37 results on '"Tandogan RN"'
Search Results
2. Arthroscopic treatment of symptomatic type D medial plica.
- Author
-
Uysal M, Asik M, Akpinar S, Ciftci F, Cesur N, and Tandogan RN
- Published
- 2008
- Full Text
- View/download PDF
3. Analysis of outcomes for surgically treated hip fractures in patients undergoing chronic hemodialysis.
- Author
-
Karaeminogullari O, Demirors H, Sahin O, Ozalay M, Ozdemir N, Tandogan RN, Karaeminogullari, Oguz, Demirors, Huseyin, Sahin, Orcun, Ozalay, Metin, Ozdemir, Nurhan, and Tandogan, Reha N
- Abstract
Background: Hip fractures in patients with end-stage renal disease are associated with frequent complications. This study analyzed clinical outcomes for patients on chronic hemodialysis who sustained hip fractures and were treated with a variety of fracture repair methods.Methods: Twenty-nine patients with thirty-two hip fractures were analyzed in three groups. Group 1 consisted of eleven hips in eleven patients with an intertrochanteric fracture that was treated with internal fixation; Group 2, thirteen hips in ten patients with a femoral neck fracture that was treated with screw fixation; and Group 3, eight hips in eight patients with a femoral neck fracture that was treated with hemiarthroplasty. The outcomes and early and late complications were recorded for each group. Survivorship analysis was performed, and the mortality and complication rates for the groups were compared.Results: In Group 1, eight complications occurred in six hips and nonunion developed in five hips. In Group 2, sixteen complications developed in eleven hips. Union was achieved in two of the thirteen hips, nine hips had nonunion, and two hips had osteonecrosis develop. In Group 3, only one hip had early complications, there were no late complications, and three patients died. The mean duration of follow-up was twenty-three months, and the overall mortality rate was 45%. There were no significant differences among the groups with respect to the cumulative survival proportions. Regression analysis of age, sex, and total hemodialysis duration in relation to mortality risk revealed that only age had a significant influence on mortality (p = 0.019).Conclusions: Surgical treatment of hip fractures in patients with end-stage renal disease who are on chronic hemodialysis is associated with frequent complications and a high mortality rate. Osteosynthesis is an acceptable option for treating intertrochanteric fractures and nondisplaced femoral neck fractures, but displaced femoral neck fractures should be treated with hemiarthroplasty. [ABSTRACT FROM AUTHOR]- Published
- 2007
4. Tunnel enlargement after arthroscopic anterior cruciate ligament reconstruction: comparison of bone-patellar tendon-bone and hamstring autografts.
- Author
-
Hersekli MA, Akpinar S, Ozalay M, Ozkoc G, Cesur N, Uysal M, Pourbagher A, Tandogan RN, Hersekli, Murat Ali, Akpinar, Sercan, Ozalay, Metin, Ozkoc, Gurkan, Cesur, Necip, Uysal, Mustafa, Pourbagher, Aysin, and Tandogan, Reha N
- Abstract
Bone tunnel enlargement associated with anterior cruciate ligament (ACL) reconstruction has recently become a topic of interest in the literature. This association was examined, along with the effect of femoral and tibial tunnel enlargement on the clinical results of ACL reconstruction performed with either bone-patellar tendon-bone (BPTB) or hamstring (HST) autografts. Forty-six patients underwent arthroscopic ACL reconstruction (23 receiving BPTB autograft and 23 HST) between March 1999 and July 2001. Thirty patients (13 receiving BPTB autograft and 17 HST) completed the last clinical and radiologic evaluations and were included in the study. The mean age of patients in the HST group was 29.8 years (range 18-39) and that in the BPTB group was 27.6 years (range 20-37). The mean follow-up period was 24.6 months (range 12-36) in HST group and 18.5 months (range 12-40) in BPTB group. The effect of tunnel enlargement on the clinical results was evaluated by comparing preoperative and postoperative Lysholm, Tegner, and International Knee Documentation Committee scores and ligament laxity measurements between and within the groups. Postoperative femoral and tibial tunnel diameters in both groups were significantly larger than their corresponding preoperative tunnel diameters. In an intergroup evaluation, the enlargement of the tibial tunnel was similar in both groups (P=.556), but the femoral tunnel diameter was significantly larger in the HST group than in the BPTB group (P>.001). Preoperative laxity of the knees significantly improved after the operations in both groups, but no difference between the groups was evident at the final follow-up visit. No correlation between tunnel widening and the clinical results of the BPTB and HST procedures was observed. [ABSTRACT FROM AUTHOR]
- Published
- 2004
- Full Text
- View/download PDF
5. Same same but different-Image-based versus imageless robotic-assisted total knee arthroplasty!
- Author
-
Hirschmann MT, Avram G, Graichen H, Tandogan RN, Mengis N, and Zaffagnini S
- Abstract
Competing Interests: The authors declare no conflict of interest.
- Published
- 2024
- Full Text
- View/download PDF
6. Trends in unicompartmental knee arthroplasty among 138 international experienced arthroplasty knee surgeons.
- Author
-
Marullo M, Tandogan RN, Kort N, Meena A, Attri M, Gomberg B, and D'Ambrosi R
- Abstract
Purpose: Unicompartmental knee arthroplasty (UKA) is an established option for treating isolated unicompartmental knee osteoarthritis (OA), but controversies still exist about patient selection, indications, perioperative management and alignment goals. This survey was designed to understand the current trends of experienced arthroplasty knee surgeons performing UKA., Methods: An online questionnaire was created with SurveyMonkey ® to assess global tendencies in the utilization of UKA. A link to the survey was shared with all ESSKA (European Society for Sports Traumatology, Knee Surgery and Arthroscopy) members. The questionnaire consisted of free and multiple-choice questions and was divided into four sections: demographic information, the surgical activity of the respondents, indications for surgery and postoperative alignment goals., Results: A total of 138 ESSKA members from 34 different countries completed the survey. A total of 81 % of the responders performed fewer than 50 UKAs per year; 53 % of UKAs represented less than 20 % of their knee replacements; 71 % used mainly or only fixed-bearing implants; 81 % performed UKA in a shorter time compared to TKA; and 61 % and 72 % were interested in custom-made UKA and robotics, respectively. Thirty-six percent considered a minimum postoperative alignment of 0° for medial UKA, and 32 % considered 10° as the maximum valgus deformity for lateral UKA. Fifty-five percent had no minimum age cut-off, 47 % had no BMI cut-off, and 57 % believed TKA was better than UKA in knees with concomitant high-grade patellofemoral OA. Approximately 50 % of the surgeons desired a coronal alignment that was the same as the predegeneration alignment., Conclusion: A high level of agreement was reached regarding the following: preference for fixed-bearing UKAs, lower surgical time for UKA compared to TKA, interest in custom-made and robotic UKAs, no age and weight cut-off, TKA preferred in the presence of patellofemoral OA, and a final alignment goal of the predegenerative state both for medial and lateral. There was no agreement regarding length of stay, rehabilitation protocol, preoperative varus and valgus cut-off values, and treatment in cases of absence of anterior cruciate ligament or previous osteotomy., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.., (© 2024 The Authors.)
