Search

Your search keyword '"Tanizawa, Kiminobu"' showing total 420 results
Start Over Author "Tanizawa, Kiminobu"
420 results on '"Tanizawa, Kiminobu"'

1. Subjective symptoms are triggers for the detection of immune checkpoint inhibitor-induced interstitial lung disease and associate with disease severity: a single-center retrospective study

Author

Yokoi, Mari, Yonezawa, Atsushi, Hira, Daiki, Handa, Tomohiro, Tanizawa, Kiminobu, Nakagawa, Shunsaku, Tsuda, Masahiro, Ikemi, Yasuaki, Itotani, Ryo, Yoshida, Hironori, Nomura, Motoo, Matsubara, Junichi, Murakami, Kosaku, Ozasa, Hiroaki, Muto, Manabu, and Terada, Tomohiro

Published
2024
Full Text
View/download PDF

5. Anti-interferon gamma-inducible protein 16 antibodies: Identification of a novel autoantigen in idiopathic interstitial pneumonia and its clinical characteristics based on a multicenter cohort study

Author

Sasai, Tsuneo, Nakashima, Ran, Handa, Tomohiro, Yamano, Yasuhiko, Kondo, Yasuhiro, Matsuda, Shogo, Kotani, Takuya, Tomioka, Hiromi, Tachikawa, Ryo, Tomii, Keisuke, Tanizawa, Kiminobu, Nohda, Yasuhiro, Kogame, Toshiaki, Shirakashi, Mirei, Hiwa, Ryosuke, Tsuji, Hideaki, Akizuki, Shuji, Yoshifuji, Hajime, Mimori, Tsuneyo, Kabashima, Kenji, and Morinobu, Akio

Published
2024
Full Text
View/download PDF

7. Hyperfructosemia in sleep disordered breathing: metabolome analysis of Nagahama study

Author

Nakatsuka, Yoshinari, Murase, Kimihiko, Sonomura, Kazuhiro, Tabara, Yasuharu, Nagasaki, Tadao, Hamada, Satoshi, Matsumoto, Takeshi, Minami, Takuma, Kanai, Osamu, Takeyama, Hirofumi, Sunadome, Hironobu, Takahashi, Naomi, Nakamoto, Isuzu, Tanizawa, Kiminobu, Handa, Tomohiro, Sato, Taka-Aki, Komenami, Naoko, Wakamura, Tomoko, Morita, Satoshi, Takeuchi, Osamu, Nakayama, Takeo, Hirai, Toyohiro, Kamatani, Yoichiro, Matsuda, Fumihiko, and Chin, Kazuo

Published
2023
Full Text
View/download PDF

8. Prognosis of patients with systemic sclerosis-related interstitial lung disease on the lung transplant waiting list: a retrospective study

Author

Nakayama, Yoichi, Nakashima, Ran, Handa, Tomohiro, Ohsumi, Akihiro, Yamada, Yoshito, Nakajima, Daisuke, Yutaka, Yojiro, Tanaka, Satona, Hamada, Satoshi, Ikezoe, Kohei, Tanizawa, Kiminobu, Shirakashi, Mirei, Hiwa, Ryosuke, Tsuji, Hideaki, Kitagori, Koji, Akizuki, Shuji, Yoshifuji, Hajime, Date, Hiroshi, and Morinobu, Akio

Published
2023
Full Text
View/download PDF

11. Multimodal Telemonitoring for Weight Reduction in Patients With Sleep Apnea: A Randomized Controlled Trial

Author

Murase, Kimihiko, Minami, Takuma, Hamada, Satoshi, Gozal, David, Takahashi, Naomi, Nakatsuka, Yoshinari, Takeyama, Hirofumi, Tanizawa, Kiminobu, Endo, Daisuke, Akahoshi, Toshiki, Moritsuchi, Yasutaka, Tsuda, Toru, Toyama, Yoshiro, Ohi, Motoharu, Tomita, Yasuhiro, Narui, Koji, Matsuyama, Naho, Ohdaira, Tetsuro, Kasai, Takatoshi, Tsuboi, Tomomasa, Gon, Yasuhiro, Yamashiro, Yoshihiro, Ando, Shinichi, Yoshimine, Hiroyuki, Takata, Yoshifumi, Yoshihisa, Akiomi, Tatsumi, Koichiro, Momomura, Shin-ichi, Kuroda, Tomohiro, Morita, Satoshi, Nakayama, Takeo, Hirai, Toyohiro, and Chin, Kazuo

