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5. Development of an application tool to support returnees in Fukushima

Author

Ohba, T., Goto, A., Nakano, H., Nollet, K.E., Murakami, M., Koyama, Y., Honda, K., Yoshida, K., Yumiya, Y., Kuroda, Y., Kumagai, A., Ohira, T., Tanigawa, K., Atsushi, Kumagai, Ohba, T., Goto, A., Nakano, H., Nollet, K.E., Murakami, M., Koyama, Y., Honda, K., Yoshida, K., Yumiya, Y., Kuroda, Y., Kumagai, A., Ohira, T., Tanigawa, K., and Atsushi, Kumagai

Abstract

To promote radiation protection and health promotion among returning residents (returnees) in coastal areas of Fukushima, eHealth principles were used to develop a new application tool (app) that can record radiation exposure and health status while providing comprehensive support to returnees. Intended users are returnees and health and welfare workers. After assessing their needs, a flowchart and prototype for operational logic were created using commercially available software tools. Professional developers will focus on improving the user interface and ensuring data security. The finished app will be compatible with mobile telephones and tablets. Utility and ease of use are paramount to serve returnees of all ages effectively.

Published
2022

9. Development of an application tool to support returnees in Fukushima

Author

Ohba, T., primary, Goto, A., additional, Nakano, H., additional, Nollet, K.E., additional, Murakami, M., additional, Koyama, Y., additional, Honda, K., additional, Yoshida, K., additional, Yumiya, Y., additional, Kuroda, Y., additional, Kumagai, A., additional, Ohira, T., additional, and Tanigawa, K., additional

Published
2021
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12. 福島における帰還住民を支援するためのアプリケーションツールの開発

Author

Ohba, T., Goto, A., Nakano, H., Nollet, K.E., Murakami, M., Koyama, Y., Honda, K., Yoshida, K., Yumiya, Y., Kuroda, Y., Atsushi, Kumagai, Ohira, T., and Tanigawa, K.

Abstract

To promote radiation protection and health promotion among returning residents (returnees) in coastal areas of Fukushima, we are applying eHealth principles to develop a new app that can record radiation exposure and health status while providing comprehensive support to returnees. Intended users are returnees and health and welfare workers. After assessing their needs, we flowcharted the app and prototyped its operational logic with commercially available software tools. Professional developers will focus on improving the user interface and ensuring data security. The finished app will be compatible with mobile phones and tablets. To effectively serve elderly and child-rearing generations of returnees, utility and ease-of-use are paramount., ICRP International Conference on Recovery After Nuclear Accidents Radiological Protection Lessons from Fukushima and Beyond

Published
2020

13. Implementing eHealth with radiation records: a new support package for evacuees returning to areas around the Fukushima Daiichi nuclear power station

Author

Ohba, T., Goto, A., Nakano, H., Nollet, K.E., Murakami, M., Yoshida, K., Yumiya, Y., Honda, K., Kuroda, Y., Atsushi, Kumagai, Ohira, T., Tanigawa, K., Ohba, T., Goto, A., Nakano, H., Nollet, K.E., Murakami, M., Yoshida, K., Yumiya, Y., Honda, K., Kuroda, Y., Atsushi, Kumagai, Ohira, T., and Tanigawa, K.

Abstract

Following the 2011 Fukushima Daiichi nuclear power station (FDNPS) accident, numerous initiatives emerged to address the needs of evacuees, including those eligible to return home. These came from multiple channels, timely in many cases, but in retrospect, needing better coordination. By embracing eHealth, we are attempting to coordinate efforts in Fukushima intended to link returnees with health information and care providers, not only for radiological protection in particular, but also for health promotion in general. We aim to establish a comprehensive support system for residents in municipalities around the FDNPS by developing a digital application for interactive communication regarding radiation and health promotion and to link the tool to other resources provided by local health care providers and radiation specialists. This paper explains the progress of our innovative trial to introducing eHealth in areas affected by the FDNPS accident. Based on international recommendations for developing a digital tool in response to a nuclear accident, we designed a comprehensive support package including development and implementation of the application, data management, and health counselling and ethical considerations arising from such outreach. Our trial of connecting disaster-affected citizens to health services using informatics could serve as a model eHealth program for long-term restoration after a nuclear accident.

