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9. Steekmuggen in Nieuw Velp - Zuid : aanbevelingen voor beheer

Author

Schmidt, G. and ten Cate, L.

Subjects
chironomidae, Rijksinstituut voor Natuurbeheer, nematocera, waterbeheer, cecidomyiidae, hydrology, netherlands, culicidae, water resources, hydrologie, ecohydrology, nederland, watervoorraden, water management, ecologie, veluwe, ecology, ecohydrologie, gelderland
Published
1989

10. Higher Fluid Balance Increases the Risk of Death From Sepsis: Results From a Large International Audit

Author

Sakr Y., Rubatto Birri P. N., Kotfis K., Nanchal R., Shah B., Kluge S., Schroeder M. E., Marshall J. C., Vincent J. -L, E Tomas, E Amisi Bibonge, B Charra, M Faroudy, L Doedens, Z Farina, D Adler, C Balkema, A Kok, S Alaya, H Gharsallah, D Muzha, A Temelkov, G Georgiev, G Simeonov, G Tsaryanski, S Georgiev, A Seliman, S Vrankovic, Z Vucicevic, I Gornik, B Barsic, I Husedzinovic, P Pavlik, J Manak, E Kieslichova, R Turek, M Fischer, R Valkova, L Dadak, P Dostal, J Malaska, R Hajek, A Židková, P Lavicka, J Starkopf, Z Kheladze, M Chkhaidze, V Kaloiani, L Medve, A Sarkany, I Kremer, Z Marjanek, P Tamasi, I Krupnova, I Vanags, V Liguts, V Pilvinis, S Vosylius, G Kekstas, M Balciunas, J Kolbusz, A Kübler, B Mielczarek, M Mikaszewska-Sokolewicz, K Kotfis, B Tamowicz, W Sulkowski, P Smuszkiewicz, A Pihowicz, E Trejnowska, N Hagau, D Filipescu, G Droc, M Lupu, A Nica, R Stoica, D Tomescu, D Constantinescu, G Valcoreanu Zbaganu, A Slavcovici, V Bagin, D Belsky, S Palyutin, S Shlyapnikov, D Bikkulova, A Gritsan, G Natalia, E Makarenko, V Kokhno, A Tolkach, E Kokarev, B Belotserkovskiy, K Zolotukhin, V Kulabukhov, L Soskic, I Palibrk, R Jankovic, B Jovanovic, M Pandurovic, V Bumbasirevic, B Uljarevic, M Surbatovic, N Ladjevic, G Slobodianiuk, V Sobona, A Cikova, A Gebhardtova, C Jun, S Yunbo, J Dong, S Feng, M Duan, Y Xu, X Xue, T Gao, X Xing, X Zhao, C Li, G Gengxihua, H Tan, J Xu, L Jiang, Q Tiehe, Q Bingyu, Q Shi, Z Lv, L Zhang, L Jingtao, Z Zhen, Z Wang, T Wang, L Yuhong, Q Zhai, Y Chen, C Wang, W Jiang, W Ruilan, Y Chenv, H Xiaobo, H Ge, T Yan, C Yuhui, J Zhang, F Jian-Hong, H Zhu, F Huo, Y Wang, M Zhuang, Z Ma, J Sun, L Liuqingyue, M Yang, J Meng, S Ma, Y Kang, L Yu, Q Peng, Y Wei, W Zhang, R Sun, A Yeung, W Wan, K Sin, K Lee, M Wijanti, U Widodo, H Samsirun, T Sugiman, C Wisudarti, T Maskoen, N Hata, Y Kobe, O Nishida, D Miyazaki, S Nunomiya, S Uchino, N Kitamura, K Yamashita, S Hashimoto, H Fukushima, N Nik Adib, L Tai, B Tony, R Bigornia, J Palo, S Chatterjee, B Tan, A Kong, S Goh, C Lee, C Pothirat, B Khwannimit, P Theerawit, P Pornsuriyasak, A Piriyapatsom, A Mukhtar, A Nabil Hamdy, H Hosny, A Ashraf, M Mokhtari, S Nowruzinia, A Lotfi, F Zand, R Nikandish, O Moradi Moghaddam, J Cohen, O Sold, T Sfeir, A Hasan, D Abugaber, H Ahmad, T Tantawy, S Baharoom, H Algethamy, A Amr, G Almekhlafi, R Coskun, M Sungur, A Cosar, B Güçyetmez, O Demirkiran, E Senturk, H Ulusoy, H Atalan, S Serin, I Kati, Z Alnassrawi, A Almemari, K Krishnareddy, S Kashef, A Alsabbah, G Poirier, J Marshall, M Herridge, R Fernandez-Medero, G Fulda, S Banschbach, J Quintero, E Schroeder, C Sicoutris, R Gueret, R Kashyap, P Bauer, R Nanchal, R Wunderink, E Jimenez, A Ryan, D Prince, J Edington, F Van Haren, A Bersten, D J Hawkins, M Kilminster, D Sturgess, M Ziegenfuss, S O' Connor, J Lipman, L Campbell, R Mcallister, B Roberts, P Williams, R Parke, P Seigne, R Freebairn, D Nistor, C Oxley, P Young, R Valentini, N Wainsztein, P Comignani, M Casaretto, G Sutton, P Villegas, C Galletti, J Neira, D Rovira, J Hidalgo, F Sandi, E Caser, M Thompson, M D'agostino Dias, L Fontes, M Lunardi, N Youssef, S Lobo, R Silva, J Sales Jr, L Madeira Campos Melo, M Oliveira, M Fonte, C Grion, C Feijo, V Rezende, M Assuncao, A Neves, P Gusman, D Dalcomune, C Teixeira, K Kaefer, I Maia, V Souza Dantas, R Costa Filho, F Amorim, M Assef, P Schiavetto, J Houly, F Bianchi, F Dias, C Avila, J Gomez, L Rego, P Castro, J Passos, C Mendes, G Colozza Mecatti, M Ferrreira, V Irineu, M Guerreiro, S Ugarte, V Tomicic, C Godoy, W Samaniego, I Escamilla, L Castro Castro, G Libreros Duque, D Diaz-Guio, F Benítez, A Guerra Urrego, R Buitrago, G Ortiz, M Villalba Gaviria, D Salas, J Ramirez-Arce, E Salgado, D Morocho, J Vergara, M