Published
2022
Full Text
View/download PDF

12. Significance of bronchiolocentric fibrosis in patients with histopathological usual interstitial pneumonia

Author

Tanizawa, Kiminobu, Ley, Brett, Vittinghoff, Eric, Elicker, Brett M, Henry, Travis S, Wolters, Paul J, Brownell, Robert, Liu, Shuo, Collard, Harold R, and Jones, Kirk D

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Rare Diseases, Genetics, Lung, Pneumonia & Influenza, Prevention, Clinical Research, Pneumonia, Autoimmune Disease, Respiratory, Aged, Female, Genotype, Humans, Idiopathic Pulmonary Fibrosis, Kaplan-Meier Estimate, Lung Diseases, Interstitial, Male, Middle Aged, Mucin-5B, Pulmonary Fibrosis, Registries, Risk Factors, Telomere, bronchiolocentric fibrosis, idiopathic pulmonary fibrosis, usual interstitial pneumonia, Pathology, Clinical sciences, Oncology and carcinogenesis
Abstract

AimsTo evaluate the clinical significance of bronchiolocentric fibrosis (BCF) in patients with a histopathological pattern of usual interstitial pneumonia (UIP).Methods and resultsTwo hundred and fifty-two patients with pathological UIP pattern were identified. Two hundred and fifteen of these patients (215 of 252) had the multidisciplinary diagnosis of idiopathic pulmonary fibrosis (IPF). Prospectively defined clinical, radiological and pathological features (including BCF) were recorded, and peripheral blood MUC5B genotype and telomere length were measured. BCF was observed in 38% (96 of 252) of all patients and 33% (72 of 215) of IPF patients; its presence was associated with a non-IPF diagnosis on multivariate analysis (odds ratio = 3.71, 95% confidence interval = 1.68-8.19). BCF was not significantly associated with environmental exposures, gastroesophageal reflux, cigarette smoking or radiological patterns. There was no significant association of BCF with MUC5B genotype or telomere length. BCF has no significant impact on survival time.ConclusionsMost patients with BCF and a histopathological pattern of UIP have IPF. However, this combined fibrotic pattern is associated with a non-IPF multidisciplinary diagnosis, with approximately one-quarter of these patients being diagnosed as chronic hypersensitivity pneumonia or unclassifiable interstitial fibrosis. The presence of BCF in these patients is not significantly associated with presumed clinical risk factors for bronchiolocentric involvement, radiological findings, MUC5B genotype, telomere length or survival time.

Published
2019

13. Lung function decline in sarcoidosis

Author

Tanizawa, Kiminobu, Handa, Tomohiro, Nagai, Sonoko, Ikezoe, Kohei, Kubo, Takeshi, Yokomatsu, Takafumi, Ueda, Seigen, Fushimi, Yasutaka, Ogino, Shumpei, Watanabe, Kizuku, Nakatsuka, Yoshinari, Hirai, Toyohiro, and Izumi, Takateru

Published
2022
Full Text
View/download PDF

15. Anti-aminoacyl tRNA synthetase antibodies showing the discrepancy between enzyme-linked immunosorbent assay and RNA-immunoprecipitation.