Published
2020

18. Mobile apps for environmental and health monitoring after a nuclear accident: Towards a better resilience with involvement of citizen science and general public

Author

Liutsko, L., primary, Fattibene, P., additional, Della Monaca, S., additional, De Angelis, C., additional, Brescianini, S., additional, Nuccetelli, C., additional, Ohba, T., additional, Goto, A., additional, Lyamzina, Y., additional, Sarukhan, A., additional, Tanigawa, K., additional, Deborah Oughton, D., additional, Tomkiv, Y., additional, Laurier, D., additional, Bottolier-Depois, J., additional, Charron, S., additional, Croüail, P., additional, Shneider, T., additional, Maître, M., additional, Pirard, P., additional, Van Nieuwenhuyse, A., additional, Novikava, N., additional, Cardis, V., additional, Barquinero, J., additional, and Cardis, E., additional

Published
2020
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24. Abstracts of selected papers presented at the 33rd annual meeting of the japanese society of gastroenterology

Author

Fujii, Daigo, Suyama, Masafumi, Sugiyama, Masanori, Atomi, Yutaka, Inui, Kazuo, Nakazawa, Saburo, Nakajima, Kimihiro, Katoh, Hiroyuki, Kaneda, Makoto, Ogura, Yoshifumi, Eto, Toshifumi, Tsunoda, Tsukasa, Uchimura, Masayuki, Narita, Kazuyuki, Sugioka, Atsushi, Tsuzuki, Toshiharu, Kanemitsu, Keiichiro, Tashiro, Seiki, Yoshikawa, Tatsuya, Hanyu, Fujio, Kondo, Satoshi, Nimura, Yuji, Eriguchi, Naofumi, Nakayama, Toshimichi, Mitake, Masahiro, Naitoh, Yasuo, Isawa, T., Okamoto, A., Miyazaki, Hiroshi, Ogata, Yoshirou, Kuno, Nobuyoshi, Kurimoto, Kumiko, Noguchi, Tohru, Makuuchi, Masatoshi, Ikari, Takaaki, Ariyama, Joe, Takao, Sonshin, Shimazu, Hisaaki, Kobari, Masao, Matsuno, Seiki, Tanigawa, K., Mizumoto, R., Nakasako, T., Hanyu, F., Saito, Naoyuki, Hiraoka, Takehisa, Ishikawa, Osamu, Imaoka, Shingi, Miyazaki, Naoyuki, Saitoh, Yoichi, Harada, Akio, Takagi, Hiroshi, Kawai, Y., Yamamoto, S., Nakanishi, Ryo, Beppu, Tomoe, Okushiba, Shunichi, Katoh, Hiroyuki, Sakamoto, Hiroaki, Obara, Katsutoshi, Toba, Masahito, Onda, Masahiko, Azuma, Masayoshi, Kashiwagi, Toru, Sumino, Michihiro, Toyonaga, Atsushi, Hagiwara, Masaru, Sakai, Masahiro, Kokubu, Shigehiro, Shibata, Hisao, Miyoshi, Hirofumi, Orino, Shinya, Yoshida, Tomoharu, Itoh, Tadahiko, Murashima, Naoya, Matsumura, Masahiko, Tsujii, Tadasu, Murayama, Takashi, Tameda, Yukihiko, Matsutani, Shoichi, Ishii, Hiroshi, Mitarai, Yoshinobu, Kobayashi, Michio, Nishida, Hitoshi, Kawada, Taiji, Matsuda, Hiroko, Kawasaki, Tsunehisa, Arakawa, Tetsuo, Kobayashi, Kenzo, Ota, Shinichi, Terano, Akira, Nakamura, Masahiko, Oda, Masaya, Tari, Akira, Yamamoto, Goso, Saito, Eiichi, Matsuo, Yutaka, Mizuno, Motowo, Tomoda, Jun, Asada, Shuji, Takiuchi, Hiroya, Mogi, Mizuhiro, Kitajima, Masaki, Nagano, Kouichi, Sato, Nobuhiro, Naito, Yuji, Yoshikawa, Toshikazu, Asaka, Masahiro, Sato, Yasuo, Iwafuchi, Mitsuya, Watanabe, Hidenobu, Yoshida, Yukio, Kihira, Ken, Kashiwagi, Hideyuki, Aoki, Teruaki, Nishikawa, Masahiro, Suzuki, Takashi, Matsui, Toshiyuki, Iida, Mitsuo, Katoh, H., Munakata, A., Itsuno, Minoru, Makiyama, Kazuya, Hibi, Toshifumi, Kitahora, Tetsuji, Igarashi, Masahiro, Katsumata, Tomoe, Satomi, Masamichi, Yamamura, Makoto, Hirata, Ichiro, Slezak, Premysl, Kubota, Yoshiro, Muto, Tetsuichiro, Morise, Kimitomo, Kusugami, Kazuo, Sugita, Akira, Fukushima, Tsuneo, Okada, Mitsuo, Sakurai, Toshihiro, Iida, Mitsuo, Kawasaki, Atsushi, Hiwatashi, Nobuo, Yamazaki, Hideo, Oriishi, Tetsuharu, Sasaki, Ei, Takazoe, Masakazu, Inoue, Noboru, Funayama, Y., and Matsuno, S.

