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Purpose: To discern whether reduced infection rates were attributed to antiseptic solutions or mechanical rectal irrigation. Patients and Methods: After receiving ethical approval, the study included patients who underwent transrectal prostate biopsy due to elevated PSA or abnormal digital rectal examination findings, and prostate cancer under active surveillance, at Tepecik Training and Research Hospital between April 2022 and June 2023. Standard antibiotic prophylaxis was administered. Patients were randomized into three equal groups according to the rectal irrigation strategy. Results: Overall complications occurred in 4%. Despite distinct cleaning agents, there was no significant difference in infection rates (p = 0.780) or fever incidence (p = 0.776). Pathological analyses revealed comparable outcomes (p = 0.764). Conclusion: The study challenges the prevailing belief that antiseptic solutions are indispensable for infection prevention, as saline demonstrated similar efficacy. Limitations include data gaps from potential external hospital visits and absent rectal microorganism swab culture. While TRUS-PB remains the gold standard, this study suggests that mechanically cleansing the rectal mucosa with saline—a cost-effective, side-effect-free alternative—may be a viable infection prevention method, particularly beneficial for patients with antiseptic allergies. The findings prompt a reconsideration of the necessity of antiseptic solutions in TRUS-PB, offering an alternative approach to mitigate infectious complications. [ABSTRACT FROM AUTHOR]

The movie "Prozac Nation" discusses Elizabeth Wurtzel's, a freshman student of the department of journalism, experience of depression, and how its process continued in different circumstances such as love, family, school, and friendship. Her parents divorced before she was 2 years old; therefore, she has already been in the psychotherapy process for long years. What she has experienced at Harvard University triggers her depression again. Elizabeth does not want to get support because of her psychotherapy experiences that she has not benefited from in the past. On the other hand, she decides to get support and starts psychotherapy due to the cognitive and behavioral processes that she presents in the face of the events she experiences due to her emotional state. Throughout this process, it is seen that Elizabeth tries to cope with depression in different ways in family, friendship, and close relationships. Elizabeth's personality and past experiences that caused her depression, her mother's parental attitudes, and cognitive and behavioral responses to the events she experienced while on treatment because of depression are discussed within the scope of the helicopter parenting, Erikson's psychosocial development stages, and Beck's depression model. [ABSTRACT FROM AUTHOR]