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366 results on '"Tappe, D."'

10. Serological survey of Bartonella spp., Borrelia burgdorferi, Brucella spp., Coxiella burnetii, Francisella tularensis, Leptospira spp., Echinococcus, Hanta-, TBE- and XMR-virus infection in employees of two forestry enterprises in North Rhine–Westphalia, Germany, 2011–2013

Author

Jurke, Annette, Bannert, N., Brehm, K., Fingerle, V., Kempf, V.A.J., Kömpf, D., Lunemann, M., Mayer-Scholl, A., Niedrig, M., Nöckler, K., Scholz, H., Splettstoesser, W., Tappe, D., and Fischer, Silke F.

Published
2015
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11. Renewed risk for epidemic typhus related to war and massive population displacement, Ukraine

Author

Newton, PN, Fournier, P-E, Tappe, D, and Richards, AL

Subjects
Microbiology (medical), Infectious Diseases, Epidemiology, Pediculus, Animals, Humans, Lice Infestations, Rickettsia prowazekii, Ukraine, Typhus, Epidemic Louse-Borne
Abstract

Epidemic typhus, caused by Rickettsia prowazekii bacteria and transmitted through body lice (Pediculus humanus corporis), was a major public health threat in Eastern Europe as a consequence of World War II. In 2022, war and the resulting population displacement in Ukraine risks the return of this serious disease.

Published
2023

16. A prospective, active haemovigilance study with combined cohort analysis of 19 175 transfusions of platelet components prepared with amotosalen–UVA photochemical treatment

Author

Knutson, F., Osselaer, J., Pierelli, L., Lozano, M., Cid, J., Tardivel, R., Garraud, O., Hervig, T., Domanovic, D., Cukjati, M., Gudmundson, S., Hjalmarsdottir, I. B., Castrillo, A., Gonzalez, R., Brihante, D., Santos, M., Schlenke, P., Elliott, A., Lin, J.-S., Tappe, D., Stassinopoulos, A., Green, J., and Corash, L.

Published
2015
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19. A new host record of Haemaphysalis semermis(Acari: Ixodidae) from the domestic cat (Felis catus) (Carnivora: Felidae) in Orang Asli village, Pahang National Park Malaysia

Author

Kazim, A R, Shezryna, S, Azdayanti, M, Houssaini, J, Tappe, D, and Heo, C C

Abstract

We report the presence of a male Haemaphysalis semermiscollected from the domestic cat, Felis catusin an aboriginal village located in Pahang, Malaysia. This paper constitutes a new host record of this tick species, and also the first documentation of the infestation of companion animals other than domestic dogs (Canis lupus) by H. semermisin Malaysia. Additionally, we have included an updated host index of the tick species in Southeast Asia.

Published
2023
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27. Banding pattern indicative of echinococcosis in a commercial cysticercosis western blot

Author

Tappe D, Grüner B, Kern P, and Frosch M

Subjects
Alveolar echinococcosis, Cystic echinococcosis, Cysticercosis, Western blot, Banding pattern, Serology, Cross-reactivity, Medicine
Abstract

Abstract Objective A commercial cysticercosis Western blot was evaluated for serological cross-reactivity of sera from patients with alveolar (AE) and cystic echinococcosis (CE). Methods A total of 161 sera were examined, including 31 sera from AE-patients, 11 sera from CE-patients, 9 sera from patients with other parasitic diseases and 109 sera from patients with unrelated medical conditions. All AE-and CE-sera were also examined by the echinococcosis Western blot. Results More sera from patients with AE than with CE showed cross-reactivity in the form of ladder-like patterns ("Mikado aspect") and untypical bands at 6-8 kDa (71% and 77.4% versus 27.3% and 45.5%, respectively). In contrast, triplets of bands in the area above 50 kDa and between 24 and 39-42 kDa were more frequent in CE than in AE sera. The fuzzy band at 50-55 kDa typical for cysticercosis was absent in all AE and CE sera. Conclusions Atypical banding patterns in the cysticercosis Western blot should raise the suspicion of a metacestode infection different from Taenia solium, i.e. Echinococcus multilocularis or E. granulosus, especially when the Mikado aspect and an altered 6-8 kDa band is visible in the absence of a fuzzy 50-55 kDa band.

