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247 results on '"Tandon, Sudeep"'

5. Towards the development of phytoextract based healthy ageing cognitive booster formulation, explored through Caenorhabditis elegans model

Author

Pandey, Rakesh, Mani, Dayanandan, Shanker, Karuna, Bawankule, Dnyaneshwar Umrao, Chanda, Debabrata, Lal, Raj Kishori, Pal, Anirban, Khare, Puja, Kumar, Narendra, Tandon, Sudeep, Saikia, Dharmendra, Gupta, Anil Kumar, Srivastava, Ramesh Kumar, Kumar, Sanjay, Suresh, Ram, Singh, Saudan, Kalra, Alok, Maurya, Anil, Singh, Dewasya Pratap, Pandey, Taruna, Trivedi, Shalini, Smita, Shachi Suchi, Pant, Akanksha, Rathor, Laxmi, Asthana, Jyotsna, Trivedi, Mashu, and Trivedi, Prabodh Kumar

Published
2022
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19. Synthesis of 6-alkoxy and 6-hydroxy-alkyl amine derivatives of braylin as vasorelaxing agents

Author

Nainawat, Kripa Shankar, primary, Singh, Sarita, additional, Agarwal, Karishma, additional, Iqbal, Hina, additional, Rani, Poonam, additional, Bhatt, Divya, additional, Khan, Sana, additional, Chanda, Debabrata, additional, Bawankule, Dnyaneshwar Umrao, additional, Tandon, Sudeep, additional, Khan, Feroz, additional, Kumar Gupta, Anil, additional, and Gupta, Atul, additional

Published
2023
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23. Green and proficient process for industrial-scale preparation of Gymnema sylvestre standardized-extract enriched with Gymnemic acids through polymer-matrix-adsorption to reduce hyperglycemia

Author

Kumar, Deepak, primary, Singh, Vipin Kumar, additional, Yadav, Narayan Prasad, additional, Tandon, Sudeep, additional, Shanker, Karuna, additional, Chanotiya, Chandan Singh, additional, Kumar, Narendra, additional, Khare, Puja, additional, Pal, Anirban, additional, Chanda, Debabrata, additional, Saikia, Dharmendra, additional, Hussain, Yusuf, additional, Meena, Abha, additional, Dhawan, Sunita Singh, additional, and Rout, Prasanta Kumar, additional

Published
2022
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26. Isoliquiritigenin, Liquiritigenin Rich Root Extract of Glycyrrhiza glabra Attenuates Inflammation in Macrophages and Collagen-Induced Arthritis in Rats

Author

babu, Vineet, primary, Kapkoti, Deepak Singh, additional, Binwal, Monika, additional, Bhakuni, Rajendra S., additional, Shanker, Karuna, additional, singh, Manju, additional, Tandon, Sudeep, additional, Mugale, Madhav N., additional, Kumar, Narendra, additional, and Bawankule, Dnyaneshwar Umrao, additional

Published
2022
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31. Chemical investigation, quality assessment, and antimicrobial activity of davana (Artemisia pallens Wall. ex DC) essential oil collected from different locations in India

Author

Singh, Swati, primary, Kurmi, Alka, additional, Gowda, M. R. Swamy, additional, Singh, Munmun Kumar, additional, Hiremath, Channayya, additional, Sundaresan, Velusamy, additional, Tandon, Sudeep, additional, Padalia, Rajendra Chandra, additional, Verma, Rajesh Kumar, additional, Saikia, Dharmendra, additional, and Verma, Ram Swaroop, additional

Published
2022
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32. Chemical composition and antimicrobial activity of the leaf essential oil of Ravenia spectabilis Engl. (Rutaceae)

Author

Singh, Swati, Kurmi, Alka, Singh, Munmun Kumar, Kashyap, Praveen Kumar, Tandon, Sudeep, Chauhan, Amit, Padalia, Rajendra Chandra, Saikia, Dharmendra, and Verma, Ram Swaroop