Published
1993
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30. Electrical characteristics of spiral coil planar inductors using amorphous alloy ribbons as magnetic layers

Author

Tanigawa, K., Hirano, H., Sato, T., and Tanaka, N.

Subjects
Inductors -- Design and construction, Iron alloys -- Analysis, Physics
Abstract

Planar inductors with thick Fe-based amorphous alloy ribbons as magnetic layers effectively reduce the volume of switching converters. The ribbon thickness increases dc current and saturation value required to reduce the volume with high magnetic energy from the Fe-alloy component.

Published
1994

31. Ultra-low-frequency self-oscillation of photocurrent in InxGa1–xAs/Al0.15Ga0.85As multiple-quantum-well p–i–n diodes

Author

Kyushu Institute or Technology, Tobata, Kitakyushu 804-8550, Japan, Kwansei Gakuin University, Nishinomiya 662-0891, Japan, Satake, A., Tanigawa, K., Kimura, T., Fujiwara, K., Sano, N., Kyushu Institute or Technology, Tobata, Kitakyushu 804-8550, Japan, Kwansei Gakuin University, Nishinomiya 662-0891, Japan, Satake, A., Tanigawa, K., Kimura, T., Fujiwara, K., and Sano, N.

Abstract

type:Journal Article, We report an observation of ultra-low-frequency self-oscillation of photocurrent in InxGa1–xAs/Al0.15Ga0.85As multiple-quantum-well p–i–n diodes. The photocurrent intensity shows self-oscillations with a characteristic frequency of ~0.1 Hz at low temperatures under reverse bias voltages. The photocurrent self-oscillation depends on applied bias voltage, temperature, illumination power, and indium content of quantum-well layers. These dependences indicate that the photocurrent self-oscillation is attributed to photogenerated carriers trapped in localized centers within InxGa1–xAs quantum-well regions., source:http://dx.doi.org/10.1063/1.1806268, source:http://www.aip.org

Published
2017

32. Ultra-low frequency photocurrent self-oscillation in strained InxGa1-xAs quantum well diodes

Author

Tanigawa, K, Fujiwara, Kenzo, and Sano, N

Subjects
Self-oscillation, III–V semiconductor, Photocurrent, Quantum well
Abstract

