341 results on '"Tchkonia, Tamar"'
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2. Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used.
3. Author Correction: Partial inhibition of mitochondrial complex I ameliorates Alzheimer’s disease pathology and cognition in APP/PS1 female mice
4. Mapping cellular senescence networks in human diabetic foot ulcers
5. Hyperinsulinemia Is Highly Associated With Markers of Hepatocytic Senescence in Two Independent Cohorts.
6. An untapped window of opportunity for glioma: targeting therapy-induced senescence prior to recurrence
7. COVID-19 and cellular senescence
8. List of contributors
9. Interventions that target fundamental aging mechanisms: myths and realities
10. Cellular senescence and senolytics: the path to the clinic
11. BMP4 and Gremlin 1 regulate hepatic cell senescence during clinical progression of NAFLD/NASH
12. Targeting cellular senescence in metabolic disease
13. Targeting senescent cells alleviates obesity‐induced metabolic dysfunction
14. Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans
15. Role of senescence in the chronic health consequences of COVID-19
16. Clinicopathological and cellular senescence biomarkers in chronic stalled wounds.
17. Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity
18. Strategies for late phase preclinical and early clinical trials of senolytics
19. Profiling microRNA expression during senescence and aging: mining for a diagnostic tool of senescent-cell burden
20. Discovery of Senolytics and the Pathway to Early Phase Clinical Trials
21. An inducible p21-Cre mouse model to monitor and manipulate p21-highly-expressing senescent cells in vivo
22. Mechanisms of vascular dysfunction in the interleukin-10–deficient murine model of preeclampsia indicate nitric oxide dysregulation
23. Partial inhibition of mitochondrial complex I ameliorates Alzheimer’s disease pathology and cognition in APP/PS1 female mice
24. Chronic HIV Infection and Aging: Application of a Geroscience-Guided Approach
25. Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis
26. Potential Clinical Implications of Senotherapies for Cardiovascular Disease
27. Cell senescence, the senescence-associated secretory phenotype, and cancers
28. Post hoc pooled analyses of open-label and randomized controlled trials of senolytics dasatinib and quercetin in Idiopathic Pulmonary Fibrosis
29. P-091 Senescence features in pre-malignant plasma cells and their microenvironment are associated with stable disease in MGUS and SMM
30. Cellular senescence in aging and age-related diseases: Implications for neurodegenerative diseases
31. Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner
32. The Way Forward: Translation
33. Biology of premature ageing in survivors of cancer
34. TRANSPLANTATION OF OLDER ORGANS TRANSFERS SENESCENCE
35. Key elements of cellular senescence involve transcriptional repression of mitotic and DNA repair genes through the p53-p16/RB-E2F-DREAM complex
36. In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers
37. Senescent Cells: A Therapeutic Target in Cardiovascular Diseases
38. Abstract 331: Clearance Of Senescent Cells Reduces Osteogenic And Fibrogenic Signaling In Fibrocalcific Aortic Valve Stenosis
39. A chronic wound model to investigate skin cellular senescence
40. Ex Vivo Perfusion of Discarded Donor Liver Segments for Comparative Therapeutic Investigations
41. Supplementary Figure from Selective Vulnerability of Senescent Glioblastoma Cells to BCL-XL Inhibition
42. Supplementary Data from Selective Vulnerability of Senescent Glioblastoma Cells to BCL-XL Inhibition
43. Data from Selective Vulnerability of Senescent Glioblastoma Cells to BCL-XL Inhibition
44. Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used
45. In vitroandin vivoeffects of zoledronate on senescence and senescence-associated secretory phenotype markers
46. Abstract PR012: Pre-malignant plasma cells exhibit a senescence-like phenotype and accumulation of transposable elements
47. Abstract B020: Pre-malignant plasma cells exhibit a senescence-like phenotype and accumulation of transposable elements
48. Abstract B023: Enhanced survival and adherence of melphalan-induced senescent-like dormant multiple myeloma cells co-cultured with bone marrow stromal cells
49. MGUS and SMM Plasma Cells Exhibit a Senescence-like Phenotype and Accumulation of Transposable Elements That May Contribute to Disease Progression
50. Enhanced Survival and Adherence of Melphalan-Induced Senescent-like Dormant Multiple Myeloma Cells Co-Cultured with Bone Marrow Stromal Cells
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