Author

Sasai, Tsuneo, Ishikawa, Yuki, Nakashima, Ran, Isayama, Takuya, Tanizawa, Kiminobu, Handa, Tomohiro, Shirakashi, Mirei, Hiwa, Ryosuke, Tsuji, Hideaki, Kitagori, Koji, Akizuki, Shuji, Yoshifuji, Hajime, Mimori, Tsuneyo, and Morinobu, Akio

Subjects
ENZYME-linked immunosorbent assay, INTERSTITIAL lung diseases, OVERALL survival, WESTERN immunoblotting, DERMATOMYOSITIS
Abstract

Anti-aminoacyl-tRNA synthetase (ARS) antibodies are myositis-specific antibodies associated with anti-synthetase syndrome (ASSD). Some patients are positive for anti-ARS antibodies on enzyme-linked immunosorbent assay (ELISA) but negative on RNA-immunoprecipitation (RNA-IP) (the gold standard method). Whether these patients should be considered truly positive for anti-ARS antibodies remains unclear. Therefore, we investigated the clinical characteristics of these patients and verified the authenticity of their anti-ARS positivity. Patients who were positive for anti-ARS antibodies on ELISA were divided into the non-discrepant (positive on RNA-IP, n = 52) and discrepant (negative on RNA-IP, n = 8) groups. Patient clinical characteristics were compared between the groups. For each positive individual, the authenticity of anti-ARS antibody positivity on ELISA was cross-examined using protein-IP and western blotting. All patients in the discrepant group had lung involvement, including five (63%) with interstitial lung disease. The overall survival time was significantly lower in the discrepant group than in the non-discrepant group (p < 0.05). Validation tests confirmed the presence of anti-ARS antibodies in the sera of the discrepant group but indicated different reactivity from typical anti-ARS antibodies. In conclusion, some anti-ARS antibodies are detected by ELISA but not RNA-IP. Such anti-ARS antibody discrepancies need further elucidation to attain validation of the diagnostic process in ASSD. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

17. The impact of demographic disparities in the presentation of sarcoidosis: A multicenter prospective study

Author

Zhou, Ying, Gerke, Alicia K., Lower, Elyse E., Vizel, Alexander, Talwar, Deepak, Strambu, Irina, Francesqui, Joel, Sellares, Jacobo, Sawahata, Michiru, Obi, Ogugua Ndili, Nagai, Sonoko, Tanizawa, Kiminobu, Judson, Marc A., Jeny, Florence, Valeyre, Dominique, Cunha Castro, Marina Dornfeld, Pereira, Carlos, Balter, Meyer, and Baughman, Robert P.

Published
2021
Full Text
View/download PDF

18. Outcomes of lung transplantation for idiopathic pleuroparenchymal fibroelastosis

Author

Shiiya, Haruhiko, Nakajima, Jun, Date, Hiroshi, Chen-Yoshikawa, Toyofumi Fengshi, Tanizawa, Kiminobu, Handa, Tomohiro, Oto, Takahiro, Otani, Shinji, Shiotani, Toshio, Okada, Yoshinori, Matsuda, Yasushi, Shiraishi, Takeshi, Moroga, Toshihiko, Minami, Masato, Funaki, Soichiro, Chida, Masayuki, Yoshino, Ichiro, Hatachi, Go, Uemura, Yukari, and Sato, Masaaki

Published
2021
Full Text
View/download PDF

21. One-year lung function decline in sarcoidosis

Author

Tanizawa, Kiminobu, primary, Handa, Tomohiro, additional, Nagai, Sonoko, additional, Ikezoe, Kohei, additional, Kubo, Takeshi, additional, Yokomatsu, Takafumi, additional, Ueda, Seigen, additional, Fushimi, Yasutaka, additional, Ogino, Shumpei, additional, Hirai, Toyohiro, additional, and Izumi, Takateru, additional

Published
2024
Full Text
View/download PDF

22. Aquaporin-3 potentiates allergic airway inflammation in ovalbumin-induced murine asthma.

Author

Ikezoe, Kohei, Oga, Toru, Honda, Tetsuya, Hara-Chikuma, Mariko, Ma, Xiaojun, Tsuruyama, Tatsuaki, Uno, Kazuko, Fuchikami, Jun-Ichi, Tanizawa, Kiminobu, Handa, Tomohiro, Taguchi, Yoshio, Verkman, Alan S, Narumiya, Shuh, Mishima, Michiaki, and Chin, Kazuo

