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20. Camouflaged Instance Segmentation In-The-Wild: Dataset, Method, and Benchmark Suite

Author

Le, Trung-Nghia, Cao, Yubo, Nguyen, Tan-Cong, Le, Minh-Quan, Nguyen, Khanh-Duy, Do, Thanh-Toan, Tran, Minh-Triet, and Nguyen, Tam V.

Subjects
Computer Science - Computer Vision and Pattern Recognition
Abstract

This paper pushes the envelope on decomposing camouflaged regions in an image into meaningful components, namely, camouflaged instances. To promote the new task of camouflaged instance segmentation of in-the-wild images, we introduce a dataset, dubbed CAMO++, that extends our preliminary CAMO dataset (camouflaged object segmentation) in terms of quantity and diversity. The new dataset substantially increases the number of images with hierarchical pixel-wise ground truths. We also provide a benchmark suite for the task of camouflaged instance segmentation. In particular, we present an extensive evaluation of state-of-the-art instance segmentation methods on our newly constructed CAMO++ dataset in various scenarios. We also present a camouflage fusion learning (CFL) framework for camouflaged instance segmentation to further improve the performance of state-of-the-art methods. The dataset, model, evaluation suite, and benchmark will be made publicly available on our project page: https://sites.google.com/view/ltnghia/research/camo_plus_plus, Comment: TIP acceptance. Project page: https://sites.google.com/view/ltnghia/research/camo_plus_plus

Published
2021
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22. A Comprehensive Review of Detection Methods for DC Arc Fault Detection in Photovoltaic System

Author

Li, Songnong, Yan, Yao, Xiang, Fei, Lv, Xiaohong, Wang, Yi, Tan, Cong, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Xie, Kaigui, editor, Hu, Jianlin, editor, Yang, Qingxin, editor, and Li, Jian, editor

Published
2023
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33. Semi-supervised Organ Segmentation with Mask Propagation Refinement and Uncertainty Estimation for Data Generation

Author

Pham, Minh-Khoi, Nguyen-Ho, Thang-Long, Dao, Thao Thi Phuong, Nguyen, Tan-Cong, Tran, Minh-Triet, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Ma, Jun, editor, and Wang, Bo, editor

Published
2022
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39. A study protocol of a randomized phase II trial of perioperative chemoimmunotherapy verses perioperative chemoimmunotherapy plus preoperative chemoradiation for locally advanced gastric (G) or gastroesophageal junction (GEJ) adenocarcinoma: the NeoRacing study

Author

Zhou, Menglong, Yang, Wang, Xuan, Yan, Zou, Wei, Wang, Yaqi, Zhang, Zhiyuan, Zhang, Jing, Mo, Miao, Zhou, Changming, Liu, Yuan, Zhang, Wenming, Zhang, Zhaozhen, He, Yiping, Weng, Weiwei, Tan, Cong, Wang, Lei, Huang, Dan, Sheng, Weiqi, Li, Huanhuan, Zhu, Hui, Wang, Yan, Shen, Lijun, Zhang, Hui, Wan, Juefeng, Li, Guichao, Huang, Hua, Wang, Yanong, Zhang, Zhen, Liu, Xiaowen, and Xia, Fan

Published
2022
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42. Preclinical characterization of MTX-101: a novel bispecific CD8 Treg modulator that restores CD8 Treg functions to suppress pathogenic T cells in autoimmune diseases.

Author

Gardell, Jennifer L., Maurer, Meghan E., Childs, Monica M., Pham, Minh N., Meengs, Brent, Julien, Susan H., Tan, Cong, Boster, Daniel R., Quach, Phoenicia, Therriault, Jon H., Hermansky, Gleda, Patton, Daniel T., Bowser, Justin, Chen, Alex, Morgan, Nadine N., Gilbertson, Emily A., Bogatzki, Lisa, Encarnacion, Kaelen, McMahan, Catherine J., and Crane, Courtney A.

Subjects
REGULATORY T cells, GRAFT versus host disease, MONONUCLEAR leukocytes, BACTERIAL antigens, DELAYED onset of disease
Abstract

