472 results on '"Tertiary syphilis"'
Search Results
2. Tertiary syphilis and cardiovascular disease: the united triad: case report.
- Author
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Berhil, Taha, Radi, Fatima Zohra, Boussaadani, Badre El, and Raissouni, Zainab
- Abstract
Background Syphilis, owing to its natural course, can lead to long-term damage to the aortic valve, such as insufficiency and rarely stenosis, ostial coronary stenosis, and syphilitic aortitis. Cardiovascular involvement alongside neurological involvement dominates the prognosis. This should no longer be seen, thanks to awareness and prevention programmes, medical treatment, and antibiotics. Case summary We report a case of a 54-year-old chronic smoker with no previous history, admitted for respiratory distress amid an impaired general condition. An electrocardiogram was performed, which showed sinus rhythm with lateral ST depression and T -wave inversion. Coronary angiography revealed an ostial stenosis of the left coronary artery. Echocardiography displayed a globular dilated left ventricle with a left ventricular ejection fraction of 40% and severe aortic insufficiency (AI). Computed tomography angiography of the aorta showed a dilation of the thoracic aorta and suprarenal abdominal aorta. Syphilitic serology was positive. The patient underwent angioplasty, resulting in a satisfactory outcome, and subsequently received optimal treatment. Following a consultation with a cardiovascular surgeon and vascular team, it was decided to proceed with mechanical aortic valve replacement and aorto-coronary double bypass surgery, but vascular surgery of the ascending aortic aneurysm was not possible at once. Discussion Tertiary syphilis should always be considered when faced with isolated coronary ostial involvement, aortic aneurysm, and/or AI. What makes our case special is that the patient had almost all the cardiovascular complications of tertiary syphilis. Primary syphilis should always be prevented, diagnosed early, and treated appropriately with antibiotic therapy. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
3. Syphilitic ostial coronary artery occlusion treated with percutaneous coronary intervention: Case series and literature review
- Author
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Yasmine Baydoun, Yuriy Stukov, Matthew S. Purlee, Bailey Chagnon, Sergiy V. Salo, Andrii Y. Gavrylyshin, Vasyl Lazoryshynets, Olena Levchyshyna, Omar M. Sharaf, Giles J. Peek, Mark S. Bleiweis, and Jeffrey P. Jacobs
- Subjects
Acute coronary syndrome ,Coronary artery disease ,Percutaneous coronary intervention ,Tertiary syphilis ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Introduction: Non-atherosclerotic causes of acute coronary syndrome (ACS) are important contributors to a substantial number of acute ischemic coronary events. Syphilitic aortitis is a rare complication of tertiary cardiovascular syphilis that may result in ostial coronary artery stenosis, aortic insufficiency, and ascending aortic aneurysm. Methods: In this manuscript, we present two Case Reports of patients with bilateral syphilitic coronary artery ostial occlusion, and we review the associated literature. The immunofluorescent test was positive for syphilis in both patients. Results: Diagnostic coronary angiography revealed bilateral occlusions of the left main coronary artery (LMCA) and right coronary artery (RCA), which were successfully treated with percutaneous coronary intervention (PCI) with bare metal stents (BMS). After deployment of the stents, arterial blood flow was re-established with TIMI flow grade 3. Discussion: The angiographic finding of bilateral coronary ostial lesions in young patients should raise the suspicion of cardiovascular syphilis. Options for revascularization should be discussed amongst the patient and the Heart Team. PCI may be an option for treatment of isolated syphilitic coronary stenosis in the setting of acute hemodynamic instability or chronic inflammation.
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- 2023
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- View/download PDF
4. Liver and Gall Bladder
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Dawood, Gamal and Dawood, Gamal
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- 2022
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5. An Unusual Case of Tertiary Syphilis Behaving Like Tongue Squamous Cell Carcinoma.
- Author
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Solis, Roberto N, Kuhn, Brooks T, and Farwell, D Gregory
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Tongue ,Humans ,Syphilis ,Carcinoma ,Squamous Cell ,Tongue Neoplasms ,Tongue Diseases ,Granuloma ,Anti-Bacterial Agents ,Diagnosis ,Differential ,Biopsy ,Middle Aged ,Male ,granulomatous inflammation ,oral manifestations ,syphilis ,tertiary syphilis ,tongue ,Sexually Transmitted Infections ,Rare Diseases ,Dental/Oral and Craniofacial Disease ,Cancer ,Clinical Research ,Good Health and Well Being - Abstract
Syphilis may present with a myriad of oral manifestations in the primary, secondary, and tertiary stages, and may be confused with malignancy. Despite a rise in the incidence of syphilis, tertiary syphilis is exceedingly rare. Tertiary syphilis gummas usually affect the hard palate, while tongue involvement is very rare. A 55-year-old male with extensive smoking and alcohol use was referred for malignancy evaluation with an ulcerative mass creating a tongue cleft, and a positron emission tomography scan suggestive for malignancy. Biopsy results demonstrated no carcinoma but histology demonstrated granulomatous inflammation. Further laboratory results demonstrated elevated rapid plasma reagin titers with Treponema pallidum immunoglobulin G antibodies present. The patient was diagnosed with tertiary syphilis, received appropriate antibiotic therapy, and had healing of the tongue with a persistent cleft. Syphilis may mimic many disease processes. As such, it is important to include this disease in the differential of an unusual tongue lesion. An oral lesion may be the first sign of infection.
- Published
- 2018
6. [Translated article] AEDV Expert Consensus for the Management of Syphilis.
