Search

Your search keyword '"Terpening, Zoe"' showing total 50 results
Start Over Author "Terpening, Zoe"
50 results on '"Terpening, Zoe"'

8. Actigraphic and melatonin alignment in older adults with varying dementia risk.

Author

Menczel Schrire, Zoe, Gordon, Christopher J, Palmer, Jake R, Murray, Jade, Hickie, Ian, Rogers, Naomi L., Lewis, Simon JG, Terpening, Zoe, Pye, Jonathon E, Naismith, Sharon L, and Hoyos, Camilla M

Subjects
DISEASE risk factors, OLDER people, MELATONIN, BIOMARKERS, CIRCADIAN rhythms, SLEEP deprivation
Abstract

Circadian rhythms alter with ageing and may be aetiologically linked to neurodegeneration. This study explored the association between clinical markers and 1) dim light melatonin onset (DLMO) time and 2) phase angle derived from sleep midpoint, in older adults with varying dementia risks. Participants completed 14 days of actigraphy followed by in-lab measurement of salivary melatonin, from which DLMO time and phase angle were computed. Eighty participants (age = 65.5, SD = 9.6), 44 males (55%), MMSE (28.6, SD = 1.5) were included in the analysis. Sex (t = 2.15, p =.04), sleep onset (r = 0.49, p <.001) and midpoint (r = 0.44, p <.001) also correlated with DLMO time. Multiple linear regression showed chronotype, average actigraphy-derived light exposure during the DLMO window (window 2 h prior to DLMO to 2 h post), early biological day (6–10 h post DLMO time) and late biological day (10–14 h post DLMO time) were predictive of DLMO time (adjusted R2 = 0.75). Sleep offset, depression severity, average light exposure during the early biological night and early and late biological day were shown to be predictive variables in the estimation of phase angle (adjusted R2 = 0.78). The current study highlights the potential use of clinical variables, such as actigraphy-derived light, as circadian markers in ageing which could be easily implemented into existing clinical practice and could yield potential targets focusing on chronotherapeutic interventions. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

14. Cluster‐Randomized Trial of Thrombolysis Implementation Support in Metropolitan and Regional Australian Stroke Centers: Lessons for Individual and Systems Behavior Change

Author

Levi, Christopher R., primary, Attia, John A., additional, D'Este, Cate, additional, Ryan, Annika E., additional, Henskens, Frans, additional, Kerr, Erin, additional, Parsons, Mark W., additional, Sanson‐Fisher, Robert W., additional, Bladin, Christopher F., additional, Lindley, Richard I., additional, Middleton, Sandy, additional, Paul, Christine L., additional, Anderson, Craig, additional, Ang, Tim, additional, Bivard, Andrew, additional, Cadigan, Greg, additional, Celestino, Sherisse, additional, Coles, Tim, additional, Corbett, Alistair, additional, Dark, Lisa, additional, Day, Susan, additional, Dennett, Jennifer, additional, Donnan, Geoffrey, additional, Evans, Malcolm, additional, Fernando, Kavisha, additional, Geraghty, Richard, additional, Gerraty, Richard, additional, Grady, Alice, additional, Grimley, Rohan, additional, Gu, Jason, additional, Hankey, Graeme J., additional, Hoffman, Kim, additional, Hughes, James, additional, Ip, Jerome, additional, Jenkins, Bronwyn, additional, Jones, Mark, additional, Jude, Martin, additional, Kaauwai, Lara, additional, Kanard, Malcolm, additional, Kinchington, Matthew, additional, Krause, Martin, additional, Kuhle, Sarah, additional, Levy, Stanley, additional, Longworth, Mark, additional, Macdonald, Beverley, additional, Mackey, Elizabeth, additional, Mandaleson, Krishna, additional, Miteff, Ferdi, additional, Mohr, Katherine, additional, Moore, Stephen, additional, Morris, Kristy, additional, O'Brien, Elizabeth, additional, Oldmeadow, Christopher, additional, Paddock, Bruce, additional, Parrey, Kim, additional, Peake, Rachel, additional, Russell, Michelle, additional, Stevenson, Margaret, additional, Taneja, Sanjeev, additional, Teasdale, Natalie, additional, Terpening, Zoe, additional, Van Berkel, Anne, additional, Watson, John D. G., additional, Weiner, Yolande, additional, Wijeratne, Tissa, additional, Wilson, Alison, additional, and Wolfe, Nigel, additional

Published
2020
Full Text
View/download PDF

15. Nocturnal Hypoxemia Is Associated with Altered Parahippocampal Functional Brain Connectivity in Older Adults at Risk for Dementia

