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1. Sensitivity of frozen section analysis in patients with ovarian adult granulosa cell tumor, a multi-center study

Author

Ureyen, Isin, Toptas, Tayfun, Tokalıoğlu, Alp, Sahin, Mustafa, Oktar, Okan, Kole, Merve, Alcı, Aysun, Ozturk, Cagatayhan, Ozmen, Fatma, Akturk, Selin Esen, Erdogan, Ozgur, Ersak, Burak, Kilic, Fatih, Bas, Sevda, Cakir, Caner, Kocak, Ozgur, Kilic, Çiğdem, Ucar, Gokhan, Korkmaz, Vakkas, Narin, Mehmet Ali, Uncu, Dogan, Sanci, Muzaffer, Kimyon Comert, Gunsu, Ozdal, Bulent, Tekin Moralıoglu, Ozlem, Engin Ustun, Yaprak, Boran, Nurettin, Taskin, Salih, Tasci, Tolga, Ortac, Firat, and Turan, Taner

Published
2024
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2. Defining the relationship between ovarian adult granulosa cell tumors and synchronous endometrial pathology: Does ovarian tumor size correlate with endometrial cancer?

Author

Tokalioglu, Abdurrahman Alp, primary, Oktar, Okan, additional, Sahin, Mustafa, additional, Ozturk, Cagatayhan, additional, Erdogan, Ozgur, additional, Yildirim, Hande Esra Koca, additional, Ucar, Yesim, additional, Kilic, Fatih, additional, Ersak, Burak, additional, Yalcin, Necim, additional, Ozmen, Fatma, additional, Alci, Aysun, additional, Bas, Sevda, additional, Gorgulu, Goksen, additional, Selcuk, Ilker, additional, Ucar, Gokhan, additional, Kocak, Ozgur, additional, Cakir, Caner, additional, Kilic, Cigdem, additional, Comert, Gunsu Kimyon, additional, Ureyen, Isin, additional, Toptas, Tayfun, additional, Narin, Mehmet Ali, additional, Tasci, Tolga, additional, Taskin, Salih, additional, Boran, Nurettin, additional, Ozdal, Bulent, additional, Sanci, Muzaffer, additional, Uncu, Dogan, additional, Korkmaz, Vakkas, additional, Tekin, Ozlem Moraloglu, additional, Ustun, Yaprak, additional, Ortac, Fırat, additional, and Turan, Taner, additional

Published
2024
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3. Comparison of two intraoperative examination methods for the diagnosis of sentinel lymph node metastasis in clinically early stage endometrial cancer: A Turkish Gynecologic Oncology Group Study (TRSGO-SLN-003)

Author

Taşkın, Salih, Varlı, Bulut, Altın, Duygu, Takmaz, Özgüç, Vatansever, Doğan, Ersöz, Cevriye Cansız, Turan, Hasan, Bulutay, Pınar, Zeren, Handan, Havare, Semiha Battal, Karabük, Emine, Naki, Murat, Güngör, Mete, Köse, Faruk, Ortaç, Fırat, Arvas, Macit, Ayhan, Ali, and Taşkıran, Çağatay

Published
2021
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6. Is adjuvant chemotherapy necessary for 2014 FIGO stage IC adult granulosa cell tumor?: Multicentric Turkish study.

Author

Erdogan, Ozgur, Kilic, Cigdem, Cakir, Caner, Kilic, Fatih, Oktar, Okan, Ersak, Burak, Sahin, Mustafa, Tokalioglu, Alp, Kocak, Ozgur, Ozturk, Cagatayhan, Gorgulu, Goksen, Gokkaya, Mustafa, Selcuk, Ilker, Korkmaz, Vakkas, Comert, Gunsu Kimyon, Toptas, Tayfun, Ureyen, Isin, Ucar, Gokhan, Taskin, Salih, and Tasci, Tolga

Subjects
GRANULOSA cell tumors, ADJUVANT chemotherapy, TUMOR classification, ADULTS, PROGRESSION-free survival
Abstract