Chung Sang, C Orellana-Jimenez, L Garrido, O Diaz, D Resiere, C Osorio, A De La Vega, R Carrillo, V Sanchez, A Villagomez, R Martinez Zubieta, M Sandia, M Zalatiel, M Poblano, D Rodriguez Gonzalez, F Arrazola, L Juan Francisco, S A Ñamendys-Silva, M Hernandez, D Rodriguez Cadena, I Lopez Islas, C Ballesteros Zarzavilla, A Matos, I Oyanguren, J Cerna, R Quispe Sierra, R Jimenez, L Castillo, R Ocal, A Sencan, S Mareque Gianoni, A Deicas, J Hurtado, G Burghi, A Martinelli, I Von Der Osten, C Du Maine, M Bhattacharyya, S Bandyopadhyay, S Yanamala, P Gopal, S Sahu, M Ibrahim, D Rathod, N Mukundan, A Dewan, P Amin, S Samavedam, B Shah, D Gurupal, B Lahkar, A Mandal, M Sircar, S Ghosh, V Balasubramani, F Kapadia, S Vadi, K Nair, S Tripathy, S Nandakumar, J Sharma, A Kar, S Jha, K Zirpe-Gurav, M Patel, A Bhavsar, D Samaddar, A Kulkarni, M Hashmi, W Ali, S Nadeem, K Indraratna, A Margarit, P Urbanek, J Schlieber, J Reisinger, J Auer, A Hartjes, A Lerche, T Janous, E Kink, W Krahulec, K Smolle, M Van Der Schueren, P Thibo, M Vanhoof, I Ahmet, G Philippe, P Dufaye, O Jacobs, V Fraipont, P Biston, A Dive, Y Bouckaert, E Gilbert, B Gressens, E Pinck, V Collin, J L Vincent, J De Waele, R Rimachi, D Gusu, K De Decker, K Mandianga, L Heytens, X Wittebole, S Herbert, V Olivier, W Vandenheede, P Rogiers, P Kolodzeike, M Kruse, T Andersen, V Harjola, K Saarinen, M Leone, A Durocher, S Moulront, A Lepape, M Losser, P Cabaret, E Kalaitzis, E Zogheib, P Charve, B Francois, J Y Lefrant, B Beilouny, X Forceville, B Misset, F Jacobs, F Bernard, D Payen, A Wynckel, V Castelain, A Faure, P Lavagne, L Thierry, M Moussa, A Vieillard-Baron, M Durand, M Gainnier, C Ichai, S Arens, C Hoffmann, M Kaffarnik, C Scharnofske, I Voigt, C Peckelsen, M Weber, J Gille, A Lange, G Schoser, A Sablotzki, U Jaschinski, A Bluethgen, F Vogel, A Tscheu, T Fuchs, M Wattenberg, T Helmes, S Scieszka, M Heintz, S Sakka, J Kohler, F Fiedler, M Danz, Y Sakr, R Riessen, T Kerz, A Kersten, F Tacke, G Marx, T Volkert, A Schmutz, A Nierhaus, S Kluge, P Abel, R Janosi, S Utzolino, H Bracht, S Toussaint, M Giannakou Peftoulidou, P Myrianthefs, A Armaganidis, C Routsi, A Xini, E Mouloudi, I Kokoris, G Kyriazopoulos, S Vlachos, A Lavrentieva, P Partala, G Nakos, A Moller, S Stefansson, J Barry, R O'Leary, C Motherway, M Faheem, E Dunne, M Donnelly, T Konrad, E Bonora, C Achilli, S Rossi, G Castiglione, A Peris, D Albanese, N Stocchetti, G Citerio, L Mozzoni, E Sisillo, P De Negri, M Savioli, P Vecchiarelli, F Puflea, V Stankovic, G Minoja, S Montibeller, P Calligaro, R Sorrentino, M Feri, M Zambon, E Colombaroli, A Giarratano, T Pellis, C Capra, M Antonelli, A Gullo, C Chelazzi, A De Capraris, N Patroniti, M Girardis, F Franchi, G Berlot, M Buttigieg, H Ponssen, J Ten Cate, L Bormans, S Husada, M Buise, B Van Der Hoven, A Reidinga, M Kuiper, P Pickkers, G Kluge, S Den Boer, J Kesecioglu, H Van Leeuwen, H Flaatten, S Mo, V Branco, F Rua, E Lafuente, M Sousa, N Catorze, M Barros, L Pereira, A Vintém De Oliveira, J Gomes, I Gaspar, M Pereira, M Cymbron, A Dias, E Almeida, S Beirao, I Serra, R Ribeiro, P Povoa, F Faria, Z Costa-E-Silva, J Nóbrega, F Fernandes, J Gabriel, G Voga, E Rupnik, L Kosec, M Kerin Povšic, I Osojnik, V Tomic, A Sinkovic, J González, E Zavala, J Pérez Valenzuela, L Marina, P Vidal-Cortés, P Posada, A Ignacio Martin-Loeches, N Muñoz Guillén, M Palomar, J Sole-Violan, A Torres, M Gonzalez Gallego, G Aguilar, R Montoiro Alluév, M Argüeso, M Parejo, M Palomo Navarro, A Jose, N Nin, F Alvarez Lerma, O Martinez, E Tenza Lozano, S Arenal López, M Perez Granda, S Moreno, C Llubia, C De La Fuente Martos, P Gonzalez-Arenas, N Llamas Fernández, B Gil Rueda, I Estruch Pons, N Cruza, F Maroto, A Estella, A Ferrer, L Iglesias Fraile, B Quindos, A Quintano, M Tebar, P Cardinal, A Reyes, A Rodríguez, A Abella, S García Del Valle, S Yus, E Maseda, J Berezo, A Tejero Pedregosa, C Laplaza, R Ferrer, J Rico-Feijoo, M Rodríguez, P Monedero, K Eriksson, D Lind, D Chabanel, H Zender, K Heer, B Frankenberger, S Jakob, A Haller, S Mathew, R Downes, C Barrera Groba, A Johnston, R Meacher, R Keays, P Haji-Michael, C Tyler, A Ferguson, S Jones, D Tyl, A Ball, J Vogel, M Booth, P Downie, M Watters, S Brett, M Garfield, L Everett, S Heenen, S Dhir, Z Beardow, M Mostert, S Brosnan, N Pinto, S Harris, A Summors, N Andrew, A Rose, R Appelboam, O Davies, E Vickers, B Agarwal, T Szakmany, S Wimbush, I Welters, R Pearse, R Hollands, J Kirk-Bayley, N Fletcher, B Bray, D Brealey, Sakr, Y, Rubatto Birri, P, Kotfis, K, Nanchal, R, Shah, B, Kluge, S, Schroeder, M, Marshall, J, Vincent, J, Citerio, G, Sakr Y., Rubatto Birri P.N., Kotfis K., Nanchal R., Shah B., Kluge S., Schroeder M.E., Marshall J.C., and Vincent J.