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4. Respiratory microorganisms in acute pharyngitis patients: Identification, antibiotic prescription patterns and appropriateness, and antibiotic resistance in private primary care, central Malaysia

Author

Bo, Zhuang Mian, primary, Tan, Wei Keat, additional, Chong, Christina Shook Cheng, additional, Lye, Munn Sann, additional, Parmasivam, Seshatharran, additional, Pang, Shu Ting, additional, Satkunananthan, Shobha Elizabeth, additional, Chong, Hui Yee, additional, Malek, Ameen, additional, Al-khazzan, Batool Abdulhafidh Ahmed Mohammed, additional, Sim, Benedict Lim Heng, additional, Lee, Christopher Kwok Chong, additional, Lim, Renee Lay Hong, additional, and Lim, Crystale Siew Ying, additional

Published
2022
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5. Living with COVID-19: The road ahead

Author

Wei, Wycliffe Enli, primary, Tan, Wei Keat, additional, Cook, Alex Richard, additional, Hsu, Li Yang, additional, Teo, Yik Ying, additional, and Lee, Vernon Jian Ming, additional

Published
2021
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7. Additional file 2 of Frequent horizontal and mother-to-child transmission may contribute to high prevalence of STLV-1 infection in Japanese macaques

Author

Murata, Megumi, Jun-Ichirou Yasunaga, Washizaki, Ayaka, Seki, Yohei, Kuramitsu, Madoka, Tan, Wei Keat, Hu, Anna, Kazu Okuma, Hamaguchi, Isao, Mizukami, Takuo, Matsuoka, Masao, and Akari, Hirofumi

Abstract

Additional file 2: Figure S2. Distribution of STLV-1 proviral loads (PVLs) in the JMs positive for STLV-1 proviral DNA. The X-axis indicates PVLs ranging from 0.01%–20%, with PVLs of 0.64%–1.28% at the maximum number of individuals. The Y-axis shows the number of individuals in each PVL group.

Published
2020
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8. Additional file 1 of Frequent horizontal and mother-to-child transmission may contribute to high prevalence of STLV-1 infection in Japanese macaques

Author

Murata, Megumi, Jun-Ichirou Yasunaga, Washizaki, Ayaka, Seki, Yohei, Kuramitsu, Madoka, Tan, Wei Keat, Hu, Anna, Kazu Okuma, Hamaguchi, Isao, Mizukami, Takuo, Matsuoka, Masao, and Akari, Hirofumi

Abstract

Additional file 1: Figure S1 Distribution of anti-STLV-1 antibody titers (ABTs) in seropositive JMs. The X-axis represents antibody titers ranging from 16–262144, with an ABT of 8192 at the maximum number of individuals. The Y-axis represents the number of individuals in each antibody titer.

Published
2020
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9. Additional file 3 of Frequent horizontal and mother-to-child transmission may contribute to high prevalence of STLV-1 infection in Japanese macaques

Author

Murata, Megumi, Jun-Ichirou Yasunaga, Washizaki, Ayaka, Seki, Yohei, Kuramitsu, Madoka, Tan, Wei Keat, Hu, Anna, Kazu Okuma, Hamaguchi, Isao, Mizukami, Takuo, Matsuoka, Masao, and Akari, Hirofumi

Subjects
viruses
Abstract

Additional file 3: Figure S3 a, b and c. Alignments of the STLV-1 partial nucleotide sequences in a JM troop. Total of 12 proviral DNA-positive JMs in troop D were examined as a representative (age ranges: 2-21 years of age; sex: 4 male and 8 female) for the viral sequences of first 600 nucleotides of STLV-1 3’LTR (a) and tax exon3 (b) as well as 1447 nucleotides of entire STLV-1 env (c) by direct sequencing. The results of the alignments demonstrated only one nucleotide variation in both 3’LTR and env but not tax exon3 region for each JMs.

Published
2020
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16. Does low-molecular-weight heparin improve live birth rates in pregnant women with thrombophilic disorders? A systematic review.

Author

Tan WK, Lim SK, Tan LK, and Bauptista D

Subjects
Female, Humans, Pregnancy, Pregnancy Outcome, Thrombophilia drug therapy, Treatment Outcome, Heparin, Low-Molecular-Weight therapeutic use, Pregnancy Complications, Hematologic drug therapy, Thrombophilia complications
Abstract

Introduction: Pregnancies in women with thrombophilia are associated with a higher risk of obstetric complications. We systematically reviewed the findings of relevant randomised controlled trials (RCTs) with the aim of investigating the effectiveness of low-molecular-weight heparins (LMWHs) in pregnant women with inherited thrombophilic disorders and its effect on the incidence of live births in these patients., Methods: The MEDLINE-PubMed and Cochrane CENTRAL databases from 2000 to 2010 were searched using a combination of keywords, including low-molecular-weight heparin, enoxaparin, pregnancy, live birth and thrombophilia. Studies were included if they were RCTs assessing the effect of anticoagulant treatment on live birth rates in women with a history of miscarriage without apparent causes other than thrombophilic disorder. Interventions included LMWH, with or without aspirin, aspirin alone or placebo controlled for the prevention of adverse pregnancy outcome., Results: 43 articles with seven RCTs were retrieved following the initial search, of which four studies had to be excluded as they assessed thromboembolic events as the final outcome (n = 1), focused on idiopathic recurrent miscarriages (n = 1), compared efficacy and safety of two doses of enoxaparin (n = 1), and examined patients with or without thrombophilic disorder (n = 1). Pooled data from the remaining three RCTs showed no significant difference in the improvement of live birth rates following LMWH interventions (p = 0.15)., Conclusion: At present, the use of LMWH in women with inherited thrombophilia with recurrent pregnancy loss is not indicated. Large randomised placebo-controlled trials are further needed to prove the effectiveness of LMWH in these patients.

Published
2012

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