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33 results on '"Tani, Tomofumi"'

2. Glaucoma Diagnostic Performance of Retinal Blood Flow Measurement With Doppler Optical Coherence Tomography

Author

Abe, Tsubasa, primary, Yoshioka, Takafumi, additional, Song, Youngseok, additional, Tani, Tomofumi, additional, Kawai, Motofumi, additional, Omae, Tsuneaki, additional, Takahashi, Kengo, additional, Takizawa, Yoshitaka, additional, Ro-Mase, Tomoko, additional, Ishiko, Satoshi, additional, Minamide, Kana, additional, Sakai, Jun, additional, Akiba, Masahiro, additional, Hashimoto, Yohei, additional, and Yoshida, Akitoshi, additional

Published
2022
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5. Retinal Blood Velocity Waveform Characteristics With Aging and Arterial Stiffening in Hypertensive and Normotensive Subjects

Author

Takizawa, Yoshitaka, primary, Song, Youngseok, additional, Tani, Tomofumi, additional, Yoshioka, Takafumi, additional, Takahashi, Kengo, additional, Abe, Tsubasa, additional, Ro-Mase, Tomoko, additional, Ishiko, Satoshi, additional, Sakai, Jun, additional, Minamide, Kana, additional, Akiba, Masahiro, additional, Tatsukawa, Takamitsu, additional, Azuma, Nobuyoshi, additional, and Yoshida, Akitoshi, additional

Published
2021
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10. Retinal blood flow reduction in normal-tension glaucoma with single-hemifield damage by Doppler optical coherence tomography

Author

Yoshioka, Takafumi, primary, Song, Youngseok, additional, Kawai, Motofumi, additional, Tani, Tomofumi, additional, Takahashi, Kengo, additional, Ishiko, Satoshi, additional, Lavinsky, Fabio, additional, Wollstein, Gadi, additional, Ishikawa, Hiroshi, additional, Schuman, Joel S, additional, and Yoshida, Akitoshi, additional

Published
2020
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11. Longitudinal Changes in Retinal Blood Flow in a Feline Retinal Vein Occlusion Model as Measured by Doppler Optical Coherence Tomography and Optical Coherence Tomography Angiography

Author

Wada, Takanari, primary, Song, Youngseok, additional, Oomae, Tsuneaki, additional, Sogawa, Kenji, additional, Yoshioka, Takafumi, additional, Nakabayashi, Seigo, additional, Takahashi, Kengo, additional, Tani, Tomofumi, additional, Ishibazawa, Akihiro, additional, Ishiko, Satoshi, additional, and Yoshida, Akitoshi, additional

Published
2020
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14. A low meat diet increases the risk of open-angle glaucoma in women—The results of population-based, cross-sectional study in Japan

Author

Kinouchi, Reiko, primary, Ishiko, Satoshi, additional, Hanada, Kazuomi, additional, Hayashi, Hiroki, additional, Mikami, Daiki, additional, Tani, Tomofumi, additional, Zenimaru, Tatsuya, additional, Kawai, Motofumi, additional, Nakabayashi, Seigo, additional, Kinouchi, Motoshi, additional, and Yoshida, Akitoshi, additional

Published
2018
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15. Retinal blood flow reduction in normal-tension glaucoma with single-hemifield damage by Doppler optical coherence tomography

Author

Yoshioka, Takafumi, Song, Youngseok, Kawai, Motofumi, Tani, Tomofumi, Takahashi, Kengo, Ishiko, Satoshi, Lavinsky, Fabio, Wollstein, Gadi, Ishikawa, Hiroshi, Schuman, Joel S, and Yoshida, Akitoshi

Abstract

AimsTo evaluate the associations between retinal blood flow (RBF) and optical coherence tomography (OCT) structural measurements in normal-tension glaucoma (NTG) eyes with single-hemifield visual field (VF) damage by the Doppler OCT.MethodsThe Doppler OCT was used to measure temporal artery (TA) RBF and temporal vein (TV) RBF. Retinal nerve fibre layer thickness (RNFLT) was measured by spectral-domain OCT.ResultsForty-three consecutive eyes of 43 patients with NTG with VF defect confined to a single hemifield and 24 eyes of 24 age-matched healthy subjects were studied. TA and TV RBF and RNFLT were reduced in the damaged hemisphere compared with the normal hemisphere (mean (SD), 3.61 (1.68) vs 5.86 (2.59) µL/min, p<0.001; 5.61 (2.51) vs 6.94 (2.83) µL/min, p=0.010; 69.0 (19.7) vs 99.7 (22.8) µm, p<0.001). Those values in the normal hemisphere of NTG eyes also decreased compared with the healthy hemisphere of the healthy eyes (8.40 (3.36) µL/min, p<0.001; 9.28 (4.47) µL/min, p<0.002; 122.8 (20.2) µm, p<0.001). Multivariate model showed that normal and damaged hemispheres and RNFLT were associated with RBF reduction. In addition, the RBF in the normal hemisphere was lower than that in the healthy hemisphere even after adjusting for RNFLT.ConclusionIn NTG eyes with single-hemifield damage, the RBF was significantly reduced in the damaged hemisphere compared with the normal one. The RBF decreased in the normal and damaged hemispheres of NTG eyes compared with the healthy hemisphere independent from RNFLT.