Author

Naismith, Sharon L., primary, Duffy, Shantel L., additional, Cross, Nathan, additional, Grunstein, Ron, additional, Terpening, Zoe, additional, Hoyos, Camilla, additional, D’Rozario, Angela, additional, Lagopoulos, Jim, additional, Osorio, Ricardo S., additional, Shine, James M., additional, and McKinnon, Andrew C., additional

Published
2020
Full Text
View/download PDF

18. Substantiating synesthesia: a novel aid in a case of grapheme-colour synesthesia and concomitant dyscalculia.

Author

Berger, Joshua J, Harris, Irina M, Whittingham, Karen M, Terpening, Zoe, and Watson, John D G

Subjects
SYNESTHESIA, ACALCULIA, RESEARCH, COLOR vision, RESEARCH methodology, MEDICAL cooperation, EVALUATION research, PRODUCT design, COMPARATIVE studies, VISUAL perception, READING
Abstract

Here we present the case of SP, a 21-year-old female with life-long dyscalculia. SP was subsequently diagnosed with grapheme-color synesthesia, a diagnosis that serendipitously catalyzed our development of a novel aid:The digit-color calculator (DCC). The DCC substantiates SP's color concurrents, dramatically ameliorating her difficulties with basic calculations. We envisage the DCC and its analogues may assist others in educational settings, particularly if they experience difficulties with the acquisition of literacy and numeracy. Further devices that leverage synesthesia may also have the potential to improve the quality of life for others with trait synesthesia regardless of concomitant disorder. [ABSTRACT FROM AUTHOR]

Published
2020
Full Text
View/download PDF

22. Functional Connectivity in the Default Mode Network is Reduced in Association with Nocturnal Awakening in Mild Cognitive Impairment

Author

McKinnon, Andrew C., primary, Duffy, Shantel L., additional, Cross, Nathan E., additional, Terpening, Zoe, additional, Grunstein, Ron R., additional, Lagopoulos, Jim, additional, Batchelor, Jennifer, additional, Hickie, Ian B., additional, Lewis, Simon J.G., additional, Shine, James M., additional, and Naismith, Sharon L., additional

Published
2017
Full Text
View/download PDF

23. "Sleep Well, Think Well" Group Program for Mild Cognitive Impairment: A Randomized Controlled Pilot Study.

Author

Naismith, Sharon L, Pye, Jonathon, Terpening, Zoe, Lewis, Simon, and Bartlett, Delwyn

Subjects
MILD cognitive impairment, COGNITIVE testing, SLEEP, SLEEP spindles, PILOT projects, OLDER people
Abstract

Objective/Background: Sleep-wake disturbance is associated with poor cognitive functioning and several other adverse outcomes that increase dementia risk in older adults. Targeting sleep-wake disturbance in individuals at risk for dementia may be an important treatment. This study evaluated the efficacy of a four-session multicomponent group intervention for participants with mild cognitive impairment (MCI). Participants: Thirty-five older adults with MCI (mean age = 69.7 years, SD = 9.1), were recruited. MCI was determined via consensus from neuropsychological, medical, and neurological review. Methods: Participants were randomized to the "Sleep Well, Think Well" (SWTW) group condition or a passive control group. The SWTW group received four fortnightly face-to-face sessions conducted by an experienced sleep psychologist and neuropsychologist. The control group received written material detailing strategies to improve sleep quality. Both groups received fortnightly coaching phone calls. The primary outcome was subjective sleep quality, measured by the Pittsburgh Sleep Quality Index (PSQI). Secondary outcomes included actigraphy sleep measures, daytime sleepiness, cognitive functioning, and depression severity. Results: The SWTW intervention was associated with a large and statistically significant improvement in subjective sleep quality (Cohen's d = 0.83, p < 0.02). A moderate nonsignificant effect was evident in reducing daytime sleepiness (Cohen's d = 0.70, p =.08). No significant effects were found on actigraphy markers, depressive symptoms, or tests of cognitive functioning. Conclusions: The eight-week SWTW group intervention for MCI significantly improved subjective sleep quality when compared with a passive control condition. The program also had a moderate (nonsignificant) effect on reducing daytime sleepiness. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

25. Quantifying the effect of body mass index, age, and depression severity on 24-h activity patterns in persons with a lifetime history of affective disorders

Author

Banihashemi, Nahid, primary, Robillard, Rébecca, additional, Yang, Jean, additional, Carpenter, Joanne S., additional, Hermens, Daniel F., additional, Naismith, Sharon L., additional, Terpening, Zoe, additional, White, Django, additional, Scott, Elizabeth M., additional, and Hickie, Ian B., additional

Published
2016
Full Text
View/download PDF

31. Mild Cognitive Impairment Subtypes in Older People With Depressive Symptoms

Author

Jayaweera, Hirosha K., primary, Hickie, Ian B., additional, Duffy, Shantel L., additional, Hermens, Daniel F., additional, Mowszowski, Loren, additional, Diamond, Keri, additional, Terpening, Zoe, additional, Paradise, Matthew, additional, Lewis, Simon J. G., additional, Lagopoulos, Jim, additional, and Naismith, Sharon L., additional

Published
2015
Full Text
View/download PDF

32. 29.