Subjects
Lymph Nodes, Spleen, CD4-Positive T-Lymphocytes, Macrophages, Alveolar, Bronchoalveolar Lavage Fluid, Animals, Mice, Inbred C57BL, Asthma, Pneumonia, Hypersensitivity, Hydrogen Peroxide, Ovalbumin, RNA, Messenger, Chemokines, Cell Count, Cell Membrane Permeability, Gene Expression Regulation, Aquaporin 3, Macrophages, Alveolar, Mice, Inbred C57BL, RNA, Messenger
Abstract

Oxidative stress plays a pivotal role in the pathogenesis of asthma. Aquaporin-3 (AQP3) is a small transmembrane water/glycerol channel that may facilitate the membrane uptake of hydrogen peroxide (H2O2). Here we report that AQP3 potentiates ovalbumin (OVA)-induced murine asthma by mediating both chemokine production from alveolar macrophages and T cell trafficking. AQP3 deficient (AQP3(-/-)) mice exhibited significantly reduced airway inflammation compared to wild-type mice. Adoptive transfer experiments showed reduced airway eosinophilic inflammation in mice receiving OVA-sensitized splenocytes from AQP3(-/-) mice compared with wild-type mice after OVA challenge, consistently with fewer CD4(+) T cells from AQP3(-/-) mice migrating to the lung than from wild-type mice. Additionally, in vivo and vitro experiments indicated that AQP3 induced the production of some chemokines such as CCL24 and CCL22 through regulating the amount of cellular H2O2 in M2 polarized alveolar macrophages. These results imply a critical role of AQP3 in asthma, and AQP3 may be a novel therapeutic target.

Published
2016

23. 胸膜肺実質線維弾性症を伴う特発性間質性肺炎および二次性間質性肺炎の肺移植症例の臨床的・画像的・病理学的特徴

Author

Ikegami, Naoya, primary, Nakajima, Naoki, additional, Yoshizawa, Akihiko, additional, Handa, Tomohiro, additional, Chen-Yoshikawa, Toyofumi, additional, Kubo, Takeshi, additional, Tanizawa, Kiminobu, additional, Ohsumi, Akihiro, additional, Yamada, Yoshito, additional, Hamaji, Masatsugu, additional, Nakajima, Daisuke, additional, Yutaka, Yojiro, additional, Tanaka, Satona, additional, Watanabe, Kizuku, additional, Nakatsuka, Yoshinari, additional, Murase, Yuko, additional, Nakanishi, Tomoko, additional, Niwamoto, Takafumi, additional, Chin, Kazuo, additional, Date, Hiroshi, additional, and Hirai, Toyohiro, additional

Published
2023
Full Text
View/download PDF

24. Comparison of chest radiological findings between coronavirus disease 2019 pneumonia and anti-melanoma differentiation-associated gene 5 antibody- positive interstitial pneumonia by artificial intelligence-based quantitative computed tomography image analysis

Author

Hamao, Nobuyoshi, primary, Ito, Isao, additional, Yamazoe, Masatoshi, additional, Hasegawa, Yoshinori, additional, Yamamoto, Shungo, additional, Emura, Masahito, additional, Endo, Kazuo, additional, Hirabayashi, Masataka, additional, Tanabe, Naoya, additional, Tanizawa, Kiminobu, additional, Handa, Tomohiro, additional, Nakashima, Ran, additional, Oi, Issei, additional, Shirata, Masahiro, additional, Nishioka, Kensuke, additional, and Hirai, Toyohiro, additional