Aim: The aim of our study is to examine the clinical, surgical, and pathological factors of stage 1C adult granulosa cell tumor (AGCT) patients and to investigate the effects of adjuvant therapy on recurrence and survival rates in this patient group. Methods: Out of a total of 415 AGCT patients treated by 10 tertiary oncology centers participating in the study, 63 (15.2%) patients with 2014 FIGO stage IC constituted the study group. The FIGO 2014 system was used for staging. Patient group who received adjuvant chemotherapy was compared with patient group who did not receive adjuvant chemotherapy in terms of disease‐free survival (DFS), and disease‐specific survival. Results: The 5‐year DFS of the study cohort was 89%, and the 10‐year DFS was 85%. Those who received adjuvant chemotherapy and those who did not were similar in terms of clinical, surgical and pathological factors, except for peritoneal cytology. In the univariate analysis, none of the clinical, surgical or pathological factors were significant for DFS. Adjuvant chemotherapy and type of treatment protocol had no impact on DFS. Conclusion: Adjuvant chemotherapy was not associated with improved DFS and overall survival in stage IC AGCT. Multicentric and randomized controlled studies are needed for early stage AGCT in order to confirm these results and reach accurate conclusions. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Determining post-operative morbidity and mortality following gynecological oncology surgery: protocol for a multicenter, international, prospective cohort study (Global Gynaecological Oncology Surgical Outcomes Collaborative—GO SOAR)

Author

Gaba, Faiza, Bizzarri, Nicolò, Kamfwa, Paul, Saiz, Allison, Blyuss, Oleg, Paranjothy, Shantini, Ramirez, Pedro T, Cibula, David, Elshami, Mohamedraed, Saad, Mahmoud, Nafea, Ahmed, Elhadi, Muhammed, Ismail, Alaa, Al-Naggar, Hamza, Cecilia, Darin Maria, Lanner, Maximilian, Pletnev, Andrei, Refky, Basel, Elkady, Abdelazez, Karkour, Tarek, Ali, Hazim Salah, Ghozy, Sherief, Daghash, Sameh, Elmelegy, Mohamed Hamed, Monier, Eman, Mohammad, Mohammad Abdel-Rahman, Ferraioli, Domenico, Nikolova, Tanja, Petousis, Stamatios, Theofanakis, Charalampos, Mishra, Jagannth, Annapurna, Vadaparty, Ifthikar, Mariam Anjum, Ghosh, Anik, Vallabhaneni, Ajay Chanakya, Kar, Bijoy, Al-khafaji, Alyaa, Al-Isawi, Ali, O’Leary, Michael, Martinelli, Fabio, Arcieri, Martina, Restaino, Stefano, Fagotti, Anna, Cola, Edoardo, Bogliolo, Stefano, Shatnawi, Qais, Zazo, Aya, Sindiani, Amer Mahmoud, Alsardieh, Wafa, Qasem, Abdulrahman, Husain, Shatha, Kamarudin, Maherah, Korch, Moniba, Lawal, Ishak, Okunowo, Adeyemi, Alkronz, Mohammed, Lago, Victor, Alsattari, Amani, Abuzaina, Khalil, Shahin, Farah, Aljuba, Ayat, Hatab, Waleed Abu, Salameh, Najib, Radi, Adnan, Casanova, João, Zalewski, Kamil, Yousif, Amel, Govorov, Igor, Abu-Zaid, Ahmed, Alghamdi, Susan, Moreno, Antonio Gil, Rodriguez, Natalia, Boria, Felix, Razumova, Zoia, Alshehabi, Zuheir, Hassan, Bassam, Nawfal, Hamdi, Hamza, Amr, Aker, Seda Şahin, Taskin, Salih, Kahramanoglu, Ilker, Selcuk, Ilker, Gurumurthy, Mahalakshmi, Cairns, Mary, McPherson, Lori, Ghaem-Maghami, Sadaf, Butler, John, Ang, Christine, Sharma, Aarti, Al-Naggar, Hamza, Saif, Sara, Abualdahab, Noor, Qaderi, Shohra, Fundafunda, Swali V, Awad, Mohammed, Karout, Lina, Kassab, Mohamad B, Safar, Ali, Abdallah, Reem, Hatoum, Sana, Elmakkaoui, Said Mohamad, Itani, Rania, El Hassan, Jihad, Karout, Samar, Edine, Hussein Mansour Jamal, Atallah, David, Kacimi, Salah Eddine Oussama, Mohamed, Mustafa, Tan, Chee Yang, Haidar, Hanan, Shehada, Wafaa, Abou-Taleb, Hisham Ahmed, Herdan, Mohamed O., Ali, Ali Hussien, Ahmed, Ahmed Ragab Ali, Mohamed, Omar Salah Ibrahim, Omar, Mohamed I, Zineldin, Eman Ibrahim, El-hamouly, Ahmed Sabry Fouad, Hajjaj, Baraa N., Yousef, Shukri Odeh, Shaheen, Besan, Elhossini, Akram, Obiedat, Ziena, Alsumadi, Maen, Ahmed, Bisan, Abed, Salsabeel, Husaini, Akram, Abusharkh, Subhi Maher, and Angeles, Martina Aida

