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180 results on '"Tazi, Asmaa"'

6. Prevention and management of VZV infection during pregnancy and the perinatal period

Author

Charlier, Caroline, Anselem, Olivia, Caseris, Marion, Lachâtre, Marie, Tazi, Asmaa, Driessen, Marine, Pinquier, Didier, Le Cœur, Chemsa, Saunier, Aurélie, Bergamelli, Mathilde, Gibert Vanspranghels, Roxane, Chosidow, Anaïs, Cazanave, Charles, Alain, Sophie, Faure, Karine, Birgy, André, Dubos, François, Lesprit, Philippe, Guinaud, Julie, Cohen, Robert, Decousser, Jean-Winoc, Grimprel, Emmanuel, Huissoud, Cyril, Blanc, Julie, Kayem, Gilles, Vuotto, Fanny, and Vauloup-Fellous, Christelle

Published
2024
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10. High-level expression of chromosomally encoded SHV-1 β-lactamase reduces the susceptibility to cefiderocol of clinical isolates of Klebsiella pneumoniae

Author

Charfi, Rym, primary, Tazi, Asmaa, additional, Sereme, Youssouf, additional, Plainvert, Céline, additional, Poupet, Hélène, additional, Doloy, Alexandra, additional, Guyonnet, Cécile, additional, Morand, Philippe, additional, Loubinoux, Julien, additional, Poyart, Claire, additional, and Mammeri, Hedi, additional

Published
2024
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15. Multidrug-Resistant Hypervirulent Group B Streptococcus in Neonatal Invasive Infections, France, 2007-2019

Author

Plainvert, Celine, Hays, Constantin, Touak, Gerald, Joubrel-Guyot, Caroline, Dmytruk, Nicolas, Frigo, Amandine, Poyart, Claire, and Tazi, Asmaa

Subjects
Pediatric research, Streptococcus agalactiae -- Research, Streptococcal infections -- Statistics -- Diagnosis, Microbial drug resistance -- Research, Neonatal diseases -- Statistics -- Diagnosis, Health
Abstract

Group B Streptococcus (GBS; Streptococcus agalactiae) is the leading cause of neonatal invasive infections worldwide (1). Despite appropriate antimicrobial drug therapy, the global burden of GBS neonatal infections remains substantial, [...]

Published
2020
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21. CC17 group B Streptococcus exploits integrins for neonatal meningitis development

Author

de Cambronne, Romain Deshayes, Fouet, Agnes, Picart, Amandine, Bourrel, Anne-Sophie, Anjou, Cyril, Bouvier, Guillaume, Candeias, Cristina, Bouaboud, Abdelouhab, Costa, Lionel, Boulay, Anne-Cecile, Cohen-Salmon, Martine, Plu, Isabelle, Rambaud, Caroline, Faurobert, Eva, Albiges-Rizo, Corinne, Tazi, Asmaa, Poyart, Claire, and Guignot, Julie

Subjects
Infants (Newborn) -- Diseases, Bacterial meningitis -- Genetic aspects -- Development and progression -- Care and treatment, Integrins -- Health aspects, Cell receptors -- Health aspects, Health care industry
Abstract

Group B Streptococcus (GBS) is the major cause of human neonatal infections. A single clone, designated CC17-GBS, accounts for more than 80% of meningitis cases, the most severe form of the infection. However, the events allowing blood- borne GBS to penetrate the brain remain largely elusive. In this study, we identified the host transmembrane receptors [alpha]5[beta]1 and [alpha]v[beta]3 integrins as the ligands of Srr2, a major CC17-GBS-specific adhesin. Two motifs located in the binding region of Srr2 were responsible for the interaction between CC17-GBS and these integrins. We demonstrated in a blood-brain- barrier cellular model that both integrins contributed to the adhesion and internalization of CC17-GBS. Strikingly, both integrins were overexpressed during the postnatal period in the brain vessels of the blood-brain barrier and blood-cerebrospinal fluid barrier and contributed to juvenile susceptibility to CC17 meningitis. Finally, blocking these integrins decreased the ability of CC17-GBS to cross into the CNS of juvenile mice in an in vivo model of meningitis. Our study demonstrated that CC17-GBS exploits integrins in order to cross the brain vessels, leading to meningitis. Importantly, it provides host molecular insights into neonate's susceptibility to CC17-GBS meningitis, thereby opening new perspectives for therapeutic and prevention strategies of GBS-elicited meningitis., Introduction In the early 1950s, because of the massive utilization of tetracyclines, Streptococcus agalactiae (group B Streptococcus, GBS) emerged worldwide as the most significant pathogen causing severe neonatal invasive infections [...]