Published
2009
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31. Neurotropic virus infections as the cause of immediate and delayed neuropathology

Author

Ludlow, M, Kortekaas, J, Herden, C, Hoffmann, B, Tappe, D, Trebst, C, Griffin, DE, Brindle, H E, Solomon, T, Brown, AS, van Riel, Debby, Wolthers, KC, Pajkrt, D, Wohlsein, P, Martina, Byron, Baumgartner, W, Verjans, Georges, Osterhaus, ADME, and Virology

Subjects
Neuroinfectiology, Flavivirus, Virus infection, Picornavirus, Clinical Neurology, Herpesvirus, Review, Alphavirus, Rhabdovirus, Bornavirus, Pathology and Forensic Medicine, Virology & Molecular Biology, Virologie & Moleculaire Biologie, Cellular and Molecular Neuroscience, Paramyxovirus, Central nervous system, Central Nervous System Viral Diseases, Animals, Humans, Bunyavirus, Influenza virus, Neuropathology
Abstract

A wide range of viruses from different virus families in different geographical areas, may cause immediate or delayed neuropathological changes and neurological manifestations in humans and animals. Infection by neurotropic viruses as well as the resulting immune response can irreversibly disrupt the complex structural and functional architecture of the central nervous system, frequently leaving the patient or affected animal with a poor or fatal prognosis. Mechanisms that govern neuropathogenesis and immunopathogenesis of viral infections are highlighted, using examples of well-studied virus infections that are associated with these alterations in different populations throughout the world. A better understanding of the molecular, epidemiological and biological characteristics of these infections and in particular of mechanisms that underlie their clinical manifestations may be expected to provide tools for the development of more effective intervention strategies and treatment regimens. Electronic supplementary material The online version of this article (doi:10.1007/s00401-015-1511-3) contains supplementary material, which is available to authorized users.

Published
2016

32. Molecular identification of neuro-invasive helminth parasites from brain tissue: implications for prognosis, therapy, and transmission

Author

Tappe, D and Monoranu, CM

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

The definitive diagnosis of neuro-invasive helminth parasites is a challenge for both clinicians and neuropathologists. Depending on the complexity and integrity of the organisms, as well as the presentation on the tissue section plane, the correct identification of the parasites may be complicated [for full text, please go to the a.m. URL], 60th Annual Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN)

Published
2015
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33. Variegated squirrel bornavirus 1 in squirrels, Germany and the Netherlands

Author

Schlottau, K. (Kore), Jenckel, M. (Maria), Brand, J.M.A. (Judith) van den, Fast, C. (Christine), Herden, C. (Christiane), Höper, D. (Dirk), Homeier-Bachmann, T. (Timo), Thielebein, J. (Jens), Mensing, N. (Niels), Diender, B. (Bert), Hoffmann, D. (Donata), Ulrich, R.G. (Rainer), Mettenleiter, T.C. (Thomas C.), Koopmans D.V.M., M.P.G. (Marion), Tappe, D. (Dennis), Schmidt-Chanasit, J. (Jonas), Reusken, C.B.E.M. (Chantal), Beer, M. (Martin), Hoffmann, B. (Bernd), Schlottau, K. (Kore), Jenckel, M. (Maria), Brand, J.M.A. (Judith) van den, Fast, C. (Christine), Herden, C. (Christiane), Höper, D. (Dirk), Homeier-Bachmann, T. (Timo), Thielebein, J. (Jens), Mensing, N. (Niels), Diender, B. (Bert), Hoffmann, D. (Donata), Ulrich, R.G. (Rainer), Mettenleiter, T.C. (Thomas C.), Koopmans D.V.M., M.P.G. (Marion), Tappe, D. (Dennis), Schmidt-Chanasit, J. (Jonas), Reusken, C.B.E.M. (Chantal), Beer, M. (Martin), and Hoffmann, B. (Bernd)

Abstract

We screened squirrels in Germany and the Netherlands for the novel zoonotic variegated squirrel bornavirus 1 (VSBV-1). The detection of VSBV-1 in 11 squirrels indicates a considerable risk for transmission to humans handling those animals. Therefore, squirrels in contact with humans should routinely be tested for VSBV-1.

