for suspected BDI; and (7) how to manage a postoperatively detected BDI.
Published: 2021

19. A pandemic recap: lessons we have learned

Author: Coccolini, F, Cicuttin, E, Cremonini, C, Tartaglia, D, Viaggi, B, Kuriyama, A, Picetti, E, Ball, C, Abu-Zidan, F, Ceresoli, M, Turri, B, Jain, S, Palombo, C, Guirao, X, Rodrigues, G, Gachabayov, M, Machado, F, Eftychios, L, Kanj, S, Di Carlo, I, Di Saverio, S, Khokha, V, Kirkpatrick, A, Massalou, D, Forfori, F, Corradi, F, Delibegovic, S, Machain Vega, G, Fantoni, M, Demetriades, D, Kapoor, G, Kluger, Y, Ansari, S, Maier, R, Leppaniemi, A, Hardcastle, T, Vereczkei, A, Karamagioli, E, Pikoulis, E, Pistello, M, Sakakushev, B, Navsaria, P, Galeiras, R, Yahya, A, Osipov, A, Dimitrov, E, Doklestic, K, Pisano, M, Malacarne, P, Carcoforo, P, Sibilla, M, Kryvoruchko, I, Bonavina, L, Kim, J, Shelat, V, Czepiel, J, Maseda, E, Marwah, S, Chirica, M, Biancofiore, G, Podda, M, Cobianchi, L, Ansaloni, L, Fugazzola, P, Seretis, C, Gomez, C, Tumietto, F, Malbrain, M, Reichert, M, Augustin, G, Amato, B, Puzziello, A, Hecker, A, Gemignani, A, Isik, A, Cucchetti, A, Nacoti, M, Kopelman, D, Mesina, C, Ghannam, W, Ben-Ishay, O, Dhingra, S, Coimbra, R, Moore, E, Cui, Y, Quiodettis, M, Bala, M, Testini, M, Diaz, J, Girardis, M, Biffl, W, Hecker, M, Sall, I, Boggi, U, Materazzi, G, Ghiadoni, L, Matsumoto, J, Zuidema, W, Ivatury, R, Enani, M, Litvin, A, Al-Hasan, M, Demetrashvili, Z, Baraket, O, Ordonez, C, Negoi, I, Kiguba, R, Memish, Z, Elmangory, M, Tolonen, M, Das, K, Ribeiro, J, O'Connor, D, Tan, B, Van Goor, H, Baral, S, De Simone, B, Corbella, D, Brambillasca, P, Scaglione, M, Basolo, F, De'Angelis, N, Bendinelli, C, Weber, D, Pagani, L, Monti, C, Baiocchi, G, Chiarugi, M, Catena, F, Sartelli, M, Coccolini F., Cicuttin E., Cremonini C., Tartaglia D., Viaggi B., Kuriyama A., Picetti E., Ball C., Abu-Zidan F., Ceresoli M., Turri B., Jain S., Palombo C., Guirao X., Rodrigues G., Gachabayov M., Machado F., Eftychios L., Kanj S. S., Di Carlo I., Di Saverio S., Khokha V., Kirkpatrick A., Massalou D., Forfori F., Corradi F., Delibegovic S., Machain Vega G. M., Fantoni M., Demetriades D., Kapoor G., Kluger Y., Ansari S., Maier R., Leppaniemi A., Hardcastle T., Vereczkei A., Karamagioli E., Pikoulis E., Pistello M., Sakakushev B. E., Navsaria P. H., Galeiras R., Yahya A. I., Osipov A. V., Dimitrov E., Doklestic K., Pisano M., Malacarne P., Carcoforo P., Sibilla M. G., Kryvoruchko I. A., Bonavina L., Kim J. I., Shelat V. G., Czepiel J., Maseda E., Marwah S., Chirica M., Biancofiore G., Podda M., Cobianchi L., Ansaloni L., Fugazzola P., Seretis C., Gomez C. A., Tumietto F., Malbrain M., Reichert M., Augustin G., Amato B., Puzziello A., Hecker A., Gemignani A., Isik A., Cucchetti A., Nacoti M., Kopelman D., Mesina C., Ghannam W., Ben-Ishay O., Dhingra S., Coimbra R., Moore E. E., Cui Y., Quiodettis M. A., Bala M., Testini M., Diaz J., Girardis M., Biffl W. L., Hecker M., Sall I., Boggi U., Materazzi G., Ghiadoni L., Matsumoto J., Zuidema W. P., Ivatury R., Enani M. A., Litvin A., Al-Hasan M. N., Demetrashvili Z., Baraket O., Ordonez C. A., Negoi I., Kiguba R., Memish Z. A., Elmangory M. M., Tolonen M., Das K., Ribeiro J., O'Connor D. B., Tan B. K., Van Goor H., Baral S., De Simone B., Corbella D., Brambillasca P., Scaglione M., Basolo F., De'Angelis N., Bendinelli C., Weber D., Pagani L., Monti C., Baiocchi G., Chiarugi M., Catena F., Sartelli M., Coccolini, F, Cicuttin, E, Cremonini, C, Tartaglia, D, Viaggi, B, Kuriyama, A, Picetti, E, Ball, C, Abu-Zidan, F, Ceresoli, M, Turri, B, Jain, S, Palombo, C, Guirao, X, Rodrigues, G, Gachabayov, M, Machado, F, Eftychios, L, Kanj, S, Di Carlo, I, Di Saverio, S, Khokha, V, Kirkpatrick, A, Massalou, D, Forfori, F, Corradi, F, Delibegovic, S, Machain Vega, G, Fantoni, M, Demetriades, D, Kapoor, G, Kluger, Y, Ansari, S, Maier, R, Leppaniemi, A, Hardcastle, T, Vereczkei, A, Karamagioli, E, Pikoulis, E, Pistello, M, Sakakushev, B, Navsaria, P, Galeiras, R, Yahya, A, Osipov, A, Dimitrov, E, Doklestic, K, Pisano, M, Malacarne, P, Carcoforo, P, Sibilla, M, Kryvoruchko, I, Bonavina, L, Kim, J, Shelat, V, Czepiel, J, Maseda, E, Marwah, S, Chirica, M, Biancofiore, G, Podda, M, Cobianchi, L, Ansaloni, L, Fugazzola, P, Seretis, C, Gomez, C, Tumietto, F, Malbrain, M, Reichert, M, Augustin, G, Amato, B, Puzziello, A, Hecker, A, Gemignani, A, Isik, A, Cucchetti, A, Nacoti, M, Kopelman, D, Mesina, C, Ghannam, W, Ben-Ishay, O, Dhingra, S, Coimbra, R, Moore, E, Cui, Y, Quiodettis, M, Bala, M, Testini, M, Diaz, J, Girardis, M, Biffl, W, Hecker, M, Sall, I, Boggi, U, Materazzi, G, Ghiadoni, L, Matsumoto, J, Zuidema, W, Ivatury, R, Enani, M, Litvin, A, Al-Hasan, M, Demetrashvili, Z, Baraket, O, Ordonez, C, Negoi, I, Kiguba, R, Memish, Z, Elmangory, M, Tolonen, M, Das, K, Ribeiro, J, O'Connor, D, Tan, B, Van Goor, H, Baral, S, De Simone, B, Corbella, D, Brambillasca, P, Scaglione, M, Basolo, F, De'Angelis, N, Bendinelli, C, Weber, D, Pagani, L, Monti, C, Baiocchi, G, Chiarugi, M, Catena, F, Sartelli, M, Coccolini F., Cicuttin E., Cremonini C., Tartaglia D., Viaggi B., Kuriyama A., Picetti E., Ball C., Abu-Zidan F., Ceresoli M., Turri B., Jain S., Palombo C., Guirao X., Rodrigues G., Gachabayov M., Machado F., Eftychios L., Kanj S. S., Di Carlo I., Di Saverio S., Khokha V., Kirkpatrick A., Massalou D., Forfori F., Corradi F., Delibegovic S., Machain Vega G. M., Fantoni M., Demetriades D., Kapoor G., Kluger Y., Ansari S., Maier R., Leppaniemi A., Hardcastle T., Vereczkei A., Karamagioli E., Pikoulis E., Pistello M., Sakakushev B. E., Navsaria P. H., Galeiras R., Yahya A. I., Osipov A. V., Dimitrov E., Doklestic K., Pisano M., Malacarne P., Carcoforo P., Sibilla M. G., Kryvoruchko I. A., Bonavina L., Kim J. I., Shelat V. G., Czepiel J., Maseda E., Marwah S., Chirica M., Biancofiore G., Podda M., Cobianchi L., Ansaloni L., Fugazzola P., Seretis C., Gomez C. A., Tumietto F., Malbrain M., Reichert M., Augustin G., Amato B., Puzziello A., Hecker A., Gemignani A., Isik A., Cucchetti A., Nacoti M., Kopelman D., Mesina C., Ghannam W., Ben-Ishay O., Dhingra S., Coimbra R., Moore E. E., Cui Y., Quiodettis M. A., Bala M., Testini M., Diaz J., Girardis M., Biffl W. L., Hecker M., Sall I., Boggi U., Materazzi G., Ghiadoni L., Matsumoto J., Zuidema W. P., Ivatury R., Enani M. A., Litvin A., Al-Hasan M. N., Demetrashvili Z., Baraket O., Ordonez C. A., Negoi I., Kiguba R., Memish Z. A., Elmangory M. M., Tolonen M., Das K., Ribeiro J., O'Connor D. B., Tan B. K., Van Goor H., Baral S., De Simone B., Corbella D., Brambillasca P., Scaglione M., Basolo F., De'Angelis N., Bendinelli C., Weber D., Pagani L., Monti C., Baiocchi G., Chiarugi M., Catena F., and Sartelli M.
Abstract: On January 2020, the WHO Director General declared that the outbreak constitutes a Public Health Emergency of International Concern. The world has faced a worldwide spread crisis and is still dealing with it. The present paper represents a white paper concerning the tough lessons we have learned from the COVID-19 pandemic. Thus, an international and heterogenous multidisciplinary panel of very differentiated people would like to share global experiences and lessons with all interested and especially those responsible for future healthcare decision making. With the present paper, international and heterogenous multidisciplinary panel of very differentiated people would like to share global experiences and lessons with all interested and especially those responsible for future healthcare decision making.
Published: 2021

