9 results on '"Tei TM"'
Search Results
2. Delayed Soft Tissue Reconstruction with a Horizontal Rectus Abdominis Musculocutaneous Flap following Hip Exarticulation.
- Author
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Rødgaard JC and Tei TM
- Abstract
Coverage of large soft tissue defects at the hip region constitutes a challenge for plastic surgeons. We report the case of a 43-year-old female with necrotizing fasciitis of the right thigh, necessitating hip exarticulation and substantial debridement of necrotic tissue. An ipsilateral horizontal rectus abdominis myocutaneous (HRAM) flap was used to cover the defect. The reconstruction was carried out after the attempt of local tissue rearrangement. In light of the successful outcome, we propose that this flap be considered in the future planning of soft tissue reconstruction at the hip region. more...
- Published
- 2013
- Full Text
- View/download PDF
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3. Gracilis muscle transposition for complex fistula and persistent nonhealing sinus in perianal Crohn's disease.
- Author
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Maeda Y, Heyckendorff-Diebold T, Tei TM, Lundby L, and Buntzen S
- Subjects
- Adolescent, Adult, Female, Follow-Up Studies, Humans, Male, Middle Aged, Retrospective Studies, Treatment Outcome, Young Adult, Crohn Disease surgery, Muscle, Skeletal transplantation, Perineum surgery, Rectal Fistula surgery, Wound Healing
- Abstract
Background: Complex fistulas and persistent perineal sinuses as a result of perianal Crohn's disease remain a major therapeutic challenge. A muscle transposition may promote wound healing by filling the perineal cavity and increasing tissue oxygenation. We aimed to evaluate the outcomes of the treatment at our institution over 8 years., Methods: A retrospective review was performed for patients who underwent gracilis muscle transposition for complex perianal Crohn's disease between 1999 and 2007. Data collected included patients' demographic data, previous treatments (medical and surgical), and outcome of the operation. A structured telephone interview was conducted to evaluate medium- to long-term outcomes of the treatment., Results: Eighteen patients (8 men and 10 women, median age 33 years, range 17-59 years) underwent a gracilis muscle transposition between 1999 and 2007. Fourteen patients had a complex fistula, and 4 patients had a persistent nonhealing perineal sinus. Gracilis muscle transposition healed the perineum of 11 patients (61%) at a median follow-up of 10 months (range 1-88 months). The success rate for complex fistulas was 64% and that for persistent nonhealing perineal sinuses was 50%. Eight graft site infections and delayed healing were noted. There were no donor-site problems or major complication. Healing was maintained in 8 of 9 patients who were available for medium- to long-term follow-up (median 64 months, range 23-123 months), with high patient satisfaction., Conclusions: Gracilis transposition is a viable option as a treatment for complex perianal Crohn's disease. Efficacy was maintained in nearly 90% of patients in the medium to long term. more...
- Published
- 2011
- Full Text
- View/download PDF
4. Growth hormone is a stimulating but not an essential factor in healing of colon. A study in GH-deficient dwarf rats.
- Author
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Tei TM, Kissmeyer-Nielsen P, Flyvbjerg A, and Christensen H
- Subjects
- Anastomosis, Surgical, Animals, Colon drug effects, Disease Models, Animal, Female, Rats, Rats, Inbred Lew, Colon surgery, Dwarfism, Pituitary metabolism, Growth Hormone pharmacology, Recombinant Proteins pharmacology, Wound Healing drug effects
- Abstract
Background: Growth hormone (GH) has been implicated as an important factor in the healing and previous studies showed significant strength acceleration of experimental intestinal anastomoses., Aim: To study the healing of experimental colonic anastomoses in GH-deficient rats and to study the potential physiological effects of GH-substitution on healing parameters., Conclusion: Exogenous rhGH treatment started 7 days prior to surgery and continued until day 4 postoperatively accelerates the strength development of the experimental colonic anastomoses in dwarf rats indicating a potent role of growth hormone in colonic healing. However, GH is not essential in the healing process, since anastomotic healing in GH-deficient dwarf rats is like rats with normal pituitary function. more...