Published
2017
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34. Variegated Squirrel Bornavirus 1 in Squirrels, Germany and the Netherlands

Author

Schlottau, K, Jenckel, M, van den Brand, Judith, Fast, C, Herden, C, Hoper, D, Homeier-Bachmann, L, Thielebein, J, Mensing, N, Diender, B, Hoffmann, D, Ulrich, RG, Mettenleiter, TC, Koopmans, Marion, Tappe, D, Schmidt-Chanasit, J, Reusken, Chantal, Beer, M, Hoffmann, B, Schlottau, K, Jenckel, M, van den Brand, Judith, Fast, C, Herden, C, Hoper, D, Homeier-Bachmann, L, Thielebein, J, Mensing, N, Diender, B, Hoffmann, D, Ulrich, RG, Mettenleiter, TC, Koopmans, Marion, Tappe, D, Schmidt-Chanasit, J, Reusken, Chantal, Beer, M, and Hoffmann, B

Published
2017

35. Neurotropic virus infections as the cause of immediate and delayed neuropathology

Author

Ludlow, M. (Martin), Kortekaas, J. (Jeroen), Herden, C. (Christiane), Hoffmann, B. (Bernd), Tappe, D. (Dennis), Trebst, C. (Corinna), Griffin, D.E. (Diane E.), Brindle, H.E. (Hannah E.), Solomon, T. (Tom), Brown, A.S. (Alan S.), Riel, D.A.J. (Debby) van, Wolthers, K.C. (Katja), Pajkrt, D. (Dasja), Wohlsein, P. (Peter), Martina, B.E.E. (Byron), Baumgärtner, W. (Wolfgang), Verjans, G.M. (Georges M.), Osterhaus, A.D.M.E. (Albert), Ludlow, M. (Martin), Kortekaas, J. (Jeroen), Herden, C. (Christiane), Hoffmann, B. (Bernd), Tappe, D. (Dennis), Trebst, C. (Corinna), Griffin, D.E. (Diane E.), Brindle, H.E. (Hannah E.), Solomon, T. (Tom), Brown, A.S. (Alan S.), Riel, D.A.J. (Debby) van, Wolthers, K.C. (Katja), Pajkrt, D. (Dasja), Wohlsein, P. (Peter), Martina, B.E.E. (Byron), Baumgärtner, W. (Wolfgang), Verjans, G.M. (Georges M.), and Osterhaus, A.D.M.E. (Albert)

Abstract

A wide range of viruses from different virus families in different geographical areas, may cause immediate or delayed neuropathological changes and neurological manifestations in humans and animals. Infection by neurotropic viruses as well as the resulting immune response can irreversibly disrupt the complex structural and functional architecture of the central nervous system, frequently leaving the patient or affected animal with a poor or fatal prognosis. Mechanisms that govern neuropathogenesis and immunopathogenesis of viral infections are highlighted, using exampl

Published
2016
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38. Basal ganglia abscess due to Nocardia farcinica mimicking a malignant tumor in a patient with Wegener’s granulomatosis

Author

Johannes, S, Tappe, D, Monoranu, C, Slanina, H, Abele-Horn, M, Lee, JY, and Ernestus, RI

Subjects
brain abscess, ddc: 610, Nocardia farcinica, Wegeners's granulomatosis, 610 Medical sciences, Medicine
Abstract

Objective: Cerebral nocardiosis is rare and represents a severe infection leading to high mortality despite antibiotic therapy. We report a unique case of a brain abscess in the left basal ganglia caused by Nocardia farcinica in an immunosuppressed patient with Wegener’s granulomatosis. Method:[for full text, please go to the a.m. URL], 64. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)

Published
2013
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40. A prospective, active haemovigilance study with combined cohort analysis of 19 175 transfusions of platelet components prepared with amotosalen-UVA photochemical treatment

