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Experimental studies devoted to the study of the mechanisms of the pathogenesis of acute peritonitis and the development of new methods of medical and surgical treatment are becoming increasingly relevant. Today, experimental medicine knows many different ways to modeling septic peritonitis and eliminate it, but the role of the local immune system is underestimated, whereas it takes a direct part in inflammation. The objective of our work to study morphological features of results of experimental modeling of septic peritonitis in white rats. The study included 15 sexually mature white male rats weighing 276.75±6.56 grams. A simulation of septic peritonitis was performed by perforating the upper part of the cecum with four punctures with a G16 injection needle. As a result of the experiment, after examination of the peritoneal cavity, all 15 animals were diagnosed with omentum tamponade of perforated damage to the caecum. In 11 cases, the perforated wall of the caecum was covered by the greater omentum (73.34 %), and in the other 4 animals, tamponade was performed by one of the epididymal omentum (26.66 %). The initial stage of tamponade with the greater or epididymal omentums of a perforated caecum begins on the first day of the experiment and consists of tight interstitial consolidation between them, as well as in the invasion of blood vessels from the omentum side to the focus of infection, which ensure the delivery of the appropriate immunocompetent cells. As a result of this process, intensive lymphoid infiltrates are formed in this area, as well as the growth of adipose tissue, which isolates the inflammatory focus from the peritoneal cavity with a thick layer. [ABSTRACT FROM AUTHOR]

Cisplatin (Cis) is an important chemotherapeutic agent used in cancer treatment. Males exposed to Cis were reported to exhibit testicular toxicity. Cis-induced testicular toxicity is mediated by oxidative stress, inflammation, testosterone inhibition and apoptosis. Accordingly, this study was conducted to evaluate the potential protective roles of infliximab (IFX), which is an anti-TNF-α agent, and of white tea (Camellia sinensis), which is known to possess antioxidant, anti-apoptotic, and anti-inflammatory effects, against Cis-induced testicular toxicity in rats. Rats were randomly assigned into five groups as follows: control group, Cisplatin (7 mg/kg) treatment group, Cisplatin (7 mg/kg) + infliximab (7 mg/kg) treatment group, cisplatin + white tea (WT) treatment group, and Cisplatin+ WT+IFX combined treatment group. In the present study, Cis exposure reduced the sperm count. It also increased testicular oxidative stress as well as the levels of inflammatory and apoptotic markers. Histopathological assays supported the biochemical findings. Treatment with IFX and/or WT restored testicular histology, preserved spermatogenesis, suppressed oxidative stress and apoptosis, and significantly ameliorated Cis-induced damage. It was concluded that white tea and infliximab could potentially serve as therapeutic options for the protection of testicular tissue against the harmful effects of Cis. [ABSTRACT FROM AUTHOR]

Copyright of Revista Cientifica de la Facultade de Veterinaria is the property of Universidad del Zulia, Facultad de Ciencias Veterinarias and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Scientia Medica is the property of EDIPUCRS - Editora Universitaria da PUCRS and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Tumores das células de Leydig são as neoplasias mais comuns do estroma gonadal. Eles representam 3% dos tumores testiculares, porém apenas 10% dos casos apresentam comportamento maligno. Os autores reportam 3 casos de tumores de células de Leydig do testículo observados no período de 6 anos. Todos os pacientes foram submetidos a orquiectomia radical por incisão inguinal. Os pacientes tiveram seguimento entre 5 meses e 5 anos; nenhum deles foi ao óbito pela doença ou mostrou sinais de recidiva tumoral.