- Author
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Fuertes de Vega L, de la Torre García JM, Suarez Farfante JM, and Ceballos Rodríguez MC
- Abstract
Syphilis -the "great simulator" for classical venereologists-is re-emerging in Western countries despite adequate treatment; several contributing factors have been identified, including changes in sexual behaviour, which won't be the topic of this article though. In 2021, a total of 6613 new cases of syphilis were reported in Spain, representing an incidence of 13.9×100 000 inhabitants (90.5%, men). Rates have increased progressively since 2000. The clinical presentation of syphilis is heterogeneous. Although chancroid, syphilitic roseola and syphilitic nails are typical lesions, other forms of the disease can be present such as non-ulcerative primary lesions like Follmann balanitis, chancres in the oral cavity, patchy secondary lingual lesions, or enanthema on the palate and uvula, among many others. Regarding diagnosis, molecular assays such as PCR have been replacing dark-field microscopy in ulcerative lesions while automated treponemal tests (EIA, CLIA) are being used in serological tests, along with classical tests (such as RPR and HAART) for confirmation and follow-up purposes. The interpretation of these tests should be assessed in the epidemiological and clinical context of the patient. HIV serology and STI screening should be requested for anyone with syphilis. Follow-up of patients under treatment is important to ensure healing and detect reinfection. Serological response to treatment should be assessed with the same non-treponemal test (RPR/VDRL); 3-, 6-, 12-, and 24-month follow-up is a common practice in people living with HIV (PLHIV). Sexual contacts should be assessed and treated as appropriate. Screening is advised for pregnant women within the first trimester of pregnancy. Pregnant women with an abortion after week 20 should all be tested for syphilis. The treatment of choice for all forms of syphilis, including pregnant women and PLHIV, is penicillin. Macrolides are ill-advised because of potential resistance., (Copyright © 2024 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.)
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- 2024
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7. NODULO-ULCERATIVE SYPHILIS - CASE REPORT AND THE REVIEW OF LITERATURE.
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Skiepko, Urszula, Serwin, Agnieszka Beata, Piłasewicz-Puza, Agata, and Flisiak, Iwona
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SEXUALLY transmitted diseases ,SYPHILIS ,LITERATURE reviews ,SERODIAGNOSIS ,PENICILLIN G - Abstract
Copyright of Epidemiological Review / Przegląd Epidemiologiczny is the property of National Institute of Public Health - National Institute of Hygiene and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2022
- Full Text
- View/download PDF
8. Impending Aortic Rupture in a Patient with Syphilitic Aortitis
- Author
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Cocora M, Nechifor D, Lazar MA, and Mornos A
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tertiary syphilis ,giant aortic aneurysm ,aortic rupture ,bentall procedure ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Mioara Cocora,1 Dan Nechifor,1 Mihai-Andrei Lazar,2 Aniko Mornos2 1Department of Cardiovascular Surgery, Institute of Cardiovascular Diseases, Timisoara, Romania; 2Department of Cardiology, Institute of Cardiovascular Diseases, Timisoara, RomaniaCorrespondence: Mioara CocoraDepartment of Cardiovascular Surgery, Institute of Cardiovascular Diseases, Timisoara, RomaniaTel +40 722 824 703Fax +40 256 284 463Email mcocora@cardiologie.roAbstract: We report the case of a 48-year-old man, admitted for atrial fibrillation with rapid heart rate and intense chest pain. A quick evaluation revealed a giant aortic aneurysm with severe aortic regurgitation and pericardial fluid without a trace of aortic dissection. Because of high suspicion of aortic rupture, an emergency surgery was planned, and a Bentall procedure was performed. On examination of the aortic wall revealing vertical wrinkling with a tree bark aspect, suspicion of syphilitic aortitis arose. The diagnosis was confirmed through postoperative serologic testing and histological examination. Histopathologic differential diagnosis, special treatment and follow-up are presented.Keywords: tertiary syphilis, giant aortic aneurysm, aortic rupture, Bentall procedure
- Published
- 2021
9. Cerebral syphilitic gumma presenting with intracranial gumma and pathologic vertebrae fractures
- Author
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Ryan Thibodeau, MPH, Atin Goel, MBBS, Abtin Jafroodifar, MD, Matthew Klumpp, MD, Kavya Mirchia, MBBS, and Amar Swarnkar, MD
- Subjects
Neurosyphilis ,Treponema pallidum ,Tertiary syphilis ,Cerebral syphilitic gumma ,Syphilitic bone disease ,Central nervous system ,Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Abstract
A 37-year-old female was admitted with worsening neurologic function. On arrival from an outside hospital, the patient was obtunded and intubated. Magnetic resonance imaging of the brain revealed nodular enhancement of the leptomeninges, intracranial osteolytic lesions, and diffuse vasogenic edema causing mass effect. Imaging of the thoracic spine revealed pathologic compression fractures of 4 thoracic vertebrae. On review of the patient's electronic medical record, the patient had previously received treatment for secondary syphilis with intramuscular benzathine penicillin G. Surgical biopsies of the frontal bone and dura showed diffuse, chronic inflammation while a biopsy of the adjacent brain parenchyma revealed replicating spirochetes. The patient was subsequently prescribed dexamethasone and benzathine penicillin G. She regained neurologic function but later signed out against medical advice without completing her treatment regimen.
- Published
- 2021
- Full Text
- View/download PDF
10. Contained rupture of an aortic arch aneurysm in a patient with syphilitic aortitis. A case report
- Author
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Victor Bilman, Luca Bertoglio, Germano Melissano, and Roberto Chiesa
- Subjects
tertiary syphilis ,aortic aneurysm ,aortic rupture ,endovascular technique ,Surgery ,RD1-811 ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Syphilitic aortitis is a rare complication of tertiary syphilis, which can lead to aortic aneurysm formation, aortic valvular insufficiency, and ostial coronary stenosis. Syphilis has re-emerged worldwide over recent decades and vascular surgeons should be aware of its cardiovascular manifestations. Atypical clinical presentation, such as hemoptysis and a computed tomography angiography pattern of a thicker aneurysmal wall with ulcer-like aneurysm projections, should raise suspicion of syphilitic aortic aneurysm. An early diagnosis and appropriate surgical and medical therapies significantly contribute to successful treatment and favorable prognosis. Herein is reported the case of an 82-year-old male patient, positive for syphilis infection, with impending aortic arch aneurysm rupture treated with a hybrid arch repair. After 7 months, the patient was brought to the emergency room in cardiac arrest. Unsuccessful cardiopulmonary resuscitation maneuvers were performed, and an autopsy showed cardiac tamponade due to rupture of the ascending aorta.
- Published
- 2022
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- View/download PDF
11. A peculiar case of syphilis infection: The great imitator is on the rise
- Author
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MJP Eijmael, RG de Bruin, V. Hira, and T. Koster
- Subjects
Uveitis ,Ocular syphilis ,Tertiary syphilis ,Infectious and parasitic diseases ,RC109-216 - Abstract
The incidence of syphilis is on the rise worldwide and can pose many diagnostic and therapeutic difficulties for doctors. Given the wide variety of presenting symptoms, syphilis is also known as the great imitator, which in turn frequently leads to a pronounced diagnostic- and therapeutic delay for patients. Here we present a case report of syphilitic uveitis and papillitis accompanied by acute vision loss, a rare presentation of a tertiary syphilis infection that clinically mimicked a giant cell arteritis (GCA) or arteritic anterior ischemic optic neuropathy (AAION). The patient was treated with high-dose intravenous benzyl penicillin after which full vision was restored. By presenting this case, we hope to raise awareness for the increasing incidence of syphilis infections and stress the importance of syphilis testing in patients with otherwise unexplained uveitis.
