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The purpose of this three-year observational study was to analyze the ventilatory efficiency and breathing pattern in world-class professional cyclists. Twelve athletes (22.61 ± 3.8 years; 177.38 ± 5.5 cm; 68.96 ± 5.5 kg and VO 2max 75.51 ± 3.3mL kg −1 min −1 ) were analyzed retrospectively. For each subject, respiratory and performance variables were recorded during incremental spiroergometry: oxygen uptake (VO 2 ), carbon dioxide output (VCO 2 ), pulmonary ventilation (VE), tidal volume (Vt), breathing frequency ( f R ), driving (Vt/Ti), timing (Ti/Ttot), peak power output (PPO) and maximum oxygen uptake (VO 2max ). Ventilatory efficiency (VE/VCO 2 slope) was calculated from the beginning of exercise testing to the second ventilatory threshold (VT 2 ). The VE/VCO 2 slope was unaffected during the study period (24.63 ± 3.07; 23.61 ± 2:79; 24:89 ± 2:61) with a low effect size (ES = 0.04). The PPO improved significantly in the third year (365 ± 33.74; 386.36 ± 32.33; 415.00 ± 24.15) ( p < 0.05). The breathing pattern variables, Vt/Ti and Ti/Ttot, did not change significantly over the three year period (ES = 0.00; ES = 0.03 respectively). These findings suggest that changes in cycling performance in world-class professional cyclists do not modify breathing variables related to the control of ventilatory efficiency. [ABSTRACT FROM AUTHOR]

Background: Very few studies have analysed heart rate (HR) with regard to music playing, and the scarce evidence available is controversial. The purpose of this study was to analyse the HR response of professional musicians during their real-work activity. Methods: Sixty-two voluntary professional musicians (20 women, 42 men), whose ages ranged between 15 and 71 years old, underwent the test while playing their instruments in real life scenarios, i.e. rehearsals, practice and public concerts. The musicians carried Sport Tester PE4000 (Polar(r), Finland) pulsometers to record their HR. In order to compare data from differently aged subjects we calculated their Maximum Theoretical Heart Rate (MTHR). Later on we found out the MTHR percentages (%MTHR) corresponding to the registered HR of each subject in different situations. The value of the MTHR for every musician was obtained by means of the 220 - age (in years) formula. Results: Throughout the HR recordings, we have observed that musicians present a heightened HR while playing (in soloists, mean and maximum HR were 72% and 85%MTHR, respectively). Cardiac demand is significantly higher in concerts than in rehearsals while performing the same musical piece. The HR curves corresponding to the same musician playing in repeated concerts (with the same programme) were similar. Conclusion: The cardiac demand of a professional instrument player is higher than previously described, much greater than what would be expected from a supposedly sedentary activity. [ABSTRACT FROM AUTHOR]

Abstract: Mitochondrial function is absolutely necessary to supply the energy required for muscles, and germ line mutations in mitochondrial genes have been related with impaired cardiac function and exercise intolerance. In addition, alleles at several polymorphic sites in mtDNA define nine common haplogroups, and some of these haplogroups have been implicated in the risk of developing several diseases. In this study, we analysed the association between mtHaplogroups and the capacity to reach the status of elite endurance athlete. DNA was obtained from blood leukocytes of 95 Spanish elite endurance athletes and 250 healthy male population controls. We analysed eight mitochondrial polymorphisms and the frequencies were statistically compared between elite athletes and controls. Haplogroup T, specifically defined by 13368A, was significantly less frequent among elite endurance athletes (p =0.012, Fisher’s exact test). Our study suggests that allele 13368A and mitochondrial haplogroup T might be a marker negatively associated with the status of elite endurance athlete. This mitochondrial variant could be related with a lower capacity to respond to endurance training, through unknown mechanisms involving a less efficient mitochondrial workload. [Copyright &y& Elsevier]