Objetive: To determine the pre- and post-surgical clinical-ultrasound characteristics of children operated on for cryptorchidism. Material and methods: Descriptive and longitudinal study, data collected from medical records of the Hospital Sabogal, the variables were age at diagnosis, waiting time for orchidopexy, affected testicle, location of the testicle and testicular volume. Results: We included 34 children under 14 years with cryptorchidism, the age of diagnosis was 44 months and orchidopexy 49 months. The waiting time for orchidopexy was 4.72 months, the most affected testicle was the right (58.82%). 39 testicles were included, the primary canalith location (71.79 %), the final scrotal location (50.0%), the operative technique was inguinal (91.18%). The increase in testicular volume was 0.39 cm3, p = 0.0006, 95% CI (- 0.62, -0.17). Conclusions: The age of orchidopexy was 49 months and testicular volume increased by 0.39 cm3 after orchidopexy. [ABSTRACT FROM AUTHOR]

Oral exposure to synthetic and natural endocrine disruptors (ED) at different stages of life is related to alterations in the reproductive system. Ruminants represent a model for studying the effects of ED in humans due to some similarities in their development. Ruminants are considered of great importance due to continuous exposure to pasture and contaminated soils and human consumption of their meat. The present review aims to describe ED effects in ruminants’ reproduction, when they are consumed in the perinatal, postnatal-pre-adulthood, and adult stages. Feeding with phytoestrogens (PE) rich forage has no nocive consequences on the male reproductive system at any stages of life; in females, they produce more significant harmful effects when administered in adulthood. In the perinatal and postnatal-pre-adulthood stages, negative effects of synthetic ED were found in both males and females. This review presents study opportunities for further research related to oral exposure to ED. [ABSTRACT FROM AUTHOR]

La exposición oral a disruptores endocrinos (DE) sintéticos y naturales en las distintas etapas de la vida está relacionada con alteraciones en el sistema reproductivo. Los rumiantes representan modelos adecuados para estudiar el impacto de los DE en los humanos por algunas similitudes en su desarrollo, se consideran de gran importancia por la exposición continua a pastura y suelo contaminado, y por el consumo humano de su carne. El objetivo de la presente revisión es describir los efectos producidos por consumir DE en etapa perinatal, posnatal-preadultez y adultez en rumiantes. La alimentación con forraje rico en fitoestrógenos (FE), no tiene efectos nocivos sobre la reproducción de machos en ninguna etapa de la vida; en las hembras, producen mayores efectos nocivos cuando se administran en la adultez. En la etapa perinatal y posnatal-preadultez, se encontraron efectos negativos de los DE sintéticos, tanto en machos como en hembras. La presente revisión da a conocer las oportunidades de estudios para continuar con investigaciones relacionadas a la exposición oral a DE.

The concern of canine overpopulation is related to zoonoses such as rabies, which is responsible for 99% of human rabies cases, causing the death of approximately 59,000 people per year. Surgical sterilization is an effective, costly and invasive control method with limited impact. The effects of phytoestrogens on reproductive activity have been commonly studied in females and a limited number in males. Therefore, the objective of this study was to know the effect of subcutaneous administration of coumestrol on the gonadal activity of adult dogs as an alternative for their reproductive control. Basic seminal evaluation parameters, epididymal structure by ultrasonography, histological characteristics, as well as the presence of coumestrol by fluorescence and serum levels of testosterone and estrogens were determined. The administration of coumestrol for five weeks reduced sperm production, and evidenced changes in the echodensity and cellularity of the epididymis, associated with serum concentrations of estradiol and testosterone. Therefore, it is concluded that coumestrol administered subcutaneously has an estrogenic effect that can be used as a non-invasive method to help control fertility in adult dogs. [ABSTRACT FROM AUTHOR]

Copyright of Revista de Ciencias Médicas de Pinar del Río is the property of Editorial Ciencias Medicas and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