Ultra-low frequency photocurrent (PC) self-oscillation has been investigated in aIn0.15Ga0.85As/Al0.15Ga0.85As quantum-well (QW) diode in details as a function of temperature,excitation power and wavelength. The PC oscillation frequency increases with increasing temperatureand illumination power at excitation wavelengths below the leading n = 1 heavy-hole excitonresonance line under reverse bias conditions. The illumination wavelength dependence shows a clearevidence for beating due to two oscillators when photoexcitation by shorter wavelength below 1050nm is used. These results suggest that the low-frequency PC self-oscillation with a characteristicfrequency of about 0.01-0.1 Hz is caused by oscillating electric fields due to two-types ofphotogenerated charge carriers trapped at deep localized centers within the QW regions.

Published
2007

34. General lectures (II)

Author

Segawa, K., Nakazawa, S., Koide, N., Imai, K., Matsuo, N., Yamamoto, Y., Shiobara, M., Shimada, H., Kawai, K., Machida, K., Okabe, N., Hoshi, Y., Koizumi, Y., Watanuki, T., Hiroshima, Y., Matsusaka, Y., Katase, K., Sakuma, Y., Matoba, N., Murata, N., Toyama, Y., Murai, S., Nukaga, A., Ishimatsu, N., Watanabe, Y., Abe, M., Ono, Y., Hirai, K., Iwabuchi, S., Suzuki, K., Aoki, T., Masamura, K., Yoshida, K., Ikeuchi, J., Nagao, F., Kobayashi, A., Toriie, S., Nakajima, M., Kohli, M., Ida, K., Kawai, K., Masuda, M., Hattori, T., Fujita, S., Tamada, T., Inoue, K., Usui, T., Yamaya, S., Ohtsuka, K., Shiraki, Y., Fujishima, S., Tochikubo, O., Miyamoto, S., Ueda, A., Asano, K., Kunisada, M., Miyake, H., Fujii, Y., Yoshimoto, S., Hiramatsu, K., Nakano, S., Takeda, T., Kitamura, K., Horiguchi, Y., Okada, K., Okada, M., Kuwabara, T., Tanaka, M., Konno, K., Hattori, T., Isobe, K., Iwasaki, A., Unoura, T., Matsumoto, M., Yoshida, T., Takahashi, I., Abe, M., Maeda, H., Hayashi, T., Koizumi, H., Iwasaki, M., Takahashi, K., Honda, T., Ariga, K., Mohri, S., Suga, Y., Ono, T., Kobayashi, K., Mizuno, T., Sameshima, Y., Shiozaki, Y., Sasakawa, M., Hiramatsu, A., Ikehara, K., Nagata, T., Tatsumi, K., Abe, M., Aoki, M., Iwasaki, S., Aizawa, T., Kajiwara, K., Sata, K., Omata, S., Imamura, K., Kondo, K., Sajima, H., Sato, Y., Kiryu, H., Mimoto, S., Masuoka, T., Kira, K., Mizumoto, R., Kuratsuka, H., Honjo, I., Hojo, Y., Nakajima, H., Tosaka, T., Arai, O., Kobayashi, N., Obata, N., Ito, S., Takaoka, T., Uragami, Y., Kitamura, Y., Kishi, S., Fujii, S., Okuda, H., Hirano, K., Kano, H., Ogino, M., Ueda, Y., Nishiwaki, K., Iwamura, N., Aoki, T., Hiramatsu, K., Kamada, T., Suematsu, T., Fusamoto, H., Okuda, H., Abe, H., Katayama, S., Yamaguchi, K., Fukuda, M., Ishii, T., Kaito, I., Sato, S., Sasaki, H., Onodera, H., Yamanaka, M., Akagi, K., Miyazaki, S., Okumura, M., Omae, T., Nakamura, Y., Wada, M., Nakai, Y., Inoue, S., Arima, T., Yamasaki, S., Takano, T., Katsuta, Y., Yano, T., Isoda, K., Aramaki, T., Fukuda, N., Ichikawa, T., Okumura, H., Adachi, Y., Inoue, R., Iwasaki, Y., Tanaka, S., Yamamoto, T., Wakisaka, G., Nakaya, H., Takase, S., Ikegami, F., Takada, A., Kobayashi, K., Takeuchi, J., Kato, Y., Funayama, A., Kakumu, S., Ito, S., Okuyama, S., Taoka, Y., Endo, T., Chizuka, R., Yanagida, T., Chizuka, S., Usui, H., Ando, T., Takai, T., Wakahara, T., Kojima, M., Fukazawa, T., Takahashi, Y., Miyamura, S., Urakawa, T., Shima, T., Miyaji, K., Okazaki, T., Kashimura, S., Koyama, K., Yamauchi, H., Matsuo, Y., Takagi, Y., Muto, I., Owada, Y., Otowa, T., Sato, T., Naito, C., Okada, K., Sugawara, K., Nokiba, T., Fujii, Y., Kido, H., Sasaki, M., Sugai, Y., Nishimura, G., Nanbu, H., Kamiyama, Y., Yamada, T., Yamaoka, Y., Takeda, H., Ohsawa, T., Kamano, T., Mizukami, T., Kitamura, O., Ozawa, K., Takasan, H., Honjo, I., Miyasaki, R., Katayama, T., Amakawa, T., Hirose, K., Furukawa, Y., Noguchi, M., Okamoto, M., Maezawa, H., Tanaka, N., Yamada, S., Hisata, T., Hata, C., Sawa, J., Kato, Y., Mituda, Y., Oohira, S., Hayasaka, A., Okuyama, T., Fukui, S., Takeda, T., Furuichi, T., Yamamitsu, S., Yamauchi, K., Konishi, Y., Maeda, S., Setoyama, S., Otsuji, S., Ibata, T., Niu, H., Ogawa, A., Tujioka, E., Maeda, T., Takewa, M., Matumoto, T., Tamada, K., Maeda, A., Sumita, H., Iseki, Y., Yukawa, S., Nitta, Y., Isida, K., Nomoto, H., Setoyama, S., Maeda, S., Otsuji, S., Sato, R., Sato, G., Toyokawa, S., Yamamoto, G., Ohtomi, S., Haga, M., Ueno, Y., Fukuda, M., Endo, R., Yokota, T., Ohsawa, J., Kohno, A., Ohtoshi, E., Yasugi, H., Ichikawa, H., Mizumoto, R., Honjo, I., Ando, K., Suzuki, H., Nishiwaki, T., Kishimoto, T., Miki, T., Takeshige, K., Sawada, M., Hidemura, R., Yamamoto, S., Itoh, S., Kashiwagi, T., Kishida, M., Imamura, O., Suematus, T., Kamada, T., Sakoda, K., Kawada, T., Arima, Y., Kamimura, T., Takesue, M., Katsuki, T., Akita, H., Yakeishi, Y., Takehisa, I., Miyasato, K., Yoshida, H., Hidemura, R., Kubota, K., Aoki, S., Suzuki, S., Kishimoto, T., Miyahara, T., Ando, K., Nishiwaki, T., Miki, T., Takeshige, K., Sawada, M., Itoh, S., Yamamoto, S., Fujiwara, K., Sakai, T., Oda, T., Igarashi, S., Fukuhara, M., Tsujii, T., Tamura, T., Matsuoka, Y., Takahashi, H., Sakamoto, T., Fukuda, S., Oku, M., Matsui, T., Morita, T., Oyazato, Y., Kimura, K., Moriya, W., Fukui, S., Suzuki, K., Morimoto, S., Tsuiki, S., Shoji, K., Nakai, Y., Hata, M., Kubo, J., Yoshizawa, K., Nagayama, K., Ozawa, Y., Yoshida, M., Horiguchi, M., Machii, A., Nitta, Y., Aiso, Y., Kitahara, N., Kitazawa, E., Fukuda, K., Saiti, N., Murakami, Y., Nao, Y., Okazaki, I., Funatsu, K., Maruyama, K., Takagi, B., Yasuraoka, S., Ishii, K., Matsuzaki, S., Takahashi, H., Ishii, H., Kamegaya, K., Sambe, K., Ishikawa, H., Tajima, Y., Kuroda, A., Ishihara, Y., Sato, N., Ishikawa, I., Noro, T., Kakumoto, Y., Mekjian, H. S., Thomford, N. R., Yokomura, T., Adachi, S., Yamamoto, A., Saito, I., Kawamura, A., Miyata, M., Kasai, S., Kawanishi, N., Tamaki, A., Mito, M., Kasai, Y., Hasumi, A., Uchiyama, T., Tachikawa, Y., Takanashi, T., Kanke, T., Matsuda, K., Takanashi, T., Kanke, T., Matsuda, K., Hamana, G., Sakuma, M., Sugita, T., Tomita, K., Yamasaki, S., Tsuzuki, T., Uekusa, M., Matsuzaki, M., Takagi, B., Tsuchiya, M., Uchimura, M., Murohisa, T., Muto, Y., Ishigaki, J., Waki, S., Tsuchiya, R., Sho, M., Furukawa, M., Suzuki, N., Nagashima, H., Matsushiro, T., Saitoh, T., Nakamura, N., Hatanaka, T., Kobayashi, N., Nakamura, Y., Sato, T., Tooi, K., Tanaka, Y., Kadokura, N., Okada, Y., Yanakgi, I., Tanaka, N., Sekiya, V. M., Adachi, K., Miyashita, M., Moriyama, Y., Onda, M., Yoshioka, M., Teraoka, T., Shimizu, Y., Fujishima, G., Ookawa, K., Miki, M., Shirota, A., Aihara, K., Shiga, T., Sano, H., Hayashi, S., Hori, M., Sato, H., Chuman, Y., Tsukase, S., Nakahara, N., Ehira, S., Setoyama, S., Nishimata, H., Irisa, T., Tokutome, K., Nakashima, Y., Koga, H., Yokoyama, H., Otsuji, T., Chujo, Y., Yamamoto, T., Gotoda, S., Uchiyama, S., Kosaki, G., Ohkura, H., Mukojima, T., Hattori, N., Sasaki, O., Soejima, K., Inokuchi, K., Utsunomiya, J., Maki, T., Iwama, T., Matsunaga, Y., Shimomura, T., Nakajima, T., Ichikawa, S., Miyanaga, T., Sengoku, K., Hamaguchi, E., Aoki, N., Nomura, T., Matsuoka, A., Suzuki, N., Nagahama, A., Kazumi, T., Miyawaki, H., Sakamoto, T., Miyasaki, K., Kato, K., Miyazaki, Y., Harada, N., Yamada, K., Tashiro, S., Sakai, K., Ho, N., Murayama, H., Yada, M., Sakabe, T., Shimizu, H., Kuroki, M., Nishida, S., Kato, K., Ishiyama, S., Yukawa, K., Hayashi, M., Soh, K., Doi, K., Fukuda, M., Nakagawa, A., Yukawa, E., Uematsu, Y., Nara, K., Hattori, H., Watanabe, M., Yoshida, H., Sato, K., Okuse, S., Sato, K., Murotani, T., Takasu, S., Konta, M., Uchiya, T., Fujimaki, N., Yoshida, K., Yoshikawa, K., Uchida, M., Nakamura, N., Nagao, F., Kawana, S., Tamura, K., Hashimoto, T., Kobayashi, K., Hara, T., Nosaka, J., Fukui, O., Inaba, E., Otsukasa, S., Sanada, K., Hiraide, H., Senyo, G., Ootani, A., Nakayama, T., Takei, S., Miki, H., Tanaka, M., Minota, S., Nakayama, K., Nakagawa, K., Shiraishi, T., Kawauchi, H., Nagaya, H., Mizushima, K., Tachimi, Y., Namiki, M., Masuda, K., Mitsutani, N., Mukuta, T., Koizumi, T., Takeuchi, T., Nemoto, T., Takabayashi, H., Takagi, M., Hongo, Y., Kojima, H., Nishimura, M., Hino, S., Hirayama, J., Nakamura, M., Irisa, T., Koga, S., Hirayama, C., Kikuch, S., Ito, M., Hidano, S., Ooya, T., Banno, H., Tomura, A., Kato, K., Koyama, T., Takei, T., Tomimura, T., Yamauchi, M., Kobayashi, K., Nakaya, Y., Takase, S., Kato, Y., Takeuchi, J., Ikegami, F., Matsuda, Y., Takada, A., Udo, K., Kojima, M., Hukuda, N., Kametani, M., Miyagawa, T., Wakahara, T., Takahashi, Y., Imaeda, T., Senda, K., Fujita, S., Okubo, H., Kanoda, K., Miyashita, B., Ishizuka, H., Goto, T., Oto, K., Kaneda, H., Hase, M., Matsuda, J., Kawai, T., Ikehara, H., Baba, S., Ishii, M., Tozawa, T., Inoue, E., Mizuno, N., Saeki, S., Nakaji, T., Narabayashi, T., Okuno, T., Yamada, H., Tanno, M., Chiba, K., Iio, M., Shibata, K., Furuhashi, F., Mizuochi, K., Ohashi, S., Kato, K., Nakano, M., Otsuka, S., Irie, M., Akima, M., Maruyama, Y., Oyamada, F., Nagata, E., Kubo, Y., Arishima, T., Otsuyama, Y., Kaneto, A., Shimogawa, Y., Tanigawa, K., Okabe, N., Nakajima, K., Onishi, S., Kasahara, A., Shimizu, T., Ikehara, Y., Tajima, H., Okamoto, A., Komibuchi, T., Negoro, T., Nihonsugi, A., Ishii, M., Tozawa, T., Ogawa, Y., Otani, H., Ishida, M., Yashima, H., Shoji, K., Tsuiki, S., Morimoto, S., Nakai, Y., Ryo, M., Ozawa, Y., Tanaka, T., Horiguchi, M., Taketa, K., Watanabe, A., Yumoto, Y., Tanaka, A., Takesue, A., Aoe, H., Ueda, M., Shimamura, J., Kosaka, K., Kashiwara, E., Orita, K., Konaga, E., Suzuki, K., Tanaka, S., Kaneda, S., Ogawa, K., Tamura, H., Okanishi, S., Ueda, T., Horie, H., Kamachi, M., Asihara, T., Daido, R., Izumi, T., Kurihara, M., Sumida, M., Haraikawa, M., Hayakawa, H., Shirakabe, H., Yasui, A., Noguchi, M., Okamoto, M., Furukawa, Y., Miyasaki, R., Hirose, K., Katayama, T., and Maezawa, H.