20. Diagnostic, therapeutic and health-care management protocol in thyroid surgery: a position statement of the Italian Association of Endocrine Surgery Units (U.E.C. CLUB)

Author: Rosato, L., De Crea, C., Bellantone, R., Brandi, M. L., De Toma, G., Filetti, S., Miccoli, P., Pacini, F., Pelizzo, M. R., Pontecorvi, A., Avenia, N., De Pasquale, L., Chiofalo, M. G., Gurrado, A., Innaro, N., La Valle, G., Lombardi, C. P., Marini, P. L., Mondini, G., Mullineris, B., Pezzullo, L., Raffaelli, M., Testini, M., and De Palma, M.
Published: 2016
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21. Impact of the COVID-19 pandemic on surgery for thyroid cancer in Italy: nationwide retrospective study

Author: Medas, F., Ansaldo, G. L., Avenia, N., Basili, G., Bononi, M., Bove, A., Carcoforo, P., Casaril, A., Cavallaro, G., Conzo, G., De Pasquale, L., Del Rio, P., Dionigi, G., Dobrinja, C., Docimo, G., Graceffa, G., Iacobone, M., Innaro, N., Lombardi, C. P., Novelli, G., Palestini, N., Pedicini, F., Perigli, G., Pezzolla, A., Pezzullo, L., Scerrino, G., Spiezia, S., Testini, M., Calo, P. G., Anedda, G., Antonelli, G., Arrigoni, G., Badii, B., Bonati, E., Boniardi, M., Bulfamante, A. M., Candalise, V., Cangiano, A., Canu, G. L., Cappellacci, F., Caracciolo, A., Caruso, E., Casal Ide, E., Chiappini, A., Chiofalo, M. G., Cipolla, C., Costigliola, L., Cozzani, F., Crocco, A., Crocetti, D., De Manzini, N., DI Gioia, A., DI Resta, V., Eramo, R., Erdas, E., Ferriolo, S., Filardo, M., Filograna Pignatelli, M., Gervasi, R., Giudici, F., Gordini, L., Gurrado, A., Impellizzeri, H., Inama, M., Koleva Radica, M., Laforgia, R., Lattarulo, S., Loderer, T., Lucchini, R., Mascioli, F., Marcellinaro, R., Menditto, R., Melfa, G., Minuto, M., Misso, C., Offi, C., Orlando, G., Ossola, P., Pagetta, C., Pasculli, A., Patrone, R., Pauna, I., Pennetti Pennella, F., Pietrasanta, D., Pino, A., Pinto, V. L., Piras, S., Polistena, A., Portinari, M., Reina, S., Rotolo, G., Russo, G., Scalise, E., Sgaramella, L. I., Sibilla, M. G., Spinelli, S., Spoletini, D., Curto, L. S., Tascone, M., Torresan, F., Varaldo, E., Viviani, E., Zucca, A., Medas, F, Ansaldo, G L, Avenia, N, Basili, G, Bononi, M, Bove, A, Carcoforo, P, Casaril, A, Cavallaro, G, Conzo, G, De Pasquale, L, Del Rio, P, Dionigi, G, Dobrinja, C, Docimo, G, Graceffa, G, Iacobone, M, Innaro, N, Lombardi, C P, Novelli, G, Palestini, N, Pedicini, F, Perigli, G, Pezzolla, A, Pezzullo, L, Scerrino, G, Spiezia, S, Testini, M, Calò, P G, Cipolla C, Medas, F., Ansaldo, G. L., Avenia, N., Basili, G., Bononi, M., Bove, A., Carcoforo, P., Casaril, A., Cavallaro, G., Conzo, G., De Pasquale, L., Del Rio, P., Dionigi, G., Dobrinja, C., Docimo, G., Graceffa, G., Iacobone, M., Innaro, N., Lombardi, C. P., Novelli, G., Palestini, N., Pedicini, F., Perigli, G., Pezzolla, A., Pezzullo, L., Scerrino, G., Spiezia, S., Testini, M., Calo, P. G., Anedda, G., Antonelli, G., Arrigoni, G., Badii, B., Bonati, E., Boniardi, M., Bulfamante, A. M., Candalise, V., Cangiano, A., Canu, G. L., Cappellacci, F., Caracciolo, A., Caruso, E., Casal Ide, E., Chiappini, A., Chiofalo, M. G., Cipolla, C., Costigliola, L., Cozzani, F., Crocco, A., Crocetti, D., De Manzini, N., DI Gioia, A., DI Resta, V., Eramo, R., Erdas, E., Ferriolo, S., Filardo, M., Filograna Pignatelli, M., Gervasi, R., Giudici, F., Gordini, L., Gurrado, A., Impellizzeri, H., Inama, M., Koleva Radica, M., Laforgia, R., Lattarulo, S., Loderer, T., Lucchini, R., Mascioli, F., Marcellinaro, R., Menditto, R., Melfa, G., Minuto, M., Misso, C., Offi, C., Orlando, G., Ossola, P., Pagetta, C., Pasculli, A., Patrone, R., Pauna, I., Pennetti Pennella, F., Pietrasanta, D., Pino, A., Pinto, V. L., Piras, S., Polistena, A., Portinari, M., Reina, S., Rotolo, G., Russo, G., Scalise, E., Sgaramella, L. I., Sibilla, M. G., Spinelli, S., Spoletini, D., Curto, L. S., Tascone, M., Torresan, F., Varaldo, E., Viviani, E., and Zucca, A.
Subjects: 2019-20 coronavirus outbreak, medicine.medical_specialty, AcademicSubjects/MED00910, Coronavirus disease 2019 (COVID-19), medicine.medical_treatment, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), pandemics, NO, Pandemic, Research Letter, medicine, humans, Thyroid cancer, Thyroid Neoplasm, LS7_4, Thyroid Neoplasms, Thyroidectomy, SARS-CoV-2, COVID-19, Pandemics, Italy, business.industry, thyroid neoplasms, Retrospective cohort study, medicine.disease, Comorbidity, comorbidity, retrospective studies, thyroidectomy, Settore MED/18 - Chirurgia Generale, Emergency medicine, Surgery, AcademicSubjects/MED00010, business
Abstract: N/A
Published: 2021

22. Achieving the learning curve in total thyroidectomy: a prospective evaluation on resident’s training by CUSUM and KPSS analysis

Author: Tarallo, M, primary, Crocetti, D, additional, Gurrado, A, additional, Iorio, O, additional, Iossa, A, additional, Caruso, D, additional, Bononi, M, additional, Stabilini, C, additional, Bracale, U, additional, Chiappini, A, additional, Testini, M, additional, Avenia, N, additional, Polistena, A, additional, and Cavallaro, G, additional
Published: 2022
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23. The SIFIPAC/WSES/SICG/SIMEU guidelines for diagnosis and treatment of acute appendicitis in the elderly (2019 edition)

Author: Fugazzola, P, Ceresoli, M, Agnoletti, V, Agresta, F, Amato, B, Carcoforo, P, Catena, F, Chiara, O, Chiarugi, M, Cobianchi, L, Coccolini, F, De Troia, A, Di Saverio, S, Fabbri, A, Feo, C, Gabrielli, F, Gurrado, A, Guttadauro, A, Leone, L, Marrelli, D, Petruzzelli, L, Portolani, N, Prete, F, Puzziello, A, Sartelli, M, Soliani, G, Testini, M, Tolone, S, Tomasoni, M, Tugnoli, G, Viale, P, Zese, M, Ishay, O, Kluger, Y, Kirkpatrick, A, Ansaloni, L, Fugazzola P., Ceresoli M., Agnoletti V., Agresta F., Amato B., Carcoforo P., Catena F., Chiara O., Chiarugi M., Cobianchi L., Coccolini F., De Troia A., Di Saverio S., Fabbri A., Feo C., Gabrielli F., Gurrado A., Guttadauro A., Leone L., Marrelli D., Petruzzelli L., Portolani N., Prete F. P., Puzziello A., Sartelli M., Soliani G., Testini M., Tolone S., Tomasoni M., Tugnoli G., Viale P., Zese M., Ishay O. B., Kluger Y., Kirkpatrick A., Ansaloni L., Fugazzola, P, Ceresoli, M, Agnoletti, V, Agresta, F, Amato, B, Carcoforo, P, Catena, F, Chiara, O, Chiarugi, M, Cobianchi, L, Coccolini, F, De Troia, A, Di Saverio, S, Fabbri, A, Feo, C, Gabrielli, F, Gurrado, A, Guttadauro, A, Leone, L, Marrelli, D, Petruzzelli, L, Portolani, N, Prete, F, Puzziello, A, Sartelli, M, Soliani, G, Testini, M, Tolone, S, Tomasoni, M, Tugnoli, G, Viale, P, Zese, M, Ishay, O, Kluger, Y, Kirkpatrick, A, Ansaloni, L, Fugazzola P., Ceresoli M., Agnoletti V., Agresta F., Amato B., Carcoforo P., Catena F., Chiara O., Chiarugi M., Cobianchi L., Coccolini F., De Troia A., Di Saverio S., Fabbri A., Feo C., Gabrielli F., Gurrado A., Guttadauro A., Leone L., Marrelli D., Petruzzelli L., Portolani N., Prete F. P., Puzziello A., Sartelli M., Soliani G., Testini M., Tolone S., Tomasoni M., Tugnoli G., Viale P., Zese M., Ishay O. B., Kluger Y., Kirkpatrick A., and Ansaloni L.
Abstract: The epidemiology and the outcomes of acute appendicitis in elderly patients are very different from the younger population. Elderly patients with acute appendicitis showed higher mortality, higher perforation rate, lower diagnostic accuracy, longer delay from symptoms onset and admission, higher postoperative complication rate and higher risk of colonic and appendiceal cancer. The aim of the present work was to investigate age-related factors that could influence a different approach, compared to the 2016 WSES Jerusalem guidelines on general population, in terms of diagnosis and management of elderly patient with acute appendicitis. During the XXIX National Congress of the Italian Society of Surgical Pathophysiology (SIFIPAC) held in Cesena (Italy) in May 2019, in collaboration with the Italian Society of Geriatric Surgery (SICG), the World Society of Emergency Surgery (WSES) and the Italian Society of Emergency Medicine (SIMEU), a panel of experts participated to a Consensus Conference where eight panelists presented a number of statements, which were developed for each of the four topics about diagnosis and management of acute appendicitis in elderly patients, formulated according to the GRADE system. The statements were then voted, eventually modified and finally approved by the participants to the Consensus Conference. The current paper is reporting the definitive guidelines statements on each of the following topics: diagnosis, non-operative management, operative management and antibiotic therapy.
Published: 2020