El eje hipotálamo-hipófiso-testicular es activo en la vida fetal y durante los primeros meses de la vida posnatal: la hipófisis secreta hormona luteinizante (LH) y folículo-estimulante (FSH), mientras que el testículo produce testosterona y factor insulino-símil 3 (INSL3) en las células de Leydig y hormona anti-Mülleriana (AMH) e inhibina B en las células de Sertoli. En la infancia, los niveles séricos de gonadotrofinas, testosterona y factor INSL3 disminuyen a valores prácticamente indetectables, pero los de AMH e inhibina B permanecen altos. En la pubertad, se reactivan las gonadotrofinas y la producción de testosterona e INSL3, aumenta la inhibina y disminuye la AMH, como signo de maduración de la célula de Sertoli. Sobre la base del conocimiento de la fisiología del desarrollo del eje, es posible utilizar clínicamente estos biomarcadores para interpretar la fisiopatología y diagnosticar las diferentes formas de hipogonadismo que pueden presentarse en la infancia y la adolescencia.

Presentado en sesión de 8 de julio de 1959

Presentado en sesión de 27 de marzo de 1957

Presentado en sesión de 6 de noviembre de 1957

Presentado en sesión de 7 de julio de 1954

Presentado en sesión de 3 de noviembre de 1954

Si bien la porción del genoma destinada a la síntesis de proteínas es muy pequeña, actualmente se sabe que casi todo el genoma se expresa bajo forma de ARNs no codificantes. Entre dichos ARNs se encuentran los ARNs no codificantes largos (lncRNAs). Aunque los lncRNAs han sido muy poco estudiados, recientemente han comenzado a centrar la atención de los investigadores, al descubrirse que los mismos pueden desempeñar diversas funciones en la regulación de la expresión génica. Además, su vinculación con patologías ha comenzado a ser puesta de manifiesto. Curiosamente, la cantidad de lncRNAs presentes en el testículo es abrumadoramente mayor que en cualquier otro órgano o tejido estudiado. Los perfiles de expresión de estos lncRNAs varían significativamente a lo largo de la espermatogénesis, y algunas evidencias sugieren que al menos algunos de ellos podrían participar en el proceso de formación de células germinales masculinas. No obstante, el conocimiento sobre el tema es aún muy escaso. En este trabajo revisamos la información disponible sobre la expresión de lncRNAs en el testículo y sus posibles funciones. Asimismo, analizamos algunos ejemplos que ilustran la participación de lncRNAs en el desarrollo de patologías como la infertilidad y el cáncer testicular.

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Copyright of Acta Veterinaria Brasilica is the property of Acta Veterinaria Brasilica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Among testicular traumas, blunt testicular trauma represents the majority of cases and usually affects men between 15 and 40 years of age. We present a finding of classic seminoma after an incidental trauma with subsequent surgical exploration and radical orchiectomy of the left testicle. The difficulty of research tools such as testicular ultrasound for physician support is highlighted. Seminomas are usually homogeneously hypoechoic masses. Magnetic resonance imaging can help confirm that a mass is intratesticular and provide data for local staging. Computed tomography provides valuable information for staging, including the presence and size of retroperitoneal lymph nodes. Management is limited. However, testicular seminoma is treated with radical inguinal orchiectomy and is highly curable even in advanced stages of the disease. Most physicians choose orchiectomy followed by surveillance for patients with stage I seminomatous disease and chemotherapy or radiation, followed by surgery for management of residual masses, for patients with stage II and higher disease. We stress the importance of clinical suspicion in these types of young patients and having an active search for these trivial traumas. [ABSTRACT FROM AUTHOR]

Acute affection of the scrotum or testicular torsion in pediatric is infrequency. The diagnosis and treatment should be as soon as possible with the intention to avoid an orchiectomy. We had a teenage patient with clinical evolution for more than 7 hours with testicular torsion and he under were for section of the sex gland. The pathology report was hemorrhagic necrosis. This case motivated to transmit our experience and reviewed some current references. [ABSTRACT FROM AUTHOR]

