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714 results on '"Tassinari, C."'

9. U-Pb zircon SHRIMP data from the Cana Bravalayered complex: new constraints for themafic-ultramafic intrusions of Northern Goiás,Brazil

Author

Giovanardi T., Girardi V. A. V., Correia C. T., Sinigoi S., Tassinari C. C. G., and Mazzucchelli M.

Subjects
cana brava, layered complex, geochemistry, zircon, shrimp, Geology, QE1-996.5
Abstract

The Cana Brava Complex is the northernmostand least well known layered intrusion of a discontinuousbelt of mafic-ultramafic massifs within the Brasilia Belt,which also comprises theNiquelândia and Barro Alto complexes.Available geochronological data from a range oftechniques (K/Ar, Ar/Ar, Rb/Sr, Sm/Nd and U/Pb) providea range of possible ages (time span from 3.9 Ga to 450 Ma),hence a precise and reliable age for the Cana Brava Complexis still lacking. Also, preliminary isotopic and geochemicaldata of the Cana Brava Complex suggest a significantcrustal contamination, which could have affectedbulk-rock Sr and Nd systematics resulting in meaninglessage determinations. In this paper, we present new U-PbSHRIMP zircon analyses from four samples of differentunits of the Cana Brava Complexwhich suggest that the intrusionoccurred during the Neoproterozoic, between 800and 780 Ma, i.e. at the same age ofNiquelândia. Discordantolder 206Pb/238U ages are provided by inherited zircons,and match the age of the metamorphism of the embeddingPalmeirópolis Sequence.

Published
2015
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12. Geodynamic evolution of the SW Variscides: orogenic collapse shown by new tectonometamorphic and isotopic data from western Ossa-Morena Zone, SW Iberia

Author

Rosas, F.M., Marques, F.O., Ballevre, M., and Tassinari, C.

Subjects
Iberian Peninsula -- Natural history, Orogeny -- Evaluation, Shear zones -- Natural history, Morphotectonics -- Research, Geodynamics -- Research, Earth sciences
Abstract

The pre-Mesozoic geodynamic evolution of SW Iberia has been investigated on the basis of detailed structural analysis, isotope dating, and petrologic study of high-pressure (HP) rocks, revealing the superposition of several tectonometalnorphic events: (1) An HP event older than circa 358 Ma is recorded in basic rocks preserved inside marbles, which suggests subduction of a continental margin. The defonnation associated with this stage is recorded by a refractory graphite fabric and noncoaxial mesoscopic structures found within the host metasediments. The sense of shear is top to south, revealing thrusting synthetic with subduction (underthrusting) to the north. (2) Recrystallization before circa 358 Ma is due to a regional-scale thermal episode and magmatism. (3) Noncoaxial deformation with top to north sense of shear in northward dipping large-scale shear zones is associated with pervasive hydration and metamorphic retrogression under mostly greenschist facies. This indicates exhumation by normal faulting in a detachment zone confined to the top to north and north dipping shear zones during postorogenic collapse soon after 358 Ma ago (inversion of earlier top to south thrusts). (4) Static recrystallization at circa 318 Ma is due to regional-scale granitic intrusions.

Published
2008

32. Single-blind, placebo-controlled multicenter trial of vigabatrin in the treatment of epilepsy

Author

Loeb C., Iudice A., Percucca E., Gnanasakthy A., Angeleri F., Scarpino O., Avanzini G., Binelli D., Baruzzi A., Procaccianti G., Bergamasco B., Bianco C., Canger R., Mai R., Di Perri R., Pisani F., Cocito L., Manfredi M., Faedda M. T., Mutani R., Gianelli M., Tartara A., Perucca E., Tassinari C. A., Michelucci R., Zappoli R., Zaccara G., Gnanasakthy A., Iudice A., Matthews J., Mumford J. P., and The Italian Study Group on Vigabatrin

Published
1992
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34. Italian daily platelet transfusion practice for haematological patients undergoing high dose chemotherapy with or without stem cell transplantation: a survey by the GIMEMA Haemostasis and Thrombosis Working Party

Author

Tagariello, G, Castaman, G, Falanga, A, Santoro, R, Napolitano, M, Storti, S, Veneri, D, Basso, M, Candiotto, L, Tassinari, C, Federici, AB, De Stefano, V, Tagariello, G., Castaman, G., Falanga, A., Santoro, R., Napolitano, M., Storti, S., Veneri, D., Basso, M., Candiotto, L., Tassinari, C., Federici, A., De Stefano, V., Tagariello, G, Castaman, G, Falanga, A, Santoro, R, Napolitano, M, Storti, S, Veneri, D, Basso, M, Candiotto, L, Tassinari, C, Federici, A, and De Stefano, V

Subjects
Settore MED/15 - MALATTIE DEL SANGUE, Bone marrow transplantation, Prophylaxis, Bleeding, High-dose chemotherapy, Platelet transfusion, Immunology and Allergy, Hematology, bleeding, platelet transfusion, prophylaxis, high-dose chemotherapy, bone marrow transplantation, Original Article, Prophylaxi
Abstract

Background. Following high-dose chemotherapy/bone marrow transplantation, patients are routinely, prophylactically transfused with platelet concentrates (PC) if they have a platelet count ≤10×109/L or higher in the presence of risk factors for bleeding. However, whether such transfusions are necessary in clinically stable patients with no bleeding, or whether a therapeutic transfusion strategy could be sufficient and safe, is still debated. Materials and methods. The GIMEMA Haemostasis and Thrombosis Working Party sent a questionnaire to Italian haematology departments to survey several aspects of daily platelet transfusion practice, such as the cut-off platelet count for transfusion, the evaluation of refractoriness and the type of PC administered. Results. The questionnaire was answered by 18 out of 31 centres (58%). A total of 23,162 PC were transfused in 2,396 patients in 2013. The vast majority of centres (95%) transfused PC according to Italian and international guidelines; only a few transfused always at platelet counts ≤20×109/L. The broad agreement on platelet count cut-off for transfusion (≤10×109/L) was not confirmed when the World Health Organization (WHO) bleeding score was considered: only a third of centres (33%) used transfusions as recommended when the bleeding grade was ≥2. Platelet refractoriness was poorly monitored and most centres (89%) evaluated, mostly empirically (67%), response to transfusion only 24 hours later. Thirty percent of centres transfused platelets in asymptomatic refractory patients. Discussion. Although most Italian haematology departments transfuse PC according to Italian and international guidelines, our survey shows that in routine daily practice physicians do not comply closely with the WHO recommendations on platelet transfusions and monitoring platelet refractoriness. This causes excessive platelet transfusions, with a resulting increase of costs and waste of public health resources.

Published
2016

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