- Published
- 2024
- Full Text
- View/download PDF
7. Tibial Tuberosity Rotation in Patients With Patellar Instability Versus Age- and Sex-Matched Controls.
- Author
-
Polat M, Tandogan RN, Solak EP, Bekiroglu GN, Beyzadeoglu T, and Kayaalp A
- Abstract
Background: Several methods have been described to measure external rotation of the tibial tuberosity; all use femoral landmarks., Purpose: To develop reproducible tibial-based methods to measure external rotation of the tibial tuberosity in patients with patellar instability., Study Design: Cross-sectional study; Level of evidence, 3., Methods: Included were magnetic resonance images of 61 patients with patellar instability and 61 age- and sex-matched healthy controls. Three novel methods using tibial landmarks to measure the rotation of the tibial tuberosity (plateau axis-tuberosity axis [PA-TA] angle, tibial geometric center-tuberosity axis [GC-TA] angle, and plateau axis-midtuberosity point [PA-MT] angle) as well as a femoral-based rotational measurement (surgical transepicondylar axis-tuberosity axis [sTEA-TA] angle) and the tibial tuberosity-trochlear groove (TT-TG) distance were measured and compared in instability patients and controls using unpaired t tests, and the cutoff values for predicting instability were calculated using receiver operating characteristic curves. The correlations between the angle measurements and the TT-TG distance were analyzed., Results: Instability patients had significantly higher external rotation of the tibial tuberosity compared with controls with regard to the PA-TA angle (18.2° ± 9.6° versus 13.1° ± 6.8°; P = .001), GC-TA angle (8.4° ± 4.5° versus 11.5° ± 3.9°; P = .0001) and sTEA-TA angle (122° ± 8.5° versus 113.6° ± 6.3°; P = .0001). The mean TT-TG distance was also significantly higher in the instability group (18.2 ± 5.4 versus 11.5 ± 2.7 mm; P = .001). The cutoff values were 17.5° (area under the receiver operating characteristic curve [AUC] = 0.66) for PA-TA angle, 8.5° (AUC = 0.705) for GC-TA angle, 118.8° (AUC = 0.79) for sTEA-TA angle, and 15.2 mm for TT-TG distance (AUC = 0.863). PA-TA angle was significantly correlated with all other measurements ( r = 0.35-0.71; P ≤ .006 for all), whereas sTEA-TA angle had the strongest correlation with TT-TG distance ( r = 0.78; P = .001)., Conclusion: The tibial tuberosity was externally rotated in patellar instability patients compared with age- and sex-matched controls, and this intrinsic malalignment of the proximal tibia was demonstrated in the tibial-based measurements., Competing Interests: One or more of the authors has declared the following potential conflict of interest or source of funding: R.N.T. has received nonconsulting fees from Smith & Nephew and Stryker and speaking fees from Menarini Pharma. A.K. has received nonconsulting fees from Smith & Nephew and Stryker. AOSSM checks author disclosures against the Open Payments Database (OPD). AOSSM has not conducted an independent investigation on the OPD and disclaims any liability or responsibility relating thereto., (© The Author(s) 2023.)
- Published
- 2023
- Full Text
- View/download PDF
8. Computer-assisted surgery and patient-specific instrumentation improve the accuracy of tibial baseplate rotation in total knee arthroplasty compared to conventional instrumentation: a systematic review and meta-analysis.
- Author
-
Tandogan RN, Kort NP, Ercin E, van Rooij F, Nover L, Saffarini M, Hirschmann MT, Becker R, and Dejour D
- Subjects
- Humans, Knee Joint surgery, Rotation, Tibia surgery, Arthroplasty, Replacement, Knee, Knee Prosthesis, Osteoarthritis, Knee surgery, Surgery, Computer-Assisted
- Abstract
Purpose: To determine whether patient-specific instrumentation (PSI), computer-assisted surgery (CAS) or robot-assisted surgery (RAS) enable more accurate rotational alignment of the tibial baseplate in primary total knee arthroplasty (TKA) compared to conventional instrumentation, in terms of deviation from the planned target and the proportion of outliers from the target zone., Methods: The authors independently conducted three structured electronic literature searches using the PubMed, Embase®, and Cochrane Central Register of Controlled Trials databases from 2007 to 2020. Studies were included if they compared rotational alignment of the tibial baseplate during TKA using conventional instrumentation versus PSI, CAS, and/or RAS, and reported deviation from preoperatively planned rotational alignment of the tibial baseplate in terms of absolute angles and/or number of outliers. Methodological quality of eligible studies was assessed by two researchers according to the Downs and Black Quality Checklist for Health Care Intervention Studies., Results: Fifteen studies, that reported on 2925 knees, were eligible for this systematic review, of which 6 studies used PSI, and 9 used CAS. No studies were found for RAS. Of the studies that reported on angular deviation from preoperatively planned rotational alignment, most found smaller deviations using PSI (0.5° to 1.4°) compared to conventional instrumentation (1.0° to 1.6°). All studies that reported on proportions of outliers from a target zone (± 3°), found lower rates of outliers using PSI (0 to 22%) compared to conventional instrumentation (5 to 96%). Most studies reported smaller angular deviation from preoperatively planned rotational alignment using CAS (0.1° to 6.9°) compared to conventional instrumentation (1.1° to 7.8°). Of the studies that reported on proportions of outliers from a target zone (± 3°), most found fewer outliers using CAS (10 to 61%) compared to conventional instrumentation (17 to 78%)., Conclusion: This systematic review and meta-analysis revealed that both CAS and PSI can improve the accuracy of rotational alignment of the tibial baseplate by decreasing angular deviation from the preoperatively planned target and reducing the proportion of outliers from the target zone. The clinical relevance is that PSI and CAS can improve alignment, though the thresholds necessary to grant better outcomes and survival remain unclear., Level of Evidence: IV., (© 2021. European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA).)
- Published
- 2022
- Full Text
- View/download PDF
9. Extensor mechanism ruptures.
- Author
-
Tandogan RN, Terzi E, Gomez-Barrena E, Violante B, and Kayaalp A
- Abstract
Native patellar tendon injuries are seen in younger patients compared to quadriceps tendon ruptures. Up to a third of the patients may have local (antecedent tendinopathy and cortisone injections) or systemic risk factors (obesity, diabetes, hyperparathyroidism, chronic renal failure, fluoroquinolone or statin use) of injury, these are more frequent in bilateral disruptions. Complete extensor mechanism disruptions should be repaired surgically. Although isolated primary repair has been reported to have good outcomes in younger patients with acute tears and good tendon quality, augmentation of the repair with autograft, allograft or synthetic material should be considered in patients with poor tendon quality, chronic tears or tendon defects. High rates of return to work/sports have been reported in native patellar and quadriceps tendon tears, with re-rupture rates <5%. Extensor mechanism disruptions in patients with a total knee arthroplasty are challenging due to older age, systemic co-morbidities and poor local conditions, resulting in inferior outcomes compared to native extensor mechanism injuries. Some form of augmentation with autograft, allograft or synthetics is advisable in all cases. Salvage procedures such as whole extensor mechanism allografts provide acceptable outcomes in multiply operated knees with extensive bone and soft tissue deficits.
- Published
- 2022
- Full Text
- View/download PDF
10. Safety, Efficacy, and Cost-Effectiveness of Simultaneous Bilateral Arthroscopic Bankart Repair for Bilateral Shoulder Instability.