Published
2021
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22. Hypervirulent Klebsiella Pneumoniae, an Emerging Cause of Endogenous Endophthalmitis in A French Center: A Comparative Cohort Study.

Author

Martellosio, Jean-Philippe, Gastli, Nabil, Farhat, Rebecca, Tazi, Asmaa, Duraffour, Pierre, Rossi, Benjamin, Canouï, Etienne, Morbieu, Caroline, Billoët, Annick, Mouthon, Luc, Poyart, Claire, Brézin, Antoine, and Legendre, Paul

Subjects
KLEBSIELLA pneumoniae, ENDOPHTHALMITIS, COHORT analysis, COMPARATIVE studies
Abstract

Klebsiella pneumoniae (KP) is the most common cause of endogenous endophthalmitis (EE) in Asia, but data in Europe are scarce. We describe eight cases of KP EE compared to a cohort of EE in a French center. EE cases were retrospectively studied between January 2014 and January 2021. KP EE cases were analyzed to assess clinical, microbiological features, and outcome. Among the 33 EE cases identified, the first causative agent (24%, n = 8) was KP, mainly (7/8) with hypervirulent phenotype (hvKP). All but one of these cases occurred from December 2019 to January 2021. Contrary to non-KP patients, KP patients had multiple extraocular infective foci (p =.006), all presented with liver abscesses (p <.001), 50% had cerebral involvement (p =.13). Visual outcome was poor in both groups. KP is an emerging cause of EE in a French center, consistently associated with liver abscesses, frequent cerebral involvement, and predominance of hvKP strains. [ABSTRACT FROM AUTHOR]

Published
2023
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24. eOSCE stations live versus remote evaluation and scores variability

Author

Bouzid, Donia, Mullaert, Jimmy, Ghazali, Aiham, Ferré, Valentine Marie, Mentré, France, Lemogne, Cédric, Ruszniewski, Philippe, Faye, Albert, Dinh, Alexy Tran, Mirault, Tristan, Smadja, Nathan Peiffer, Muller, Léonore, Pierrotin, Laure Falque, Thy, Michael, Assadi, Maksud, Yung, Sonia, de Tymowski, Christian, Le Hingrat, Quentin, Eyer, Xavier, Wicky, Paul Henri, Oualha, Mehdi, Houdouin, Véronique, Jabre, Patricia, Vodovar, Dominique, Burgio, Marco Dioguardi, Zucman, Noémie, Tsopra, Rosy, Tazi, Asmaa, Ressaire, Quentin, Nguyen, Yann, Girard, Muriel, Frachon, Adèle, Depret, François, Pellat, Anna, de Masson, Adèle, Azais, Henri, de Castro, Nathalie, Jeantrelle, Caroline, Javaud, Nicolas, Malmartel, Alexandre, de Margerie, Constance Jacquin, Chousterman, Benjamin, Fournel, Ludovic, Holleville, Mathilde, Blanche, Stéphane, Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, Institut de psychiatrie et neurosciences de Paris (IPNP - U1266 Inserm), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Hôpital Beaujon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), AP-HP Hôpital universitaire Robert-Debré [Paris], CIC Hôpital Bichat, AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-UFR de Médecine, Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Health data- and model- driven Knowledge Acquisition (HeKA), Inria de Paris, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)-École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité), and Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138))