Author

Knutson, Folke, Osselaer, J., Pierelli, L., Lozano, M., Cid, J., Tardivel, R., Garraud, O., Hervig, T., Domanovic, D., Cukjati, M., Gudmundson, S., Hjalmarsdottir, I. B., Castrillo, A., Gonzalez, R., Brihante, D., Santos, M., Schlenke, P., Elliott, A., Lin, J. -S, Tappe, D., Stassinopoulos, A., Green, J., Corash, L., Knutson, Folke, Osselaer, J., Pierelli, L., Lozano, M., Cid, J., Tardivel, R., Garraud, O., Hervig, T., Domanovic, D., Cukjati, M., Gudmundson, S., Hjalmarsdottir, I. B., Castrillo, A., Gonzalez, R., Brihante, D., Santos, M., Schlenke, P., Elliott, A., Lin, J. -S, Tappe, D., Stassinopoulos, A., Green, J., and Corash, L.

Abstract

Background and Objectives A photochemical treatment process (PCT) utilizing amotosalen and UVA light (INTERCEPT (TM) Blood System) has been developed for inactivation of viruses, bacteria, parasites and leucocytes that can contaminate blood components intended for transfusion. The objective of this study was to further characterize the safety profile of INTERCEPT-treated platelet components (PCT-PLT) administered across a broad patient population. Materials and Methods This open-label, observational haemovigilance programme of PCT-PLT transfusions was conducted in 21 centres in 11 countries. All transfusions were monitored for adverse events within 24 h post-transfusion and for serious adverse events (SAEs) up to 7 days post-transfusion. All adverse events were assessed for severity (Grade 0-4), and causal relationship to PCT-PLT transfusion. Results Over the course of 7 years in the study centres, 4067 patients received 19 175 PCT-PLT transfusions. Adverse events were infrequent, and most were of Grade 1 severity. On a per-transfusion basis, 123 (0.6%) were classified an acute transfusion reaction (ATR) defined as an adverse event related to the transfusion. Among these ATRs, the most common were chills (77, 0.4%) and urticaria (41, 0.2%). Fourteen SAEs were reported, of which 2 were attributed to platelet transfusion (<0.1%). No case of transfusion-related acute lung injury, transfusion-associated graft-versus-host disease, transfusion-transmitted infection or death was attributed to the transfusion of PCT-PLT. Conclusion This longitudinal haemovigilance safety programme to monitor PCT-PLT transfusions demonstrated a low rate of ATRs, and a safety profile consistent with that previously reported for conventional platelet components.

Published
2015
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41. A prospective, active haemovigilance study with combined cohort analysis of 19,175 transfusions of platelet components prepared with amotosalen-UVA photochemical treatment.

Author

UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Centre de transfusion sanguine, Knutson, F, Osselaer, Jean-Claude, Pierelli, L, Lozano, M, Cid, J, Tardivel, R, Garraud, O, Hervig, T, Domanovic, D, Cukjati, M, Gudmundson, S, Hjalmarsdottir, I B, Castrillo, A, Gonzalez, R, Brihante, D, Santos, M, Schlenke, P, Elliott, A, Lin, J-S, Tappe, D, Stassinopoulos, A, Green, J, Corash, L, UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Centre de transfusion sanguine, Knutson, F, Osselaer, Jean-Claude, Pierelli, L, Lozano, M, Cid, J, Tardivel, R, Garraud, O, Hervig, T, Domanovic, D, Cukjati, M, Gudmundson, S, Hjalmarsdottir, I B, Castrillo, A, Gonzalez, R, Brihante, D, Santos, M, Schlenke, P, Elliott, A, Lin, J-S, Tappe, D, Stassinopoulos, A, Green, J, and Corash, L