A sedentary lifestyle and Olympic participation are contrary risk factors for global mortality and incidence of cancer and cardiovascular disease. Extracellular vesicle miRNAs have been described to respond to exercise. No molecular characterization of young male sedentary people versus athletes is available; so, our aim was to identify the extracellular vesicle miRNA profile of chronically trained young endurance and resistance male athletes compared to their sedentary counterparts. A descriptive case–control design was used with 16 sedentary young men, 16 Olympic male endurance athletes, and 16 Olympic male resistance athletes. Next‐generation sequencing and RT‐qPCR and external and internal validation were performed in order to analyze extracellular vesicle miRNA profiles. Endurance and resistance athletes had significant lower levels of miR‐16‐5p, miR‐19a‐3p, and miR‐451a compared to sedentary people. Taking all together, exercise‐trained miRNA profile in extracellular vesicles provides a differential signature of athletes irrespective of the type of exercise compared to sedentary people. Besides, miR‐25‐3p levels were specifically lower in endurance athletes which defines its role as a specific responder in this type of athletes. In silico analysis of this profile suggests a role in adaptive energy metabolism in this context that needs to be experimentally validated. Therefore, this study provides for the first time basal levels of circulating miRNA in extracellular vesicles emerge as relevant players in intertissue communication in response to chronic exercise exposure in young elite male athletes. Highlights: An extracellular vesicle miRNA profile defined by next‐generation sequencing differentiates athletes compared to sedentary young males.Extracellular vesicle miR‐16‐5p, miR‐19a‐3p, and miR‐451a were lower in athletes irrespective of their sport disciplines compared to sedentary young males.Extracellular vesicle miR‐25‐3p was specifically lower in endurance athletes compared to sedentary young males.Energy metabolism and structural pathways are the main regulated ones based on extracellular vesicle miRNA profile. [ABSTRACT FROM AUTHOR]

Purpose: Physical activity (PA) provides multiple health-related benefits in children and adolescents, however, at present, the majority of young people are insufficiently physically active. The aim of this study was to evaluate if neighborhood walkability and/or socio-economic status (SES) could affect the practice of walking, play outdoors and sports practice in a representative sample of Spanish children and adolescents. Methods: A sample of 4092 youth (aged 8–16 years old) from 245 primary and secondary schools in 121 localities from each of the 17 Spanish autonomous communities participated in the study. Walk Score was used to evaluate walkability of the neighborhood and household income was used as an indicator of SES. A 7-item self-reported validated questionnaire, was used to assess PA levels, and in a subsample of 10% of the participants, randomly selected from the entire sample, PA was objectively measured by accelerometers. Results: Youth from more walkable areas reported more minutes walking per day compared with those from less walkable neighborhoods (51.4 vs 48.8 minutes, respectively). The lowest average minutes spent in playing outdoors was found among participants from low-SES and low-walkable neighborhoods. Neighborhood SES influenced on the participation in team sports during the weekend, being this participation higher in high SES neighborhoods. Conclusion: Providing high walkable environments seems a good strategy to promote PA regardless SES levels. It seems that improving the walkability is a key component to partially overcome the SES inequalities, especially in urban areas with low SES. High-SES environments can offer better sports facilities and more organized physical activities than low-SES ones. [ABSTRACT FROM AUTHOR]

The objectives of the study were to evaluate the influence of a whole training season on 6-sulfatoxymelatonin (αMT6s) and citrate excretion in 12 elite swimmers. Urine samples were obtained (before bedtime and after waking up) at the beginning of the season, basic training, macrocycle I, tapering and macrocycle II stages. For αMT6s, at basic training, mainly with aerobic training, the evening concentrations were significantly lower (P < 0.01; P < 0.05) than at the beginning, tapering and macrocycle II stages. At macrocycle II stage, with the maximal training workload, the total sum (evening plus morning) was significantly higher (P < 0.05) than at the beginning, basic training and macrocycle I stages. The ratio (morning/evening) that represents the capacity to produce melatonin at night depending on the evening values at the basic training stage and the nocturnal increment at the macrocycle II stage were significantly higher (P < 0.01) than at all other stages. Citrate morning values at basic training and tapering stages were significantly lower (P < 0.01) than in the evening indicating that a metabolic recuperation took place. The total sum significantly decreased (P < 0.05) as the aerobic training progressed from the beginning to macrocycle I. The basic training ratio (morning/evening) was significantly lower compared to the beginning and macrocycle II stages, and the nocturnal increment was significantly higher (P < 0.05) compared to the beginning. Melatonin and citrate represent complementary markers that could be used to evaluate the assimilation of the training workload by noninvasive methods. [ABSTRACT FROM AUTHOR]

