1. Treatment of Libman-Sacks endocarditis by combination of warfarin and immunosuppressive therapy.
- Author
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Sonsöz MR, Tekin RD, Gül A, Buğra Z, and Atılgan D
- Subjects
- Adult, Echocardiography, Transesophageal, Endocarditis diagnostic imaging, Female, Humans, Immunosuppressive Agents administration & dosage, Lupus Erythematosus, Systemic complications, Lupus Erythematosus, Systemic diagnostic imaging, Warfarin administration & dosage, Young Adult, Endocarditis drug therapy, Immunosuppressive Agents therapeutic use, Lupus Erythematosus, Systemic drug therapy, Warfarin therapeutic use
- Abstract
Antiphospholipid syndrome (APS) is a clinical disorder that creates an increased risk of arterial or venous thrombotic events or pregnancy-associated complications and includes the presence of autoantibodies against negatively charged phospholipids. This syndrome is often associated with systemic autoimmune diseases, such as systemic lupus erythematosus (SLE). Libman-Sacks endocarditis is a form of non-bacterial thrombotic endocarditis and is infrequently seen in APS. There are few data documenting the echocardiographic response of APS valve disease to medical treatment. This is an unusual case of a young female patient with SLE and APS who had chorea and non-bacterial thrombotic aortic valve endocarditis. Echocardiography revealed that the vegetation had receded after a combination of warfarin and immunosuppressive therapy.
- Published
- 2019
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