24. The critical view of safety during laparoscopic cholecystectomy: Strasberg Yes or No? An Italian Multicentre study

Author: Sgaramella, L. I., Gurrado, A., Pasculli, A., de Angelis, N., Memeo, R., Prete, F. P., Berti, S., Ceccarelli, G., Rigamonti, M., Badessi, F. G. A., Solari, N., Milone, M., Catena, F., Scabini, S., Vittore, F., Perrone, G., de Werra, C., Cafiero, F., Testini, M., Baiocchi, G. L., Baldazzi, G., Battocletti, M., Bertoglio, S., Bianco, P., Bugiantella, W., Ciaccio, G., Cobianchi, L., Conzo, G., Crespi, M., De Rosa, M., Di Meo, G., Docimo, L., Fabris, L., Feleppa, C., Ferraro, V., Fontana, T., Gambardella, C., Gennai, A., Guida, F., Invernizzi, L., Massobrio, A., Medas, F., Monaco, L., Muntoni, G., Musella, M., Palombo, D., Perinotti, R., Pertile, D., Pezzolla, A., Piccirillo, G., Polastri, R., Ruggiero, R., Scatizzi, M., Somaglino, C., Tolone, S., Traverso, E., Tutino, R., Valduga, C., Zuolo, M., Sgaramella, L. I., Gurrado, A., Pasculli, A., de Angelis, N., Memeo, R., Prete, F. P., Berti, S., Ceccarelli, G., Rigamonti, M., Badessi, F. G. A., Solari, N., Milone, M., Catena, F., Scabini, S., Vittore, F., Perrone, G., de Werra, C., Cafiero, F., Testini, M., Baiocchi, G. L., Baldazzi, G., Battocletti, M., Bertoglio, S., Bianco, P., Bugiantella, W., Ciaccio, G., Cobianchi, L., Conzo, G., Crespi, M., De Rosa, M., Di Meo, G., Docimo, L., Fabris, L., Feleppa, C., Ferraro, V., Fontana, T., Gambardella, C., Gennai, A., Guida, F., Invernizzi, L., Massobrio, A., Medas, F., Monaco, L., Muntoni, G., Musella, M., Palombo, D., Perinotti, R., Pertile, D., Pezzolla, A., Piccirillo, G., Polastri, R., Ruggiero, R., Scatizzi, M., Somaglino, C., Tolone, S., Traverso, E., Tutino, R., Valduga, C., Zuolo, M., Sgaramella L.I., Gurrado A., Pasculli A., de Angelis N., Memeo R., Prete F.P., Berti S., Ceccarelli G., Rigamonti M., Badessi F.G.A., Solari N., Milone M., Catena F., Scabini S., Vittore F., Perrone G., de Werra C., Cafiero F., Testini M., Baiocchi G.L., Baldazzi G., Battocletti M., Bertoglio S., Bianco P., Bugiantella W., Ciaccio G., Cobianchi L., Conzo G., Crespi M., De Rosa M., Di Meo G., Docimo L., Fabris L., Feleppa C., Ferraro V., Fontana T., Gambardella C., Gennai A., Guida F., Invernizzi L., Massobrio A., Medas F., Monaco L., Muntoni G., Musella M., Palombo D., Perinotti R., Pertile D., Pezzolla A., Piccirillo G., Polastri R., Ruggiero R., Scatizzi M., Somaglino C., Tolone S., Traverso E., Tutino R., Valduga C., and Zuolo M.
Subjects: medicine.medical_specialty, Critical view of safety, medicine.medical_treatment, Laparoscopic training, bBile duct injuries, Bile duct injuries, Cholecystectomy, Intraoperative bleeding, Laparoscopy, Bile Duct Diseases, Article, cholecystectomy, critical view of safety, intraoperative bleeding, laparoscopic training, laparoscopy, Medicine, Humans, Intraoperative Complications, medicine.diagnostic_test, business.industry, Bile duct, General surgery, Gallbladder, Incidence (epidemiology), Gold standard, Perioperative, medicine.anatomical_structure, Cholecystectomy, Laparoscopic, Italy, Surgery, Bile Ducts, business, Bile duct injurie, Abdominal surgery
Abstract: Background Laparoscopic cholecystectomy is considered the gold standard for the treatment of gallbladder lithiasis; nevertheless, the incidence of bile duct injuries (BDI) is still high (0.3–0.8%) compared to open cholecystectomy (0.2%). In 1995, Strasberg introduced the "Critical View of Safety" (CVS) to reduce the risk of BDI. Despite its widespread use, the scientific evidence supporting this technique to prevent BDI is controversial. Methods Between March 2017 and March 2019, the data of patients submitted to laparoscopic cholecystectomy in 30 Italian surgical departments were collected on a national database. A survey was submitted to all members of Italian Digestive Pathology Society to obtain data on the preoperative workup, the surgical and postoperative management of patients and to judge, at the end of the procedure, if the isolation of the elements was performed according to the CVS. In the case of a declared critical view, iconographic documentation was obtained, finally reviewed by an external auditor. Results Data from 604 patients were analysed. The study population was divided into two groups according to the evidence (Group A; n = 11) or absence (Group B; N = 593) of BDI and perioperative bleeding. The non-use of CVS was found in 54.6% of procedures in the Group A, and 25.8% in the Group B, and evaluating the operator-related variables the execution of CVS was associated with a significantly lower incidence of BDI and intraoperative bleeding. Conclusions The CVS confirmed to be the safest technique to recognize the elements of the Calot triangle and, if correctly performed, it significantly impacted on preventing intraoperative complications. Additional educational programs on the correct application of CVS in clinical practice would be desirable to avoid extreme conditions that may require additional procedures.
Published: 2020

25. Impact of pericardium bovine patch (Tutomesh®) on incisional hernia treatment in contaminated or potentially contaminated fields: retrospective comparative study

Author: Gurrado, A., Franco, I. F., Lissidini, G., Greco, G., De Fazio, M., Pasculli, A., Girardi, A., Piccinni, G., Memeo, V., and Testini, M.
Published: 2015
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26. The THYCOVIT (Thyroid Surgery during COVID-19 pandemic in Italy) study: results from a nationwide, multicentric, case-controlled study