Published
2021
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9. #356 Sensitivity of frozen section analysis in patients with ovarian adult granulosa cell tumor, a multi-center study

Author

Ureyen, Isin, primary, Toptas, Tayfun, additional, Tokalioglu, Alp, additional, Oktar, Okan, additional, Kole, Merve Cakir, additional, Kilic, Fatih, additional, Bas, Sevda, additional, Kocak, Ozgur, additional, Kilic, Cigdem, additional, Narin, Mehmet Ali, additional, Uncu, Dogan, additional, Sanci, Muzaffer, additional, Ozdal, Bulent, additional, Tekin, Özlem Moraloglu, additional, Ustun, Yaprak Engin, additional, Boran, Nurettin, additional, Taskin, Salih, additional, Tasci, Tolga, additional, Ortac, Firat, additional, and Turan, Taner, additional

Published
2023
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11. #104 Risk factors for sentinel lymph node metastasis in endometrial cancer (TRSGO-SLN-010)

Author

Yalcin, Ibrahim, primary, Taskin, Salih, additional, Takmaz, Ozguc, additional, Demirkiran, Fuat, additional, Gungor, Mete, additional, Tokgozoglu, Nedim, additional, Karabuk, Emine, additional, Bese, Tugan, additional, Altin, Duygu, additional, Turan, Hasan, additional, Kahramanoglu, Ilker, additional, Vatansever, Dogan, additional, Celik, Cetin, additional, Kose, Faruk, additional, Sozen, Hamdullah, additional, Topuz, Samet, additional, Arvas, Macit, additional, Ortac, Firat, additional, Ayhan, Ali, additional, and Taskiran, Cagatay, additional

Published
2023
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12. #668 Evaluation of vulvar squamous cell and glandular cell cancers, retrospective multicenter study

Author

Güngördük, Kemal, primary, Demirkiran, Fuat, additional, Khatip, Ghanim, additional, Öz, Murat, additional, Minareci Özgür Tosun, Yagmur, additional, Taskin, Salih, additional, Akman, Levent, additional, Bülent Özçelik, Varol Gülseren, additional, Dogan, Selen, additional, Yalçin, Yakup, additional, Çebi, Sükrü, additional, Vatansever, Dogan, additional, Özarkan, Kemal, additional, Terek, Cosan, additional, Aslan, Koray, additional, Sanci, Muzaffer, additional, Ortaç, Firat, additional, Vardar, Mehmet Ali, additional, Ayhan, Ali, additional, and Arvas, Macit, additional

Published
2023
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15. Is adjuvant chemotherapy necessary for 2014 FIGO stage IC adult granulosa cell tumor?: Multicentric Turkish study

Author

Erdogan, Ozgur, primary, Kilic, Cigdem, additional, Cakir, Caner, additional, Kilic, Fatih, additional, Oktar, Okan, additional, Ersak, Burak, additional, Sahin, Mustafa, additional, Tokalioglu, Alp, additional, Kocak, Ozgur, additional, Ozturk, Cagatayhan, additional, Gorgulu, Goksen, additional, Gokkaya, Mustafa, additional, Selcuk, Ilker, additional, Korkmaz, Vakkas, additional, Comert, Gunsu Kimyon, additional, Toptas, Tayfun, additional, Ureyen, Isin, additional, Ucar, Gokhan, additional, Taskin, Salih, additional, Tasci, Tolga, additional, Uncu, Dogan, additional, Narin, Mehmet Ali, additional, Boran, Nurettin, additional, Ozdal, Bulent, additional, Tekin, Ozlem Moraloglu, additional, Ustun, Yaprak, additional, Sancı, Muzaffer, additional, Ortac, Firat, additional, and Turan, Taner, additional

Published
2023
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16. Neoadjuvant chemotherapy in patients with stage IVB uterine serous carcinoma: a Turkish multicentric study.