Currently, the sclerosing-type Sertoli cell tumor is classified as a variant of the NOS Sertoli cell tumors (without other specification), because it has been shown that both tumors present mutation in the CTNNB1 gene, which encodes the b-catenin (19), the relevance of its identification lies in the fact that this variant is correlated, although in a low percentage, with metastatic potential. A 56-year-old male, with a 7-year evolution, characterized by presenting left testicular pain with a slight increase in consistency in the lower pole of the left testicle, a testicular ultrasound was performed, which revealed a heterogeneous lesion of 2 cm in diameter maximum, dependent on the lower pole of the left testis; Left radical orchiectomy was performed, with histopathological report: testicular sertoli cell tumor. Later, with satisfactory evolution, with complete wound healing, and currently under surveillance, without the need for adjuvant treatment. Knowing their relative rarity and the few reported cases, testicular Sertoli cell tumors remain a relative mystery and today, they continue to be a challenge for diagnosis. With this case, we intend to support the knowledge and promote additional research on these tumors, with the aim of optimizing the diagnosis and providing adequate treatment. [ABSTRACT FROM AUTHOR]

O testículo é um órgão com função exócrina, relacionada com a produção, armazenamento e transporte de espermatozóides, e função endócrina relacionada com a produção de hormônios andrógenos como a testosterona. É subdividido em dois compartimentos – tubular e intertubular – compostos por tipos celulares que desempenham funções distintas. Dentre as células que compõem a gônada masculina, destacam-se as células germinativas, que originarão os espermatozóides; as células de Sertoli e as células de Leydig. O objetivo desta revisão é descrever as características estruturais dos testículos, dos tipos celulares que o compõe e as suas respectivas funções.

Si bien la porción del genoma destinada a la síntesis de proteínas es muy pequeña, actualmente se sabe que casi todo el genoma se expresa bajo forma de ARNs no codificantes. Entre dichos ARNs se encuentran los ARNs no codificantes largos (lncRNAs). Aunque los lncRNAs han sido muy poco estudiados, recientemente han comenzado a centrar la atención de los investigadores, al descubrirse que los mismos pueden desempeñar diversas funciones en la regulación de la expresión génica. Además, su vinculación con patologías ha comenzado a ser puesta de manifiesto. Curiosamente, la cantidad de lncRNAs presentes en el testículo es abrumadoramente mayor que en cualquier otro órgano o tejido estudiado. Los perfiles de expresión de estos lncRNAs varían significativamente a lo largo de la espermatogénesis, y algunas evidencias sugieren que al menos algunos de ellos podrían participar en el proceso de formación de células germinales masculinas. No obstante, el conocimiento sobre el tema es aún muy escaso. En este trabajo revisamos la información disponible sobre la expresión de lncRNAs en el testículo y sus posibles funciones. Asimismo, analizamos algunos ejemplos que ilustran la participación de lncRNAs en el desarrollo de patologías como la infertilidad y el cáncer testicular.

Copyright of Acta Veterinaria Brasilica is the property of Acta Veterinaria Brasilica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Compendium of Veterinary Sciences / Compendio de Ciencias Veterinarias is the property of Facultad de Ciencias Veterinarias de la Universidad Nacional de Asuncion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Diabetes is a metabolic disorder characterized by high blood sugar levels and it causes complications in many systems, including the reproductive system. As a result of diabetic conditions, one of the mechanisms that can cause repression of reproductive activity is testicular oxidant stress. The identification of diabetes on the cell signaling molecules axis is still under discussion. The aim of this study was to determine the effect of Transforming Growth Factor (TGFb), Nuclear Factor kappa B (NF-kB), Heat-schock 90b (HSP90b) signal pathways and E-cadherin cell adhesion molecule on infertility in diabetic rat testicular tissue. In our study, includes histological, molecular and biochemical analysis of testicular tissue removed at the end of the 2 weeks experiment period. A total of 14 adult male rats were divided as control and diabetes. No intervention was given to 7 male rats in the control group. For the diabetic group, 7 male rats were injected by intraperitoneal with a single dose of 55 mg/kg streptozotocin (STZ). TGFb, NF-kB, HSP90b and E-cadherin proteins were immunohistochemically studied to investigate possible tissue damage, inflammatory process, cell stabilization and integrity due to diabetes. In order to determine oxidant stress, lipid peroxidation product malondialdehyde (MDA), glutathione (GSH) and glutathione peroxidase (GPx) analyzes were performed. Fibrosis, inflammatory changes and loss of spermatogenetic series are prominent findings in the diabetic group. On analysis of all the samples with immunostaining, in the diabetic group, TGFb and NF-kB immunoexpression significantly increased, while Hsp90b and E-cadherin immunoexpression significantly decreased compared with control groups. Experimental diabetes was found to cause fibrosis, inflammation, disrupting cell adhesion and stabilization in testicular tissue. These results suggest that cellular therapy studies are needed for possible damage. [ABSTRACT FROM AUTHOR]