Author: Medas, F., Ansaldo, G. L., Avenia, N., Basili, G., Boniardi, M., Bononi, M., Bove, A., Carcoforo, P., Casaril, A., Cavallaro, G., Chiofalo, M. G., Conzo, G., De Pasquale, L., Del Rio, P., Dionigi, G., Dobrinja, C., Docimo, G., Graceffa, G., Iacobone, M., Innaro, N., Lombardi, C. P., Palestini, N., Pedicini, F., Perigli, G., Pezzolla, A., Scerrino, G., Spiezia, S., Testini, M., Calo, P. G., Anedda, G., Antonelli, G., Arrigoni, G., Badii, B., Bonati, E., Bulfamante, A. M., Candalise, V., Cangiano, A., Canu, G. L., Cappellacci, F., Caracciolo, A., Caruso, E., Annamaria, D. A., Ide, E. C., Chiappini, A., Cipolla, C., Costigliola, L., Cozzani, F., Crocco, A., Crocetti, D., Demanzini, N., Digioia, A., Diresta, V., Eramo, R., Erdas, E., Ferriolo, S., Filardo, M., Filograna Pignatelli, M., Gervasi, R., Giudici, F., Gordini, L., Gurrado, A., Impellizzeri, H., Inama, M., Koleva Radica, M., Laforgia, R., Lattarulo, S., Loderer, T., Lucchini, R., Mascioli, F., Marcellinaro, R., Menditto, R., Melfa, G., Minuto, M., Misso, C., Offi, C., Orlando, G., Ossola, P., Pagetta, C., Pasculli, A., Patrone, R., Pauna, I., Pennetti Pennella, F., Pietrasanta, D., Pino, A., Pinto, V. L., Piras, S., Polistena, A., Portinari, M., Reina, S., Rotolo, G., Russo, G., Scalise, E., Sgaramella, L. I., Sibilla, M. G., Spinelli, S., Spoletini, D., Curto, L. S., Tascone, M., Torresan, F., Varaldo, E., Viviani, E., Zucca, A., Medas, Fabio, Ansaldo, Gian Luca, Avenia, Nicola, Basili, Giancarlo, Boniardi, Marco, Bononi, Marco, Bove, Aldo, Carcoforo, Paolo, Casaril, Andrea, Cavallaro, Giuseppe, Chiofalo, Maria Grazia, Conzo, Giovanni, De Pasquale, Loredana, Del Rio, Paolo, Dionigi, Gianlorenzo, Dobrinja, Chiara, Docimo, Giovanni, Graceffa, Giuseppa, Iacobone, Maurizio, Innaro, Nadia, Lombardi, Celestino Pio, Palestini, Nicola, Pedicini, Francesco, Perigli, Giuliano, Pezzolla, Angela, Scerrino, Gregorio, Spiezia, Stefano, Testini, Mario, Calò, Pietro Giorgio, Calogero, Cipolla, Medas, F., Ansaldo, G. L., Avenia, N., Basili, G., Boniardi, M., Bononi, M., Bove, A., Carcoforo, P., Casaril, A., Cavallaro, G., Chiofalo, M. G., Conzo, G., De Pasquale, L., Del Rio, P., Dionigi, G., Dobrinja, C., Docimo, G., Graceffa, G., Iacobone, M., Innaro, N., Lombardi, C. P., Palestini, N., Pedicini, F., Perigli, G., Pezzolla, A., Scerrino, G., Spiezia, S., Testini, M., Calo, P. G., Anedda, G., Antonelli, G., Arrigoni, G., Badii, B., Bonati, E., Bulfamante, A. M., Candalise, V., Cangiano, A., Canu, G. L., Cappellacci, F., Caracciolo, A., Caruso, E., Annamaria, D. A., Ide, E. C., Chiappini, A., Cipolla, C., Costigliola, L., Cozzani, F., Crocco, A., Crocetti, D., Demanzini, N., Digioia, A., Diresta, V., Eramo, R., Erdas, E., Ferriolo, S., Filardo, M., Filograna Pignatelli, M., Gervasi, R., Giudici, F., Gordini, L., Gurrado, A., Impellizzeri, H., Inama, M., Koleva Radica, M., Laforgia, R., Lattarulo, S., Loderer, T., Lucchini, R., Mascioli, F., Marcellinaro, R., Menditto, R., Melfa, G., Minuto, M., Misso, C., Offi, C., Orlando, G., Ossola, P., Pagetta, C., Pasculli, A., Patrone, R., Pauna, I., Pennetti Pennella, F., Pietrasanta, D., Pino, A., Pinto, V. L., Piras, S., Polistena, A., Portinari, M., Reina, S., Rotolo, G., Russo, G., Scalise, E., Sgaramella, L. I., Sibilla, M. G., Spinelli, S., Spoletini, D., Curto, L. S., Tascone, M., Torresan, F., Varaldo, E., Viviani, E., and Zucca, A.
Subjects: COVID-19, Endocrine surgery, SARS-CoV-2, Thyroid carcinoma, Thyroidectomy, medicine.medical_specialty, medicine.medical_treatment, Thyroid Gland, Humans, Italy, Retrospective Studies, Pandemics, NO, Retrospective Studie, Pandemic, Epidemiology, medicine, Thyroid cancer, LS7_4, business.industry, Thyroid disease, Case-control study, Retrospective cohort study, medicine.disease, Surgery, Original Article, business, Human
Abstract: The outbreak of the COVID-19 pandemic has led to a disruption of surgical care. The aim of this multi-centric, retrospective study was to evaluate the impact of the pandemic on surgical activity for thyroid disease among the Italian Units of Endocrine Surgery. Three phases of the pandemic were identified based on the epidemiological situation and the public measures adopted from the Italian Government (1st phase: from 9th March to 3rd May 2020; 2nd phase: from 4th May to 14th June; 3rd phase: from 15th June to 31st). The patients operated upon during these phases were compared to those who underwent surgery during the same period of the previous year. Overall, 3892 patients from 28 Italian endocrine surgical units were included in the study, 1478 (38%) operated upon during COVID-19 pandemic, and 2414 (62%) during the corresponding period of 2019. The decrease in the number of operations was by 64.8%, 44.7% and 5.1% during the three phases of COVID-19 pandemic, compared to 2019, respectively. During the first and the second phases, the surgical activity was dedicated mainly to oncological patients. No differences in post-operative complications were noted between the two periods. Oncological activity for thyroid cancer was adequately maintained during the COVID-19 pandemic.
Published: 2021

27. Diagnostic, therapeutic and healthcare management protocols in parathyroid surgery: II Consensus Conference of the Italian Association of Endocrine Surgery Units (U.E.C. CLUB)

Author: Rosato, L., Raffaelli, M., Bellantone, R., Pontecorvi, A., Avenia, N., Boniardi, M., Brandi, M. L., Cetani, F., Chiofalo, M. G., Conzo, G., De Palma, M., Gasparri, G., Giordano, A., Innaro, N., Leopaldi, E., Mariani, G., Marcocci, C., Marini, P., Miccoli, P., Nasi, P., Pacini, F., Paragliola, R., Pelizzo, M. R., Testini, M., and De Toma, G.
Published: 2014
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28. Hemithyroidectomy versus total thyroidectomy in the intermediate-risk differentiated thyroid cancer: the Italian Societies of Endocrine Surgeons and Surgical Oncology Multicentric Study

Author: Dobrinja, C., primary, Samardzic, N., additional, Giudici, F., additional, Raffaelli, M., additional, De Crea, C., additional, Sessa, L., additional, Docimo, G., additional, Ansaldo, G. L., additional, Minuto, M., additional, Varaldo, E., additional, Dionigi, G., additional, Spiezia, S., additional, Boniardi, M., additional, Pauna, I., additional, De Pasquale, L., additional, Testini, M., additional, Gurrado, A., additional, Pasculli, A., additional, Pezzolla, A., additional, Lattarulo, S., additional, Calò, P. G., additional, Graceffa, G., additional, Massara, A., additional, Docimo, L., additional, Ruggiero, R., additional, Parmeggiani, D., additional, Iacobone, M., additional, Innaro, N., additional, Lombardi, C. P., additional, and de Manzini, N., additional
Published: 2021
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29. A pandemic recap: lessons we have learned

Author: Coccolini, F., Cicuttin, E., Cremonini, C., Tartaglia, D., Viaggi, B., Kuriyama, A., Picetti, E., Ball, C., Abu-Zidan, F., Ceresoli, M., Turri, B., Jain, S., Palombo, C., Guirao, X., Rodrigues, G., Gachabayov, M., Machado, F., Eftychios, L., Kanj, S.S., Carlo, I. Di, Saverio, S. Di, Khokha, V., Kirkpatrick, A., Massalou, D., Forfori, F., Corradi, F., Delibegovic, S., Vega, G.M. Machain, Fantoni, M., Demetriades, D., Kapoor, G., Kluger, Y., Ansari, S., Maier, R., Leppaniemi, A., Hardcastle, T., Vereczkei, A., Karamagioli, E., Pikoulis, E., Pistello, M., Sakakushev, B.E., Navsaria, P.H., Galeiras, R., Yahya, A.I., Osipov, A.V., Dimitrov, E., Doklestić, K., Pisano, M., Malacarne, P., Carcoforo, P., Sibilla, M.G., Kryvoruchko, I.A., Bonavina, L., Kim, J.I., Shelat, V.G., Czepiel, J., Maseda, E., Marwah, S., Chirica, M., Biancofiore, G., Podda, M., Cobianchi, L., Ansaloni, L., Fugazzola, P., Seretis, C., Gomez, C.A., Tumietto, F., Malbrain, M., Reichert, M., Augustin, G., Amato, B., Puzziello, A., Hecker, A., Gemignani, A., Isik, A., Cucchetti, A., Nacoti, M., Kopelman, D., Mesina, C., Ghannam, W., Ben-Ishay, O., Dhingra, S., Coimbra, R., Moore, E.E., Cui, Y., Quiodettis, M.A., Bala, M., Testini, M., Diaz, J., Girardis, M., Biffl, W.L., Hecker, M., Sall, I., Boggi, U., Materazzi, G., Ghiadoni, L., Matsumoto, J., Zuidema, W.P., Ivatury, R., Enani, M.A., Goor, H. van, Catena, Fausto, Sartelli, M., Coccolini, F., Cicuttin, E., Cremonini, C., Tartaglia, D., Viaggi, B., Kuriyama, A., Picetti, E., Ball, C., Abu-Zidan, F., Ceresoli, M., Turri, B., Jain, S., Palombo, C., Guirao, X., Rodrigues, G., Gachabayov, M., Machado, F., Eftychios, L., Kanj, S.S., Carlo, I. Di, Saverio, S. Di, Khokha, V., Kirkpatrick, A., Massalou, D., Forfori, F., Corradi, F., Delibegovic, S., Vega, G.M. Machain, Fantoni, M., Demetriades, D., Kapoor, G., Kluger, Y., Ansari, S., Maier, R., Leppaniemi, A., Hardcastle, T., Vereczkei, A., Karamagioli, E., Pikoulis, E., Pistello, M., Sakakushev, B.E., Navsaria, P.H., Galeiras, R., Yahya, A.I., Osipov, A.V., Dimitrov, E., Doklestić, K., Pisano, M., Malacarne, P., Carcoforo, P., Sibilla, M.G., Kryvoruchko, I.A., Bonavina, L., Kim, J.I., Shelat, V.G., Czepiel, J., Maseda, E., Marwah, S., Chirica, M., Biancofiore, G., Podda, M., Cobianchi, L., Ansaloni, L., Fugazzola, P., Seretis, C., Gomez, C.A., Tumietto, F., Malbrain, M., Reichert, M., Augustin, G., Amato, B., Puzziello, A., Hecker, A., Gemignani, A., Isik, A., Cucchetti, A., Nacoti, M., Kopelman, D., Mesina, C., Ghannam, W., Ben-Ishay, O., Dhingra, S., Coimbra, R., Moore, E.E., Cui, Y., Quiodettis, M.A., Bala, M., Testini, M., Diaz, J., Girardis, M., Biffl, W.L., Hecker, M., Sall, I., Boggi, U., Materazzi, G., Ghiadoni, L., Matsumoto, J., Zuidema, W.P., Ivatury, R., Enani, M.A., Goor, H. van, Catena, Fausto, and Sartelli, M.
Abstract: Contains fulltext : 238976.pdf (Publisher’s version ) (Open Access), On January 2020, the WHO Director General declared that the outbreak constitutes a Public Health Emergency of International Concern. The world has faced a worldwide spread crisis and is still dealing with it. The present paper represents a white paper concerning the tough lessons we have learned from the COVID-19 pandemic. Thus, an international and heterogenous multidisciplinary panel of very differentiated people would like to share global experiences and lessons with all interested and especially those responsible for future healthcare decision making. With the present paper, international and heterogenous multidisciplinary panel of very differentiated people would like to share global experiences and lessons with all interested and especially those responsible for future healthcare decision making.
Published: 2021

30. 2020 WSES guidelines for the detection and management of bile duct injury during cholecystectomy

