190 results on '"Tardito, Saverio"'
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2. Rethinking our approach to cancer metabolism to deliver patient benefit
3. Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells
4. Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer
5. Absent expansion of AXIN2+ hepatocytes and altered physiology in Axin2CreERT2 mice challenges the role of pericentral hepatocytes in homeostatic liver regeneration
6. Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
7. Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis
8. Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia
9. Metabolic adaptations of micrometastases alter EV production to generate invasive microenvironments
10. ALL blasts drive primary mesenchymal stromal cells to increase asparagine availability during asparaginase treatment
11. Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis
12. A map of the altered glioma metabolism
13. An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism
14. The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer
15. Cell Culture Medium Formulation and Its Implications in Cancer Metabolism
16. Author Correction: Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
17. Entry of glucose- and glutamine-derived carbons into the citric acid cycle supports early steps of HIV-1 infection in CD4 T cells
18. Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells
19. Physiologically relevant culture medium Plasmax improves human placental trophoblast stem cell function
20. Data from Activation of β-Catenin Cooperates with Loss of Pten to Drive AR-Independent Castration-Resistant Prostate Cancer
21. Supplementary Data from Activation of β-Catenin Cooperates with Loss of Pten to Drive AR-Independent Castration-Resistant Prostate Cancer
22. Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells
23. Altered metabolic landscape in IDH‐mutant gliomas affects phospholipid, energy, and oxidative stress pathways
24. Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress
25. Glucose and Glutamine Metabolism Regulate Human Hematopoietic Stem Cell Lineage Specification
26. Paraptotic Cell Death Induced by the Thioxotriazole Copper Complex A0: A New Tool to Kill Apoptosis-Resistant Cancer Cells
27. Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer
28. Mesenchymal stromal cells cultured in physiological conditions sustain citrate secretion with glutamate anaplerosis
29. PYCR1-dependent proline synthesis in cancer associated fibroblasts is required for the deposition of pro-tumorigenic extracellular matrix
30. Deciphering Human Glioblastoma Invasion Using a Developmental Mature Rat Brain Organoid Model
31. The Thioxotriazole Copper(II) Complex A0 Induces Endoplasmic Reticulum Stress and Paraptotic Death in Human Cancer Cells
32. Glutamine stimulates mTORC1 independent of the cell content of essential amino acids
33. The non-proteinogenic amino acids l-methionine sulfoximine and dl-phosphinothricin activate mTOR
34. Nutrient-Sensitising Drug Repurposing Screen Identifies Lomerizine As a Mitochondrial Metabolism Inhibitor in Chronic Myeloid Leukaemia
35. Polyphenon E®, a standardized green tea extract, induces endoplasmic reticulum stress, leading to death of immortalized PNT1a cells by anoikis and tumorigenic PC3 by necroptosis
36. Microbiome-derived carnitine mimics as novel mediators of gut-brain axis communication
37. ALL blasts drive primary mesenchymal stromal cells to increase asparagine availability during asparaginase treatment
38. FSMP-07. CYSTATHIONINE-Γ-LYASE DRIVES ANTIOXIDANT DEFENSE IN CYSTEINE-RESTRICTED IDH1 MUTANT ASTROCYTOMAS
39. Cystathionine-γ-lyase drives antioxidant defense in cysteine-restricted IDH1-mutant astrocytomas
40. Mitochondrial Metabolism Drives Triacylglycerol Synthesis to Control Regulatory T Cell Differentiation
41. αKG inhibits Regulatory T cell differentiation by coupling lipidome remodelling to mitochondrial metabolism
42. Microbiome-derived metabolites reproduce the mitochondrial dysfunction and decreased insulin sensitivity observed in type 2 diabetes
43. PYCR1-dependent proline synthesis in cancer-associated fibroblasts is required for the deposition of pro-tumorigenic extracellular matrix
44. Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication
45. Activation of β-Catenin Cooperates with Loss of Pten to Drive AR-Independent Castration-Resistant Prostate Cancer
46. Synthesis, solution equilibria and antiproliferative activity of copper(II) aminomethyltriazole and aminomethylthioxotriazoline complexes
47. Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication
48. An IDH1-Vitamin C Crosstalk Drives Human Erythroid Development By Inhibiting Pro-Oxidant Mitochondrial Metabolism
49. Gut microbiota derived mitochondrial inhibitors cross the blood brain barrier and localise white matter
50. Improving the metabolic fidelity of cancer models with a physiological cell culture medium
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