- Published
- 2006
- Full Text
- View/download PDF
5. [Use of transpelvic vertical rectus abdominus musculocutaneous flap-plasty in the treatment of anal cancer].
- Author
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Tei TM, Stolzenburg T, Buntzen S, Kjeldsen H, and Laurberg S
- Subjects
- Adult, Aged, Female, Humans, Male, Middle Aged, Neoplasm Recurrence, Local surgery, Retrospective Studies, Treatment Outcome, Wound Healing, Anus Neoplasms surgery, Salvage Therapy, Surgical Flaps
- Published
- 2004
6. Use of the subcutaneously based nasolabial flap in lower eyelid reconstruction.
- Author
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Tei TM and Larsen J
- Subjects
- Humans, Male, Middle Aged, Blepharoplasty methods, Carcinoma, Squamous Cell surgery, Eyelid Neoplasms surgery, Surgical Flaps
- Abstract
A 54-year-old male had a history of approximately 18 months, with a diagnostically proven squamous cell carcinoma of the lower left eyelid. The full-thickness subtotal defect was reconstructed with the Hughes procedure (tarsoconjunctival flap) combined with a subcutaneously based nasolabial flap for skin coverage. To our knowledge, the use of the subcutaneous based nasolabial flap in this context has not been described previously. Use of the nasolabial flap may be considered for eyelid reconstruction. more...
- Published
- 2003
- Full Text
- View/download PDF
7. Use of transpelvic rectus abdominis musculocutaneous flap for anal cancer salvage surgery.
- Author
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Tei TM, Stolzenburg T, Buntzen S, Laurberg S, and Kjeldsen H
- Subjects
- Aged, Anus Neoplasms drug therapy, Anus Neoplasms radiotherapy, Female, Humans, Male, Middle Aged, Neoplasm Recurrence, Local, Neoplasm Staging, Patient Satisfaction, Postoperative Complications etiology, Surgical Wound Dehiscence etiology, Treatment Outcome, Urinary Incontinence, Stress etiology, Wound Healing, Anus Neoplasms surgery, Salvage Therapy, Surgical Flaps
- Abstract
Background: Perineal wounds following abdominoperineal resection (APR), for persistent or locally recurrent anal cancer, are associated with poor healing secondary to irradiation therapy. The results of APR combined with a vertical rectus abdominis musculocutaneous (VRAM) flap transposed transpelvically to cover the perineal defect are presented., Methods: Between 1994 and 2000, 105 patients were diagnosed and treated for anal cancer. Twenty-two (21 per cent) underwent a salvage operation owing to persistent or locally recurrent disease. In eight patients, before 1996, the perineum was closed primarily with serious wound complications in five. In the final 14 patients, primary perineal reconstruction with a VRAM flap was performed., Results: Median age was 65.5 (range 45-78) years. Median follow-up was 14.5 (range 3-41) months. There were no flap-related complications and primary healing was achieved in all patients. Median hospital stay was 17 (range 14-72) days. There were two major complications related to the laparotomy and abdominal closure., Conclusion: Combining the salvage operation with a VRAM flap facilitates primary healing after surgical treatment for persistent or locally recurrent anal cancer. A single-stage primary reconstructive procedure is feasible, with an acceptable complication rate and high level of patient satisfaction., (Copyright 2003 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.) more...