In elite basketball, the high demands of competition and training require a detailed follow-up of the effects on the player's performance and health. Controlling these effects could improve the knowledge about the players' recovery process and allow a better design of their individual workloads. Aim. To describe the behavior of the total testosterone serum levels (T), cortisol (C) and T/C ratio. Methodology: 8 blood samples were collected during the whole season of an elite basketball team (n=8) of the First Spanish Division (ACB). The samples were taken every 4-6 weeks, at 8:00 AM, after 24-36 hours of post-game recovery. Results: T increases after 4 after 3.5 days of rest (6th vs. 1st, p=0.039; 6th vs. 5th, p=0.041) and decreases significantly at the end of the season (8th vs. 7th, p=0.003). C does not show significant variation along the season. T/C ratio shows a significant decrease at the end of the season (8th vs. 1st, p=0.021; 8th vs. 7th, p=0.0l7) and in VarT/C (8th vs. 1st, p=0.005; 8th vs. 7th, p=0.036). Conclusions: Concentration values as well as percentages of variation are useful indicators to describe the studied parameters. T/C ratio and/or T could be used as recovery state indicators and could even induce, in conjunction with other indicators, necessary actions to optimize individual workloads. Future investigations should compare these variations to objective workload parameters and/or other hormonal modulators. [ABSTRACT FROM AUTHOR]

Background: Validation of self-reported tools, such as physical activity (PA) questionnaires, is crucial. The aim of this study was to determine test-retest reliability, internal consistency, and the concurrent, construct, and predictive validity of the short semi-quantitative Physical Activity Unit 7 item Screener (PAU-7S), using accelerometry as the reference measurement. The effect of linear calibration on PAU-7S validity was tested. Methods: A randomized sample of 321 healthy children aged 8–16 years (149 boys, 172 girls) from the nationwide representative PASOS study completed the PAU-7S before and after wearing an accelerometer for at least 7 consecutive days. Weight, height, and waist circumference were measured. Cronbach alpha was calculated for internal consistency. Test-retest reliability was determined by intra-class correlation (ICC). Concurrent validity was assessed by ICC and Spearman correlation coefficient between moderate to vigorous PA (MVPA) derived by the PAU-7S and by accelerometer. Concordance between both methods was analyzed by absolute agreement, weighted kappa, and Bland-Altman statistics. Multiple linear regression models were fitted for construct validity and predictive validity was determined by leave-one-out cross-validation. Results: The PAU-7S overestimated MVPA by 18%, compared to accelerometers (106.5 ± 77.0 vs 95.2 ± 33.2 min/day, respectively). A Cronbach alpha of 0.76 showed an acceptable internal consistency of the PAU-7S. Test-retest reliability was good (ICC 0.71 p < 0.001). Spearman correlation and ICC coefficients of MVPA derived by the PAU-7S and accelerometers increased from 0.31 to 0.62 and 0.20 to 0.62, respectively, after calibration of the PAU-7S. Between-methods concordance improved from a weighted kappa of 0.24 to 0.50 after calibration. A slight reduction in ICC, from 0.62 to 0.60, yielded good predictive validity. Multiple linear regression models showed an inverse association of MVPA with standardized body mass index (β − 0.162; p < 0.077) and waist to height ratio (β − 0.010; p < 0.014). All validity dimensions were somewhat stronger in boys compared to girls. Conclusion: The PAU-7S shows a good test-retest reliability and acceptable internal consistency. All dimensions of validity increased from poor/fair to moderate/good after calibration. The PAU-7S is a valid instrument for measuring MVPA in children and adolescents. Trial registration: Trial registration numberISRCTN34251612. [ABSTRACT FROM AUTHOR]