- Published
- 2022
- Full Text
- View/download PDF
12. Aortitis sifilítica: manifestación olvidada de la sífilis
- Author
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Laura María Uribe-Arango, Mateo Mejía-Zuluaga, Tatiana María Bedoya-Jaramillo, Alejandro Arroyave-Carvajal, and Mauricio Duque-Ramírez
- Subjects
Tertiary syphilis ,Cardiovascular syphilis ,Syphilitic aortitis ,Aortic valve failure ,Aortic aneurysm ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Resumen: La sífilis es una infección bacteriana producida por el Treponema pallidum (espiroqueta). Consta de varias etapas: primaria, secundaria y terciaria, según el tiempo de evolución desde el momento en que se adquiere la infección. Cada etapa comprende diferentes manifestaciones clínicas; los síntomas cardiovasculares forman parte de la sífilis terciaria, en cuyo caso la aortitis sifilítica es la principal forma de presentación.Se expone el caso de un paciente que consultó por déficit neurológico focal, en quien por medio de estudios de extensión se documentó neurosífilis e insuficiencia valvular aórtica severa secundaria a perforación de la válvula coronaria derecha, que requirió recambio valvular aórtico por bioprótesis. Adicionalmente, se hace una revisión de las principales manifestaciones cardiovasculares de esta enfermedad.Aunque en la era postantibiótica este tipo de manifestaciones tardías son cada vez menos frecuentes, es imperativo conocerlas. Abstract: Syphilis is a bacterial infection caused by Treponema pallidum (spirochete). It has various stages: primary, secondary and tertiary; depending on the time to progression from the moment the infection is acquired. Each stage involves various clinical manifestations; cardiovascular symptoms are part of tertiary syphilis, and syphilitic aortitis is the main form of presentation.We present the case of a patient who consulted with a focal neurological deficit, in whom extension studies reported neurosyphilis and severe aortic failure secondary to perforation of the right coronary valve, which required aortic valve replacement by bioprosthesis. We also undertake a review of the main cardiovascular manifestations of this disease.Although in the post-antibiotic era this type of late manifestation is increasingly less frequent, it is imperative that we are aware of it.
- Published
- 2020
- Full Text
- View/download PDF
13. AEDV Expert Consensus for the Management of Syphilis.
- Author
-
Fuertes de Vega L, de la Torre García JM, Suarez Farfante JM, and Ceballos Rodríguez MC
- Abstract
Syphilis -the "great simulator" for classical venereologists-is re-emerging in Western countries despite adequate treatment; several contributing factors have been identified, including changes in sexual behaviour, which won't be the topic of this article though. In 2021, a total of 6613 new cases of syphilis were reported in Spain, representing an incidence of 13.9×100 000 inhabitants (90.5%, men). Rates have increased progressively since 2000. The clinical presentation of syphilis is heterogeneous. Although chancroid, syphilitic roseola and syphilitic nails are typical lesions, other forms of the disease can be present such as non-ulcerative primary lesions like Follmann balanitis, chancres in the oral cavity, patchy secondary lingual lesions, or enanthema on the palate and uvula, among many others. Regarding diagnosis, molecular assays such as PCR have been replacing dark-field microscopy in ulcerative lesions while automated treponemal tests (EIA, CLIA) are being used in serological tests, along with classical tests (such as RPR and HAART) for confirmation and follow-up purposes. The interpretation of these tests should be assessed in the epidemiological and clinical context of the patient. HIV serology and STI screening should be requested for anyone with syphilis. Follow-up of patients under treatment is important to ensure healing and detect reinfection. Serological response to treatment should be assessed with the same non-treponemal test (RPR/VDRL); 3-, 6-, 12-, and 24-month follow-up is a common practice in people living with HIV (PLHIV). Sexual contacts should be assessed and treated as appropriate. Screening is advised for pregnant women within the first trimester of pregnancy. Pregnant women with an abortion after week 20 should all be tested for syphilis. The treatment of choice for all forms of syphilis, including pregnant women and PLHIV, is penicillin. Macrolides are ill-advised because of potential resistance., (Copyright © 2024 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF
14. Syphilis
- Author
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Hartrich, Molly, Taira, Taku, and Rose, Emily, editor
- Published
- 2018
- Full Text
- View/download PDF
15. Non-itchy, Nodular Intermittently Healing Persistent Lesions on the Neck, Arms and Gluteus: A Quiz
- Author
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Teodora Pumnea, Zeno Fiocco, Benjamin M. Clanner-Engelshofen, Michael Flaig, Lars E. French, and Markus Reinholz
- Subjects
tertiary syphilis ,treponema pallidum ,infectious diseases ,late stage infection ,gummatous syphilis ,Dermatology ,RL1-803 - Published
- 2021
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- View/download PDF
16. Tertiary syphilis mimicking metastatic rectal cancer.
- Author
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Smith, Matthew J, Ong, Meydene, and Maqbool, Abrar
- Subjects
- *
RECTAL cancer , *SYPHILIS , *SEXUALLY transmitted diseases , *METASTASIS , *LIVER metastasis , *TREPONEMA pallidum - Abstract
Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. Tertiary syphilis, a late-stage multi-visceral complication of the disease is characterized by its diversity of clinical manifestations. Here, we present the first documented case of tertiary syphilis that clinically and radiologically mimicked primary rectal cancer with hepatic metastasis. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