- Author
-
Yildirim K, Pehlivanoglu T, Tandogan RN, and Beyzadeoglu T
- Abstract
Background: Bilateral shoulder instability and Bankart lesions are not rare and frequently require surgical treatment. Bilateral instability may be treated with either a single-stage, simultaneous bilateral Bankart repair or 2-stage surgery., Purpose/hypothesis: To compare simultaneous bilateral arthroscopic Bankart repair to 2-stage repair in terms of clinical outcomes and hospitalization costs. It was hypothesized that simultaneous repair would provide clinical outcomes similar to those of 2-stage Bankart repair while yielding lower hospitalization costs., Study Design: Cohort study; Level of evidence, 3., Methods: Patients who underwent simultaneous bilateral arthroscopic Bankart repair (group 1) were matched by age, sex, and injury type to control patients who had unilateral Bankart repair (group 2). All patients were operated on by the same surgeon in the same institution between 2007 and 2017 and had a minimum follow-up duration of 24 months. Patients with inflammatory arthritis, metabolic/malignant disease, previous shoulder surgery, a glenoid bone loss ≥25%, or off-track Hill-Sachs lesion were excluded. The 2 groups were compared in terms of pre- and postoperative Western Ontario Shoulder Instability Index (WOSI) scores, hospitalization costs, complications, and recurrent instability. The hospitalization cost of group 2 was multiplied by 2 to create a projection of the estimated cost of 2 sequential unilateral Bankart repairs., Results: The study population comprised 48 patients (38 men [79.17%] and 10 women [20.83%]; mean age, 25.5 years at surgery and 22.75 years at first dislocation). Group 1 included 32 shoulders in 16 patients, while group 2 consisted of 32 shoulders in 32 patients. The mean hospitalization cost (in 2020 US dollars) was $26,010 ± $1455 for group 1 and $33,591 ± $1574 for group 2 ( P < .001). Both groups had improved WOSI scores after surgery and achieved similar scores at the latest follow-up. There was 1 redislocation in each group (3.13%). No surgery- or anesthesia-related/medical complications were recorded in either group., Conclusion: For bilateral shoulder instability, clinical outcomes of simultaneous bilateral arthroscopic Bankart repair were similar to those of 2-stage repair; however, lower hospitalization costs were seen after simultaneous bilateral repair compared with 2-stage surgery., Competing Interests: The authors declared that they have no conflicts of interest in the authorship and publication of this contribution. AOSSM checks author disclosures against the Open Payments Database (OPD). AOSSM has not conducted an independent investigation on the OPD and disclaims any liability or responsibility relating thereto., (© The Author(s) 2022.)
- Published
- 2022
- Full Text
- View/download PDF
11. Prioritising of hip and knee arthroplasty procedures during the COVID-19 pandemic: the European Hip Society and the European Knee Associates Survey of Members.
- Author
-
Thaler M, Kort N, Zagra L, Hirschmann MT, Khosravi I, Liebensteiner M, Karachalios T, and Tandogan RN
- Subjects
- Communicable Disease Control, Humans, Pandemics, Reoperation, SARS-CoV-2, Surveys and Questionnaires, Arthroplasty, Replacement, Hip adverse effects, Arthroplasty, Replacement, Knee adverse effects, COVID-19
- Abstract
Purpose: During the COVID-19 pandemic there has been a massive reduction of arthroplasty services due to reallocation of hospital resources. The unique challenge for clinicians has been to define which arthroplasty patients most urgently require surgery. The present study aimed to investigate priority arthroplasty procedures during the pandemic and in the reinstatement period from the surgeon's perspective., Material and Methods: An online survey was conducted among members of the European Hip Society (EHS), European Knee Associates (EKA) and other invited orthopaedic arthroplasty surgeons (experts) from across the world. The survey consisted of 17 different arthroplasty procedures/indications of which participants were asked to choose and rank the most important 10., Results: Four hundred and thirty-nine arthroplasty surgeons from 44 countries responded. The EHS and EKA had a 43% response rate of members. In weighted average points, the majority of respondents (67.5 points) ranked 'acute fractures requiring arthroplasty (Periprosthetic fractures, THA/hemi-arthroplasty for femoral neck fractures)' as priority indication number one, followed by 'first-stage explantations for acute PJI (periprosthetic joint infection)' in second place and priority indication (45.9 points) three as 'one-stage revision for acute PJI' (39.7 points)., Conclusions: There was agreement that femoral neck fractures, periprosthetic fractures, and acute infections should be prioritised and cannot be postponed in the setting of the COVID-19 pandemic. As arthroplasty procedures are being resumed in most countries now, there has also been a relaxation of lockdown rules in most countries, which might cause a so-called second wave of the pandemic. Therefore, the results of the current study present a proposal by experts as to which operations should be prioritised in the setting of a second wave of the pandemic., (© 2021. European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA).)
- Published
- 2021
- Full Text
- View/download PDF
12. Twenty-one sports activities are recommended by the European Knee Associates (EKA) six months after total knee arthroplasty.
- Author
-
Thaler M, Khosravi I, Putzer D, Hirschmann MT, Kort N, Tandogan RN, and Liebensteiner M
- Subjects
- Arthroplasty, Replacement, Knee methods, Bicycling, Europe, Female, Golf, Humans, Knee Joint surgery, Male, Postoperative Period, Prospective Studies, Societies, Medical, Surveys and Questionnaires, Swimming, Tennis, Walking, Yoga, Arthroplasty, Replacement, Knee rehabilitation, Exercise, Return to Sport, Sports
- Abstract
Purpose: To elaborate recommendations for sports participation following TKA among the members of the European Knee Associates (EKA)., Methods: A prospective online survey was conducted among the members of the European Knee Associates (EKA). The European Knee Associates (EKA) are a section of the European Society of Sports Traumatology, Knee Surgery and Arthroscopy (ESSKA). The survey investigated recommendations for 47 sports disciplines. Possible answers were: allowed, allowed if experienced, not allowed, no opinion. The survey was conducted separately for 4 specific time frames: within 6 weeks after TKA; 6-12 weeks after TKA; 3-6 months after TKA; and more than 6 months after TKA. Consensus among the respondents was then analyzed., Results: EKA members (N = 120) participated in the survey. A high level of consensus was reached for a recommendation to allow 5 different sports in the first 6 weeks after TKA, 7 sports 6-12 weeks after surgery, 14 sports 3-6 months after TKA, and 21 out of 47 activities 6 months after surgery. In the first 6 weeks after TKA walking, stair climbing, swimming, aqua fitness, and static cycling were recommended. Six to twelve weeks after TKA, cycling on level ground and yoga were recommended in addition to the aforementioned activities. Further sports activities recommended beyond 12 weeks after TKA were: tennis doubles, golf, fitness/weight lifting, aerobics, hiking, Nordic walking and sailing. The sport for which the recommendation was "not allowed" following TKA was squash., Conclusion: The number of sports recommended by EKA surgeons increases stepwise over the postoperative time frames. The findings are regarded as clinically relevant as they may serve as a basis for answering patient questions on timing and giving recommendations for the resumption of sports activities following standard primary TKA and should be individualized by surgeons for their patients' expectations and goals., Level of Evidence: V.
- Published
- 2021
- Full Text
- View/download PDF
13. Topical co-delivery of platelet rich fibrin and tranexamic acid does not decrease blood loss in primary total knee arthroplasty compared to the standard of care: a prospective, randomized, controlled trial.