Author

Unsal, Mehmet, Kilic, Cigdem, Cakir, Caner, Kilic, Fatih, Ersak, Burak, Karakas, Sema, Tokgozoglu, Nedim, Varli, Bulut, Oktar, Okan, Kimyon Comert, Gunsu, Ozdemir, Isa Aykut, Boran, Nurettin, Toptas, Tayfun, Ureyen, Isin, Korkmaz, Vakkas, Taskin, Salih, Moraloglu Tekin, Ozlem, Ustun, Yaprak, Tasci, Tolga, and Ortac, Firat

Subjects
LYMPHADENECTOMY, NEOADJUVANT chemotherapy, LYMPHATIC metastasis, GYNECOLOGIC oncology, PROGNOSIS, PROGRESSION-free survival, OVARIAN cancer, ADNEXAL diseases
Abstract

The aim of this study was to evaluate the prognostic factors for and determine the effect of neoadjuvant chemotherapy (NACT) on oncologic outcome in stage IVB pure serous endometrial carcinoma patients who received taxane and platinum. Forty-two patients with 2009 International Federation of Gynecology and Obstetrics (FIGO) stage IVB uterine serous carcinoma were enrolled from six gynecologic oncology centers and a study group was created. The study group had a 2-year disease-free survival (DFS) of 32% and 2-year disease-specific survival (DSS) of 73%. On univariate analysis; lymphadenectomy (not performed vs. performed), paraaortic lymph node metastasis (positive vs. negative) and number of metastatic lymph node count (≤5 vs. >5) were found to have statistical significance for DFS (p < 0.001, p = 0.026 and p = 0.044, respectively). Adnexal metastasis (positive vs. negative) and type of cytoreductive surgery (maximal vs. optimal and suboptimal) had statistical significance for DSS (p = 0.041 and p = 0.015, respectively). Receiving NACT did not affect DFS and DSS in stage IVB uterine serous carcinoma patients. As our sample size was small, precise conclusions could not be made for suggesting the use of NACT in advanced stage uterine serous carcinoma. For more accurate results, more randomized controlled studies are needed in this patient group. What is already known on this subject? Endometrial carcinoma is the most common type of gynecologic tract malignancies and usually it is diagnosed at early stages. Although the favorable prognosis, uterine serous carcinoma (USC), one of the rarest subtypes, has a poorer prognosis when compared to other histological subtypes. USC has a propensity to spread beyond pelvis. Due to this aggressive behavior, surgical intervention could not be feasible in advanced stage disease. What do the results of this study add? Our study evaluated the prognostic factors that affect survival in advanced stage USC patients. Also we investigated that neoadjuvant chemotherapy (NACT) could improve oncologic outcomes. Performing lymphadenectomy, presence of paraaortic lymph node and adnexal metastasis, number of metastatic lymph nodes and type of cytoreductive surgery improved survival in advanced stage USC patients. However, NACT did not have a statistical significance as a predictor for disease-specific survival (DSS) and disease-free survival (DFS). What are the implications of these findings for clinical practice and/or further research? Maximal surgical effort should be performed in advanced stage USC according to our results. On the other hand, NACT had no impact on DSS and DFS rates. For this reason, we could not be able to suggest the routine use of NACT in advanced stage USC. But more randomized controlled trials are warranted for confirmation of our results. [ABSTRACT FROM AUTHOR]

Published
2023
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18. The Risk of Recurrence in Endometrial Cancer Patients with Low-Volume Metastasis in the Sentinel Lymph Nodes: A Retrospective Multi-Institutional Study

Author

Buda, Alessandro, primary, Paniga, Cristiana, additional, Taskin, Salih, additional, Mueller, Michael, additional, Zapardiel, Ignacio, additional, Fanfani, Francesco, additional, Puppo, Andrea, additional, Casarin, Jvan, additional, Papadia, Andrea, additional, De Ponti, Elena, additional, Grassi, Tommaso, additional, Mauro, Jessica, additional, Turan, Hasan, additional, Vatansever, Dogan, additional, Gungor, Mete, additional, Ortag, Firat, additional, Imboden, Sara, additional, Garcia-Pineda, Virginia, additional, Mohr, Stefan, additional, Siegenthaler, Franziska, additional, Perotto, Stefania, additional, Landoni, Fabio, additional, Ghezzi, Fabio, additional, Scambia, Giovanni, additional, Taskiran, Cagatay, additional, and Fruscio, Robert, additional