Published
2023
Full Text
View/download PDF

25. Evaluation of Bone Mineral Density in Lung Transplant Recipients by Chest Computed Tomography

Author

Mori, Ryobu, primary, Handa, Tomohiro, additional, Ohsumi, Akihiro, additional, Ikezoe, Kohei, additional, Tanizawa, Kiminobu, additional, Uozumi, Ryuji, additional, Tanabe, Naoya, additional, Oguma, Tsuyoshi, additional, Sakamoto, Ryo, additional, Hamaji, Masatsugu, additional, Nakajima, Daisuke, additional, Yutaka, Yojiro, additional, Tanaka, Satona, additional, Yamada, Yoshito, additional, Oshima, Yohei, additional, Sato, Susumu, additional, Fukui, Motonari, additional, Date, Hiroshi, additional, and Hirai, Toyohiro, additional

Published
2023
Full Text
View/download PDF

27. Cutaneous T-cell-attracting chemokine as a novel biomarker for predicting prognosis of idiopathic pulmonary fibrosis: a prospective observational study

Author

Niwamoto, Takafumi, Handa, Tomohiro, Murase, Yuko, Nakatsuka, Yoshinari, Tanizawa, Kiminobu, Taguchi, Yoshio, Tomioka, Hiromi, Tomii, Keisuke, Kita, Hideo, Uyama, Michihiro, Tsuchiya, Michiko, Emura, Masahito, Kawamura, Tetsuji, Arai, Naoki, Arita, Machiko, Uno, Kazuko, Yoshizawa, Akihiko, Uozumi, Ryuji, Yamaguchi, Izumi, Matsuda, Fumihiko, Chin, Kazuo, and Hirai, Toyohiro

Published
2021
Full Text
View/download PDF

28. Genetic determinants of risk in autoimmune pulmonary alveolar proteinosis

Author

Sakaue, Saori, Yamaguchi, Etsuro, Inoue, Yoshikazu, Takahashi, Meiko, Hirata, Jun, Suzuki, Ken, Ito, Satoru, Arai, Toru, Hirose, Masaki, Tanino, Yoshinori, Nikaido, Takefumi, Ichiwata, Toshio, Ohkouchi, Shinya, Hirano, Taizou, Takada, Toshinori, Miyawaki, Satoru, Dofuku, Shogo, Maeda, Yuichi, Nii, Takuro, Kishikawa, Toshihiro, Ogawa, Kotaro, Masuda, Tatsuo, Yamamoto, Kenichi, Sonehara, Kyuto, Tazawa, Ryushi, Morimoto, Konosuke, Takaki, Masahiro, Konno, Satoshi, Suzuki, Masaru, Tomii, Keisuke, Nakagawa, Atsushi, Handa, Tomohiro, Tanizawa, Kiminobu, Ishii, Haruyuki, Ishida, Manabu, Kato, Toshiyuki, Takeda, Naoya, Yokomura, Koshi, Matsui, Takashi, Watanabe, Masaki, Inoue, Hiromasa, Imaizumi, Kazuyoshi, Goto, Yasuhiro, Kida, Hiroshi, Fujisawa, Tomoyuki, Suda, Takafumi, Yamada, Takashi, Satake, Yasuomi, Ibata, Hidenori, Hizawa, Nobuyuki, Mochizuki, Hideki, Kumanogoh, Atsushi, Matsuda, Fumihiko, Nakata, Koh, Hirota, Tomomitsu, Tamari, Mayumi, and Okada, Yukinori

Published
2021
Full Text
View/download PDF

31. Associations between Sleep-Disordered Breathing and Serum Uric Acid and Their Sex Differences: The Nagahama Study

Author

Sunadome, Hironobu, primary, Murase, Kimihiko, additional, Tabara, Yasuharu, additional, Matsumoto, Takeshi, additional, Minami, Takuma, additional, Kanai, Osamu, additional, Nagasaki, Tadao, additional, Takahashi, Naomi, additional, Hamada, Satoshi, additional, Tanizawa, Kiminobu, additional, Togawa, Jumpei, additional, Uiji, Sayaka, additional, Wakamura, Tomoko, additional, Komenami, Naoko, additional, Setoh, Kazuya, additional, Kawaguchi, Takahisa, additional, Morita, Satoshi, additional, Takahashi, Yoshimitsu, additional, Nakayama, Takeo, additional, Hirai, Toyohiro, additional, Sato, Susumu, additional, Matsuda, Fumihiko, additional, and Chin, Kazuo, additional