Published
2021
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18. En-face optical coherence tomography angiography of neovascularization elsewhere in hemicentral retinal vein occlusion

Author

Sogawa, Kenji, Nagaoka,Taiji, Ishibazawa,Akihiro, Takahashi,Atsushi, Tani,Tomofumi, and Yoshida,Akitoshi

Subjects
genetic structures, sense organs, International Medical Case Reports Journal, eye diseases
Abstract

Kenji Sogawa, Taiji Nagaoka, Akihiro Ishibazawa, Atsushi Takahashi, Tomofumi Tani, Akitoshi Yoshida Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan Purpose: To evaluate how the growth of neovascularization elsewhere (NVE) was delineated in an eye with hemicentral retinal vein occlusion (CRVO) using optical coherence tomography (OCT) angiography. Patients and methods: We examined a 64-year-old man diagnosed with hemi-CRVO. The area around the occluded vein was scanned using a spectral-domain OCT device (RTVue XR Avanti). Blood flow was detected using the split-spectrum amplitude-decorrelation angiography (SSADA) algorithm. Color fundus photography, fluorescein angiography (FA), and OCT angiography examinations were performed at the first visit and at 3 and 6 months postpresentation. Results: At the first visit, FA revealed delayed retinal venous filling and extensive areas of capillary nonperfusion. The patient underwent a trial of intravitreal ranibizumab injection (0.5 mg/0.05 mL) for the treatment of macular edema. At 3 months postpresentation, there was no NVE around the occluded vein in the en-face SSADA image, but at 6 months, NVE appeared on the occluded veins. The en-face SSADA image showed the NVE structure in the fibrovascular membrane on the occluded vein more clearly than FA images. Conclusion: OCT angiography clearly visualized the sprouting of NVE in an eye with hemi-CRVO. New findings of the vascular structure of NVE in hemi-CRVO were revealed using the en-face SSADA algorithm. Keywords: OCT angiography, hemi-CRVO, NVE

Published
2015

21. En-face optical coherence tomography angiography of neovascularization elsewhere in hemicentral retinal vein occlusion

Author

Sogawa,Kenji, Nagaoka,Taiji, Ishibazawa,Akihiro, Takahashi,Atsushi, Tani,Tomofumi, Yoshida,Akitoshi, Sogawa,Kenji, Nagaoka,Taiji, Ishibazawa,Akihiro, Takahashi,Atsushi, Tani,Tomofumi, and Yoshida,Akitoshi

Abstract

Kenji Sogawa, Taiji Nagaoka, Akihiro Ishibazawa, Atsushi Takahashi, Tomofumi Tani, Akitoshi Yoshida Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan Purpose: To evaluate how the growth of neovascularization elsewhere (NVE) was delineated in an eye with hemicentral retinal vein occlusion (CRVO) using optical coherence tomography (OCT) angiography. Patients and methods: We examined a 64-year-old man diagnosed with hemi-CRVO. The area around the occluded vein was scanned using a spectral-domain OCT device (RTVue XR Avanti). Blood flow was detected using the split-spectrum amplitude-decorrelation angiography (SSADA) algorithm. Color fundus photography, fluorescein angiography (FA), and OCT angiography examinations were performed at the first visit and at 3 and 6 months postpresentation. Results: At the first visit, FA revealed delayed retinal venous filling and extensive areas of capillary nonperfusion. The patient underwent a trial of intravitreal ranibizumab injection (0.5 mg/0.05 mL) for the treatment of macular edema. At 3 months postpresentation, there was no NVE around the occluded vein in the en-face SSADA image, but at 6 months, NVE appeared on the occluded veins. The en-face SSADA image showed the NVE structure in the fibrovascular membrane on the occluded vein more clearly than FA images. Conclusion: OCT angiography clearly visualized the sprouting of NVE in an eye with hemi-CRVO. New findings of the vascular structure of NVE in hemi-CRVO were revealed using the en-face SSADA algorithm. Keywords: OCT angiography, hemi-CRVO, NVE

Published
2015

30. Anteroposterior Tortuosity of the Retinal Vein at Arteriovenous Crossings in Healthy Subjects.

Author

Sogawa, Kenji, Nagaoka, Taiji, Tani, Tomofumi, and Yoshida, Akitoshi

Subjects
TORTUOSITY, RETINAL vein, ARTERIOVENOUS fistula, EPITHELIUM, OPTICAL coherence tomography, DISEASES
Abstract