Author: De'Angelis, N., Catena, F., Memeo, R., Coccolini, F., Martínez-Pérez, A., Romeo, O.M., Simone, B. De, Saverio, S. Di, Brustia, R., Rhaiem, R., Piardi, T., Conticchio, M., Marchegiani, F., Beghdadi, N., Abu-Zidan, F.M., Alikhanov, R., Allard, M.A., Allievi, N., Amaddeo, G., Ansaloni, L., Andersson, R., Andolfi, E., Azfar, M., Bala, M., Benkabbou, A., Ben-Ishay, O., Bianchi, G., Biffl, W.L., Brunetti, F., Carra, M.C., Casanova, D., Celentano, V., Ceresoli, M., Chiara, O., Cimbanassi, S., Bini, R., Coimbra, R., de'Angelis, G. Luigi, Decembrino, F., Palma, A., Reuver, P.R. de, Domingo, C., Cotsoglou, C., Ferrero, A., Fraga, G.P., Gaiani, F., Gheza, F., Gurrado, A., Harrison, E., Henriquez, A., Hofmeyr, S., Iadarola, R., Kashuk, J.L., Kianmanesh, R., Kirkpatrick, A.W., Kluger, Y., Landi, F., Langella, S., Lapointe, R., Roy, B., Luciani, A., Machado, F., Maggi, U., Maier, R.V., Mefire, A.C., Hiramatsu, K., Ordoñez, C., Patrizi, F., Planells, M., Peitzman, A.B., Pekolj, J., Perdigao, F., Pereira, B.M., Pessaux, P., Pisano, M., Puyana, J.C., Rizoli, S., Portigliotti, L., Romito, R., Sakakushev, B., Sanei, B., Scatton, O., Serradilla-Martin, M., Schneck, A.S., Sissoko, M.L., Sobhani, I., Broek, R.P. Ten, Testini, M., Valinas, R., Veloudis, G., Vitali, G.C., Weber, D., Zorcolo, L., Giuliante, F., Gavriilidis, P., Fuks, D., Sommacale, D., De'Angelis, N., Catena, F., Memeo, R., Coccolini, F., Martínez-Pérez, A., Romeo, O.M., Simone, B. De, Saverio, S. Di, Brustia, R., Rhaiem, R., Piardi, T., Conticchio, M., Marchegiani, F., Beghdadi, N., Abu-Zidan, F.M., Alikhanov, R., Allard, M.A., Allievi, N., Amaddeo, G., Ansaloni, L., Andersson, R., Andolfi, E., Azfar, M., Bala, M., Benkabbou, A., Ben-Ishay, O., Bianchi, G., Biffl, W.L., Brunetti, F., Carra, M.C., Casanova, D., Celentano, V., Ceresoli, M., Chiara, O., Cimbanassi, S., Bini, R., Coimbra, R., de'Angelis, G. Luigi, Decembrino, F., Palma, A., Reuver, P.R. de, Domingo, C., Cotsoglou, C., Ferrero, A., Fraga, G.P., Gaiani, F., Gheza, F., Gurrado, A., Harrison, E., Henriquez, A., Hofmeyr, S., Iadarola, R., Kashuk, J.L., Kianmanesh, R., Kirkpatrick, A.W., Kluger, Y., Landi, F., Langella, S., Lapointe, R., Roy, B., Luciani, A., Machado, F., Maggi, U., Maier, R.V., Mefire, A.C., Hiramatsu, K., Ordoñez, C., Patrizi, F., Planells, M., Peitzman, A.B., Pekolj, J., Perdigao, F., Pereira, B.M., Pessaux, P., Pisano, M., Puyana, J.C., Rizoli, S., Portigliotti, L., Romito, R., Sakakushev, B., Sanei, B., Scatton, O., Serradilla-Martin, M., Schneck, A.S., Sissoko, M.L., Sobhani, I., Broek, R.P. Ten, Testini, M., Valinas, R., Veloudis, G., Vitali, G.C., Weber, D., Zorcolo, L., Giuliante, F., Gavriilidis, P., Fuks, D., and Sommacale, D.
Abstract: Contains fulltext : 238974.pdf (Publisher’s version ) (Open Access), Bile duct injury (BDI) is a dangerous complication of cholecystectomy, with significant postoperative sequelae for the patient in terms of morbidity, mortality, and long-term quality of life. BDIs have an estimated incidence of 0.4-1.5%, but considering the number of cholecystectomies performed worldwide, mostly by laparoscopy, surgeons must be prepared to manage this surgical challenge. Most BDIs are recognized either during the procedure or in the immediate postoperative period. However, some BDIs may be discovered later during the postoperative period, and this may translate to delayed or inappropriate treatments. Providing a specific diagnosis and a precise description of the BDI will expedite the decision-making process and increase the chance of treatment success. Subsequently, the choice and timing of the appropriate reconstructive strategy have a critical role in long-term prognosis. Currently, a wide spectrum of multidisciplinary interventions with different degrees of invasiveness is indicated for BDI management. These World Society of Emergency Surgery (WSES) guidelines have been produced following an exhaustive review of the current literature and an international expert panel discussion with the aim of providing evidence-based recommendations to facilitate and standardize the detection and management of BDIs during cholecystectomy. In particular, the 2020 WSES guidelines cover the following key aspects: (1) strategies to minimize the risk of BDI during cholecystectomy; (2) BDI rates in general surgery units and review of surgical practice; (3) how to classify, stage, and report BDI once detected; (4) how to manage an intraoperatively detected BDI; (5) indications for antibiotic treatment; (6) indications for clinical, biochemical, and imaging investigations for suspected BDI; and (7) how to manage a postoperatively detected BDI.
Published: 2021

31. Hemithyroidectomy versus total thyroidectomy in the intermediate-risk differentiated thyroid cancer: the Italian Societies of Endocrine Surgeons and Surgical Oncology Multicentric Study

Author: Dobrinja, C., Samardzic, N., Giudici, F., Raffaelli, Marco, De Crea, Carmela, Sessa, Luca, Docimo, G., Ansaldo, G. L., Minuto, M., Varaldo, E., Dionigi, G., Spiezia, S., Boniardi, M., Pauna, I., De Pasquale, L., Testini, M., Gurrado, A., Pasculli, A., Pezzolla, A., Lattarulo, S., Calo, P. G., Graceffa, G., Massara, A., Docimo, L., Ruggiero, R., Parmeggiani, D., Iacobone, M., Innaro, N., Lombardi, Celestino Pio, de Manzini, N., Raffaelli M. (ORCID:0000-0002-1259-2491), De Crea C. (ORCID:0000-0002-7303-9657), Sessa L., Lombardi C. P. (ORCID:0000-0001-8910-6693), Dobrinja, C., Samardzic, N., Giudici, F., Raffaelli, Marco, De Crea, Carmela, Sessa, Luca, Docimo, G., Ansaldo, G. L., Minuto, M., Varaldo, E., Dionigi, G., Spiezia, S., Boniardi, M., Pauna, I., De Pasquale, L., Testini, M., Gurrado, A., Pasculli, A., Pezzolla, A., Lattarulo, S., Calo, P. G., Graceffa, G., Massara, A., Docimo, L., Ruggiero, R., Parmeggiani, D., Iacobone, M., Innaro, N., Lombardi, Celestino Pio, de Manzini, N., Raffaelli M. (ORCID:0000-0002-1259-2491), De Crea C. (ORCID:0000-0002-7303-9657), Sessa L., and Lombardi C. P. (ORCID:0000-0001-8910-6693)
Abstract: The surgical treatment of the intermediate-risk DTC (1–4 cm) remains still controversial. We analyzed the current practice in Italy regarding the surgical management of intermediate-risk unilateral DTC to evaluate risk factors for recurrence and to identify a group of patients to whom propose a total thyroidectomy (TT) vs. hemithyroidectomy (HT). Among 1896 patients operated for thyroid cancer between January 2017 and December 2019, we evaluated 564 (29.7%) patients with unilateral intermediate-risk DTC (1–4 cm) without contralateral nodular lesions on the preoperative exams, chronic autoimmune thyroiditis, familiarity or radiance exposure. Data were collected retrospectively from the clinical register from 16 referral centers. The patients were followed for at least 14 months (median time 29.21 months). In our cohort 499 patients (88.4%) underwent total thyroidectomy whereas 65 patients (11.6%) underwent hemithyroidectomy. 151 (26.8%) patients had a multifocal DTC of whom 57 (10.1%) were bilateral. 21/66 (32.3%) patients were reoperated within 2 months from the first intervention (completion thyroidectomy). Three patients (3/564) developed regional lymph node recurrence 2 years after surgery and required a lymph nodal neck dissection. The single factor related to the risk of reoperation was the histological diameter (HR = 1.05 (1.00–1-09), p = 0.026). Risk stratification is the key to differentiating treatment options and achieving better outcomes. According to the present study, tumor diameter is a strong predictive risk factor to proper choose initial surgical management for intermediate‐risk DTC.
Published: 2021

32. International Variation in Surgical Practices in Units Performing Oesophagectomy for Oesophageal Cancer: A Unit Survey from the Oesophago-Gastric Anastomosis Audit (OGAA)