Bisphenol A (BPA) is an industrial chemical widely used to make polycarbonate plastics for packaging and epoxy resins. This study sought to examine how selenium (Se) affects BPA toxicity in terms of albino rats’ histological structure, antioxidant enzymes and reproductive organs (seminiferous tubules). Twenty-four adult male rats were divided into four experimental groups: Group 1: Control; Group 2: Orally administered BPA; Group 3: Orally administered sodium selenite; Group 4: Treated daily with BPA followed by selenium (Se). All experiment done for 4 weeks. BPA exposure caused changes in the testicular histological structure, which consists apoptosis, and led to changes in several biochemical markers: Malondialdehyde, catalase, superoxide dismutase, and glutathione peroxidase. However, these BPA side effects may be ameliorated in rats treated with BPA-plus-Se. These protective effects of Se may attributable to its ability to remove potentially damaging oxidizing agents in living organisms. The results may confirm that Se countered the oxidant effects and increased the BPA-induced stress response in rats. So, Se promotes the healthy growth and development of mammals by protecting them from oxidative stress. As human are greatly exposed to BPA and it can accumulate in tissues, there is concern about human reproductive functions particularly for occupational workers exposed usually to greater levels of BPA. Thus, the use of BPA in multiple industries must be restricted and the inaccurate usage of plastic containers should be avoided to decrease the health hazards. Administration of Se may protect against the adverse effects of BPA on reproductive functions and structures. [ABSTRACT FROM AUTHOR]

Objetivo: determinar la histopatología de los testículos de ratas BIOU: Wistar expuestas crónicamente a malatión en comparación con ratas no expuestas. Métodos: estudio experimental con 20 ratas machos asignadas al azar, 10 al grupo control y 10 al expuesto. La exposición consistió en la aplicación crónica de malatión de manera inhalada una vez a la semana durante 2 horas, por 14 semanas; las dosis empleadas fueron equivalentes a las usadas por humanos en agricultura. El grupo control fue expuesto a un placebo (agua destilada) al aire libre por el mismo lapso. Luego, fueron sacrificadas, se obtuvo una muestra sérica para la determinación de la acetilcolinesterasa y se les extrajeron los testículos para el estudio histopatológico. Resultados: los niveles de acetilcolinesterasa fueron significativamente más bajos (p = 0,0001) en el grupo expuesto que en el grupo control. En el estudio histopatológico con microscopia de luz, en el grupo expuesto se evidenció una vacuolización del epitelio germinal en el 50 % de los casos (p = 0,016) para un odds ratio (OR) de 3,00 (95 %: 1,46-6,13), así como espermatogénesis incompleta en el 40 % (p = 0,043) para un OR de 2,66 (95 %: 1,41-5,02); por su parte, no hubo alteraciones en el grupo control. Se observó una correlación inversa significativa (p = 0,0001) entre el número de alteraciones histopatológicas y la actividad de la acetilcolinesterasa. Conclusiones: estos resultados demuestran que la exposición crónica a malatión en ratas BIOU: Wistar puede producir efectos deletéreos en el sistema reproductivo de las ratas.

