174 results on '"Tardito, Saverio"'
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2. Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells
3. Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer
4. Absent expansion of AXIN2+ hepatocytes and altered physiology in Axin2CreERT2 mice challenges the role of pericentral hepatocytes in homeostatic liver regeneration
5. Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia
6. Metabolic adaptations of micrometastases alter EV production to generate invasive microenvironments
7. Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
8. ALL blasts drive primary mesenchymal stromal cells to increase asparagine availability during asparaginase treatment
9. Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis
10. A map of the altered glioma metabolism
11. The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer
12. Author Correction: Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
13. Cell Culture Medium Formulation and Its Implications in Cancer Metabolism
14. Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells
15. Entry of glucose- and glutamine-derived carbons into the citric acid cycle supports early steps of HIV-1 infection in CD4 T cells
16. Physiologically relevant culture medium Plasmax improves human placental trophoblast stem cell function
17. Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells
18. Data from Activation of β-Catenin Cooperates with Loss of Pten to Drive AR-Independent Castration-Resistant Prostate Cancer
19. Supplementary Data from Activation of β-Catenin Cooperates with Loss of Pten to Drive AR-Independent Castration-Resistant Prostate Cancer
20. Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer
21. Mesenchymal stromal cells cultured in physiological conditions sustain citrate secretion with glutamate anaplerosis
22. Paraptotic Cell Death Induced by the Thioxotriazole Copper Complex A0: A New Tool to Kill Apoptosis-Resistant Cancer Cells
23. Altered metabolic landscape in IDH‐mutant gliomas affects phospholipid, energy, and oxidative stress pathways
24. PYCR1-dependent proline synthesis in cancer associated fibroblasts is required for the deposition of pro-tumorigenic extracellular matrix
25. Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis
26. Deciphering Human Glioblastoma Invasion Using a Developmental Mature Rat Brain Organoid Model
27. Glutamine stimulates mTORC1 independent of the cell content of essential amino acids
28. The non-proteinogenic amino acids l-methionine sulfoximine and dl-phosphinothricin activate mTOR
29. Polyphenon E®, a standardized green tea extract, induces endoplasmic reticulum stress, leading to death of immortalized PNT1a cells by anoikis and tumorigenic PC3 by necroptosis
30. FSMP-07. CYSTATHIONINE-Γ-LYASE DRIVES ANTIOXIDANT DEFENSE IN CYSTEINE-RESTRICTED IDH1 MUTANT ASTROCYTOMAS
31. An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism
32. Cystathionine-γ-lyase drives antioxidant defense in cysteine-restricted IDH1-mutant astrocytomas
33. Mitochondrial Metabolism Drives Triacylglycerol Synthesis to Control Regulatory T Cell Differentiation
34. Microbiome-derived carnitine mimics as novel mediators of gut-brain axis communication
35. αKG inhibits Regulatory T cell differentiation by coupling lipidome remodelling to mitochondrial metabolism
36. Microbiome-derived metabolites reproduce the mitochondrial dysfunction and decreased insulin sensitivity observed in type 2 diabetes
37. PYCR1-dependent proline synthesis in cancer-associated fibroblasts is required for the deposition of pro-tumorigenic extracellular matrix
38. Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication
39. Activation of β-Catenin Cooperates with Loss of Pten to Drive AR-Independent Castration-Resistant Prostate Cancer
40. An IDH1-Vitamin C Crosstalk Drives Human Erythroid Development By Inhibiting Pro-Oxidant Mitochondrial Metabolism
41. Synthesis, solution equilibria and antiproliferative activity of copper(II) aminomethyltriazole and aminomethylthioxotriazoline complexes
42. Gut microbiota derived mitochondrial inhibitors cross the blood brain barrier and localise white matter
43. Improving the metabolic fidelity of cancer models with a physiological cell culture medium
44. Oligodendroglioma Cells Lack Glutamine Synthetase and Are Auxotrophic for Glutamine, but Do not Depend on Glutamine Anaplerosis for Growth
45. CSIG-37. TGF-β PROMOTES MEMBRANE TUBE FORMATION IN GLIOBLASTOMA THAT CONTRIBUTES TO INVASION AND THERAPY RESISTANCE
46. Nutrient-Sensitising Drug Repurposing Screen Identifies Lomerizine As a Mitochondrial Metabolism Inhibitor in Chronic Myeloid Leukaemia
47. Cancer metabolism at a glance
48. Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma
49. Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress
50. Glucose and Glutamine Metabolism Regulate Human Hematopoietic Stem Cell Lineage Specification
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