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373 results on '"Tenhunen, M."'

8. Large Animal Model for Healthy Tissue Tolerance Study in BNCT

Author

Benczik, J., Seppälä, T., Hopewell, J., Snellman, M., Auterinen, I., Joensuu, R., Ramadan, U. Abo, Tanttu, J., Vähätalo, J., Kulvik, M., Joensuu, H., Tenhunen, M., Savolainen, S., Kallio, M., Färkkilä, M., Hawthorne, M. Frederick, editor, Shelly, Kenneth, editor, and Wiersema, Richard J., editor

Published
2001
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20. Radiation shielding study of Advanced Data and Power Management Systems (ADPMS) housing using Geant4

Author

Garcia, F., Kurvinen, K., Brander, T., Orava, R., Heino, J., Virtanen, A., Kettunen, H., and Tenhunen, M.

Subjects
Shielding (Radiation) -- Methods, Space ships -- Design and construction, Space ships -- Materials, Space vehicles -- Design and construction, Space vehicles -- Materials, Nuclear power plants -- Shielding (Radiation), Nuclear power plants -- Methods, Business, Electronics, Electronics and electrical industries
Abstract

A design goal for current space system is to reduce the mass used to enclose components of the spacecraft. One potential target is to reduce the mass of electronics and its housings. The use of composite materials, especially CFRP (Carbon Fiber Reinforced Plastic) is a well known and vastly used approach to mass reduction. A design goal, cost reduction, has increased the use of commercial (non-space qualified) electronics. These commercial circuits and other components cannot tolerate as high radiation levels as space qualified components. Therefore, the use of standard electronics components poses a challenge in terms of the radiation protection capability of the ADPMS housings. The main goal of this study is to provide insight on the radiation shielding protection produced by different configurations of CFRP tungsten laminates of epoxies and cyanate esters and then to compare them to the protection given by the commonly used aluminum. For a spacecraft operating in LEO and MEO orbits the main components of the space radiation environment are energetic electrons and protons, therefore in our study we will compare the experimental and simulation results of the radiation attenuation of different types of laminates for those particles. At the same time the experimental data has been used to validate the Geant4 model of the laminates, which can be used for future optimizations of the laminate structures. Index Terms--Advanced equipment design, carbon composite laminates, GEANT4, LEO and MEO orbits, low Z-high Z-low Z concept, radiation attenuation, shielding.

Published
2008

48. Large animal model for healthy tissue tolerance study in BNCT

Author

Benczik, Judit, Seppälä, Tiina, Hopewell, J., Snellman, M., Auterinen, Iiro, Joensuu, R., Ramadan, Usama Abo, Tanttu, J., Vähätalo, J., Kulvik, Martti, Joensuu, H., Tenhunen, M., Savolainen, Sauli, Kallio, M., Färkkilä, Markus, Hawthorne, Frederic, Shelly, Kenneth, and Wiersema, Richard

Abstract

In radiotherapy where normal brain tissue is in the treatment field there is a risk of developing late radiation side effects. Consequently, evaluation of normal tissue tolerance is critical for the application of safe and effective treatment. The biological effectiveness of the calculated physical doses must be estimated before boron neutron capture therapy (BNCT) is applied clinically. Relative biological effectiveness (RBE) is a function of the energy of particles. As a consequence of the difference in neutron spec-trums in different BNCT facilities the RBE of each beam may be different. The aim of the healthy tissue tolerance study at the Finnish Research Reactor (FiR 1) was to obtain a complete dose effect curve for beam characterisation as part of the safety studies. The effects of high linear energy transfer (LET) radiation from the 10B(n,α)7Li reaction were compared with the effects of the beam-only irradiation. A large animal model (the dog brain) was used for the estimation of the probability of late radiation reactions as a function of dose. The endpoint of the study was visible magnetic resonance image (MRI) changes in the brain.

Published
2001

50. Status of the Finnish boron neutron capture therapy (BNCT) project

Author

Iiro Auterinen, Carita Aschan, Judit Benczik, Markus Färkkilä, Pekka Hiismäki, Merja Kallio, Mika Kortesniemi, Antti Kosunen, Petri Kotiluoto, Martti Kulvik, Margit Snellman, Johanna Lampinen, Ryynänen, P., Sauli Savolainen, Marika Suominen, Tiina Seppälä, Tom Seren, Vesa Tanner, Tenhunen, M., Mika Toivonen, Jyrki Vähätalo, Hernberg, Rolf, and Saaristo, Jaana

Published
1998

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