Subjects
[SHS.EDU]Humanities and Social Sciences/Education, General Medicine, Education
Abstract

Background Objective structured clinical examinations (OSCEs) are known to be a fair evaluation method. These recent years, the use of online OSCEs (eOSCEs) has spread. This study aimed to compare remote versus live evaluation and assess the factors associated with score variability during eOSCEs. Methods We conducted large-scale eOSCEs at the medical school of the Université de Paris Cité in June 2021 and recorded all the students’ performances, allowing a second evaluation. To assess the agreement in our context of multiple raters and students, we fitted a linear mixed model with student and rater as random effects and the score as an explained variable. Results One hundred seventy observations were analyzed for the first station after quality control. We retained 192 and 110 observations for the statistical analysis of the two other stations. The median score and interquartile range were 60 out of 100 (IQR 50–70), 60 out of 100 (IQR 54–70), and 53 out of 100 (IQR 45–62) for the three stations. The score variance proportions explained by the rater (ICC rater) were 23.0, 16.8, and 32.8%, respectively. Of the 31 raters, 18 (58%) were male. Scores did not differ significantly according to the gender of the rater (p = 0.96, 0.10, and 0.26, respectively). The two evaluations showed no systematic difference in scores (p = 0.92, 0.053, and 0.38, respectively). Conclusion Our study suggests that remote evaluation is as reliable as live evaluation for eOSCEs.

Published
2022

25. Hypervirulent Klebsiella Pneumoniae, an Emerging Cause of Endogenous Endophthalmitis in A French Center: A Comparative Cohort Study

Author

Martellosio, Jean-Philippe, primary, Gastli, Nabil, additional, Farhat, Rebecca, additional, Tazi, Asmaa, additional, Duraffour, Pierre, additional, Rossi, Benjamin, additional, Canouï, Etienne, additional, Morbieu, Caroline, additional, Billoët, Annick, additional, Mouthon, Luc, additional, Poyart, Claire, additional, Brézin, Antoine, additional, and Legendre, Paul, additional

Published
2022
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28. CC17 group B Streptococcus exploits integrins for neonatal meningitis development

Author

Deshayes de Cambronne, Romain, primary, Fouet, Agnès, additional, Picart, Amandine, additional, Bourrel, Anne-Sophie, additional, Anjou, Cyril, additional, Bouvier, Guillaume, additional, Candeias, Cristina, additional, Bouaboud, Abdelouhab, additional, Costa, Lionel, additional, Boulay, Anne-Cécile, additional, Cohen-Salmon, Martine, additional, Plu, Isabelle, additional, Rambaud, Caroline, additional, Faurobert, Eva, additional, Albigès-Rizo, Corinne, additional, Tazi, Asmaa, additional, Poyart, Claire, additional, and Guignot, Julie, additional

Published
2021
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29. Gut mucosa alterations and loss of segmented filamentous bacteria in type 1 diabetes are associated with inflammation rather than hyperglycaemia

Author

Rouland, Matthieu, primary, Beaudoin, Lucie, additional, Rouxel, Ophélie, additional, Bertrand, Léo, additional, Cagninacci, Lucie, additional, Saffarian, Azadeh, additional, Pedron, Thierry, additional, Gueddouri, Dalale, additional, Guilmeau, Sandra, additional, Burnol, Anne-Françoise, additional, Rachdi, Latif, additional, Tazi, Asmaa, additional, Mouriès, Juliette, additional, Rescigno, Maria, additional, Vergnolle, Nathalie, additional, Sansonetti, Philippe, additional, Christine Rogner, Ute, additional, and Lehuen, Agnès, additional

Published
2021
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30. Invasive group B Streptococcus infections in non-pregnant adults: a retrospective study, France, 2007–2019

Author

Vuillemin, Xavier, primary, Hays, Constantin, additional, Plainvert, Céline, additional, Dmytruk, Nicolas, additional, Louis, Mathilde, additional, Touak, Gérald, additional, Saint-Pierre, Benjamin, additional, Adoux, Lucie, additional, Letourneur, Franck, additional, Frigo, Amandine, additional, Poyart, Claire, additional, and Tazi, Asmaa, additional

Published
2021
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33. Gut mucosa alterations and loss of segmented filamentous bacteria in type 1 diabetes are associated with inflammation rather than hyperglycaemia.