Published
2023
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19. The Risk of Recurrence in Endometrial Cancer Patients with Low-Volume Metastasis in the Sentinel Lymph Nodes: A Retrospective Multi-Institutional Study

Author

Buda, Alessandro, Paniga, Cristiana, Taskin, Salih, Mueller, Michael, Zapardiel, Ignacio, Fanfani, Francesco, Puppo, Andrea, Casarin, Jvan, Papadia, Andrea, De Ponti, Elena, Grassi, Tommaso, Mauro, Jessica, Turan, Hasan, Vatansever, Dogan, Gungor, Mete, Ortag, Firat, Imboden, Sara, Garcia-Pineda, Virginia, Mohr, Stefan, Siegenthaler, Franziska, Perotto, Stefania, Landoni, Fabio, Ghezzi, Fabio, Scambia, Giovanni, Taskiran, Cagatay, Fruscio, Robert, Buda, A, Paniga, C, Taskin, S, Mueller, M, Zapardiel, I, Fanfani, F, Puppo, A, Casarin, J, Papadia, A, De Ponti, E, Grassi, T, Mauro, J, Turan, H, Vatansever, D, Gungor, M, Ortag, F, Imboden, S, Garcia-Pineda, V, Mohr, S, Siegenthaler, F, Perotto, S, Landoni, F, Ghezzi, F, Scambia, G, Taskiran, C, and Fruscio, R

Subjects
endometrial cancer, low-volume metastasis, sentinel lymph node biopsy, ultrastaging, recurrence-free survival, Cancer Research, Oncology, low-volume metastasi, 610 Medicine & health
Abstract

The aim of this study was to assess the impact of low-volume metastasis (LVM) on disease-free survival (DFS) in women with apparent early-stage endometrial cancer (EC) who underwent sentinel lymph node (SLN) mapping. Patients with pre-operative early-stage EC were retrospectively collected from an international collaboration including 13 referring institutions. A total of 1428 patients were included in this analysis. One hundred and eighty-six patients (13%) had lymph node involvement. Fifty-nine percent of positive SLN exhibited micrometastases, 26.9% micrometastases, and 14% isolated tumor cells. Seventeen patients with positive lymph nodes did not receive any adjuvant therapy. At a median follow-up of 33.3 months, the disease had recurred in 114 women (8%). Patients with micrometastases in the lymph nodes had a worse prognosis of disease-free survival compared to patients with negative nodes or LVM. The rate of recurrence was significantly higher for women with micrometastases than those with low-volume metastases (HR = 2.61; p = 0.01). The administration of adjuvant treatment in patients with LVM, without uterine risk factors, remains a matter of debate and requires further evaluation.

Published
2023
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21. Neoadjuvant chemotherapy in patients with stage IVB uterine serous carcinoma: a Turkish multicentric study

Author

Unsal, Mehmet, primary, Kilic, Cigdem, additional, Cakir, Caner, additional, Kilic, Fatih, additional, Ersak, Burak, additional, Karakas, Sema, additional, Tokgozoglu, Nedim, additional, Varli, Bulut, additional, Oktar, Okan, additional, Kimyon Comert, Gunsu, additional, Ozdemir, Isa Aykut, additional, Boran, Nurettin, additional, Toptas, Tayfun, additional, Ureyen, Isin, additional, Korkmaz, Vakkas, additional, Taskin, Salih, additional, Moraloglu Tekin, Ozlem, additional, Ustun, Yaprak, additional, Tasci, Tolga, additional, Ortac, Firat, additional, and Turan, Taner, additional

Published
2022
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22. EP155/#329 Deep cervical injection: a novel technique to increase bilateral sentinel lymph node detection rate in endometrial cancer patients with indocyanine green (TRSGO-SLN-008)

Author

Vatansever, Dogan, primary, Altin, Duygu, additional, Giray, Burak, additional, Taskin, Salih, additional, Donmez, Emin, additional, Tokgözoglu, Nedim, additional, Guler, Abdul Hamid, additional, Tasci, Tolga, additional, Bese, Tugan, additional, Turan, Hasan, additional, Kahramanoglu, Ilker, additional, Yalcin, Ibrahim, additional, Celik, Cetin, additional, Demirkiran, Fuat, additional, Gungor, Mete, additional, Ortac, Firat, additional, Köse, Faruk, additional, Arvas, Macit, additional, Ayhan, Ali, additional, and Taskiran, Cagatay, additional