-L, E Tomas, E Amisi Bibonge, B Charra, M Faroudy, L Doedens, Z Farina, D Adler, C Balkema, A Kok, S Alaya, H Gharsallah, D Muzha, A Temelkov, G Georgiev, G Simeonov, G Tsaryanski, S Georgiev, A Seliman, S Vrankovic, Z Vucicevic, I Gornik, B Barsic, I Husedzinovic, P Pavlik, J Manak, E Kieslichova, R Turek, M Fischer, R Valkova, L Dadak, P Dostal, J Malaska, R Hajek, A Židková, P Lavicka, J Starkopf, Z Kheladze, M Chkhaidze, V Kaloiani, L Medve, A Sarkany, I Kremer, Z Marjanek, P Tamasi, I Krupnova, I Vanags, V Liguts, V Pilvinis, S Vosylius, G Kekstas, M Balciunas, J Kolbusz, A Kübler, B Mielczarek, M Mikaszewska-Sokolewicz, K Kotfis, B Tamowicz, W Sulkowski, P Smuszkiewicz, A Pihowicz, E Trejnowska, N Hagau, D Filipescu, G Droc, M Lupu, A Nica, R Stoica, D Tomescu, D Constantinescu, G Valcoreanu Zbaganu, A Slavcovici, V Bagin, D Belsky, S Palyutin, S Shlyapnikov, D Bikkulova, A Gritsan, G Natalia, E Makarenko, V Kokhno, A Tolkach, E Kokarev, B Belotserkovskiy, K Zolotukhin, V Kulabukhov, L Soskic, I Palibrk, R Jankovic, B Jovanovic, M Pandurovic, V Bumbasirevic, B Uljarevic, M Surbatovic, N Ladjevic, G Slobodianiuk, V Sobona, A Cikova, A Gebhardtova, C Jun, S Yunbo, J Dong, S Feng, M Duan, Y Xu, X Xue, T Gao, X Xing, X Zhao, C Li, G Gengxihua, H Tan, J Xu, L Jiang, Q Tiehe, Q Bingyu, Q Shi, Z Lv, L Zhang, L Jingtao, Z Zhen, Z Wang, T Wang, L Yuhong, Q Zhai, Y Chen, C Wang, W Jiang, W Ruilan, Y Chenv, H Xiaobo, H Ge, T Yan, C Yuhui, J Zhang, F Jian-Hong, H Zhu, F Huo, Y Wang, C Li, M Zhuang, Z Ma, J Sun, L Liuqingyue, M Yang, J Meng, S Ma, Y Kang, L Yu, Q Peng, Y Wei, W Zhang, R Sun, A Yeung, W Wan, K Sin, K Lee, M Wijanti, U Widodo, H Samsirun, T Sugiman, C Wisudarti, T Maskoen, N Hata, Y Kobe, O Nishida, D Miyazaki, S Nunomiya, S Uchino, N Kitamura, K Yamashita, S Hashimoto, H Fukushima, N Nik Adib, L Tai, B Tony, R Bigornia, R Bigornia, R Bigornia, J Palo, S Chatterjee, B Tan, A Kong, S Goh, C Lee, C Pothirat, B Khwannimit, P Theerawit, P Pornsuriyasak, A Piriyapatsom, A Mukhtar, A Nabil Hamdy, H Hosny, A Ashraf, M Mokhtari, S Nowruzinia, A Lotfi, F Zand, R Nikandish, O Moradi Moghaddam, J Cohen, O Sold, T Sfeir, A Hasan, D Abugaber, H Ahmad, T Tantawy, S Baharoom, H Algethamy, A Amr, G Almekhlafi, R Coskun, M Sungur, A Cosar, B Güçyetmez, O Demirkiran, E Senturk, H Ulusoy, H Atalan, S Serin, I Kati, Z Alnassrawi, A Almemari, K Krishnareddy, S Kashef, A Alsabbah, G Poirier, J Marshall, M Herridge, M Herridge, R Fernandez-Medero, G Fulda, S Banschbach, J Quintero, E Schroeder, C Sicoutris, R Gueret, R Kashyap, P Bauer, R Nanchal, R Wunderink, E Jimenez, A Ryan, D Prince, J Edington, F Van Haren, A Bersten, D J Hawkins, M Kilminster, D Sturgess, M Ziegenfuss, S O' Connor, J Lipman, L Campbell, R Mcallister, B Roberts, P Williams, R Parke, P Seigne, R Freebairn, D Nistor, C Oxley, P Young, R Valentini, N Wainsztein, P Comignani, M Casaretto, G Sutton, P Villegas, C Galletti, J Neira, D Rovira, J Hidalgo, F Sandi, E Caser, M Thompson, M D'agostino Dias, L Fontes, M Lunardi, N Youssef, S Lobo, R Silva, J Sales Jr, L Madeira Campos Melo, M Oliveira, M Fonte, C Grion, C Feijo, V Rezende, M Assuncao, A Neves, P Gusman, D Dalcomune, C Teixeira, K Kaefer, I Maia, V Souza Dantas, R Costa Filho, F Amorim, M Assef, P Schiavetto, J Houly, F Bianchi, F Dias, C Avila, J Gomez, L Rego, P Castro, J Passos, C Mendes, C Grion, G Colozza Mecatti, M Ferrreira, V Irineu, M Guerreiro, S Ugarte, V Tomicic, C Godoy, W Samaniego, I Escamilla, L Castro Castro, G Libreros Duque, D Diaz-Guio, F Benítez, A Guerra Urrego, R Buitrago, G Ortiz, M Villalba Gaviria, D Salas, J Ramirez-Arce, E Salgado, D Morocho, J Vergara, M Chung Sang, C Orellana-Jimenez, L Garrido, O Diaz, D Resiere, C Osorio, A De La Vega, R Carrillo, V Sanchez, A Villagomez, R Martinez Zubieta, M Sandia, M Zalatiel, M Poblano, D Rodriguez Gonzalez, F