17. Syphilitic Popliteal Pseudoaneurysm Complicated by Acute Lower-Limb Ischemia.
- Author
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Arasu, Rohan, Baimatova, Irina, and Cohen, Toby
- Subjects
- *
DIAGNOSIS of syphilis , *ISCHEMIA , *SAPHENOUS vein , *LEG , *VASCULAR surgery , *PENICILLIN , *FALSE aneurysms , *THROMBOEMBOLISM , *POPLITEAL artery , *ANGIOPLASTY , *DISEASE complications - Abstract
Case presentation: We present a case of a patient with a syphilitic popliteal pseudoaneurysm who developed acute lower-limb ischemia secondary to thromboembolism related to the pseudoaneurysm. The diagnosis of a syphilitic popliteal aneurysm was made due to positive syphilitic serological testing and with exclusion of all other potential causes. The pseudoaneurysm was surgically repaired using a great saphenous vein patch angioplasty, which was done without delay to prevent further thromboembolic complications. This was then followed by a course of intravenous benzyl penicillin. Discussion: Peripheral arterial involvement of tertiary syphilis remains exceedingly rare, with the vast majority of reported cases of vascular syphilis relating to aortic involvement. Given the paucity of literature on this condition, there is no good evidence to guide current management. Conclusion: With the globally increasing rates of syphilis, more cases of peripheral arterial involvement may become apparent, as was the case in the early 20th century. [ABSTRACT FROM AUTHOR]
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- 2022
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18. The Great Masquerader: Recurrent Ischemic Strokes Secondary to Meningovascular Syphilis in a Man With Cardiovascular Stroke Risk Factors.
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Carranza O, Waheed S, and Yousuf F
- Abstract
A male in his 60s with stroke risk factors presented with confusion and word-finding difficulties. He was diagnosed with acute ischemic stroke in the right basal ganglia. He was started on secondary stroke prevention measures including dual antiplatelet therapy and a high-dose statin. A highly reactive rapid plasma reagin (RPR) was performed as part of the workup and found to be positive. Follow-up fluorescent treponemal antibody absorption (TPA) test was also positive, confirming a diagnosis of syphilis. He was discharged home with a scheduled course of antibiotic treatment for tertiary syphilis but returned due to a new episode of transient facial paralysis. Further workup and physical exam findings revealed the patient had neurosyphilis. He was started on the appropriate antibiotic therapy, which significantly improved his confusion and prevented new episodes of stroke., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2024, Carranza et al.)
- Published
- 2024
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19. Surgery for Ascending Aortic Aneurysm and Aortic Valve Insufficiency in Conditions of Active Proceeding Syphilitic Aortitis and Valvulitis.
- Author
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Malyshev M, Safuanov A, Malyshev A, Rostovykh A, Sinyukov D, Rostovykh N, and Trushina V
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- Humans, Treatment Outcome, Anti-Bacterial Agents therapeutic use, Aortic Valve diagnostic imaging, Aortic Valve surgery, Syphilis, Cardiovascular diagnosis, Syphilis, Cardiovascular diagnostic imaging, Aortic Valve Insufficiency diagnostic imaging, Aortic Valve Insufficiency etiology, Aortic Valve Insufficiency surgery, Aneurysm, Ascending Aorta, Aortic Aneurysm diagnostic imaging, Aortic Aneurysm etiology, Aortic Aneurysm surgery
- Abstract
A syphilitic aortitis is a late cardiovascular lesion of tertiary syphilis that has become exceptionally rare in the antibiotic era but not eradicated completely. Syphilitic aortitis of ascending aorta complicates in ascending aortic aneurysm formation and aortic valve regurgitation, both requiring surgical treatment. After surgery, lifelong surveillance of the remainder of the aorta is recommended because of a priori supposed high incidence of delayed involvement of noninvolved aortic segments. A 3-year follow-up result of surgery of syphilitic ascending aortic aneurysm with aortic valve regurgitation in condition of active ongoing syphilitic aortitis and valvulitis is described with addressing the dimensions of remaining aortic segments. This case demonstrates that the dilatation of the remainder of the aorta does not occur during 3 years, at least when anti-syphilitic course of antibiotic is used just after operation without additional treatment during the follow-up period. A few reports on surgical treatment of syphilitic aneurysms of the ascending aorta are discussed.
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- 2024
- Full Text
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20. A rare case of tertiary syphilis spondylodiscitis of the upper cervical spine: Diagnostic and therapeutic complexity, review of literature
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Valerio Cipolloni, Luigi Aurelio Nasto, Luca Piccone, Domenico Alessandro Santagada, Virginia Sangiorgi, Roberto Pola, Antonello Leone, and Enrico Pola
- Subjects
Tertiary syphilis ,Treponema pallidum ,Osteolytic spinal lesion ,VDRL test ,Benzylpenicillin. ,Orthopedic surgery ,RD701-811 - Abstract
Syphilis is a sexually transmitted disease caused by the spirochetes Treponema pallidum. Syphilitic spinal lesions present as erosive bone lesions often simulating spondylodiscitis or cancer. In this article we describe a rare case of cervical osteolytic lesion from tertiary syphilis. A 45-year-old male with axial neck pain, without fever presented with an isolated osteolytic lesion at C3. Tuberculous spondylitis was initially suspected. A new CT and contrast enhanced MRI of the cervical spine and of the neck showed an extention of the bone lesion at C3 with bilateral lymphadenomegaly. To confirm the diagnosis of tertiary syphilis, US-guided biopsy of the lymph nodes was performed. The patient was treated with i.m. benzylpenicillin 2.4 MIU and the follow-up showed clinical and radiological resolution of the condition. The aim of this case report is to raise awareness of tertiary syphilis in the differential diagnosis of lytic lesions of the spine among the spinal community.
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- 2020
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21. DEMENCIA RÁPIDAMENTE PROGRESIVA POR NEUROSÍFILIS (PARÁLISIS GENERAL). UN CASO TRATABLE DE DEMENCIA.
- Author
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PABLO PAVIOLO, JUAN, CELESTE IMBACH, MARÍA, NOCENTI, ZULMA A., and DURAND, BRUNO L.
- Abstract
Copyright of Medicina (Buenos Aires) is the property of Medicina (Buenos Aires) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2020
22. Hysterical Hypnosis and Infectious Theatre
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Marshall, Jonathan W. and Marshall, Jonathan W.
- Published
- 2016
- Full Text
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23. Contemporary Theories
- Author
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Uszkalo, Kirsten C. and Uszkalo, Kirsten C.