- Author
-
Tandogan RN, Polat M, Beyzadeoglu T, Karabulut E, Yildirim K, and Kayaalp A
- Subjects
- Administration, Intravenous, Administration, Topical, Aged, Double-Blind Method, Female, Humans, Knee Joint surgery, Male, Postoperative Hemorrhage etiology, Prospective Studies, Range of Motion, Articular, Standard of Care, Tourniquets adverse effects, Antifibrinolytic Agents administration & dosage, Arthroplasty, Replacement, Knee adverse effects, Blood Loss, Surgical prevention & control, Osteoarthritis, Knee surgery, Platelet-Rich Fibrin, Postoperative Hemorrhage prevention & control, Tranexamic Acid administration & dosage
- Abstract
Purpose: The purpose of this study was to evaluate the efficacy of intra-operative co-administration of tranexamic acid (TA) and platelet rich fibrin (PRF) using a proprietary co-delivery system on the amount of blood loss, early functional outcomes and wound complications after primary total knee arthroplasty (TKA). The intervention was compared to the standard of care (combined intravenous & topical TA) in a prospective, randomized, blinded setting., Methods: 80 patients undergoing primary cemented TKA without tourniquet were prospectively randomized into control (combined intravenous and topical TA) and PRF (intra-venous TA and co-delivery of topical PRF and TA) groups after informed consent. Total blood loss, drainage blood loss, knee range of motion, VAS pain scores, length of stay and wound complications were analysed. Data collection was performed in a double blind manner on days 1, 3 and 21., Results: There was no statistically significant difference in drainage blood loss (550 ml vs. 525 ml, p = 0.643), calculated total blood loss on day 1 (401 ml vs. 407 ml, p = 0.722), day 3 (467 ml vs 471 ml, p = 0.471) and day 21 (265 ml vs. 219 ml, p = 0.082) between the PRF and control groups respectively. The PRF group had a small but statistically significant increase in median knee extension in the early post-operative period, however this difference evened out at 3 weeks. No significant difference could be demonstrated between the PRF and control groups in length of stay, VAS pain scores, narcotic usage, wound complications and knee flexion at all time points., Conclusions: The topical co-delivery of PRF and TA does not significantly decrease blood loss in primary TKA compared to the standard of care. Slightly better active knee extension in the first 3 postoperative days can be achieved, however this benefit is not clinically relevant., Level of Evidence: I, Therapeutic study.
- Published
- 2021
- Full Text
- View/download PDF
14. Resuming hip and knee arthroplasty after COVID-19: ethical implications for wellbeing, safety and the economy.
- Author
-
Kort NP, Zagra L, Barrena EG, Tandogan RN, Thaler M, Berstock JR, and Karachalios T
- Subjects
- COVID-19, Coronavirus Infections prevention & control, Coronavirus Infections transmission, Elective Surgical Procedures, Humans, Pandemics prevention & control, Patient Selection, Pneumonia, Viral prevention & control, Pneumonia, Viral transmission, SARS-CoV-2, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Betacoronavirus, Coronavirus Infections epidemiology, Delivery of Health Care, Pneumonia, Viral epidemiology
- Abstract
Reinstating elective hip and knee arthroplasty services presents significant challenges. We need to be honest about the scale of the obstacles ahead and realise that the health challenges and economic consequences of the COVID-19 pandemic are potentially devastating.We must also prepare to make difficult ethical decisions about restarting elective hip and knee arthroplasty. These decisions should be based on the existing evidence-base, reliable data, the recommendations of experts, and regional circumstances.
- Published
- 2020
- Full Text
- View/download PDF
15. Clinical outcome after total knee replacement.
- Author
-
Becker R, Tandogan RN, and Karlsson J
- Published
- 2015
- Full Text
- View/download PDF
16. Intra-articular zoledronic acid in a rat osteoarthritis model: significant reduced synovitis may indicate chondroprotective effect.
- Author
-
Cınar BM, Ozkoc G, Bolat F, Karaeminogullari O, Sezgin N, and Tandogan RN
- Subjects
- Animals, Bone Density Conservation Agents administration & dosage, Cartilage, Articular drug effects, Chondrocytes pathology, Disease Models, Animal, Disease Progression, Injections, Intra-Articular, Male, Osteoarthritis, Knee pathology, Rats, Rats, Wistar, Synovial Membrane pathology, Synovitis etiology, Synovitis pathology, Zoledronic Acid, Cartilage, Articular pathology, Chondrocytes drug effects, Diphosphonates administration & dosage, Imidazoles administration & dosage, Osteoarthritis, Knee drug therapy, Synovitis drug therapy
- Abstract
Purpose: The aim of this experimental study was to evaluate the effect of intra-articular application of zoledronic acid (ZA) on joint cartilage and synovial tissue following induction of knee osteoarthritis (OA) in a rat model., Methods: An OA model was created by anterior cruciate ligament transection (ACLT) in the right knees of 48 adult Wistar albino rats. The rats were randomized into a study and control groups, each including 24 rats, and 10 μg of ZA was injected in 0.1 ml of sterile saline to 24 animals in the study group on the first day to operation and was repeated weekly until the rats were killed. The same volume of sterile saline was injected with the same schedule to the control group. Eight rats from both the study and control groups were killed, each time, on the 4th day, the 3rd week, and the 6th week after the operation. The groups were compared based on the histological scores of synovitis and cartilage destruction and the evaluation of serum markers., Results: Histological score indicates progression of synovitis was significantly less in the study group (p = 0.047). There was significant increase in the mean Mankin cartilage damage score in the control group (p = 0.021), while no significant change was found in the study group. When the two groups were compared over time, no statistically significant difference was detected in total histological scores, although there was a 47 % less incidence of cartilage tissue damage in the study group and better cartilage structure and tide mark integrity scores were also detected in the study group (p = 0.017 and p = 0.021, respectively)., Conclusion: Intra- articular zoledronic acid may suppress synovial inflammation. Furthermore, Zoledronic Acid does not reduce cartilage degeneration in early osteoarthritis models, but may provide some chondroprotective effect in ACLT- induced knee osteoarthritis model in rats.
- Published
- 2015
- Full Text
- View/download PDF
17. Knee joint synovial cyst following total knee arthroplasty with bone allograft.
- Author
-
Akpinar S, Circi E, Hersekli MA, Uysal M, Cesur N, and Tandogan RN
- Subjects
- Aged, Female, Humans, Knee Joint pathology, Osteoarthritis, Knee surgery, Recurrence, Synovial Cyst pathology, Synovial Cyst surgery, Tibia surgery, Transplantation, Homologous adverse effects, Arthroplasty, Replacement, Knee, Bone Transplantation adverse effects, Knee Joint surgery, Synovial Cyst etiology
- Abstract
Allograft has been shown to be highly successful for managing large osseous defects in total knee arthroplasty. We report a 68-year-old woman in whom a bone allograft had been used during total knee arthroplasty owing to a massive segmental medial tibia plateau defect 4 years earlier. Eighteen months after surgery, a 10x10 cm knee synovial cyst was detected by computed tomography scanning on the anteromedial side of the tibial plateau, and an en-bloc surgical excision was performed. At 36-month follow-up, a 16x12 cm cyst was found. Excision was again performed with removal of the allograft and application of an autologous iliac graft. After allograft removal, clinically and radiologically satisfactory results were achieved at the final follow-up.