Published
2022
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23. 2022-RA-963-ESGO The impact of low-volume metastasis on disease-free survival of women with apparent early-stage endometrial cancerunderwent sentinel node biopsy: a retrospective study

Author

Buda, Alessandro A, primary, Paniga, Cristiana, additional, Taskin, Salih, additional, Mueller, Michael, additional, Zapardiel, Ignacio, additional, Fanfani, Francesco, additional, Puppo, Andrea, additional, Papadia, Andrea, additional, de Ponti, Elena, additional, Turan, Hasan, additional, Perotto, Stefania, additional, Gungor, Mete, additional, Ortac, Firat, additional, Imboden, Sara, additional, Ghezzi, Fabio, additional, Scambia, Giovanni, additional, Taskiran, Cagatay, additional, and Fruscio, Robert, additional

Published
2022
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24. OPEC study: An international multicenter study of ovarian preservation in endometrial cancers

Author

Akgor, Utku, primary, Ayhan, Ali, additional, Shushkevich, Alexander, additional, Ozdal, Bulent, additional, Angelou, Kyveli, additional, Akbayır, Ozgur, additional, Kaidarova, Dilyara, additional, Ulrikh, Elena, additional, Stepanyan, Artem, additional, Ortac, Fırat, additional, Aliyev, Shamistan, additional, Ozgul, Nejat, additional, Taranenka, Siarhei, additional, Haberal, Ali, additional, Salman, Coskun, additional, Seyhan, Alper, additional, Selcuk, Ilker, additional, Haidopoulos, Dimitrios, additional, Akıllı, Huseyin, additional, Bolatbekova, Raikhan, additional, Alaverdyan, Areg, additional, Taskin, Salih, additional, Murshudova, Sabina, additional, Batur, Meltem, additional, Berlev, Igor, additional, and Gultekin, Murat, additional

Published
2022
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25. A Turkish Gynecologic Oncology Group study of fertility-sparing treatment for early-stage endometrial cancer

Author

Dursun, Polat, Erkanli, Serkan, Güzel, Ahmet Bariş, Gultekin, Murat, Tarhan, Nefise Cagla, Altundag, Ozden, Demirkiran, Fuat, Beşe, Tugan, Yildirim, Yusuf, Bozdag, Gurkan, Yarali, Hakan, Simsek, Tayyup, Ozcelik, Bulent, Ortaç, Firat, Taskin, Salih, Guvenal, Tevfik, Ozgul, Nejat, Haberal, Ali, Vardar, M. Ali, Dede, Murat, Yenen, Mufit, Altintas, Aytekin, Arvas, Macit, and Ayhan, Ali

Published
2012
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28. The added value of SLN mapping with indocyanine green in low- and intermediate-risk endometrial cancer management: a systematic review and meta-analysis

Author

Burg, Lara C., primary, Verheijen, Shenna, additional, Bekkers, Ruud L.M., additional, IntHout, Joanna, additional, Holloway, Robert W., additional, Taskin, Salih, additional, Ferguson, Sarah E., additional, Xue, Yu, additional, Ditto, Antonino, additional, Baiocchi, Glauco, additional, Papadia, Andrea, additional, Bogani, Giorgio, additional, Buda, Alessandro, additional, Kruitwagen, Roy F.P.M., additional, and Zusterzeel, Petra L.M., additional

Published
2022
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31. Could the Long-Term Oncological Safety of Laparoscopic Surgery in Low-Risk Endometrial Cancer also Be Valid for the High–Intermediate- and High-Risk Patients? A Multi-Center Turkish Gynecologic Oncology Group Study Conducted with 2745 Endometrial Cancer Cases. (TRSGO-End-001)

Author

Vardar, Mehmet Ali, primary, Guzel, Ahmet Baris, additional, Taskin, Salih, additional, Gungor, Mete, additional, Ozgul, Nejat, additional, Salman, Coskun, additional, Kucukgoz-Gulec, Umran, additional, Khatib, Ghanim, additional, Taskiran, Cagatay, additional, Dünder, Ilkkan, additional, Ortac, Firat, additional, Yuce, Kunter, additional, Terek, Cosan, additional, Simsek, Tayup, additional, Ozsaran, Aydın, additional, Onan, Anil, additional, Coban, Gonca, additional, Topuz, Samet, additional, Demirkiran, Fuat, additional, Takmaz, Ozguc, additional, Kose, M. Faruk, additional, Gocmen, Ahmet, additional, Seydaoglu, Gulsah, additional, Gumurdulu, Derya, additional, and Ayhan, Ali, additional