Author: Bundred, J. R., Kamarajah, S. K., Siaw-Acheampong, K., Nepogodiev, D., Jefferies, B., Singh, P., Evans, R., Griffiths, E. A., Alderson, D., Gossage, J., Mckay, S., Mohamed, I., van Hillegersberg, R., Vohra, R., Wanigsooriya, K., Whitehouse, T., Bagajevas, A., Bekele, A., Blanco-Colino, R., Da Roit, A., El Kafsi-Mawley, J., Gjata, A., Gockel, I., Castro, R. G., Harustiak, T., Hsu, P. -K., Isik, A., Kechagias, A., Kennedy, A., Kidane, B., Mahendran, H. A., Mejia, L., Moreno, J. I., Negoi, I., Santiago, A. J., Sayyed, R., Schneider, P., Soares, A. S., Sousa, M., Takeda, F. R., Vanstraten, S., Wallner, B., Wijnhoven, B., Achiam, M., Agustin, T., Akbar, A., Al-Bahrani, A., Al-Khyatt, W., Albertsmeier, M., Alghunaim, E., Alkhaffaf, B., Allum, W., Am, F., Andreollo, N., Arndt, A., Babor, R., Barbosa, J., Bardini, R., Beardsmore, D., Beban, G., Bernardes, A., Berrisford, R., Bianchi, A., Bjelovic, M., Boddy, A., Bolca, C., Bonavina, L., Bryce, G., Byrom, R., Casaca, R., Chan, D., Charalabopoulos, A., Cheong, E., Ciotola, F., Colak, E., Collins, C., Constantinoiu, S., Costa, R., Dahlke, M., Darling, G., Dawas, K., de Manzoni, G., Denewer, A., Devadas, M., Dexter, S., Dikinis, S., Dimitrios, T., Dolan, J., Duong, C., Egberts, J. -H., Elgharably, Y., Elhadi, M., Elmahi, S., Farias, F. A., Fekaj, E., Fernandez, J., Forshaw, M., Freire, J., French, D., Gacevski, G., Gaedcke, J., Gananadha, S., Gijon, M. M., Gokhale, J., Gordon, A., Grimminger, P., Guevara, R., Guner, A., Gutknecht, S., Mahmoodzadeh, H., Halldestam, I., Hedberg, J., Heisterkamp, J., Higgs, S., Hii, M., Hindmarsh, A., Hoppner, J., Isaza, A., Izbicki, J., Jacobs, R., Jain, P., Johansson, J., Johnston, B., Kafsi, J., Kassa, S., Kelty, C., Khan, I., Khoo, D., Khyatt, S., Kjaer, D., Korkolis, D., Kreuser, N., Larsen, M., Lau, P., Leite, J., Lewis, W., Liakakos, T., Loureiro, C., Mahendran, A., Maynard, N., Mcgregor, R., Mcnally, S., Medina-Franco, H., Meguid, R., Melhado, R., Mercer, S., Migliore, M., Mingol, F., Mogoanta, S., Mohri, Y., Monig, S., Moreno, J., Motas, N., Murphy, T., Naqi, S., Ni, R., Niazi, S., Oglesby, S., Okonta, K., Ortiz, S. R., Pal, K., Palazzo, F., Pascher, A., Pascual, M., Pata, G., Pera, M., Puig, S., Ramirez, J., Raptis, D., Rasanen, J., Reim, D., Reynolds, J., Robb, W., Robertson, K., Rosero, G., Rosman, C., Rossaak, J., Saarnio, J., Santiago, A., Schiesser, M., Scurtu, R. -R., Sekhniaidze, D., Sevinc, B., Skipworth, R., So, J., Trugeda, M. S., Syed, A., Takahashi, A. M. L., Takeda, F., Talbot, M., Tareen, M., Terashima, M., Testini, M., Tewari, N., Tez, M., Thomas, M., Tirnaksiz, M., Tonini, V., C. -C., Tu, Turner, P., Underwood, T., Uzair, A., Vallve-Bernal, M., Valmasoni, M., Vicente, C., Videira, J. F., Viswanath, Y., Weindelmayer, J., White, R., Wigle, D., Wilkerson, P., Wills, V., Zacharakis, E., Zuluaga, M., Surgery, Moenig, Stefan Paul, Bundred J.R., Kamarajah S.K., Siaw-Acheampong K., Nepogodiev D., Jefferies B., Singh P., Evans R., Griffiths E.A., Alderson D., Gossage J., McKay S., Mohamed I., van Hillegersberg R., Vohra R., Wanigsooriya K., Whitehouse T., Bagajevas A., Bekele A., Blanco-Colino R., Da Roit A., El Kafsi-Mawley J., Gjata A., Gockel I., Castro R.G., Harustiak T., Hsu P.-K., Isik A., Kechagias A., Kennedy A., Kidane B., Mahendran H.A., Mejia L., Moreno J.I., Negoi I., Santiago A.J., Sayyed R., Schneider P., Soares A.S., Sousa M., Takeda F.R., Vanstraten S., Wallner B., Wijnhoven B., Achiam M., Agustin T., Akbar A., Al-Bahrani A., Al-Khyatt W., Albertsmeier M., Alghunaim E., Alkhaffaf B., Allum W., Am F., Andreollo N., Arndt A., Babor R., Barbosa J., Bardini R., Beardsmore D., Beban G., Bernardes A., Berrisford R., Bianchi A., Bjelovic M., Boddy A., Bolca C., Bonavina L., Bryce G., Byrom R., Casaca R., Chan D., Charalabopoulos A., Cheong E., Ciotola F., Colak E., Collins C., Constantinoiu S., Costa R., Dahlke M., Darling G., Dawas K., de Manzoni G., Denewer A., Devadas M., Dexter S., Dikinis S., Dimitrios T., Dolan J., Duong C., Egberts J.-H., Elgharably Y., Elhadi M., Elmahi S., Farias F.A., Fekaj E., Fernandez J., Forshaw M., Freire J., French D., Gacevski G., Gaedcke J., Gananadha S., Gijon M.M., Gokhale J., Gordon A., Grimminger P., Guevara R., Guner A., Gutknecht S., Mahmoodzadeh H., Halldestam I., Hedberg J., Heisterkamp J., Higgs S., Hii M., Hindmarsh A., Hoppner J., Isaza A., Izbicki J., Jacobs R., Jain P., Johansson J., Johnston B., Kafsi J., Kassa S., Kelty C., Khan I., Khoo D., Khyatt S., Kjaer D., Korkolis D., Kreuser N., Larsen M., Lau P., Leite J., Lewis W., Liakakos T., Loureiro C., Mahendran A., Maynard N., Mcgregor R., Mcnally S., Medina-Franco H., Meguid R., Melhado R., Mercer S., Migliore M., Mingol F., Mogoanta S., Mohri Y., Monig S., Moreno J., Motas N., Murphy T., Naqi S., Ni R., Niazi S., Oglesby S., Okonta K., Ortiz S.R., Pal K., Palazzo F., Pascher A., Pascual M., Pata G., Pera M., Puig S., Ramirez J., Raptis D., Rasanen J., Reim D., Reynolds J., Robb W., Robertson K., Rosero G., Rosman C., Rossaak J., Saarnio J., Santiago A., Schiesser M., Scurtu R.-R., Sekhniaidze D., Sevinc B., Skipworth R., So J., Trugeda M.S., Syed A., Takahashi A.M.L., Takeda F., Talbot M., Tareen M., Terashima M., Testini M., Tewari N., Tez M., Thomas M., Tirnaksiz M., Tonini V., Tu C.-C., Turner P., Underwood T., Uzair A., Vallve-Bernal M., Valmasoni M., Vicente C., Videira J.F., Viswanath Y., Weindelmayer J., White R., Wigle D., Wilkerson P., Wills V., Zacharakis E., and Zuluaga M.
Subjects: Leak, medicine.medical_specialty, Internationality, Oesophagectomy , Oesophageal Cancer: Oesophago-Gastric Anastomosis, complications, Esophageal Neoplasms, Anastomosis, Anastomotic Leak, Audit, Anastomosis, Surgical, Developed Countries, Developing Countries, Drainage, Esophagectomy, Hospital Units, Humans, Stents, Surveys and Questionnaires, Enhanced Recovery After Surgery, Unit (housing), 03 medical and health sciences, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Anastomotic leaks, Surgical, medicine, Journal Article, Response rate (survey), medicine.diagnostic_test, ddc:617, business.industry, General surgery, Cancer, Interventional radiology, medicine.disease, 030220 oncology & carcinogenesis, 030211 gastroenterology & hepatology, Surgery, business
Abstract: Background: Anastomotic leaks are associated with significant risk of morbidity, mortality and treatment costs after oesophagectomy. The aim of this study was to evaluate international variation in unit-level clinical practice and resource availability for the prevention and management of anastomotic leak following oesophagectomy.Method: The Oesophago-Gastric Anastomosis Audit (OGAA) is an international research collaboration focussed on improving the care and outcomes of patients undergoing oesophagectomy. Any unit performing oesophagectomy worldwide can register to participate in OGAA studies. An online unit survey was developed and disseminated to lead surgeons at each unit registered to participate in OGAA. High-income country (HIC) and low/middle-income country (LMIC) were defined according to the World Bank whilst unit volume were defined as < 20 versus 20-59 versus ≥60 cases/year in the unit.Results: Responses were received from 141 units, a 77% (141/182) response rate. Median annual oesophagectomy caseload was reported to be 26 (inter-quartile range 12-50). Only 48% (68/141) and 22% (31/141) of units had an Enhanced Recovery After Surgery (ERAS) program and ERAS nurse, respectively. HIC units had significantly higher rates of stapled anastomosis compared to LMIC units (66 vs 31%, p = 0.005). Routine post-operative contrast-swallow anastomotic assessment was performed in 52% (73/141) units. Stent placement and interventional radiology drainage for anastomotic leak management were more commonly available in HICs than LMICs (99 vs 59%, p < 0.001 and 99 vs 83%, p < 0.001).Conclusions: This international survey highlighted variation in surgical technique and management of anastomotic leak based on case volume and country income level. Further research is needed to understand the impact of this variation on patient outcomes.
Published: 2019
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33. A Combined Open and Laparoscopic Technique for the Treatment of Umbilical Hernia: Retrospective Review of a Consecutive Series of Patients