The "Century XXI" Project is a seven-year intervention sport program performed among the best Spanish youth basketball players, who were assigned to one of the following intervention groups based on the following criteria: age, position, mature level, and origin in the country. The study was performed (1996-2001) with a total of 90 players. The main purposes of this study were: a) to describe anthropometric and performance characteristics of top youth international male basketballers in the Spanish national academy; and b) to analyze differences among positions. Insummary, the main findings of this study were: a) the anthropometry presented significant differences between groups under (U-) 14 and U-17; and b) in the U-17 group centers presented more arm span. In our study, the most significant changes are in U-16 vs U-14 and U-15 in strength body up values, and the best result in endurance capacity took place in June of the fourth year. Within this context, the results of the present study may be useful for strength and conditioning coaches to plan their programs with youth basketball players. [ABSTRACT FROM AUTHOR]

Acute exercise seems to increase total plasma homocysteine (tHcy); since this variable associated with cardiovascular risk, it is important to understand the determinants of its response to all types of exercise. The aim of this study was to examine the impact of cycling at 2 different rates of muscle contraction on the complete tHcy kinetics. Eight young sedentary males were required to complete 2 isocaloric (400 kcal) acute exercise trials at 50% peak oxygen uptake on separate occasions at 50 or 80 rpm. Blood samples were drawn at different points before (4 h before exercise and immediately before exercise), during (10, 20, 30, 45, and 60 min during exercise), and after exercise (immediately and 19 h after exercise). Dietary and lifestyle factors were controlled during the research. Maximum tHcy occurred during exercise for both conditions (50 rpm: 11.4 ± 2.7 μmol·L-1; 80 rpm: 10.8 ± 3.2 μmol·L-1). From this point onwards tHcy declined until the cessation of exercise and continued descending below pre-exercise values at 19 h postexercise ( p < 0.05). No hyperhomocysteinemia were observed at any sampling point in both trials. In conclusion, the different muscular contraction frequency during exercise has no impact on tHcy during an acute bout of exercise in sedentary individuals, when at least 400 kcal are spent during exercise and the nutritional status for folate, B12, and B6 is adequate. This information is relevant to further inform healthy exercise prescription, not only in terms of duration and intensity of exercise, but also taking into account frequency of contraction. [ABSTRACT FROM AUTHOR]

There is not enough evidence of positive effects of compression therapy on the recovery of soccer players after matches. Therefore, the objective was to evaluate the influence of different types of compression garments in reducing exercise-induced muscle damage (EIMD) during recovery after a friendly soccer match. Eighteen semi-professional soccer players (24 ± 4.07 years, 177 ± 5 cm; 71.8 ± 6.28 kg and 22.73 ± 1.81 BMI) participated in this study. A two-stage crossover design was chosen. Participants acted as controls in one match and were assigned to an experimental group (compression stockings group, full-leg compression group, shorts group) in the other match. Participants in experimental groups played the match wearing the assigned compression garments, which were also worn in the 3 days post-match, for 7 h each day. Results showed a positive, but not significant, effect of compression garments on attenuating EIMD biomarkers response, and inflammatory and perceptual responses suggest that compression may improve physiological and psychological recovery. [ABSTRACT FROM AUTHOR]

Background: The goal was to compare the achievement goal profile and the motivational regulations of one world-class and two high-level athletes during their preparation for the Rio Olympic Games. Method: Three kayakers from the Spanish Olympic team participated. One (P1) and two (P2) were high-level athletes: finalists at the World and European championships, and several national championships. Participant three (P3) was a world-class athlete: 2 Olympic medals, 7 World championship medals, 4 European championship medals, and several national championships. Before and after three training sessions and 4 international competitions (including World and European championships) all participants completed a questionnaire to assess their achievement goal orientation, dominance and pursuit, as well as their motivational regulation. Generalized estimated equations (GEE) analysis was used to assess significant differences between subjects. Results: P3 had lower performance-approach goal orientation, stronger mastery-approach goal dominance, lower performance-approach and performance-avoidance goal pursuit, higher mastery-avoidance goal pursuit and lower controlled motivation than the other two participants. Conclusion: Our world-class athlete has a strong mastery-approach achievement goal dominant profile, and a low performance-oriented profile (both approach and avoidance) and controlled motivation. This profile should be confirmed in similar athletes to help coaches and their young athletes make appropriate decisions. [ABSTRACT FROM AUTHOR]