Author

Bolitho, Samuel, primary, Naismith, Sharon, additional, Rajaratnam, Shanthakumar, additional, Grunstein, Ron, additional, Hodges, John, additional, Terpening, Zoe, additional, Rogers, Naomi, additional, and Lewis, Simon, additional

Published
2014
Full Text
View/download PDF

33. 4.

Author

Bolitho, Samuel, primary, Shine, James, additional, Naismith, Sharon, additional, Terpening, Zoe, additional, Grunstein, Ron, additional, Melehan, Kerri, additional, Yee, Brendon, additional, Coeytaux, Alessandra, additional, and Lewis, Simon, additional

Published
2014
Full Text
View/download PDF

47. The Relationships Between Poor Sleep Efficiency and Mild Cognitive Impairment in Parkinson Disease.

Author

Gunn, David G., Naismith, Sharon L., Terpening, Zoe, and Lewis, Simon J. G.

Subjects
PARKINSON'S disease, COGNITION disorders, SLEEP disorders, INSOMNIA, TREMOR, HYPOKINESIA, POSTURE disorders
Abstract

Background: Mild cognitive impairment (MCI) and sleep disturbances are common features in Parkinson disease (PD). This study sought to investigate whether patients with MCI in PD (PD-MCI) have more pronounced sleep disturbance compared to those without PD-MCI and whether phenotypic presentations differ according to the PD-MCI subtypes.Methods: A total of 95 patients with idiopathic PD (53 meeting criteria for PD-MCI and 42 who were not cognitively impaired) and 22 controls underwent neurological and neuropsychological examination. They wore actigraphy watches for 2 weeks, from which measures of nocturnal sleep efficiency were calculated.Results: Patients with PD-MCI has significantly poorer sleep efficiency compared to those without PD-MCI. This effect was particularly apparent in those with multiple-domain PD-MCI, compared to those with single-domain PD-MCI. Furthermore, patients in the PD-MCI group had significantly more nontremor features.Conclusions: These data suggest that PD-MCI is associated with greater sleep disturbance and nontremor features of PD. This is further evidence for the potential role that sleep disturbance plays in the heterogeneity of PD. [ABSTRACT FROM AUTHOR]

Published
2014
Full Text
View/download PDF

48. Circadian Misalignment and Sleep Disruption in Mild Cognitive Impairment.

Author

Naismith, Sharon L., Hickie, Ian B., Terpening, Zoe, Rajaratnam, Shanthakumar W., Hodges, John R., Bolitho, Samuel, Rogers, Naomi L., and Lewis, Simon J.G.

Subjects
MILD cognitive impairment, ALZHEIMER'S disease, TRYPTAMINE, ALZHEIMER'S patients, RAPID eye movement sleep
Abstract

Background: While it is evident that Alzheimer's disease is associated with disturbed sleep and circadian rhythms, the extent to which such changes are evident in older people 'at risk' of developing dementia is unknown. Objective: In this study, we aimed to determine whether patients with mild cognitive impairment (MCI) demonstrated significant alterations in the timing of melatonin secretion onset and amount, as well as sleep architecture. Methods: Thirty patients with MCI and 28 age-matched controls underwent psychiatric, medical, and neuropsychological assessment, followed by overnight polysomnography and dim light melatonin onset assessment. Participants also performed an episodic memory task while in the laboratory. Dim light melatonin onset was computed using a standardized algorithm, and area under the curve was computed for melatonin secretion. Sleep architecture measures including wake after sleep onset and latency to rapid eye movement sleep were derived. Results: Patients with MCI had advanced timing of their melatonin secretion onset relative to controls, but the levels of melatonin secreted did not differ between groups. The MCI group also had greater wake after sleep onset and increased rapid eye movement sleep latency. There were differential associations between dim light melatonin onset and cognition between the two groups, with earlier dim light melatonin onset being associated with poorer memory performance in MCI patients. Conclusion: Circadian misalignment and sleep disruption is evident in patients with MCI, and is consistent with changes observed in Alzheimer's disease. Such findings could be a marker for disease trajectory, and may even be implicated in disease pathogenesis. [ABSTRACT FROM AUTHOR]

Published
2014
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results