Author: Prete, F. P., Gurrado, A., Pasculli, A., Sgaramella, L. I., Catalano, G., Sallustio, P. N. M., Carbotta, G., Ialongo, P., Giuseppe Cavallaro, and Testini, M.
Subjects: umbilical hernia repair, Postoperative Complications, umbilical hernia repair, intraperitoneal mesh positioning, laparoscopy, Recurrence, Humans, Laparoscopy, Surgical Mesh, intraperitoneal mesh positioning, Hernia, Umbilical, Herniorrhaphy, Retrospective Studies
Abstract: To investigate the safety and outcomes of laparoscopic control of intraperitoneal mesh positioning in open umbilical hernia repair.This study is a retrospective review of a series of adult patients with uncomplicated umbilical hernia who underwent elective open repair with a self-expanding patch with laparoscopic control from March 2011 to December 2018. The adequacy of mesh positioning was inspected with a 5-mm 30° scope in the left flank. The primary endpoint was recurrence. Secondary endpoints were rate of mesh repositioning, intraoperative complications and time, length of stay and postoperative pain.Thirty-five patients underwent open inlay repair of primary umbilical hernia with laparoscopic control. Six patients (17.1%) were obese. The mean operating time was 63.3 min. The mean defect size was 2.6 cm (0.6-5) and the mean mesh overlap was 3.2cm (2.2-4.5). There were no intraoperative complications. Laparoscopic control required mesh repositioning in 5 cases (14.3%). The median length of stay was 2 days. Perioperative complications were recorded in three cases (8.6%): one seroma and two serous wound discharge (Clavien-Dindo I). The recurrence rate was 2.9% (1 case) at a median follow-up of 60 months. BMI30 was associated with a higher rate of intraoperative mesh repositioning (p=0.001). Non-reabsorbable mesh and COPD were associated with a higher incidence of postoperative complications (p=0.043). Postoperative pain scores were consistently at mild levels, with no statistically significant differences between patients who had their mesh repositioned and those who had not.Laparoscopic control of mesh positioning is a safe addition to open inlay umbilical hernia repair and enables the accurate verification of correct mesh deployment with low complication and recurrence rates.
Published: 2020

34. Robotic‐assisted treatment of intestinal malrotation in an adult man – a video vignette

Author: Pasculli, A., primary, Gurrado, A., additional, Vittore, F., additional, De Luca, G. M., additional, Sammarco, A., additional, and Testini, M., additional
Published: 2020
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35. Bile duct ligation and early biochemical damage of the liver. An experimental model in the rat: 1004

Author: Lissidini, G., Gurrado, A., Grattagliano, I., Poli, E., Valentini, M. F., Piccinni, G., Portincasa, P., and Testini, M.
Published: 2010

36. Parathyroid hormone-related peptide and primary hyperparathyroidism: 34

Author: Gurrado, A., Lissidini, G., Poli, E., Ruggiero, L., Piccinni, G., and Testini, M.
Published: 2010

37. Goal-directed haemodynamic therapy and gastrointestinal complications in major surgery: a meta-analysis of randomized controlled trials

Author: Giglio, M T, Marucci, M, Testini, M, and Brienza, N
Published: 2009

38. Invasive apocrine carcinoma of the breast: myth or fact?

Author: Gurrado, A., Girardi, A., Moschetta, M., Serio, G., Marzullo, A., Telegrafo, M., Fragassi, F., Ferraro, V., Testini, M., and Ferraro, Valentina
Subjects: medicine.medical_specialty, business.industry, Carcinoma, Breast Neoplasms, Apocrine Carcinoma, apocrine carcinoma, Dermatology, Sweat Gland Neoplasms, Apocrine Glands, breast cancer, Oncology, Internal Medicine, medicine, Humans, Female, Surgery, Breast, business
Published: 2019

39. Treatment of chronic pilonidal sinus with local anaesthesia: a randomized trial of closed compared with open technique

Author: Testini, M., Piccinni, G., Miniello, S., Venere, B. Di, Lissidini, G., Nicolardi, V., and Bonomo, G. M.
Published: 2001

40. IPOD Study: Management of Acute Left Colonic Diverticulitis in Italian Surgical Departments

Author: Sartelli, M., Binda, G. A., Brandara, F., Borasi, A., Feroci, F., Vadala, S., Labricciosa, F. M., Birindelli, A., Luridiana, G., Coccolini, F., Di Saverio, S., Catena, F., Ansaloni, L., Campanile, F. C., Agresta, F., Piazza, D., Anania, G., Caproli, E., Gasparrini, M., Bordoni, P., Lucchi, A., Scabini, S., Picardi, B., Sarro, G., Piccinini, A., Bedin, N., Bussotti, A., De Angelis, R., Baiocchi, G. L., Andreotti, A., Cillara, N., Petronio, B., Grimaldi, S., Biancafarina, A., Somenzi, D., Costanzi, A., Marvaso, A., Canfora, A., Vasquez, G., Chiodo, C., Nano, M., Cavicchi, A., Ruffato, A., Baccari, P., Polastri, R., Marsanic, P., Portale, G., Gordini, L., Abongwa, H. K., Pili, M., Turati, L., Nusca, V., Guercioni, G., Delogu, L. A., Robustelli, U., Piras, D., Serventi, F., Prando, D., Brunelli, A., Zani, B., Pintaldi, S., Verzelli, A., Mulas, S., Confalonieri, G., Spagni, G., Crucitti, Antonio, Sagnotta, A., Fiume, S., Balestra, F., Gatti, M., Eugeni, E., Carraro, A., Genna, M., Taglietti, L., Azzinnaro, A., Ferfoglia, S., Miranda, G., Tirone, G., Luparello, P., Berti, S., Tutino, R., De Manzoni Garberini, A., Roscio, F., Maglione, V., Podda, M., Ioia, G., Cantore, F., Mazzalai, F., Cortesi, F., Arcuri, G., Bellanova, G., Beltramo, M., Chessa, A., Coppola, M., Gozzo, D., Harbi, A., Minciotti, E., Pata, F., Pinna, G., Testini, M., Vanella, S., Crucitti A. (ORCID:0000-0003-3496-4185), Sartelli, M., Binda, G. A., Brandara, F., Borasi, A., Feroci, F., Vadala, S., Labricciosa, F. M., Birindelli, A., Luridiana, G., Coccolini, F., Di Saverio, S., Catena, F., Ansaloni, L., Campanile, F. C., Agresta, F., Piazza, D., Anania, G., Caproli, E., Gasparrini, M., Bordoni, P., Lucchi, A., Scabini, S., Picardi, B., Sarro, G., Piccinini, A., Bedin, N., Bussotti, A., De Angelis, R., Baiocchi, G. L., Andreotti, A., Cillara, N., Petronio, B., Grimaldi, S., Biancafarina, A., Somenzi, D., Costanzi, A., Marvaso, A., Canfora, A., Vasquez, G., Chiodo, C., Nano, M., Cavicchi, A., Ruffato, A., Baccari, P., Polastri, R., Marsanic, P., Portale, G., Gordini, L., Abongwa, H. K., Pili, M., Turati, L., Nusca, V., Guercioni, G., Delogu, L. A., Robustelli, U., Piras, D., Serventi, F., Prando, D., Brunelli, A., Zani, B., Pintaldi, S., Verzelli, A., Mulas, S., Confalonieri, G., Spagni, G., Crucitti, Antonio, Sagnotta, A., Fiume, S., Balestra, F., Gatti, M., Eugeni, E., Carraro, A., Genna, M., Taglietti, L., Azzinnaro, A., Ferfoglia, S., Miranda, G., Tirone, G., Luparello, P., Berti, S., Tutino, R., De Manzoni Garberini, A., Roscio, F., Maglione, V., Podda, M., Ioia, G., Cantore, F., Mazzalai, F., Cortesi, F., Arcuri, G., Bellanova, G., Beltramo, M., Chessa, A., Coppola, M., Gozzo, D., Harbi, A., Minciotti, E., Pata, F., Pinna, G., Testini, M., Vanella, S., and Crucitti A. (ORCID:0000-0003-3496-4185)
Abstract: Background: In recent years, the emergency management of acute left colonic diverticulitis (ALCD) has evolved dramatically despite lack of strong evidence. As a consequence, management strategies are frequently guided by surgeon’s personal preference, rather than by scientific evidence. The primary aim of IPOD study (Italian Prospective Observational Diverticulitis study) is to describe both the diagnostic and treatment profiles of patients with ALCD in the Italian surgical departments. Methods: IPOD study is a prospective observational study performed during a 6-month period (from April 1 2015 to September 1 2015) and including 89 Italian surgical departments. All consecutive patients with suspected clinical diagnosis of ALCD confirmed by imaging and seen by a surgeon were included in the study. The study was promoted by the Italian Society of Hospital Surgeons and the World Society of Emergency Surgery Italian chapter. Results: Eleven hundred and twenty-five patients with a median age of 62 years [interquartile range (IQR), 51–74] were enrolled in the IPOD study. One thousand and fifty-four (93.7%) patients were hospitalized with a median duration of hospitalization of 7 days (IQR 5–10). Eight hundred and twenty-eight patients (73.6%) underwent medical treatment alone, 13 patients had percutaneous drainage (1.2%), and the other 284 (25.2%) patients underwent surgery as first treatment. Among 121 patients having diffuse peritonitis, 71 (58.7%) underwent Hartmann’s resection. However, the Hartmann’s resection was used even in patients with lower stages of ALCD (36/479; 7.5%) where other treatment options could be more adequate. Conclusions: The IPOD study demonstrates that in the Italian surgical departments treatment strategies for ALCD are often guided by the surgeon’s personal preference.
Published: 2017

41. Diagnostic, therapeutic and health-care management protocol in thyroid surgery: a position statement of the Italian Association of Endocrine Surgery Units (U.E.C. CLUB).