Purpose: The purpose of this study was to investigate the effects of aging on anteroposterior tortuosity of the retinal vein at the arteriovenous (AV) crossing in healthy subjects. Methods: We examined 48 eyes of 24 healthy older Japanese subjects (>60 years), and, as controls, 42 eyes of 21 healthy younger Japanese subjects (<30 years). Retinal vein images at the AV crossing were obtained by optical coherence tomography. The depth of the vein was measured vertically from the outer border of the retinal pigment epithelium to the outer vein wall. We defined “m” as the deepest point of the vein at the AV crossing and “M” as the shallowest point. To evaluate the anteroposterior tortuosity of the retinal vein, we calculated the ratiom/M. Results: Meanm, M, andm/Min older subjects were 76.5 ± 13.1 µm, 142.7 ± 21.2 µm, and 0.52 ± 0.09, respectively. In younger control subjects, the values were 64.1 ± 12.6 µm, 139.9 ± 22.4 µm, and 0.46 ± 0.06. The values of “M” were not significantly different between groups, whereas both “m/M” and “m” were significantly (p = 0.021) lower in the older subjects than in the younger subjects. Conclusion: Anteroposterior tortuosity of the retinal vein was evaluated based on the maximum and minimum retinal vein depth measurements at the AV crossing using optical coherence tomography. Anteroposterior tortuosity of the retinal vein at the AV crossing is increased with age. [ABSTRACT FROM AUTHOR]

Published
2015
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32. Impaired Systemic Vascular Endothelial Function in Patients with Branch Retinal Vein Occlusion.

Author

Tanano, Ichiro, Nagaoka, Taiji, Sogawa, Kenji, Tani, Tomofumi, Omae, Tsuneaki, Nakabayashi, Seigo, Ishibazawa, Akihiro, and Yoshida, Akitoshi

Abstract

Purpose: To evaluate systemic endothelial function in patients with branch retinal vein occlusion (BRVO). Methods: Twenty-seven patients with BRVO (BRVO group, 8 men, 19 women; mean age, 65.4 ± 1.3), 10 patients with systemic hypertension and no other systemic or ocular disease (hypertension group, 6 men, 4 women; mean age, 70.4 ± 2.2), and 10 healthy volunteers (healthy group, 3 men, 7 women; mean age, 63.8 ± 2.1) were enrolled. We excluded patients with diabetes mellitus and current smokers. Using high-resolution ultrasonographic imaging, we evaluated the brachial artery (mm) to evaluate the flow-mediated vasodilation (FMD) by measuring the diameter of the brachial artery during reperfusion after arterial occlusion. Results: There were no significant differences among the three groups in age ( p = 0.98), sex ( p = 0.21), or the baseline diameter of the brachial artery ( p = 0.11). The group-averaged FMD value decreased significantly in the BRVO group (4.6 ± 0.4%) compared to the hypertension group (8.0 ± 0.8%, p < 0.01) and the healthy group (6.9 ± 0.6%, p < 0.05). Multiple logistic regression analysis identified lower FMD as an independent risk factor for BRVO. Conclusions: The results suggested that BRVO is associated with generalized endothelial dysfunction and that impaired systemic endothelial function may be associated with BRVO. [ABSTRACT FROM AUTHOR]

Published
2013
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33. Abnormality of retinal arterial velocity profiles using Doppler Fourier-domain optical coherence tomography in a case of Takayasu's arteritis with aortic regurgitation.

Author

Tani T, Takahashi A, Nagaoka T, and Yoshida A

Abstract

Purpose: To evaluate the retinal microcirculation using a segmental-scanning Doppler optical coherence tomography (DOCT) flowmeter in a patient with Takayasu's arteritis (TA) with aortic valve regurgitation (AR)., Observations: We measured the retinal blood velocity (V), retinal blood flow (RBF), and retinal blood velocity profiles (RBVP) of the major retinal arterioles using a DOCT flowmeter. The arteries were measured at the straight portion 1 disc diameter from the optic disc. Horizontal velocity profiles were extracted to evaluate the RBVP during one cardiac cycle. A patient with TA with stage 2 Takayasu retinopathy (TR) and AR, had normal RBF and V, and the RBVP had a parabolic pattern in the systolic phase. However, the V was very slow and the RBVP had an abnormal pattern in the diastolic phase., Conclusions and Importance: The current study showed for the first time that segmental-scanning DOCT flowmeter enables evaluation of an abnormal flow pattern of the RVBP in the retinal arterioles in a patient with TA and AR. Measurement of the retinal arterial blood flow may detect aortic valve dysfunction and shed light on the pathogenesis of TR.

Published
2016
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