- Published
- 2009
- Full Text
- View/download PDF
18. Radial tears in the root of the posterior horn of the medial meniscus.
- Author
-
Ozkoc G, Circi E, Gonc U, Irgit K, Pourbagher A, and Tandogan RN
- Subjects
- Adult, Age Distribution, Aged, Arthroscopy, Body Mass Index, Cohort Studies, Female, Humans, Knee Injuries surgery, Magnetic Resonance Imaging, Male, Middle Aged, Retrospective Studies, Risk Factors, Sex Distribution, Treatment Outcome, Knee Injuries epidemiology, Knee Injuries pathology, Tibial Meniscus Injuries
- Abstract
The purpose of this study is to define the clinical features and characteristics of radial tears in the root of the posterior horn of the medial meniscus and to report the outcome of arthroscopic treatment. Arthroscopic meniscus surgery was performed on 7,148 knees. Of those, 722 (10.1%) were radial tear in the root of the posterior horn of the medial meniscus. We reviewed the medical records from a random sample of 67 subjects studied (mean age 55.8 years, range 38-72, mean follow-up period 56.7 months, range, 8-123), which included surgical notes and detailed arthroscopic photographs of 70 knees. All patients were treated with arthroscopic partial meniscectomy. The age distribution, preoperative physical signs, results of magnetic resonance imaging , body mass index, and surgical findings of the study subjects were analyzed and the clinical results were graded with the Lysholm knee scoring scale and a questionnaire. Radiologic evaluation consisted of preoperative and at the latest follow-up radiographs. Eighty percent of the patients were older than 50 years, and 80.6% were either obese or morbidly obese. The mean Lysholm score improved from a preoperative value of 53 to a value of 67. The average preoperative Kellgren-Lawrence radiograph grade was 2 (range 0-3 points), a value that increased to 3 (range 2-4) at the latest follow-up, which showed a significant worsening. The preoperative MRI was reevaluated after the arthroscopic confirmation of a medial meniscal root tear. A tear could be demonstrated in only 72.9% of the patients, the rest of whom demonstrated degeneration and/or fluid accumulation at the posterior horn without a visible meniscal tear. Radial tears in the root of the medial meniscal posterior horn, which may not be visible in about one-third of the preoperative MRI scans, are common. That type of meniscal tear is strongly associated with obesity and older age and is morphologically different from the degenerative tears that often occur in the posterior horn. Partial meniscectomy provides symptomatic relief in most cases but does not arrest the progression of radiographically revealed osteoarthritis.
- Published
- 2008
- Full Text
- View/download PDF
19. Lipoma of the index finger.
- Author
-
Ersozlu S, Ozgur AF, and Tandogan RN
- Subjects
- Adult, Humans, Lipoma pathology, Male, Soft Tissue Neoplasms pathology, Fingers, Lipoma surgery, Soft Tissue Neoplasms secondary
- Published
- 2007
- Full Text
- View/download PDF
20. Necrotizing soft-tissue infection of a limb: clinical presentation and factors related to mortality.
- Author
-
Ozalay M, Ozkoc G, Akpinar S, Hersekli MA, and Tandogan RN
- Subjects
- Adult, Age Factors, Aged, Amputation, Surgical, Data Interpretation, Statistical, Debridement, Emergencies, Female, Humans, Male, Middle Aged, Reoperation, Retrospective Studies, Treatment Outcome, Diabetic Foot complications, Diabetic Foot diagnosis, Diabetic Foot mortality, Diabetic Foot surgery, Fasciitis, Necrotizing diagnosis, Fasciitis, Necrotizing mortality, Fasciitis, Necrotizing surgery, Leg surgery
- Abstract
Background: Necrotizing fasciitis is a rare and often fatal soft-tissue infection. Prompt diagnosis and immediate aggressive surgical debridement of all compromised tissues are critical to reducing morbidity and mortality in these rapidly progressive infections. The purpose of this study was to analyze the clinical presentation and evaluate factors that determine mortality associated with this uncommon surgical emergency., Methods: The study retrospectively investigated the medical records of 22 patients who were diagnosed and treated for necrotizing fasciitis of the lower extremity, 14 of whom had involvement of the foot (nine patients) or foot and ankle (five patients) at our hospital. The data collected for each of the 22 patients were age, sex, underlying systemic factors, location of infection, duration of symptoms, portal of entry of infection, initial diagnosis on admission, physical, radiographic and laboratory findings, microbiological cultures, the type of therapy used (debridement or amputation), treatment outcome, and number of days in the hospital., Results: A total of 23 extremities of 22 consecutive patients with necrotizing fasciitis who underwent surgical debridement or amputation were retrospectively reviewed. Radical surgical debridement was done in 16 extremities initially, and this treatment was repeated a mean of two times (range one to four debridements) to completely remove all the necrotic tissue. Nine patients (41%) required below-knee or above-knee amputation. There were three deaths, one related directly to sepsis and organ failure, one due to gastrointestinal hemorrhage, and one caused by pulmonary embolism. There were no significant differences between patients who had the amputations and those who did not with respect to mortality rate or age (p = 0.538 and p = 0.493, respectively). Those who died were significantly older than the survivors (p = 0.038)., Conclusions: The diagnosis of necrotizing fasciitis should be considered for any individual who has unexplained limb pain, especially if that person has diabetes mellitus or chronic liver disease. There was no difference in mortality rates between patients with or without amputation. The primary treatment is early and aggressive debridement of involved skin, subcutaneous fat, and fascia.
- Published
- 2006
- Full Text
- View/download PDF
21. Giant chondroblastoma of the scapula with pulmonary metastases.
- Author
-
Ozkoc G, Gonlusen G, Ozalay M, Kayaselcuk F, Pourbagher A, and Tandogan RN
- Subjects
- Humans, Male, Middle Aged, Radiography, Bone Neoplasms diagnosis, Chondroblastoma diagnosis, Chondroblastoma secondary, Lung Neoplasms diagnosis, Lung Neoplasms secondary, Scapula diagnostic imaging, Scapula pathology
- Abstract
A 53-year-old man presented with a 12-year history of a progressively growing solid mass at his left shoulder. A 39x30x18-cm and 14.440-kg mass including the scapula was resected. Pathologic features were specific for chondroblastoma. During the 36-month follow-up, he had multiple inoperable metastatic lesions in his lungs. Histology of the transthoracic needle biopsy showed the metastatic nodules had features specific for chondroblastoma; however, the microscopic features additionally had hyperchromasia and increased mitotic activity in some areas. In the English literature, there are a few cases of chondroblastoma located in the scapula. It is exceptional to see this lesion in the sixth decade of life and with pulmonary metastases.
- Published
- 2006
- Full Text
- View/download PDF
22. Time dependent changes in patellar tracking with medial parapatellar and midvastus approaches.
- Author
-
Ozkoc G, Hersekli MA, Akpinar S, Ozalay M, Uysal M, Cesur N, and Tandogan RN
- Subjects
- Aged, Female, Humans, Knee Joint diagnostic imaging, Male, Middle Aged, Postoperative Period, Preoperative Care, Prospective Studies, Radiography, Arthroplasty, Replacement, Knee methods, Joint Instability diagnostic imaging, Patella diagnostic imaging
- Abstract
The aim of this study was to compare the alteration of patellar tracking by time, which was performed through two different approaches: midvastus and medial parapatellar. Twenty-one patients undergoing simultaneous bilateral primary total knee replacements were randomized prospectively to perform the surgery via a medial parapatellar approach on one knee and midvastus approach on the other knee. All of the patellae were resurfaced. Preoperative, early and late postoperative (mean 22 month) skyline views of the patellae were taken. We found that preoperative 2.24 degrees lateral tilt of patella had not changed by time at the midvastus side (2.95 degrees and 2.57 degrees ). Moreover, preoperative 0.48% lateral subluxation of the patella for midvastus approach had not changed (1.48% and 1.67%). Although 2.19 degrees patellar lateral tilt had not significantly changed at the early postoperative period, which was performed via medial parapatellar approach, there had been a significant increase to 5.38 degrees by time (P=0.037) compared to the preoperative radiographs. Additionally, the preoperative lateral subluxation of the patella (0.57%) at the medial parapatellar side had increased to 5.43% at the early (P=0.009) and 5.62% at the late (P=0.012) postoperative measurements. Midvastus approach is superior to medial parapatellar approach concerning the late patellar tracking.