Author: Rosato, L, De Crea, Carmela, Bellantone, R, Brandi, Ml, De Toma, Giorgio, Filetti, S, Miccoli, P, Pacini, F, Pelizzo, Mr, Pontecorvi, Alfredo, Avenia, N, De Pasquale, Tiziana Maria Angela, Chiofalo, Mg, Gurrado, A, Innaro, N, Lavalle, Angela, Lombardi, C, Marini, Pl, Mondini, G, Mullineris, B, Pezzullo, Angelo Maria, Raffaelli, Marco, Testini, M, De Palma, M., De Crea C (ORCID:0000-0002-7303-9657), De Toma G, Pontecorvi A (ORCID:0000-0003-0570-6865), De Pasquale L, La Valle G, Pezzullo L (ORCID:0000-0002-8252-4654), Raffaelli M (ORCID:0000-0002-1259-2491), Rosato, L, De Crea, Carmela, Bellantone, R, Brandi, Ml, De Toma, Giorgio, Filetti, S, Miccoli, P, Pacini, F, Pelizzo, Mr, Pontecorvi, Alfredo, Avenia, N, De Pasquale, Tiziana Maria Angela, Chiofalo, Mg, Gurrado, A, Innaro, N, Lavalle, Angela, Lombardi, C, Marini, Pl, Mondini, G, Mullineris, B, Pezzullo, Angelo Maria, Raffaelli, Marco, Testini, M, De Palma, M., De Crea C (ORCID:0000-0002-7303-9657), De Toma G, Pontecorvi A (ORCID:0000-0003-0570-6865), De Pasquale L, La Valle G, Pezzullo L (ORCID:0000-0002-8252-4654), and Raffaelli M (ORCID:0000-0002-1259-2491)
Abstract: PURPOSE: The diagnostic, therapeutic and health-care management protocol (Protocollo Gestionale Diagnostico-Terapeutico-Assistenziale, PDTA) by the Association of the Italian Endocrine Surgery Units (U.E.C. CLUB) aims to help treat the patient in a topical, rational way that can be shared by health-care professionals. METHODS: This fourth consensus conference involved: a selected group of experts in the preliminary phase; all members, via e-mail, in the elaboration phase; all the participants of the XI National Congress of the U.E.C. CLUB held in Naples in the final phase. The following were examined: diagnostic pathway and clinical evaluation; mode of admission and waiting time; therapeutic pathway (patient preparation for surgery, surgical treatment, postoperative management, management of major complications); hospital discharge and patient information; outpatient care and follow-up. RESULTS: A clear and concise style was adopted to illustrate the reasons and scientific rationales behind behaviors and to provide health-care professionals with a guide as complete as possible on who, when, how and why to act. The protocol is meant to help the surgeon to treat the patient in a topical, rational way that can be shared by health-care professionals, but without influencing in any way the physician-patient relationship, which is based on trust and clinical judgment in each individual case. CONCLUSIONS: The PDTA in thyroid surgery approved by the fourth consensus conference (June 2015) is the official PDTA of U.E.C. CLUB.
Published: 2016

42. Emergency pancreaticoduodenectomy for non-traumatic duodenopancreatic disease

Author: Testini, M., primary, Prete, F.P., additional, Pasculli, A., additional, Piccinni, G., additional, and Prete, F., additional
Published: 2016
Full Text: View/download PDF

43. Multiple pancreaticoduodenal penetrating gunshot trauma evolving into acute necrotizing pancreatitis. A combined surgical and minimally invasive approach

Author: Pasculli, A., primary, Pedote, P., additional, Gurrado, A., additional, Lissidini, G., additional, and Testini, M., additional
Published: 2016
Full Text: View/download PDF

44. Diagnostic, therapeutic and health-care management protocol in thyroid surgery: a position statement of the Italian Association of Endocrine Surgery Units (U.E.C. CLUB)

Author: Rosato, Livia, De Crea, Carmela, Bellantone, Rocco Domenico Alfonso, Brandi, M. L., De Toma, Giorgio, Filetti, S., Miccoli, P., Pacini, F., Pelizzo, M. R., Pontecorvi, Alfredo, Avenia, N., De Pasquale, L., Chiofalo, M. G., Gurrado, A., Innaro, N., La Valle, G., Lombardi, Celestino Pio, Marini, P. L., Mondini, G., Mullineris, B., Pezzullo, L., Raffaelli, Marco, Testini, M., De Palma, M., De Crea, Carmela (ORCID:0000-0002-7303-9657), Bellantone, Rocco Domenico Alfonso (ORCID:0000-0002-0844-3469), Pontecorvi, Alfredo (ORCID:0000-0003-0570-6865), Lombardi, Celestino Pio (ORCID:0000-0001-8910-6693), Raffaelli, Marco (ORCID:0000-0002-1259-2491), Rosato, Livia, De Crea, Carmela, Bellantone, Rocco Domenico Alfonso, Brandi, M. L., De Toma, Giorgio, Filetti, S., Miccoli, P., Pacini, F., Pelizzo, M. R., Pontecorvi, Alfredo, Avenia, N., De Pasquale, L., Chiofalo, M. G., Gurrado, A., Innaro, N., La Valle, G., Lombardi, Celestino Pio, Marini, P. L., Mondini, G., Mullineris, B., Pezzullo, L., Raffaelli, Marco, Testini, M., De Palma, M., De Crea, Carmela (ORCID:0000-0002-7303-9657), Bellantone, Rocco Domenico Alfonso (ORCID:0000-0002-0844-3469), Pontecorvi, Alfredo (ORCID:0000-0003-0570-6865), Lombardi, Celestino Pio (ORCID:0000-0001-8910-6693), and Raffaelli, Marco (ORCID:0000-0002-1259-2491)
Abstract: Purpose: The diagnostic, therapeutic and health-care management protocol (Protocollo Gestionale Diagnostico-Terapeutico-Assistenziale, PDTA) by the Association of the Italian Endocrine Surgery Units (U.E.C. CLUB) aims to help treat the patient in a topical, rational way that can be shared by health-care professionals. Methods: This fourth consensus conference involved: a selected group of experts in the preliminary phase; all members, via e-mail, in the elaboration phase; all the participants of the XI National Congress of the U.E.C. CLUB held in Naples in the final phase. The following were examined: diagnostic pathway and clinical evaluation; mode of admission and waiting time; therapeutic pathway (patient preparation for surgery, surgical treatment, postoperative management, management of major complications); hospital discharge and patient information; outpatient care and follow-up. Results: A clear and concise style was adopted to illustrate the reasons and scientific rationales behind behaviors and to provide health-care professionals with a guide as complete as possible on who, when, how and why to act. The protocol is meant to help the surgeon to treat the patient in a topical, rational way that can be shared by health-care professionals, but without influencing in any way the physician–patient relationship, which is based on trust and clinical judgment in each individual case. Conclusions: The PDTA in thyroid surgery approved by the fourth consensus conference (June 2015) is the official PDTA of U.E.C. CLUB.
Published: 2015

45. Diagnostic, therapeutic and healthcare management protocols in thyroid surgery: 3rd Consensus Conference of the Italian Association of Endocrine Surgery Units (U.E.C. CLUB)

Author: Rosato L, De Toma G, Bellantone R, Avenia N, Cavallaro G, Dobrinja C, Maria Grazia Chiofalo, De Crea C, De Palma M, Gasparri G, Gurrado A, Lombardi C, Miccoli P, Mullineris B, Pg, Nasi, Pelizzo MR, Pezzullo L, Perigli G, Testini M, and Associazione delle Unità di Endocrinochirurgia Italiana
Subjects: Parathyroidectomy, Hyperparathyroidism, Preoperative work up, protocols, Postoperative management, Hyperparathyroidism, Parathyroid disease, Parathyroidectomy, Postoperative management, Preoperative work up, Thyroid Diseases, thyroid, Diagnostic, therapeutic, management, surgery, Clinical Protocols, Thyroidectomy, Parathyroid disease, Humans
Published: 2012

46. Does mediastinal extension of the goiter increase morbidity of total thyroidectomy?A multicenter study of 19662 patients

Author: Testini, M, Gurrado, A, Avenia, N, Bellantone, Rocco Domenico Alfonso, Biondi, A, Brazzarola, P, Calzolari, F, Cavallaro, G, De Toma, G, Guida, P, Lissidini, G, Loizzi, M, Lombardi, Celestino Pio, Piccinni, G, Portincasa, P, Rosato, L, Sartori, N, Zugni, C, and Basile, F.
Subjects: goiter, Settore MED/18 - CHIRURGIA GENERALE, thyroidectomy
Published: 2011

47. Protocolli gestionali diagnostico-terapeutico-assistenziali in chirurgia tiroidea. II Consensus Conference dell’Associazione delle Unita’ di Endocrinochirurgia Italiane (Club delle UEC)

Author: Rosato, L., Miccoli, P., Pinchera, A., Lombardi, G., Romano, M., Avenia, Nicola, Bastagli, A., Bellantone, R., De Palma, M., de Toma, G., Gasparri, G., Lampugnani, R., Marini, C., Nasi, P., Pelizzo, M., Pezzullo, L., Piccoli, M., and Testini, M.
Published: 2009

48. Diagnostic, therapeutic and healthcare management protocols in thyroid surgery. 2nd Consensus Conference (U.E.C. CLUB)

Author: Rosato, L, Miccoli, Paolo, Pinchera, Aldo, Lombardi, G, Romano, M, Avenia, N, Bastagli, A, Bellantone, R, DE PALMA, M, DE TOMA, G, Gasparri, GIAN MARIA, Lampugnani, R, Marini, Pl, Nasi, Pg, Pellizzo, Mr, Pezzullo, L, Piccoli, M, and Testini, M.
Subjects: diagnostic protocol, Settore MED/18 - CHIRURGIA GENERALE, thyroid surgery
Published: 2009

49. PROTOCOLLI GESTIONALI DIAGNOSTICO-TERAPEUTICO-ASSITENZIALI IN CHIRURGIA TIROIDEA

Author: Rosato, L, Miccoli, P, Pinchera, A, Lombardi, G, Romano, M, Avenia, N, Bastagli, A, Bellantone, R, DE PALMA, M, DE TOMA, Giorgio, Gasparri, G, Lampugnani, R, Marini, Pl, Nasi, Pg, Pelizzo, Mr, Pezzullo, L, Piccoli, M, and Testini, M.
Published: 2009

50. Protocolli Gestionali Diagnostico-Terapeutici- Assistenziali in Chiruriga Tiroidea. 2 feminine Consensus Conference

Author: Rosato, L., Miccoli, P., Pinchera, A., Lombardi, G., Romano, M., Avenia, N., Bastagli, A., Bellantone, R., De Palma, M., de Toma, G., Gasparri, Guido, Lampugnani, R., Marini, P. L., Nasi, P. G., Pellizzo, M. R., Pezzullo, L., Piccoli, M., and Testini, M.
Published: 2009

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