Published
2023
Full Text
View/download PDF

33. The long-term outcome of interstitial lung disease with anti-aminoacyl-tRNA synthetase antibodies

Author

Tanizawa, Kiminobu, Handa, Tomohiro, Nakashima, Ran, Kubo, Takeshi, Hosono, Yuji, Watanabe, Kizuku, Aihara, Kensaku, Ikezoe, Kohei, Sokai, Akihiko, Nakatsuka, Yoshinari, Taguchi, Yoshio, Hatta, Kazuhiro, Noma, Satoshi, Kobashi, Yoichiro, Yoshizawa, Akihiko, Oga, Toru, Hirai, Toyohiro, Chin, Kazuo, Nagai, Sonoko, Izumi, Takateru, Mimori, Tsuneyo, and Mishima, Michiaki

Published
2017
Full Text
View/download PDF

35. Evaluation of Bone Mineral Density in Lung Transplant Recipients by Chest Computed Tomography.

Author

Mori, Ryobu, Handa, Tomohiro, Ohsumi, Akihiro, Ikezoe, Kohei, Tanizawa, Kiminobu, Uozumi, Ryuji, Tanabe, Naoya, Oguma, Tsuyoshi, Sakamoto, Ryo, Hamaji, Masatsugu, Nakajima, Daisuke, Yutaka, Yojiro, Tanaka, Satona, Yamada, Yoshito, Oshima, Yohei, Sato, Susumu, Fukui, Motonari, Date, Hiroshi, and Hirai, Toyohiro

Subjects
GLUCOCORTICOIDS, CHEST X rays, SCIENTIFIC observation, DIPHOSPHONATES, LUNG transplantation, AGE distribution, PATIENTS, RETROSPECTIVE studies, OSTEOPOROSIS, SEX distribution, COMPRESSION fractures, PRE-tests & post-tests, OBSTRUCTIVE lung diseases, DESCRIPTIVE statistics, BONE density, COMPUTED tomography, SMOKING, TRANSPLANTATION of organs, tissues, etc., THORACIC vertebrae, DISEASE risk factors, DISEASE complications
Abstract

Introduction: Lung transplantation (LT) recipients are at risk of bone mineral density (BMD) loss. Pre- and post-LT BMD loss has been reported in some cross-sectional studies; however, there are limited studies regarding the serial BMD change in LT recipients. The aim of this study was to investigate the serial BMD changes and the clinical characteristics associated with BMD decline. Methods: This was a single-center, retrospective observational study. BMD was serially measured in thoracic vertebral bodies (Th4, 7, 10) using computed tomography (CT) before and 3 and 12 months after LT. The frequency of osteoporosis and factors associated with pre-LT osteoporosis and post-LT BMD loss were evaluated. The frequency of post-LT compression fracture and its associated factors were also analyzed. Results: This study included 128 adult LT recipients. LT recipients had decreased BMD (151.8 ± 42.2 mg/mL) before LT compared with age-, sex-, and smoking index-matched controls (176.2 ± 35.7 mg/mL). The diagnosis of COPD was associated with pre-LT osteoporosis. LT recipients experience further BMD decline after transplantation, and the percentage of recipients classified as exhibiting osteoporosis increased from 20% at baseline to 43% at 12 months. Recipients who had been taking no or small doses of glucocorticoids before LT had rapid BMD loss after LT. Early bisphosphonate use (within 3 months) after LT attenuated BMD loss and decreased new-onset compression fracture. Conclusion: LT recipients are at high risk for BMD loss and compression fracture after LT. Early bisphosphonate use may decrease BMD loss and compression fracture. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

