265 results on '"Tanaka, Nobutada"'
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2. The Diverse Binding Modes Explain the Nanomolar Levels of Inhibitory Activities Against 1-Deoxy-d-Xylulose 5-Phosphate Reductoisomerase from Plasmodium falciparum Exhibited by Reverse Hydroxamate Analogs of Fosmidomycin with Varying N -Substituents.
3. Structural basis for an exceptionally strong preference for asparagine residue at the S2 subsite of Stenotrophomonas maltophilia dipeptidyl peptidase 7
4. A water-mediated hydrogen-bond network facilitates an exceptionally strong preference for asparagine in the S2 subsite of dipeptidyl peptidase 7 from Stenotrophomonas maltophilia
5. The stability of NPM1 oligomers regulated by acidic disordered regions controls the quality of liquid droplets
6. Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase
7. Inhibition of the Non-Mevalonate Isoprenoid Pathway by Reverse Hydroxamate Analogues of Fosmidomycin
8. Over 40 Years of Fosmidomycin Drug Research: A Comprehensive Review and Future Opportunities
9. Design and Pharmacological Chaperone Effects of N‑(4′-Phenylbutyl)-DAB Derivatives Targeting the Lipophilic Pocket of Lysosomal Acid α‑Glucosidase.
10. Site-Directed Mutagenesis of Residues in Coenzyme-Binding Domain and Active Site of Mouse Lung Carbonyl Reductase
11. Synthesis and Evaluation of Habiterpenol Analogs
12. 5-C-Branched Deoxynojirimycin: Strategy for Designing a 1-Deoxynojirimycin-Based Pharmacological Chaperone with a Nanomolar Affinity for Pompe Disease
13. Introduction of C-alkyl branches to l-iminosugars changes their active site binding orientation
14. Molecular determinants for the stereospecific reduction of 3-ketosteroids and reactivity towards all- trans-retinal of a short-chain dehydrogenase/reductase (DHRS4)
15. Novel angular naphthopyrone formation by Arp1p dehydratase involved in Aspergillus fumigatus melanin biosynthesis
16. Scalable purification and characterization of the extracellular domain of human autotaxin from prokaryotic cells
17. Molecular Basis for Peroxisomal Localization of Tetrameric Carbonyl Reductase
18. Characterization of human DHRS4: An inducible short-chain dehydrogenase/reductase enzyme with 3β-hydroxysteroid dehydrogenase activity
19. Structural and mutational analyses of dipeptidyl peptidase 11 from Porphyromonas gingivalis reveal the molecular basis for strict substrate specificity
20. Structural basis for recognition of 2′,5′‐linked oligoadenylates by human ribonuclease L
21. The Autocrine Motility Factor (AMF) and AMF-receptor Combination Needs Sugar Chain Recognition Ability and Interaction Using the C-terminal Region of AMF
22. Crystal Structures of Mouse Autocrine Motility Factor in Complex with Carbohydrate Phosphate Inhibitors Provide Insight into Structure–Activity Relationship of the Inhibitors
23. A pentagonal hydrogen-bond network facilitates an exceptional preference for asparagine in the S2 subsite of Stenotrophomonas maltophilia dipeptidyl peptidase 7
24. Functional Characterization of 2′,5′-Linked Oligoadenylate Binding Determinant of Human RNase L
25. Differential Regulation of Phosphoglucose Isomerase/Autocrine Motility Factor Activities by Protein Kinase CK2 Phosphorylation
26. Mutational analyses of Plasmodium falciparum and human S-adenosylhomocysteine hydrolases
27. Crystal Structure of the Catalytic Fragment of Human Brain 2′,3′-Cyclic-nucleotide 3′-Phosphodiesterase
28. Structural basis for recognition of cognate tRNA by tyrosyl-tRNA synthetase from three kingdoms
29. Crystal structures of the binary and ternary complexes of 7-alpha-hydroxysteroid dehydrogenase from Escherichia coli
30. Crystal Structure of S-Adenosyl- l-Homocysteine Hydrolase from the Human Malaria Parasite Plasmodium falciparum
31. Crystal Structures of Creatininase Reveal the Substrate Binding Site and Provide an Insight into the Catalytic Mechanism
32. The enzymatic activity of phosphoglucose isomerase is not required for its cytokine function
33. Crystal structure of glutathione-independent formaldehyde dehydrogenase
34. Novel inhibitor for prolyl aminopeptidase from Serratia marcescens and studies on the mechanism of substrate recognition of the enzyme using the inhibitor
35. Site-Directed Mutagenesis of Residues in Coenzyme-Binding Domain and Active Site of Mouse Lung Carbonyl Reductase
36. Analysis on the Substrate Specificity of Recombinant Human Acyl-CoA Synthetase ACSL4 Variants
37. Crystal Structure of Formaldehyde Dehydrogenase from Pseudomonas putida: the Structural Origin of the Tightly Bound Cofactor in Nicotinoprotein Dehydrogenases
38. Inhibition Mechanism of Cytokine Activity of Human Autocrine Motility Factor Examined by Crystal Structure Analyses and Site-directed Mutagenesis Studies
39. The Mechanism of Substrate Recognition of Pyroglutamyl-peptidase I from Bacillus amyloliquefaciens as Determined by X-ray Crystallography and Site-directed Mutagenesis
40. Crystal structure of a plant ribonuclease, RNase LE
41. Crystal structures of a bacterial dipeptidyl peptidase IV reveal a novel substrate recognition mechanism distinct from that of mammalian orthologues
42. Periplasmic form of dipeptidyl aminopeptidase IV fromPseudoxanthomonas mexicanaWO24: purification, kinetic characterization, crystallization and X-ray crystallographic analysis
43. S46 Peptidases are the First Exopeptidases to be Members of Clan PA
44. Structural and mutational analyses of dipeptidyl peptidase 11 from Porphyromonas gingivalis reveal the molecular basis for strict substrate specificity
45. Structural and Functional Studies of Dipeptidyl Aminopeptidase from Non-Fermenting Gram-Negative Rods
46. The impact of a single-nucleotide mutation of bgl2 on cellulase induction in a Trichoderma reesei mutant
47. Structural insights into the reaction mechanism of S-adenosyl-L-homocysteine hydrolase
48. Periplasmic form of dipeptidyl aminopeptidase IV from Pseudoxanthomonas mexicana WO24: purification, kinetic characterization, crystallization and X-ray crystallographic analysis.
49. Crystallization and preliminary X-ray crystallographic studies of dipeptidyl peptidase 11 fromPorphyromonas gingivalis
50. Binding Modes of Reverse Fosmidomycin Analogs toward the Antimalarial Target IspC
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