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- 2015
- Full Text
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24. Syphilitic coronary artery ostial stenosis resulting in acute myocardial infarction
- Author
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Rūta Žvirblytė, Eglė Ereminienė, Aistė Montvilaitė, Antanas Jankauskas, and Vytenis Ivanauskas
- Subjects
Syphilitic aortitis ,Tertiary syphilis ,Acute myocardial infarction ,Coronary ostial stenosis ,Medicine (General) ,R5-920 - Abstract
Cardiovascular abnormalities are well-known manifestations of a late form of syphilis – tertiary syphilis. Since the era of antibiotics, the incidence of late manifestations of syphilis has declined almost to a rare entity. The injury of aorta (the aortitis with a dilatation of aortic root and its associated complications) is the most common between all the cardiovascular lesions. A less common manifestation of syphilitic aortitis is coronary artery ostial narrowing related to aortic wall thickening. We present the case of a 37-year-old male who was treated for an acute myocardial infarction due to bilateral coronary artery ostial stenosis secondary to syphilitic aortitis. According to the multidisciplinary decision, surgical revascularization (coronary artery bypass grafting, CABG) was performed. According to dermatologist recommendation, patient postoperative cardiovascular treatment was supplemented with intramuscular doses of benzathine penicillin recommended for tertiary syphilis. Further follow-up visits were also planned to detect possible changes of the aortic wall, dynamics of aortic regurgitation or potential anastomotic restenosis due to progression of aortitis.
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- 2017
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25. A dissecting aneurysm of the sinus of Valsalva involving the inter‐ventricsular septum in a patient with syphilis and a quadricuspid aortic valve.
- Author
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Li, Xiang, Zhong, Yue, Rao, Li, and Bai, Wenjuan
- Subjects
- *
ECHOCARDIOGRAPHY , *SYPHILIS , *HEART septum , *CONGENITAL heart disease , *SINUS of valsalva , *AORTIC dissection , *AORTIC valve diseases - Abstract
Aneurysms of the sinus of Valsalva are rare, with dissecting aneurysms of the sinus of Valsalva that extend into the inter‐ventricular septum being even more rare. This report describes a young patient with syphilis and a quadricuspid aortic valve who experienced a spontaneously dissecting aneurysm of the sinus of Valsalva and the basal inter‐ventricular septum. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
26. Syphilitic ostial coronary artery occlusion treated with percutaneous coronary intervention: Case series and literature review.
- Author
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Baydoun Y, Stukov Y, Purlee MS, Chagnon B, Salo SV, Gavrylyshin AY, Lazoryshynets V, Levchyshyna O, Sharaf OM, Peek GJ, Bleiweis MS, and Jacobs JP
- Abstract
Introduction: Non-atherosclerotic causes of acute coronary syndrome (ACS) are important contributors to a substantial number of acute ischemic coronary events. Syphilitic aortitis is a rare complication of tertiary cardiovascular syphilis that may result in ostial coronary artery stenosis, aortic insufficiency, and ascending aortic aneurysm., Methods: In this manuscript, we present two Case Reports of patients with bilateral syphilitic coronary artery ostial occlusion, and we review the associated literature. The immunofluorescent test was positive for syphilis in both patients., Results: Diagnostic coronary angiography revealed bilateral occlusions of the left main coronary artery (LMCA) and right coronary artery (RCA), which were successfully treated with percutaneous coronary intervention (PCI) with bare metal stents (BMS). After deployment of the stents, arterial blood flow was re-established with TIMI flow grade 3., Discussion: The angiographic finding of bilateral coronary ostial lesions in young patients should raise the suspicion of cardiovascular syphilis. Options for revascularization should be discussed amongst the patient and the Heart Team. PCI may be an option for treatment of isolated syphilitic coronary stenosis in the setting of acute hemodynamic instability or chronic inflammation., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2023 The Authors.)
- Published
- 2023
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27. The Making of the Patient Population
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Hide, Louise and Hide, Louise
- Published
- 2014
- Full Text
- View/download PDF
28. Aortic aneurysm in a patient with syphilis-related spinal pain and paraplegia
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Daniel Brito de Araujo, Danise Senna Oliveira, Rodrigo Kraft Rovere, and Umberto Lopes de Oliveira Filho
- Subjects
back pain ,tertiary syphilis ,syphilitic aneurysm ,Medicine - Abstract
The tertiary stage of syphilis is nowadays extremely rare, showing predilection for the cardiovascular and nervous systems. A 57-year-old Caucasian man sought medical assistance due to back pain that evolved to paraplegia of the lower limbs. A thoracic CT scan demonstrated an important aneurysmatic lesion of the descending thoracic aorta causing erosion of the vertebral bodies and VDRL and FTA-abs positivity. Although rare, syphilitic aortitis, the hallmark of cardiovascular syphilis, should be considered in the differential diagnosis in patients with thoracic aneurysm when in the absence of classic risk factors for atherosclerosis, especially in cases that progress with erosion of vertebral bodies.
- Published
- 2017
- Full Text
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29. Syphilis—An Elusive Diagnosis
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Karmen Hopkins and Donna L. Gullette
- Subjects
Advanced and Specialized Nursing ,Pediatrics ,medicine.medical_specialty ,business.industry ,Primary Syphilis ,Tertiary Syphilis ,medicine.disease ,Rash ,Asymptomatic ,Serology ,medicine ,Syphilis ,medicine.symptom ,Latent Syphilis ,business ,Chancre - Abstract
Increases in the prevalence of syphilis, along with difficulties in recognizing its various clinical presentations, make it an elusive diagnosis. A primary asymptomatic chancre may go unnoticed. Secondary syphilis rash can masquerade as numerous dermatological conditions. Latent syphilis is asymptomatic. Tertiary syphilis can affect the cardiovascular and neurological systems. Failure to correctly diagnose syphilis in its earlier stages leads to dissemination of infection to sexual partners. A positive screening nontreponemal test is confirmed with a treponemal test. Treatment response is monitored by serologic titers. Sexual contacts must be treated. Diagnosis, treatment, and management are presented for 4 stages of syphilis.