Abstract

Ravenia spectabilis Engl. belongs to the family Rutaceae is known to possess several biologically active phytomolecules. This study was planned to investigate the chemical composition and antimicrobial activity of the leaf essential oil of R. spectabilis. The hydrodistillation of fresh leaves of R. spectabilis gave 0.19 ± 0.02% essential oil. The resulting essential oil was analysed by gas chromatography-flame ionization detector (GC-FID) and gas chromatography-mass spectrometry (GC-MS). Altogether, thirty-one constituents forming 97.6 ± 1.72% of the total oil composition were identified. Major components of the oil were sabinene (60.8 ± 0.36%), α-pinene (5.4 ± 0.30%), myrcene (4.8 ± 0.25%), δ-3-carene (4.7 ± 0.62%) and β-pinene (4.3 ± 0.17%). The in-vitro antimicrobial potential of the oil was examined against eight human pathogenic bacterial and fungal strains. The essential oil showed significant activity against Staphylococcus aureus, Staphylococcus epidermidis, methicillin-resistant Staphylococcus aureus, methicillin-resistant Staphylococcus epidermidis, Candida albicans, and Candida kefyr. This is the first report on R. spectabilis leaf essential oil composition and its antimicrobial activity. The essential oil could be a promising natural source of sabinene and antimicrobial for developing new phytotherapeutics.

Published
2022
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33. New Insights into the Chemical Composition, Pro‐Inflammatory Cytokine Inhibition Profile of Davana ( Artemisia pallens Wall. ex DC.) Essential Oil and cis‐ Davanone in Primary Macrophage Cells

Author

Singh, Swati, primary, Bhatt, Divya, additional, Singh, Munmun Kumar, additional, Sundaresan, Velusamy, additional, Tandon, Sudeep, additional, Padalia, Rajendra Chandra, additional, Bawankule, Dnyaneshwar Umrao, additional, and Verma, Ram Swaroop, additional

Published
2021
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35. Pharmacological and Toxicological Study of Coumarinolignoids from Cleome viscosa in Small Animals for the Management of Rheumatoid Arthritis.

Author

Babu, Vineet, Singh, Rupali, Kashyap, Praveen K., Washimkar, Kaveri R., Mugale, Madhav N., Tandon, Sudeep, and Bawankule, Dnyaneshwar Umrao

Subjects
INTERLEUKINS, LIGNANS, ANIMAL experimentation, ORAL drug administration, RATS, RHEUMATOID arthritis, TUMOR necrosis factors, PLANT extracts
Abstract

This study aims to explore the possible pharmacological potential of Cleome viscosa Linn (Cleomaceae), an annual weed, into therapeutic value-added products. In the present study, we have explored the pharmacological and toxicological profile of coumarinolignoids isolated from Cleome viscose for the management of rheumatoid arthritis and related complications in a small animal model. To avoid the biasness during experiments on animals, we have coded the isolated coumarinolignoids as CLIV-92 to perform the experimental pharmacological study. CLIV-92 was orally administrated (30,100, 300 mg/kg) to animal models of collagen-induced arthritis (CIA), carrageenan-induced acute inflammation, thermal and chemical-induced pain, and Brewerʼs yeast-induced pyrexia. Oral administration of CLIV-92 significantly decreases the arthritis index, arthritis score, and increases the limb withdrawal threshold in the CIA model in experimental rats. The anti-arthritis studies revealed that the anti-inflammatory effect of CLIV-92 was associated with inhibition of the production of inflammatory mediators like TNF- α , IL-6, IL-17A, MMP-1, MMP-9, Nitric oxide, and C-RP in CIA ratʼs serum, and also reduced the NF к B-p65 expression as evidence of immunohistochemistry in knee joint tissue of CIA rats, in a dose-dependent manner. Further individual experiments related to arthritis-related complications in experimental animals demonstrated the analgesic, anti-inflammatory, and antipyretic potential of CLIV-92 in a dose-dependent manner. Further, an in-vivo acute oral toxicity study concluded that CLIV-92 is safe in experimental animals up to 2,000 mg/kg dose. The results of this study suggested that the oral administration of CLIV-92 may be a therapeutic candidate for further investigation in the management of rheumatoid arthritis and related complications. [ABSTRACT FROM AUTHOR]

Published
2023
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39. Chemical investigation, quality assessment, and antimicrobial activity of davana (Artemisia pallensWall. ex DC) essential oil collected from different locations in India

Author

Singh, Swati, Kurmi, Alka, Gowda, M. R. Swamy, Singh, Munmun Kumar, Hiremath, Channayya, Sundaresan, Velusamy, Tandon, Sudeep, Padalia, Rajendra Chandra, Verma, Rajesh Kumar, Saikia, Dharmendra, and Verma, Ram Swaroop