Arrazola, L Juan Francisco, S A Ñamendys-Silva, M Hernandez, D Rodriguez Cadena, I Lopez Islas, C Ballesteros Zarzavilla, A Matos, I Oyanguren, J Cerna, R Quispe Sierra, R Jimenez, L Castillo, R Ocal, A Sencan, S Mareque Gianoni, A Deicas, J Hurtado, G Burghi, A Martinelli, I Von Der Osten, C Du Maine, M Bhattacharyya, S Bandyopadhyay, S Yanamala, P Gopal, S Sahu, M Ibrahim, D Rathod, N Mukundan, A Dewan, P Amin, S Samavedam, B Shah, D Gurupal, B Lahkar, A Mandal, M Sircar, S Ghosh, V Balasubramani, F Kapadia, S Vadi, K Nair, S Tripathy, S Nandakumar, J Sharma, A Kar, S Jha, K Zirpe-Gurav, M Patel, A Bhavsar, D Samaddar, A Kulkarni, M Hashmi, W Ali, S Nadeem, K Indraratna, A Margarit, P Urbanek, J Schlieber, J Reisinger, J Auer, A Hartjes, A Lerche, T Janous, E Kink, W Krahulec, K Smolle, M Van Der Schueren, P Thibo, M Vanhoof, I Ahmet, G Philippe, P Dufaye, O Jacobs, V Fraipont, P Biston, A Dive, Y Bouckaert, E Gilbert, B Gressens, E Pinck, V Collin, J L Vincent, J De Waele, R Rimachi, D Gusu, K De Decker, K Mandianga, L Heytens, X Wittebole, S Herbert, V Olivier, W Vandenheede, P Rogiers, P Kolodzeike, M Kruse, T Andersen, V Harjola, K Saarinen, M Leone, A Durocher, S Moulront, A Lepape, M Losser, P Cabaret, E Kalaitzis, E Zogheib, P Charve, B Francois, J Y Lefrant, B Beilouny, X Forceville, B Misset, F Jacobs, F Bernard, D Payen, A Wynckel, V Castelain, A Faure, P Lavagne, L Thierry, M Moussa, A Vieillard-Baron, M Durand, M Gainnier, C Ichai, S Arens, C Hoffmann, M Kaffarnik, C Scharnofske, I Voigt, C Peckelsen, M Weber, J Gille, A Lange, G Schoser, A Sablotzki, U Jaschinski, A Bluethgen, F Vogel, A Tscheu, T Fuchs, M Wattenberg, T Helmes, S Scieszka, M Heintz, S Sakka, J Kohler, F Fiedler, M Danz, Y Sakr, R Riessen, T Kerz, A Kersten, F Tacke, G Marx, T Volkert, A Schmutz, A Nierhaus, S Kluge, P Abel, R Janosi, S Utzolino, H Bracht, S Toussaint, M Giannakou Peftoulidou, P Myrianthefs, A Armaganidis, C Routsi, A Xini, E Mouloudi, I Kokoris, G Kyriazopoulos, S Vlachos, A Lavrentieva, P Partala, G Nakos, A Moller, S Stefansson, J Barry, R O'Leary, C Motherway, M Faheem, E Dunne, M Donnelly, T Konrad, E Bonora, C Achilli, S Rossi, G Castiglione, A Peris, D Albanese, N Stocchetti, G Citerio, L Mozzoni, E Sisillo, P De Negri, M Savioli, P Vecchiarelli, F Puflea, V Stankovic, G Minoja, S Montibeller, P Calligaro, R Sorrentino, M Feri, M Zambon, E Colombaroli, A Giarratano, T Pellis, C Capra, M Antonelli, A Gullo, C Chelazzi, A De Capraris, N Patroniti, M Girardis, F Franchi, G Berlot, M Buttigieg, H Ponssen, J Ten Cate, L Bormans, S Husada, M Buise, B Van Der Hoven, A Reidinga, M Kuiper, P Pickkers, G Kluge, S Den Boer, J Kesecioglu, H Van Leeuwen, H Flaatten, S Mo, V Branco, F Rua, E Lafuente, M Sousa, N Catorze, M Barros, L Pereira, A Vintém De Oliveira, J Gomes, I Gaspar, M Pereira, M Cymbron, A Dias, E Almeida, S Beirao, I Serra, R Ribeiro, P Povoa, F Faria, Z Costa-E-Silva, J Nóbrega, F Fernandes, J Gabriel, G Voga, E Rupnik, L Kosec, M Kerin Povšic, I Osojnik, V Tomic, A Sinkovic, J González, E Zavala, J Pérez Valenzuela, L Marina, P Vidal-Cortés, P Posada, A Ignacio Martin-Loeches, N Muñoz Guillén, M Palomar, J Sole-Violan, A Torres, M Gonzalez Gallego, G Aguilar, R Montoiro Alluév, M Argüeso, M Parejo, M Palomo Navarro, A Jose, N Nin, F Alvarez Lerma, O Martinez, E Tenza Lozano, S Arenal López, M Perez Granda, S Moreno, C Llubia, C De La Fuente Martos, P Gonzalez-Arenas, N Llamas Fernández, B Gil Rueda, I Estruch Pons, N Cruza, F Maroto, A Estella, A Ferrer, L Iglesias Fraile, B Quindos, A Quintano, M Tebar, P Cardinal, A Reyes, A Rodríguez, A Abella, S García Del Valle, S Yus, E Maseda, J Berezo, A Tejero Pedregosa, C Laplaza, R Ferrer, J Rico-Feijoo, M Rodríguez, P Monedero, K Eriksson, D Lind, D Chabanel, H Zender, K Heer, B Frankenberger, S Jakob, A Haller, S Mathew, R Downes, C Barrera Groba, A Johnston, R Meacher, R Keays, P Haji-Michael, C Tyler, A Ferguson, S Jones, D Tyl, A Ball, J Vogel, M Booth, P Downie, M Watters, S Brett, M Garfield, L Everett, S Heenen, S Dhir, Z Beardow, M Mostert, S Brosnan, N Pinto, S Harris, A Summors, N Andrew, A Rose, R Appelboam, O Davies, E Vickers, B Agarwal, T Szakmany, S Wimbush, I Welters, R Pearse, R Hollands, J Kirk-Bayley, N Fletcher, B Bray, D Brealey