- Published
- 2021
30. Mercury poisoning in two patients with tertiary syphilis from the Ca’ Granda hospital (17th‐century Milan)
- Author
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Mirko Mattia, Carmelo Messina, Antonia Francesca Franchini, P.M. Galimberti, Luca Maria Sconfienza, Lucie Biehler-Gomez, Gaia Giordano, Cristina Cattaneo, Domenico Di Candia, Carlotta Sala, Fabrizio Slavazzi, and Alessandro Porro
- Subjects
Archeology ,History ,Pediatrics ,medicine.medical_specialty ,business.industry ,medicine ,medicine.disease ,Tertiary Syphilis ,business ,Mercury poisoning - Published
- 2021
31. Sudden death due to rupture of an aortic syphilitic aneurysm
- Author
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Mohit Chauhan, Konstatin N. Krupin, Roger W. Byard, Maksim A. Kislov, and Olga L. Romanova
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medicine.medical_specialty ,business.industry ,General Medicine ,Ruptured Aortic Aneurysm ,Syphilitic aortitis ,medicine.disease ,Tertiary Syphilis ,Hemopericardium ,Sudden death ,Pathology and Forensic Medicine ,Surgery ,Aortic aneurysm ,Cardiac tamponade ,cardiovascular system ,Medicine ,Syphilis ,business - Abstract
A 26-year-old man who suddenly collapsed and died was found at autopsy to have a ruptured aortic aneurysm which had the classic "tree bark" appearance of tertiary syphilis. Tracking of blood into the pericardial sac had resulted in sudden death from cardiac tamponade. Serological results were consistent with syphilis and HIV was excluded. Sudden death in a young HIV-negative man from the effects of syphilis is exceedingly rare nowadays.
- Published
- 2021
32. Challenges in the Diagnosis of Tertiary Syphilis: Case Report with Literature Review
- Author
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Lucyna Jankowska, Zygmunt Adamski, Adriana Polańska, Monika Bowszyc-Dmochowska, Katarzyna Plagens-Rotman, Piotr Merks, Magdalena Czarnecka-Operacz, and Ryszard Żaba
- Subjects
Health, Toxicology and Mutagenesis ,Public Health, Environmental and Occupational Health ,tertiary syphilis ,diagnosis ,treatment ,Humans ,Female ,Syphilis ,Skin - Abstract
Tertiary syphilis is a large diagnostic challenge. It is rarely the case that it affects the skin, bone tissue and the eyes at the same time. The presented case shows that extensive symptomatology of syphilis poses a challenge in making a proper diagnosis in patients whose history does not suspect STDs. The study aims to present the case of a young woman hospitalized with a suspected autoimmune disease, diagnosed with symptomatic late syphilis with involvement of the skin, bones and eyes.
- Published
- 2022
33. Conclusion: The Twilight of an Idol
- Author
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Joullié, Jean-Etienne and Joullié, Jean-Etienne
- Published
- 2013
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34. Misfits in France : Wild(e) about Dieppe
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Barnes, Julian, Lee, Hermione, Radford, Andrew, editor, and Reid, Victoria, editor
- Published
- 2012
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35. A rare case of tertiary syphilis spondylodiscitis of the upper cervical spine: Diagnostic and therapeutic complexity, review of literature.
- Author
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Cipolloni, Valerio, Nasto, Luigi Aurelio, Piccone, Luca, Santagada, Domenico Alessandro, Sangiorgi, Virginia, Pola, Roberto, Leone, Antonello, and Enrico, Pola
- Subjects
- *
SPONDYLODISCITIS , *CERVICAL vertebrae , *SYPHILIS , *SEXUALLY transmitted diseases , *LITERATURE reviews , *TREPONEMA pallidum - Abstract
Syphilis is a sexually transmitted disease caused by the spirochetes Treponema pallidum. Syphilitic spinal lesions present as erosive bone lesions often simulating spondylodiscitis or cancer. In this article we describe a rare case of cervical osteolytic lesion from tertiary syphilis. A 45-year-old male with axial neck pain, without fever presented with an isolated osteolytic lesion at C3. Tuberculous spondylitis was initially suspected. A new CT and contrast enhanced MRI of the cervical spine and of the neck showed an extention of the bone lesion at C3 with bilateral lymphadenomegaly. To confirm the diagnosis of tertiary syphilis, US-guided biopsy of the lymph nodes was performed. The patient was treated with i.m. benzylpenicillin 2.4 MIU and the follow-up showed clinical and radiological resolution of the condition. The aim of this case report is to raise awareness of tertiary syphilis in the differential diagnosis of lytic lesions of the spine among the spinal community. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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36. A Narrative Review of the Many Psychiatric Manifestations of Neurosyphilis: The Great Imitator.
- Author
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Kaur B and Khanna D
- Abstract
Neurosyphilis is an infection of the central nervous system caused by the spirochete, Treponema pallidum . New syphilis infections have been increasing around the world each year. This disease was much of a concern in the pre-penicillin era, where when left untreated many cases progressed to tertiary syphilis which can commonly manifest as neurosyphilis. Of particular interest, neurosyphilis has been linked to masquerading itself as various psychiatric conditions. This narrative review focuses on exploring psychiatric manifestations of neurosyphilis as well as the importance of screening in psychiatric settings and clinicians maintaining high clinical suspicion of the disease. A systematic search was conducted for published articles from 2003 to 2023 using PubMed, EMBASE, and Google Scholar. A total of 66 articles met the criteria and were used for detailed analysis, where psychiatric manifestations and clinical progression of patients were discussed in detail. Psychiatric manifestations that were explored include dementia, delirium, depression, mania, personality changes, and psychosis. One of the most common manifestations of neurosyphilis appears to be severe neurocognitive impairment. There are also rare psychiatric conditions neurosyphilis mimics that have been described in literature such as Capgras syndrome and Geschwind syndrome. A narrative review of the literature revealed a low level of clinical awareness of neurosyphilis as a possible etiology of various psychiatric disorders. This resulted in delayed or inaccurate diagnosis and consequently delayed initiation of adequate treatment. Considering that many psychiatric manifestations of neurosyphilis are reversible with proper treatment, it is imperative to implement routine screening for syphilis among psychiatric patients., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2023, Kaur et al.)