36. Other iatrogenic immunodeficiency‐associated lymphoproliferative disorders in a patient with anti‐melanoma differentiation‐associated gene 5‐positive dermatomyositis: A case report and systematic literature review

Author

Nishimura, Nozomi, primary, Niwamoto, Takafumi, additional, Arai, Yasuyuki, additional, Nakashima, Ran, additional, Terada, Kazuhiro, additional, Yoshizawa, Akihiko, additional, Sakamoto, Ryo, additional, Tanizawa, Kiminobu, additional, Handa, Tomohiro, additional, Morinobu, Akio, additional, and Hirai, Toyohiro, additional

Published
2023
Full Text
View/download PDF

39. Outcome and growth of lobar graft after pediatric living-donor lobar lung transplantation

Author

Tanaka, Satona, primary, Nakajima, Daisuke, additional, Sakamoto, Ryo, additional, Oguma, Tsuyoshi, additional, Kawaguchi, Atsushi, additional, Ohsumi, Akihiro, additional, Ohata, Keiji, additional, Ueda, Satoshi, additional, Yamagishi, Hiroya, additional, Kayawake, Hidenao, additional, Yutaka, Yojiro, additional, Yamada, Yoshito, additional, Hamaji, Masatsugu, additional, Hamada, Satoshi, additional, Tanizawa, Kiminobu, additional, Handa, Tomohiro, additional, Suga, Takenori, additional, Baba, Shiro, additional, Hiramatsu, Hidefumi, additional, Ikeda, Tadashi, additional, and Date, Hiroshi, additional

Published
2022
Full Text
View/download PDF

40. Sleep disordered breathing and haemoglobin A1c levels within or over normal range and ageing or sex differences: the Nagahama study

Author

Matsumoto, Takeshi, primary, Murase, Kimihiko, additional, Tabara, Yasuharu, additional, Minami, Takuma, additional, Kanai, Osamu, additional, Takeyama, Hirofumi, additional, Sunadome, Hironobu, additional, Nagasaki, Tadao, additional, Takahashi, Naomi, additional, Nakatsuka, Yoshinari, additional, Hamada, Satoshi, additional, Handa, Tomohiro, additional, Tanizawa, Kiminobu, additional, Nakamoto, Isuzu, additional, Wakamura, Tomoko, additional, Komenami, Naoko, additional, Setoh, Kazuya, additional, Kawaguchi, Takahisa, additional, Tsutsumi, Takanobu, additional, Morita, Satoshi, additional, Takahashi, Yoshimitsu, additional, Nakayama, Takeo, additional, Sato, Susumu, additional, Hirai, Toyohiro, additional, Matsuda, Fumihiko, additional, and Chin, Kazuo, additional

Published
2022
Full Text
View/download PDF

42. Assessment of type I interferon signatures in undifferentiated inflammatory diseases: A Japanese multicenter experience

Author

Miyamoto, Takayuki, primary, Honda, Yoshitaka, additional, Izawa, Kazushi, additional, Kanazawa, Nobuo, additional, Kadowaki, Saori, additional, Ohnishi, Hidenori, additional, Fujimoto, Masakazu, additional, Kambe, Naotomo, additional, Kase, Naoya, additional, Shiba, Takeshi, additional, Nakagishi, Yasuo, additional, Akizuki, Shuji, additional, Murakami, Kosaku, additional, Bamba, Masahiro, additional, Nishida, Yutaka, additional, Inui, Ayano, additional, Fujisawa, Tomoo, additional, Nishida, Daisuke, additional, Iwata, Naomi, additional, Otsubo, Yoshikazu, additional, Ishimori, Shingo, additional, Nishikori, Momoko, additional, Tanizawa, Kiminobu, additional, Nakamura, Tomoyuki, additional, Ueda, Takeshi, additional, Ohwada, Yoko, additional, Tsuyusaki, Yu, additional, Shimizu, Masaki, additional, Ebato, Takasuke, additional, Iwao, Kousho, additional, Kubo, Akiharu, additional, Kawai, Toshinao, additional, Matsubayashi, Tadashi, additional, Miyazaki, Tatsuhiko, additional, Kanayama, Tomohiro, additional, Nishitani-Isa, Masahiko, additional, Nihira, Hiroshi, additional, Abe, Junya, additional, Tanaka, Takayuki, additional, Hiejima, Eitaro, additional, Okada, Satoshi, additional, Ohara, Osamu, additional, Saito, Megumu K., additional, Takita, Junko, additional, Nishikomori, Ryuta, additional, and Yasumi, Takahiro, additional