Subjects
Internationality, Time Factors, Databases, Factual, medicine.medical_treatment, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Settore MED/41 - Anestesiologia, Critical Care and Intensive Care Medicine, law.invention, 0302 clinical medicine, law, Risk Factors, 80 and over, 030212 general & internal medicine, Hospital Mortality, 610 Medicine & health, Aged, 80 and over, Medical Audit, fluid output, Middle Aged, Water-Electrolyte Balance, fluid administration, Intensive care unit, outcome, septic shock, Adult, Aged, Humans, Intensive Care Units, Sepsis, Fluid Therapy, Cohort, Human, Cohort study, medicine.medical_specialty, Time Factor, Sepsi, Intensive Care Unit, Observational Study, 03 medical and health sciences, Databases, Hemofiltration, medicine, Journal Article, Risk factor, Intensive care medicine, Factual, Hetastarch, business.industry, Septic shock, Risk Factor, 030208 emergency & critical care medicine, fluid administration, fluid output, outcome, septic shock, medicine.disease, business
Abstract

Contains fulltext : 177598.pdf (Publisher’s version ) (Closed access) OBJECTIVES: Excessive fluid therapy in patients with sepsis may be associated with risks that outweigh any benefit. We investigated the possible influence of early fluid balance on outcome in a large international database of ICU patients with sepsis. DESIGN: Observational cohort study. SETTING: Seven hundred and thirty ICUs in 84 countries. PATIENTS: All adult patients admitted between May 8 and May 18, 2012, except admissions for routine postoperative surveillance. For this analysis, we included only the 1,808 patients with an admission diagnosis of sepsis. Patients were stratified according to quartiles of cumulative fluid balance 24 hours and 3 days after ICU admission. MEASUREMENTS AND MAIN RESULTS: ICU and hospital mortality rates were 27.6% and 37.3%, respectively. The cumulative fluid balance increased from 1,217 mL (-90 to 2,783 mL) in the first 24 hours after ICU admission to 1,794 mL (-951 to 5,108 mL) on day 3 and decreased thereafter. The cumulative fluid intake was similar in survivors and nonsurvivors, but fluid balance was less positive in survivors because of higher fluid output in these patients. Fluid balances became negative after the third ICU day in survivors but remained positive in nonsurvivors. After adjustment for possible confounders in multivariable analysis, the 24-hour cumulative fluid balance was not associated with an increased hazard of 28-day in-hospital death. However, there was a stepwise increase in the hazard of death with higher quartiles of 3-day cumulative fluid balance in the whole population and after stratification according to the presence of septic shock. CONCLUSIONS: In this large cohort of patients with sepsis, higher cumulative fluid balance at day 3 but not in the first 24 hours after ICU admission was independently associated with an increase in the hazard of death.