Published
1974
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35. Phosphoinositide Hydrolysis and Insulin Release in Fetal Rat Islets

Author

Lewis Nj and Tanigawa K

Subjects
endocrine system, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Biology, Phosphatidylinositols, Rats, Sprague-Dawley, Islets of Langerhans, chemistry.chemical_compound, Fetus, Endocrinology, Culture Techniques, Internal medicine, Insulin Secretion, Internal Medicine, medicine, Animals, Insulin, Inositol, Pancreatic hormone, geography, geography.geographical_feature_category, Hepatology, Hydrolysis, Islet, Rats, medicine.anatomical_structure, chemistry, Cell culture, Efflux, Pancreas
Abstract

The association between phosphoinositide hydrolysis and insulin release in fetal islets was investigated. Islets from 21.5-day-old fetal rats were cultured for 7 days in inositol-free RPMI 1640 containing 11.1 mM glucose and labeled with 20 microCi/ml [3H]inositol for the final 2 days. The labeled islets were then perifused under various conditions for 60 min. Glucose (16.7 mM) caused a modest increase in [3H] efflux from labeled islets, but there was a subsequent fall-off in [3H] efflux. Fetal islets showed the first phase of insulin release without the continued rising second phase. When islets were perifused with 5 mM LiCl, the glucose-induced efflux of [3H] was greatly reduced, whereas glucose-induced insulin release was not affected. A pronounced effect of LiCl was an increase in inositol monophosphate, indicating increased phospholipase C activity. Although marked release of [3H] from labeled islets occurred in the presence of 5 mM inositol, the decreases in radioactive inositol lipid and insulin release induced by glucose were not changed. These data suggest that the fall-off in the second phase of insulin release from fetal islets may be partly due to blunted phosphoinositide hydrolysis.

Published
1994

42. PP219-SUN ASSOCIATION BETWEEN SERUM PREALBUMIN LEVELS AND CALORIC INTAKE IN CRITICAL ILL PATIENTS PROVIDED ENTERAL NUTRITION ALONG SCCM/ASPEN RECOMMENDATIONS FOR CALORIC NEEDS

Author

Iwasaki, Y., primary, Yamane, M., additional, Une, K., additional, Otani, T., additional, Ota, K., additional, Tamura, T., additional, Itai, J., additional, Kida, Y., additional, Suzuki, K., additional, Koyama, K., additional, Torikoshi, Y., additional, Hirohashi, N., additional, Tazuma, S., additional, and Tanigawa, K., additional

Published
2012
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49. Nitric oxide metabolism in canine sepsis: Relation to regional blood flow

Author

Tanigawa, K, Bellomo, R, Kellum, JA, Kim, YM, Zar, H, Lancaster, JR, Pinsky, MR, Ondulick, B, Tanigawa, K, Bellomo, R, Kellum, JA, Kim, YM, Zar, H, Lancaster, JR, Pinsky, MR, and Ondulick, B

Abstract

Purpose: To investigate the role of nitric oxide (NO) in early endotoxemia on the systemic and regional blood flow by measuring the plasma nitrite/nitrate (NOx) and blood nitrosyl-hemoglobin (NO-Hb) levels. Materials and Methods: This was a prospective, controlled, experimental study conducted in an animal research laboratory on 15 male mongrel dogs. Escherichia coli endotoxin (1 mg/kg) was injected intravenously. Results: Hepatic, renal, and iliac blood flow and cardiac output (CO) were measured before and 15, 30, 45, 90 and 180 minutes after injection of Escherichia coli endotoxin (1 mg/kg) (n = 6). NOx efflux from the organs was calculated by measuring plasma NOx levels. The arterial blood levels of NO-Hb were also measured (n = 4). As control studies, blood samples from dogs (n = 5) without exposure to endotoxin were assayed at 180 minutes for NOx and NO-Hb. Following endotoxin injection, mean arterial pressure decreased and reached its lowest value at 90 minutes (baseline vs. 90 minutes: 119.1 ± 5.8 vs. 82.5 ± 16.7 mm Hg, P< .0001). Hepatic artery blood flow increased significantly (baseline vs. 180 minutes: 23.6 ± 12.0 vs. 170.0 ± 68.4 mL/ min, P < .0001). There were no significant changes in plasma levels of NOx, uptake or release of NOx across the measured vascular beds, NO-Hb levels at any time point. In the portal system, the portal vein flow correlated with NOx release (R = 0.69, P < .0001). Conclusion: in the early phase of endotoxemia in the dog, the significant reduction in systemic vascular resistance and hepatic arterial resistance are not associated with any measurable NOx release in the systemic circulation or the liver.

Published
1999

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