O sertolioma é um dos tumores que mais afetam cães idosos, sendo mais incidentes em animais criptorquidas. Geralmente esses tumores são extremamente expansivos, podendo comprimir e destruir os tecidos adjacentes. Para sua identificação é necessário à realização de exame histopatológico. Este trabalho teve por objetivo relatar a ocorrência de gonadopatia criptorquidica direita, acompanhada por processo neoplásico associado em um cão de 10 anos de idade. Após a orquiectomia os testículos foram encaminhados ao Laboratório de Patologia Animal da Universidade Federal Rural da Amazônia, e para a análise histopatológica o material foi processado rotineiramente para inclusão em parafina e colorações por hematoxilina-eosina (HE), e Tricrômico de Gomory. Histologicamente, observou-se espessamento albugíneo pela proliferação de tecido conjuntivo. No parênquima testicular os túbulos possuíam somente células de Sertoli, estavam diminuídos em número e espaçados por tecido conjuntivo denso proliferado. O processo neoplásico situava-se em uma região mais central e, morfologicamente, observou-se na configuração tubular, células demonstrando vacuolização citoplasmática e, alguns locais, dispondo-se em paliçadas, aspectos morfológicos característicos de sertolioma.

The aim of this study is to investigate the effects of Protocatechuic acid and Corchorus olitorius on streptozotocin (STZ) induced diabetic rat testis tissue. Randomly selected Wistar Albino rats were divided into five groups as; Diabetes Mellitus, Diabetes Mellitus treated with Corchorus Olitorus (STZ+CO), Diabetes Mellitus treated with Protacatechuic acid (STZ+PCA), Corchorus olitorius (CO), Protocatechuic acid (PCA) and Control. Diabetic model was generated by intraperitoneal injection of 60 mg/kg Streptozotosin. After 48 hours of the STZ injection, blood samples were collected from tail vein in order to measure blood glycose levels. Over 250 mg/dL accepted as diabetic subjets and fed with 250 mg/kg Corchorus olitorius or 20 mg/kg PCA by oral gavage for three weeks. At the end of the experiment, right testes were removed and fixed in 10 % neutral formaldehyde for paraffine embedding. Sections were stained by HE, Masson trichrome, PAS and TUNEL for microscopic evaluation. Control, PCA-only and Corchorus olitorius-only treated group testes tissues showed a normal tissue organization, when degeneration in seminiferous tubules, the vacuolization, seperations in spermatogenic cell series, outpouring of cell groups in the lumen, vesicular body formation, liquid accumulation in the interstitial region and edema were observed in STZ induced diabetic models and untreated groups. Besides, higher amount of TUNEL (+) stained cells were determined in STZ group. On the other hand, blood glucose level and number of TUNEL (+) stained cells were decreased as a result of PCA and Corchorus olitorius treatment. Because of the reduction of blood glucose level and apoptotic cell numbers, PCA and Corchorus olitorius decreace the complications of diabetes mellitus induced rat testis [ABSTRACT FROM AUTHOR]

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Introdução: o poliorquidismo é uma patologia incomum, contando cerca de 200 casos na literatura mundial. Relato de caso: relatamos um caso de poliorquidismo em um paciente do sexo masculino de 16 anos, diagnosticado por ultrassom e confirmado por ressonância magnética. Discussão: na maioria dos casos apresentados, há um testículo supranumérico, mas há relatos de mais de três, até cinco testículos, com gônadas supranuméricas em ambos os lados do escroto. O diagnóstico geralmente é feito no final da puberdade, aliás, com massa escrotal indolor ou no pronto-socorro, apresentando torção de todo o hemiscroto ou somente do testículo supranumerário, e o diagnóstico diferencial deve ser feito com cisto epididimário e espermatocele, além de outros massas extratesticulares (hidroceles, varicoceles, lipomas, tumores) e massas paratesticulares (hérnias, cálculos escrotais). Após a avaliação clínica inicial, o ultrassom é a primeira linha do exame subsidiário. A ressonância magnética é muito útil se o diagnóstico por ultrassom não for certo. Os testículos supranumerários têm as mesmas características de ressonância magnética que os testículos normais (intensidade do sinal intermediário nas imagens ponderadas em T1 e alta intensidade do sinal nas imagens ponderadas em T2). [ABSTRACT FROM AUTHOR]