- Published
- 2005
- Full Text
- View/download PDF
23. Arthroscopic debridement and grafting of an intraosseous talar ganglion.
- Author
-
Uysal M, Akpinar S, Ozalay M, Ozkoç G, Cesur N, Hersekli MA, and Tandogan RN
- Subjects
- Adult, Humans, Male, Transplantation, Autologous, Transplantation, Heterotopic, Arthroscopy methods, Debridement methods, Ganglion Cysts surgery, Talus surgery, Tibia transplantation
- Abstract
We report the case of a 41-year-old man with right ankle pain and swelling who had an intraosseous talar ganglion in the medial part of talar dome. A surgical procedure was performed using the 3-portal arthroscopic approach. The softened chondral surface was removed and the content of the cyst was discharged arthroscopically. The sclerotic rim was abraded until the bleeding spongious layer was seen. A grafting procedure was also performed arthroscopically. A trocar was introduced into the defect from the superomedial portal. Autografts were impacted using a cylindrical rod through the trocar into the defect. The clinical and radiologic results at the 1-year follow-up were satisfactory. We encountered no complications postoperatively. We conclude that arthroscopic debridement and grafting of an intraosseous ganglion adjacent to the articular surface may be a better option compared with open surgery.
- Published
- 2005
- Full Text
- View/download PDF
24. Mechanical strength of four different biceps tenodesis techniques.
- Author
-
Ozalay M, Akpinar S, Karaeminogullari O, Balcik C, Tasci A, Tandogan RN, and Gecit R
- Subjects
- Alloys, Animals, Biomechanical Phenomena, Bone Nails, Equipment Failure, Materials Testing, Random Allocation, Sheep, Titanium, Weight-Bearing, Bone Screws, Implants, Experimental, Suture Techniques instrumentation, Tendons surgery
- Abstract
Purpose: The aim of this study was to compare the biomechanical properties of 4 different biceps tenodesis techniques., Type of Study: Biomechanical experiment., Methods: Four groups of fresh sheep shoulders (28 total) with similar shape characteristics were used. Biceps tenodesis was performed using the following techniques: group 1 (n = 7), tunnel technique; group 2 (n = 7), interference screw technique; group 3 (n = 7), anchor technique; and group 4 (n = 7), keyhole technique. Each construct was loaded to failure and the groups were compared with respect to maximum load in Newtons and deflection at maximum load in millimeters. The results were statistically analyzed with 1-way analysis of variance, the Bonferroni post hoc test and the Student t test or the nonparametric Mann-Whitney U test., Results: The calculated average maximum loads were 229.2 +/- 44.1 N for the tunnel technique, 243.3 +/- 72.4 N for the interference screw, 129.0 +/- 16.6 N for the anchor technique, and 101.7 +/- 27.9 N for the keyhole technique. Statistical testing showed no statistically significant differences between groups 1 and 2, groups 3 and 4, or groups 2 and 3 with respect to maximum load and deflection at maximum load (P = .09/P = .49, P = .41/P = .79, and P = .06/P = .82 for load/deflection in the 3 comparisons, respectively). However, all other group comparisons revealed significant differences for both parameters (group 1 v group 4 [P < .01/P < .01]; group 1 v group 3[P < .01/P = .01]; and group 2 v group 4 [P = .007/P = .003])., Conclusions: The strongest construct was made with the interference screw technique, followed by the tunnel, anchor, and keyhole techniques. There were no statistically significant differences between the interference screw and tunnel techniques with respect to maximum load or deflection at maximum load., Clinical Relevance: Although it is difficult to extrapolate in vitro data to the clinical situation, the interference screw technique has better initial biomechanical properties and may produce improved clinical outcomes.
- Published
- 2005
- Full Text
- View/download PDF
25. Hallucal sesamoid osteonecrosis: an overlooked cause of forefoot pain.
- Author
-
Ozkoç G, Akpinar S, Ozalay M, Hersekli MA, Pourbagher A, Kayaselçuk F, and Tandogan RN
- Subjects
- Adult, Female, Forefoot, Human, Humans, Male, Middle Aged, Osteonecrosis surgery, Pain etiology, Sesamoid Bones surgery, Hallux, Osteonecrosis complications, Sesamoid Bones pathology
- Abstract
Four cases of osteonecrosis of hallucal sesamoids are reported here. Surgical excision of necrotic sesamoid tissue yielded satisfactory results, with the patients reporting no residual pain. Although it has not been frequently addressed in the literature, avascular necrosis of the sesamoid bones should be considered in the differential diagnosis of persistent forefoot pain.
- Published
- 2005
- Full Text
- View/download PDF
26. Primary clear cell sarcoma of rib.
- Author
-
Hersekli MA, Ozkoc G, Bircan S, Akpinar S, Ozalay M, Tuncer I, and Tandogan RN
- Subjects
- Adult, Bone Neoplasms pathology, Bone Neoplasms radiotherapy, Bone Neoplasms surgery, Combined Modality Therapy, Diagnosis, Differential, Female, Humans, Sarcoma, Clear Cell pathology, Sarcoma, Clear Cell radiotherapy, Sarcoma, Clear Cell surgery, Tomography, X-Ray Computed, Bone Neoplasms diagnostic imaging, Ribs, Sarcoma, Clear Cell diagnostic imaging
- Abstract
Clear cell sarcoma (malignant melanoma of soft tissues) is a very rare soft tissue neoplasm. It generally arises in tendons and aponeuroses. Although metastasis of malignant melanoma to bone is not uncommon, primary clear cell sarcoma of bone is an extremely rare neoplasm. To our knowledge five cases have been reported in the English literature. We present a case of primary clear cell sarcoma of bone in a 28-year-old woman arising in the left ninth rib. We treated the patient with total excision of the mass and postoperative radiotherapy. The patient is alive and well without local recurrence or distant metastasis at 33 months after surgery.
- Published
- 2005
- Full Text
- View/download PDF
27. Synovial cysts of proximal tibiofibular joint causing peroneal nerve palsy: report of three cases and review of the literature.
- Author
-
Hersekli MA, Akpinar S, Demirors H, Ozkoc G, Ozalay M, Cesur N, Uysal M, and Tandogan RN
- Subjects
- Adult, Child, Female, Fibula, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Synovial Cyst diagnosis, Synovial Cyst surgery, Tibia, Knee Joint, Peroneal Neuropathies etiology, Synovial Cyst complications
- Abstract
Introduction: Synovial cyst of the proximal tibiofibular joint is a very rare condition, for which there is no consensus regarding treatment., Case Presentation: We present three patients who had synovial cysts of proximal tibiofibular joint that caused peroneal nerve palsy. We discuss the special features of synovial cysts and review the literature., Conclusion: We consider the best treatment of synovial cysts originating from proximal tibiofibular joint and causing peroneal nerve palsy to be total surgical removal as soon as possible after the diagnosis is made. It should be kept in mind that despite surgical treatment the neurological symptoms may not recover.
- Published
- 2004
- Full Text
- View/download PDF
28. Analysis of meniscal and chondral lesions accompanying anterior cruciate ligament tears: relationship with age, time from injury, and level of sport.