Published
2021
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32. The safety of major gynaecologic cancer surgery without routine preoperative COVID-19 testing in the COVID-19 era: a multicentre, retrospective, case-control study

Author

Oz, Murat, primary, Meydanli, Mehmet Mutlu, additional, Altintas, Mufide Iclal, additional, Akilli, Huseyin, additional, Gultekin, Murat, additional, Ozgul, Nejat, additional, Salman, Mehmet Coskun, additional, Taskin, Salih, additional, Yaprak, Esra, additional, Taskiran, Cagatay, additional, Vatansever, Dogan, additional, Giray, Burak, additional, Yetkinel, Selcuk, additional, Celik, Husnu, additional, Onan, Mehmet Anil, additional, and Ayhan, Ali, additional

Published
2021
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33. The safety of major gynaecologic cancer surgery without routine preoperative COVID-19 testing in the COVID-19 era: a multicentre, retrospective, case-control study.

Author

Oz, Murat, Meydanli, Mehmet Mutlu, Altintas, Mufide Iclal, Akilli, Huseyin, Gultekin, Murat, Ozgul, Nejat, Salman, Mehmet Coskun, Taskin, Salih, Yaprak, Esra, Taskiran, Cagatay, Vatansever, Dogan, Giray, Burak, Yetkinel, Selcuk, Celik, Husnu, Onan, Mehmet Anil, and Ayhan, Ali

Abstract

Our goal was to address the safety of major gynaecologic cancer surgery without routine preoperative COVID-19 testing in the COVID-19 era. The databases of seven gynaecologic cancer centres were searched in order to identify all consecutive gynaecologic cancer patients undergoing major surgery between March 11, 2020 and May 15, 2020 for this retrospective, case-control study. The case group consisted of patients with histopathologically confirmed gynaecologic cancers, and each case was matched with two counterparts who had undergone primary surgery before the COVID-19 pandemic. The case and the control groups were compared in terms of length of hospital stay, admission to the intensive care unit (ICU), intraoperative and postoperative complications. During the study period, 154 women with gynaecologic cancer undergoing major surgery were identified. Although the case group had more co-morbidities compared to the control group (103/154 vs. 178/308, respectively; p =.04), the median length of hospital stays, the rate of ICU admission, intraoperative complication rates and postoperative complication rates were similar in the two groups. Gynaecologic cancer surgery may be performed safely in the COVID-19 era with similar rates of ICU admission, intraoperative and postoperative complications compared to the patients operated before the COVID-19 pandemic. What is already known on this subject? Many societies have announced their guidelines about the surgical management of gynaecologic cancer patients during the COVID-19 pandemic. However, most of them are not evidence-based and mostly on expert opinions. What do the results of this study add? The main findings of this retrospective, case-control study indicate that the short-term (30 day) outcomes of gynaecologic cancer patients undergoing major surgery in the COVID-19 era are similar to those who had been operated before the COVID-19 pandemic. The length of hospital stays, the rates of admission to the ICU, intraoperative and postoperative complications were comparable between women undergoing major gynaecologic cancer surgery in the COVID-19 era and the women who had been operated before the pandemic. What are the implications of these findings for clinical practice and/or further research? We can suggest that definitive surgery may be performed for gynaecologic cancer patients in the COVID-19 era if the resources permit and appropriate precautions such as social distancing, isolation and the use of personal protective equipment are taken. [ABSTRACT FROM AUTHOR]

Published
2022
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39. Impact of cytoreductive surgery on survival of patients with low‐grade serous ovarian carcinoma: A multicentric study of Turkish Society of Gynecologic Oncology (TRSGO‐OvCa‐001)

Author

Vatansever, Dogan, primary, Taskiran, Cagatay, additional, Mutlu Meydanli, Mehmet, additional, Gungorduk, Kemal, additional, Akbayir, Ozgur, additional, Yalcin, Ibrahim, additional, Demirkiran, Fuat, additional, Sozen, Hamdullah, additional, Ozgul, Nejat, additional, Celik, Husnu, additional, Onan, Mehmet Anil, additional, Taskin, Salih, additional, Oge, Tufan, additional, Simsek, Tayyup, additional, Abboud, Sara, additional, Yuksel, Ilkbal Temel, additional, and Ayhan, Ali, additional

