Search

bulunamadı.

In this work, seven copolymers possessing thienothiophene and mesitylboron units were prepared. Incorporation of triphenylamine (TPA) and tetraphenylethene (TPE) into TT unit was probed to enhance their light-emitting efficiencies. Density functional theory investigations of the model compounds revealed the presence of an intramolecular charge transfer transition between the donor TT units and the boron acceptor atom. Among the seven TT-boron copolymers, four of them were used for the fabrication of polymer light emitting diodes 9PLEDs) and two of the devices exhibited pure white color according to the CIE. Although the efficiencies of the devices are low, as this study is the first example of thienothiophene inverted perpendicular inverted perpendicular-boron copolymers emitting white color, they are promising examples for future studies.

Objective: In this experiment, supplementation of the diet with increased levels of glutamine was used to determine glutamine enriched diet effect on the healing of ileal anastomosis.Methods: Forty albino Wistar rats, in four groups, had a special diet 7 days prior to surgery and 7 days after surgery. On the 7th day of study a complete cut of the ileal wall was carried out and an anastomosis was performed using single layer interrupted inverting sutures. Group 1 received a normal diet for all 14 days; group 2 received a glutamine enriched diet 7 days prior to surgery and a normal diet 7 days after surgery; group 3 received a normal diet prior to surgery and a glutamine enriched diet after surgery; group 4 received a constant glutamine enriched diet. On the 7th postoperative day, tensile strength measurements and hydroxyproline level analyses were done.Results: A preoperative glutamine enriched diet did not show any significant improvement in the bursting pressure and hydroxyproline levels on the 7th postoperative day, but pre and postoperative, and postoperative glutamine enriched diet significantly improved when compared with the normal diet group (p

Two novel D-A (donor-acceptor) and one D-A-D small molecules containing mesitylborane as an acceptor and triphenylamine as a donor, linked through a thieno[3,2-b]thiophene p-conjugated spacer, are synthesized and characterized. Their photo- and electrochemical properties were investigated by experimental and computational studies. The emission quantum efficiencies were determined to be between 46% and 68% in THF. Their solid-state quantum yields were recorded up to 42%. The fabricated electroluminescent devices as emitting materials showed sky-blue to yellowish green emissions. Their devices exhibit high performance with a turn-on voltage, maximal brightness, and highest luminescence efficiency of up to 4.0 V, 1200 cd m(-2) and 1.13 cd A(-1), respectively. These results pave new avenues for the future molecules possessing D and A units connected via fused thiophenes.

Background: There is a lack of specificity of the analgesic agents used to treat headache and underlying acute carbon monoxide poisoning. Objective: To compare effectiveness of "oxygen alone" vs "metoclopramide plus oxygen" vs "metamizole plus oxygen" therapy in treating carbon monoxide-induced headache. Design: A prospective, multicenter, double-blind, controlled trial. Setting: Three emergency departments in Turkey. Population: Adult carbon monoxide poisoning patients with headache. Methods: A total of 117 carbon monoxide-intoxicated patients with headache were randomized into 3 groups and assessed at baseline, 30 minutes, 90 minutes, and 4 hours. Main Outcome Measure: The primary outcomewas patient-reported improvement rates for headache. Secondary end points included nausea, need for rescue medication during treatment, and reduction in carboxyhemoglobin levels. Results: During observation, there was no statistical difference between drug type and visual analog scale score change at 30 minutes, 90 minutes, or 4 hours, for either headache or nausea. No rescue medication was needed during the study period. The reduction in carboxyhemoglobin levels did not differ among the 3 groups. Conclusion: The use of "oxygen alone" is as efficacious as "oxygen plus metoclopramide" or "oxygen plus metamizole sodium" in the treatment of carbon monoxide-induced headache. (C) 2016 Elsevier Inc. All rights reserved.

We carried out united-atom molecular dynamics simulations to understand the structural properties of peptide amphiphile (PA)-based cylindrical nanofibers and the factors that play a role in the "Self-Assembly" process on some specific nanofibers. In our simulations, we start from various cylindrical nanofiber structures with a different number of layers and a different number of PAs in each layer, based on previous experimental and theoretical results. We find that the 19-layered nanofiber, with 12 PAs at each layer, distributed radially and uniformly with alkyl chains in the center, is the most stable configuration with a diameter of 8.4 nm which is consistent with experimental results. The most dominant secondary structures formed in the fibers are random coils and beta-sheets, respectively. We also find that hydrophobic interactions between the VVAG-VVAG moiety of the PA molecules and electrostatic interactions between D-Na+ and between E-R are responsible for the fiber's self-assembly properties. During the aggregation process, first dimers, then trimers are formed.

We report on an example of odd even effect in self-assembled peptide amphiphiles (PAs) forming a cylindrical nanofiber. Minimum energy of the nanofiber depends on whether there are odd or even number of layers and whether each layer has odd or even number of PAs. More specifically, minimum energy for a nanofiber built of odd number of layers is achieved if each layer has even number of PAs uniformly, and radially aligned with alkyl chains in the center. On the other hand if the number of layers is even, energy is minimized if each layer has an odd number of PAs. (C) 2014 Elsevier B.V. All rights reserved.

Risk and Reliability in Geotechnical Engineering

Purpose: To investigate the efficacy and safety of neoadjuvant chemotherapy with docetaxel plus epirubicin with granulocyte colony-stimulating factor (G-CSF) support in locally advanced breast cancer patients.

Seroma formation is the most common complication after mastectomy and continues to be an important problem during the early postoperative period. Several surgical and medical methods have been developed to try to overcome this problem; however, so far none have been used successfully in the routine clinical practice. The aim of this study is to evaluate the effects of Corynebacterium parvum (CP) as a sclerosing agent in both prevention and treatment of seromas after mastectomy and axillary dissection in an animal model. Sixty female Sprague-Dawley rats underwent mastectomy and axillary dissection under general anaesthesia. Following surgery, the rats were treated in 1 of 3 ways. In the prevention group, 1 cm(3) (0.35 mg) CP solution was injected beneath the skin flap just before closure of the incision after mastectomy. In the treatment group, animals in which a seroma was formed, the fluid was aspirated, and 1 cm(3) CP solution was injected beneath the flap. In the control group, animals in which seromas formed, aspiration only was performed. The frequency of seroma for mation decreased when CP solution was injected immediately after the operation (p < 0.01). In addition, seroma formation was effectively treated by CP injection when compared with the control group (p < 0.05). CP was effective as a prophylactic agent in the prevention group and as a therapeutic agent in the treatment group in this experimental model. CP injection may be useful for the management of this problem in a clinical setting. Copyright (C) 2001 S. Karger AG, Basel.

Modern ooids from the Cleopatra Beach on Island in the Gokova Bay, South Aegean Sea, resemble ooids formed on the Bahamian platform. The concentric coatings of the ooids consist of two or more laminae around a carbonate-or non-carbonate nucleus. The oolite cortex is transparent, whereas the non-transparent portions seem to be the dark fields on the oolitic surfaces. The ooids are mixed with molluscan skeletal debris displaying micritic envelopes. Weakly consolidated ooids have been cemented by calcite in the form of meniscus cement.