- Author
-
Tandogan RN, Taşer O, Kayaalp A, Taşkiran E, Pinar H, Alparslan B, and Alturfan A
- Subjects
- Adolescent, Adult, Age Factors, Analysis of Variance, Anterior Cruciate Ligament physiopathology, Cartilage, Articular injuries, Cartilage, Articular physiopathology, Female, Follow-Up Studies, Humans, Injury Severity Score, Male, Menisci, Tibial physiopathology, Middle Aged, Probability, Recovery of Function, Retrospective Studies, Risk Factors, Time Factors, Anterior Cruciate Ligament Injuries, Athletic Injuries diagnosis, Knee Injuries diagnosis, Tibial Meniscus Injuries
- Abstract
The purposes of this multi-center study were: (a) to document the location and type of meniscal and chondral lesions that accompany anterior cruciate ligament (ACL) tears, and (b) to test for possible relationships between these lesions and patient age, time from initial injury (TFI), and sports level (i.e., recreation, amateur, professional, and national). The cases of 764 patients with ACL tears who underwent arthroscopy for the first time were retrospectively analyzed. The group included 684 males and 80 females of mean age 27 years (range 14-59 years). The mean TFI was 19.8 months (range 0.2-360 months). Eighty-seven percent of the group engaged in regular sporting activity. Thirty-seven percent had medial meniscal tears, 16% had lateral meniscal tears, and 20% had tears of both menisci. The most common tear types were longitudinal tears in the posterior and middle horns of both menisci. Tears of the lateral meniscus were more centrally located than those of the medial meniscus. Incomplete tears and radial tears were significantly more common in the lateral meniscus. Nineteen percent of the knees had one or more chondral lesions. Sixty percent of the chondral lesions were located in the medial tibio-femoral compartment. Patient age was statistically associated with presence of a medial meniscal tear, presence of a grade 3 or 4 chondral lesion, and presence of a complex tear of the medial meniscus. Sports level was not statistically related to any of the parameters studied. The odds of having a medial meniscal tear at 2 to 5 years TFI were 2.2 times higher than the odds in the first year post-injury, and the odds at >5 years were 5.9 times higher than at 0 to 12 months TFI. The frequency of lateral meniscal tear remained fairly constant at 2 years TFI. The odds of having a grade 3 or 4 chondral lesion were 2.7 times greater at 2 to 5 years TFI than they were at 1 year post-injury, and these odds increased to 4.7 when patients at >5 years TFI were compared to those in the 2 to 5 years category. Multivariate analysis demonstrated that TFI and age were equally important predictors of lateral meniscal tears and of grade 3 or 4 chondral lesions; however, TFI was the better predictor of medial meniscal tear.
- Published
- 2004
- Full Text
- View/download PDF
29. The timing of tourniquet release and its influence on blood loss after total knee arthroplasty.
- Author
-
Hersekli MA, Akpinar S, Ozkoc G, Ozalay M, Uysal M, Cesur N, and Tandogan RN
- Subjects
- Aged, Female, Humans, Intraoperative Period, Male, Middle Aged, Osteoarthritis surgery, Prospective Studies, Time Factors, Arthroplasty, Replacement, Knee, Blood Loss, Surgical prevention & control, Hemostasis, Surgical, Tourniquets
- Abstract
We performed a prospective, randomized study on 76 patients (82 knees) scheduled for total knee arthroplasty to determine the effect of tourniquet release and hemostasis on the peri- and postoperative blood loss. Patients were randomly divided in two groups. Posterior cruciate retaining tricompartmental total knee prostheses were used in all. In group 1, the tourniquet was deflated intraoperatively after the prosthetic components were settled and hemostasis was done. In group 2, the tourniquet was released after the wound was closed and a compressive bandage was applied. Mean blood drainage was 880.85 ml (320-1,315) in group 1 and 745.36 ml (220-1,175) in group 2 ( p=0.03). The mean number of blood transfusions given, hemoglobin and hematocrit values, operation time, and tourniquet time were similar in both groups. Intraoperative tourniquet release and hemostasis does not reduce total blood loss in total knee arthroplasty.
- Published
- 2004
- Full Text
- View/download PDF
30. Effect of long-term steroid use on prognosis for patients with surgically treated avascular necrosis of the hip.
- Author
-
Demirors H, Kaya A, Akpinar S, Tuncay C, and Tandogan RN
- Subjects
- Adolescent, Adult, Female, Femur Head Necrosis chemically induced, Femur Head Necrosis diagnostic imaging, Humans, Kidney Transplantation immunology, Male, Middle Aged, Prognosis, Radiography, Surgical Procedures, Operative methods, Adrenal Cortex Hormones adverse effects, Femur Head Necrosis surgery, Kidney Transplantation physiology
- Published
- 2002
- Full Text
- View/download PDF
31. Effects of methylprednisolone and betamethasone injections on the rotator cuff: an experimental study in rats.
- Author
-
Akpinar S, Hersekli MA, Demirors H, Tandogan RN, and Kayaselcuk F
- Subjects
- Analysis of Variance, Animals, Disease Models, Animal, Female, Injections, Intra-Articular, Probability, Random Allocation, Rats, Rats, Sprague-Dawley, Reference Values, Shoulder Impingement Syndrome drug therapy, Shoulder Joint drug effects, Shoulder Joint physiopathology, Treatment Outcome, Betamethasone pharmacology, Methylprednisolone pharmacology, Rotator Cuff drug effects, Rotator Cuff pathology
- Abstract
Thirty-one female Sprague-Dawley rats were used to determine the effects of subacromial corticosteroid injections on the rotator cuff. The injection technique was tested in 6 animals, which were excluded from the study. The remaining 25 rats were randomly divided into three groups of 8 animals each; a single rat received no injections. Every other week for 8 weeks, one shoulder in each rat was injected with methylprednisolone, betamethasone, or saline in a dosage equivalent to that used in humans. The supraspinatus and infraspinatus tendons were removed 10 days after the last injection and evaluated. There were no pathologic changes in the tendons injected with saline. In 43% of the methylprednisolone-treated rats and 29% of the betamethasone-treated rats, the tendons were abnormally soft and light-colored. In 43% of the methylprednisolone group and 71% of the betamethasone group, fragmentation of collagen bundles and inflammatory cell infiltration were evident. Subacromial injections of methylprednisolone or betamethasone repeated frequently can cause deleterious changes in the normal structure of the rat rotator cuff. In light of these findings, therapy for subacromial impingement syndrome of the shoulder with frequent, repeated steroid injections is potentially harmful.
- Published
- 2002
- Full Text
- View/download PDF
32. Arthroscopic-assisted percutaneous screw fixation of select patellar fractures.
- Author
-
Tandogan RN, Demirors H, Tuncay CI, Cesur N, and Hersekli M
- Subjects
- Adult, Aged, Catheterization, Female, Fractures, Bone diagnosis, Fractures, Bone diagnostic imaging, Humans, Male, Middle Aged, Patella diagnostic imaging, Patella injuries, Radiography, Skin, Arthroscopy methods, Bone Screws, Fracture Fixation methods, Fractures, Bone surgery, Patella surgery
- Abstract
Purpose: To describe a technique of arthroscopic-assisted reduction and percutaneous cannulated screw fixation for displaced patellar fractures and to present the results of 5 cases., Type of Study: Case series., Methods: Five patients (3 male, 2 female) with displaced patellar fractures treated with an arthroscopic-assisted reduction and percutaneous cannulated screw fixation were prospectively analyzed. The mean age was 53 years (range, 27 to 74 years). All fractures were fixed with at least 2 4-mm cannulated screws under arthroscopic visualization. Cerclage wiring through the cannulated screws was necessary in 2 patients with osteopenic bone. Controlled passive range of motion exercises were started on the first postoperative day. Full weight bearing with an immobilizer-type brace was allowed as tolerated. The mean follow-up was 28 months (range, 24 to 35 months). The patients were evaluated with Lysholm II scores, clinical examination, knee range of motion, thigh circumference measurements, and radiographs., Results: All fractures healed uneventfully. The mean Lysholm II score was 84.8 (range, 75-96). All but 1 patient regained full knee range of motion. A mean quadriceps atrophy of 0.8 cm compared with the contralateral side was seen in unilateral cases. There was no implant failure or infection., Conclusions: Arthroscopic-assisted reduction and percutaneous cannulated screw fixation is appropriate for displaced transverse patellar fractures without major separation and comminution. Longitudinal or oblique fractures, even if there are more than 2 major fragments, are amenable to arthroscopic techniques, providing the fragments are large enough to be fixed with screws. This technique is minimally invasive and does not disturb the vascular supply of patella. It allows clear visualization of the reduction and stability of the fracture, and facilitates early postoperative range of motion exercises. This method is not suitable for highly comminuted fractures or transverse fractures with major separation that are accompanied by rupture of the extensor mechanism.