Introduction: Regulatory CD8 T cells (CD8 Treg) are responsible for the selective killing of self-reactive and pathogenic CD4 T cells. In autoimmune disease, CD8 Treg may accumulate in the peripheral blood but fail to control the expansion of pathogenic CD4 T cells that subsequently cause tissue destruction. This CD8 Treg dysfunction is due in part to the expression of inhibitory killer immunoglobulin-like receptors (KIR; KIR2DL isoforms [KIR2DL1, KIR2DL2, and KIR2DL3]); these molecules serve as autoimmune checkpoints and limit CD8 Treg activation. Methods: Here we describe the pre-clinical characterization of MTX-101, a bispecific antibody targeting inhibitory KIR and CD8. Using human peripheral blood mononuculear cells (PBMC) derived from healthy donors and autoimmune patients, humanized mouse models, and human derived tissue organoids, we evaluated the molecular mechanisms and functional effects of MTX-101. Results: By binding to KIR, MTX-101 inhibited KIR signaling that can restore CD8 Treg ability to eliminate pathogenic CD4 T cells. MTX-101 bound and activated CD8 Treg in human peripheral blood mononuclear cells (PBMC), resulting in increased CD8 Treg cytolytic capacity, activation, and prevalence. Enhancing CD8 Treg function with MTX-101 reduced pathogenic CD4 T cell expansion and inflammation, without increasing pro-inflammatory cytokines or activating immune cells that express either target alone. MTX-101 reduced antigen induced epithelial cell death in disease affected tissues, including in tissue biopsies from individuals with autoimmune disease (i.e., celiac disease, Crohn's disease). The effects of MTX-101 were specific to autoreactive CD4 T cells and did not suppress responses to viral and bacterial antigens. In a human PBMC engrafted Graft versus Host Disease (GvHD) mouse model of acute inflammation, MTX-101 bound CD8 Treg and delayed onset of disease. MTX-101 induced dose dependent binding, increased prevalence and cytolytic capacity of CD8 Treg, as well as increased CD4 T cell death. MTX-101 selectively bound CD8 Treg without unwanted immune cell activation or increase of pro-inflammatory serum cytokines and exhibited an antibody-like half-life in pharmacokinetic and exploratory tolerability studies performed using IL-15 transgenic humanized mice with engrafted human lymphocytes, including CD8 Treg at physiologic ratios. Conclusion: Collectively, these data support the development of MTX-101 for the treatment of autoimmune diseases. [ABSTRACT FROM AUTHOR]

Published
2024
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45. CCBANet: Cascading Context and Balancing Attention for Polyp Segmentation

Author

Nguyen, Tan-Cong, Nguyen, Tien-Phat, Diep, Gia-Han, Tran-Dinh, Anh-Huy, Nguyen, Tam V., Tran, Minh-Triet, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, de Bruijne, Marleen, editor, Cattin, Philippe C., editor, Cotin, Stéphane, editor, Padoy, Nicolas, editor, Speidel, Stefanie, editor, Zheng, Yefeng, editor, and Essert, Caroline, editor

Published
2021
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46. Integration Analysis of Single‐Cell Multi‐Omics Reveals Prostate Cancer Heterogeneity

Author

Bian, Xiaojie, primary, Wang, Wenfeng, additional, Abudurexiti, Mierxiati, additional, Zhang, Xingming, additional, Ma, Weiwei, additional, Shi, Guohai, additional, Du, Leilei, additional, Xu, Midie, additional, Wang, Xin, additional, Tan, Cong, additional, Sun, Hui, additional, He, Xiadi, additional, Zhang, Chenyue, additional, Zhu, Yao, additional, Zhang, Min, additional, Ye, Dingwei, additional, and Wang, Jianhua, additional

Published
2024
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50. Construction of a map-based reference genome sequence for barley, Hordeum vulgare L.

Author

Beier, Sebastian, Himmelbach, Axel, Colmsee, Christian, Zhang, Xiao-Qi, Barrero, Roberto A, Zhang, Qisen, Li, Lin, Bayer, Micha, Bolser, Daniel, Taudien, Stefan, Groth, Marco, Felder, Marius, Hastie, Alex, Šimková, Hana, Staňková, Helena, Vrána, Jan, Chan, Saki, Muñoz-Amatriaín, María, Ounit, Rachid, Wanamaker, Steve, Schmutzer, Thomas, Aliyeva-Schnorr, Lala, Grasso, Stefano, Tanskanen, Jaakko, Sampath, Dharanya, Heavens, Darren, Cao, Sujie, Chapman, Brett, Dai, Fei, Han, Yong, Li, Hua, Li, Xuan, Lin, Chongyun, McCooke, John K, Tan, Cong, Wang, Songbo, Yin, Shuya, Zhou, Gaofeng, Poland, Jesse A, Bellgard, Matthew I, Houben, Andreas, Doležel, Jaroslav, Ayling, Sarah, Lonardi, Stefano, Langridge, Peter, Muehlbauer, Gary J, Kersey, Paul, Clark, Matthew D, Caccamo, Mario, Schulman, Alan H, Platzer, Matthias, Close, Timothy J, Hansson, Mats, Zhang, Guoping, Braumann, Ilka, Li, Chengdao, Waugh, Robbie, Scholz, Uwe, Stein, Nils, and Mascher, Martin

Subjects
Hordeum, Chromosome Mapping, Sequence Analysis, Genome, Plant, Genome, Plant
Abstract

Barley (Hordeum vulgare L.) is a cereal grass mainly used as animal fodder and raw material for the malting industry. The map-based reference genome sequence of barley cv. 'Morex' was constructed by the International Barley Genome Sequencing Consortium (IBSC) using hierarchical shotgun sequencing. Here, we report the experimental and computational procedures to (i) sequence and assemble more than 80,000 bacterial artificial chromosome (BAC) clones along the minimum tiling path of a genome-wide physical map, (ii) find and validate overlaps between adjacent BACs, (iii) construct 4,265 non-redundant sequence scaffolds representing clusters of overlapping BACs, and (iv) order and orient these BAC clusters along the seven barley chromosomes using positional information provided by dense genetic maps, an optical map and chromosome conformation capture sequencing (Hi-C). Integrative access to these sequence and mapping resources is provided by the barley genome explorer (BARLEX).

Published
2017

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