Published
2021
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40. Can risk groups accurately predict non‐sentinel lymph node metastasis in sentinel lymph node‐positive endometrial cancer patients? A Turkish Gynecologic Oncology Group Study (TRSGO‐SLN‐004)

Author

Altin, Duygu, primary, Taskin, Salih, additional, Tokgozoglu, Nedim, additional, Vatansever, Dogan, additional, Guler, Adbul H., additional, Gungor, Mete, additional, Tasci, Tolga, additional, Turan, Hasan, additional, Kahramanoglu, Ilker, additional, Yalcin, Ibrahim, additional, Celik, Cetin, additional, Kose, Faruk, additional, Ortac, Firat, additional, Arvas, Macit, additional, Ayhan, Ali, additional, and Taskiran, Cagatay, additional

Published
2020
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42. Can risk groups accurately predict non‐sentinel lymph node metastasis in sentinel lymph node‐positive endometrial cancer patients? A Turkish Gynecologic Oncology Group Study (TRSGO‐SLN‐004).

Author

Altin, Duygu, Taskin, Salih, Tokgozoglu, Nedim, Vatansever, Dogan, Guler, Adbul H., Gungor, Mete, Tasci, Tolga, Turan, Hasan, Kahramanoglu, Ilker, Yalcin, Ibrahim, Celik, Cetin, Kose, Faruk, Ortac, Firat, Arvas, Macit, Ayhan, Ali, and Taskiran, Cagatay

Published
2021
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47. Prognostic Significance of Retroperitoneal Lymphadenectomy, Preoperative Neutrophil Lymphocyte Ratio and Platelet Lymphocyte Ratio in Primary Fallopian Tube Carcinoma: A Multicenter Study

Author

Gungorduk, Kemal, primary, Ertas, Ibrahim E., additional, Ozdemir, Aykut, additional, Akkaya, Emrah, additional, Telli, Elcin, additional, Taskin, Salih, additional, Gokcu, Mehmet, additional, Guzel, Ahmet Baris, additional, Oge, Tufan, additional, Akman, Levent, additional, Toptas, Tayfun, additional, Solmaz, Ulas, additional, Dogan, Askın, additional, Terek, Mustafa Cosan, additional, Sanci, Muzaffer, additional, Ozsaran, Aydin, additional, Simsek, Tayup, additional, Vardar, Mehmet Ali, additional, Yalcin, Omer Tarik, additional, Ozalp, Sinan, additional, Yildirim, Yusuf, additional, and Ortac, Firat, additional

Published
2014
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49. Comparison of Histopathologic Features of Endometrial Cancer Based on Menopausal Status and Safety of Ovarian Preservation in Premenopausal Women.

Author

Kan, Ozgur, Alkilic, Aysegul, Cetindag Aydın, Elif Nazlı, Koyuncu, Kazibe, Taskin, Salih, and Ortac, Firat

Subjects
HISTOPATHOLOGY, ENDOMETRIAL cancer, OVARIAN cancer, COMORBIDITY, PERIMENOPAUSE
Abstract

The aim of this study was to investigate the frequency of coexisting ovarian malignancy and to determine whether ovarian preservation is feasible in premenopausal endometrial cancer (EC) patients. The data of 251 patients with endometrioid type endometrial cancer were retrospectively reviewed. We classified patients into two groups based on menopausal status. Information regarding patient age, preoperative and intraoperative evaluations, pathology reports, and follow-up results were abstracted from medical records. Coexisting ovarian malignancy was detected in 2 (4.3%) of 46 patients in premenopausal group and in 11 (5.3%) of 205 patients in postmenopausal group. Both patients in premenopausal group with coexisting ovarian malignancy had lymph node involvement and grade 2 tumors, while 5 (45.4%) of 11 patients in postmenopausal group had lymph node involvement and 9 (81.8%) of 11 patients had grade 3 tumors. Incidence of coexisting ovarian malignancies in premenopausal women with EC should not be underestimated. Owing to that thorough preoperative evaluation and an extensive intraoperative evaluation is critical for the decision of preserving ovaries. [ABSTRACT FROM AUTHOR]

Published
2017

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