- Published
- 2002
- Full Text
- View/download PDF
33. Osteoid osteoma in the base of the coracoid process of the scapula. Excision by anterior approach: a case report.
- Author
-
Akpinar S, Demirors H, Hersekli MA, Yildirim T, Barutcu O, and Tandogan RN
- Subjects
- Adolescent, Bone Neoplasms diagnosis, Female, Humans, Osteoma, Osteoid diagnosis, Radionuclide Imaging, Tomography, X-Ray Computed, Bone Neoplasms surgery, Osteoma, Osteoid surgery, Scapula surgery
- Abstract
Osteoid osteoma in the base of the coracoid process of the scapula is very rare and diagnosis and treatment often is delayed. A lesion in this atypical location may seem surgically unreachable. This report is of a case of osteoid osteoma in the base of coracoid process in a 14-year-old female. The lesion had been diagnosed as a nontumorous condition and overlooked for four years. Computed tomography and magnetic resonance imaging revealed a nidus in the base of the coracoid process. The en bloc excision of the osteoid osteoma was managed by an anterior approach using an osteotomy of the coracoid process. A 12-month follow-up examination revealed no symptoms and computed tomography showed bone healing with no recurrence of the tumor.
- Published
- 2001
34. Two-stage treatment of chronic staphylococcal orthopaedic implant-related infections using vancomycin impregnated PMMA spacer and rifampin containing antibiotic protocol.
- Author
-
Isiklar ZU, Demirörs H, Akpinar S, Tandogan RN, and Alparslan M
- Subjects
- Adult, Aged, Anti-Bacterial Agents administration & dosage, Arthroplasty, Replacement, Hip methods, Chronic Disease, Female, Follow-Up Studies, Humans, Male, Middle Aged, Prospective Studies, Prosthesis-Related Infections surgery, Reoperation, Staphylococcal Infections surgery, Treatment Outcome, Arthroplasty, Replacement, Hip instrumentation, Hip Prosthesis adverse effects, Prosthesis-Related Infections drug therapy, Rifampin administration & dosage, Staphylococcal Infections drug therapy, Staphylococcus epidermidis isolation & purification, Vancomycin administration & dosage
- Abstract
To determine the clinical role of rifampin containing antibiotic combination and modified two-stage exchange arthroplasty with a vancomycin loaded polymethylmethacrylate (PMMA) spacer for the treatment of orthopaedic implant related Staphylococcus epidermidis infections, a prospective study was initiated. A total of 10 patients, with a mean age of 59 years (range: 32 to 78 years) were included in the study. The mean follow up was 23.4 months (range: 16 to 36 months). Six patients had an infected hemiarthroplasty of the hip, three had infected total hip arthroplasty, and one had an infected femoral neck fracture with implant failure and pseudoarthrosis. All had culture-proven Staphylococcus epidermidis infections, six of the isolates were methicillin resistant. Following debridement and implantation of a PMMA spacer, a rifampin-vancomycin antibiotic protocol was initiated until the erythrocyte sedimentation rate and C-reactive protein levels were within normal limits. After reimplantation and discharge from the hospital, oral antibiotics with rifampin-ciprofloxacin were continued for three to six months. At the final follow-up none of the patients had any clinical or laboratory signs of infection. Although this study includes a limited number of patients and relatively short-term follow-up the results indicate that in the presence of orthopaedic implant infection with Staphylococcus epidermidis, modified two-stage exchange arthroplasty using a vancomycin-loaded PMMA spacer and a rifampin-containing antibiotic protocol may be beneficial.
- Published
- 1999
35. Calcific myonecrosis.
- Author
-
Tuncay IC, Demirörs H, Isiklar ZU, Agildere M, Demirhan B, and Tandogan RN
- Subjects
- Calcinosis etiology, Follow-Up Studies, Humans, Leg, Male, Middle Aged, Muscular Diseases etiology, Necrosis, Treatment Outcome, Wounds, Gunshot complications, Calcinosis pathology, Calcinosis surgery, Muscular Diseases pathology, Muscular Diseases surgery
- Abstract
Calcific myonecrosis is a rare and late sequela of compartment syndrome, which becomes symptomatic years after the initial trauma. We diagnosed this condition in a 64-year old man, 42 years after he sustained a shot-gun wound to the right lower leg. Total excision of a peripherally calcified, cystic mass, continuous with the anterior tibial muscle belly resulted in complete resolution of symptoms. Consideration of the diagnosis is warranted in patients with a history of major injury who develop a soft tissue mass in the traumatized compartment. The treatment of choice is marginal excision.
- Published
- 1999
- Full Text
- View/download PDF
36. Intra-articular metastatic melanoma of the right knee.
- Author
-
Tandogan RN, Aydogan U, Demirhan B, Arican A, and Yücetürk A
- Subjects
- Arthrography, Arthroscopy, Bone Neoplasms diagnosis, Bone Neoplasms surgery, Diagnosis, Differential, Ear Neoplasms diagnosis, Ear Neoplasms surgery, Endoscopy, Follow-Up Studies, Humans, Knee Joint diagnostic imaging, Knee Joint surgery, Male, Melanoma diagnosis, Melanoma surgery, Middle Aged, Neoplasm Recurrence, Local, Palliative Care, Retrospective Studies, Synovectomy, Bone Neoplasms secondary, Ear Neoplasms pathology, Knee Joint pathology, Melanoma secondary, Synovial Membrane pathology
- Abstract
Melanoma can metastasize to almost every organ and tissue. Although bone metastases have been reported frequently, the authors are aware of only a single report of intra-articular synovial metastasis. A case of metastatic melanoma, mimicking degenerative medial meniscal tear of the right knee, is presented. Further examination revealed asymptomatic metastases in the liver, subcutaneous tissue, and left trochanter minor. Arthroscopic examination revealed widespread synovial metastasis and a palliative arthroscopic synovectomy was performed.
- Published
- 1999
- Full Text
- View/download PDF
37. Antibiotic-impregnated plaster of Paris beads. Trials with teicoplanin.
- Author
-
Dacquet V, Varlet A, Tandogan RN, Tahon MM, Fournier L, Jehl F, Monteil H, and Bascoulergue G
- Subjects
- Anti-Bacterial Agents analysis, Bacillus subtilis drug effects, Chromatography, High Pressure Liquid, Drug Carriers, Drug Evaluation, Preclinical, Glycopeptides administration & dosage, Glycopeptides analysis, Microbial Sensitivity Tests methods, Staphylococcus aureus drug effects, Sterilization methods, Teicoplanin, Time Factors, Anti-Bacterial Agents administration & dosage, Calcium Sulfate
- Abstract
Teicoplanin-impregnated plaster of Paris beads were made and in vitro release properties were studied. Teicoplanin was released in an initial massive dose, with a rapid decline during the first three days, followed by a slowly declining prolonged release up to 30 days. The release tested by diffusion in gelose and high-performance liquid chromatography was found to be 21.4% and 28.2%, respectively, of the amount theoretically present in the beads. Plaster of Paris is a resorbable, nontoxic biomaterial that has already been used to fill dead spaces in bone and deliver antibiotics in the treatment of chronic osteomyelitis. The addition of teicoplanin, a new antistaphylococcal agent with low known bacterial resistance, is a promising alternative. Follow-up tests in vivo, simulating local conditions of the osteomyelitic bone, are necessary to prove efficacy.
- Published
- 1992
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.