Author

Rouland, Matthieu, Beaudoin, Lucie, Rouxel, Ophélie, Bertrand, Léo, Cagninacci, Lucie, Saffarian, Azadeh, Pedron, Thierry, Gueddouri, Dalale, Guilmeau, Sandra, Burnol, Anne-Françoise, Rachdi, Latif, Tazi, Asmaa, Mouriès, Juliette, Rescigno, Maria, Vergnolle, Nathalie, Sansonetti, Philippe, Rogner, Ute Christine, and Lehuen, Agnès

Subjects
TYPE 1 diabetes, AEROBIC bacteria, FILAMENTOUS bacteria, HYPERGLYCEMIA, ELEMENTAL diet, MATRIX-assisted laser desorption-ionization, EPICATECHIN
Published
2022
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34. Persistence of group B Streptococcus vaginal colonization and prevalence of hypervirulent CC-17 clone correlate with the country of birth: a prospective 3-month follow-up cohort study

Author

Plainvert, Céline, primary, Anselem, Olivia, additional, Joubrel, Caroline, additional, Marcou, Valérie, additional, Falloukh, Amiel, additional, Frigo, Amandine, additional, Magdoud El Alaoui, Fatma, additional, Ancel, Pierre-Yves, additional, Jarreau, Pierre Henri, additional, Mandelbrot, Laurent, additional, Goffinet, François, additional, Poyart, Claire, additional, and Tazi, Asmaa, additional

Published
2020
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39. Invasive Group B streptococcal infections in infants, France

Author

Poyart, Claire, Reglier-Poupet, Helene, Tazi, Asmaa, Billoet, Annick, Dmytruk, Nicolas, Bidet, Philippe, Bingen, Edouard, Raymond, Josette, and Trieu-Cuot, Patrick

Subjects
Infants (Newborn) -- Health aspects, Meningitis -- Health aspects
Abstract

Clinical features and molecular characterization of 109 group B streptococci causing neonatal invasive infections were determined over an 18-month period in France. Sixty-four percent of the strains were from late-onset [...]

Published
2008

40. Risk Factors for Infant Colonization by Hypervirulent CC17 Group B Streptococcus: Toward the Understanding of Late-onset Disease

Author

Tazi, Asmaa, primary, Plainvert, Céline, additional, Anselem, Olivia, additional, Ballon, Morgane, additional, Marcou, Valérie, additional, Seco, Aurélien, additional, El Alaoui, Fatma, additional, Joubrel, Caroline, additional, El Helali, Najoua, additional, Falloukh, Emile, additional, Frigo, Amandine, additional, Raymond, Josette, additional, Trieu-Cuot, Patrick, additional, Branger, Catherine, additional, Le Monnier, Alban, additional, Azria, Elie, additional, Ancel, Pierre-Yves, additional, Jarreau, Pierre Henri, additional, Mandelbrot, Laurent, additional, Goffinet, François, additional, and Poyart, Claire, additional

Published
2019
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45. Fluoroquinolone-resistant group B streptococci in acute exacerbation of chronic bronchitis

Author

Tazi, Asmaa, Gueudet, Thomas, Varon, Emanuelle, Gilly, Liliane, Trieu-Cuot, Patrick, and Poyart, Claire

Abstract

To the Editor: Fluoroquinolones (FQs) that are active against streptococcal species (e.g., levofloxacin and moxifloxacin) have been recommended by numerous national health authorities and international organizations for treating acute exacerbations [...]