Abstract

ABSTRACTArtemisia pallensWall. ex DC, commonly known as davana, is cultivated in India for extraction of its essential oil (DO). In this study, DO collected from thirteen locations (DO1-DO13) and those extracted from six different phenophases and different plant parts were investigated using GC-FID and GC-MS. Altogether, 84 constituents were identified, forming 81.0–96.2% of the total oil composition. Major components of the oils were cis-davanone (17.4–65.1%), bicyclogermacrene (4.0–22.0%), cis-methyl jasmonate (0.4–8.5%), β-eudesmol (0.3–6.6%), davana ether isomer (0.5–6.1%), trans-ethyl cinnamate (1.4–6.1%), and germacrene D (0.1–4.7%). Among all tested oils, the DO10, having low cis-davanone content (27.5%), was found more potent against test microorganisms. The oils collected from different locations showed variations in their physical properties, chemical composition, and antimicrobial activity. Based on the yield and cis-davanone content, the flower bud and full-flowering stages could be suitable for harvesting good quality oil in north Indian plains.

Published
2022
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42. Brevifoliol ester induces apoptosis in prostate cancer cells by activation of caspase pathway

Author

Bhukya, Balakishan, primary, Fatima, Kaneez, additional, Nagar, Abhishek, additional, Lakshmi, Vijaya, additional, Dubey, Poornima, additional, Kumar, Shailesh, additional, Kumar, Yogesh, additional, Luqman, Suaib, additional, Chanda, Debabrata, additional, Tandon, Sudeep, additional, Shanker, Karuna, additional, Khan, Feroz, additional, and Negi, Arvind S., additional

Published
2019
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46. New chemical constituent from the stem of Cuscuta reflexa Roxb. and its biological activities.

Author

Nooreen, Zulfa, Tandon, Sudeep, Yadav, Narayan Prasad, and Ahmad, Ateeque

Subjects
DODDER, CHLOROGENIC acid, CONVOLVULACEAE, PALMITIC acid, QUERCETIN
Abstract

Chemical investigations on the stem of Cuscuta reflexa Roxb. (Convolvulaceae) led to the isolation of one new compound characterised as 3′,4′-dimethoxy-1-phenyl-1α, 2-ethanediol (1), along with eight known compounds as tridecanyl palmitate, palmitic acid, n-pentatriacontane, n-triacont-21, 27-dien-1-ol, kaempherol, chlorogenic acid, 5,7-dimethoxyapigenin and quercitin. The chemical structures were established with the help of physical, chemical and spectroscopic methods. The antimicrobial potential of the new compound (1) was evaluated against three bacterial and three fungal pathogenic strain and showed significant activities. [ABSTRACT FROM AUTHOR]

Published
2021
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47. Chemical composition and antimicrobial activity of the essential oil of senescent leaves of guava (Psidium guajava L.).

Author

Chaturvedi, Trishna, Singh, Swati, Nishad, Indrajeet, Kumar, Ajay, Tiwari, Neha, Tandon, Sudeep, Saikia, Dharmendra, and Verma, Ram Swaroop

Subjects
GUAVA, ESSENTIAL oils, FOOD poisoning, PHYTOPATHOGENIC fungi, PATHOGENIC fungi
Abstract

The aim of the study was to investigate the chemical composition and antimicrobial activity of the essential oil of the senescent leaves of Psidium guajava L. (Myrtaceae). The hydrodistilled essential oil of the leaves was analysed by GC-FID and GC-MS. The antimicrobial activity of the oil was assessed against human and plant pathogenic microorganisms by disc diffusion, microdilution broth and poison food techniques. A total of forty-six constituents, representing 90.9% of the total oil composition were identified. Major constituents of the oil were limonene (29.1%), (E)-caryophyllene (15.7%), caryophyllene oxide (8.8%), caryophylla-4(12),8(13)-dien-5-ol (6.5%), (E)-nerolidol (4.0%), α-cadinol (3.4%), and muurola-4,10(14)-dien-1-β-ol (2.5%). The chemical composition of the examined essential oil was quite different from those reported earlier. The essential oil showed significant inhibition of human pathogenic bacteria (MIC: 0.065–0.261 mg/mL) and plant pathogenic fungi, namely Curvularia lunata (86.02%) and Fusarium chlamydosporum (82.80%). [ABSTRACT FROM AUTHOR]

Published
2021
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