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The tumor of the Sertoli cells is a common neoplasm in non-neutered male dogs of advanced age, generally showing benign behavior. The testicular growth the first signal for suspects of the affection and ultrasound can be used to locate and characterize it. However, histopathological analysis is necessary for the definitive diagnosis and orchiectomy is the most indicated treatment. This work aims to report a case of sertolioma in a 13-year-old domestic Shetland Shepherd dog treated at Hospital Veterinário Sylvio Barbosa Cardoso of the State University of Ceará in September 12th of 2019 with right testicular enlargement. A testicular clinical and ultrasound evaluation was performed, where an echogenic image of heterogeneous echotexture was seen in the right testicular parenchyma with evident internal vascularity After the performance of hematological and cardiac exams, the animal was forwarded to bilateral orchiectomy. The histopathological report concluded the presence of a neoplasm that reproduces Sertoli cells of the intratubular type. The animal received recommendations to be under observation, and to perform periodic exams mainly in association with its advanced age. The sertolioma presents a low metastatic potential, not being necessary the association with other treatments, nonetheless, requiring caution and attention of the veterinarian, once the confirmation of the cure is made necessary for the realization of periodic exams with the veterinarian monitoring. [ABSTRACT FROM AUTHOR]

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Copyright of Revista Brasileira de Reprodução Animal is the property of Revista Brasileira de Reproducao Animal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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The present work aimed to report a case of a Sertoli cell tumor associated with cryptorchidism in a Poodle dog of eight years old, that presented a mass in the inguinal region eight months ago. The previous history and evolution time were compatible with testicular feminization syndrome. It was observed a considerable increase in volume of the affected testis (left). The animal was submitted to an orchiectomy of the cryptorchidic testis and presented a good recovery. The histopathological examination revealed a diffuse sertolioma, and possibly the systemic manifestation of non-pruriginous bilateral symmetric alopecia was related to the presence of the tumor. [ABSTRACT FROM AUTHOR]

Abstract With the objective to assess the effect of scrotal bipartition on spermatogenesis in sheep, the testes were used from 12 crossbred rams of sheep farms in the municipality of Patos, Paraíba, Brazil, distributed into two groups: GI with six rams with scrotal bipartition, and GII with six rams without scrotal bipartition. The testicular biometry was measured and the testes were collected, fixed in Bouin and fragments were processed to obtain histological slides. The spermatogenesis yield and the Sertoli cell efficiency was estimated by counting the cells of the spermatogenetic line at stage one of the seminiferous epithelium cycle and the Sertoli cells. The results were submitted to analysis of variance with the ASSISTAT v.7.6 program and the mean values were compared by the Student-Newman-Keuls test (SNK) at 5% significance. The testicular biometric parameters did not show statistical difference (p>0.05) between the groups. The meiotic, spermatogenetic and Sertoli cell efficiency were higher in bipartitioned rams (p0.05) between GI and GII. The results indicated that there is superiority in the spermatogenetic parameters of bi-partitioned rams, suggesting that these sheep present, as reported in goats, indication of better reproductive indices.