Purpose: The aim was to identify benefits of compression garments used for recovery of exercised-induced muscle damage. Methods: Computer-based literature research was performed in September 2015 using four online databases: Medline (PubMed), Cochrane, WOS (Web Of Science) and Scopus. The analysis of risk of bias was completed in accordance with the Cochrane Collaboration Guidelines. Mean differences and 95% confidence intervals were calculated with Hedges' g for continuous outcomes. A random effect meta-analysis model was used. Systematic differences (heterogeneity) were assessed with I² statistic. Results: Most results obtained had high heterogeneity, thus their interpretation should be careful. Our findings showed that creatine kinase (standard mean difference = -0.02, 9 studies) was unaffected when using compression garments for recovery purposes. In contrast, blood lactate concentration was increased (standard mean difference = 0.98, 5 studies). Applying compression reduced lactate dehydrogenase (standard mean difference = -0.52, 2 studies), muscle swelling (standard mean difference = -0.73, 5 studies) and perceptual measurements (standard mean difference = -0.43, 15 studies). Analyses of power (standard mean difference = 1.63, 5 studies) and strength (standard mean difference = 1.18, 8 studies) indicate faster recovery of muscle function after exercise. Conclusions: These results suggest that the application of compression clothing may aid in the recovery of exercise induced muscle damage, although the findings need corroboration. [ABSTRACT FROM AUTHOR]

The article reports on research which investigated the effects playing time, positional role and phase of the season had on the biomarkers testosterone and cortisol in 20 professional male basketball players. They found that players who played between 13 and 25 minutes per game showed the highest levels of testosterone and cortisol, that players showed the most catabolic or stressed hormonal state in March and April and that is necessary to take into account playing time and position when evaluating biomarkers.

The article assesses the ACE gene polymorphism and erythropoietin (EPO) in endurance athletes at moderate altitude. Significantly, erythropoietic activity was measured in endurance athletes following natural exposure to altitude as well as the EPO levels and hemoglobin concentrations. Results have indicated that EPO levels have significantly increased above baseline concentration following exposure to moderate altitude. Finally, ACE gene polymorphism does not influence EPO activity in endurance athletes after short-term exposure to moderate altitude.

Aims: The aim of this investigation was to examine the thyroid hormone levels of professional cyclists during a 3-week stage competition (Vuelta a España 1998). Methods: The study population was made up of 16 male cyclists from two world-leading professional teams. Four blood samples were drawn (between 07:00 and 09:00 a.m.) from each participant before and at the end of the 1st, 2nd and 3rd weeks of competition. 3,5,3′(-Triiodothyronine (T[sub 3] ), free T[sub 3] (FT[sub 3] ), thyroxine (T[sub 4] ), free T[sub 4] (FT[sub 4] ) and thyroid-stimulating hormone (TSH) were determined in each blood sample by radioimmunoassay. Results: Serum T[sub 4] , FT[sub 4] and FT[sub 3] levels showed a significant increase (p < 0.05) by the last week of competition while concentrations of TSH and T[sub 3] remained unchanged. Conclusion: In conclusion, 3 weeks of competition provokes changes in basal thyroid hormone concentrations in professional road cyclists.Copyright © 2002 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]

The aim of this study is to evaluate if screen time and parents' education levels are associated with adherence to a Mediterranean dietary pattern. This cross-sectional study analyzed a representative sample of 3333 children and adolescents (8 to 16 years) included in the Physical Activity, Sedentarism, lifestyles and Obesity in Spanish youth (PASOS) study in Spain (which ran from March 2019 to February 2020). Data on screen time (television, computer, video games, and mobile phone) per day, Mediterranean diet adherence, daily moderate or vigorous physical activity, and parents' education levels were gathered using questionnaires. A descriptive study of the variables according to sex and parents' education level was performed. Logistic regression models (adjusted by sex and weight status) were fitted to evaluate the independent association between screen time and Kids' level of adherence to the Mediterranean diet (KIDMED) index, as well as some of its items. A greater amount of screen time was associated with worse adherence to the Mediterranean diet; a lower consumption of fruit, vegetables, fish, legumes, and nuts; and a greater consumption of fast food, sweets, and candies. A lower parents' education level was associated with worse adherence to the Mediterranean diet. It is necessary to promote the responsible, limited use of screen time, especially in children with parents with a lower education level. [ABSTRACT FROM AUTHOR]