Published
2017
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11. A primer for the gastroenterology provider on psychosocial assessment of patients with disorders of gut-brain interaction.

Author

Ballou S, Vasant DH, Guadagnoli L, Reed B, Chiarioni G, Ten Cate L, Keefer L, and Kinsinger SW

Subjects
Humans, Gastrointestinal Diseases psychology, Gastrointestinal Diseases diagnosis, Gastroenterology methods, Quality of Life, Brain-Gut Axis physiology
Abstract

Background: GI-specific psychological factors are important contributors to patients' symptom experience and quality of life across all disorders of gut-brain interaction (DGBI). Clinicians' ability to recognize the role of these psychological factors is essential for formulating a biopsychosocial case conceptualization and informing treatment decisions., Purpose: This article will familiarize gastroenterology providers with conceptualizing the role of GI-specific psychological factors in DGBI and provides stepwise, practical guidance for how to assess these during clinical encounters in a time-efficient manner., (© 2024 John Wiley & Sons Ltd.)

Published
2024
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12. The inability to belch syndrome: A study using concurrent high-resolution manometry and impedance monitoring.

Author

Oude Nijhuis RAB, Snelleman JA, Oors JM, Kessing BF, Heuveling DA, Schuitenmaker JM, Ten Cate L, Smout AJPM, and Bredenoord AJ

Subjects
Adolescent, Adult, Electric Impedance, Eructation, Esophageal Sphincter, Upper, Humans, Male, Manometry methods, Young Adult, Botulinum Toxins, Type A, Esophagitis, Peptic, Gastroesophageal Reflux diagnosis, Gastroesophageal Reflux drug therapy
Abstract

Introduction: Although inability to belch has previously been linked to dysfunction of the upper esophageal sphincter (UES), its underlying pathogenesis remains unclear. Our aim was to study mechanisms underlying inability to belch and the effect of UES botulinum toxin (botox) injections in these patients., Methods: We prospectively enrolled consecutive patients with symptoms of inability to belch. Patients underwent stationary high-resolution impedance manometry (HRIM) with belch provocation and ambulatory 24-h pH-impedance monitoring before and 3 months after UES botox injection., Results: Eight patients (four males, age 18-37 years) were included. Complete and normal UES relaxation occurred in response to deglutition in all patients. A median number of 33(15-64) gastroesophageal gas reflux episodes were observed. Despite the subsequent increase in esophageal pressure (from -4.0 [-7.7-4.2] to 8 [3.3-16.1] mmHg; p < 0.012), none of the gastroesophageal gas reflux events resulted in UES relaxation. Periods of continuous high impedance levels, indicating air entrapment (median air presence time 10.5% [0-43]), were observed during 24-h impedance monitoring. UES botox reduced UES basal pressure (from 95.7[41.2-154.0] to 29.2 [16.7-45.6] mmHg; p < 0.02) and restored belching capacity in all patients. As a result, esophageal air presence time decreased from 10.5% (0-43.4) to 0.7% (0.1-18.6; p < 0.02) and esophageal symptoms improved in all patients (VAS 6.0 [1.0-7.9] to 1.0 [0.0-2.5]; p < 0.012)., Conclusion: The results of this study underpin the existence of a syndrome characterized by an inability to belch and support the hypothesis that ineffective UES relaxation, with subsequent esophageal air entrapment, may lead to esophageal symptoms., (© 2021 The Authors. Neurogastroenterology & Motility published by John Wiley & Sons Ltd.)

Published
2022
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13. Speech Therapy as Treatment for Supragastric Belching.

Author

Ten Cate L, Herregods TVK, Dejonckere PH, Hemmink GJM, Smout AJPM, and Bredenoord AJ

Subjects
Esophagus, Female, Humans, Male, Middle Aged, Pilot Projects, Retrospective Studies, Eructation therapy, Speech Therapy methods
Abstract

The purpose of this study was to describe a newly developed speech therapy program as an innovating therapeutic approach and to assess the results of this intervention in patients with supragastric belching. This is a retrospective analysis of prospectively gathered data from 73 patients with supragastric belching who were treated with speech therapy between 2007 and 2017. Of these, 48 were included for evaluation of therapy. Thirty patients had supragastric belching proven by 24-h impedance measurements. Eighteen patients were diagnosed by an experienced speech language pathologist as having supragastric belching according to precise criteria. Speech therapy consists of explanation, creating awareness of esophageal air influx and exercises to discontinue the supragastric belching mechanism. Therapy effect was measured by comparing visual analogue scale (VAS) scores on belching and related symptoms. The median symptom duration at the start of therapy was 2 years. Supragastric belching symptoms decreased significantly with a total median VAS score of 406 (291-463) prior to treatment and a median VAS score of 125 (17-197) following treatment. Forty patients (83%) had a sufficient to major result with a median therapy duration of 3 months and ten sessions. Speech therapy was an effective treatment in the majority of patients with supragastric belching.