- Published
- 2003
- Full Text
- View/download PDF
8. Growth hormone treatment increases transmural colonic growth in GH-deficient dwarf rats.
- Author
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Tei TM, Kissmeyer-Nielsen P, Christensen H, and Flyvbjerg A
- Subjects
- Animals, Blood Glucose analysis, Blotting, Western, Body Weight drug effects, Colon drug effects, Eating drug effects, Female, Human Growth Hormone physiology, Insulin-Like Growth Factor Binding Proteins blood, Insulin-Like Growth Factor I metabolism, Intestinal Mucosa drug effects, Ligands, Organ Size drug effects, Radioimmunoassay, Rats, Rats, Inbred Lew, Recombinant Proteins pharmacology, Time Factors, Colon growth & development, Growth Hormone deficiency, Human Growth Hormone pharmacology
- Abstract
Growth hormone (GH) has been implicated as an important factor in the growth regulation of several visceral organs including the gastrointestinal tract. Our aim was to study the effects of GH administration on colonic growth in dwarf rats with an isolated GH deficiency. Dwarf rats were treated with recombinant human growth hormone (rhGH; 2.0 mg/kg/day) for four weeks and compared with saline treated dwarf rats and rats with normal pituitary function. The colonic wall composition was measured by means of stereological techniques. RhGH treatment of the dwarf rats increased body weight by 80% and proximal and distal colon weight by 63% and 90%, when compared with placebo treated dwarf rats (P< 0.01). The weight of the proximal colonic mucosa increased by 83% (P< 0.01), submucosa by 78% (P< 0.05), and the muscularis propria by 51% (P< 0.001) in rhGH treated dwarf rats compared with dwarf controls. The weight of the distal colonic mucosa increased by 88% (P< 0.01), submucosa by 88% (P< 0.05) and the muscularis propria by 58% (P< 0.05) compared with dwarf controls. The growth of mucosa involved all mucosal layers, with a 73 and 92% increase in the proximal and distal colon luminal surface area respectively (P< 0.001, P< 0.01). The food consumption, expressed as g/day/100 g BW was 13% higher in dwarf rats receiving rhGH than in placebo treated rats (P< 0.05) and normal control rats (P< 0.05). When weights of the GI tract compartments are corrected for the increase in body weight the effects of GH treatment were small or non-significant. RhGH administration in GH deficient dwarf rats induces visceral growth with a pronounced increase in colonic luminal surface area and growth of all layers of the colonic wall. These findings confirm the important role of GH in the regulation of intestinal growth., (Copyright 2000 Harcourt Publishers Ltd.) more...
- Published
- 2000
- Full Text
- View/download PDF
9. Aseptic laparoscopic colon resection with intraabdominal anastomosis. An experimental study in pigs.
- Author
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Jørgensen LS, Langkilde NC, Møller PK, Mortensen FV, Tei TM, and Jacobsen NO
- Subjects
- Anastomosis, Surgical adverse effects, Animals, Asepsis, Colon pathology, Colon surgery, Disease Models, Animal, Female, Laparoscopy adverse effects, Sensitivity and Specificity, Swine, Anastomosis, Surgical methods, Colectomy methods, Laparoscopy methods
- Abstract
Background: We evaluated a new aseptic method for laparoscopic left colon resection in terms of technical feasibility and outcome., Methods: Ten pigs were operated on under general anesthesia. Pre- and postoperative body weight, stools, behavior, and need for analgesics were recorded. Fourteen days later, the animals were killed. At autopsy, the degree of intraabdominal adhesions was noted. The anastomoses were sent for histological examination. The entire procedure was performed intracorporeally, and no antibiotics were given. After division of the mesocolon, the segment to be resected was invaginated down through the colon. This was facilitated by a custom-made instrument that was introduced into the bowel via the anus; it consisted of a pull-out device and a modified diathermy wire. The anastomosis was completed at the invagination fold by a row of hernia staples that were covered by an interrupted suture. Then the invaginated bowel was transected by the diathermy wire and delivered through the anus., Results: One animal was killed before completion of the operation because of a colonic perforation. The remaining nine animals had an uneventful and rapid recovery. They ate from the 1st postoperative day and gained weight rapidly. Stools were normal after 2 days (median), and normal behaviour was noted in all animals from the 1st postoperative day. At the postmortem examination, intraabdominal adhesions were observed in two animals. In one case, the adhesions extended from a hematoma in the mesentery to the abdominal wall. There were no adhesions to the anastomosis or the colon. In the other case, the anastomosis adhered to the right uterine tube and a loop of small intestines., Conclusions: The method is technically feasible, but a modification is suggested for cases where the invagination is impossible. Recovery after the operation is rapid. more...
- Published
- 1998
- Full Text
- View/download PDF
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