- Published
- 2023
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37. Voltaire’s Skeptical Jurisprudence: Contra Leibnizian Optimism in Candide
- Author
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Riley, Patrick, Pattaro, Enrico, editor, Canale, Damiano, editor, Grossi, Paolo, editor, Hofmann, Hasso, editor, and Riley, Patrick, editor
- Published
- 2009
- Full Text
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38. African Americans and HIV Clinical Research
- Author
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Smith, Kimberly, King, William D., Stone, Valerie, editor, Ojikutu, Bisola, editor, Rawlings, M. Keith, editor, and Smith, Kimberly Y., editor
- Published
- 2009
- Full Text
- View/download PDF
39. Spinal Syphilitic Gumma: A Rare Presentation of an Old Disease
- Author
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Dominic Worku, Laura Byrne, Catherine Cosgrove, and Angela Houston
- Subjects
medicine.medical_specialty ,Tuberculosis ,Neurology ,medicine.diagnostic_test ,business.industry ,Case Report ,Context (language use) ,Neurological examination ,Infectious and parasitic diseases ,RC109-216 ,General Medicine ,medicine.disease ,Tertiary Syphilis ,Dermatology ,Neurosyphilis ,03 medical and health sciences ,0302 clinical medicine ,Gumma ,medicine ,Syphilis ,030212 general & internal medicine ,business ,030217 neurology & neurosurgery - Abstract
Syphilis is an ancient condition which still is of global concern today. Despite better awareness amongst clinicians and improving diagnostics, it remains likely underdiagnosed in part because of its namesake the ‘great imitator.’ While many patients suffer primary or secondary disease, tertiary syphilis characterised by gumma is rare, especially in the context of neurosyphilis. Here, we report a rare case of a well-controlled human immunodeficiency virus- (HIV-) positive gentleman with a history of previous syphilis and epilepsy who presented with progressive left leg weakness leading to immobility and altered bowels and, on neurological examination, Brown-Sequard syndrome. Magnetic resonance imaging (MRI) of the spine revealed two peripherally enhancing cavitating lesions at T4-T5 with associated meningeal thickening and cord oedema. Cerebrospinal fluid (CSF) analysis revealed high protein (3.07 g/dL) and white cell count (7 × 109/L) with negative cryptococcal antigen, tuberculosis molecular testing (GeneXpert), microscopy and culture, and viral polymerase chain reaction (PCR). CSF serology was positive for Treponema pallidum particle agglutination (TPPA) 10240 and RPR 1 in 2 suggesting active disease. While TB treatment had been started prior to these investigations on day 11, 14-day high-dose benzylpenicillin therapy commenced. Repeat MRI of the spine at days 12 and 22 showed incremental improvements in all parameters which correlated with improving functionality and neurology. According to our literature search, this represents the 13th case recorded for spinal syphilitic gumma and the only case recorded in a HIV-positive individual and adds to the evidence that, in the absence of rapidly changing neurology, medical management can lead to good clinical outcomes.
- Published
- 2021
40. Syphilitic Aortitis and Coronary Ostial Stenosis: A Focused Review
- Author
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David John Polman, Michael Freilich, and Isabel M. McFarlane
- Subjects
medicine.medical_specialty ,business.industry ,General surgery ,Cardiovascular syphilis ,030204 cardiovascular system & hematology ,Syphilitic aortitis ,medicine.disease ,Tertiary Syphilis ,Review article ,03 medical and health sciences ,Coronary ostial stenosis ,0302 clinical medicine ,Epidemiology ,medicine ,General Earth and Planetary Sciences ,030211 gastroenterology & hepatology ,In patient ,business ,Complication ,General Environmental Science - Abstract
Cardiovascular syphilis is a manifestation of tertiary syphilis, and is one that can have many complications, including syphilitic aortitis. In this review article, we review the epidemiology and pathophysiology of syphilitic aortitis and focus in on one of its complication, coronary ostial stenosis. Next, we will discuss the diagnosis and treatment options for both cardiovascular syphilis as well as coronary ostial stenosis. Finally, we present the findings of case reports in patients who had syphilitic aortitis with coronary ostial stenosis and their outcomes.
- Published
- 2021
41. Impending Aortic Rupture in a Patient with Syphilitic Aortitis
- Author
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Aniko Mornos, Mioara Cocora, Mihai-Andrei Lazar, and Dan Nechifor
- Subjects
medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,tertiary syphilis ,Bentall procedure ,aortic rupture ,Case Report ,030204 cardiovascular system & hematology ,Chest pain ,03 medical and health sciences ,Aortic aneurysm ,0302 clinical medicine ,medicine ,Pharmacology (medical) ,030212 general & internal medicine ,Aortic rupture ,Aortic dissection ,business.industry ,Public Health, Environmental and Occupational Health ,Pericardial fluid ,Hematology ,General Medicine ,Syphilitic aortitis ,medicine.disease ,Surgery ,cardiovascular system ,giant aortic aneurysm ,Differential diagnosis ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business - Abstract
We report the case of a 48-year-old man, admitted for atrial fibrillation with rapid heart rate and intense chest pain. A quick evaluation revealed a giant aortic aneurysm with severe aortic regurgitation and pericardial fluid without a trace of aortic dissection. Because of high suspicion of aortic rupture, an emergency surgery was planned, and a Bentall procedure was performed. On examination of the aortic wall revealing vertical wrinkling with a tree bark aspect, suspicion of syphilitic aortitis arose. The diagnosis was confirmed through postoperative serologic testing and histological examination. Histopathologic differential diagnosis, special treatment and follow-up are presented.
- Published
- 2021
42. Cerebral syphilitic gumma presenting with intracranial gumma and pathologic vertebrae fractures
- Author
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Kavya Mirchia, Ryan Thibodeau, Matthew Klumpp, Amar Swarnkar, Abtin Jafroodifar, and Atin Goel
- Subjects
lcsh:Medical physics. Medical radiology. Nuclear medicine ,medicine.medical_specialty ,lcsh:R895-920 ,Case Report ,Tertiary Syphilis ,030218 nuclear medicine & medical imaging ,Neurosyphilis ,03 medical and health sciences ,0302 clinical medicine ,Magnetic resonance imaging of the brain ,Gumma ,Biopsy ,medicine ,Radiology, Nuclear Medicine and imaging ,Treponema pallidum ,Syphilitic bone disease ,medicine.diagnostic_test ,business.industry ,Leptomeninges ,Tertiary syphilis ,medicine.disease ,Cerebral syphilitic gumma ,medicine.anatomical_structure ,Frontal bone ,Central nervous system ,Thoracic vertebrae ,Radiology ,business ,030217 neurology & neurosurgery - Abstract
A 37-year-old female was admitted with worsening neurologic function. On arrival from an outside hospital, the patient was obtunded and intubated. Magnetic resonance imaging of the brain revealed nodular enhancement of the leptomeninges, intracranial osteolytic lesions, and diffuse vasogenic edema causing mass effect. Imaging of the thoracic spine revealed pathologic compression fractures of 4 thoracic vertebrae. On review of the patient's electronic medical record, the patient had previously received treatment for secondary syphilis with intramuscular benzathine penicillin G. Surgical biopsies of the frontal bone and dura showed diffuse, chronic inflammation while a biopsy of the adjacent brain parenchyma revealed replicating spirochetes. The patient was subsequently prescribed dexamethasone and benzathine penicillin G. She regained neurologic function but later signed out against medical advice without completing her treatment regimen.