Abstract

BACKGROUND AND OBJECTIVES: A photochemical treatment process (PCT) utilizing amotosalen and UVA light (INTERCEPT(™) Blood System) has been developed for inactivation of viruses, bacteria, parasites and leucocytes that can contaminate blood components intended for transfusion. The objective of this study was to further characterize the safety profile of INTERCEPT-treated platelet components (PCT-PLT) administered across a broad patient population. MATERIALS AND METHODS: This open-label, observational haemovigilance programme of PCT-PLT transfusions was conducted in 21 centres in 11 countries. All transfusions were monitored for adverse events within 24 h post-transfusion and for serious adverse events (SAEs) up to 7 days post-transfusion. All adverse events were assessed for severity (Grade 0-4), and causal relationship to PCT-PLT transfusion. RESULTS: Over the course of 7 years in the study centres, 4067 patients received 19,175 PCT-PLT transfusions. Adverse events were infrequent, and most were of Grade 1 severity. On a per-transfusion basis, 123 (0.6%) were classified an acute transfusion reaction (ATR) defined as an adverse event related to the transfusion. Among these ATRs, the most common were chills (77, 0.4%) and urticaria (41, 0.2%). Fourteen SAEs were reported, of which 2 were attributed to platelet transfusion (<0.1%). No case of transfusion-related acute lung injury, transfusion-associated graft-versus-host disease, transfusion-transmitted infection or death was attributed to the transfusion of PCT-PLT. CONCLUSION: This longitudinal haemovigilance safety programme to monitor PCT-PLT transfusions demonstrated a low rate of ATRs, and a safety profile consistent with that previously reported for conventional platelet components.

Published
2015

42. Neurotropic virus infections as the cause of immediate and delayed neuropathology

Author

Ludlow, M. (Martin), Kortekaas, J. (Jeroen), Herden, C. (Christiane), Hoffmann, B. (Bernd), Tappe, D. (Dennis), Trebst, C. (Corinna), Griffin, D.E. (Diane), Brindle, H.E. (Hannah), Solomon, T. (Tom), Brown, A.S. (Alan S.), Riel, D.A.J. (Debby) van, Wolthers, K.C. (Katja), Pajkrt, D. (Dasja), Wohlsein, P. (Peter), Martina, B.E.E. (Byron), Baumgärtner, W. (Wolfgang), Verjans, G.M.G.M. (George), Osterhaus, A.D.M.E. (Albert), Ludlow, M. (Martin), Kortekaas, J. (Jeroen), Herden, C. (Christiane), Hoffmann, B. (Bernd), Tappe, D. (Dennis), Trebst, C. (Corinna), Griffin, D.E. (Diane), Brindle, H.E. (Hannah), Solomon, T. (Tom), Brown, A.S. (Alan S.), Riel, D.A.J. (Debby) van, Wolthers, K.C. (Katja), Pajkrt, D. (Dasja), Wohlsein, P. (Peter), Martina, B.E.E. (Byron), Baumgärtner, W. (Wolfgang), Verjans, G.M.G.M. (George), and Osterhaus, A.D.M.E. (Albert)

Abstract

A wide range of viruses from different virus families in different geographical areas, may cause immediate or delay

Published
2015

45. A prospective, active haemovigilance study with combined cohort analysis of 19 175 transfusions of platelet components prepared with amotosalen–UVAphotochemical treatment

Author

Knutson, F., primary, Osselaer, J., additional, Pierelli, L., additional, Lozano, M., additional, Cid, J., additional, Tardivel, R., additional, Garraud, O., additional, Hervig, T., additional, Domanovic, D., additional, Cukjati, M., additional, Gudmundson, S., additional, Hjalmarsdottir, I. B., additional, Castrillo, A., additional, Gonzalez, R., additional, Brihante, D., additional, Santos, M., additional, Schlenke, P., additional, Elliott, A., additional, Lin, J.‐S., additional, Tappe, D., additional, Stassinopoulos, A., additional, Green, J., additional, and Corash, L., additional

Published
2015
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49. Reply to Italiano et al

Author

Esposito, D. H., primary, Rosenthal, B. M., additional, Slesak, G., additional, Tappe, D., additional, Fayer, R., additional, Bottieau, E., additional, Brown, C., additional, Grobusch, M. P., additional, Malvy, D., additional, von Sonnenburg, F., additional, Sotir, M. J., additional, Steiner, F., additional, Zanger, P., additional, and Kozarsky, P. E., additional

Published
2014
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