Resumo: Foram utilizadas as gônadas e vias espermáticas de cinco animais machos, adultos em fase reprodutiva, da espécie Metachirus nudicaudatus Geoffroy 1803, única espécie do gênero, para descrever a morfologia do escroto, do testículo e das vias espermáticas. O Metachirus possui escroto pré-peniano e que contém os testículos permanentemente. A pele escrotal é não pigmentada e com poucos pelos e glândulas. A lâmina parietal da túnica vaginal apresenta-se pouco pigmentada. Os testículos são ovais e ligados ao epidídimo através do pedículo testículo-epididimário. Eles são envolvidos, externamente, pela cápsula testicular e sustentados por um estroma de natureza conjuntiva. As células intersticiais são os elementos predominantes no abundante tecido intertubular. Os túbulos seminíferos são largos, enovelados e envolvidos por uma túnica própria fibroelástica, contendo células mióides. O epitélio seminífero é formado pelas células espermatogênicas e de Sertoli intercaladas. Os túbulos seminíferos convergem em direção à extremidade capitata do testículo, ficando revestidos por apenas células de sustentação, caracterizando uma região de transição entre túbulos seminíferos e túbulos retos, ocupada por uma estrutura tipo "válvula" que obstrui parcialmente o lume tubular. Os túbulos retos reúnem-se para formar um único dúctulo eferente, que percorre uma pequena extensão intratesticular, atravessa a albugínea e penetra no pedículo testículo-epididimário. A parte flexuosa do dúctulo eferente forma um lóbulo separado na parte medial do corpo do epidídimo. O epidídimo é envolvido pela cápsula epididimária e constituído pelo ducto epididimário, que se encontra bastante enovelado. O ducto epididimário é revestido por epitélio simples colunar pseudoestratificado apresentando células principais, basais, apicais e de "halo claro". As células principais são predominantes e apresentam características morfológicas e histoquímicas que diferem ao longo do ducto, possibilitando a caracterização de nove diferentes zonas epididimárias. É no lume da zona sete (início da cauda) que começa o pareamento de espermatozoides. Esse fenômeno coincide com alterações morfológicas bem evidentes e uma maior quantidade de mucossubstâncias neutras é secretada nessa zona.O ducto deferente apresenta-se dividido em três partes: justa-epididimária, funicular e abdominal, baseando nas variações histológicas e histoquímicas de seu epitélio e componentes envolventes. O ducto deferente não apresenta ampola e nem cruza o ureter antes de desembocar na uretra. O funículo espermático contém o ducto deferente, artéria e veias testiculares, vasos linfáticos, nervos e um desenvolvido músculo cremáster. Seus componentes apresentam modificações estruturais nas regiões proximal, média e distal, sendo notável a peculiar rede admirável.

RESUMO: Objetivou-se avaliar a influência da estação do ano sobre a estrutura testicular de ovinos SRD. Foram utilizados 10 animais com idade entre dois e três anos. Os testículos foram seccionados e fixados em solução de Bouin por 24h. Os fragmentos foram submetidos ao processamento histológico, emblocados em parafina e corados com hematoxilina eosina. Foram avaliadas a proporção volumétrica dos compartimentos testiculares, o diâmetro dos túbulos seminíferos, altura do epitélio seminífero e frequências dos estágios do ciclo do epitélio seminíferos. Os dados foram submetidos à análise de variância a 5% de probabilidade, do programa estatístico SAS 9.0. Os resultados revelaram todos os valores pesquisados sofreram influência da estação do ano. O valor do diâmetro tubular foi de 143,98±17,83 e 170,37±26,64μm, a altura do epitélio seminífero foi de 44,92±9,23 e 50,06±13,61μm e a proporção volumétrica foi de 78,32±13,68 e 80,13±15,14% nos períodos seco e chuvoso, respectivamente. A quantificação das células germinativas e de Sertoli mostrou todos os valores foram maiores no período chuvoso quando comparados com o seco. Concluiu-se que a estação do ano interferiu na estrutura testicular, tendo em vista que todos os valores da proporção volumétrica dos componentes testiculares mostraram diferença significativa entre as estações do ano, pois os valores foram mais acentuados no período chuvoso.