Published
2008

46. [A breakthrough in the understanding of neonatal group B streptococcus meningitis]

Author

Tazi, Asmaa, Disson, Olivier, Bellais, Samuel, Bouaboud, Abdelouhab, Tardieux, Isabelle, Trieu-Cuot, Patrick, Lecuit, Marc, Poyart, Claire, Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), AP-HP - Hôpital Cochin Broca Hôtel Dieu [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Biologie des Infections - Biology of Infection, Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur [Paris], Biologie des Bactéries pathogènes à Gram-positif, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Université Paris Descartes - Paris 5 (UPD5), Microorganismes et Barrières de l'Hôte (Equipe avenir), Centre d'infectiologie Necker-Pasteur [CHU Necker], Institut Pasteur [Paris]-CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service des Maladies infectieuses et tropicales [CHU Necker], CHU Necker - Enfants Malades [AP-HP], Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), and Institut Pasteur [Paris] (IP)-CHU Necker - Enfants Malades [AP-HP]

Subjects
MESH: Adhesins, Bacterial, [SDV]Life Sciences [q-bio], MESH: Virulence, MESH: Blood-Brain Barrier, MESH: Pregnancy, MESH: Streptococcal Infections, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, MESH: Animals, MESH: Endothelial Cells, MESH: Pregnancy Complications, Infectious, MESH: Bacteremia, MESH: Mice, MESH: Humans, MESH: Infant, Newborn, MESH: Adult, MESH: Streptococcus agalactiae, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, MESH: Meningitis, Bacterial, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, MESH: Vagina, MESH: Epithelial Cells, MESH: Carrier State, MESH: Female, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, MESH: Bacterial Translocation, MESH: Intestines
Abstract

International audience; Le streptocoque du groupe B (SGB, Streptococcus agalactiae) est une bactérie capsulée à Gram positif commensale des voies digestives et vaginales retrouvée chez 20 à 30 % des adultes sains. Son intérêt en médecine humaine réside principalement dans le fait que cette bactérie est la première cause d’infections néonatales invasives (septicémies, méningites) et un pathogène d’importance croissante chez l’adulte, en particulier chez le sujet âgé et les individus porteurs de pathologies sousjacentes

Published
2011

47. Méningite néonatale à streptocoque du groupe B

Author

Tazi, Asmaa, Disson, Olivier, Bellais, Samuel, Bouaboud, Abdelouhab, Tardieux, Isabelle, Trieu-Cuot, Patrick, Lecuit, Marc, Poyart, Claire, Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), AP-HP - Hôpital Cochin Broca Hôtel Dieu [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Biologie des Infections - Biology of Infection, Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur [Paris], Biologie des Bactéries pathogènes à Gram-positif, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Université Paris Descartes - Paris 5 (UPD5), Microorganismes et Barrières de l'Hôte (Equipe avenir), Centre d'infectiologie Necker-Pasteur [CHU Necker], Institut Pasteur [Paris]-CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service des Maladies infectieuses et tropicales [CHU Necker], and CHU Necker - Enfants Malades [AP-HP]

Subjects
MESH: Adhesins, Bacterial, [SDV]Life Sciences [q-bio], MESH: Virulence, MESH: Blood-Brain Barrier, MESH: Pregnancy, MESH: Streptococcal Infections, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, MESH: Animals, MESH: Endothelial Cells, MESH: Pregnancy Complications, Infectious, MESH: Bacteremia, MESH: Mice, MESH: Humans, MESH: Infant, Newborn, MESH: Adult, MESH: Streptococcus agalactiae, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, MESH: Meningitis, Bacterial, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, MESH: Vagina, MESH: Epithelial Cells, MESH: Carrier State, MESH: Female, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, MESH: Bacterial Translocation, MESH: Intestines
Abstract

International audience; Le streptocoque du groupe B (SGB, Streptococcus agalactiae) est une bactérie capsulée à Gram positif commensale des voies digestives et vaginales retrouvée chez 20 à 30 % des adultes sains. Son intérêt en médecine humaine réside principalement dans le fait que cette bactérie est la première cause d’infections néonatales invasives (septicémies, méningites) et un pathogène d’importance croissante chez l’adulte, en particulier chez le sujet âgé et les individus porteurs de pathologies sousjacentes

Published
2011

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