Published
2018
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14. The effect of visual feedback and training in auditory-perceptual judgment of voice quality.

Author

Barsties B, Beers M, Ten Cate L, Van Ballegooijen K, Braam L, De Groot M, Van Der Kant M, Kruitwagen C, and Maryn Y

Subjects
Acoustic Stimulation, Adolescent, Adult, Aged, Aged, 80 and over, Child, Female, Humans, Male, Middle Aged, Observer Variation, Phonation, Photic Stimulation, Prospective Studies, Reproducibility of Results, Severity of Illness Index, Speech Production Measurement, Voice Disorders physiopathology, Young Adult, Feedback, Sensory, Formative Feedback, Judgment, Speech Acoustics, Speech Perception, Speech-Language Pathology methods, Visual Perception, Voice Disorders diagnosis, Voice Quality
Abstract

The aim of the present investigation was to evaluate the effect of visual feedback on rating voice quality severity level and the reliability of voice quality judgment by inexperienced listeners. For this purpose two training programs were created, each lasting 2 hours. In total 37 undergraduate speech-language therapy students participated in the study and were divided into a visual plus auditory-perceptual feedback group (V + AF), an auditory-perceptual feedback group (AF), and a control group with no feedback (NF). All listeners completed two rating sessions judging overall severity labeled as grade (G), roughness (R), and breathiness (B). The judged voice samples contained the concatenation of continuous speech and sustained phonation. No significant rater reliability changes were found in the pre- and posttest between the three groups in every GRB-parameter (all p > 0.05). There was a training effect seen in the significant improvement of rater reliability for roughness within the NF and AF groups (all p < 0.05), and for breathiness within the V + AF group (p < 0.01). The rating of the severity level of roughness changed significantly after the training in the AF and V + AF groups (p < 0.01), and the breathiness severity level changed significantly after the training in the V + AF group (p < 0.01). The training of V + AF and AF may only minimally influence the reliability in the judgment of voice quality but showed significant influence on rating the severity level of GRB parameters. Therefore, the use of both visual and auditory anchors while rating as well as longer training sessions may be required to draw a firm conclusion.

Published
2017
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15. Outcome of Endometrial Cancer Stage IIIA with Adnexa or Serosal Involvement Only.

Author

Jobsen JJ, Naudin Ten Cate L, Lybeert ML, Scholten A, van der Steen-Banasik EM, van der Palen J, Stenfert Kroese MC, Slot A, Schutter EM, and Siesling S

Abstract

Objective. The aim of this study is to look at possible differences in outcome between serosa and adnexal involvement stage IIIA endometrial carcinoma. Methods. 67 patients with stage IIIA endometrial carcinoma were included, 46 with adnexal involvement and 21 with serosa. A central histopathological review was performed. Results. The 7-year locoregional failure rate was (LRFR) 2.2% for adnexal involvement and 16.0% for involvement of the serosa (P = .0522). The 7-year distant metastasis-free survival was 72.7% for adnexal involvement and 58.7% for serosa (P = .3994). The 7-year disease-specific survival (DSS) was 71.8% for patients with adnexal involvement and 75.4% for patients with serosa. Conclusion. Endometrial carcinoma stage IIIA with involvement of the adnexa or serosa showed to have a comparable disease-specific survival. Locoregional control was worse for serosa involvement compared to adnexa.

Published
2011
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16. Villoglandular papillary adenocarcinoma of the cervix. Beware of a wolf in sheep's clothing.

Author

Bouman A, Oosterhuis GJ, Naudin ten Cate L, and van Doorn GA

Subjects
Adult, Female, Humans, Adenocarcinoma, Papillary pathology, Uterine Cervical Neoplasms pathology
Abstract

Villoglandular papillary adenocarcinoma of the cervix is a well differentiated form of cervical adenocarcinoma with a favourable prognosis and a conservative procedure is suggested. We present three cases of villoglandular papillary adenocarcinoma of the cervix. Histological examination of a biopsy of each cervix showed well differentiated villoglandular papillary adenocarcinoma, stage Ib according to FIGO classification. In all cases the disease was limited to the cervix. Nevertheless, histopathological examination of the surgical specimen revealed an infiltrating component with squamous differentiation in one case, while in a second case histopathological examination revealed a moderately differentiated papillary adenocarcinoma with a superficially infiltrating growth-pattern besides the villoglandular papillary adenocarcinoma. Before conservative therapy is considered, careful evaluation of the presence of poor prognostic features must be made. One should consider whether conservative therapy is sufficient because of the predominance of concomitance of other carcinoma besides the villoglandular papillary adenocarcinoma.

Published
1999
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17. Intracranial teratoma with multiple fetuses: pre- and post-natal appearance.

Author

Naudin ten Cate L, Vermeij-Keers C, Smit DA, Cohen-Overbeek TE, Gerssen-Schoorl KB, and Dijkhuizen T

Subjects
Abnormalities, Multiple pathology, Female, Fetal Death, Humans, Infant, Newborn, Prenatal Diagnosis, Brain Neoplasms complications, Brain Neoplasms pathology, Fetus abnormalities, Teratoma complications, Teratoma pathology
Abstract

An intracranial teratoma in which six distinct dysmorphic fetuses were included was studied at autopsy. Karyotopic studies showed a normal chromosomal number in the child and the same karyotype in the three tumoral parts were examined. This is the second tumor of this type reported.