Published
2022
Full Text
View/download PDF

46. Sleep disordered breathing and haemoglobin A1c levels within or over normal range and ageing or sex differences: the Nagahama study.

Author

Matsumoto, Takeshi, Murase, Kimihiko, Tabara, Yasuharu, Minami, Takuma, Kanai, Osamu, Takeyama, Hirofumi, Sunadome, Hironobu, Nagasaki, Tadao, Takahashi, Naomi, Nakatsuka, Yoshinari, Hamada, Satoshi, Handa, Tomohiro, Tanizawa, Kiminobu, Nakamoto, Isuzu, Wakamura, Tomoko, Komenami, Naoko, Setoh, Kazuya, Kawaguchi, Takahisa, Tsutsumi, Takanobu, and Morita, Satoshi

Subjects
AGE differences, SLEEP disorders, SLEEP apnea syndromes, SLEEP duration, PULSE oximeters, SLEEP interruptions, AGE
Abstract

Summary: Recently an association between blood glucose dysregulation and sleep disruption was suggested. The association between sleep disordered breathing, most of which is due to obstructive sleep apnea (OSA) in the general population, and diabetic severity, as well as the impact of antidiabetic treatment, remains unclear. This study aimed to investigate these associations as well as age and sex differences. This cross‐sectional study evaluated 7,680 community participants as the main cohort (population‐based cohort). OSA was assessed by the 3% oxygen desaturation index from pulse oximetry, which was corrected for sleep duration obtained by wrist actigraphy. For arguing the limitations for using pulse oximetry, 597 hospitalised patients, who were assessed by the apnea–hypopnea index from attended polysomnography, were also evaluated as the validation cohort (hospital‐based cohort). Moderate‐to‐severe OSA was more prevalent as haemoglobin A1c (HbA1c) levels increased (<5.6%/5.6%–<6.5%/6.5%–<7.5%/≥7.5%, respectively) in both cohorts (p < 0.001), but only in those without antidiabetic treatment. The HbA1c level was an independent factor for moderate‐to‐severe OSA (population‐based cohort, odds ratio [OR] 1.26, 95% confidence interval [CI] 1.10–1.45; hospital‐based cohort, OR 1.69, 95% CI 1.22–2.33, per 1% increase). These associations were more prominent in the middle‐aged (aged <60 years) than in the elderly (aged ≥60 years) and in women than in men in both cohorts. The prevalence of moderate‐to‐severe OSA in patients with antidiabetic treatment in the hospital‐based cohort was ≥75% regardless of HbA1c levels. In conclusion, an association between the prevalence of OSA and HbA1c level even within or over the normal range was found only in patients without antidiabetic treatment and was more prominent in the middle‐aged and in women. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

47. Clinical significance of radiological pleuroparenchymal fibroelastosis pattern in interstitial lung disease patients registered for lung transplantation: a retrospective cohort study

Author

Tanizawa, Kiminobu, Handa, Tomohiro, Kubo, Takeshi, Chen-Yoshikawa, Toyofumi F., Aoyama, Akihiro, Motoyama, Hideki, Hijiya, Kyoko, Yoshizawa, Akihiko, Oshima, Yohei, Ikezoe, Kohei, Tokuda, Shinsaku, Nakatsuka, Yoshinari, Murase, Yuko, Nagai, Sonoko, Muro, Shigeo, Oga, Toru, Chin, Kazuo, Hirai, Toyohiro, and Date, Hiroshi

Published
2018
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results