- Published
- 2021
43. The Cave
- Author
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Hopkins, Lisa and Hopkins, Lisa
- Published
- 2007
- Full Text
- View/download PDF
44. 'Praying to Cupid for a Cure': Venereal Disease, Prostitution, and the Marriage Market in Emma
- Author
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Heydt-Stevenson, Jillian and Heydt-Stevenson, Jillian
- Published
- 2005
- Full Text
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45. Micro-CT evaluation of historical human skulls presenting signs of syphilitic infection
- Author
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Gerhard W. Weber, Martin Dockner, Maria Teschler-Nicola, Peter Pietschmann, Michael L. Pretterklieber, Sabine Fraberger, and Eduard Winter
- Subjects
medicine.medical_specialty ,Tertiary Syphilis ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,Syphilis ,Treponema pallidum ,030212 general & internal medicine ,Micro-computed tomography ,Treponema ,biology ,business.industry ,Skull ,Historical pathological-anatomical collection ,Sclerotic reorganization ,Cortical bone alterations ,Cortical thinning ,Anatomical pathology ,Bone structure ,X-Ray Microtomography ,General Medicine ,Anatomy ,biology.organism_classification ,medicine.disease ,Skeleton (computer programming) ,medicine.anatomical_structure ,Cortical porosity ,Original Article ,Cortical bone ,business ,030217 neurology & neurosurgery - Abstract
Summary Background In tertiary syphilis, Treponema pallidum triggers the formation of granulomatous nodules in various organs of the human body. Within the skeleton, predominantly in the skull and long bones, these characteristic syphilitic lesions cause typical patterns of bone damage. In this study, micro-computed tomography (µ-CT) was used to assess the microarchitecture of these osseous defects in untreated syphilitic skull bones. Material and methods Bone structure of 30 macerated human skulls was noninvasively examined by means of µ-CT images (Viscom X8060 NDT). A total of 20 specimens showing typical morphological signs of syphilis were provided by the Collection of Anatomical Pathology of the Museum of Natural History in Vienna. They were compared to 10 macerated control skulls provided by the Division of Anatomy of the Medical University of Vienna. Results All samples affected by syphilis showed perforating defects and increased porosity. Furthermore, we observed sclerotic reorganization and complete loss of the cortical bone in 80% of infected cases. Cortical thinning occurred in 75%. Conclusion Our findings revealed extensive micromorphological bone destruction and a broad variability of osseous manifestations of (tertiary) syphilis.
- Published
- 2021
46. Syphilitic Spinal Disease: An Old Nemesis Revisited. A Case Series and Review of Literature
- Author
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Shermyn Xiumin Neo, Hui Jin Chiew, Pei Xuan Koh, Zhiyong Chen, Monica Saini, and Dinesh Singh
- Subjects
Microbiology (medical) ,medicine.medical_specialty ,Cord ,business.industry ,Public Health, Environmental and Occupational Health ,Meninges ,Penicillins ,Dermatology ,Tertiary Syphilis ,Spinal disease ,medicine.disease ,Myelopathy ,Infectious Diseases ,medicine.anatomical_structure ,Tabes dorsalis ,Gumma ,medicine ,Humans ,Spinal Diseases ,Syphilis ,Treponema pallidum ,business ,Vertebral column - Abstract
Syphilitic spinal disease is a rare condition caused by the spirochete Treponema pallidum, either from direct spirochete involvement of the cord, or as a consequence of indirect spirochete involvement of the meninges, blood vessels, or the vertebral column. Following the introduction of penicillin therapy in the 1940s, it has become an increasingly rare condition. We report three challenging cases of syphilitic spinal disease presenting as myelopathy - one with an extra-axial gumma of tertiary syphilis causing cord compression, and two with tabes dorsalis complicated by tabetic spinal neuroarthropathy - each presenting a diagnostic dilemma to their treating physicians. We also review the literature for updates on modern investigative modalities, and discuss pitfalls physicians need to avoid in order to arrive at the diagnosis.
- Published
- 2021
47. Tertiary Syphilis Involving the Larynx: A Rare Case Report
- Author
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Wesley D. Carlisle, Bhushan Thakkar, Samantha Redfield, and Andrew T. Meram
- Subjects
Larynx ,medicine.medical_specialty ,medicine.anatomical_structure ,business.industry ,Rare case ,medicine ,General Medicine ,business ,Tertiary Syphilis ,Dermatology - Published
- 2021
48. A rare case of palatal perforation due to tertiary syphilis.
- Author
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Natarajan, Surya Besant and Balaann, Krishna Prasanth
- Subjects
- *
SYPHILIS , *INTESTINAL perforation , *ARTIFICIAL palates , *SEXUALLY transmitted diseases - Published
- 2022
- Full Text
- View/download PDF
49. Deformowanie prawdy medyczno-historycznej o chorobie i śmierci króla Polski Jana III Sobieskiego.
- Author
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GATH, ISAK
- Subjects
PHYSICIANS ,SYPHILIS ,CONGESTIVE heart failure ,CARDIOVASCULAR system ,MEDICAL care - Abstract
Copyright of Archives of the History & Philosophy of Medicine / Archiwum Historii i Filozofii Medycyny is the property of Polskie Towarzystwo Historii Medycyny i Farmacji and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2017
50. A Rare Case of Neurosyphilis Manifesting as Psychosis in an HIV-Negative Patient.
- Author
-
Yazigi A, Yazigi M, and Zainah H
- Abstract
Neurosyphilis is a rare disease now, given the availability of antibiotics to treat syphilis. Patients with neurosyphilis could present with psychiatric symptoms. We present a rare case of neurosyphilis with only psychiatric symptoms. The patient was a 49-year-old male who presented with self-neglect and was not interacting with others. Treponema antibodies were positive, and rapid plasma reagin (RPR) was 1:512 with a positive venereal disease research laboratory test (VDRL) in the cerebrospinal fluid. The patient was treated with an IV penicillin regimen for neurosyphilis and improved remarkably with a return to baseline on follow-up., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2023, Yazigi et al.)
- Published
- 2023
- Full Text
- View/download PDF
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