Published
1995
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18. Unusual haemostasis for an unusual tumour. Catastrophic bleeding from a tactile neurofibroma affecting the thoracic vertebrae. Case report.

Author

Vincent JG, Naudin ten Cate L, Kaan GL, van Horn JR, and Pruszczynski M

Subjects
Aortic Dissection diagnosis, Aorta, Thoracic, Aortic Aneurysm diagnosis, Diagnosis, Differential, Female, Hemorrhage diagnosis, Hemorrhage surgery, Humans, Middle Aged, Neurofibroma pathology, Spinal Neoplasms pathology, Hemorrhage etiology, Neurofibroma complications, Spinal Neoplasms complications, Thoracic Vertebrae
Abstract

The symptomatology of a typical acute descending thoracic aorta dissection was imitated by profuse haemorrhage caused by a benign tumour composed almost exclusively of Wagner-Meissner like tactile corpuscles and fatty tissue. The tumour caused extensive destruction of the bodies of the fifth and sixth thoracic vertebrae at the level of the vertebro-costal articulation. Emergency cross clamping of the descending aorta and haemostasis of the bleeding from osteal defects by tamponade with bone polymethyl methacrylate appeared the only way to control the life threatening haemorrhage. It seems that an intrathoracic tactile neurofibroma with a similar case history has not been reported till now.

Published
1990

19. Ultrastructural and immunohistochemical study of epithelioid hemangioendothelioma of bone: coexpression of epithelial and endothelial markers.

Author

van Haelst UJ, Pruszczynski M, ten Cate LN, and Mravunac M

Subjects
Adult, Aged, Bone Neoplasms analysis, Cell Nucleus ultrastructure, Cytoplasm ultrastructure, Endothelium analysis, Epithelium analysis, Female, Humans, Immunohistochemistry, Keratins analysis, Lectins analysis, Male, Microscopy, Electron, Middle Aged, Vimentin analysis, von Willebrand Factor analysis, Biomarkers, Tumor analysis, Bone Neoplasms ultrastructure, Plant Lectins, Sarcoma, Ewing ultrastructure
Abstract

Four cases of epithelioid hemangioendothelioma of bone--a borderline malignant tumor of vascular origin--were studied ultrastructurally and immunohistochemically. The epithelioid tumor cells were positive for vimentin, polyclonal and monoclonal cytokeratins, and the endothelial markers factor VIII-related antigen (FVIII:RAg) and Ulex europaeus agglutinin I. The coexpression of polyclonal cytokeratin and FVIII:RAg was demonstrated by means of step sections in the same tumor cells. The endothelial origin of epithelioid tumor cells was supported ultrastructurally by identification of Weibel-Palade bodies.

Published
1990

20. Malignant epithelioid hemangioendothelioma at the site of a hip prosthesis.

Author

van der List JJ, van Horn JR, Slooff TJ, and ten Cate LN

Subjects
Aged, Bone Neoplasms diagnostic imaging, Bone Neoplasms pathology, Female, Hemangioendothelioma diagnostic imaging, Hemangioendothelioma pathology, Humans, Radiography, Acetabulum, Bone Neoplasms etiology, Hemangioendothelioma etiology, Hip Prosthesis adverse effects
Abstract

We report a case of malignant epithelioid hemangioendothelioma in the acetabulum and ipsilateral femur 11 years after a total hip prosthesis.

Published
1988
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21. Benign cystic ovarian teratoma with lung differentiation.

Author

Pruszczyński M, Sporny S, ten Cate LN, and Smedts F

Subjects
Female, Humans, Middle Aged, Choristoma pathology, Lung, Ovarian Neoplasms pathology, Teratoma pathology
Abstract

Organoid development of the lung in ovarian teratoma is very rare. The fifth case of this kind with an adult type lung and a bronchiolar system is presented in this paper. The largest published series of benign cystic ovarian teratoma are analysed. Factors influencing the incidence of endodermally drived tissues are discussed.

Published
1988

22. Immunohistochemical and ultrastructural studies of a primary aortic intimal sarcoma.

Author

Pruszczynski M, Coronel CM, Naudin ten Cate L, Roholl PJ, and van der Kley AJ

Subjects
Female, Humans, Immunohistochemistry, Middle Aged, Aorta, Abdominal metabolism, Aorta, Abdominal ultrastructure, Sarcoma metabolism, Sarcoma ultrastructure
Abstract

An intimal sarcoma of the abdominal aorta in a 63-year-old woman is reported. The clinical symptoms consisted of chronic arterial hypertension, vomiting and epigastric pain. Treatment was operative, but the patient died 20 hours after surgery. The studies were performed on a surgical specimen and on autopsy material. The aortic tumour consisted of pleomorphic spindle-shaped and giant cells. In the vertebral metastases a storiform pattern of the tumour cells was found. No specific features characteristic for leiomyogenic, lipogenic or an endothelial nature of the tumour giant cells was disclosed in electron microscopy and the picture rather indicated their histiocytic character. Of the 18 cellular markers studied, the immunostainings for vimentin and alpha-1-antichymotrypsin were evidently positive. The tumour was classified as a pleomorphic intimal aortic sarcoma probably a malignant fibrous histiocytoma (MFH). The literature on 26 previously published aortal tumours is reviewed with emphasis on their topographical distribution and histological classification. In only 4 previous cases was the final diagnosis supported by electron microscopical or immunopathological findings. The role of marker studies in the classification of aortal tumours is discussed.

Published
1988
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