40 results on '"Tassone, Giusy"'
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2. Catechol-O-methyltransferase (COMT)
3. The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents
4. Dimerization of the C-type lectin-like receptor CD93 promotes its binding to Multimerin-2 in endothelial cells
5. 1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity
6. Metal Ion Binding to Human Glutaminyl Cyclase: A Structural Perspective.
7. A Facile Access to Green Fluorescent Albumin Derivatives
8. STUDI STRUTTURALI E FUNZIONALI DEL RECETTORE CD93.
9. The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents
10. Probing the role of Arg97 in Heat shock protein 90 N-terminal domain from the parasite Leishmania braziliensis through site-directed mutagenesis on the human counterpart
11. Chapter 2.5 - Catechol-O-methyltransferase (COMT)
12. Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery–Genetics Alliance Perspective
13. X-ray Crystallography Contributions to Drug Discovery Against Parasite
14. Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates
15. Exploiting ELIOT for Scaffold-Repurposing Opportunities: TRIM33 a Possible Novel E3 Ligase to Expand the Toolbox for PROTAC Design
16. Structural Basis of Parasitic HSP90 ATPase Inhibition by Small Molecules
17. Front Cover: Mechanistic Aspects of the Asymmetric Transfer Hydrogenation in the Manufacture of Noradrenaline (Eur. J. Org. Chem. 36/2022)
18. Structural Characterization of Human Heat Shock Protein 90 N-Terminal Domain and Its Variants K112R and K112A in Complex with a Potent 1,2,3-Triazole-Based Inhibitor
19. Mechanistic Aspects of the Asymmetric Transfer Hydrogenation in the Manufacture of Noradrenaline
20. 1,2,4‐Triazole‐3‐Thione Analogues with a 2‐Ethylbenzoic Acid at Position 4 as VIM‐type Metallo‐β‐Lactamase Inhibitors
21. Contributors
22. Xanthopsin‐Like Systems via Site‐Specific Click‐Functionalization of a Retinoic Acid Binding Protein
23. Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin
24. Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase
25. Validation of Recombinant Chicken Liver Bile Acid Binding Protein as a Tool for Cholic Acid Hosting
26. Dynamic Interplay between Copper Toxicity and Mitochondrial Dysfunction in Alzheimer’s Disease
27. Structural Bases for the Synergistic Inhibition of Human Thymidylate Synthase and Ovarian Cancer Cell Growth by Drug Combinations
28. Discovery of ANT3310, a Novel Broad-Spectrum Serine β-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii
29. High-resolution crystal structure of Trypanosoma brucei pteridine reductase 1 in complex with an innovative tricyclic-based inhibitor
30. Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein–Protein Interaction
31. Discovery of small molecule inhibitors of Leishmania braziliensis Hsp90 chaperone
32. Xanthopsin‐Like Systems via Site‐Specific Click‐Functionalization of a Retinoic Acid Binding Protein.
33. Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase, a validated target towards Alzheimer disease
34. Probing the role of Arg97 in the parasite Leishmania braziliensis Hsp90 through site directed mutagenesis on the human counterpart
35. Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase for the treatment of Alzheimer disease
36. Small Molecules as Potential Inhibitors of the 14-3-3/c-Abl Interaction for the Treatment of CML
37. Targeting Methyltransferases in Human Pathogenic Bacteria: Insights into Thymidylate Synthase (TS) and Flavin-Dependent TS (FDTS)
38. Structural Comparison of Enterococcus faecalis and Human Thymidylate Synthase Complexes with the Substrate dUMP and Its Analogue FdUMP Provides Hints about Enzyme Conformational Variabilities
39. Chemically stable inhibitors of 14-3-3 protein–protein interactions derived from BV02
40. Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.
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