127 results on '"Tellers, David"'
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2. Computational Design and Experimental Characterization of Peptides Intended for pH-Dependent Membrane Insertion and Pore Formation
3. CHEMGENIE: integration of chemogenomics data for applications in chemical biology
4. Identification of proximal biomarkers of PKC agonism and evaluation of their role in HIV reactivation
5. Approaches to Eradicate HIV Infection
6. The PET tracer [ 11 C]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer’s disease
7. Development of ProTx-II Analogues as Highly Selective Peptide Blockers of Nav1.7 for the Treatment of Pain
8. Guiding Chemically Synthesized Peptide Drug Lead Optimization by Derisking Mast Cell Degranulation-Related Toxicities of a NaV1.7 Peptide Inhibitor
9. Development of practical syntheses of potent non-nucleoside reverse transcriptase inhibitors
10. [1,2]-Aryl migration in the synthesis of substituted indoles: scope, mechanism, and high throughput experimentation
11. Current Status of Approaches to Eradicate HIV Infection
12. Discovery of [11C]MK-6884: a positron emission tomography (PET) imaging agent for the study of M4 muscarinic receptor positive allosteric modulators (PAMs) in neurodegenerative diseases
13. On the mechanism of an asymmetric [alpha],[beta]-unsaturated carboxylic acid hydrogenation: Application to the synthesis of a PG[D.sub.2] receptor antagonist
14. Discovery of an Anion-Dependent Farnesyltransferase Inhibitor from a Phenotypic Screen
15. Biocatalytic and chemocatalytic approaches to the highly stereoselective 1,2-reduction of an α,β-unsaturated ketone
16. Mechanistic study of ligand substitution processes in Tplr(III) complexes
17. Discovery of [11C]MK-6884: A Positron Emission Tomography (PET) Imaging Agent for the Study of M4Muscarinic Receptor Positive Allosteric Modulators (PAMs) in Neurodegenerative Diseases
18. Synthesis of iridium(III)carboxamides via the bimetallic reaction between Cp (super)* (PMe (sub)3)IrPh(OH) and [Cp (super)* (PMe (sub)3)Ir(Ph)NCR] (super)+
19. Guiding Chemically Synthesized Peptide Drug Lead Optimization by Derisking Mast Cell Degranulation-Related Toxicities of a NaV1.7 Peptide Inhibitor.
20. The PET tracer [11C]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer's disease.
21. Novel pH Selective, Highly Lytic Peptides Based on a Chimeric Influenza Hemagglutinin Peptide/Cell Penetrating Peptide Motif
22. Post-Synthetic Modification of Oligonucleotides via Orthogonal Amidation and Copper Catalyzed Cycloaddition Reactions
23. Electronic and medium effects on the rate of arene C-H bond activation by cationic Ir(lll) complexes
24. Development of a Kilogram-Scale Asymmetric Synthesis of a Potent DP Receptor Antagonist
25. Highly diastereoselective heterogeneously catalyzed hydrogenation of enamines for the synthesis of chiral beta-amino acid derivatives
26. Binding of chlorohydrocarbons to metal centers: quantitative evaluation of relative binding constants and structural characterization of the first isolable transition metal-chloromethane adduct
27. Synthesis of Chiralsec-Alcohols by Ketone Reduction
28. High-Throughput Chemical Modification of Oligonucleotides for Systematic Structure–Activity Relationship Evaluation
29. Practical Synthesis of A Macrocyclic HCV Protease Inhibitor: A High-Yielding Macrolactam Formation
30. Molecular Umbrella Conjugate for the Ocular Delivery of siRNA
31. C-H bond activation by a rare cationic iridium dinitrogen complex. An important electronic effect in the chemistry of the hydridotris(pyrazolyl)borate ligand
32. Development and Application of a User-Friendly Automated HPLC Dilution Macro for API Route Optimization
33. Correction to Synthesis of Vaniprevir (MK-7009): Lactamization To Prepare a 22-Membered Macrocycle
34. Synthesis of Vaniprevir (MK-7009): Lactamization To Prepare a 22-Membered Macrocycle
35. Rapid HATU-Mediated Solution Phase siRNA Conjugation
36. ChemInform Abstract: Enabling Asymmetric Hydrogenation for the Design of Efficient Synthesis of Drug Substances
37. Development of a Kilogram-Scale Asymmetric Synthesis of a Potent DP Receptor Antagonist
38. Enabling Asymmetric Hydrogenation for the Design of Efficient Synthesis of Drug Substances
39. ChemInform Abstract: [1,2]-Aryl Migration in the Synthesis of Substituted Indoles: Scope, Mechanism, and High Throughput Experimentation.
40. Development of a Sequential Tetrahydropyran and Tertiary Butyl Deprotection: High-Throughput Experimentation, Mechanistic Analysis, and DOE Optimization
41. Enantioselective Synthesis of 1,4-Dihydrobenzoxathiins via Sulfoxide-Directed Borane Reduction.
42. High-Throughput Chemical Modification of Oligonucleotidesfor Systematic Structure–Activity Relationship Evaluation.
43. On the Mechanism of an Asymmetric α,β-Unsaturated Carboxylic Acid Hydrogenation: Application to the Synthesis of a PGD2 Receptor Antagonist
44. Enantioselective Synthesis of 1,4-Dihydrobenzoxathiins via Sulfoxide-Directed Borane Reduction
45. Enantioselective hydrogenation of an α-alkoxy substituted ketone with chiral ruthenium (phosphinoferrocenyl)oxazoline complexes
46. Highly Diastereoselective Heterogeneously Catalyzed Hydrogenation of Enamines for the Synthesis of Chiral β-Amino Acid Derivatives.
47. Fundamentals of Molecular Catalysis. Current Methods in Inorganic Chemistry. Volume 3
48. A [2 + 2] Cycloaddition Route to Dimethylaminomethylene Vinamidinium Salts
49. Electronic and Medium Effects on the Rate of Arene C−H Bond Activation by Cationic Ir(III) Complexes
50. Binding of Chlorohydrocarbons to Metal Centers: Quantitative Evaluation of Relative Binding Constants and Structural Characterization of the First Isolable Transition Metal−Chloromethane Adduct
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